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General Information
- General Information
  - General Information Data Description
    - CHRIP_ID C004-661-64A CAS RN 106-47-8
      
      Chemical Substance Name 4-Chloroaniline
      
      Molecular Formula C6H6ClN
      
      Molecular Weight 128
      
      SMILES ClC1=CC=C(C=C1)N
      
      Structure
- Synonym
  - Synonym Data Description
    - Synonym Benzenamine, 4-chloro-
      
      Chloroaminobenzene, p-
      
      Chloroaniline, p-
      
      p-Chloroaniline
      
      para-Chloroaniline
- Nikkaji
  - Information of Japan Chemical Substance Dictionary (Nikkaji) Data Description
    - Nikkaji Number
      J4.034G
      Detail to J-GLOBAL

Laws and Regulations in Japan

Act on the Evaluation of Chemical Substances and Regulation of Their Manufacture, etc. (Chemical Substances Control Law ; CSCL)

Japan CSCL: Existing Chemical Substances Data Description Definition of the terms of Section 6 [PDF] Definition of the terms of Section 7 [PDF] Import Clearance Procedures[PDF] Notification of the Manufacturing Amount, etc[PDF]

MITI Number	3-194	Category	Section 3
Chemical Substance Name	Chloroaniline
Remarks	-
Details	to J-CHECK
Remarks to Existing Chemical Substances of Industrial Safety and Health Act	Chemicals have been notified in accordance with the provisions of Chemical Substances Control Law by June 29, 1979
Details to Existing Chemical Substances of Industrial Safety and Health Act	to MHLW site (in Japanese)

Japan CSCL: Type II Monitoring Chemical Substances (before amendment) Data Description Import Clearance Procedures[PDF] Notification of the Manufacturing Amount, etc[PDF]
- Registration Number
  404
  Date of Designation in the Official Gazette 2000/09/22
  
  MITI Number
  3-194
  
  Chemical Substance Name p-Chloroaniline
  
  Remarks -
  
  Details to J-CHECK

Japan CSCL: Type III Monitoring Chemical Substances (before amendment) Data Description Import Clearance Procedures[PDF] Notification of the Manufacturing Amount, etc[PDF]
- Registration Number
  17
  Date of Designation in the Official Gazette 2006/07/18
  
  MITI Number
  3-194
  
  Chemical Substance Name p-Chloroaniline
  
  Remarks -
  
  Details to J-CHECK

Japan METI: Biodegradation and Bioconcentration Results Data Description

Chemical Substance Name	4-chloroaniline
Judgement of Biodegradation	Not readily biodegradable	Judgement of Bioconcentration	Low bioconcentration
Test result of Bioconcentration	-	Test result of Partition Coefficient	-
Details	to J-CHECK

Japan MOE: Results of Eco-toxicity tests of chemicals Data Description
- Chemical Substance Name p-Chloroaniline
  
  Details to J-CHECK

Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof(PRTR-SDS Law)

Japan: PRTR-SDS Law (until March 2023) Data Description Outline PRTR Law (METI site) Analysis of PRTR data

Classification	I	Cabinet Order Number	1-89
Cabinet Order Name	Chloroaniline
Remarks	-
Basis of selection	Hazard Data (in Japanese)
Link	Releases Map (in Japanese) Atmospheric concentration Map (in Japanese)

Japan: PRTR-SDS Law (from April 2023) Data Description Outline PRTR Law (METI site)

JPSN(Japan PRTR-SDS Number)	89	Classification	I	Cabinet Order Number	1-113
Cabinet Order Name	Chloroaniline
Remarks	-
Basis of selection	Hazard Data (in Japanese)
Link	- -

Industrial Safety and Health Act (ISHA)
- Japan ISHA: Chemical Substances Requiring Labeling and Delivery of Documents, etc. Data Description GHS compatible model label creation method (MH LW site : in Japanese) Risk assessment implementation support tool (MHLW site : in Japanese)
  - Cabinet Order Number
    Attached table 9-440 of Cabinet order
    
