NITE - Chemical Management Field

Latest GHS Classification Results by the Japanese Government (edited by NITE)

GENERAL INFORMATION

Item	Information
CAS RN	83130-01-2
Chemical Name	alanycarb
Substance ID	m-nite-83130-01-2_v1
Download of Excel format	Excel file

REFERENCE INFORMATION

Item	Information
Guidance used for the classification (External link)	To Guidance List
UN GHS document (External link)	To UN GHS document
FAQ（GHS classification results by the Japanese Government）	To FAQ
List of Information Sources (Excel file)	List of Information Sources
List of Definitions/Abbreviations	Definitions/Abbreviations
Sample Label by MHLW (External link)	MHLW Website (in Japanese Only)
Sample SDS by MHLW (External link)	MHLW Website (in Japanese Only)
OECD/eChemPortal (External link)	To OECD/eChemPortal (External link)

PHYSICAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
1	Explosives	Classification not possible	- -	-	-	Classification not possible due to lack of data, though the substance contains N-O bonds as chemical groups with explosive properties present and has the oxygen balance calculated at -186.2, higher than -200 of the criteria.	FY2006	GHS Classification Manual （10 Feb, 2006）
2	Flammable gases	Not classified (Not applicable)	- -	-	-	Solid (GHS definition)	FY2006	GHS Classification Manual （10 Feb, 2006）
3	Aerosols	Not classified (Not applicable)	- -	-	-	Not aerosol products	FY2006	GHS Classification Manual （10 Feb, 2006）
4	Oxidizing gases	Not classified (Not applicable)	- -	-	-	Solid (GHS definition)	FY2006	GHS Classification Manual （10 Feb, 2006）
5	Gases under pressure	Not classified (Not applicable)	- -	-	-	Solid (GHS definition)	FY2006	GHS Classification Manual （10 Feb, 2006）
6	Flammable liquids	Not classified (Not applicable)	- -	-	-	Solid (GHS definition)	FY2006	GHS Classification Manual （10 Feb, 2006）
7	Flammable solids	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
8	Self-reactive substances and mixtures	Classification not possible	- -	-	-	Classification not possible due to lack of data, though the substance contains N-O bonds as chemical groups with explosive or self-reactive properties present	FY2006	GHS Classification Manual （10 Feb, 2006）
9	Pyrophoric liquids	Not classified (Not applicable)	- -	-	-	Solid (GHS definition)	FY2006	GHS Classification Manual （10 Feb, 2006）
10	Pyrophoric solids	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
11	Self-heating substances and mixtures	Classification not possible	- -	-	-	The test suitable for the solid with a melting point of 140 degC or less has not been established. (melting points: 46.6 - 47 degC)	FY2006	GHS Classification Manual （10 Feb, 2006）
12	Substances and mixtures which, in contact with water, emit flammable gases	Not classified (Not applicable)	- -	-	-	The chemical structure of the substance does not contain metals or metaloids(B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).	FY2006	GHS Classification Manual （10 Feb, 2006）
13	Oxidizing liquids	Not classified (Not applicable)	- -	-	-	Solid (GHS definition)	FY2006	GHS Classification Manual （10 Feb, 2006）
14	Oxidizing solids	Classification not possible	- -	-	-	Classification not possible due to lack of data, though containing oxygen bonded to nitrogen.	FY2006	GHS Classification Manual （10 Feb, 2006）
15	Organic peroxides	Not classified (Not applicable)	- -	-	-	Organic compounds containing no -0-0- structure	FY2006	GHS Classification Manual （10 Feb, 2006）
16	Corrosive to metals	Classification not possible	- -	-	-	No data available (Melting point: 46.6-47degC)	FY2006	GHS Classification Manual （10 Feb, 2006）
17	Desensitized explosives	-	- -	-	-	-	-	-

