GHS Classification Result
GENERAL INFORMATION
REFERENCE INFORMATION
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTES:
Updated date:
GENERAL INFORMATION
| Item | Information |
|---|---|
| CAS number | 76-05-1 |
| Chemical name | Trifluoroacetic acid |
| Substance ID | 23A5163 |
| Fiscal year of classification conducted | FY2011 |
| Classifier(s) (Ministries) | Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE） |
| New/Revised | New |
| Download in Excel format | Excel file |
| Item | Information |
|---|---|
| Guidance used for classification (External link) |
Physical Hazards & Health Hazards: GHS Classification Guidance by the Japanese Government （July, 2010）
Environmental Hazards: UN GHS Document （4th revised edition） |
| Definitions / Abbreviations (Excel file) | Definitions / Abbreviations |
| Model Label by MHLW (External link) | MHLW Website （in Japanese Only） |
| Model SDS by MHLW (External link) | MHLW Website （in Japanese Only） |
| OECD/eChemPortal (External link) | eChemPortal |
| Hazard class | Classification |
Pictogram (Code: symbol) Signal word |
Code (Hazard statement) |
Code (Precautionary statement) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable | - | - | - | There are no chemical groups associated with explosive properties present in the molecule. |
| 2 | Flammable gases （including chemically unstable gases） | Not applicable | - | - | - | "Liquids" according to GHS definition. |
| 3 | Aerosols | Not applicable | - | - | - | Not an aerosol product. |
| 4 | Oxidizing gases | Not applicable | - | - | - | "Liquids" according to GHS definition. |
| 5 | Gases under pressure | Not applicable | - | - | - | "Liquids" according to GHS definition. |
| 6 | Flammable liquids | Not classified | - | - | - | It is non-flammable (Hommel (1996)). |
| 7 | Flammable solids | Not applicable | - | - | - | "Liquids" according to GHS definition. |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | There are no chemical groups present in the molecule associated with explosive or self-reactive properties. |
| 9 | Pyrophoric liquids | Not classified | - | - | - | It is non-flammable (Hommel (1996)). |
| 10 | Pyrophoric solids | Not applicable | - | - | - | "Liquids" according to GHS definition. |
| 11 | Self-heating substances and mixtures | Not classified | - | - | - | It is non-flammable (Hommel (1996)). |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | Not containing metals or semimetals (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At). |
| 13 | Oxidizing liquids | Not applicable | - | - | - | An organic compound does not contain chlorine but contains oxygen and fluorine which are not chemically bonded to elements other than carbon or hydrogen. |
| 14 | Oxidizing solids | Not applicable | - | - | - | "Liquids" according to GHS definition. |
| 15 | Organic peroxides | Not applicable | - | - | - | An organic compound that does not contain -O-O- structure. |
| 16 | Corrosive to metals | Category 1 |  |
H290 |
P234 P390 P406 |
From the information that says "highly corrosive to most metals." (IMDG (2010)), it was classified in Category 1. Besides, there is the information that "it attacks many metals and produces flammable/explosive gas (hydrogen)" (ICSC (J) (2007)). And there is the information that "a pure substance and a concentrated aqueous solution are corrosive to most metals which are not suitable as a container for this substance." (Hommel (1996)) |
| Hazard class | Classification |
Pictogram (Code: symbol) Signal word |
Code (Hazard statement) |
Code (Precautionary statement) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Category 3 |  |
H301 |
P301+P310 P264 P270 P321 P330 P405 P501 |
From an LD50 value of 200 mg/kg for rats (HSDB (2007)), it was classified in Category 3. |
| 1 | Acute toxicity （Dermal） | Classification not possible | - | - | - | No data. |
| 1 | Acute toxicity （Inhalation: Gases） | Not applicable | - | - | - | "Liquids" according to GHS definition. |
| 1 | Acute toxicity （Inhalation: Vapours） | Category 3 | |
H331 |
P304+P340 P403+P233 P261 P271 P311 P321 P405 |
From an LC50 value of 10 mg/L/2h (7.07 mg/L/4h = 1516 ppm/4h) for rats (HSDB (2007)), it was classified in Category 3. Besides, a reference value of gasses as vapour with hardly included mist was applied because the LC50 value (10 mg/L/2h) is lower than 90 % of the saturated vapour pressure concentration (675 mg/L). |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Classification not possible | - | - | - | No data. |
| 2 | Skin corrosion/irritation | Category 1 | |
H314 |
P301+P330+P331 P303+P361+P353 P305+P351+P338 P304+P340 P260 P264 P280 P310 P321 P363 P405 P501 |
From the information that this substance has a pH of 1 (10 g/L) (GESTIS (Access on Nov. 2011)), it was classified in Category 1. Besides, it is classified in C; R35 in EU classification (EC-JRC (ESIS) (Access on Nov. 2011)). |
| 3 | Serious eye damage/eye irritation | Category 1 | |
H318 |
P305+P351+P338 P280 P310 |
From the information that this substance has a pH of 1 (10 g/L) (GESTIS (Access on Nov. 2011)), it was classified in Category 1. Besides, it was classified in Category 1 as a corrosive substance in skin corrosion/irritation. |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | No data. |
| 4 | Skin sensitization | Classification not possible | - | - | - | No data. |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | No data. |
| 6 | Carcinogenicity | Classification not possible | - | - | - | No data. |
| 7 | Reproductive toxicity | Classification not possible | - | - | - |
An oral administration test in rats given 75 or 150 mg/kg on day 10 to 20 of gestation reported that changes in biochemical parameters indicating hepatic and renal functions in serum and urine examinations of newborns were observed but no statistically significant effects on litter size, neonatal survival or postnatal growth were not observed. (HSDB (2007)) But it was classified as "Classification not possible" due to lack of data because effects on sexual function and fertility are unknown only by this data. |
| 8 | Specific target organ toxicity - Single exposure | Classification not possible | - | - | - | No data. |
| 9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | No data. |
| 10 | Aspiration hazard | Classification not possible | - | - | - | No data. |
| Hazard class | Classification |
Pictogram (Code: symbol) Signal word |
Code (Hazard statement) |
Code (Precautionary statement) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Classification not possible | - | - | - | No data. |
| 11 | Hazardous to the aquatic environment （Long-term） | Classification not possible | - | - | - | No data. |
| 12 | Hazardous to the ozone layer | Classification not possible | - | - | - | This substance is not listed in Annexes to the Montreal Protocol. |
NOTES:
|
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Updated date:
|
2016/11/16 Addition of Rationale for the classification |