NITE - Chemical Management Field

Latest GHS Classification Results by the Japanese Government (edited by NITE)

GENERAL INFORMATION

Item	Information
CAS RN	31093-47-7
Chemical Name	Decylbenzenesulfonic acid (C10)
Substance ID	m-nite-31093-47-7_v1
Download of Excel format	Excel file

REFERENCE INFORMATION

Item	Information
Guidance used for the classification (External link)	To Guidance List
UN GHS document (External link)	To UN GHS document
FAQ（GHS classification results by the Japanese Government）	To FAQ
List of Information Sources (Excel file)	List of Information Sources
List of Definitions/Abbreviations	Definitions/Abbreviations
Sample Label by MHLW (External link)	MHLW Website (in Japanese Only)
Sample SDS by MHLW (External link)	MHLW Website (in Japanese Only)
OECD/eChemPortal (External link)	To OECD/eChemPortal (External link)

PHYSICAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
1	Explosives	Not classified (Not applicable)	- -	-	-	Containing no chemical groups with explosive properties	FY2006	GHS Classification Manual （10 Feb, 2006）
2	Flammable gases	Not classified (Not applicable)	- -	-	-	Classified as "liquid" or "solid" according to GHS definition	FY2006	GHS Classification Manual （10 Feb, 2006）
3	Aerosols	Not classified (Not applicable)	- -	-	-	Not aerosol products	FY2006	GHS Classification Manual （10 Feb, 2006）
4	Oxidizing gases	Not classified (Not applicable)	- -	-	-	Classified as "liquid" or "solid" according to GHS definition	FY2006	GHS Classification Manual （10 Feb, 2006）
5	Gases under pressure	Not classified (Not applicable)	- -	-	-	Classified as "liquid" or "solid" according to GHS definition	FY2006	GHS Classification Manual （10 Feb, 2006）
6	Flammable liquids	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
7	Flammable solids	Classification not possible	- -	-	-	Classified into Class 8 (UN#2585 Alkyl sulfonic acids (solid) or Aryl sulfonic acids (solid) (with not more than 5% free sulfuric acid)) (UN Recommendation on the Transport of Dangerous Goods).	FY2006	GHS Classification Manual （10 Feb, 2006）
8	Self-reactive substances and mixtures	Not classified	- -	-	-	No data available, though being sulfonyls, containing chemical groups with self-reactive properties. Classified into Class 8 (UN#2585 Alkyl sulfonic acids (solid) or Aryl sulfonic acids (liquid) (with not more than 5% free sulfuric acid), UN#2586 Alkyl sulfonic acids (liquid) or Aryl sulfonic acids (liquid) (with not more than 5% free sulfuric acid)) (UN Recommendation on the Transport of Dangerous Goods).	FY2006	GHS Classification Manual （10 Feb, 2006）
9	Pyrophoric liquids	Classification not possible	- -	-	-	Classified into Class 8 (UN#2586 Alkyl sulfonic acids (liquid) or Aryl sulfonic acids (liquid) (with not more than 5% free sulfuric acid)) (UN Recommendation on the Transport of Dangerous Goods).	FY2006	GHS Classification Manual （10 Feb, 2006）
10	Pyrophoric solids	Classification not possible	- -	-	-	Classified into Class 8 (UN#2585 Alkyl sulfonic acids (solid) or Aryl sulfonic acids (solid) (with not more than 5% free sulfuric acid)) (UN Recommendation on the Transport of Dangerous Goods).	FY2006	GHS Classification Manual （10 Feb, 2006）
11	Self-heating substances and mixtures	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
12	Substances and mixtures which, in contact with water, emit flammable gases	Not classified (Not applicable)	- -	-	-	Containing no metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At)	FY2006	GHS Classification Manual （10 Feb, 2006）
13	Oxidizing liquids	Not classified	- -	-	-	No data available, though being organic compounds containing oxygen bound to the elements other than carbon and hydrogen. Classified intoo Class 8 (UN#2586 Alkyl sulfonic acids (liquid) or Aryl sulfonic acids (liquid) (with not more than 5% free sulfuric acid)) (UN Recommendation on the Transport of Dangerous Goods).	FY2006	GHS Classification Manual （10 Feb, 2006）
14	Oxidizing solids	Not classified	- -	-	-	Organic compounds containing oxygen bound to the elements other than carbon and hydrogen. Classified into Class 8 (UN#2585 Alkyl sulfonic acids (solid) or Aryl sulfonic acids (solid) (with not more than 5% free sulfuric acid)) (UN Recommendation on the Transport of Dangerous Goods).	FY2006	GHS Classification Manual （10 Feb, 2006）
15	Organic peroxides	Not classified (Not applicable)	- -	-	-	Organic compounds containing no "-O-O-" structure	FY2006	GHS Classification Manual （10 Feb, 2006）
16	Corrosive to metals	Classification not possible	- -	-	-	Classification not possible due to lack of data. Classified into "Corrosive Substances" by the UN Recommendations on the Transport of Dangerous Goods. However, the category includes skin corrosivity, and it is unclear whether the substance is classified as "metal" corrosive (UN#2585 Alkyl sulfonic acids (solid) or Aryl sulfonic acids (solid) (with not more than 5% free sulfuric acid), UN#2586 Alkyl sulfonic acids (liquid) or Aryl sulfonic acids (liquid) (with not more than 5% free sulfuric acid)).	FY2006	GHS Classification Manual （10 Feb, 2006）
17	Desensitized explosives	-	- -	-	-	-	-	-