HEALTH HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
1	Acute toxicity (Oral)	Category 4	Warning	H302	P301+P312 P264 P270 P330 P501	We compared the LD50 values for male and female rats in Oral Toxicity tests, and based on the lower value of these groups, LD50=397mg/kg (Agricultural Chemical Registration Data), we classified the substance as Category 4.	FY2006	GHS Classification Manual （10 Feb, 2006）
1	Acute toxicity (Dermal)	Not classified	- -	-	-	Based on rat LD50 >2000mg/kg of the dermal toxicity tests (no death case) (Agricultural Chemical Registration Data), it was set as the outside of Category.	FY2006	GHS Classification Manual （10 Feb, 2006）
1	Acute toxicity (Inhalation: Gases)	Not classified (Not applicable)	- -	-	-	Solid (GHS definition)	FY2006	GHS Classification Manual （10 Feb, 2006）
1	Acute toxicity (Inhalation: Vapours)	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
1	Acute toxicity (Inhalation: Dusts and mists)	Classification not possible	- -	-	-	Death was not seen in 0.205mg/L by the inhalation toxicity studies using rats. But LC50 value was not acquired (Agricultural Chemical Registration Data). Therefore, it cannot be classified.	FY2006	GHS Classification Manual （10 Feb, 2006）
2	Skin corrosion/irritation	Not classified	- -	-	-	It was carried out the outside of category based on the primary skin irritation test using a rabbit, in which the irritation was admitted in neither of the animals, and the primary irritation index (P. I.I.) has also been 0 (Agricultural Chemical Registration Data) .	FY2006	GHS Classification Manual （10 Feb, 2006）
3	Serious eye damage/eye irritation	Not classified	- -	-	-	In the eye primary irritation study using the rabbit, it made out of Category based on the result that severe damage/ eye irritation are not acquired during observation time (Agricultural Chemical Registration Data).	FY2006	GHS Classification Manual （10 Feb, 2006）
4	Respiratory sensitization	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
4	Skin sensitization	Not classified	- -	-	-	Based on the statement (Agricultural Chemical Registration Data) with negativity by the skin sensitization study using a guinea pig, it carried out the outside of Category.	FY2006	GHS Classification Manual （10 Feb, 2006）
5	Germ cell mutagenicity	Not classified	- -	-	-	There is no data of human administration cost epidemiology, an administration cost mutagenicity test, and productive cell in vivo mutagenicity test. And the statement (Agricultural Chemical Registration Data) with negativity by two somatic cell in vivo mutagenicity tests (the in vivo chromosomal aberration test using rat myeloid cells, and the micronucleus test which uses mouse red corpuscles). So it carried out the outside of Category.	FY2006	GHS Classification Manual （10 Feb, 2006）
6	Carcinogenicity	Not classified	- -	-	-	Since in carcinogenicity test using mouse treatment-related increased tumor was not observed (Agricultural Chemical Registration Data), it was out of Category.	FY2006	GHS Classification Manual （10 Feb, 2006）
7	Reproductive toxicity	Not classified	- -	-	-	In oral administration study using rats and rabbits, mischief of reproductive performance and freproductive potential against parental animals were not seen, and that fetustoxic and the teratogenicity to child animals are not acknowledged (Agricultural-chemicals applications for registration). So it carried out the outside of Category.	FY2006	GHS Classification Manual （10 Feb, 2006）
8	Specific target organ toxicity - Single exposure	Category 1 (systemic, nervous system)	Danger	H370	P308+P311 P260 P264 P270 P321 P405 P501	It was considered as Category 1 (systemicity, nervous system) based on the description (Agricultural Chemical Registration Data) that in oral administration and inhalation (dust) administration of a rat, at the dosage (200mg/kg, 0.2mg/L) within the range of guidance value in Category 1, diminished spontaneous activity, red effluents from eyes and nasal, ataxie, behavior inhibiting, weakness, salivation, tremor, the round back, and eyeballs protrusion etc., were observed.	FY2006	GHS Classification Manual （10 Feb, 2006）
9	Specific target organ toxicity - Repeated exposure	Category 2 (systemic, nervous system)	Warning	H373	P260 P314 P501	It was classified into Category 2 (systemic, nervous system) based on the description that in the examination of a rat, by the dosage (11.4 mg/kg and 38.9 mg/kg) within the range of guidance value of Category 2 , the influence on decreased weight gain, and hematologic values, and decrease of erythrocyte cholinesterase activity were observed (Agricultural Chemical Registration Data).	FY2006	GHS Classification Manual （10 Feb, 2006）
10	Aspiration hazard	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
11	Hazardous to the aquatic environment Short term (Acute)	Category 1	Warning	H400	P273 P391 P501	It was classified into Category 1 from 48-hour EC50=0.05mg/L of Crustacea (Daphnia magna) (Agricultural Chemical Registration Data, 1992).	FY2006	GHS Classification Manual （10 Feb, 2006）
11	Hazardous to the aquatic environment Long term (Chronic)	Category 1	Warning	H410	P273 P391 P501	Classified into Category 1, since acute toxicity was Category 1, supposed not rapidly degrading (BIOWIN), though supposed less bioaccumulative (log Kow=3.43(PHYSPROP Database, 2005)).	FY2006	GHS Classification Manual （10 Feb, 2006）
12	Hazardous to the ozone layer	-	- -	-	-	-	-	-

NOTE:

GHS Classification Result by the Japanese Government is intended to provide a reference for preparing a GHS label or SDS for users. To include the same classification result in a label or SDS for Japan is NOT mandatory.
Users can cite or copy this classification result when preparing a GHS label or SDS. Please be aware, however, that the responsibility for a label or SDS prepared by citing or copying this classification result lies with users.
This GHS classification was conducted based on the information sources and the guidance for classification and judgement which are described in the GHS Classification Guidance for the Japanese Government etc. Using other literature, test results etc. as evidence and including different content from this classification result in a label or SDS are allowed.
Hazard statement and precautionary statement will show by hovering the mouse cursor over a code in the column of "Hazard statement" and "Precautionary statement," respectively. In the excel file, both the codes and statements are provided.
A blank or "-" in the column of "Classification" denotes that a classification for the hazard class was not conducted in the year.
An asterisk “*” in the column of “Classification” denotes that “Not classified (or No applicable)” and/or “Classification not possible” is applicable. Details are described in the column of “Rationale for the classification”. If no English translation is available for “Rationale for the classification,” please refer to the Japanese version of the results.

To GHS Information