    Cabinet Order Name p-Chloroaniline
    
    Range of Application for Label (weight%) >=1
    
    Range of Application for SDS (weight%) >=0.1
- Japan ISHA: Chemical substances that cause skin disorders, etc. and other chemical substances that must be handled with impermeable protective equipment etc. based on special chemical regulations. Data Description Target substances list(MHLW site: in japanese)
  - Substance Name p-Chloroaniline
    
    Classification of Target Substances Skin Irritating Hazardous Substances Cutoff value(weight %) 1
    
    Implementation 2024/4/1
    
    Details to the GHS Classification
    
    Substance Name p-Chloroaniline
    
    Classification of Target Substances Skin Absorbing Hazardous Substances Cutoff value(weight %) 1
    
    Implementation 2024/4/1
    
    Details to the GHS Classification

Air Pollution Control Act
- Japan Air Pollution Control Law Data Description Air & Transportation (MOE site)
  - Classification Substances that may be classified as Hazardous Air Pollutants Cabinet Order Number
    50 of Central Environment Council 9th Report (Appendix 1)
    
    Cabinet Order Name Chloroaniline

Laws and Regulations in Other countries

Recommendations on the transport of dangerous goods
- Dangerous Goods List (UN Number and Hazard class) Data Description
  - UN Number
    2018
    Class or Division 6.1
    
    Name and Description CHLOROANILINES, SOLID
    
    UN packing group II
    
    UN Number
    2019
    Class or Division 6.1
    
    Name and Description CHLOROANILINES, LIQUID
    
    UN packing group II

Association of South-East Asian Nations(ASEAN)
- The ASEAN-Japan Chemical Safety Database (AJCSD).: Laws and Regulations Data Description
  - Detail to AJCSD

European Union (EU)

EC Inventory Data Description
- EC Number
  203-401-0
  
  EC Name 4-chloroaniline
  
  Description -
  
  Substance Infocard Infocard
  
  ECHA Name -

EU: CLP Harmonised Classification Data Description To ECHA site

Index Number	612-137-00-9	EC Number	203-401-0
Chemical Name	4-chloroaniline
Classification	Carc. 1B / [Inh.]Acute Tox. 3 * / [Der.]Acute Tox. 3 * / [Oral]Acute Tox. 3 * / Skin Sens. 1 / Aquatic Acute 1 / Aquatic Chronic 1

US: Toxic Substances Control Act (TSCA)
- TSCA Inventory Data Description
  - TSCA Chemical Substance Name Benzenamine, 4-chloro-
    
    DEF -
    
    UVCB -
    
    FLAG -
    
    ACTIVITY ACTIVE

China
- China: Catalog of Hazardous Chemicals 2015 Data Description
  - Number
    1417
    
    Name 4-Chloroaniline
    
    Other Name p-Chloroaniline; p-Aminochlorobenzene
    
    Remarks -

Korea

Korea: ARECs (K-REACH); Existing Chemical Substances Data Description

KE Number	KE-05525
Category	Existing Chemical Substances (Domestically distributed commercial purpose before February 2, 1991.)
Chemical Substance Name	4-Chlorobenzeneamine ; p-Chloroaniline
Remarks	In the case of being hydrated, the resulting hydrate is also applicable.

Taiwan
- Taiwan: TCCSCA/OSHA; Existing Chemical Substances Data Description
  - English Name p-Chloroaniline
    
    Chinese Name -

Chemical Hazard and Risk Information

GHS Classification Results

NITE Japan-GHS Data Description
- Edition version_1
  
  Chemical Substance Name p-Chloroaniline
  
  Classification Result To the resut webpage To the Excel flie

GHS Classification Results by the Japanese Government Data Description GHS Information

Year of implementation /renewal	2006	ID	111_H18_new
Chemical Substance Name	p-Chloroaniline
Classification Result	To the resut webpage To the Excel flie

Year of implementation /renewal	2014	ID	- / R-119
Chemical Substance Name	p-Chloroaniline
Classification Result	To the resut webpage To the Excel flie
Remarks	The reclassification result of only environmental hazard classes. As for physical and health hazard classes, please see the result in FY2006.

