GHS Classification Result
GENERAL INFORMATION
REFERENCE INFORMATION
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTES:
Updated date:
GENERAL INFORMATION
| Item | Information |
|---|---|
| CAS number | 143-18-0 |
| Chemical name | Potassium (Z)-oleate |
| Substance ID | 23A5156 |
| Fiscal year of classification conducted | FY2011 |
| Classifier(s) (Ministries) | Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE） |
| New/Revised | New |
| Download in Excel format | Excel file |
| Item | Information |
|---|---|
| Guidance used for classification (External link) |
Physical Hazards & Health Hazards: GHS Classification Guidance by the Japanese Government （July, 2010）
Environmental Hazards: UN GHS Document （4th revised edition） |
| Definitions / Abbreviations (Excel file) | Definitions / Abbreviations |
| Model Label by MHLW (External link) | MHLW Website （in Japanese Only） |
| Model SDS by MHLW (External link) | MHLW Website （in Japanese Only） |
| OECD/eChemPortal (External link) | eChemPortal |
| Hazard class | Classification |
Pictogram (Code: symbol) Signal word |
Code (Hazard statement) |
Code (Precautionary statement) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable | - | - | - | There are no chemical groups associated with explosive properties present in the molecule. |
| 2 | Flammable gases （including chemically unstable gases） | Not applicable | - | - | - | "Solids" according to GHS definition. |
| 3 | Aerosols | Not applicable | - | - | - | Not an aerosol product. |
| 4 | Oxidizing gases | Not applicable | - | - | - | "Solids" according to GHS definition. |
| 5 | Gases under pressure | Not applicable | - | - | - | "Solids" according to GHS definition. |
| 6 | Flammable liquids | Not applicable | - | - | - | "Solids" according to GHS definition. |
| 7 | Flammable solids | Classification not possible | - | - | - | No data. |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | There are no chemical groups present in the molecule associated with explosive or self-reactive properties. |
| 9 | Pyrophoric liquids | Not applicable | - | - | - | "Solids" according to GHS definition. |
| 10 | Pyrophoric solids | Classification not possible | - | - | - | No data. |
| 11 | Self-heating substances and mixtures | Classification not possible | - | - | - | No data. |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified | - | - | - | It contains a metal (K), but it is judged to be stable in the water from water solubility of 25 g/100 cc (HSDB (2002)). |
| 13 | Oxidizing liquids | Not applicable | - | - | - | "Solids" according to GHS definition. |
| 14 | Oxidizing solids | Not applicable | - | - | - |
An organic compound contains oxygen which is not chemically bonded to elements other than hydrogen or carbon. Furthermore, it is "Not applicable" because potassium and oxygen are ionically bonded. |
| 15 | Organic peroxides | Not applicable | - | - | - | An organic compound that does not contain -O-O- structure. |
| 16 | Corrosive to metals | Classification not possible | - | - | - | No established test method suitable for solid substances. |
| Hazard class | Classification |
Pictogram (Code: symbol) Signal word |
Code (Hazard statement) |
Code (Precautionary statement) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Classification not possible | - | - | - | An LD50 value of >5000 mg/kg for rats was reported for a preparation of this substance (Pesticide safety information, Japanese Journal of Pesticide Science Vo.24 No.4 (1999), corresponding to List 2), but the classification is not possible due to an unknown content of this substance in the preparation. |
| 1 | Acute toxicity （Dermal） | Classification not possible | - | - | - | An LD50 value of >2000 mg/kg for rats was reported for a preparation of this substance (Pesticide safety information, Japanese Journal of Pesticide Science Vo.24 No.4 (1999)), but the classification is not possible due to an unknown content of this substance in the preparation. |
| 1 | Acute toxicity （Inhalation: Gases） | Not applicable | - | - | - | "Solids" according to GHS definition. |
