Item | Information |
---|---|
CAS RN | 16923-58-3 |
Chemical Name | Disodium hexachloroplatinate |
Substance ID | m-nite-16923-58-3_v1 |
Download of Excel format | Excel file |
Item | Information |
---|---|
Guidance used for the classification (External link) | To Guidance List |
UN GHS document (External link) | To UN GHS document |
FAQ(GHS classification results by the Japanese Government) | To FAQ |
List of Information Sources (Excel file) | List of Information Sources |
List of Definitions/Abbreviations | Definitions/Abbreviations |
Sample Label by MHLW (External link) | MHLW Website (in Japanese Only) |
Sample SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
OECD/eChemPortal (External link) | To OECD/eChemPortal (External link) |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
1 | Explosives | Not classified (Not applicable) |
- |
- | - | There are no chemical groups associated with explosive properties present in the molecule. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
2 | Flammable gases | Not classified (Not applicable) |
- |
- | - | "Solids" according to GHS definition. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
3 | Aerosols | Not classified (Not applicable) |
- |
- | - | Not an aerosol product. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
4 | Oxidizing gases | Not classified (Not applicable) |
- |
- | - | "Solids" according to GHS definition. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
5 | Gases under pressure | Not classified (Not applicable) |
- |
- | - | "Solids" according to GHS definition. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
6 | Flammable liquids | Not classified (Not applicable) |
- |
- | - | "Solids" according to GHS definition. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
7 | Flammable solids | Not classified |
- |
- | - | It was classified as "Not classified" from the information that it is a non-combustible solid (GESTIS (Access on June. 2011)). | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
8 | Self-reactive substances and mixtures | Not classified (Not applicable) |
- |
- | - | There are no chemical groups present in the molecule associated with explosive or self-reactive properties. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
9 | Pyrophoric liquids | Not classified (Not applicable) |
- |
- | - | "Solids" according to GHS definition. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
10 | Pyrophoric solids | Not classified |
- |
- | - | It was classified as "Not classified" from the information that it is a non-combustible solid (GESTIS (Access on June. 2011)). | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
11 | Self-heating substances and mixtures | Not classified |
- |
- | - | It was classified as "Not classified" from the information that it is a non-combustible solid (GESTIS (Access on June. 2011)). | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified |
- |
- | - | It contains a metal (Pt), but it is conceivable that it is stable as an aqueous solution from water solubility data (53 g/100 g (16 degrees C) (CRC (91st, 2010)). Therefore, it was classified as "Not classified." |
FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
13 | Oxidizing liquids | Not classified (Not applicable) |
- |
- | - | "Solids" according to GHS definition. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
14 | Oxidizing solids | Classification not possible |
- |
- | - | An inorganic compound that contains chlorine has no data. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
15 | Organic peroxides | Not classified (Not applicable) |
- |
- | - | It is an inorganic compound. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
16 | Corrosive to metals | Classification not possible |
- |
- | - | No established test method suitable for solid substances. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
17 | Desensitized explosives | - |
- |
- | - | - | - | - |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Category 2 |
Danger |
H300 | P301+P310 P264 P270 P321 P330 P405 P501 |
It was classified in Category 2 from a reported LD50 value of 20 to 50 mg/kg for rats (EHC 125 (1991)). Besides, it is classified in T; R25 in EU classification (EC-JRC (ESIS) (Access on July. 2011)). |
FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
1 | Acute toxicity (Dermal) | Classification not possible |
- |
- | - | No data. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
1 | Acute toxicity (Inhalation: Gases) | Not classified (Not applicable) |
- |
- | - | It is a solid at normal temperatures. (Merck (14th, 2006)) | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
1 | Acute toxicity (Inhalation: Vapours) | Classification not possible |
- |
- | - | No data. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible |
