GHS Classification Result

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GENERAL INFORMATION
Item Information
CAS RN 67762-41-8
Chemical Name Alcohol (C=10-16)
Substance ID 25A0086
Classification year (FY) FY2013
Ministry who conducted the classification Ministry of Health, Labour and Welfare (MHLW)/Ministry of the Environment (MOE)
New/Revised New
Classification result in other fiscal year  
Download of Excel format Excel file

REFERENCE INFORMATION
Item Information
Guidance used for the classification (External link) GHS Classification Guidance by the Japanese Government (July, 2013)
UN GHS document (External link) UN GHS document
Definitions/Abbreviations (Excel file) Definitions/Abbreviations
Model Label by MHLW (External link) MHLW Website (in Japanese Only)
Model SDS by MHLW (External link) MHLW Website (in Japanese Only)
OECD/eChemPortal (External link) eChemPortal

PHYSICAL HAZARDS
Hazard class Classification Pictogram
Signal word
Hazard statement
(code)
Precautionary statement
(code)
Rationale for the classification
1 Explosives Not applicable
-
-
- - There are no chemical groups associated with explosive properties present in the molecule.
2 Flammable gases (including chemically unstable gases) Not applicable
-
-
- - Liquid (GHS definition)
3 Aerosols Not applicable
-
-
- - Not aerosol products.
4 Oxidizing gases Not applicable
-
-
- - Liquid (GHS definition)
5 Gases under pressure Not applicable
-
-
- - Liquid (GHS definition)
6 Flammable liquids Not classified
-
-
- - For the member substances in this category, data on flash points: 126 deg C (closed cup) (IUCLID (2000)) and above 110 deg C (SIDS (2007)) were obtained, therefore it was judged that all substances correspond to "Not classified."
7 Flammable solid Not applicable
-
-
- - Liquid (GHS definition)
8 Self-reactive substances and mixtures Not applicable
-
-
- - There are no chemical groups present in the molecule associated with explosive or self-reactive properties.
9 Pyrophoric liquids Not classified
-
-
- - For the member substances in this category, data on an autoignition temperature: 246 deg C (SIDS (2007)) were obtained, therefore it was judged that all substances do not ignite at normal temperatures.
10 Pyrophoric solids Not applicable
-
-
- - Liquid (GHS definition)
11 Self-heating substances and mixtures Classification not possible
-
-
- - Test methods applicable to liquid substances are not available.
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable
-
-
- - The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13 Oxidizing liquids Not applicable
-
-
- - The substance is an organic compound containing oxygen (but not fluorine or chlorine) which is chemically bonded only to carbon or hydrogen.
14 Oxidizing solids Not applicable
-
-
- - Liquid (GHS definition)
15 Organic peroxides Not applicable
-
-
- - Organic compounds containing no bivalent -O-O- structure in the molecule.
16 Corrosive to metals Classification not possible
-
-
- - No data available.

HEALTH HAZARDS
Hazard class Classification Pictogram
Signal word
Hazard statement
(code)
Precautionary statement
(code)
Rationale for the classification
1 Acute toxicity (Oral) Not classified
-
-
- - It was classified as "Not classified" based on a report on LD50 values of > 2,000 mg/kg, > 5,000 mg/kg, and > 10,000 mg/kg for rats (SIDS (2007)).
1 Acute toxicity (Dermal) Not classified
-
-
- - It was classified as "Not classified" based on reports on LD50 values of > 2,000 mg/kg for rats (SIDS (2007)) and > 11,300 mg/kg for rabbits (IUCLID (2000)).
1 Acute toxicity (Inhalation: Gases) Not applicable
-
-
- - Liquid (GHS definition)
1 Acute toxicity (Inhalation: Vapours) Classification not possible
-
-
- - Classification not possible due to lack of data. Besides, it is described in SIDS (2007) that inhalation of the vapour of long-chained alcohols in the range of C6-C22 does not cause significant toxicity at up to the saturated vapour pressure concentration.
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible
-
-
- - Classification not possible due to lack of data. There is no information on this CAS RN.
2 Skin corrosion/irritation Not classified
-
-
- - It was classified as "Not classified" because it is reported that the average scores after 72 hours for erythema and edema were 0.3 and 0.2 in a skin corrosion test with rabbits according to OECD TG 404, and the symptoms disappeared within seven days (SIDS (2007)).
3 Serious eye damage/eye irritation Not classified
-
-
- - It was classified as "Not classified" because the average scores after 1, 24, 48, and 72 hours were 0.0/110, 0. 0/110, 0.0/110, 0.0/110, respectively in an eye irritation test with rabbits, and no eye irritation was observed (SIDS (2007)).
4 Respiratory sensitization Classification not possible
-
-
- - Classification not possible due to lack of data.
4 Skin sensitization Not classified
-
-
- - It was classified as "Not classified" because it was reported to be negative in both of two maximization tests with guinea pigs (SIDS (2007)).
5 Germ cell mutagenicity Classification not possible
-
-
- - Classification not possible due to lack of data. There are no in vivo data, and as for in vitro, it was negative in a bacterial reverse mutation test (IUCLID (2000)). Besides, it is described in SIDS (2007) that the category of long-chain alcohols including this substance was assessed to be not mutagenic.
6 Carcinogenicity Classification not possible
-
-
- - Classification not possible due to lack of data. There is no information on this CAS RN.
7 Reproductive toxicity Classification not possible
-
-
- - Classification not possible due to lack of data. There is no information on this CAS RN.
8 Specific target organ toxicity - Single exposure Category 3 (Narcotic effects)


