NITE - Chemical Management Field

GHS Classification Results by the Japanese Government

GENERAL INFORMATION

Item	Information
CAS RN	79622-59-6
Chemical Name	3-chloro-N-(3-chloro-5-trifluoromethyl-2-pyridyl)-alpha,alpha,alpha-trifluoro-2,6-dinitro-p-toluidine; Fluazinam
Substance ID	R02-B-121-MHLW
Classification year (FY)	FY2020
Ministry who conducted the classification	Ministry of Health, Labour and Welfare (MHLW)
New/Revised	Revised
Classification result in other fiscal year	FY2006
Download of Excel format	Excel file

REFERENCE INFORMATION

Item	Information
Guidance used for the classification (External link)	GHS Classification Guidance for the Japanese Government (FY2019 revised edition (Ver. 2.0))
UN GHS document (External link)	UN GHS document
Definitions/Abbreviations (Excel file)	Definitions/Abbreviations
Model Label by MHLW (External link)	MHLW Website (in Japanese Only)
Model SDS by MHLW (External link)	MHLW Website (in Japanese Only)
OECD/eChemPortal (External link)	eChemPortal

PHYSICAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification
1	Explosives	Classification not possible	- -	-	-	There is a chemical group associated with explosive properties, a nitro group, present in the molecule, and the calculated oxygen balance is -83, higher than the criteria: -200, but the classification is not possible due to no data. Besides, there is information that no explosion occurred on the test conditions (RAC Background Document (2012)).
2	Flammable gases	Not classified (Not applicable)	- -	-	-	Solid (GHS definition). It was classified as "Not classified."
3	Aerosols	Not classified (Not applicable)	- -	-	-	Not aerosol products. It was classified as "Not classified."
4	Oxidizing gases	Not classified (Not applicable)	- -	-	-	Solid (GHS definition). It was classified as "Not classified."
5	Gases under pressure	Not classified (Not applicable)	- -	-	-	Solid (GHS definition). It was classified as "Not classified."
6	Flammable liquids	Not classified (Not applicable)	- -	-	-	Solid (GHS definition). It was classified as "Not classified."
7	Flammable solids	Classification not possible	- -	-	-	No data available.
8	Self-reactive substances and mixtures	Classification not possible	- -	-	-	There is a chemical group associated with explosive properties, a nitro group, present in the molecule, but the classification is not possible due to no data.
9	Pyrophoric liquids	Not classified (Not applicable)	- -	-	-	Solid (GHS definition). It was classified as "Not classified."
10	Pyrophoric solids	Classification not possible	- -	-	-	It was classified as "Not classified" because it is estimated that it does not ignite at normal temperatures from an autoignition temperature of > 400 deg C (RAC Background Document (2012)).
11	Self-heating substances and mixtures	Classification not possible	- -	-	-	Classification is not possible because test methods applicable to solid (melting point <= 140 deg C) substances are not available.
12	Substances and mixtures which, in contact with water, emit flammable gases	Not classified (Not applicable)	- -	-	-	The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At). It was classified as "Not classified."
13	Oxidizing liquids	Not classified (Not applicable)	- -	-	-	Solid (GHS definition). It was classified as "Not classified."
14	Oxidizing solids	Classification not possible	- -	-	-	The substance is an organic compound containing fluorine, chlorine, and oxygen, and the oxygen is chemically bonded to the element other than carbon or hydrogen (N). However, the classification is not possible due to no data. Besides, there is information that the substance is not oxidizing (RAC Background Document (2012)).
15	Organic peroxides	Not classified (Not applicable)	- -	-	-	Organic compounds containing no bivalent -O-O- structure in the molecule. It was classified as "Not classified."
16	Corrosive to metals	Classification not possible	- -	-	-	Classification is not possible because test methods applicable to solid substances are not available.
17	Desensitized explosives	Classification not possible	- -	-	-	There is a chemical group associated with explosive properties, a nitro group, present in the molecule, but the classification is not possible due to no data.

