Item | Information |
---|---|
CAS RN | 80-10-4 |
Chemical Name | Dichlorodiphenylsilane |
Substance ID | 24A6059 |
Classification year (FY) | FY2012 |
Ministry who conducted the classification | Ministry of Health, Labour and Welfare (MHLW)/Ministry of the Environment (MOE) |
New/Revised | New |
Classification result in other fiscal year | |
Download of Excel format | Excel file |
Item | Information |
---|---|
Guidance used for the classification (External link) | Physical Hazards and Health Hazards: GHS Classification Guidance by the Japanese Government (July, 2010) Environmental Hazards: UN GHS Document (4th revised edition) |
UN GHS document (External link) | UN GHS document |
Definitions/Abbreviations (Excel file) | Definitions/Abbreviations |
Model Label by MHLW (External link) | MHLW Website (in Japanese Only) |
Model SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
OECD/eChemPortal (External link) | eChemPortal |
Hazard class | Classification |
Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
1 | Explosives | Not applicable |
- |
- | - | There are no chemical groups associated with explosive properties present in the molecule. |
2 | Flammable gases (including chemically unstable gases) | Not applicable |
- |
- | - | Liquid (GHS definition) |
3 | Aerosols | Not applicable |
- |
- | - | Not aerosol products. |
4 | Oxidizing gases | Not applicable |
- |
- | - | Liquid (GHS definition) |
5 | Gases under pressure | Not applicable |
- |
- | - | Liquid (GHS definition) |
6 | Flammable liquids | Not classified |
- |
- | - | A flash point of 142 deg C [closed-cup] (HSDB (2010)) is above 93 deg C. |
7 | Flammable solids | Not applicable |
- |
- | - | Liquid (GHS definition) |
8 | Self-reactive substances and mixtures | Not applicable |
- |
- | - | There are no chemical groups present in the molecule associated with explosive or self-reactive properties. |
9 | Pyrophoric liquids | Not classified |
- |
- | - | It is classified in Class 8, PG II (UN1769) in UNRTDG and does not correspond to the hazards of the highest precedence, pyrophoric liquids. Therefore, it was classified as "Not classified." |
10 | Pyrophoric solids | Not applicable |
- |
- | - | Liquid (GHS definition) |
11 | Self-heating substances and mixtures | Classification not possible |
- |
- | - | Test methods applicable to liquid substances are not available. |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified |
- |
- | - | It is a compound containing a metalloid (Si), and it is described that it reacts vigorously with water and generates hydrogen chloride (IMDG (2010)), but it does not emit flammable gases. Therefore, it was classified as "Not classified." |
13 | Oxidizing liquids | Classification not possible |
- |
- | - | The substance is an organic compound containing chlorine (but not fluorine or oxygen) which is chemically bonded to the element other than carbon or hydrogen (Si). However, the classification is not possible due to no data. |
14 | Oxidizing solids | Not applicable |
- |
- | - | Liquid (GHS definition) |
15 | Organic peroxides | Not applicable |
- |
- | - | Organic compounds containing no bivalent -O-O- structure. |
16 | Corrosive to metals | Classification not possible |
- |
- | - | No data available. |
Hazard class | Classification |
Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Classification not possible |
- |
- | - |
No data available. Besides, because this substance reacts with water to form corrosive hydrogen chloride, please also refer to the health hazards of hydrogen chloride (CAS RN 7647-01-0). |
1 | Acute toxicity (Dermal) | Category 2 |
Danger |
H310 |
P302+P352
P361+P364 P262 P264 P270 P280 P310 P321 P405 P501 |
It was classified in Category 2 based on an LD50 value of 100 microL/kg (120.4 mg/kg) for rabbits (RTECS (2000): the original article, National Technical Information Service (Springfield, VA 22161): OTS0571886). |
1 | Acute toxicity (Inhalation: Gases) | Not applicable |
- |
- | - | Liquid (GHS definition) |
1 | Acute toxicity (Inhalation: Vapours) | Classification not possible |
- |
- | - | No data available. |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible |
- |
- | - | No data available. |
2 | Skin corrosion/irritation | Category 1 |
Danger |
H314 |
P301+P330+P331
P303+P361+P353 P305+P351+P338 P304+P340 P260 P264 P280 P310 P321 P363 P405 P501 |
It is described that this substance is a corrosive chemical, contact with skin can cause severe burns leading to permanent damage, and after dermal exposure, dermatitis (red, inflamed skin), severe burns, pain, and shock occur (HSDB (2010)). And it is described that an application of chlorosilanes to rabbits caused necrosis, blistering, and sloughing on the skin (HSDB (2010)). Because the above knowledge means that irreversible damage occurs on the skin on contact with this substance, it was classified in Category 1. |
3 | Serious eye damage/eye irritation | Category 1 |
Danger |
H318 |
P305+P351+P338
P280 P310 |
It is described that this substance is a corrosive chemical, contact can cause severe eye burns leading to permanent damage, and contact with this substance may result in irritation, pain, swelling, corneal erosion, and blindness (HSDB (2010)). And it is described that an application of chlorosilanes to rabbits caused severe damage to the cornea and lids in the eye (HSDB (2010)). Because the above knowledge means that irreversible damage occurs in the eye on contact with this substance, it was classified in Category 1. |
4 | Respiratory sensitization | Classification not possible |
- |
- | - | No data available. |
4 | Skin sensitization | Classification not possible |
- |
- | - | No data available. |
5 | Germ cell mutagenicity | Classification not possible |
- |
- | - | No data available. |
6 | Carcinogenicity | Classification not possible |
- |
- | - | No data available. |
7 | Reproductive toxicity | Classification not possible |
- |
- | - | No data available. |
8 | Specific target organ toxicity - Single exposure | Category 2 (respiratory organs) |
Warning |
H371 |
P308+P311
P260 P264 P270 P405 P501 |
As for effects in humans, it is described that acute inhalation exposure may result in sneezing, choking, laryngitis, dyspnea, respiratory tract irritation, and chest pain, and high exposure can cause pulmonary edema and a medical emergency that can be delayed for several hours, leading to death. On the other hand, it is described that bleeding of the nose and gums, ulceration of the nasal and oral mucosa, pulmonary edema, chronic bronchitis, and pneumonia may also occur (HSDB (2010)). It was classified in Category 2 (respiratory organs) based on the above knowledge, which was from List 2 information. |
9 | Specific target organ toxicity - Repeated exposure | Classification not possible |
- |
- | - | No data available. |
10 | Aspiration hazard | Classification not possible |
- |
- | - | No data available. |
Hazard class | Classification |
Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Classification not possible |
- |
- | - | No data available. |
11 | Hazardous to the aquatic environment (Long-term) | Classification not possible |
- |
- | - | No data available. |
12 | Hazardous to the ozone layer | Classification not possible |
- |
- | - | This substance is not listed in the Annexes to the Montreal Protocol. |
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