Item | Information |
---|---|
CAS RN | 55285-14-8 |
Chemical Name | 2,3-Dihydro-2,2-dimethyl-7-benzo[b]furyl N-(dibutylamino)thio-N-methylcarbamate |
Substance ID | m-nite-55285-14-8_v1 |
Download of Excel format | Excel file |
Item | Information |
---|---|
Guidance used for the classification (External link) | To Guidance List |
UN GHS document (External link) | To UN GHS document |
FAQ(GHS classification results by the Japanese Government) | To FAQ |
List of Information Sources (Excel file) | List of Information Sources |
List of Definitions/Abbreviations | Definitions/Abbreviations |
Sample Label by MHLW (External link) | MHLW Website (in Japanese Only) |
Sample SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
OECD/eChemPortal (External link) | To OECD/eChemPortal (External link) |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
1 | Explosives | Not classified (Not applicable) |
- |
- | - | Containing no chemical groups with explosive properties | FY2006 | GHS Classification Manual (10 Feb, 2006) |
2 | Flammable gases | Not classified (Not applicable) |
- |
- | - | Classified as "liquid" according to GHS definition | FY2006 | GHS Classification Manual (10 Feb, 2006) |
3 | Aerosols | Not classified (Not applicable) |
- |
- | - | Not aerosol products | FY2006 | GHS Classification Manual (10 Feb, 2006) |
4 | Oxidizing gases | Not classified (Not applicable) |
- |
- | - | Classified as "liquid" according to GHS definition | FY2006 | GHS Classification Manual (10 Feb, 2006) |
5 | Gases under pressure | Not classified (Not applicable) |
- |
- | - | Classified as "liquid" according to GHS definition | FY2006 | GHS Classification Manual (10 Feb, 2006) |
6 | Flammable liquids | Not classified |
- |
- | - | It was classified as "Not classified" from a flash point of 96 deg C (closed cup) (GESTIS (Accessed Jan. 2019)). | FY2018 | GHS Classification Guidance for the Japanese Government (FY2013 revised edition (Ver. 1.1)) |
7 | Flammable solids | Not classified (Not applicable) |
- |
- | - | Classified as "liquid" according to GHS definition | FY2006 | GHS Classification Manual (10 Feb, 2006) |
8 | Self-reactive substances and mixtures | Not classified (Not applicable) |
- |
- | - | Containing no chemical groups with explosive or self-reactive properties | FY2006 | GHS Classification Manual (10 Feb, 2006) |
9 | Pyrophoric liquids | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
10 | Pyrophoric solids | Not classified (Not applicable) |
- |
- | - | Classified as "liquid" according to GHS definition | FY2006 | GHS Classification Manual (10 Feb, 2006) |
11 | Self-heating substances and mixtures | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified (Not applicable) |
- |
- | - | Containing no metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
13 | Oxidizing liquids | Not classified (Not applicable) |
- |
- | - | Organic compounds containing oxygen (but not chlorine and fluorine), with the oxygen bound to carbon and hydrogen (but not to other elements) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
14 | Oxidizing solids | Not classified (Not applicable) |
- |
- | - | Classified as "liquid" according to GHS definition | FY2006 | GHS Classification Manual (10 Feb, 2006) |
15 | Organic peroxides | Not classified (Not applicable) |
- |
- | - | Organic compounds containing no "-O-O-" structure | FY2006 | GHS Classification Manual (10 Feb, 2006) |
16 | Corrosive to metals | Classification not possible |
- |
- | - | Classification not possible due to lack of data. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
17 | Desensitized explosives | - |
- |
- | - | - | - | - |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Category 3 |
Danger |
H301 | P301+P310 P264 P270 P321 P330 P405 P501 |
Based on the rat LD50 (oral route) value of 101mg/kg (Agricultural Chemical Registration Data (1981)). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Dermal) | - |
Warning |
- | - | Based on the rat LD50 (dermal route) value of 4,012mg/kg (Agricultural Chemical Registration Data (1981)). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Inhalation: Gases) | Not classified (Not applicable) |
- |
- | - | Due to the fact that the substance is a liquid according to the GHS definition and inhalation of its gas is not expected. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Inhalation: Vapours) | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Inhalation: Dusts and mists) | Category 2 |