| 1 | Acute toxicity （Inhalation: Vapours） | Classification not possible | - | - | - | No data. |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Classification not possible | - | - | - | An LC50 value of 5.61 mg/L for rats was reported for a preparation of this substance (Pesticide safety information, Japanese Journal of Pesticide Science Vo.24 No.4 (1999)), but the classification is not possible due to an unknown content of this substance in the preparation. |
| 2 | Skin corrosion/irritation | Category 2 |  |
H315 |
P302+P352 P332+P313 P264 P280 P321 P362 |
In an occlusive test applied 0.5 mL of a preparation of this substance to rabbit skin for 4 hours (Guidelines by Ministry of Agriculture, Forestry and Fisheries, Draize method), moderate to severe erythema was observed in all animals 1 hour after removal of patches. And scab formation observed after 24 hours turned into erosion after falling off on day 6 to 9 and showed recovery tendency afterward. As a result, the test substance was judged to have moderate primary irritation to rabbit skin tissues (Pesticide safety information, Japanese Journal of Pesticide Science Vo.24 No.4 (1999): List 2). Therefore, it was classified in Category 2. |
| 3 | Serious eye damage/eye irritation | Category 2A | |
H319 |
P305+P351+P338 P337+P313 P264 P280 |
In a test applied 0.1 mL of a preparation of this substance to rabbit eyes (Guidelines by Ministry of Agriculture, Forestry and Fisheries, Draize method), corneal opacity observed in all animals 1 hour after application still remained in one animal after 21 days. Congestion and swelling of the iris (score 1) were observed in one animal, and redness (redness score 1) observed in all animals 1 hour after application reversed by day 16 except one animal (Pesticide safety information, Japanese Journal of Pesticide Science Vol.24 No.4 (1999)). Because the test substance was judged to have moderate irritation to rabbit eye mucosa from the above, it was classified in Category 2A. |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | No data. |
| 4 | Skin sensitization | Classification not possible | - | - | - |
It was judged to be not skin sensitizing because noted responses in a challenge after induction by a preparation of this substance were not observed in a maximization test in guinea pigs (Pesticide safety information, Japanese Journal of Pesticide Science Vo.24 No.4 (1999)). But it was classified as "Classification not possible" due to no positive rate data and the information corresponding to List 2. |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - |
The classification is not possible due to no in vivo test data. Besides, an Ames test and a chromosomal aberration test using CHL cells reported negative results as in vitro tests (NTP DB (1991), Pesticide safety information, Japanese Journal of Pesticide Science Vo.24 No.4 (1999)). |
| 6 | Carcinogenicity | Classification not possible | - | - | - | No data. |
| 7 | Reproductive toxicity | Classification not possible | - | - | - | No data. |
| 8 | Specific target organ toxicity - Single exposure | Classification not possible | - | - | - |
Lack of data. Besides, there is the information that inhalation of dust causes irritation to nose and throat, coughing, and sneezing (HSDB (2002)), but details of respiratory tract irritation are unknown. |
| 9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | No data. |
| 10 | Aspiration hazard | Classification not possible | - | - | - | No data. |
| Hazard class | Classification |
Pictogram (Code: symbol) Signal word |
Code (Hazard statement) |
Code (Precautionary statement) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Category 1 |  |
H400 |
P273 P391 P501 |
It was classified in Category 1 from 48-hour EC50 = 0.57 mg/L for crustacea (Daphnia pulex) (AQUIRE, 2012). |
| 11 | Hazardous to the aquatic environment （Long-term） | Category 1 | |
H410 |
P273 P391 P501 |
Reliable chronic toxicity data are not obtained. Because appropriate data on rapid degradability were not obtained and it was classified in Category 1 in acute toxicity, it was classified in Category 1. |
| 12 | Hazardous to the ozone layer | Classification not possible | - | - | - | This substance is not listed in Annexes to the Montreal Protocol. |
NOTES:
|
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Updated date:
|
2016/11/16 Addition of Rationale for the classification |