NITE - Chemical Management Field

Latest GHS Classification Results by the Japanese Government (edited by NITE)

GENERAL INFORMATION

Item	Information
CAS RN	68476-31-3
Chemical Name	Fuel oil, No 4; Gasoil - unspecified
Substance ID	m-nite-68476-31-3_v1
Download of Excel format	Excel file

REFERENCE INFORMATION

Item	Information
Guidance used for the classification (External link)	To Guidance List
UN GHS document (External link)	To UN GHS document
FAQ（GHS classification results by the Japanese Government）	To FAQ
List of Information Sources (Excel file)	List of Information Sources
List of Definitions/Abbreviations	Definitions/Abbreviations
Sample Label by MHLW (External link)	MHLW Website (in Japanese Only)
Sample SDS by MHLW (External link)	MHLW Website (in Japanese Only)
OECD/eChemPortal (External link)	To OECD/eChemPortal (External link)

PHYSICAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
1	Explosives	Not classified (Not applicable)	- -	-	-	Due to dissociation of nitrogen and oxygen from hydrocarbon through the formation of ammonia and water, the saturation of unsaturated bonds and the deposition and separation of its metal components by the catalysts during the hydrorefining process, the substance does not contain chemical groups associated with explosive properties.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
2	Flammable gases	Not classified (Not applicable)	- -	-	-	Liquid (GHS definition)	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
3	Aerosols	Not classified (Not applicable)	- -	-	-	Not aerosol products.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
4	Oxidizing gases	Not classified (Not applicable)	- -	-	-	Liquid (GHS definition)	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
5	Gases under pressure	Not classified (Not applicable)	- -	-	-	Liquid (GHS definition)	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
6	Flammable liquids	Category 3	Warning	H226	P303+P361+P353 P370+P378 P403+P235 P210 P233 P240 P241 P242 P243 P280 P501	Its flash point is > 54degC (EHC, ATSDR) or >= 55degC (CONCAWE, ATSDR), which is in the range between 23 and 60 degC.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
7	Flammable solids	Not classified (Not applicable)	- -	-	-	Liquid (GHS definition)	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
8	Self-reactive substances and mixtures	Not classified (Not applicable)	- -	-	-	Due to dissociation of nitrogen and oxygen from hydrocarbon through the formation of ammonia and water, the saturation of unsaturated bonds and the deposition and separation of its metal components by the catalysts during the hydrorefining process, the substance does not contain chemical groups associated with explosive or self-reactive properties.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
9	Pyrophoric liquids	Not classified	- -	-	-	Its flash point is 254-285degC (ACGIH) or 263degC (EHC, ATSDR).	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
10	Pyrophoric solids	Not classified (Not applicable)	- -	-	-	Liquid (GHS definition)	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
11	Self-heating substances and mixtures	Classification not possible	- -	-	-	Test methods applicable to liquid substances are not available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
12	Substances and mixtures which, in contact with water, emit flammable gases	Not classified (Not applicable)	- -	-	-	Due to deposition and separation of its metal components by the catalysts during the hydrorefining process, the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
13	Oxidizing liquids	Not classified (Not applicable)	- -	-	-	Due to dissociation of oxygen from hydrocarbon through water formation, and the deposition and separation of its metal components by the catalysts during the hydrorefining process, the substance does not contain oxygen or halogen.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
14	Oxidizing solids	Not classified (Not applicable)	- -	-	-	Liquid (GHS definition)	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
15	Organic peroxides	Not classified (Not applicable)	- -	-	-	Due to dissociation of oxygen from hydrocarbon through water formation during the hydrorefining process, the substance is considered as an organic compound containing no bivalent -O-O- structure.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
16	Corrosive to metals	Classification not possible	- -	-	-	No data available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
17	Desensitized explosives	-	- -	-	-	-	-	-