HEALTH HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification
1	Acute toxicity (Oral)	Not classified	- -	-	-	[Rationale for the Classification] It was classified as "Not classified" from (1) - (3). [Evidence Data] (1) LD50 for rats: females: 4,100 mg/kg, males: 4,500 mg/kg (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019), A pesticide abstract and evaluation report (Food and Agricultural Materials Inspection Center, 2012)) (2) LD50 for rats: >= 4,100 mg/kg (EU CLP CLH (2012), EU EFSA (2008)) (3) LD50 for rats: > 5,000 mg/kg (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019), A pesticide abstract and evaluation report (Food and Agricultural Materials Inspection Center, 2012))
1	Acute toxicity (Dermal)	Not classified	- -	-	-	[Rationale for the Classification] It was classified as "Not classified" from (1). [Evidence Data] (1) LD50 for rats: > 2,000 mg/kg (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019), EU CLP CLH (2012), EU EFSA (2008), A pesticide abstract and evaluation report (Food and Agricultural Materials Inspection Center, 2012))
1	Acute toxicity (Inhalation: Gases)	Not classified	- -	-	-	[Rationale for the Classification] Solid (GHS definition). It was classified as "Not classified."
1	Acute toxicity (Inhalation: Vapours)	Classification not possible	- -	-	-	[Rationale for the Classification] Classification not possible due to lack of data.
1	Acute toxicity (Inhalation: Dusts and mists)	Category 4	Warning	H332	P304+P340 P261 P271 P312	[Rationale for the Classification] From (1), because the death of 2 out of 10 animals (2/5 males) was observed at 1.1 mg/L, it was classified in Category 4. Besides, the value in (2) was within the guidance value range for Category 2, but effects by oral and dermal administration were considered due to whole-body exposure, and using PEG 400 as a solvent, which completely dissolved this substance, was regarded as inappropriate for exposure to dust aerosol. And the classification was conducted based on data in (1), which was performed according to new TG, and (2) was taken as reference data. The classification result was changed from the previous classification by using new information sources. [Evidence Data] (1) LC50 for rats (nose exposure, 4 hours): > 1.1 mg/L (2 out of 10 animals died at 1.1 mg/L (2/5 males)) (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019), EU CLP CLH (2012), EU EFSA (2008), A pesticide abstract and evaluation report (Food and Agricultural Materials Inspection Center, 2012)) [Reference Data, etc.] (2) LC50 for rats (whole-body exposure, 4 hours): males: 0.463 mg/L, females: 0.476 mg/L (PEG400 used as a solvent) (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019), CLH Report (2011), A pesticide abstract and evaluation report (Food and Agricultural Materials Inspection Center, 2012))
2	Skin corrosion/irritation	Not classified	- -	-	-	[Rationale for the Classification] It was classified as "Not classified" from (1) - (3). [Evidence Data] (1) In a skin irritation test by 4-hour occlusive application to rabbits according to EPA OPP 81-5, very slight to well-defined erythema was observed but disappeared by day 14. The mean score at 24/48/72 hours after application was 0.8 (RAC Background Document (2012), A pesticide abstract and evaluation report (Food and Agricultural Materials Inspection Center, 2012)). (2) In a skin irritation test with rabbits, minimal to slight irritation was shown (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019), EU EFSA (2008)). (3) In a skin irritation test with rabbits, no skin reactions were seen in normal skin (A pesticide abstract and evaluation report (Food and Agricultural Materials Inspection Center, 2012)).
3	Serious eye damage/eye irritation	Category 1	Danger	H318	P305+P351+P338 P280 P310	[Rationale for the Classification] It was classified in Category 1 from (1), (2). The classification result was changed because symptoms such as corneal opacity persisted by day 21. [Evidence Data] (1) In an eye irritation test with rabbits (n = 6) on this substance, corneal opacity of the score of 1 or more and less than 3 was found in all the animals and persisted by 21 days after application. Iridial effects were observed in 4/6 animals and persisted in one animal by 21 days after application. Conjunctival effects were seen in all the animals and persisted in one animal by 21 days after application (EU CLP CLH (2012), RAC Background Document (2012), A pesticide abstract and evaluation report (Food and Agricultural Materials Inspection Center, 2012)). (2) In an eye irritation test with rabbits, it was severely irritating (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019), EU EFSA (2008)). [Reference Data, etc.] (3) It was classified in Eye Dam. 1 (H318) in EU-CLP classification (EU CLP classification (Access on December 2020)).
4	Respiratory sensitization	Classification not possible	- -	-	-	[Rationale for the Classification] Classification not possible due to lack of data.
4	Skin sensitization	Category 1B	Warning	H317	P302+P352 P333+P313 P362+P364 P261 P272 P280 P321 P501	[Rationale for the Classification] It was classified in Category 1B from (1), (2). Because it was possible to confirm sufficient data for sub-categorization (2), sub-categorization was conducted. [Evidence Data] (1) In skin sensitization tests with guinea pigs (a maximization test and Buehler tests), positive responses were shown, and it was judged as sensitizing, although its degree depended on the purity (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019), EU EFSA (2008), A pesticide abstract and evaluation report (Food and Agricultural Materials Inspection Center, 2012)). (2) In a skin sensitization test with guinea pigs (Buehler test, application concentration 50%), there were positive reactions (positive rate 85%), and it was judged as sensitizing (A pesticide abstract and evaluation report (Food and Agricultural Materials Inspection Center, 2012)). [Reference Data, etc.] (3) In a skin sensitization test with guinea pigs on this substance (maximization test, intradermal administration 10%), skin responses were observed in 5/10 animals (positive rate 50%) 24 hours after the challenge and 2/10 animals (positive rate 20%) after 48 hours, and it was reported to be positive (EU CLP CLH (2012), A pesticide abstract and evaluation report (Food and Agricultural Materials Inspection Center, 2012)). (4) In a skin sensitization test with guinea pigs on this substance (maximization test), no skin responses were seen (EU CLP CLH (2012)). (5) In a skin sensitization test with guinea pigs on this substance (Buehler test, application concentration 50%), skin responses were found in 9/20 animals challenged with this substance and 1/10 in the control group, and it was positive (positive rate 35%), but as a result of re-challenge, the final positive rate was reported as 5% (EU CLP CLH (2012), A pesticide abstract and evaluation report (Food and Agricultural Materials Inspection Center, 2012)). (6) In a skin sensitization test with guinea pigs (Buehler test, application concentration 100%), it was negative (A pesticide abstract and evaluation report (Food and Agricultural Materials Inspection Center, 2012)). (7) It was classified in Skin Sens. 1A (H317) in EU-CLP classification (EU CLP classification (Access on December 2020)).
