GHS Classification Result
GENERAL INFORMATION
REFERENCE INFORMATION
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTES:
Updated date:
GENERAL INFORMATION
| Item | Information |
|---|---|
| CAS number | 617-94-7 |
| Chemical name | 2-Phenyl-2-propanol |
| Substance ID | 23A5158 |
| Fiscal year of classification conducted | FY2011 |
| Classifier(s) (Ministries) | Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE） |
| New/Revised | New |
| Download in Excel format | Excel file |
| Item | Information |
|---|---|
| Guidance used for classification (External link) |
Physical Hazards & Health Hazards: GHS Classification Guidance by the Japanese Government （July, 2010）
Environmental Hazards: UN GHS Document （4th revised edition） |
| Definitions / Abbreviations (Excel file) | Definitions / Abbreviations |
| Model Label by MHLW (External link) | MHLW Website （in Japanese Only） |
| Model SDS by MHLW (External link) | MHLW Website （in Japanese Only） |
| OECD/eChemPortal (External link) | eChemPortal |
| Hazard class | Classification |
Symbol Signal word |
Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable | - | - | - | There are no chemical groups associated with explosive properties present in the molecule. |
| 2 | Flammable gases （including chemically unstable gases） | Not applicable | - | - | - | "Solids" according to GHS definition. |
| 3 | Aerosols | Not applicable | - | - | - | Not an aerosol product. |
| 4 | Oxidizing gases | Not applicable | - | - | - | "Solids" according to GHS definition. |
| 5 | Gases under pressure | Not applicable | - | - | - | "Solids" according to GHS definition. |
| 6 | Flammable liquids | Not applicable | - | - | - | "Solids" according to GHS definition. |
| 7 | Flammable solids | Classification not possible | - | - | - | No data. |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | Containing neither chemical groups related to explosibility nor those related to self-reactivity. |
| 9 | Pyrophoric liquids | Not applicable | - | - | - | "Solids" according to GHS definition. |
| 10 | Pyrophoric solids | Classification not possible | - | - | - | No data. |
| 11 | Self-heating substances and mixtures | Classification not possible | - | - | - | No established test method suitable for solid substances with a melting point of 140 degrees C or lower. |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | Not containing metals or semimetals (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At). |
| 13 | Oxidizing liquids | Not applicable | - | - | - | "Solids" according to GHS definition. |
| 14 | Oxidizing solids | Not applicable | - | - | - | An organic compound that does not contain fluorine or chlorine but contains oxygen, and the element is not chemically bonded to elements other than carbon or hydrogen. |
| 15 | Organic peroxides | Not applicable | - | - | - | An organic compound that does not contain -O-O- structure. |
| 16 | Corrosive to metals | Classification not possible | - | - | - | The classification is not possible because a solid with a melting point of 55 degrees C or lower has no data. |
| Hazard class | Classification |
Symbol Signal word |
Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Category 4 |  |
H302 |
P301+P312 P264 P270 P330 P501 |
It was classified in Category 4 because the higher hazard category in two LD50 values [2250 mg/kg and 1042 mg/kg] (HSDB（2002）), which correspond to Category 4 and to "Not classified" in JIS classification, was adopted. |
| 1 | Acute toxicity （Dermal） | Category 3 |  |
H311 |
P302+P352 P280 P312 P322 P361 P363 P405 P501 |
On the basis of an LD50 value of 974 mg/kg bw for rats (HSDB (2002)), it was classified in Category 3. |
| 1 | Acute toxicity （Inhalation: Gases） | Not applicable | - | - | - | "Solids" according to GHS definition. |
| 1 | Acute toxicity （Inhalation: Vapours） | Classification not possible | - | - | - |
The classification is not possible because the category can not be determined only from data in which no mortality in 8-hour inhalation exposure to saturated vapour was reported (HSDB (2002)). Besides, an LC50 value is estimated at > 5.39 mg/L from 5.39 mg/L which is a converted concentration to a 4-hour equivalent in 8-hour exposure to the saturated vapour pressure concentration (3.81 mg/L). |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Classification not possible | - | - | - | No data. |
| 2 | Skin corrosion/irritation | Classification not possible | - | - | - | Due to lack of data, the classification is not possible, though a test which is not in accordance with the guideline reports that daily application (an unknown application period) of the test substance to the rabbit and guinea pig skins produced mild primary irritation in both animals (HSDB (2002)). |
| 3 | Serious eye damage/eye irritation | Classification not possible | - | - | - | Due to lack of data, the classification is not possible, though a test that is not in accordance with the guideline reports that 15-day application of 0.1 mL to rabbit and guinea pig eyes produced some irritation with erythema, from which both animals completely recovered in 7 to 14 days with no permanent corneal damage. |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | No data. |
| 4 | Skin sensitization | Classification not possible | - | - | - |
Lack of data. The classification is not possible only from a result on a skin sensitization test which reports an indication of skin sensitization in 7 of 55 subjects (a positive rate: 12.7 % (7/55)) (HSDB (2002)). |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | No data. |
| 6 | Carcinogenicity | Classification not possible | - | - | - | No data. |
| 7 | Reproductive toxicity | Classification not possible | - | - | - | No data. |
| 8 | Specific target organ toxicity - Single exposure | Classification not possible | - | - | - |
Lack of data. Besides, this substance affects a central nervous system, and HSDB says that the toxic clinical symptoms after administration to rats and mice were similar to CNS depressants (HSDB (2002)). |
| 9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | No data. |
| 10 | Aspiration hazard | Classification not possible | - | - | - | No data. |
| Hazard class | Classification |
Symbol Signal word |
Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Classification not possible | - | - | - | No data. |
| 11 | Hazardous to the aquatic environment （Long-term） | Classification not possible | - | - | - | No data. |
| 12 | Hazardous to the ozone layer | Classification not possible | - | - | - | This substance is not listed in Annexes to the Montreal Protocol. |
NOTES:
|
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Updated date:
|
2016/7/29 Addition of Rationale for the classification |