HEALTH HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
1	Acute toxicity (Oral)	Not classified	- -	-	-	Its rat LD50 values are 7500 mg/kg (EHC) and 74000 mg/kg (IUCLID). Its mouse LD50 value is > 16000 mg/kg (EHC).	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
1	Acute toxicity (Dermal)	Not classified	- -	-	-	Its mouse LD50 values are > 16000 mg/kg (EHC) and > 40000 mg/kg (EHC). Its rabbit LD50 value is > 5000 mg/kg (EHC).	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
1	Acute toxicity (Inhalation: Gases)	Classification not possible	- -	-	-	LD50 > NOAEL. 4-hour conversion of NOAEL (6hrs10 days) = 401.5sqrt(60)/sqrt(4) = approx. 1500 ppmV. The substance falls under between Category 3 and "Not classified" category in the JIS classification.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
1	Acute toxicity (Inhalation: Vapours)	Classification not possible	- -	-	-	No data available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
1	Acute toxicity (Inhalation: Dusts and mists)	Classification not possible	- -	-	-	LD50 > NOAEL. 4-hour conversion of NOAEL (6hrs) (ATSDR) = 2.7 mg/L*6/4 = 4.05. The substance falls under between Category 4 and "Not classified" category in the JIS classification.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
2	Skin corrosion/irritation	Classification not possible	- -	-	-	While GLP-compliant rabbit tests found that the substance is severely irritating (IUCLID) (equivalent to Category 1 or 2), rat or other rabbit tests found that it induces no response (EHC, ACGIH) (equivalent to "Not classified" category).	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
3	Serious eye damage/eye irritation	Not classified	- -	-	-	GLP-compliant rabbit tests resulted in a Draize score of 0.0 (not irritating) (IUCLID)	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
4	Respiratory sensitization	Classification not possible	- -	-	-	There is a description that the substance is not sensitizing (EHC); however, no data are available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
4	Skin sensitization	Classification not possible	- -	-	-	There is a description that the substance is not sensitizing (EHC); however, no data are available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
5	Germ cell mutagenicity	Category 2	Warning	H341	P308+P313 P201 P202 P280 P405 P501	In vivo mutagenicity tests using germ cells (rodent dominant lethal tests) yielded negative results (ATSDR), while in vivo mutagenicity tests using somatic cells (mammalian bone marrow chromosome aberration tests) found positive results (ATSDR). In vivo genotoxicity tests using germ cells are not available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
6	Carcinogenicity	Category 2	Warning	H351	P308+P313 P201 P202 P280 P405 P501	In dermally administered mice, squamous-cell, papillomas and carcinomas (EHC), or hepatocellular adenoma or carcinoma (ATSDR) were observed. The IARC lists the substance as Group 2B, and describes that marine diesel fuel is possible carcinogenic to humans.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
7	Reproductive toxicity	Classification not possible	- -	-	-	13-week inhalation (mist) tests found no effects of the substance on weight and tissues of reproductive organs; however, there was no information on the developmental toxicity in offspring (ACGIH). In the tests in which test animals underwent inhalation exposure (mist) between day 6 and 15 of pregnancy, the substance is reported to have only general toxicity to parental animals, and no developmental toxicity to offspring or no effects on sex ratio; however, no information available of its toxicity on sexual functions or fertility of animals that experienced exposure before becoming pregnant (ACGIH).	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
8	Specific target organ toxicity - Single exposure	Category 1 (circulatory organ, respiratory organs)	Danger	H370	P308+P311 P260 P264 P270 P321 P405 P501	Inhalation exposure (vapour) was associated with development of bronchitis and ventricular tachycardia (ACGIH). Oral route exposure was associated with toxic lung diseases (ACGIH).	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
9	Specific target organ toxicity - Repeated exposure	Classification not possible	- -	-	-	In dermal administration, a wide range of NOAEL has been reported: 2000 (ATSDR), 1000 (EHC), and < 250 mg/kg/day (ATSDR) for the skin; and 4000 (ATSDR), < 228 (ACGIH), and < 250 mg/kg/day (ATSDR) for the kidney. In inhalation administration (mist), the substance was categorized into "Not classified" for all health hazards except for the kidney, nervous system, and systemic hazards (EHC, ACGIH, ATSDR).	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
10	Aspiration hazard	Category 1	Danger	H304	P301+P310 P331 P405 P501	There is documentation on several cases of serious toxic lung diseases in humans (ACGIH). Its kinematic viscosity is 45-125SUS (EU-Annex 1) (conversion value: 8.6-27.0 mm2/s at 37.7degC).	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
11	Hazardous to the aquatic environment Short term (Acute)	Classification not possible	- -	-	-	No data available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
11	Hazardous to the aquatic environment Long term (Chronic)	Classification not possible	- -	-	-	No data available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
12	Hazardous to the ozone layer	-	- -	-	-	-	-	-

NOTE:

GHS Classification Result by the Japanese Government is intended to provide a reference for preparing a GHS label or SDS for users. To include the same classification result in a label or SDS for Japan is NOT mandatory.
Users can cite or copy this classification result when preparing a GHS label or SDS. Please be aware, however, that the responsibility for a label or SDS prepared by citing or copying this classification result lies with users.
This GHS classification was conducted based on the information sources and the guidance for classification and judgement which are described in the GHS Classification Guidance for the Japanese Government etc. Using other literature, test results etc. as evidence and including different content from this classification result in a label or SDS are allowed.
Hazard statement and precautionary statement will show by hovering the mouse cursor over a code in the column of "Hazard statement" and "Precautionary statement," respectively. In the excel file, both the codes and statements are provided.
A blank or "-" in the column of "Classification" denotes that a classification for the hazard class was not conducted in the year.
An asterisk “*” in the column of “Classification” denotes that “Not classified (or No applicable)” and/or “Classification not possible” is applicable. Details are described in the column of “Rationale for the classification”. If no English translation is available for “Rationale for the classification,” please refer to the Japanese version of the results.

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