Item | Information |
---|---|
CAS RN | 129-15-7 |
Chemical Name | 2-methyl-1-nitroanthraquinone |
Substance ID | R01-B-106 |
Classification year (FY) | FY2019 |
Ministry who conducted the classification | Ministry of Health, Labour and Welfare (MHLW)/Ministry of the Environment (MOE) |
New/Revised | Revised |
Classification result in other fiscal year | FY2006 |
Download of Excel format | Excel file |
Item | Information |
---|---|
Guidance used for the classification (External link) | GHS Classification Guidance for the Japanese Government (FY2013 revised edition (Ver. 1.1)) |
UN GHS document (External link) | UN GHS document |
Definitions/Abbreviations (Excel file) | Definitions/Abbreviations |
Model Label by MHLW (External link) | |
Model SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
OECD/eChemPortal (External link) | eChemPortal |
Hazard class | Classification |
Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
1 | Explosives | * |
- |
- | - | There is a chemical group associated with explosive properties (nitro group) present in the molecule, and the calculated oxygen balance is -183, higher than the criteria: -200, but the classification is not possible due to no data. |
2 | Flammable gases | * |
- |
- | - | Solid (GHS definition). It was classified as "Not classified (Not applicable)." |
3 | Aerosols | * |
- |
- | - | Not aerosol products. It was classified as "Not classified (Not applicable)." |
4 | Oxidizing gases | * |
- |
- | - | Solid (GHS definition). It was classified as "Not classified (Not applicable)." |
5 | Gases under pressure | * |
- |
- | - | Solid (GHS definition). It was classified as "Not classified (Not applicable)." |
6 | Flammable liquids | * |
- |
- | - | Solid (GHS definition). It was classified as "Not classified (Not applicable)." |
7 | Flammable solids | * |
- |
- | - | No data available. |
8 | Self-reactive substances and mixtures | * |
- |
- | - | There is a chemical group associated with explosive properties (nitro group) present in the molecule, but the classification is not possible due to no data. |
9 | Pyrophoric liquids | * |
- |
- | - | Solid (GHS definition). It was classified as "Not classified (Not applicable)." |
10 | Pyrophoric solids | * |
- |
- | - | No data available. |
11 | Self-heating substances and mixtures | * |
- |
- | - | No data available. |
12 | Substances and mixtures which, in contact with water, emit flammable gases | * |
- |
- | - | The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At). It was classified as "Not classified (Not applicable)." |
13 | Oxidizing liquids | * |
- |
- | - | Solid (GHS definition). It was classified as "Not classified (Not applicable)." |
14 | Oxidizing solids | * |
- |
- | - | The substance is an organic compound containing oxygen (but not fluorine or chlorine), which is chemically bonded to an element (N) other than carbon or hydrogen. However, the classification is not possible due to no data. |
15 | Organic peroxides | * |
- |
- | - | Organic compounds containing no bivalent -O-O- structure in the molecule. It was classified as "Not classified (Not applicable)." |
16 | Corrosive to metals | * |
- |
- | - | Classification is not possible because test methods applicable to solid substances are not available. |
17 | Desensitized explosives | * |
- |
- | - | It was classified as "Not classified" because it is not desensitized by wetting, dilution, etc. |
Hazard class | Classification |
Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | * |
- |
- | - |
[Rationale for the Classification] Classification not possible due to lack of data. |
1 | Acute toxicity (Dermal) | * |
- |
- | - |
[Rationale for the Classification] Classification not possible due to lack of data. |
1 | Acute toxicity (Inhalation: Gases) | * |
- |
- | - |
[Rationale for the Classification] Solid (GHS definition). It was classified as "Not classified (Not applicable)." |
1 | Acute toxicity (Inhalation: Vapours) | * |
- |
- | - |
[Rationale for the Classification] Classification not possible due to lack of data. |
1 | Acute toxicity (Inhalation: Dusts and mists) | * |
- |
- | - |
[Rationale for the Classification] Classification not possible due to lack of data. |
2 | Skin corrosion/irritation | * |
- |
- | - |
[Rationale for the Classification] Classification not possible due to lack of data. |
3 | Serious eye damage/eye irritation | * |
- |
- | - |
[Rationale for the Classification] Classification not possible due to lack of data. |
4 | Respiratory sensitization | * |
- |
- | - |
[Rationale for the Classification] Classification not possible due to lack of data. |
4 | Skin sensitization | * |
- |
- | - |
[Rationale for the Classification] Classification not possible due to lack of data. |
5 | Germ cell mutagenicity | * |
- |
- | - |
[Rationale for the Classification] There are no in vivo data. Therefore, classification was not possible due to lack of data. [Evidence Data] (1) As for in vitro, there are reports that it was positive in bacterial reverse mutation tests and a chromosomal aberration test (IARC 27 (1982), NTP DB (Access on October 2019)). |
6 | Carcinogenicity | Category 2 |
Warning |
H351 |
P308+P313
P201 P202 P280 P405 P501 |
[Rationale for the Classification] Based on classification results by other organizations of (1), it was classified in Category 2 in accordance with the GHS Classification Guidance for the Japanese Government. [Evidence Data] (1) As for classification results by domestic and international organizations, it was classified in Group 2B by IARC (IARC Sup.7 (1987)), and Group 2B by the Japan Society For Occupational Health (JSOH) (Recommendation of Occupational Exposure Limits, 1991). |
7 | Reproductive toxicity | * |
- |
- | - |
[Rationale for the Classification] Classification not possible due to lack of data. |
8 | Specific target organ toxicity - Single exposure | * |
- |
- | - |
[Rationale for the Classification] Classification not possible due to lack of data. |
9 | Specific target organ toxicity - Repeated exposure | Category 2 (stomach) |
Warning |
H373 |
P260
P314 P501 |
[Rationale for the Classification] Based on (1), it was classified in Category 2 (stomach). Besides, though gastric lesions may be local effects due to irritation, the stomach was adopted as the target organ since no information on the irritancy of this substance was available. [Evidence Data] (1) In a 78-week carcinogenicity test with rats dosed by feeding at 0.06 and 0.12% (30 and 60 mg/kg/day, within the range of Category 2), nonneoplastic stomach lesions (basal cell hyperplasia, hyperkeratosis, acanthosis) were observed (NTP TR29 (1978)). [Reference Data, etc.] (2) In a 6-week test with rats dosed by feeding at 0.05-5.0%, reductions in weight gain (14% for male, 3% for female) were observed at or above 0.15% (converted guidance value: 35 mg/kg/day, within the range of Category 2) (IARC 27 (1982)). |
10 | Aspiration hazard | * |
- |
- | - |
[Rationale for the Classification] Classification not possible due to lack of data. |
Hazard class | Classification |
Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment Short term (Acute) | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
11 | Hazardous to the aquatic environment Long term (Chronic) | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
12 | Hazardous to the ozone layer | Classification not possible |
- |
- | - | Classification not possible due to lack of data. |
|