GHS Classification Result

日本語で表示



GENERAL INFORMATION
Item Information
CAS RN 25134-01-4
Chemical Name Phenol, 2,6-dimethyl-, homopolymer
Substance ID H29-A-003
Classification year (FY) FY2017
Ministry who conducted the classification Ministry of Health, Labour and Welfare (MHLW)/Ministry of the Environment (MOE)
New/Revised New
Classification result in other fiscal year  
Download of Excel format Excel file

REFERENCE INFORMATION
Item Information
Guidance used for the classification (External link) GHS Classification Guidance for the Japanese Government (FY2013 revised edition (Ver. 1.1))
UN GHS document (External link) UN GHS document
Definitions/Abbreviations (Excel file) Definitions/Abbreviations
Model Label by MHLW (External link)  
Model SDS by MHLW (External link)  
OECD/eChemPortal (External link) eChemPortal

PHYSICAL HAZARDS
Hazard class Classification Pictogram
Signal word
Hazard statement
(code)
Precautionary statement
(code)
Rationale for the classification
1 Explosives Not applicable
-
-
- - There are no chemical groups associated with explosive properties present in the molecule.
2 Flammable gases (including chemically unstable gases) Not applicable
-
-
- - Solid (GHS definition).
3 Aerosols Not applicable
-
-
- - Not aerosol products.
4 Oxidizing gases Not applicable
-
-
- - Solid (GHS definition).
5 Gases under pressure Not applicable
-
-
- - Solid (GHS definition).
6 Flammable liquids Not applicable
-
-
- - Solid (GHS definition).
7 Flammable solids Classification not possible
-
-
- - No data available.
8 Self-reactive substances and mixtures Not applicable
-
-
- - There are no chemical groups present in the molecule associated with explosive or self-reactive properties.
9 Pyrophoric liquids Not applicable
-
-
- - Solid (GHS definition).
10 Pyrophoric solids Classification not possible
-
-
- - No data available.
11 Self-heating substances and mixtures Classification not possible
-
-
- - No data available.
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable
-
-
- - The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13 Oxidizing liquids Not applicable
-
-
- - Solid (GHS definition).
14 Oxidizing solids Not applicable
-
-
- - The substance is an organic compound containing oxygen (but not fluorine or chlorine) which is chemically bonded only to carbon or hydrogen.
15 Organic peroxides Not applicable
-
-
- - Organic compounds containing no bivalent -O-O- structure in the molecule.
16 Corrosive to metals Classification not possible
-
-
- - Test methods applicable to solid substances are not available.

HEALTH HAZARDS
Hazard class Classification Pictogram
Signal word
Hazard statement
(code)
Precautionary statement
(code)
Rationale for the classification
1 Acute toxicity (Oral) Not classified
-
-
- - Based on a report of an LD50 value of > 5,000 mg/kg for rats (PATTY (6th, 2012)), this substance was classified as "Not classified."
1 Acute toxicity (Dermal) Classification not possible
-
-
- - Classification not possible due to lack of data.
1 Acute toxicity (Inhalation: Gases) Not applicable
-
-
- - Solid (GHS definition)
1 Acute toxicity (Inhalation: Vapours) Not applicable
-
-
- - Solid (GHS definition)
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible
-
-
- - Classification not possible due to lack of data.
2 Skin corrosion/irritation Classification not possible
-
-
- - Classification not possible due to lack of data. Besides, it is described that this substance was not irritating when applied for four hours in a skin irritation test with rabbits (PATTY (6th, 2012)). However, as the details were unknown, irritation potential could not be denied on the basis of this description alone. Therefore, this substance was classified as "Classification not possible."
3 Serious eye damage/eye irritation Category 2B
-
Warning
H320 P305+P351+P338
P337+P313
P264
It is described that, in an eye irritation test with rabbits, reddening and chemosis of the conjunctivae were observed within 1 hour after an application of this substance, but they resolved within 48 hours (PATTY (6th, 2012)). Therefore, this substance was classified in Category 2B.
4 Respiratory sensitization Classification not possible
-
-
- - Classification not possible due to lack of data.
4 Skin sensitization Classification not possible
-
-
- - Classification not possible due to lack of data. It is described that, in a skin sensitization test with guinea pigs, this substance did not cause delayed hypersensitivity as a result of challenge two weeks after a weekly 6-hour application of this substance to the skin (PATTY (6th, 2012)). However, this information was insufficient to evaluate skin sensitization potential. Therefore, this substance was classified as "Classification not possible."
5 Germ cell mutagenicity Classification not possible
-
-
- - Classification not possible due to lack of data.
6 Carcinogenicity Classification not possible
-
-
- - Classification not possible due to lack of data.
7 Reproductive toxicity Classification not possible
-
-
- - Classification not possible due to lack of data.
8 Specific target organ toxicity - Single exposure Category 3 (Respiratory tract irritation)


