NITE - Chemical Management Field

Latest GHS Classification Results by the Japanese Government (edited by NITE)

GENERAL INFORMATION

Item	Information
CAS RN	8012-95-1,8002-05-9,64741-88-4,64741-97-5,72623-86-0,72623-87-1
Chemical Name	Distillates (petroleum), solvent-refined heavy paraffinic; Distillates (petroleum), solvent-refined light naphthenic; Lubricating oils (petroleum), C15-30, hydrotreated neutral oil-based; Lubricating oils (petroleum), C20-50, hydrotreated neutral oil-based; Petroleum; Paraffin oils
Substance ID	m-nite-8012-95-1_v1
Download of Excel format	Excel file

REFERENCE INFORMATION

Item	Information
Guidance used for the classification (External link)	To Guidance List
UN GHS document (External link)	To UN GHS document
FAQ（GHS classification results by the Japanese Government）	To FAQ
List of Information Sources (Excel file)	List of Information Sources
List of Definitions/Abbreviations	Definitions/Abbreviations
Sample Label by MHLW (External link)
Sample SDS by MHLW (External link)
OECD/eChemPortal (External link)	To OECD/eChemPortal (External link)

PHYSICAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
1	Explosives	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
2	Flammable gases	Not classified (Not applicable)	- -	-	-	Liquid (room temperature)	FY2006	GHS Classification Manual （10 Feb, 2006）
3	Aerosols	Not classified (Not applicable)	- -	-	-	Not aerosol products	FY2006	GHS Classification Manual （10 Feb, 2006）
4	Oxidizing gases	Not classified (Not applicable)	- -	-	-	Liquid (room temperature)	FY2006	GHS Classification Manual （10 Feb, 2006）
5	Gases under pressure	Not classified (Not applicable)	- -	-	-	Liquid (room temperature)	FY2006	GHS Classification Manual （10 Feb, 2006）
6	Flammable liquids	Not classified	- -	-	-	Not classified because of its flash point: 149-232degC (NFPA, 13th, 2002)	FY2006	GHS Classification Manual （10 Feb, 2006）
7	Flammable solids	Not classified (Not applicable)	- -	-	-	Liquid (room temperature)	FY2006	GHS Classification Manual （10 Feb, 2006）
8	Self-reactive substances and mixtures	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
9	Pyrophoric liquids	Not classified	- -	-	-	The ignition points is 260 - 371 degC (NFPA (13th, 2002)), and exceeds 70 degC.	FY2006	GHS Classification Manual （10 Feb, 2006）
10	Pyrophoric solids	Not classified (Not applicable)	- -	-	-	Liquid (room temperature)	FY2006	GHS Classification Manual （10 Feb, 2006）
11	Self-heating substances and mixtures	Classification not possible	- -	-	-	Test methods applicable to liquid substances are not available	FY2006	GHS Classification Manual （10 Feb, 2006）
12	Substances and mixtures which, in contact with water, emit flammable gases	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
13	Oxidizing liquids	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
14	Oxidizing solids	Not classified (Not applicable)	- -	-	-	Liquid (room temperature)	FY2006	GHS Classification Manual （10 Feb, 2006）
15	Organic peroxides	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
16	Corrosive to metals	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
17	Desensitized explosives	-	- -	-	-	-	-	-