- |
- | - | No data. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
2 | Skin corrosion/irritation | Not classified |
- |
- | - | Because a skin irritation test using rabbits (US Federal Register 1973 Skin Test) reported it is "mild irritant" from a primary irritation index of 0.5 (EHC 125 (1991)), it was classified as "Not classified" in JIS classification (Category 3 in UN GHS classification). | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
3 | Serious eye damage/eye irritation | Category 2 |
Warning |
H319 | P305+P351+P338 P337+P313 P264 P280 |
From an "irritant" result in an eye irritation test using rabbits (US Federal Register 1973 Eye Test) (EHC 125 (1991)), it was classified in Category 2. It is classified in Xi; R41 in EU classification (EC-JRC (ESIS) (Access on July 2011)). Besides, there is the information that a soluble platinum compound is corrosive to eyes (Netherlands evaluation document (2008), corresponding to List 2). |
FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
4 | Respiratory sensitization | Category 1A |
Danger |
H334 | P304+P340 P342+P311 P261 P284 P501 |
Platinum itself or its compound is designated as a sensitizing substance (respiratory tract; Group 1) in Japan Society for Occupational Health (Journal of Occupational Health, Vol.52 (2010)). In addition, it was reported that severe deficits in pulmonary function in comparison with a control group were observed at a concentration of 200 micro g/m3 by a provocation treatment 2 weeks after biweekly inhalation exposure (an induction period) to monkeys for 12 weeks (EHC 125 (1991)), furthermore, an acute asthmatic seizure occurred in guinea pigs by an inhalation exposure to this substance (PATTY (5th, 2001)). From the above, it was classified in Category 1A. Besides, this substance is classified in R42/43 in EU classification (EC-JRC (ESIS) (Access on July 2011)). |
FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
4 | Skin sensitization | Category 1A |
Warning |
H317 | P302+P352 P333+P313 P362+P364 P261 P272 P280 P321 P501 |
In auricular lymph node test in mice (ANA method), numbers of auricular lymph node cells increased four times, and proliferating cell ratio in auricular lymph node cells in dosed groups increased more than 20 times. (Netherlands evaluation document (2008)) In a local lymph node test in mice (LLNA method), a total number of lymph node cells in a high concentration group (2.5%) increased about three times, and an average SI value was 2.6 +/- 1.0. (Netherlands evaluation document (2008)) It was classified in Category 1A because platinum itself or its compound is designated as a sensitizing substance (skin; Group 1) in Japan Society for Occupational Health (Journal of Occupational Health, Vol.52 (2010)) despite the SI value of less than 3 in the LLNA method. Besides, it is classified in R42/43 in EU classification (EC-JRC (ESIS) (Access on July 2011)). |
FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
5 | Germ cell mutagenicity | Classification not possible |
- |
- | - | No data. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
6 | Carcinogenicity | Classification not possible |
- |
- | - | No data. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
7 | Reproductive toxicity | Classification not possible |
- |
- | - | No data. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
8 | Specific target organ toxicity - Single exposure | Category 3 (Respiratory tract irritation) |
Warning |
H335 | P304+P340 P403+P233 P261 P271 P312 P405 P501 |
It was classified in Category 3 (respiratory tract irritation) because it was reported that a result of an inhalation test to dust of this substance in a cynomolgus monkey showed that this substance is a primary irritant to respiratory tract causing bronchoconstriction (Netherlands evaluation document (2008)). | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
9 | Specific target organ toxicity - Repeated exposure | Classification not possible |
- |
- | - | No data. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
10 | Aspiration hazard | Classification not possible |
- |
- | - | No data. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment Short term (Acute) | Classification not possible |
- |
- | - | No data. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
11 | Hazardous to the aquatic environment Long term (Chronic) | Classification not possible |
- |
- | - | No data. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
12 | Hazardous to the ozone layer | Classification not possible |
- |
- | - | This substance is not listed in Annexes to the Montreal Protocol. | FY2011 | GHS Classification Guidance by the Japanese Government (July, 2010) |
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