Warning
H335 P304+P340
P403+P233
P261
P271
P312
P405
P501
There is no single exposure data on this substance in humans. As for experimental animals, it was reported that signs of nasal irritation were observed in rats exposed by inhalation to the fumes of this substance (concentration not specified) for six hours, but they disappeared shortly after exposure, and there were no deaths or no abnormal findings at necropsy (PATTY (6th, 2012)). Therefore, this substance was classified in Category 3 (respiratory tract irritation).
9 Specific target organ toxicity - Repeated exposure Category 2 (respiratory organs)


Warning
H373 P260
P314
P501
There were no reports on the effects of this substance in humans. Besides, a cross-sectional study to evaluate respiratory symptoms in 227 workers at a plastic-products facility was conducted. Eye, nose, and throat irritation; cough; and wheezing were observed in workers in the injection-molding department, in which this substance was used together with a foaming agent, azodicarbonamide (including 1,1'-azobisformamide). These symptoms were considered to be due to azodicarbonamide blended (PATTY (6th, 2012)).
As for experimental animals, in a 13-week inhalation toxicity study with rats (6 hours/day, 5 days/week), increases in absolute and relative lung weights, mild acute/chronic pulmonary inflammation, and thymic/peribronchial lymph-node histiocytosis were observed at 50 mg/m3 (converted guidance value: 0.036 mg/L), which is within the guidance value range for Category 2 (for dusts) (PATTY (6th, 2012)). Besides, in the oral route, no effects were observed either in a 22-month toxicity study with rats dosed in the diet at up to 10% (converted guidance value: 5,000 mg/kg/day), which exceeds the guidance value range for Category 2, or in a 2-year toxicity study with dogs dosed in the diet at up to 10% (converted guidance value: 2,500 mg/kg/day), which exceeds the guidance value range for Category 2 (PATTY (6th, 2012)).
From the above, this substance was classified in Category 2 (respiratory organs) based on the inhalation data in the experimental animals.
10 Aspiration hazard Classification not possible
-
-
- - Classification not possible due to lack of data.

ENVIRONMENTAL HAZARDS
Hazard class Classification Pictogram
Signal word
Hazard statement
(code)
Precautionary statement
(code)
Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Classification not possible
-
-
- - No data available.
11 Hazardous to the aquatic environment (Long-term) Classification not possible
-
-
- - No data available.
12 Hazardous to the ozone layer Classification not possible
-
-
- - No data available.


NOTE:
* A blank or "-" in a cell of classification denotes that the classification of the hazard class was not conducted.
* Hazard_statement_and/or_Precautionary_statement will show when hovering the mouse over a code of Hazard_statement_and/or_Precautionary_statement.
Hazard_statement_and/or_Precautionary_statement are also provided in the Excel file.
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government,
and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.
* Codes assigned to each of the hazard statements and codes for each of the precautionary statement are
based on the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) in United Nations.

To GHS Information