HEALTH HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
1	Acute toxicity (Oral)	Category 4	Warning	H302	P301+P312 P264 P270 P330 P501	Based on the LD50 value of 502mg/kg calculated from the testing data of rat LD50 (oral route) of 404mg/kg (males), 409mg/kg (females), 659mg/kg (males), 670mg/kg (females), 760mg/kg (females) and 873mg/kg (males) (CERI-NITE Hazard Assessment No.5 (2005)) (LAS mixtures with carbon chain lengths of 10-14; no data available on decylbenzene sulfonic acid per se).	FY2006	GHS Classification Manual （10 Feb, 2006）
1	Acute toxicity (Dermal)	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
1	Acute toxicity (Inhalation: Gases)	Not classified (Not applicable)	- -	-	-	Due to the fact that the substance is "liquid" or "solid"according to the GHS definition and inhalation of its gas is not expected.	FY2006	GHS Classification Manual （10 Feb, 2006）
1	Acute toxicity (Inhalation: Vapours)	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
1	Acute toxicity (Inhalation: Dusts and mists)	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
2	Skin corrosion/irritation	Category 2	Warning	H315	P302+P352 P332+P313 P362+P364 P264 P280 P321	Based on the description in the report on human epidemiological studies (CERI-NITE Hazard Assessment No.5 (2005)): "24 hour application of 1% aqueous solution of LAS induced moderate irritation." The substance is thus considered a moderate irritant (LAS mixtures with carbon chain lengths of 10-14; no data available on decylbenzene sulfonic acid per se).	FY2006	GHS Classification Manual （10 Feb, 2006）
3	Serious eye damage/eye irritation	Category 2B	- Warning	H320	P305+P351+P338 P337+P313 P264	Based on the description in the report on rabbit eye irritation tests (CERI-NITE Hazard Assessment No.5 (2005)): "LAS concentrations of 0.5% or greater produced severe congestion and lacrimation with edema in rabbit eyes, which persisted for 24 hours but cleared up within 3 days." The substance is thus considered a mild irritant (LAS mixtures with carbon chain lengths of 10-14; no data available on decylbenzene sulfonic acid per se).	FY2006	GHS Classification Manual （10 Feb, 2006）
4	Respiratory sensitization	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
4	Skin sensitization	Not classified	- -	-	-	There is one positive result in the maximization test employing guinea pig. However, it is judged as negative to humans based on two negative results in the same maximization test indicated in OECD SIDS, one negative result in the buehler test, and two negative results in the controlled or large-scale human repetition patch test. Therefore, skin sensitization is corrected from "Category 1" to "Not classified."	FY2007	GHS Classification Manual （10 Feb, 2006）/Technical Guidance Document on the GHS Classification （6 Dec, 2005）
5	Germ cell mutagenicity	Classification not possible	- -	-	-	Classification not possible due to the insufficiency of data (no definite data are available regarding decylbenzene sulfonic acid per se). As for linear alkylbenzene sulphonate (LAS) and its salts [carbon chain lengths of 10-14 and their mixtures], no data are available on germ cell mutagenicity tests in vivo, whereas multi-generation mutagenicity tests (dominant lethal tests), somatic cell mutagenicity tests in vivo (micronucleus tests, chromosome aberration tests) and Ames assay gave negative results, described in NTP DB (Access on June, 2006), CERI-NITE Hazard Assessment No.5 (2005) and EHC 169 (1996).	FY2006	GHS Classification Manual （10 Feb, 2006）
6	Carcinogenicity	Classification not possible	- -	-	-	Classification not possible based on expert judgment in the absence of existing classification together with the absence of definite data on decylbenzene sulfonic acid per se. CERI-NITE Hazard Assessment No.5 (2005) presents some data regarding carcinogenicity studies on linear alkylbenzene sulphonate (LAS) and its salts [carbon chain lengths of 10-14 and their mixtures].	FY2006	GHS Classification Manual （10 Feb, 2006）
