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General Information
- General Information
  - General Information Data Description
    - CHRIP_ID C004-664-82A CAS RN 75-09-2
      
      Chemical Substance Name Dichloromethane
      
      Molecular Formula CH2Cl2
      
      Molecular Weight 85
      
      SMILES ClCCl
      
      Structure
- Synonym
  - Synonym Data Description
    - Synonym Methylene chloride
      
      DCM
      
      Dichloromethane (Methylene chloride)
      
      Dichloromethane; Methylene dichloride
      
      methane, dichloro-
      
      Methylene chloride
      
      Methylene dichloride
- Nikkaji
  - Information of Japan Chemical Substance Dictionary (Nikkaji) Data Description
    - Nikkaji Number
      J2.389B
      Detail to J-GLOBAL

Laws and Regulations in Japan

Act on the Evaluation of Chemical Substances and Regulation of Their Manufacture, etc. (Chemical Substances Control Law ; CSCL)

Japan CSCL: Canceled Priority Assessment Chemical Substances Data Description

Registration Number	7	Date of Cancellation	2017/03/30
MITI Number	2-36	Date of designation as a priority assessment chemical substance	2011/04/01
Chemical Substance Name	Dichloromethane (synonym: Methylene chloride)
Remarks	-
Remarks of Cancellation	-
Details	to J-CHECK

Japan CSCL: Existing Chemical Substances Data Description Definition of the terms of Section 6 [PDF] Definition of the terms of Section 7 [PDF] Import Clearance Procedures[PDF] Notification of the Manufacturing Amount, etc[PDF]

MITI Number	2-36	Category	Section 2
Chemical Substance Name	Methylene chloride
Remarks	-
Details	to J-CHECK
Remarks to Existing Chemical Substances of Industrial Safety and Health Act	Chemicals have been notified in accordance with the provisions of Chemical Substances Control Law by June 29, 1979
Details to Existing Chemical Substances of Industrial Safety and Health Act	to MHLW site (in Japanese)

Japan CSCL: Type II Monitoring Chemical Substances (before amendment) Data Description Import Clearance Procedures[PDF] Notification of the Manufacturing Amount, etc[PDF]

Registration Number	371	Date of Designation in the Official Gazette	2000/09/22
MITI Number	2-36
Chemical Substance Name	Dichloromethane (synonym: Methylene chloride)
Remarks	-
Details	to J-CHECK

Japan CSCL: Type III Monitoring Chemical Substances (before amendment) Data Description Import Clearance Procedures[PDF] Notification of the Manufacturing Amount, etc[PDF]

Registration Number	160	Date of Designation in the Official Gazette	2010/03/19
MITI Number	2-36
Chemical Substance Name	Dichloromethane (synonym: Methylene chloride)
Remarks	-
Details	to J-CHECK

Japan METI: Biodegradation and Bioconcentration Results Data Description

Chemical Substance Name	dichloromethane
Judgement of Biodegradation	Not readily biodegradable	Judgement of Bioconcentration	Low bioconcentration
Test result of Bioconcentration	-	Test result of Partition Coefficient	-
Details	to J-CHECK

Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof(PRTR-SDS Law)

Japan: PRTR-SDS Law (until March 2023) Data Description Outline PRTR Law (METI site) Analysis of PRTR data

Classification	I	Cabinet Order Number	1-186
Cabinet Order Name	Dichloromethane (synonym: Methylene chloride)
Remarks	-
Basis of selection	Hazard Data (in Japanese)
Link	Releases Map (in Japanese) Atmospheric concentration Map (in Japanese)

Japan: PRTR-SDS Law (from April 2023) Data Description Outline PRTR Law (METI site)

JPSN(Japan PRTR-SDS Number)	186	Classification	I	Cabinet Order Number	1-213
Cabinet Order Name	Dichloromethane (synonym: Methylene chloride)
Remarks	-
Basis of selection	Hazard Data (in Japanese)
Link	- -

Industrial Safety and Health Act (ISHA)

Japan ISHA: Chemical Substances Requiring Labeling and Delivery of Documents, etc. Data Description GHS compatible model label creation method (MH LW site : in Japanese) Risk assessment implementation support tool (MHLW site : in Japanese)

Cabinet Order Number	Attached table 9-257 of Cabinet order
Cabinet Order Name	Dichloromethane(otherwise known as Methylene dichloride)
Range of Application for Label (weight%)	>=1
Range of Application for SDS (weight%)	>=0.1

Japan ISHA: Chemical substances that cause skin disorders, etc. and other chemical substances that must be handled with impermeable protective equipment etc. based on special chemical regulations. Data Description Target substances list(MHLW site: in japanese)
- Substance Name Dichloromethane (synonym: Methylene dichloride)
  
  Classification of Target Substances Special chemical regulations etc. Cutoff value(weight %) 1
  
  Details to the GHS Classification

Japan ISHA: Specified Chemical Substances Data Description Link to the Ordinance (JISHA site : in Japanese)

Category	Group-2 substances	Cabinet Order Number	Attached Table 3-2-19-3 of Cabinet order
Cabinet Order Name	Dichloromethane (synonym: methylene dichloride)
Range of Application (weight %)	>1
Remarks	Substances under special supervision / Special organic solvent, etc.

