Item | Information |
---|---|
CAS RN | 505-32-8 |
Chemical Name | 3,7,11,15-Tetramethylhexadec-1-en-3-ol |
Substance ID | m-nite-505-32-8_v1 |
Download of Excel format | Excel file |
Item | Information |
---|---|
Guidance used for the classification (External link) | To Guidance List |
UN GHS document (External link) | To UN GHS document |
FAQ(GHS classification results by the Japanese Government) | To FAQ |
List of Information Sources (Excel file) | List of Information Sources |
List of Definitions/Abbreviations | Definitions/Abbreviations |
Sample Label by MHLW (External link) | To Workplace Safety Site (MHLW) |
Sample SDS by MHLW (External link) | To Workplace Safety Site (MHLW) |
OECD/eChemPortal (External link) | To OECD/eChemPortal (External link) |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
1 | Explosives | Not classified (Not applicable) |
- |
- | - | There are no chemical groups associated with explosive properties present in the molecules. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
2 | Flammable gases | Not classified (Not applicable) |
- |
- | - | Liquid | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
3 | Aerosols | Not classified (Not applicable) |
- |
- | - | Not aerosol products | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
4 | Oxidizing gases | Not classified (Not applicable) |
- |
- | - | Liquid | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
5 | Gases under pressure | Not classified (Not applicable) |
- |
- | - | Liquid | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
6 | Flammable liquids | Not classified |
- |
- | - | Since the flash point by IUCLID(2000) is 135degC(closed type), it was classified into Not classified. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
7 | Flammable solids | Not classified (Not applicable) |
- |
- | - | Liquid | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
8 | Self-reactive substances and mixtures | Not classified (Not applicable) |
- |
- | - | There are no chemical groups associated with explosive or self-reactive properties present in the molecule. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
9 | Pyrophoric liquids | Classification not possible |
- |
- | - | Classification not possible due to lack of data | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
10 | Pyrophoric solids | Not classified (Not applicable) |
- |
- | - | Liquid | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
11 | Self-heating substances and mixtures | Classification not possible |
- |
- | - | The test method suitable for liquid substances is not established. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified (Not applicable) |
- |
- | - | Metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At) are not included. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
13 | Oxidizing liquids | Not classified (Not applicable) |
- |
- | - | Although it is an organic compound including oxygen, not fluorine and chlorine, this oxygen has not chemically bound to any elements other than carbon and hydrogen. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
14 | Oxidizing solids | Not classified (Not applicable) |
- |
- | - | Liquid | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
15 | Organic peroxides | Not classified (Not applicable) |
- |
- | - | The organic compound not including peroxy group in molecule. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
16 | Corrosive to metals | Classification not possible |
- |
- | - | Classification not possible due to lack of data | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
17 | Desensitized explosives | - |
- |
- | - | - | - | - |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Not classified |
- |
- | - | It was classified into "Not classified" from >12,000 mg/kg which is the latest data among LD50 value >8,000 mg/kg, > 5,400 mg/kg, and >12,000 mg/kg (SIDS (2006)) of the oral administration test employing a rat. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
1 | Acute toxicity (Dermal) | Not classified |
- |
- | - | From a description of LD50 value of >5,000 mg/kg (SIDS (2006)) in the dermal administration test employing rabbits, it was classified into "Not classified". | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
1 | Acute toxicity (Inhalation: Gases) | Not classified (Not applicable) |
- |
- | - | Since it was a solid by the definition of GHS and inhalation in gas was not assumed, it was classified into "Not applicable". | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
1 | Acute toxicity (Inhalation: Vapours) | Classification not possible |
- |
- | - | Saturated vapor pressure level at 20degCis 0.03 ppm. Since it is written in SIDS (2006) that NOEC of the 8-hour inhalation exposure test employing guinea pig is 0.3 mg/m3 (equivalent 0.025 ppm), it is classified according to the gas standard. Therefore, since 4-hour equivalent LC50 value is >0.025 ppm, and the classification cannot be specified, classification is not possible. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible |
- |
- | - | Classification not possible due to lack of data | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
