Latest GHS Classification Results by the Japanese Government (edited by NITE)

Japanese



GENERAL INFORMATION
 
Item Information
CAS RN 2610-05-1
Chemical Name Disodium 6,6'-[(3,3'-Dimethoxy-4,4'-biphenylylene)bisazo]bis(4-amino-5-hydroxy-1,3-naphthalenedisulfonate); C.I. Direct Blue 1
Substance ID m-nite-2610-05-1_v1
Download of Excel format Excel file

REFERENCE INFORMATION
Item Information
Guidance used for the classification (External link) To Guidance List
UN GHS document (External link) To UN GHS document
FAQ（GHS classification results by the Japanese Government） To FAQ
List of Information Sources (Excel file) List of Information Sources
List of Definitions/Abbreviations Definitions/Abbreviations
Sample Label by MHLW (External link) MHLW Website (in Japanese Only)
Sample SDS by MHLW (External link) MHLW Website (in Japanese Only)
OECD/eChemPortal (External link) To OECD/eChemPortal (External link)

PHYSICAL HAZARDS
Hazard class Classification Pictogram
Signal word 		Hazard statement
(code) 		Precautionary statement
(code) 		Rationale for the classification Classification year (FY) GHS Classification Guidance for the Japanese Government
1 Explosives Not classified (Not applicable)
-
-
- - There are no chemical groups associated with explosive properties present in the molecules. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
2 Flammable gases Not classified (Not applicable)
-
-
- - Solid FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
3 Aerosols Not classified (Not applicable)
-
-
- - Not aerosol products. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
4 Oxidizing gases Not classified (Not applicable)
-
-
- - Solid FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
5 Gases under pressure Not classified (Not applicable)
-
-
- - Solid FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
6 Flammable liquids Not classified (Not applicable)
-
-
- - Solid FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
7 Flammable solids Classification not possible
-
-
- - No data available. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
8 Self-reactive substances and mixtures Not classified (Not applicable)
-
-
- - There are no chemical groups present in the molecule associated with explosive or self-reactive properties. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
9 Pyrophoric liquids Not classified (Not applicable)
-
-
- - Solid FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
10 Pyrophoric solids Classification not possible
-
-
- - No data available. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
11 Self-heating substances and mixtures Classification not possible
-
-
- - No data available. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified (Not applicable)
-
-
- - The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At). FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
13 Oxidizing liquids Not classified (Not applicable)
-
-
- - Solid FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
14 Oxidizing solids Classification not possible
-
-
- - Classification not possible due to lack of data. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
15 Organic peroxides Not classified (Not applicable)
-
-
- - Organic compounds containing no bivalent -O-O- structure FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
16 Corrosive to metals Classification not possible
-
-
- - No data available. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
17 Desensitized explosives -
-
-
- - - - -

HEALTH HAZARDS
Hazard class Classification Pictogram
Signal word 		Hazard statement
(code) 		Precautionary statement
(code) 		Rationale for the classification Classification year (FY) GHS Classification Guidance for the Japanese Government
1 Acute toxicity (Oral) Classification not possible
-
-
- - No data available. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
1 Acute toxicity (Dermal) Classification not possible
-
-
- - No data available. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
1 Acute toxicity (Inhalation: Gases) Not classified (Not applicable)
-
-
- - Since the substance is a solid, it was classified into the "Not applicable" category. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
1 Acute toxicity (Inhalation: Vapours) Classification not possible
-
-
- - No data available. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible
-
-
- - No data available. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
2 Skin corrosion/irritation Category 3
-
Warning
- - Since C.I. Direct Blue 1 (CAS: 2610-05-1) is reported to cause mild irritation in humans (HSDB, 2003), it was classified into Category 3. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
3 Serious eye damage/eye irritation Category 2A


Warning
H319 P305+P351+P338
P337+P313
P264
P280 		Since C.I. Direct Blue 1 (CAS: 2610-05-1) is reported to cause moderate eye irritation in rabbits (HSDB, 2003), it was classified into Category 2A to 2B. More refined categorization is difficult. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
4 Respiratory sensitization Classification not possible
-
-
- - No data available. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
4 Skin sensitization Not classified
-
-
- - Since C.I. Direct Blue 1 (CAS: 2610-05-1) was found to not be skin sensitizing in guinea pigs and humans, it was classified into the "Not classified" category. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
5 Germ cell mutagenicity Classification not possible
-
-
- - No data available. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
6 Carcinogenicity Category 1B


Danger
H350 P308+P313
P201
P202
P280
P405
P501 		Dyes metabolized to 3,3'-dimethoxybenzidine are rated as "R" by the U.S. NTP (2005), and o-dianisidine-based azo dyes are rated as "Carc. Cat. 2" by the EU (2007). Based on these ratings, the substance was classified into Category 1B. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
7 Reproductive toxicity Category 2


Warning
H361 P308+P313
P201
P202
P280
P405
P501 		Pregnant rats that received an intraperitoneal injection of C.I. Direct Blue 1 (CAS: 2610-05-1) showed increases in resorptions and increases in number of malformed fetuses (RTECS, accessed in October 2007; HSDB, 2003). The effect of C.I. Direct Blue 1 on parental animals is not clear. Based on this information, the substance was classified into Category 2. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
8 Specific target organ toxicity - Single exposure Classification not possible
-
-
- - No data available. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
9 Specific target organ toxicity - Repeated exposure Classification not possible
-
-
- - No data available. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
10 Aspiration hazard Classification not possible
-
-
- - No data available. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）

ENVIRONMENTAL HAZARDS
Hazard class Classification Pictogram
Signal word 		Hazard statement
(code) 		Precautionary statement
(code) 		Rationale for the classification Classification year (FY) GHS Classification Guidance for the Japanese Government
11 Hazardous to the aquatic environment Short term (Acute) Classification not possible
-
-
- - No data available. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
11 Hazardous to the aquatic environment Long term (Chronic) Classification not possible
-
-
- - No data available. FY2007 GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
12 Hazardous to the ozone layer -
-
-
- - - - -


NOTE:
  • GHS Classification Result by the Japanese Government is intended to provide a reference for preparing a GHS label or SDS for users. To include the same classification result in a label or SDS for Japan is NOT mandatory.
  • Users can cite or copy this classification result when preparing a GHS label or SDS. Please be aware, however, that the responsibility for a label or SDS prepared by citing or copying this classification result lies with users.
  • This GHS classification was conducted based on the information sources and the guidance for classification and judgement which are described in the GHS Classification Guidance for the Japanese Government etc. Using other literature, test results etc. as evidence and including different content from this classification result in a label or SDS are allowed.
  • Hazard statement and precautionary statement will show by hovering the mouse cursor over a code in the column of "Hazard statement" and "Precautionary statement," respectively. In the excel file, both the codes and statements are provided.
  • A blank or "-" in the column of "Classification" denotes that a classification for the hazard class was not conducted in the year.
  • An asterisk “*” in the column of “Classification” denotes that “Not classified (or No applicable)” and/or “Classification not possible” is applicable. Details are described in the column of “Rationale for the classification”. If no English translation is available for “Rationale for the classification,” please refer to the Japanese version of the results.

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