GHS Classification Results by the Japanese Government

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GENERAL INFORMATION
Item Information
CAS RN 1313-82-2
Chemical Name Disodium sulfide
Substance ID R01-B-033
Classification year (FY) FY2019
Ministry who conducted the classification Ministry of Health, Labour and Welfare (MHLW)/Ministry of the Environment (MOE)
New/Revised Revised
Classification result in other fiscal year FY2006  
Download of Excel format Excel file

REFERENCE INFORMATION
Item Information
Guidance used for the classification (External link) GHS Classification Guidance for the Japanese Government (FY2013 revised edition (Ver. 1.1))
UN GHS document (External link) UN GHS document
Definitions/Abbreviations (Excel file) Definitions/Abbreviations
Model Label by MHLW (External link) MHLW Website (in Japanese Only)
Model SDS by MHLW (External link) MHLW Website (in Japanese Only)
OECD/eChemPortal (External link) eChemPortal

PHYSICAL HAZARDS
Hazard class Classification Pictogram
Signal word
Hazard statement
(code)
Precautionary statement
(code)
Rationale for the classification
1 Explosives *
-
-
- - There are no chemical groups associated with explosive properties present in the molecule. It was classified as "Not classified (Not applicable)."
2 Flammable gases *
-
-
- - Solid (GHS definition). It was classified as "Not classified (Not applicable)."
3 Aerosols *
-
-
- - Not aerosol products. It was classified as "Not classified (Not applicable)."
4 Oxidizing gases *
-
-
- - Solid (GHS definition). It was classified as "Not classified (Not applicable)."
5 Gases under pressure *
-
-
- - Solid (GHS definition). It was classified as "Not classified (Not applicable)."
6 Flammable liquids *
-
-
- - Solid (GHS definition). It was classified as "Not classified (Not applicable)."
7 Flammable solids *
-
-
- - No data available.
8 Self-reactive substances and mixtures *
-
-
- - There are no chemical groups associated with explosive or self-reactive properties present in the molecule. It was classified as "Not classified (Not applicable)."
9 Pyrophoric liquids *
-
-
- - Solid (GHS definition). It was classified as "Not classified (Not applicable)."
10 Pyrophoric solids *
-
-
- - It was classified as "Not classified" because it is classified in Division 4.2, PG II in UNRTDG (UN1385), not PG I.
11 Self-heating substances and mixtures Category 1


Danger
H251 P235
P280
P407
P410
P413
P420
It was classified in Category 1 because it is classified in Division 4.2, PG II in UNRTDG (UN1385).
12 Substances and mixtures which, in contact with water, emit flammable gases *
-
-
- - It is classified in Division 4.2, PG II in UNRTDG (UN1385), and it is not considered to be not applicable to Division 4.3. Therefore, it was classified as "Not classified."
13 Oxidizing liquids *
-
-
- - Solid (GHS definition). It was classified as "Not classified (Not applicable)."
14 Oxidizing solids *
-
-
- - Inorganic compounds containing no oxygen or halogen atoms. It was classified as "Not classified (Not applicable)."
15 Organic peroxides *
-
-
- - Inorganic substance. It was classified as "Not classified (Not applicable)."
16 Corrosive to metals *
-
-
- - Classification is not possible because test methods applicable to solid substances are not available.
17 Desensitized explosives *
-
-
- - There are no chemical groups associated with explosive properties present in the molecule. It was classified as "Not classified."

HEALTH HAZARDS
Hazard class Classification Pictogram
Signal word
Hazard statement
(code)
Precautionary statement
(code)
Rationale for the classification
1 Acute toxicity (Oral) Category 3


Danger
H301 P301+P310
P264
P270
P321
P330
P405
P501
[Rationale for the Classification]
Based on (1) and (2), it was classified in Category 3.

[Evidence Data]
(1) LD50 for rats: 208 mg/kg (HSDB (Access on June 2019))
(2) LD50 for mice: 205 mg/kg (HSDB (Access on June 2019))
1 Acute toxicity (Dermal) *
-
-
- - [Rationale for the Classification]
Classification not possible due to lack of data.
1 Acute toxicity (Inhalation: Gases) *
-
-
- - [Rationale for the Classification]
Solid (GHS definition). It was classified as "Not classified (Not applicable)."
1 Acute toxicity (Inhalation: Vapours) *
-
-
- - [Rationale for the Classification]
Classification not possible due to lack of data.
1 Acute toxicity (Inhalation: Dusts and mists) *
-
-
- - [Rationale for the Classification]
Classification not possible due to lack of data.
2 Skin corrosion/irritation Category 1


Danger
H314 P301+P330+P331
P303+P361+P353
P305+P351+P338
P304+P340
P260
P264
P280
P310
P321
P363
P405
P501
[Rationale for the Classification]
Based on (1), it was classified in Category 1.