5	Germ cell mutagenicity	Not classified	- -	-	-	[Rationale for the Classification] It was classified as "Not classified" from (1), (2). [Evidence Data] (1) As for in vivo, it was reported to be negative in micronucleus tests with bone marrow cells after oral administration to mice or Chinese hamsters (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). (2) As for in vitro, it was reported to be negative in a bacterial reverse mutation test, a chromosomal aberration test, a gene mutation test, and an unscheduled DNA synthesis test using cultured mammalian cells (same as the above).
6	Carcinogenicity	Category 2	Warning	H351	P308+P313 P201 P202 P280 P405 P501	[Rationale for the Classification] It was classified in Category 2 from (1) - (3). The classification result was changed by using new information sources. [Evidence Data] (1) As for classification results by domestic and international organizations, EPA classified it in S (Suggestive Evidence Of Carcinogenicity, But Not Sufficient To Assess Human Carcinogenic Potential) (EPA Annual Cancer Report 2019 (Access on November 2020): classified in 2001). (2) In a combined chronic toxicity/carcinogenicity test by 2-year diet administration of this substance to male and female rats, a trend toward an increase in follicular epithelial cell adenoma and adenocarcinoma and a significant increase in the combined incidence of follicular epithelial cell tumors were observed in the thyroid of males. In females, no treatment-related increases in neoplastic lesions were found (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). (3) In two carcinogenicity tests by 2-year diet administration of this substance to male and female mice, in both the tests, significant increases in the incidences of hepatocellular adenoma and hepatocellular adenoma and adenocarcinoma (combined) were observed in males. No treatment-related increases in neoplastic lesions were seen in females (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)).
7	Reproductive toxicity	Category 1B	Danger	H360	P308+P313 P201 P202 P280 P405 P501	[Rationale for the Classification] Based on (1) to (3), severe toxicity was observed in fetuses at a dose at which maternal toxicity was observed, and therefore, it was classified in Category 1B. Based on new information sources, the classification result were changed from the previous classification. [Evidence Data] (1) In a developmental toxicity study with female rats dosed by gavage (vehicle: corn oil) on days 6 to 15 of gestation, an increase in the incidence of external abnormalities such as small fetuses, cleft upper jaw, and deformed palate was observed in fetuses at a dose (250 mg/kg/day) at which maternal toxicity (soiling of the urogenital organ, reduced body weight gain, a decrease in food consumption) was observed (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). (2) In a developmental toxicity study with female rats dosed by gavage (vehicle: aqueous solution in 0.5% CMC-Na) on days 6 to 19 of gestation, effects were observed in fetuses at doses (50 mg/kg/day or above) at which maternal toxicity (reduced body weight gain, a decrease in food consumption, an increase in absolute liver weight) was observed, and low body weights and skeletal variations (the number of vertebral bodies before the sacral vertebra: 27, incomplete ossification of the skull bones and vertebral arch, and unossified sternebrae) of fetuses at 50 mg/kg/day, and a decrease in the number of live fetuses and an increase in post-implantation embryo death at 300 mg/kg/day were observed. No teratogenicity was observed (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). (3) In a developmental toxicity study with female rabbits dosed by gavage (vehicle: aqueous solution in 1% CMC-Na) on days 6 to 19 of gestation, fetal toxicity (an increase in post-implantation embryonic mortality at or above 4 mg/kg/day, an increase in incomplete ossification of the metacarpal bones and phalanges without significant difference at or above 7 mg/kg/day, death of all fetuses, and abnormalities of the parietal bone and sternebral fusions without significant difference at 12 mg/kg/day) was observed at doses at which maternal toxicity (abortion, hepatocyte hypertrophy, and pulmonary edema or retention of pleural effusion at or above 4 mg/kg/day, a decrease in food consumption at or above 7 mg/kg/day, reduced body weight gain at 12 mg/kg/day) was observed (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). [Reference Data, etc.] (4) In a two-generation reproductive study with rats dosed by feeding, reduced body weight gain, increases in absolute and relative liver weight, etc. were observed as parental toxicity, and reduced body weight gain was observed in offspring, but no effect on fertility was observed (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). (5) In a developmental neurotoxicity test with female rats dosed by gavage from day 6 of gestation until day 20 of lactation, no developmental neurotoxicity was observed (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). (6) In the EU CLP Classification, it was classified in Repr. 2 (Classification in EU CLP (Access on December 2020)).