7	Reproductive toxicity	Classification not possible	- -	-	-	Classification not possible due to the insufficiency of data (no definite data are available on decylbenzene sulfonic acid per se). As for linear alkylbenzene sulphonate (LAS) and its salts [carbon chain lengths of 10-14 and their mixtures], there was no evidence of adverse effects on the parental animals and the offspring observed in oral studies, whereas decreased fertility and increased incidence of malformation in the offspring were observed at doses inducing parental toxicity in dermal studies, described in CERI-NITE Hazard Assessment No.5 (2005) and EHC 169 (1996).	FY2006	GHS Classification Manual （10 Feb, 2006）
8	Specific target organ toxicity - Single exposure	Classification not possible	- -	-	-	Classification not possible in the absence of data on decylbenzene sulfonic acid per se. Note: As for linear alkylbenzene sulphonate (LAS) and its salts [carbon chain lengths of 10-14 and their mixtures], "clinical symptoms include confusion, vomiting, pharyngal and oral pains, and the tendency of blood pressure to decrease" (NITE Initial Risk Assessment No.5 (2005)).	FY2006	GHS Classification Manual （10 Feb, 2006）
9	Specific target organ toxicity - Repeated exposure	Classification not possible	- -	-	-	Classification not possible due to the fact that the only available data are those for mixtures of C10-14.	FY2006	GHS Classification Manual （10 Feb, 2006）
10	Aspiration hazard	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
11	Hazardous to the aquatic environment Short term (Acute)	Category 2	- -	H401	P273 P501	It was classified into Category 2 from 48 hours LC50=9.55mg/L of the crustacea (Daphnia magna) (EHC169 (1996) and others.). [NOTE]Since it may show same behavior of sodium salt in the environment, it was classified by the data of sodium decylbenzenesulfonate(C10).	FY2006	GHS Classification Manual （10 Feb, 2006）
11	Hazardous to the aquatic environment Long term (Chronic)	Not classified	- -	-	-	Since there was rapidly degrading (the decomposition of p-n-dodecylbenzenesulfonic acid sodium salt by BOD: 73% (Existing Chemical Safety Inspections Data)) and the bio-accumulation was low (log Kow=2.02(PHYSPROP Database, 2005)), it was claasified into Not classified. [NOTE]Since it may show same behavior of sodium salt in the environment, it was classified by the data of sodium dodecylbenzenesulfonate(C10).	FY2006	GHS Classification Manual （10 Feb, 2006）
12	Hazardous to the ozone layer	-	- -	-	-	-	-	-

NOTE:

GHS Classification Result by the Japanese Government is intended to provide a reference for preparing a GHS label or SDS for users. To include the same classification result in a label or SDS for Japan is NOT mandatory.
Users can cite or copy this classification result when preparing a GHS label or SDS. Please be aware, however, that the responsibility for a label or SDS prepared by citing or copying this classification result lies with users.
This GHS classification was conducted based on the information sources and the guidance for classification and judgement which are described in the GHS Classification Guidance for the Japanese Government etc. Using other literature, test results etc. as evidence and including different content from this classification result in a label or SDS are allowed.
Hazard statement and precautionary statement will show by hovering the mouse cursor over a code in the column of "Hazard statement" and "Precautionary statement," respectively. In the excel file, both the codes and statements are provided.
A blank or "-" in the column of "Classification" denotes that a classification for the hazard class was not conducted in the year.
An asterisk “*” in the column of “Classification” denotes that “Not classified (or No applicable)” and/or “Classification not possible” is applicable. Details are described in the column of “Rationale for the classification”. If no English translation is available for “Rationale for the classification,” please refer to the Japanese version of the results.

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