Warning
H336 P304+P340
P403+P233
P261
P271
P312
P405
P501
In an oral administration test (2,000 mg/kg) with rats, reversible piloerection, sluggishness, hunching, and blepharospasm were observed (SIDS (2007)). Furthermore, after dermal administration to rats, reversible hyper-reactivity to stimuli was found. From the above results, it was classified in Category 3 (narcotic effects).
9 Specific target organ toxicity - Repeated exposure Classification not possible
-
-
- - In a 28-day oral administration test with rats, only increases in serum ALT and alkaline phosphatase in females were observed at the dose (1,000 mg/kg/day: converted guidance value: 311 mg/kg/day) above the range for Category 2 (SIDS (2007)). Therefore, it corresponds to "Not classified" in the oral route. However, because of no toxicity information on the other routes, it was classified as "Classification not possible" due to lack of data.
10 Aspiration hazard Classification not possible
-
-
- - Classification not possible due to lack of data. There is no information on this CAS RN.

ENVIRONMENTAL HAZARDS
Hazard class Classification Pictogram
Signal word
Hazard statement
(code)
Precautionary statement
(code)
Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Category 1


Warning
H400 P273
P391
P501
From 72-hour ErC50 = 0.1-0.3 mg/L for algae (Pseudokirchneriella subcapitata) (SIDS, 2007), it was classified in Category 1.
11 Hazardous to the aquatic environment (Long-term) Category 1


Warning
H410 P273
P391
P501
If chronic toxicity data are used, then it is classified in Category 2 due to rapid degradability (a degradation rate: 81-91% (SIDS, 2007)), and 72-hour NOEC = 0.058 mg/L for algae (Pseudokirchneriella subcapitata) (SIDS, 2007).
If acute toxicity data are used for a trophic level for which chronic toxicity data are not obtained, then it is classified in Category 1 due to 48-hour EC50 = 0.23-0.28 mg/L for crustacea (Daphnia magna) (SIDS, 2007), and a high bioaccumulation estimate (log Kow = 4.8 (SIDS, 2007)) despite rapid degradability (a degradation rate: 81-91% (SIDS, 2007)).
By drawing a comparison between the above results, it was classified in Category 1.
12 Hazardous to the ozone layer Classification not possible
-
-
- - This substance is not listed in the Annexes to the Montreal Protocol.


NOTE:
  • GHS Classification Result by the Japanese Government is intended to provide a reference for preparing a GHS label or SDS for users. To include the same classification result in a label or SDS for Japan is NOT mandatory.
  • Users can cite or copy this classification result when preparing a GHS label or SDS. Please be aware, however, that the responsibility for a label or SDS prepared by citing or copying this classification result lies with users.
  • This GHS classification was conducted based on the information sources and the guidance for classification and judgement which are described in the GHS Classification Guidance for the Japanese Government etc. Using other literature, test results etc. as evidence and including different content from this classification result in a label or SDS are allowed.
  • Hazard statement and precautionary statement will show by hovering the mouse cursor over a code in the column of "Hazard statement" and "Precautionary statement," respectively. In the excel file, both the codes and statements are provided.
  • A blank or "-" in the column of "Classification" denotes that a classification for the hazard class was not conducted in the year.

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