MHLW:GHS Aligned Sample Label and SDS
- GHS Aligned Sample Label and SDS Data Description Information on GHS Aligned Sample Label and SDS (Workplace Safety Site)
  - Chemical Substance Name p-Chloroaniline
    
    Sample Label -
    
    Sample SDS to MHLW Website (in Japanese Only)

AIST: Relational Information System for Chemical Accidents Database(RISCAD)
- Relational Information System for Chemical Accidents Database(RISCAD) Data Description RISCAD (in Japanese)
  - Material ID 1654
    
    Name 4-chloroaniline
    
    Material Information to RISCAD

Hazard and Risk Assessment Reports etc. in Japan

Chemical Substances Hazard Assessment Report / Initial Risk Assessment Report Data Description Guidance for Initial Risk Assessment ver.1 (in Japanese) Guidance for Initial Risk Assessment ver.2 (in Japanese)

Report Number	No.79
Assessed Chemical Substance Name	p-Chloroaniline
Details	Hazard Assessment Report (in Japanese)	Date of publication/ renewal	2008/02
	Details Initial Risk Assessment Report (in Japanese)	Date of publication/ renewal	2007/01
	Details Summary of Initial Risk Assessment Report	Date of publication/ renewal	2010/05

ISHA: Examples of Occupational Accidents Caused by Chemical Substances Data Description
- Name p-Chloroaniline (synonym: PCA)
  
  Examples of Occupational Accidents to MHLW site (in Japanese)

Hazard Data Sheet for Chemical Substances Data Description
- Book Number
  2000-30
  Date of publication/ renewal 2002/10
  
  Assessed Chemical Substance Name p-Chloroaniline
  
  Details Hazard Data Sheet (in Japanese)

Hazard and Risk Assessment Reports etc. in Other Countries
- International Chemical Safety Cards (ICSC) Data Description
  - ICSC Number
    26
    
    ICSC Title 4-Chloroaniline
    
    Details to ILO site
- Concise International Chemical Assessment Documents (CICADs) Data Description
  - CICADs Number
    48
    
    CICADs Title Chloroaniline, 4- (CICADS 48, 2003)
    
    Details to IPCS site
- US EPA: Integrated Risk Information System (IRIS) Data Description
  - Chemical Substance Name p-Chloroaniline
    
    Details to EPA site Last Revision 1988/08/22
- Advisory Committee on Existing Chemicals (BUA) Reports by the German Chemical Society Data Description
  - BUA Number
    153
    
    Substance Name 4-Chloroaniline
    
    Related information to BUA site

Japan Society for Occupational Health (JSOH) Recommendation of Occupational Exposure Limits
- JSOH: Occupational Carcinogens Data Description
  - Substance Name p-Chloroaniline
    
    Carcinogenicity classification 2B
    
    Details -
    
    Year of proposal 1995
    
    Remarks -

Carcinogenicity Assessment
- IARC: Carcinogenicity Assessment Data Description to IARC site
  - Volume 57 Volume publication year 1993
    
    Agent Name para-Chloroaniline
    
    Group 2B
    
    Details Vol.57 - - - -
- European Union (EU): Carcinogenicity Assessment Data Description to ECHA site
  - Substance Name 4-chloroaniline
    
    Category Code 1B

Test Data and Reports

Japan METI: Biodegradation and Bioconcentration Results Data Description

Chemical Substance Name	4-chloroaniline
Judgement of Biodegradation	Not readily biodegradable	Judgement of Bioconcentration	Low bioconcentration
Test result of Bioconcentration	-	Test result of Partition Coefficient	-
Details	to J-CHECK

