GHS Classification Result
GENERAL INFORMATION
REFERENCE INFORMATION
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
GENERAL INFORMATION
| Item | Information |
|---|---|
| CAS RN | 7440-33-7 |
| Chemical Name | Tungsten |
| Substance ID | H27-B-076/C-124B_P |
| Classification year (FY) | FY2015 |
| Ministry who conducted the classification | Ministry of Health, Labour and Welfare (MHLW)/Ministry of the Environment (MOE) |
| New/Revised | Revised |
| Classification result in other fiscal year | FY2006 |
| Download of Excel format | Excel file |
REFERENCE INFORMATION
| Item | Information |
|---|---|
| Guidance used for the classification (External link) | GHS Classification Guidance for the Japanese Government (FY2013 revised edition (Ver. 1.1)) |
| UN GHS document (External link) | UN GHS document |
| Definitions/Abbreviations (Excel file) | Definitions/Abbreviations |
| Model Label by MHLW (External link) | MHLW Website (in Japanese Only) |
| Model SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
| OECD/eChemPortal (External link) | eChemPortal |
| Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable |
- |
- | - | There are no chemical groups associated with explosive properties present in the molecule. |
| 2 | Flammable gases (including chemically unstable gases) | Not applicable |
- |
- | - | Solid (GHS definition). |
| 3 | Aerosols | Not applicable |
- |
- | - | Not aerosol products. |
| 4 | Oxidizing gases | Not applicable |
- |
- | - | Solid (GHS definition). |
| 5 | Gases under pressure | Not applicable |
- |
- | - | Solid (GHS definition). |
| 6 | Flammable liquids | Not applicable |
- |
- | - | Solid (GHS definition). |
| 7 | Flammable solids | Classification not possible |
- |
- | - | No data available. Besides, there is the information that a powder can be pyrophoric (HSDB (Access on September 2015)), but the metal is non-flammable in compact form (GESTIS (Access on September 2015)). |
| 8 | Self-reactive substances and mixtures | Not applicable |
- |
- | - | There are no chemical groups present in the molecule associated with explosive or self-reactive properties. |
| 9 | Pyrophoric liquids | Not applicable |
- |
- | - | Solid (GHS definition). |
| 10 | Pyrophoric solids | Classification not possible |
- |
- | - | No data available. Besides, there is the information that a powder can be pyrophoric (HSDB (Access on September 2015)), but the metal is non-flammable in compact form (GESTIS (Access on September 2015)). |
| 11 | Self-heating substances and mixtures | Classification not possible |
- |
- | - | No data available. |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified |
- |
- | - | It is estimated that it does not react vigorously with water from the observation result that it is insoluble in water (ICSC (2001)). |
| 13 | Oxidizing liquids | Not applicable |
- |
- | - | Solid (GHS definition). |
| 14 | Oxidizing solids | Not applicable |
- |
- | - | It is an inorganic substance not containing oxygen or halogen. |
| 15 | Organic peroxides | Not applicable |
- |
- | - | It is an inorganic substance. |
| 16 | Corrosive to metals | Classification not possible |
- |
- | - | Test methods applicable to solid substances are not available. |
| Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 1 | Acute toxicity (Oral) | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
| 1 | Acute toxicity (Dermal) | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
| 1 | Acute toxicity (Inhalation: Gases) | Not applicable |
- |
- | - | Solid (GHS definition) |
| 1 | Acute toxicity (Inhalation: Vapours) | Not applicable |
- |
- | - | Solid (GHS definition) |
| 1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
| 2 | Skin corrosion/irritation | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
| 3 | Serious eye damage/eye irritation | Category 2B |
Warning |
H320 | P305+P351+P338 P337+P313 P264 |
There is a report that in an eye irritation test with rabbits, as a result of an application of 100 mg of this substance, mild conjunctival irritation was observed (ATSDR (2005), PATTY (6th, 2012)). From the above, it was classified in Category 2B. |
| 4 | Respiratory sensitization | Classification not possible |
- |
- | - | Classification not possible due to lack of data. Besides, among workers exposed to hard alloy dust, asthma caused by this substance was reported (PATTY (6th, 2012)). |
