Item | Information |
---|---|
CAS RN | 1305-78-8 |
Chemical Name | Quicklime [Calcium oxide] |
Substance ID | H28-B-011, C-014B |
Classification year (FY) | FY2016 |
Ministry who conducted the classification | Ministry of Health, Labour and Welfare (MHLW)/Ministry of the Environment (MOE) |
New/Revised | Revised |
Classification result in other fiscal year | FY2006 |
Download of Excel format | Excel file |
Item | Information |
---|---|
Guidance used for the classification (External link) | GHS Classification Guidance for the Japanese Government (FY2013 revised edition (Ver. 1.1)) |
UN GHS document (External link) | UN GHS document |
Definitions/Abbreviations (Excel file) | Definitions/Abbreviations |
Model Label by MHLW (External link) | MHLW Website (in Japanese Only) |
Model SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
OECD/eChemPortal (External link) | eChemPortal |
Hazard class | Classification |
Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
1 | Explosives | Not applicable |
- |
- | - | There are no chemical groups associated with explosive properties present in the molecule. |
2 | Flammable gases (including chemically unstable gases) | Not applicable |
- |
- | - | Solid (GHS definition). |
3 | Aerosols | Not applicable |
- |
- | - | Not aerosol products. |
4 | Oxidizing gases | Not applicable |
- |
- | - | Solid (GHS definition). |
5 | Gases under pressure | Not applicable |
- |
- | - | Solid (GHS definition). |
6 | Flammable liquids | Not applicable |
- |
- | - | Solid (GHS definition). |
7 | Flammable solids | Not classified |
- |
- | - | It is not combustible (ICSC (1997)). |
8 | Self-reactive substances and mixtures | Not applicable |
- |
- | - | There are no chemical groups present in the molecule associated with explosive or self-reactive properties. |
9 | Pyrophoric liquids | Not applicable |
- |
- | - | Solid (GHS definition). |
10 | Pyrophoric solids | Not classified |
- |
- | - | It is not combustible (ICSC (1997)). |
11 | Self-heating substances and mixtures | Not classified |
- |
- | - | It is not combustible (ICSC (1997)). |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified |
- |
- | - | It reacts vigorously with water, however, because the product is potassium hydroxide, which is not combustible (ICSC (1997)), it was classified as "Not classified." |
13 | Oxidizing liquids | Not applicable |
- |
- | - | Solid (GHS definition). |
14 | Oxidizing solids | Classification not possible |
- |
- | - | It is an inorganic compound containing oxygen, but the classification is not possible due to no data. |
15 | Organic peroxides | Not applicable |
- |
- | - | It is an inorganic compound. |
16 | Corrosive to metals | Classification not possible |
- |
- | - | Because test methods applicable to solid substances are not available, the classification is not possible. Besides, it is classified in Class 8, PG III (UN1910) in UNRTDG. |
Hazard class | Classification |
Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Not classified |
- |
- | - | Based on the LD50 values of 5,000 mg/kg and 5,916 mg/kg for rats (Risk Assessment Report (Food Additives) (Food Safety Commission of Japan, 2013)), the substance was classified as "Not classified" (Category 5 in UN GHS classification). |
1 | Acute toxicity (Dermal) | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
1 | Acute toxicity (Inhalation: Gases) | Not applicable |
- |
- | - | Solid (GHS definition) |
1 | Acute toxicity (Inhalation: Vapours) | Not applicable |
- |
- | - | Solid (GHS definition) |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
2 | Skin corrosion/irritation | Category 2 |
Warning |
H315 |
P302+P352
P332+P313 P362+P364 P264 P280 P321 |
Based on the description that this substance is very irritating to moist skin (ACGIH (7th, 2001)), the substance was classified in Category 2. Besides, it is classified as Class 8 in the United Nations Recommendations on the Transport of Dangerous Goods. The classification was changed with a revision of the GHS classification guidance for the Japanese Government. |
3 | Serious eye damage/eye irritation | Category 1 |
Danger |
H318 |
P305+P351+P338
P280 P310 |
Based on the description that particles of calcium oxide can cause severe burns to the eye (ACGIH (7th, 2001)), the substance was classified in Category 1. |
4 | Respiratory sensitization | Classification not possible |
- |
- | - | No data available. |
4 | Skin sensitization | Classification not possible |
- |
- | - | No data available. |
5 | Germ cell mutagenicity | Classification not possible |
- |
- | - |
Classification not possible due to lack of data. No in vivo data are available. As for in vitro data, the result of a bacterial reverse mutation test was negative (Risk Assessment Report (Food Additives) (Food Safety Commission of Japan, 2013)). |
6 | Carcinogenicity | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
7 | Reproductive toxicity | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
8 | Specific target organ toxicity - Single exposure | Category 1 (respiratory organs) |
Danger |
H370 |
P308+P311
P260 P264 P270 P321 P405 P501 |
This substance reacts with water to form calcium hydroxide. It is described that for humans, pulmonary edema and shock are caused by short exposure to a large amount of calcium hydroxide (PATTY (4th, 1993)). From the above, the substance was classified in Category 1 (respiratory organs). Besides, in the previous classification, this substance was classified in Category 2 (systemic toxicity, digestive system), based on the description in HSDB that when this substance is accidentally swallowed, the pulse and respiration become faster, the body temperature drops, glottic edema causes dyspnea and shock, and esophageal and gastric perforation occurs. However, this information cannot be found in current HSDB (Last Revision Date: September 4th, 2014), and it is thought that esophageal and gastric perforation was caused by the corrosive effects of this substance. Therefore, the classification was revised. |
9 | Specific target organ toxicity - Repeated exposure | Category 1 (respiratory organs) |
Danger |
H372 |
P260
P264 P270 P314 P501 |
It is reported that inflammation of the respiratory passages and ulceration and perforation of the nasal septum are caused by inhalation of lime in humans (ACGIH (7th, 2001)). Therefore, the substance was classified in Category 1 (respiratory organs). |
10 | Aspiration hazard | Classification not possible |
- |
- | - |
Classification not possible due to lack of data. Besides, in the previous classification, it was classified in Category 1 based on the description in HSDB that "aspiration pneumonia" was observed in humans. However, it was considered that this description was an error in the writing of the information in HSDB that "pneumonia" resulted from "inhalation" of calcium oxide dust in humans (HSDB (Access on May 2016)). |
Hazard class | Classification |
Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Classification not possible |
- |
- | - | No data available. |
11 | Hazardous to the aquatic environment (Long-term) | Classification not possible |
- |
- | - | No data available. |
12 | Hazardous to the ozone layer | Classification not possible |
- |
- | - | No data available. |
* A blank or "-" in a cell of classification denotes that the classification of the hazard class was not conducted. * Hazard_statement_and/or_Precautionary_statement will show when hovering the mouse over a code of Hazard_statement_and/or_Precautionary_statement. Hazard_statement_and/or_Precautionary_statement are also provided in the Excel file. * Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. * Codes assigned to each of the hazard statements and codes for each of the precautionary statement are based on the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) in United Nations. |