NITE - Chemical Management Field

GHS Classification Results by the Japanese Government

GENERAL INFORMATION

Item	Information
CAS RN	1314-80-3
Chemical Name	Diphosphorus pentasulfide
Substance ID	R01-B-111
Classification year (FY)	FY2019
Ministry who conducted the classification	Ministry of Health, Labour and Welfare (MHLW)/Ministry of the Environment (MOE)
New/Revised	Revised
Classification result in other fiscal year	FY2006
Download of Excel format	Excel file

REFERENCE INFORMATION

Item	Information
Guidance used for the classification (External link)	GHS Classification Guidance for the Japanese Government (FY2013 revised edition (Ver. 1.1))
UN GHS document (External link)	UN GHS document
Definitions/Abbreviations (Excel file)	Definitions/Abbreviations
Model Label by MHLW (External link)
Model SDS by MHLW (External link)	MHLW Website (in Japanese Only)
OECD/eChemPortal (External link)	eChemPortal

PHYSICAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification
1	Explosives	*	- -	-	-	There are no chemical groups associated with explosive properties present in the molecule. It was classified as "Not classified (Not applicable)."
2	Flammable gases	*	- -	-	-	Solid (GHS definition). It was classified as "Not classified (Not applicable)."
3	Aerosols	*	- -	-	-	Not aerosol products. It was classified as "Not classified (Not applicable)."
4	Oxidizing gases	*	- -	-	-	Solid (GHS definition). It was classified as "Not classified (Not applicable)."
5	Gases under pressure	*	- -	-	-	Solid (GHS definition). It was classified as "Not classified (Not applicable)."
6	Flammable liquids	*	- -	-	-	Solid (GHS definition). It was classified as "Not classified (Not applicable)."
7	Flammable solids	Category 1 or 2	- -	-	-	Because it is classified in Division 4.3, Subsidiary Risk 4.1 in UNRTDG (UN1340), it corresponds to flammable solids. However, it was classified in Category 1 or Category 2 because PG is unknown for Subsidiary Risk.
8	Self-reactive substances and mixtures	*	- -	-	-	There are no chemical groups present in the molecule associated with explosive or self-reactive properties. It was classified as "Not classified (Not applicable)."
9	Pyrophoric liquids	*	- -	-	-	Solid (GHS definition). It was classified as "Not classified (Not applicable)."
10	Pyrophoric solids	*	- -	-	-	It was classified as "Not classified" because it is estimated that it does not ignite at normal temperatures from an autoignition temperature of 142 deg C (NFPA (14th, 2010)).
11	Self-heating substances and mixtures	*	- -	-	-	No data available.
12	Substances and mixtures which, in contact with water, emit flammable gases	Category 2	Danger	H261	P302+P335+P334 P231+P232 P370+P378 P402+P404 P223 P280 P501	It contains a metal (P), and because it is classified in Division 4.3, Subsidiary Risk 4.1, PG II in UNRTDG (UN1340), it was classified in Category 2.
13	Oxidizing liquids	*	- -	-	-	Solid (GHS definition). It was classified as "Not classified (Not applicable)."
14	Oxidizing solids	*	- -	-	-	Inorganic compound containing no oxygen or halogen. It was classified as "Not classified (Not applicable)."
15	Organic peroxides	*	- -	-	-	Inorganic compound. It was classified as "Not classified (Not applicable)."
16	Corrosive to metals	*	- -	-	-	Classification is not possible because test methods applicable to solid substances are not available.
17	Desensitized explosives	*	- -	-	-	There are no chemical groups associated with explosive properties present in the molecule. It was classified as "Not classified."