8	Specific target organ toxicity - Single exposure	Category 1 (respiratory organs), Category 3 (narcotic effects)	Danger Warning	H370 H336	P308+P311 P260 P264 P270 P321 P405 P501 P304+P340 P403+P233 P261 P271 P312	[Rationale for the Classification] There was no report on effects of an acute exposure to this substance in humans. In test animals, based on (1) and (2), it was classified in Category 1 (respiratory organs), and based on (3), it was classified in Category 3 (narcotic effects). New information sources were used and the classification results were changed from the previous classification. [Evidence Data] (1) In a 4-hour inhalation exposure test (systemic exposure) with rats, a decrease in locomotor activity, stained fur and snout, a decrease in respiration, ocular cloudiness, low body weight, etc. were observed in males at 0.304 mg/L and in females at 0.561 mg/L (within the range for Category 1 in both sexes). In a gross pathological examination of dead animals, nasal discharge, hyperemia and hemorrhage of the lung, retention of gas in the stomach, etc. were observed, and the cause of death was presumed to be primarily respiratory failure (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). (2) In a 4-hour inhalation exposure test (nasal exposure) with rats, stained fur and snout, dyspnea, rales, yellow to red eye discharges, eyelid closure, clear nasal discharge, and decreased excretion of feces and urine were observed at 1.1 mg/L (within the range for Category 2) (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). (3) In an acute oral toxicity test with rats, piloerection, hunchback position, abnormal gait, lethargy, paleness of the limbs, and diarrhea at or above 2,500 mg/kg (exceeding Category 2); ataxia in males at 3,200 mg/kg (exceeding Category 2); a decrease in respiration, and blepharoptosis at or above 3,200 mg/kg (exceeding Category 2); tremor in males, and prone position and ataxia in females at 4,000 mg/kg (exceeding Category 2); and prone position in males at 5,000 mg/kg (exceeding Category 2) were observed (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). [Reference Data, etc.] (4) In an acute oral toxicity test with rats, piloerection and diarrhea were observed at 5,000 mg/kg (exceeding Category 2) (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). (5) In an acute oral toxicity test with rats, a decrease in motility, hunchback position, piloerection, etc. were observed at 5,000 mg/kg (exceeding Category 2) (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). (6) In an acute oral toxicity test with dogs, vomiting, pale renal cortex, edema on the kidney surface, and pale liver were observed at 5,000 mg/kg (exceeding Category 2) (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)).
9	Specific target organ toxicity - Repeated exposure	Category 1 (liver, blood system)	Danger	H372	P260 P264 P270 P314 P501	[Rationale for the Classification] Based on (1) to (7), it was classified in Category 1 (liver, blood system). As a result of a review based on the new information, the classification results were changed from the previous classification. [Evidence Data] (1) As a result of a 90-day test with rats dosed by feeding, chronic inflammation of the cecum in males and females, slight anemia, centrilobular hepatocyte hypertrophy, and chronic inflammation of the hepatic sinusoid in males, and increased weight of the lungs and uterus in females were observed at 500 ppm (males/females: 38/44 mg/kg/day, within the range for Category 2) (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). (2) As a result of a 90-day oral toxicity test with dogs, gray spots in the choroidal tapetum of the eye, an increase in liver weight, and hepatic bile duct proliferation in males and females, and an increase in ALP in females were observed at 100 mg/kg/day (within the range for Category 2) (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). (3) As a result of a two-year chronic toxicity study with rats dosed by feeding, slight anemia (decreases in hematocrit, hemoglobin, MCHC, and erythrocyte count) was observed in females at 100 ppm (males/females: 3.9/4.9 mg/kg/day, within the range for Category 1) (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). (4) As a result of a two-year combined chronic toxicity/carcinogenicity study with rats dosed by feeding, slight anemia (decreases in hematocrit, hemoglobin, erythrocyte count, MCHC, and MCV) in males and females, and pericholangitis, centrilobular sinusoidal distension, and atrophy of the pancreatic exocrine gland in females were observed at 100 ppm (males/females: 3.82/4.87 mg/kg/day, within the range for Category 1), and an increase in total cholesterol, acidophilic hepatocellular foci, clear and vacuolated (fatty) centrilobular hepatocytes, bile duct hyperplasia, pericholangitis, pneumonitis, and cubic epithelium metaplasia of the alveolar epithelium in males and females, centrilobular sinusoidal distension, atrophy of the pancreatic exocrine gland, testicular atrophy, and sperm granuloma in males, and loss of fur (at the end of the study), centrilobular hepatocyte necrosis, lymph node sinus histiocytosis, and vacuolated (fatty) pancreatic acinar cells in females were observed at 1,000 ppm (males/females: 40/53 mg/kg/day, within the range for Category 2) (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). (5) As a result of a two-year combined chronic toxicity/carcinogenicity study with mice dosed by feeding, as non-neoplastic lesions, hepatic brown pigmentated macrophages were observed in males and females at or above 100 ppm (males/females: 10.7/11.7 mg/kg/day, within the range for Category 2), and hepatic granuloma formation and white matter vacuolation of the central nervous system in males and females, and an increase in basophilic and acidophilic hepatocellular foci in males were observed at 1,000 ppm (males/females: 107/117 mg/kg/day, exceeding Category 2). As for the white matter vacuolation of the central nervous system observed in the study, as a result of a test to confirm central nervous system toxicity, the effect that induced the white matter vacuolation of the central nervous system was not confirmed in this substance itself, and it was suggested that inclusion in the active ingredient (not identified) was the primary cause of the vacuolation (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). (6) As a result of a one-year chronic toxicity study with dogs, increases in leukocyte count and neutrophil count in males and females, and dry nose and increased percentage of the myelocyte/erythroblast in females were observed at or above 10 mg/kg/day (within the range for Category 1); and salivation, dry nose, decreases in hematocrit, hemoglobin, and erythrocyte count, an increase in ALP, an increase in liver weight, and white matter vacuolation of the central nervous system in males and females, and an increase in total cholesterol in males were observed at 50 mg/kg/day (within the range for Category 2) (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)). (7) As a result of a 21-day dermal toxicity test with rats, increases in AST and total cholesterol, and centrilobular hepatocyte hypertrophy in males, and dermatitis with ulcer in females were observed at or above 10 mg/kg/day (converted guidance value: 2.3 mg/kg/day, within the range for Category 1) (Risk Assessment Report (Pesticides) (Food Safety Commission of Japan, 2019)).
10	Aspiration hazard	Classification not possible	- -	-	-	[Rationale for the Classification] Classification not possible due to lack of data.