| 4 | Skin sensitization | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
| 5 | Germ cell mutagenicity | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
| 6 | Carcinogenicity | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
| 7 | Reproductive toxicity | Classification not possible |
- |
- | - | There is no information on reproductive effects of this substance. Therefore, classification is not possible due to lack of data. Besides, as for soluble sodium tungstate (CAS RN: 13472-45-2), as a result of a reproductive toxicity test with rats by the oral route, no adverse effect on fertility and sexual function was indicated, however, since there is not enough information for evaluation of developmental toxicity effects, it was classified as "Classification not possible" due to lack of data (please refer to this hazard class of sodium tungstate). |
| 8 | Specific target organ toxicity - Single exposure | Category 3 (Respiratory tract irritation) |
 Warning |
H335 | P304+P340 P403+P233 P261 P271 P312 P405 P501 |
This substance is irritating to the respiratory tract (ACGIH (7th, 2001)). As for humans, there is one case of accidental drinking of a mixture containing this substance (ACGIH (7th, 2001), PATTY (6th, 2012), ATSDR (2005)). However, it could not be used for classification since it was not possible to judge if the symptoms were due to only this substance. As for experimental animals, in a test where guinea pigs were orally dosed (780 mg/kg or more), anorexia, coordination ataxia, tremor and dyspnea were observed (ACGIH (7th, 2001), DFGOT vol. 23 (2007), ATSDR (2005)), however, since it was a very old report from 1924, and there was no follow-up data for these findings, they were not adopted. From the above, it was classified in Category 3 (respiratory tract irritation). |
| 9 | Specific target organ toxicity - Repeated exposure | Classification not possible |
- |
- | - | Classification not possible due to lack of data. In humans, there is a report that among workers who had been exposed for a long term in 3 factories in which the average tungsten concentrations were 6 mg/m3 or less and the highest concentration was 36.9 mg/m3, irritation of the nose or skin was observed, but no effects on pulmonary functions nor pneumoconiosis were found (DFGOT vol. 23 (2007)). Also, there is a report that on examination of workers occupationally exposed at tungsten concentrations of 5 mg/m3 or less for a long term, no pneumoconiosis was observed in exposure to tungsten or insoluble tungsten compounds alone (ACGIH (7th, 2001)). On the other hand, there is a report that pulmonary fibrosis was found in 9-10% of employees exposed to only tungsten (ACGIH (7th, 2001)). As for experimental animals, there is a report that in a test where guinea pigs were dosed intratracheally at 50 mg/week for 3 weeks, relatively inert though, interstitial cellular proliferation was observed in the lung, and even after one year, the effect persisted (DFGOT vol. 23 (2007), ACGIH (7th, 2001)). As above, there is no consistency in effects on the human respiratory system, and there is no data on experimental animals which are available for classification. Therefore, it was classified as "Classification not possible" due to lack of data. |
| 10 | Aspiration hazard | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
| Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment (Acute) | Classification not possible |
- |
- | - | No data available. |
| 11 | Hazardous to the aquatic environment (Long-term) | Classification not possible |
- |
- | - | No data available. |
| 12 | Hazardous to the ozone layer | Classification not possible |
- |
- | - | No data available. |
NOTE:
| * A blank or "-" in a cell of classification denotes that the classification of the hazard class was not conducted. * Hazard_statement_and/or_Precautionary_statement will show when hovering the mouse over a code of Hazard_statement_and/or_Precautionary_statement. Hazard_statement_and/or_Precautionary_statement are also provided in the Excel file. * Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. * Codes assigned to each of the hazard statements and codes for each of the precautionary statement are based on the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) in United Nations. |