2 | Skin corrosion/irritation | Classification not possible |
- |
- | - | Although it has been described that moderate to severe irritation (SIDS (2006)) was determined in the skin irritation test with rabbits, the result was obtained by 24-hour dose. Moreover, although it has been described that no serious skin reaction (SIDS (2006)) was not triggered in the 48-hour dose study in human (27 volunteers), the tested concentration was 10%. As mentioned above, classification is not possible with no appropriate data. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
3 | Serious eye damage/eye irritation | Category 2B |
Warning |
H320 | P305+P351+P338 P337+P313 P264 |
There is a description that although mild redness and turbidity are seen 1 hour 24-hour after medication and they recovers in eight days in the eye irritation test employing rabbits and it is "slightly irritating", the dose is 0.05 mL which is smaller compared with current 0.1 mL of OECD TG 405 (SIDS (2006)). Although the recovery required 7 days or more, the symptom was thought to be mild and it was classified into Category 2B. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
4 | Respiratory sensitization | Classification not possible |
- |
- | - | Classification is not possible since there is no data. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
4 | Skin sensitization | Not classified |
- |
- | - | Although the result of the Maximization tests employing 30 guinea pig (OECD TG 406, GLP) was ambiguous, it was classified into "Not classified" since it was estimated as not sensitizing (SIDS (2006)) and was also not sensitizing (SIDS (2006)) in the Maximization test in 27 humans. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
5 | Germ cell mutagenicity | Not classified |
- |
- | - | Since it was negative (SIDS (2004)) in the body cell in vivo mutagenicity test (micronucleus test employing the bone marrow cell of the mouse (OECD TG 474, GLP)), it was classified into "Not classified". | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
6 | Carcinogenicity | Classification not possible |
- |
- | - | Since no evaluation by major international evaluation agencies is made and there is no data, classification is not possible. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
7 | Reproductive toxicity | Category 2 |
Warning |
H361 | P308+P313 P201 P202 P280 P405 P501 |
In the first generation reproductive toxicity study (OECD TG 415, GLP) via oral administration for 98 days using rats increase in the pre-mating time, decrease in fertilizing capacities, conception rates and the number of birth were observed and decrease of the body weight during the nursing period was observed among mother animals with 1,000mg/kg (recovering after the completion of the nursing period) (SIDS (2006)). At the same time, based on the description that decrease in the number of birth and body weight among baby animals during the nursing period was found (SIDS (2006)) as the fetal toxicity effect with 1,000mg/kg in the first generation reproductive toxicity study (OECD TG 415, GLP) via oral administration for 10 weeks using rats, it was classified in Category 2. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
8 | Specific target organ toxicity - Single exposure | Classification not possible |
- |
- | - | It has been described that although initial escape attempts were observed in the inhalation exposure test employing rats, there was no abnormality in the dissection during 8 hours exposure and after exposure (SIDS (2006)). Since the test concentration is unknown and there is no other data, classification is not possible. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
9 | Specific target organ toxicity - Repeated exposure | Not classified |
- |
- | - | As a result of testing by the dosage out of the range of the guidance value of Category 2 in 28-day oral administration test in rats (OECD TG 407,GLP), effects were found only on increase in liver, kidney, and lien weight (SIDS (2006)), therefore, it was classified into "Not classified". | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
10 | Aspiration hazard | Classification not possible |
- |
- | - | Classification is not possible because there is no data. In addition, the kinematic viscosity at 20degC is 86.03 mm2/s. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment Short term (Acute) | Category 1 |
Warning |
H400 | P273 P391 P501 |
It was classified into Category 1 from 48 hours EC50=0.13mg/L of the crustacea (Daphnia magna) (SIDS (2006)). | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
11 | Hazardous to the aquatic environment Long term (Chronic) | Category 1 |
Warning |
H410 | P273 P391 P501 |
Although acute toxicity was Category 1 and there were rapid degradability (the decomposition by BOD: >60% (SIDS (2006))), since there were bio-accumulation (LogKow = 8.23 (PHYSIPROP Database (2008))), it was classified into Category 1. | FY2008 | GHS Classification Guidance by the Japanese Government (Sep, 2008) |
12 | Hazardous to the ozone layer | - |
- |
- | - | - | - | - |
|