Danger |
H330 | P304+P340 P403+P233 P260 P271 P284 P310 P320 P405 P501 |
Based on the rat LC50 (inhalation exposure) value of 0.15mg/L (4 hours) (Agricultural Chemical Registration Data (1981)). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
2 | Skin corrosion/irritation | Not classified |
- |
- | - | Based on the evidence of only mild irritation (the highest Draize score of 1.2), with effects fully clearing up within 6 days, observed in rabbit skin irritation tests (Agricultural Chemical Registration Data (1981)). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
3 | Serious eye damage/eye irritation | Category 2B |
Warning |
H320 | P305+P351+P338 P337+P313 P264 |
In the available rabbit eye irritation tests, irritation reactions were found only in the conjunctiva, and the effects fully cleared up by day 3 (Agricultural Chemical Registration Data (1981)). The substance is thus considered a mild eye irritant. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
4 | Respiratory sensitization | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
4 | Skin sensitization | Category 1 |
Warning |
H317 | P302+P352 P333+P313 P362+P364 P261 P272 P280 P321 P501 |
Based on the description in the report on guinea pig skin sensitization studies (Agricultural Chemical Registration Data (1981)): "The substance induced mild skin sensitization." | FY2006 | GHS Classification Manual (10 Feb, 2006) |
5 | Germ cell mutagenicity | Not classified |
- |
- | - | Based on negative data on in vitro reverse mutation tests (several indices) (Agricultural Chemical Registration Data (1981)), in vivo mouse somatic cell micronucleus tests (Agricultural Chemical Registration Data (1982)) and in vivo rat chromosome aberration tests (Agricultural Chemical Registration Data (1981)). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
6 | Carcinogenicity | Not classified |
- |
- | - | There was no treatment-related increase in tumor incidence observed in 2-year (rats) (Agricultural Chemical Registration Data (1982)) and 18-month (mice) (Agricultural Chemical Registration Data (1982)) carcinogenicity studies. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
7 | Reproductive toxicity | Not classified |
- |
- | - | Based on no evidence of adverse effects on parental reproduction and offspring development in rat 3-generation reproductive toxicity studies (Agricultural Chemical Registration Data (1982)) and rat/rabbit teratogenicity studies (Agricultural Chemical Registration Data (1981)). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
8 | Specific target organ toxicity - Single exposure | Category 1 (nervous system, gastrointestinal tract) |
Danger |
H370 | P308+P311 P260 P264 P270 P321 P405 P501 |
In rat single dose toxicity studies, clinical signs and symptoms including reduced locomotor activity, tremors, back muscle fasciculation, salivation, lacrimation, splinter hemorrhage of the fundus were reported (Agricultural Chemical Registration Data (1981)). The effects on experimental animals were observed at dosing levels within the guidance value ranges for Category 1. |
FY2006 | GHS Classification Manual (10 Feb, 2006) |
9 | Specific target organ toxicity - Repeated exposure | Category 2 (blood system) |
Warning |
H373 | P260 P314 P501 |
In the available rat repeated dose toxicity studies, decreased hematocrit levels, low lymphocyte levels and high segmented cell levels were detected (Agricultural Chemical Registration Data (1981)). These effects were observed at dosing levels within the guidance value ranges for Category 2. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
10 | Aspiration hazard | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment Short term (Acute) | Category 1 |
Warning |
H400 | P273 P391 P501 |
It was classified into Category 1 from 48 hours EC50=0.00103mg/L of the crustacea (Daphnia magna) (Agricultural Chemical Registration Data, 2004). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
11 | Hazardous to the aquatic environment Long term (Chronic) | Category 1 |
Warning |
H410 | P273 P391 P501 |
Since acute toxicity was Category 1 and there was no rapidly degrading (BIOWIN), and since there wasbio-accumulation (log Kow=5.57 (PHYSPROP Database, 2005)), it was classified into Category 1. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
12 | Hazardous to the ozone layer | - |
- |
- | - | - | - | - |
|