Item | Information |
---|---|
CAS RN | 1332-07-6 |
Chemical Name | Zinc borate |
Substance ID | H27-A-022/C-052A_P |
Classification year (FY) | FY2015 |
Ministry who conducted the classification | Ministry of Health, Labour and Welfare (MHLW)/Ministry of the Environment (MOE) |
New/Revised | New |
Classification result in other fiscal year | |
Download of Excel format | Excel file |
Item | Information |
---|---|
Guidance used for the classification (External link) | GHS Classification Guidance for the Japanese Government (FY2013 revised edition (Ver. 1.1)) |
UN GHS document (External link) | UN GHS document |
Definitions/Abbreviations (Excel file) | Definitions/Abbreviations |
Model Label by MHLW (External link) | MHLW Website (in Japanese Only) |
Model SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
OECD/eChemPortal (External link) | eChemPortal |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
1 | Explosives | Not applicable |
- |
- | - | There are no chemical groups present in the molecule associated with explosive properties. |
2 | Flammable gases (including chemically unstable gases) | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
3 | Aerosols | Not applicable |
- |
- | - | Not an aerosol product. |
4 | Oxidizing gases | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
5 | Gases under pressure | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
6 | Flammable liquids | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
7 | Flammable solids | Not classified |
- |
- | - | It is not combustible (HSDB Access on July 2015). |
8 | Self-reactive substances and mixtures | Not applicable |
- |
- | - | There are no chemical groups present in the molecule associated with explosive or self-reactive properties. |
9 | Pyrophoric liquids | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
10 | Pyrophoric solids | Not classified |
- |
- | - | It is not combustible (HSDB Access on July 2015). |
11 | Self-heating substances and mixtures | Not classified |
- |
- | - | It is not combustible (HSDB Access on July 2015). |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified |
- |
- | - | It is estimated that it does not react vigorously with water from water solubility data measured. Water solubility: 3.0g/L (HSDB (Access on July 2015)) |
13 | Oxidizing liquids | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
14 | Oxidizing solids | Classification not possible |
- |
- | - | It is an inorganic compound that contains oxygen, but the classification is not possible due to no data. |
15 | Organic peroxides | Not applicable |
- |
- | - | It is an inorganic compound. |
16 | Corrosive to metals | Classification not possible |
- |
- | - | No established test method suitable for solid substances. |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Not classified |
- |
- | - | From an LD50 value (males) of > 10 g/kg for rats (HSDB (Access on July 2015)), it was classified as "Not classified." |
1 | Acute toxicity (Dermal) | Not classified |
- |
- | - | From an LD50 value (males, females) of > 10 g/kg for rabbits (HSDB (Access on July 2015)), it was classified as "Not classified." |
1 | Acute toxicity (Inhalation: Gases) | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
1 | Acute toxicity (Inhalation: Vapours) | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
2 | Skin corrosion/irritation | Not classified |
- |
- | - | Not irritating with the primary irritation index (PII) of 0 was reported in a skin irritation test using rabbits (HSDB (Access on July 2015), EPA Pesticide Fact Sheet (1991)), and it is reported that in a skin irritation test using guinea pigs, only slight erythema was observed (EPA Science review (1990)). Therefore, the substance was classified as "Not classified" (Category 3 in UN GHS classification). |
3 | Serious eye damage/eye irritation | Category 2 |
Warning |
H319 | P305+P351+P338 P337+P313 P264 P280 |
It is reported that this substance caused irritation with mild conjunctivitis in rabbit eyes (HSDB (Access on July 2015)) and it is written that this substance is irritating to eyes (HSDB (Access on July 2015)). Therefore, the substance was classified in Category 2. |
4 | Respiratory sensitization | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
4 | Skin sensitization | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. Besides, it is reported that in a skin sensitization test using guinea pigs, sensitization by this substance was not observed (HSDB (Access on July 2015), EPA Science review (1990)), but it was considered to be insufficient data to be used for the classification due to unknown details of a test method and so on. |
5 | Germ cell mutagenicity | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. Namely, there are no in vivo data, and as for in vitro, a bacterial reverse mutation test was negative (HSDB (Access on July 2015), EPA Pesticide Fact Sheet (1991)). |
6 | Carcinogenicity | Classification not possible |
- |
- | - | Due to no classification result by the international organization and lack of data, the classification is not possible. |
7 | Reproductive toxicity | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. Besides, for boric acid (CAS: 10043-35-3), decreased fertility in a reproductive toxicity test using rats and mice and fetal toxicity and teratogenesis (head, face, brain, and cardiovascular system) in a developmental toxicity test using rats and rabbits were observed. Therefore, boric acid was classified in Category 1B (2013 GHS Classification Results (NITE Chemical Risk Information Platform (Access on July 2015))). |
8 | Specific target organ toxicity - Single exposure | Classification not possible |
- |
- | - | Because no available data can be used to classify this substance, the classification is not possible due to lack of data. Besides, for boric acid, nausea, vomiting, abdominal pains, diarrhea, central nervous system depression, convulsions, and respiratory irritation were described in humans (ACGIH (7th, 2005), DFGOT vol.5 (1993)), and slight respiratory tract irritation was observed in experimental animals (ECETOC TR63 (1995)). |
9 | Specific target organ toxicity - Repeated exposure | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. Besides, for boric acid (CAS: 10043-35-3), there is no report on effects of repeated exposure in humans. As for experimental animals, it is written that in a 13-week or 2-year diet administration test in mice and rats, effects on testis (atrophy, atrophy of spermatogenic tubules), spleen (increased extramedullary hematopoiesis), and blood system (decreased hemoglobin and hematocrit) were observed at the doses above the range of Category 2 in Guidance values (corresponding to 150 mg/kg/day or higher) (Initial Risk Assessment, NITE (2008)). It corresponds to "Not classified" in an oral route. However, because there is no toxicity information in other routes, boric acid was classified as "Classification not possible" due to lack of data (2013 GHS Classification Results (NITE Chemical Risk Information Platform (Access on July 2015))). |
10 | Aspiration hazard | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Classification not possible |
- |
- | - | The classification is not possible because appropriate data are not obtained. |
11 | Hazardous to the aquatic environment (Long-term) | Classification not possible |
- |
- | - | The classification is not possible because appropriate data are not obtained. |
12 | Hazardous to the ozone layer | Classification not possible |
- |
- | - | No data. |
* A blank or "-" in a cell of classification denotes that the classification of the hazard class was not conducted. * Hazard_statement_and/or_Precautionary_statement will show when hovering the mouse over a code of Hazard_statement_and/or_Precautionary_statement. Hazard_statement_and/or_Precautionary_statement are also provided in the Excel file. * Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. * Codes assigned to each of the hazard statements and codes for each of the precautionary statement are based on the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) in United Nations. |