Japan MOE: Results of Eco-toxicity tests of chemicals Data Description
- Chemical Substance Name p-Chloroaniline
  
  Details to J-CHECK

US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts Data Description
- Report Number
  TR-189
  
  Report Title Bioassay of p-Chloroaniline for Possible Carcinogenicity (CASRN 106-47-8)
  
  Abstract to NTP site Full Text to NTP site

CHRIP_ID	C004-661-64A	CAS RN	106-47-8
Chemical Substance Name	4-Chloroaniline
Molecular Formula	C6H6ClN
Molecular Weight	128
SMILES	ClC1=CC=C(C=C1)N
Structure

Synonym	Benzenamine, 4-chloro-
	Chloroaminobenzene, p-
	Chloroaniline, p-
	p-Chloroaniline
	para-Chloroaniline

Registration Number	404	Date of Designation in the Official Gazette	2000/09/22
MITI Number	3-194
Chemical Substance Name	p-Chloroaniline
Remarks	-
Details	to J-CHECK

Registration Number	17	Date of Designation in the Official Gazette	2006/07/18
MITI Number	3-194
Chemical Substance Name	p-Chloroaniline
Remarks	-
Details	to J-CHECK

Cabinet Order Number	Attached table 9-440 of Cabinet order
Cabinet Order Name	p-Chloroaniline
Range of Application for Label (weight%)	>=1
Range of Application for SDS (weight%)	>=0.1

Substance Name	p-Chloroaniline
Classification of Target Substances	Skin Irritating Hazardous Substances	Cutoff value(weight %)	1
Implementation	2024/4/1
Details	to the GHS Classification

Classification	Substances that may be classified as Hazardous Air Pollutants	Cabinet Order Number	50 of Central Environment Council 9th Report (Appendix 1)
Cabinet Order Name	Chloroaniline

UN Number	2018	Class or Division	6.1
Name and Description	CHLOROANILINES, SOLID
UN packing group	II

UN Number	2019	Class or Division	6.1
Name and Description	CHLOROANILINES, LIQUID
UN packing group	II

EC Number	203-401-0
EC Name	4-chloroaniline
Description	-
Substance Infocard	Infocard
ECHA Name	-

TSCA Chemical Substance Name	Benzenamine, 4-chloro-
DEF	-
UVCB	-
FLAG	-
ACTIVITY	ACTIVE

Material ID	1654
Name	4-chloroaniline
Material Information	to RISCAD

ICSC Number	26
ICSC Title	4-Chloroaniline
Details	to ILO site

CICADs Number	48
CICADs Title	Chloroaniline, 4- (CICADS 48, 2003)
Details	to IPCS site

Number	1417
Name	4-Chloroaniline
Other Name	p-Chloroaniline; p-Aminochlorobenzene
Remarks	-

Edition	version_1
Chemical Substance Name	p-Chloroaniline
Classification Result	To the resut webpage To the Excel flie

Chemical Substance Name	p-Chloroaniline
Sample Label	-
Sample SDS	to MHLW Website (in Japanese Only)

Name	p-Chloroaniline (synonym: PCA)
Examples of Occupational Accidents	to MHLW site (in Japanese)

Book Number	2000-30	Date of publication/ renewal	2002/10
Assessed Chemical Substance Name	p-Chloroaniline
Details	Hazard Data Sheet (in Japanese)

BUA Number	153
Substance Name	4-Chloroaniline
Related information	to BUA site

Substance Name	p-Chloroaniline
Carcinogenicity classification	2B
Details	-
Year of proposal	1995
Remarks	-

Volume	57	Volume publication year	1993
Agent Name	para-Chloroaniline
Group	2B
Details	Vol.57 - - - -

Report Number	TR-189
Report Title	Bioassay of p-Chloroaniline for Possible Carcinogenicity (CASRN 106-47-8)
Abstract	to NTP site	Full Text	to NTP site