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GHS Classification Result

GENERAL INFORMATION

Item	Information
CAS RN	79-47-0
Chemical Name	3-Chloropentafluoro-1-propene
Substance ID	H29-A-001
Classification year (FY)	FY2017
Ministry who conducted the classification	Ministry of Health, Labour and Welfare (MHLW)/Ministry of the Environment (MOE)
New/Revised	New
Classification result in other fiscal year
Download of Excel format	Excel file

REFERENCE INFORMATION

Item	Information
Guidance used for the classification (External link)	GHS Classification Guidance for the Japanese Government (FY2013 revised edition (Ver. 1.1))
UN GHS document (External link)	UN GHS document
Definitions/Abbreviations (Excel file)	Definitions/Abbreviations
Model Label by MHLW (External link)
Model SDS by MHLW (External link)
OECD/eChemPortal (External link)	eChemPortal

PHYSICAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification
1	Explosives	Not applicable	- -	-	-	Gas (GHS definition)
2	Flammable gases (including chemically unstable gases)	Classification not possible	- -	-	-	No data available.
3	Aerosols	Not applicable	- -	-	-	Not aerosol products.
4	Oxidizing gases	Classification not possible	- -	-	-	No data available.
5	Gases under pressure	Classification not possible	- -	-	-	No data available.
6	Flammable liquids	Not applicable	- -	-	-	Gas (GHS definition)
7	Flammable solids	Not applicable	- -	-	-	Gas (GHS definition)
8	Self-reactive substances and mixtures	Not applicable	- -	-	-	Gas (GHS definition)
9	Pyrophoric liquids	Not applicable	- -	-	-	Gas (GHS definition)
10	Pyrophoric solids	Not applicable	- -	-	-	Gas (GHS definition)
11	Self-heating substances and mixtures	Not applicable	- -	-	-	Gas (GHS definition)
12	Substances and mixtures which, in contact with water, emit flammable gases	Not applicable	- -	-	-	Gas (GHS definition)
13	Oxidizing liquids	Not applicable	- -	-	-	Gas (GHS definition)
14	Oxidizing solids	Not applicable	- -	-	-	Gas (GHS definition)
15	Organic peroxides	Not applicable	- -	-	-	Gas (GHS definition)
16	Corrosive to metals	Classification not possible	- -	-	-	Test methods applicable to gas substances are not available.

HEALTH HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification
1	Acute toxicity (Oral)	Not applicable	- -	-	-	Gas (GHS definition)
1	Acute toxicity (Dermal)	Not applicable	- -	-	-	Gas (GHS definition)
1	Acute toxicity (Inhalation: Gases)	Classification not possible	- -	-	-	Classification not possible due to lack of data. Although it is described that the lethal concentration in experimental animals is approximately 27 ppm (Director Notice, No. 0727001, July 27, 2011, Chemical Hazards Control Division, Industrial Safety and Health Department, Labour Standards Bureau, Ministry of Health, Labor and Welfare; Source: Abstracts of the 1984 Annual Meeting, E. F. Stula, The Toxicologist Vol. 4, p. 66, 1984), this was not adopted as evidence to classify this substance in Category 1 as the exposure period was unknown. Besides, it is stated in the above notice by the Ministry of Health, Labor and Welfare that it is important to ensure that measures are implemented to prevent workers handling this substance from their being exposed to it for the following reasons: this substance has a low boiling point of approximately 8 deg C and is highly volatile; the substance is a highly toxic gas with a lethal concentration of approximately 27 ppm; and it is pointed out in some literature that significant effects on the lung occurred after exposure to the substance at 5.4 ppm in a subchronic toxicity test with male rats.
1	Acute toxicity (Inhalation: Vapours)	Not applicable	- -	-	-	Gas (GHS definition)
1	Acute toxicity (Inhalation: Dusts and mists)	Not applicable	- -	-	-	Gas (GHS definition)
2	Skin corrosion/irritation	Classification not possible	- -	-	-	Classification not possible due to lack of data.
3	Serious eye damage/eye irritation	Classification not possible	- -	-	-	Classification not possible due to lack of data.
4	Respiratory sensitization	Classification not possible	- -	-	-	Classification not possible due to lack of data.
4	Skin sensitization	Classification not possible	- -	-	-	Classification not possible due to lack of data.
5	Germ cell mutagenicity	Classification not possible	- -	-	-	Classification not possible due to lack of data.
6	Carcinogenicity	Classification not possible	- -	-	-	Classification not possible due to lack of data.
7	Reproductive toxicity	Classification not possible	- -	-	-	Classification not possible due to lack of data.
8	Specific target organ toxicity - Single exposure	Category 1 (respiratory organs)	Danger	H370	P308+P311 P260 P264 P270 P321 P405 P501	As for humans, a case involving acute inhalation exposure was reported in a male worker handling this substance at a chemical factory (Director Notice, No. 0727001, July 27, 2011, Chemical Hazards Control Division, Industrial Safety and Health Department, Labour Standards Bureau, Ministry of Health, Labor and Welfare). According to the research article in which the details were reported, the patient complained of a fever and shortness of breath before being admitted to a hospital approximately 24 hours after exposure. Two days after admission, this substance was detected in the blood and urine. The patient subsequently developed acute lung injury with severe pneumothorax and died 16 days later (Morita S. et al.; BMJ Case Rep 2013. doi:10.1136/bcr-2013-201089). In another case report, it was reported that a worker who was involved in the cleaning of a tank containing this substance complained of coughs, dyspnea, and fever before being admitted to a hospital; subsequently suffered from pulmonary infiltration and pneumothorax and died 16 days later (Thun M. et al., Clin. Toxicol., 1981, 18: 481-487; cited in the aforementioned notice by the Ministry of Health, Labor and Welfare). The information source is not listed in the GHS Classification Guidance for the Japanese government. However, based on the above two case reports, this substance was classified in Category 1 (respiratory organs).
9	Specific target organ toxicity - Repeated exposure	Classification not possible	- -	-	-	Classification not possible due to lack of data.
10	Aspiration hazard	Not applicable	- -	-	-	Gas (GHS definition)

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification
11	Hazardous to the aquatic environment (Acute)	Classification not possible	- -	-	-	No data available.
11	Hazardous to the aquatic environment (Long-term)	Classification not possible	- -	-	-	No data available.
12	Hazardous to the ozone layer	Classification not possible	- -	-	-	No data available.

NOTE:

* A blank or "-" in a cell of classification denotes that the classification of the hazard class was not conducted.
* Hazard_statement_and/or_Precautionary_statement will show when hovering the mouse over a code of Hazard_statement_and/or_Precautionary_statement.
Hazard_statement_and/or_Precautionary_statement are also provided in the Excel file.
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government,
and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.
* Codes assigned to each of the hazard statements and codes for each of the precautionary statement are
based on the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) in United Nations.

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