Item | Information |
---|---|
CAS RN | 35554-44-0 |
Chemical Name | (RS)-1-(beta-allyloxy-2,4-dichlorophenethyl)imidazole (synonym: Imazalil) |
Substance ID | R03-C-044-MHLW |
Classification year (FY) | FY2021 |
Ministry who conducted the classification | Ministry of Health, Labour and Welfare (MHLW) |
New/Revised | Revised |
Classification result in other fiscal year | FY2008 |
Download of Excel format | Excel file |
Item | Information |
---|---|
Guidance used for the classification (External link) | GHS Classification Guidance for the Japanese Government (FY2019 revised edition (Ver. 2.0)) |
UN GHS document (External link) | UN GHS document |
Definitions/Abbreviations (Excel file) | Definitions/Abbreviations |
Model Label by MHLW (External link) | MHLW Website (in Japanese Only) |
Model SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
OECD/eChemPortal (External link) | eChemPortal |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
1 | Explosives | - |
- |
- | - | - |
2 | Flammable gases | - |
- |
- | - | - |
3 | Aerosols | - |
- |
- | - | - |
4 | Oxidizing gases | - |
- |
- | - | - |
5 | Gases under pressure | - |
- |
- | - | - |
6 | Flammable liquids | - |
- |
- | - | - |
7 | Flammable solids | - |
- |
- | - | - |
8 | Self-reactive substances and mixtures | - |
- |
- | - | - |
9 | Pyrophoric liquids | - |
- |
- | - | - |
10 | Pyrophoric solids | - |
- |
- | - | - |
11 | Self-heating substances and mixtures | - |
- |
- | - | - |
12 | Substances and mixtures which, in contact with water, emit flammable gases | - |
- |
- | - | - |
13 | Oxidizing liquids | - |
- |
- | - | - |
14 | Oxidizing solids | - |
- |
- | - | - |
15 | Organic peroxides | - |
- |
- | - | - |
16 | Corrosive to metals | - |
- |
- | - | - |
17 | Desensitized explosives | - |
- |
- | - | - |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Category 3 |
Danger |
H301 | P301+P310 P264 P270 P321 P330 P405 P501 |
[Rationale for the Classification] Based on (1) to (3), it was classified in Category 3. Besides, the classification result was changed by adopting the category with the higher hazard. [Evidence Data] (1) LD50 for rats (males): 343 mg/kg (OECD TG401) (DFG MAK (2013), EU FESA (2007), CLH Report (2012), JMPR (2018)) (2) LD50 for rats (females): 227 mg/kg (OECD TG401) (DFG MAK (2013), EU FESA (2007), CLH Report (2012), JMPR (2018)) (3) LD50 for rats: 664 mg/kg (DFG MAK (2013), EU FESA (2007), JMPR (2018)) [Reference Data, etc.] (4) This substance was classified in Category 3 in the EU CLH. |
1 | Acute toxicity (Dermal) | Not classified |
- |
- | - | [Rationale for the Classification] Based on (1) to (4), it was classified as "Not classified" (Category 5 in UN GHS classification). [Evidence Data] (1) LD50 for rabbits: > 2,000 mg/kg (DFG MAK (2013), CLH Report (2012), JMPR (2018)) (2) LD50 for rats: > 2,000 mg/kg (DFG MAK (2013), JMPR (2018)) (3) LD50 for rats: 4,880 mg/kg (JMPR (2018)) (4) LD50 for rats: 4,200 mg/kg (JMPR (2018), NIOSH in Pubchem (Accessed Dec. 2021)) |
1 | Acute toxicity (Inhalation: Gases) | Not classified |
- |
- | - | [Rationale for the Classification] Solid (GHS definition). It was classified as "Not classified." |
1 | Acute toxicity (Inhalation: Vapours) | Classification not possible |
- |
- | - | [Rationale for the Classification] Classification not possible due to lack of data. |
1 | Acute toxicity (Inhalation: Dusts and mists) | Category 4 |
Warning |
H332 | P304+P340 P261 P271 P312 |
[Rationale for the Classification] Based on (1), it was classified in Category 4. [Evidence Data] (1) LC50 for rats: 2.43 mg/L (2.88 mg/L (males), 1.84 mg/L (females)) (CLH Report (2012), JMPR (2018), DFG MAK (2013)) |
2 | Skin corrosion/irritation | - |
- |
- | - | - |
3 | Serious eye damage/eye irritation | - |
- |
- | - | - |
4 | Respiratory sensitization | - |
- |
- | - | - |
4 | Skin sensitization | - |
- |
- | - | - |
5 | Germ cell mutagenicity | - |
- |
- | - | - |
6 | Carcinogenicity | - |
- |
- | - | - |
7 | Reproductive toxicity | - |
- |
- | - | - |
8 | Specific target organ toxicity - Single exposure | - |
- |
- | - | - |
9 | Specific target organ toxicity - Repeated exposure | - |
- |
- | - | - |
10 | Aspiration hazard | - |
- |
- | - | - |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | |
---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment Short term (Acute) | - |
- |
- | - | - |
11 | Hazardous to the aquatic environment Long term (Chronic) | - |
- |
- | - | - |
12 | Hazardous to the ozone layer | - |
- |
- | - | - |
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