HEALTH HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification
1	Acute toxicity (Oral)	Category 4	Warning	H302	P301+P312 P264 P270 P330 P501	[Rationale for the Classification] Based on (1), it was classified in Category 4. [Evidence Data] (1) LD50 for rats: 389 mg/kg (HSDB (Access on October 2019))
1	Acute toxicity (Dermal)	*	- -	-	-	[Rationale for the Classification] Based on (1), it was classified as "Not classified." [Evidence Data] (1) LD50 for rabbits: 3,160 mg/kg (HSDB (Access on October 2019))
1	Acute toxicity (Inhalation: Gases)	*	- -	-	-	[Rationale for the Classification] Solid (GHS definition). It was classified as "Not classified (Not applicable)."
1	Acute toxicity (Inhalation: Vapours)	*	- -	-	-	[Rationale for the Classification] Classification not possible due to lack of data.
1	Acute toxicity (Inhalation: Dusts and mists)	*	- -	-	-	[Rationale for the Classification] Classification not possible due to lack of data.
2	Skin corrosion/irritation	Category 2	Warning	H315	P302+P352 P332+P313 P362+P364 P264 P280 P321	[Rationale for the Classification] Based on (1)-(3), it was classified in Category 2. [Evidence Data] (1) Major toxic effects of this substance were irritation due to mainly phosphoric acid (CAS RN 7664-38-2) and hydrogen sulfide (CAS RN 7783-06-4), hydrolysates of this substance (PATTY (6th, 2012), ACGIH (7th, 2001), GESTIS (Access on October 2019)). (2) Major toxic effects of this substance were irritation to the eyes, skin and respiratory tract (GESTIS (Access on October 2019)). (3) Prolonged skin contacts with this substance caused irritation and might cause dermatitis (HSDB (Access on October 2019), GESTIS (Access on October 2019)).
3	Serious eye damage/eye irritation	Category 2	Warning	H319	P305+P351+P338 P337+P313 P264 P280	[Rationale for the Classification] Based on (1) and (2), it was classified in Category 2. The category was changed due to the new data obtained. [Evidence Data] (1) Major toxic effects of this substance were irritation due to mainly phosphoric acid (CAS RN 7664-38-2) and hydrogen sulfide (CAS RN 7783-06-4), hydrolysates of this substance (PATTY (6th, 2012), ACGIH (7th, 2001), GESTIS (Access on October 2019)). (2) At concentrations of 20 ppm, due to the effects of hydrogen sulfide, which was formed by hydrolysis, this substance begins acting as an irritant on the mucous membranes of the eyes and respiratory tract, and the effects increase with concentration and exposure time. Eye irritation is characterized by irritation of the conjunctiva with photophobia (increased light sensitivity) to keratoconjunctivitis and vesiculation of the cornea epithelium (HSDB (Access on October 2019)).
4	Respiratory sensitization	*	- -	-	-	[Rationale for the Classification] Classification not possible due to lack of data.
4	Skin sensitization	*	- -	-	-	[Rationale for the Classification] Classification not possible due to lack of data.
5	Germ cell mutagenicity	*	- -	-	-	[Rationale for the Classification] Classification not possible due to lack of data.
6	Carcinogenicity	*	- -	-	-	[Rationale for the Classification] Classification not possible due to lack of data.
7	Reproductive toxicity	*	- -	-	-	[Rationale for the Classification] Classification not possible due to lack of data.
8	Specific target organ toxicity - Single exposure	Category 3 (Respiratory tract irritation)	Warning	H335	P304+P340 P403+P233 P261 P271 P312 P405 P501	[Rationale for the Classification] Based on (1)-(3), it was classified in Category 3 (respiratory tract irritation). By using the new information sources, the classification result was changed from the previous classification. [Evidence Data] (1) Major effects of this substance by inhalation exposure were irritation of the respiratory tract, and inhalation at 10 mg/m3 (in the air concentration) caused pulmonary irritation (ACGIH (7th, 2001)). (2) Major toxic effects of this substance were irritation due to mainly phosphoric acid (CAS RN 7664-38-2) and hydrogen sulfide (CAS RN 7783-06-4), hydrolysates of this substance (ACGIH (7th, 2001), GESTIS (Access on October 2019)). (3) Major toxic effects of this substance were irritation to the eyes, skin and respiratory tract (GESTIS (Access on October 2019)).
9	Specific target organ toxicity - Repeated exposure	*	- -	-	-	[Rationale for the Classification] Classification not possible due to lack of data. [Reference Data, etc.] (1) Prolonged skin contacts with this substance caused irritation and might cause dermatitis (HSDB (Access on October 2019), GESTIS (Access on October 2019)).
10	Aspiration hazard	*	- -	-	-	[Rationale for the Classification] Classification not possible due to lack of data.

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification
11	Hazardous to the aquatic environment Short term (Acute)	Classification not possible	- -	-	-	Classification not possible due to lack of data.
11	Hazardous to the aquatic environment Long term (Chronic)	Classification not possible	- -	-	-	Classification not possible due to lack of data.
12	Hazardous to the ozone layer	Classification not possible	- -	-	-	Classification not possible due to lack of data.

NOTE:

GHS Classification Result by the Japanese Government is intended to provide a reference for preparing a GHS label or SDS for users. To include the same classification result in a label or SDS for Japan is NOT mandatory.
Users can cite or copy this classification result when preparing a GHS label or SDS. Please be aware, however, that the responsibility for a label or SDS prepared by citing or copying this classification result lies with users.
This GHS classification was conducted based on the information sources and the guidance for classification and judgement which are described in the GHS Classification Guidance for the Japanese Government etc. Using other literature, test results etc. as evidence and including different content from this classification result in a label or SDS are allowed.
Hazard statement and precautionary statement will show by hovering the mouse cursor over a code in the column of "Hazard statement" and "Precautionary statement," respectively. In the excel file, both the codes and statements are provided.
A blank or "-" in the column of "Classification" denotes that a classification for the hazard class was not conducted in the year.
An asterisk “*” in the column of “Classification” denotes that “Not classified (or No applicable)” and/or “Classification not possible” is applicable. Details are described in the column of “Rationale for the classification”. If no English translation is available for “Rationale for the classification,” please refer to the Japanese version of the results.

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