GHS Classification Result
GENERAL INFORMATION
REFERENCE INFORMATION
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
GENERAL INFORMATION
| Item | Information |
|---|---|
| CAS RN | 12045-78-2 |
| Chemical Name | Potassium tetraborate |
| Substance ID | H27-A-024/C-054A_P |
| Classification year (FY) | FY2015 |
| Ministry who conducted the classification | Ministry of Health, Labour and Welfare (MHLW)/Ministry of the Environment (MOE) |
| New/Revised | New |
| Classification result in other fiscal year | |
| Download of Excel format | Excel file |
REFERENCE INFORMATION
| Item | Information |
|---|---|
| Guidance used for the classification (External link) | GHS Classification Guidance for the Japanese Government (FY2013 revised edition (Ver. 1.1)) |
| UN GHS document (External link) | UN GHS document |
| Definitions/Abbreviations (Excel file) | Definitions/Abbreviations |
| Model Label by MHLW (External link) | MHLW Website (in Japanese Only) |
| Model SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
| OECD/eChemPortal (External link) | eChemPortal |
| Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable |
- |
- | - | There are no chemical groups present in the molecule associated with explosive properties. |
| 2 | Flammable gases (including chemically unstable gases) | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
| 3 | Aerosols | Not applicable |
- |
- | - | Not an aerosol product. |
| 4 | Oxidizing gases | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
| 5 | Gases under pressure | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
| 6 | Flammable liquids | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
| 7 | Flammable solids | Not classified |
- |
- | - | It is not combustible (GESTIS (Access on June2015)). |
| 8 | Self-reactive substances and mixtures | Not applicable |
- |
- | - | There are no chemical groups present in the molecule associated with explosive or self-reactive properties. |
| 9 | Pyrophoric liquids | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
| 10 | Pyrophoric solids | Not classified |
- |
- | - | It is not combustible (GESTIS (Access on June2015)). |
| 11 | Self-heating substances and mixtures | Not classified |
- |
- | - | It is not combustible (GESTIS (Access on June2015)). |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Classification not possible |
- |
- | - | Due to no data, the classification is not possible. |
| 13 | Oxidizing liquids | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
| 14 | Oxidizing solids | Classification not possible |
- |
- | - | It is an inorganic compound that contains oxygen, but the classification is not possible due to no data. |
| 15 | Organic peroxides | Not applicable |
- |
- | - | It is an inorganic compound. |
| 16 | Corrosive to metals | Classification not possible |
- |
- | - | No established test method suitable for solid substances. |
| Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 1 | Acute toxicity (Oral) | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| 1 | Acute toxicity (Dermal) | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| 1 | Acute toxicity (Inhalation: Gases) | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
| 1 | Acute toxicity (Inhalation: Vapours) | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
| 1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| 2 | Skin corrosion/irritation | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. Besides, boric acid was classified in Category 2 because irritation was observed in a skin irritation test using guinea pigs and rabbits (2013 GHS Classification Results (NITE Chemical Risk Information Platform (Access on July 2015))). |
| 3 | Serious eye damage/eye irritation | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. Besides, boric acid was classified in Category 2 because it was reported to be irritating to eyes in rabbits and humans (2013 GHS Classification Results (NITE Chemical Risk Information Platform (Access on July 2015))). |
| 4 | Respiratory sensitization | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| 4 | Skin sensitization | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| 5 | Germ cell mutagenicity | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| 6 | Carcinogenicity | Classification not possible |
- |
- | - | Due to no classification result by other organizations and lack of data, the classification is not possible. |
| 7 | Reproductive toxicity | Classification not possible |
- |
- | - | Because no available data can be used to classify this substance, the classification is not possible due to lack of data. Besides, for boric acid (CAS: 10043-35-3), decreased fertility in a reproductive toxicity test using rats and mice and fetal toxicity and teratogenesis (head, face, brain, and cardiovascular system) in a developmental toxicity test using rats and rabbits were observed. Therefore, boric acid was classified in Category 1B (2013 GHS Classification Results (NITE Chemical Risk Information Platform (Access on July 2015))). |
| 8 | Specific target organ toxicity - Single exposure | Category 3 (Respiratory tract irritation) |
 Warning |
H335 | P304+P340 P403+P233 P261 P271 P312 P405 P501 |
Because no available data can be used to classify this substance, the classification is not possible due to lack of data. However, borate is irritating to the respiratory tract (ACGIH (7th, 2005), HSDB (Access on June 2015)). Therefore, this substance was classified in Category 3 (respiratory tract irritation). Besides, for boric acid, nausea, vomiting, abdominal pains, diarrhea, central nervous system depression, convulsions, and respiratory irritation were described in humans (ACGIH (7th, 2005), DFGOT vol.5 (1993)), and slight respiratory tract irritation was observed in experimental animals (ECETOC TR63 (1995)). |
| 9 | Specific target organ toxicity - Repeated exposure | Classification not possible |
- |
- | - | Because no available data can be used to classify this substance, the classification is not possible due to lack of data. Besides, for boric acid (CAS: 10043-35-3), there is no report on effects of repeated exposure in humans. As for experimental animals, it is described that in a 13-week or 2-year diet administration test in mice and rats, effects on the testis (atrophy, atrophy of spermatogenic tubules), the spleen (increased extramedullary hematopoiesis), and the blood system (decreased hemoglobin and hematocrit) were observed at the doses above the range of Category 2 in Guidance values (corresponding to 150 mg/kg/day or higher) (Initial Risk Assessment, NITE (2008)). From the above information, it corresponds to "Not classified" in an oral route. However, because there is no toxicity information in other routes, boric acid was classified as "Classification not possible" due to lack of data (2013 GHS Classification Results (NITE Chemical Risk Information Platform (Access on July 2015))). |
| 10 | Aspiration hazard | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
| Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment (Acute) | Classification not possible |
- |
- | - | No data. |
| 11 | Hazardous to the aquatic environment (Long-term) | Classification not possible |
- |
- | - | No data. |
| 12 | Hazardous to the ozone layer | Classification not possible |
- |
- | - | No data. |
NOTE:
| * A blank or "-" in a cell of classification denotes that the classification of the hazard class was not conducted. * Hazard_statement_and/or_Precautionary_statement will show when hovering the mouse over a code of Hazard_statement_and/or_Precautionary_statement. Hazard_statement_and/or_Precautionary_statement are also provided in the Excel file. * Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. * Codes assigned to each of the hazard statements and codes for each of the precautionary statement are based on the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) in United Nations. |