[Evidence Data]
(1) This substance is a strong alkali, and it is a strong irritant to the mucous membrane and the skin (HSDB (Access on June 2019)).

[Reference Data, etc.]
(2) This substance was classified in "Skin Corr. 1B (H314)" in the EU CLP classification (EU CLP classification (Access on August 2019)).
3 Serious eye damage/eye irritation Category 1


Danger
H318 P305+P351+P338
P280
P310
[Rationale for the Classification]
Based on (1) and (2), it was classified in Category 1.

[Evidence Data]
(1) This substance is a strong alkali and causes burns on contact with the eyes (HSDB (Access on June 2019)).
(2) This substance was classified in Skin Corrosion (Category 1).
4 Respiratory sensitization *
-
-
- - [Rationale for the Classification]
Classification not possible due to lack of data.
4 Skin sensitization *
-
-
- - [Rationale for the Classification]
Classification not possible due to lack of data.
5 Germ cell mutagenicity *
-
-
- - [Rationale for the Classification]
Based on (1) and (2), since the results of all standard combination tests, including in vivo and in vitro tests, were negative, it was classified as "Not classified."

[Evidence Data]
(1) As for in vivo, a negative result was reported in a micronucleus test with mouse bone marrows (REACH registration dossier (Access on August 2019)).
(2) As for in vitro, negative results were reported in a bacterial reverse mutation test and a mouse lymphoma assay (REACH registration dossier (Access on August 2019)).
6 Carcinogenicity *
-
-
- - [Rationale for the Classification]
Classification not possible due to lack of data.
7 Reproductive toxicity *
-
-
- - [Rationale for the Classification]
Classification not possible due to lack of data.
8 Specific target organ toxicity - Single exposure Category 3 (Respiratory tract irritation)


Warning
H335 P304+P340
P403+P233
P261
P271
P312
P405
P501
[Rationale for the Classification]
Based on (1), it is considered that respiratory tract irritation occurs by inhalation exposure. Therefore, it was classified in Category 3 (respiratory tract irritation). Since ICSC (J) used in the previous classification is an information source in List 3, and details were unknown, it was not adopted. The classification result was changed from the previous classification by the use of the new information source.

[Evidence Data]
(1) There is a description that this substance is irritating to the skin and the mucous membranes (HSDB (Access on June 2019)).
9 Specific target organ toxicity - Repeated exposure *
-
-
- - [Rationale for the Classification]
Classification not possible due to lack of data.
10 Aspiration hazard *
-
-
- - [Rationale for the Classification]
Classification not possible due to lack of data.

ENVIRONMENTAL HAZARDS
Hazard class Classification Pictogram
Signal word
Hazard statement
(code)
Precautionary statement
(code)
Rationale for the classification
11 Hazardous to the aquatic environment Short term (Acute) Category 1


Warning
H400 P273
P391
P501
It was classified in Category 1 from 48-hour LC50 = 0.55 mg/L for crustacea (Daphnia pulex) (AQUIRE, 2019, Lee, 1976).
11 Hazardous to the aquatic environment Long term (Chronic) Not classified
-
-
- - Reliable chronic toxicity data were not obtained. Although the dynamics of the inorganic compound are unclear in the environment, it was thought that after dissociation in water, the aqueous solution becoming strongly alkaline is the main reason for its toxicity. Because a toxicity effect will be diminished by a buffering action in the aquatic environment, it was classified as "Not classified."
12 Hazardous to the ozone layer Classification not possible
-
-
- - Classification not possible due to lack of data.


NOTE:
  • GHS Classification Result by the Japanese Government is intended to provide a reference for preparing a GHS label or SDS for users. To include the same classification result in a label or SDS for Japan is NOT mandatory.
  • Users can cite or copy this classification result when preparing a GHS label or SDS. Please be aware, however, that the responsibility for a label or SDS prepared by citing or copying this classification result lies with users.
  • This GHS classification was conducted based on the information sources and the guidance for classification and judgement which are described in the GHS Classification Guidance for the Japanese Government etc. Using other literature, test results etc. as evidence and including different content from this classification result in a label or SDS are allowed.
  • Hazard statement and precautionary statement will show by hovering the mouse cursor over a code in the column of "Hazard statement" and "Precautionary statement," respectively. In the excel file, both the codes and statements are provided.
  • A blank or "-" in the column of "Classification" denotes that a classification for the hazard class was not conducted in the year.
  • An asterisk “*” in the column of “Classification” denotes that “Not classified (or No applicable)” and/or “Classification not possible” is applicable. Details are described in the column of “Rationale for the classification”. If no English translation is available for “Rationale for the classification,” please refer to the Japanese version of the results.

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