Item | Information |
---|---|
CAS RN | 10026-11-6 |
Chemical Name | Zirconium tetrachloride |
Substance ID | H27-A-046/C-120A_P |
Classification year (FY) | FY2015 |
Ministry who conducted the classification | Ministry of Health, Labour and Welfare (MHLW)/Ministry of the Environment (MOE) |
New/Revised | New |
Classification result in other fiscal year | |
Download of Excel format | Excel file |
Item | Information |
---|---|
Guidance used for the classification (External link) | GHS Classification Guidance for the Japanese Government (FY2013 revised edition (Ver. 1.1)) |
UN GHS document (External link) | UN GHS document |
Definitions/Abbreviations (Excel file) | Definitions/Abbreviations |
Model Label by MHLW (External link) | MHLW Website (in Japanese Only) |
Model SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
OECD/eChemPortal (External link) | eChemPortal |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
1 | Explosives | Not applicable |
- |
- | - | There are no chemical groups present in the molecule associated with explosive properties. |
2 | Flammable gases (including chemically unstable gases) | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
3 | Aerosols | Not applicable |
- |
- | - | Not an aerosol product. |
4 | Oxidizing gases | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
5 | Gases under pressure | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
6 | Flammable liquids | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
7 | Flammable solids | Classification not possible |
- |
- | - | Due to no data, the classification is not possible. |
8 | Self-reactive substances and mixtures | Not applicable |
- |
- | - | There are no chemical groups present in the molecule associated with explosive or self-reactive properties. |
9 | Pyrophoric liquids | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
10 | Pyrophoric solids | Classification not possible |
- |
- | - | Due to no data, the classification is not possible. |
11 | Self-heating substances and mixtures | Classification not possible |
- |
- | - | Due to no data, the classification is not possible. |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Classification not possible |
- |
- | - | Because there is the observation result that it reacts with water and decompose (HSDB (Access on September 2015)), it is estimated that it reacts with water, but the classification is not possible due to no data. |
13 | Oxidizing liquids | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
14 | Oxidizing solids | Classification not possible |
- |
- | - | It is an inorganic compound that contains halogen, but the classification is not possible due to no data. |
15 | Organic peroxides | Not applicable |
- |
- | - | It is an inorganic compound. |
16 | Corrosive to metals | Classification not possible |
- |
- | - | No established test method suitable for solid substances. |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Category 4 |
Warning |
H302 | P301+P312 P264 P270 P330 P501 |
From a reported LD50 value of 1,690 mg/kg for rats (ACGIH (7th, 2001)), it was classified in Category 4. |
1 | Acute toxicity (Dermal) | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
1 | Acute toxicity (Inhalation: Gases) | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
1 | Acute toxicity (Inhalation: Vapours) | Not applicable |
- |
- | - | "Solids" according to GHS definition. |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
2 | Skin corrosion/irritation | Category 2 |
Warning |
H315 | P302+P352 P332+P313 P362+P364 P264 P280 P321 |
From the information that this substance is irritating to skin (HSDB (Access on September 2015)), it was classified in Category 2. |
3 | Serious eye damage/eye irritation | Category 2 |
Warning |
H319 | P305+P351+P338 P337+P313 P264 P280 |
From the information that this substance is irritating to eyes (HSDB (Access on September 2015)), it was classified in Category 2. Besides, it is written that exposure to this substance possibly causes severe eye irritation (HSDB (Access on September 2015)). |
4 | Respiratory sensitization | Classification not possible |
- |
- | - | The classification is not possible due to lack of data. Besides, in DFGOT vol. 12 (1999), zirconium and its compounds were classified as a respiratory sensitizer. However, due to impossible to judge if applicable to this substance or not, it was classified as "Classification not possible." |
4 | Skin sensitization | Classification not possible |
- |
- | - | In DFGOT vol. 12 (1999), zirconium compounds including this substance were classified as a sensitizer (Sah) on the basis of information on other zirconium compounds (DFGOT vol. 12 (1999)). On the other hand, it is reported that this substance was not sensitizing in a modified maximization test using guinea pigs (DFGOT vol. 12 (1999)), and a local lymph node test using mice was negative (DFGOT vol. 12 (1999)), but details are unknown. Furthermore, it is written in PATTY (6th, 2012) that this substance has a low sensitization potential among zirconium compounds and does not cause sensitization in animals (PATTY (6th, 2012)). From the above, the substance was classified as "Classification not possible." |
5 | Germ cell mutagenicity | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
6 | Carcinogenicity | Classification not possible |
- |
- | - | As described in this hazard class for zirconium (CAS number: 7440-67-7), ACGIH classified zirconium and its compounds in A4 in carcinogenicity (ACGIH (7th, 2001)). Therefore, this substance was classified as "Classification not possible" for this hazard class. |
7 | Reproductive toxicity | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
8 | Specific target organ toxicity - Single exposure | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
9 | Specific target organ toxicity - Repeated exposure | Classification not possible |
- |
- | - | The classification is not possible due to lack of data. Besides, in 22 workers exposed to the fume of zirconium (zirconium chloride, zirconium oxide, and metallic zirconium) in refining and reduction processes for one to five years (exposure levels not specified), no lung granuloma was observed. However, mild bronchial asthma in two and chronic bronchitis in five were found. However, it is reported that some of them were also exposed to chlorine (DFGOT vol. 12 (1999), Reed (1956): quoted in DFGOT vol.12 (1999)), and from the information, there is the comment in ACGIH (7th, 2001) and PATTY (6th, 2012) that (noted) abnormality related to zirconium was not observed. |
10 | Aspiration hazard | Classification not possible |
- |
- | - | Due to lack of data, the classification is not possible. |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Category 3 |
- |
H402 | P273 P501 |
From 96-hour LC50 = 20000 micro g Zr/L for fish (Oncorhynchus mykiss) (a converted value: 51 mg ZrCl4/L) (Couture et al., 1989), it was classified in Category 3. |
11 | Hazardous to the aquatic environment (Long-term) | Classification not possible |
- |
- | - | The classification is not possible because appropriate data are not obtained. It was classified in Category 3 for acute toxicity, but it is thought that regarding the data in Oncorhynchus mykiss which is evidence for the category, its toxic effects are considered to be caused by low pH (Couture et al., 1989), therefore, it is not used as the basis for classification in a chronic toxicity. |
12 | Hazardous to the ozone layer | Classification not possible |
- |
- | - | No data. |
* A blank or "-" in a cell of classification denotes that the classification of the hazard class was not conducted. * Hazard_statement_and/or_Precautionary_statement will show when hovering the mouse over a code of Hazard_statement_and/or_Precautionary_statement. Hazard_statement_and/or_Precautionary_statement are also provided in the Excel file. * Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. * Codes assigned to each of the hazard statements and codes for each of the precautionary statement are based on the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) in United Nations. |