Item | Information |
---|---|
CAS RN | 3926-62-3 |
Chemical Name | Sodium chloroacetate |
Substance ID | m-nite-3926-62-3_v1 |
Download of Excel format | Excel file |
Item | Information |
---|---|
Guidance used for the classification (External link) | To Guidance List |
UN GHS document (External link) | To UN GHS document |
FAQ(GHS classification results by the Japanese Government) | To FAQ |
List of Information Sources (Excel file) | List of Information Sources |
List of Definitions/Abbreviations | Definitions/Abbreviations |
Sample Label by MHLW (External link) | MHLW Website (in Japanese Only) |
Sample SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
OECD/eChemPortal (External link) | To OECD/eChemPortal (External link) |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
1 | Explosives | Not classified (Not applicable) |
- |
- | - | There are no chemical groups associated with explosive properties present in the molecules. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
2 | Flammable gases | Not classified (Not applicable) |
- |
- | - | Solid (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
3 | Aerosols | Not classified (Not applicable) |
- |
- | - | Not aerosol products | FY2006 | GHS Classification Manual (10 Feb, 2006) |
4 | Oxidizing gases | Not classified (Not applicable) |
- |
- | - | Solid (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
5 | Gases under pressure | Not classified (Not applicable) |
- |
- | - | Solid (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
6 | Flammable liquids | Not classified (Not applicable) |
- |
- | - | Solid (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
7 | Flammable solids | Not classified |
- |
- | - | Although it is combustible, UNRTDG is classified into 6.1 and III according to the UNRTDG No. (2659). Since 4.1 was not assigned, it was classified as out of Category. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
8 | Self-reactive substances and mixtures | Not classified (Not applicable) |
- |
- | - | There are no chemical groups associated with explosive or self-reactive properties present in the molecule. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
9 | Pyrophoric liquids | Not classified (Not applicable) |
- |
- | - | Solid (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
10 | Pyrophoric solids | Not classified |
- |
- | - | Not classified because of UNRTDG No. 2659, Class: 6.1, III (not Class: 4.2) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
11 | Self-heating substances and mixtures | Not classified |
- |
- | - | Not classified because of UNRTDG No. 2659 Class: 6.1, PG III (not Class: 4.2) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified |
- |
- | - | Stable to water (the water solubility is obtained) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
13 | Oxidizing liquids | Not classified (Not applicable) |
- |
- | - | Solid (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
14 | Oxidizing solids | Not classified |
- |
- | - | UNRTDG No. 2659, Class: 6.1; PG III (Not 5.1). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
15 | Organic peroxides | Not classified (Not applicable) |
- |
- | - | Organic compounds containing no -0-0- structure | FY2006 | GHS Classification Manual (10 Feb, 2006) |
16 | Corrosive to metals | Classification not possible |
- |
- | - | Test methods applicable to solid substances are not available. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
17 | Desensitized explosives | - |
- |
- | - | - | - | - |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Category 4 |
Warning |
H302 | P301+P312 P264 P270 P330 P501 |
The substance was classified as Category 4 baced on the LD50=386mg/kg which was calculated from the rat LD50s: 335mg/kg, 474mg/kg, 580mg/kg and 487mg/kg (SIDS, 1996) . | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Dermal) | - |
Warning |
- | - | It was set as Category 5 based on rat LD50 value >2000mg/kg (SIDS, 1996). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Inhalation: Gases) | Not classified (Not applicable) |
- |
- | - | Solid (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Inhalation: Vapours) | Not classified (Not applicable) |
- |
- | - | Since there was description that there is almost no vapor pressures at 25degC (ICSC (J) (2003)), it was out of classification. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
2 | Skin corrosion/irritation | Not classified |
- |
- | - | There is a report that skin irritation was not indicated in the rabbit (SIDS (1996)), and it carried out the outside of Category. In addition, the data which is supported was not found although it was considered as those with skin irritation (Xi;R38) in EU-Annex I (Access on June 2005). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
3 | Serious eye damage/eye irritation | Category 2B |
Warning |
H320 | P305+P351+P338 P337+P313 P264 |
Although SIDS (1996) had one positive report and one negative report in the eye irritation tests in rabbit, in ICSC (J) (2003) having description which stimulates the eye (redness, pain, haze eyes). So it is considered that it irritates to the eye mildly, it was classified into Category 2B. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
4 | Respiratory sensitization | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
4 | Skin sensitization | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
5 | Germ cell mutagenicity | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
6 | Carcinogenicity | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
7 | Reproductive toxicity | Category 2 |
Warning |
H361 | P308+P313 P201 P202 P280 P405 P501 |
In the teratogenicity study of the rat of SIDS (1996) of Priority 1 document, a fetal heart abnormality was increasing intentionally by the dose as which general toxicity (inhibitation of weight gains) is regarded to dam. So it was set as Category 2. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
8 | Specific target organ toxicity - Single exposure | Category 2 (central nervous system, heart, kidney), Category 3 (respiratory tract irritation) |
Warning |
H371 H335 |
P308+P311 P260 P264 P270 P405 P501 P304+P340 P403+P233 P261 P271 P312 |
It was considered as Category 2, (a central nervous system, heart, kidney), Category 3 (respiratory irritant) based on the description that it effects on central nervous system, heart and the kidney in human and stimulates respiratory tract in ICSC (J) (2003) of Priority 2 document. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
9 | Specific target organ toxicity - Repeated exposure | Category 2 (liver, kidney) |
Warning |
H373 | P260 P314 P501 |
Because of the effects that were confirmed on livers and kidneys in the repeats oral administration tests with rats (SIDS (1996) and RTECS (1997)), and of their toxicologic amount of findings respectively, it was classified into Category 2 (liver, kidney). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
10 | Aspiration hazard | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment Short term (Acute) | Not classified |
- |
- | - | It carried out the outside of Category from 24-hour LC50=800mg/L of Crustacea (Daphnia magna), and others (SIDS, 1996). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
11 | Hazardous to the aquatic environment Long term (Chronic) | Not classified |
- |
- | - | Since not water-insoluble (aqueous solubility =820000mg/L(SIDS, 1996)) and acute toxicity is low. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
12 | Hazardous to the ozone layer | - |
- |
- | - | - | - | - |
|