Item | Information |
---|---|
CAS RN | 75-43-4 |
Chemical Name | dichlorofluoromethane |
Substance ID | m-nite-75-43-4_v1 |
Download of Excel format | Excel file |
Item | Information |
---|---|
Guidance used for the classification (External link) | To Guidance List |
UN GHS document (External link) | To UN GHS document |
FAQ(GHS classification results by the Japanese Government) | To FAQ |
List of Information Sources (Excel file) | List of Information Sources |
List of Definitions/Abbreviations | Definitions/Abbreviations |
Sample Label by MHLW (External link) | MHLW Website (in Japanese Only) |
Sample SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
OECD/eChemPortal (External link) | To OECD/eChemPortal (External link) |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
1 | Explosives | Not classified (Not applicable) |
- |
- | - | Gas (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
2 | Flammable gases | Not classified |
- |
- | - | UNRTDG Class: 2.1. Non-combustible or hardly flammable gas (Hommel, 1991) and non-combustible (ICSC(J), 19XX) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
3 | Aerosols | Not classified (Not applicable) |
- |
- | - | Not aerosol products | FY2006 | GHS Classification Manual (10 Feb, 2006) |
4 | Oxidizing gases | Not classified |
- |
- | - | UNRTDG Class: 2.2 | FY2006 | GHS Classification Manual (10 Feb, 2006) |
5 | Gases under pressure | Liquefied gas |
Warning |
H280 | P410+P403 | Liquefied gas because of the critical temp: >65degC. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
6 | Flammable liquids | Not classified (Not applicable) |
- |
- | - | Gas (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
7 | Flammable solids | Not classified (Not applicable) |
- |
- | - | Gas (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
8 | Self-reactive substances and mixtures | Not classified (Not applicable) |
- |
- | - | Gas (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
9 | Pyrophoric liquids | Not classified (Not applicable) |
- |
- | - | Gas (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
10 | Pyrophoric solids | Not classified (Not applicable) |
- |
- | - | Gas (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
11 | Self-heating substances and mixtures | Not classified (Not applicable) |
- |
- | - | Gas (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified (Not applicable) |
- |
- | - | Gas (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
13 | Oxidizing liquids | Not classified (Not applicable) |
- |
- | - | Solid (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
14 | Oxidizing solids | Not classified (Not applicable) |
- |
- | - | Liquid (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
15 | Organic peroxides | Not classified (Not applicable) |
- |
- | - | Gas (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
16 | Corrosive to metals | Classification not possible |
- |
- | - | Test methods are not available. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
17 | Desensitized explosives | - |
- |
- | - | - | - | - |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Dermal) | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Inhalation: Gases) | Not classified |
- |
- | - | Based on rat inhalation LC50 = 49900ppm (4hr) (ACGIH (2001)), it was considered as the outside of Category. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Inhalation: Vapours) | Not classified (Not applicable) |
- |
- | - | Gas (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Inhalation: Dusts and mists) | Not classified (Not applicable) |
- |
- | - | Gas (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
2 | Skin corrosion/irritation | Category 3 |
Warning |
- | - | Based on a report that mild irritation arises with 25% or more of concentration to intact skin in the examination on guinea pigs report (EHC 126 (1991)), it was classified as Category 3. [Notes] There is also a report that it was a frostbite caused by coolant effect (Hommmel (1991)). |
FY2006 | GHS Classification Manual (10 Feb, 2006) |
3 | Serious eye damage/eye irritation | Category 2B |
Warning |
H320 | P305+P351+P338 P337+P313 P264 |
Since reversible Milder irritant effects (EHC 126 (1991)) were reported in solution 15% by the examination of the rabbit, it was set as Category 2B. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
4 | Respiratory sensitization | Classification not possible |
- |
- | - | No data | FY2006 | GHS Classification Manual (10 Feb, 2006) |
4 | Skin sensitization | Not classified |
- |
- | - | Classified as out of category based on the report that finds no sensitization in the experiment by the Maximization method using guinea pigs (CERI Hazard Data (2000)), and the description that guinea pig tests shows no sensitization (EHC 126 (1991), ECETOC JACC16 (1990), PATTY(5th, 2001) vol.5). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
5 | Germ cell mutagenicity | Classification not possible |
- |
- | - | It was decided that the substance could not be classified because there are no data from in vivo tests, and there are no positive results from the in vitro mutagenicity tests (EHC 126 (1991), DFGOT vol.5 (1993)). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
6 | Carcinogenicity | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
7 | Reproductive toxicity | Category 2 |
Warning |
H361 | P308+P313 P201 P202 P280 P405 P501 |
It is reported that loss of implantation in the amount of administration causing the reduced weight of parent animals in the test using rat (EHC 126 (1991), ACGIH (2001)). So it was considered as in the Category 2. , | FY2006 | GHS Classification Manual (10 Feb, 2006) |
8 | Specific target organ toxicity - Single exposure | Category 3 (Narcotic effects) |
Warning |
H336 | P304+P340 P403+P233 P261 P271 P312 P405 P501 |
Based on the report of anesthetic actions in rat and guinea pig, it was classified into Category 3 (anesthetic actions). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
9 | Specific target organ toxicity - Repeated exposure | Category 1 (liver) |
Danger |
H372 | P260 P264 P270 P314 P501 |
Since Cirrhosis is observed histopathologically in rat at 50 ppm (EHC 126 (1991)) and despite out of guidance value, the necrosis of liver was also observed at 10000 ppm (EHC 126 (1991), ACGIH (2001)), it was classified into Category 1 (liver). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
10 | Aspiration hazard | Not classified (Not applicable) |
- |
- | - | Gas (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment Short term (Acute) | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
11 | Hazardous to the aquatic environment Long term (Chronic) | Classification not possible |
- |
- | - | No data available. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
12 | Hazardous to the ozone layer | - |
- |
- | - | - | - | - |
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