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification
11	Hazardous to the aquatic environment Short term (Acute)	-	- -	-	-	-
11	Hazardous to the aquatic environment Long term (Chronic)	-	- -	-	-	-
12	Hazardous to the ozone layer	-	- -	-	-	-

NOTE:

GHS Classification Result by the Japanese Government is intended to provide a reference for preparing a GHS label or SDS for users. To include the same classification result in a label or SDS for Japan is NOT mandatory.
Users can cite or copy this classification result when preparing a GHS label or SDS. Please be aware, however, that the responsibility for a label or SDS prepared by citing or copying this classification result lies with users.
This GHS classification was conducted based on the information sources and the guidance for classification and judgement which are described in the GHS Classification Guidance for the Japanese Government etc. Using other literature, test results etc. as evidence and including different content from this classification result in a label or SDS are allowed.
Hazard statement and precautionary statement will show by hovering the mouse cursor over a code in the column of "Hazard statement" and "Precautionary statement," respectively. In the excel file, both the codes and statements are provided.
A blank or "-" in the column of "Classification" denotes that a classification for the hazard class was not conducted in the year.
An asterisk “*” in the column of “Classification” denotes that “Not classified (or No applicable)” and/or “Classification not possible” is applicable. Details are described in the column of “Rationale for the classification”. If no English translation is available for “Rationale for the classification,” please refer to the Japanese version of the results.

To GHS Information