HEALTH HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
1	Acute toxicity (Oral)	Not classified	- -	-	-	SPECIES: Rat ENDPOINT: LD50 VALUE: > 5000 mg/kg REFERENCE SOURCE: IUCLID (2000)	FY2006	GHS Classification Manual （10 Feb, 2006）
1	Acute toxicity (Dermal)	Not classified	- -	-	-	Based on rat LD50 >5000mg/kg (IUCLID (2000)), it was set as the outside of Category.	FY2006	GHS Classification Manual （10 Feb, 2006）
1	Acute toxicity (Inhalation: Gases)	Not classified (Not applicable)	- -	-	-	Liquid (room temperature)	FY2006	GHS Classification Manual （10 Feb, 2006）
1	Acute toxicity (Inhalation: Vapours)	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
1	Acute toxicity (Inhalation: Dusts and mists)	Category 4	Warning	H332	P304+P340 P261 P271 P312	Category 4 because of "SPECIES: Rat; ENDPOINT: LC50 = 2.18 mg/L." (IUCLID, 2000)	FY2006	GHS Classification Manual （10 Feb, 2006）
2	Skin corrosion/irritation	Category 3	- Warning	-	-	It was classified as Category 3 based on several reports which observed mild irritation in rabbit tests (IUCLID (2000)).	FY2006	GHS Classification Manual （10 Feb, 2006）
3	Serious eye damage/eye irritation	Category 2B	- Warning	H320	P305+P351+P338 P337+P313 P264	By the test using a rabbit, there was a report (IUCLID (2000)) described to be mild irritation. So it was set as Category 2B.	FY2006	GHS Classification Manual （10 Feb, 2006）
4	Respiratory sensitization	Classification not possible	- -	-	-	No data	FY2006	GHS Classification Manual （10 Feb, 2006）
4	Skin sensitization	Not classified	- -	-	-	In multiple tests(including the maximization test) based on OECD Guideline 406 using the guinea pigs, a result that none of them had the sensitization was obtained (IUCLID (2000)), and therefore it was put outside of the Category.	FY2006	GHS Classification Manual （10 Feb, 2006）
5	Germ cell mutagenicity	Category 2	Warning	H341	P308+P313 P201 P202 P280 P405 P501	Based on the increase in the abnormal cells in the cytogenetic study [chromosomal aberration test] (somatic cell in vivo mutagenicity test) using the rat (IUCLID (2000)), and based on the fact that increase was observed in frequency of the chromosomal aberration in the peripheral blood lymphocyte of the human who received occupational exposure (IARC suppl.7 (1987)), and on the fact that there being no information about the productive cell in vivo genotoxicity study. So we classified it as Category 2.	FY2006	GHS Classification Manual （10 Feb, 2006）
6	Carcinogenicity	Category 1A	Danger	H350	P308+P313 P201 P202 P280 P405 P501	Un-refined or slight processed oil is classified into group 1, and highly refined oil is into group 3 (IARC (1987)), and the proposal of ACGIH (2006) can also be said to be the almost same category. It is classified into the 1st group according to Occupational Health Society (1977) as un-refined and a half-refined article. As mentioned above, according to the classification of IARC which the classification has decided, highly refined oil is set to outside of category and unrefined oils or low grade treated oil to Category 1A.	FY2006	GHS Classification Manual （10 Feb, 2006）
7	Reproductive toxicity	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
8	Specific target organ toxicity - Single exposure	Category 2 (lung)	Warning	H371	P308+P311 P260 P264 P270 P405 P501	There is the statement that there is the grossly, histopathological acute changes (details unknown) in dependance to dose (1.51 - 5.05mg/L) in the rat test of inhalation exposure (IUCLID (2000)), it is classified into Category 3 (lung).	FY2006	GHS Classification Manual （10 Feb, 2006）
9	Specific target organ toxicity - Repeated exposure	Category 1 (lung, skin)	Danger	H372	P260 P264 P270 P314 P501	It was classified to as Category 1 (lungs, skin) since that pulmonary fibrosis, lipid pneumonias and lipogranuloma of lungs are reported in humans who received exposure of the mineral oils or the mist over many years (ACGIH (2001) and IARC 33 (1984),EHC 20 (1982)), and generation of the serious folliculitis is reported in the epidemiological study by occupational exposure to cutting oil (IARC 33 (1984)).	FY2006	GHS Classification Manual （10 Feb, 2006）
10	Aspiration hazard	Category 1	Danger	H304	P301+P310 P331 P405 P501	It was classified into Category 1 based on the reports that ingestion of mineral oil causes the aspiration into the lungs, and as a result it occures the pneumonie huileuses or chemical pneumonia in the human (EHC 20 (1982), IARC 33 (1984), ICSC (2001), ACGIH (2001)).	FY2006	GHS Classification Manual （10 Feb, 2006）

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
11	Hazardous to the aquatic environment Short term (Acute)	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
11	Hazardous to the aquatic environment Long term (Chronic)	Classification not possible	- -	-	-	No data available.	FY2006	GHS Classification Manual （10 Feb, 2006）
12	Hazardous to the ozone layer	-	- -	-	-	-	-	-

NOTE:

GHS Classification Result by the Japanese Government is intended to provide a reference for preparing a GHS label or SDS for users. To include the same classification result in a label or SDS for Japan is NOT mandatory.
Users can cite or copy this classification result when preparing a GHS label or SDS. Please be aware, however, that the responsibility for a label or SDS prepared by citing or copying this classification result lies with users.
This GHS classification was conducted based on the information sources and the guidance for classification and judgement which are described in the GHS Classification Guidance for the Japanese Government etc. Using other literature, test results etc. as evidence and including different content from this classification result in a label or SDS are allowed.
Hazard statement and precautionary statement will show by hovering the mouse cursor over a code in the column of "Hazard statement" and "Precautionary statement," respectively. In the excel file, both the codes and statements are provided.
A blank or "-" in the column of "Classification" denotes that a classification for the hazard class was not conducted in the year.
An asterisk “*” in the column of “Classification” denotes that “Not classified (or No applicable)” and/or “Classification not possible” is applicable. Details are described in the column of “Rationale for the classification”. If no English translation is available for “Rationale for the classification,” please refer to the Japanese version of the results.

To GHS Information