The above information have been provided by the Ministry of Health, Labour and Welfare

Japan ISHA: Administrative Control Levels of Working Environment Evaluation Standards Data Description Working Environment Measurement (MHLW site : in Japanese)
- Registration Number
  17.3
  
  Kinds of substances Dichloromethane (otherwise known as methylene dichloride)
  
  Control Level 50ppm
  
  The above information have been provided by the Ministry of Health, Labour and Welfare

Japan ISHA: Guidelines for Carcinogenic Substances Data Description
- Name Dichloromethane
  
  Details to MHLW site (in Japanese)

Japan ISHA: Strong Mutagenic Chemical Substances Data Description Related information (MHLW site : in Japanese)
- Classification Existing Chemical Substances
  
  Name Methylene chloride
  
  Date of Notification 1997/12/14 Appendix2(4)

Air Pollution Control Act

Japan Air Pollution Control Law Data Description Air & Transportation (MOE site)

Classification	Volatile Organic Compounds (VOC)	Cabinet Order Number	Article 2-4 of Act
Cabinet Order Name	Any organic compound (excluding substances specified by a Cabinet Order as not being sources from which suspended particulate matter or oxidants are generated) that is in a gaseous state at the time of its emission or dispersal into the atmosphere.
VOC Emission Inventory Substance Code	62-01-02
VOC Emission Inventory Substance Name	Dichloromethane

Classification	Substances that may be classified as Hazardous Air Pollutants	Cabinet Order Number	85 of Central Environment Council 9th Report (Appendix 1)
Cabinet Order Name	Dichloromethane; Methylene dichloride

Classification	Substances that may be classified as Hazardous Air Pollutants (Priority Action Substances)	Cabinet Order Number	10 of Central Environment Council 9th Report (Appendix 2)
Cabinet Order Name	Dichloromethane; Methylene dichloride

Water Pollution Prevention Act
- Japan Water Pollution Control Law Data Description Water / Soil / Ground Environment (MOE site)
  - Classification Harmful Substances Cabinet Order Number
    Article 2-11 of Cabinet order
    
    Cabinet Order Name Dichloromethane
    
    Effluent Standards 0.2mg/L

Soil Contamination Countermeasures Act
- Japan Soil Contamination Countermeasures Act Data Description Water / Soil / Ground Environment (MOE site)
  - Classification Class 1 Cabinet Order Number
    Article 1-12 of Cabinet order
    
    Cabinet Order Name Dichloromethane
    
    Soil Leachate Standard 0.02mg/L
    
    Soil Concentration Standard -

Laws and Regulations in Other countries

Recommendations on the transport of dangerous goods
- Dangerous Goods List (UN Number and Hazard class) Data Description
  - UN Number
    1593
    Class or Division 6.1
    
    Name and Description DICHLOROMETHANE
    
    UN packing group III
    
    UN Number
    1912
    Class or Division 2.1
    
    Name and Description METHYL CHLORIDE AND METHYLENE CHLORIDE MIXTURE

International Convention on the Commodity Description and Coding Systems (HS Convention)

HS Code: Section VI “Products of the Chemical or Allied Industries" Data Description

Chapter	29	Chapter name	Organic chemicals
Heading	2903	Substance name (Heading)	Halogenated derivatives of hydrocarbons
HS Code	2903.12	Substance Name	Saturated chlorinated derivatives of acyclic hydrocarbons : Dichloromethane (methylene chloride)

Association of South-East Asian Nations(ASEAN)
- The ASEAN-Japan Chemical Safety Database (AJCSD).: Laws and Regulations Data Description
  - Detail to AJCSD
- The ASEAN-Japan Chemical Safety Database (AJCSD).: GHS-Related Information Data Description
  - Detail to AJCSD

European Union (EU)
- EC Inventory Data Description
  - EC Number
    200-838-9
    
    EC Name Dichloromethane
    
    Description -
    
    Substance Infocard Infocard
    
    ECHA Name dichloromethane; methylene chloride
- EU: CLP Harmonised Classification Data Description To ECHA site
  - Index Number 602-004-00-3 EC Number 200-838-9
    
    Chemical Name dichloromethane; methylene chloride
    
    Classification Carc. 2

US: Toxic Substances Control Act (TSCA)

TSCA Inventory Data Description
- TSCA Chemical Substance Name Methane, dichloro-
  
  DEF -
  
  UVCB -
  
  FLAG R
  
  ACTIVITY ACTIVE

TSCA: Prioritization, risk evaluation, and regulation of chemical substances and mixtures Data Description

CFR Number	40 CFR 751 Subpart B
Name in TSCA regulation	Methylene chloride
Remarks	Regulation of Certain Chemical Substances and Mixtures Under Section 6 of the Toxic Substances Control Act / Consumer paint and coating removal.

China
- China: Catalog of Hazardous Chemicals 2015 Data Description
  - Number
    541
    
    Name Dichloromethane
    
    Other Name Methylene chloride
    
    Remarks -

Korea

Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances Data Description
- Number
  2019-1-931
  
  Category Toxic Substance(s)
  
  Chemical Substance Name Methylene chloride
  
  Range of Application (%)
  >=0.1
  
  Number
  30
  
  Category Priority Control Substances
  
  Chemical Substance Name Dichloromethane

Korea: ARECs (K-REACH); Existing Chemical Substances Data Description

KE Number	KE-23893
Category	Existing Chemical Substances (Domestically distributed commercial purpose before February 2, 1991.)
Chemical Substance Name	Dichloromethane
Remarks	In the case of being hydrated, the resulting hydrate is also applicable.

Korea: ARECs (K-REACH); Others Data Description

Number	29
Category	Phase-in substance(s) subject to registration (by June 30, 2018)
Chemical Substance Name	Methylene chloride; Dichloromethane
Note	The registration grace period is until June 30, 2018

Taiwan

Taiwan: TCCSCA/OSHA; Existing Chemical Substances Data Description
- English Name dichloromethane
  
  Chinese Name -

Taiwan: TCCSCA; Toxic Chemicals Data Description

Listed No./Series No.	79/01
Toxicity Classify	4
English Name	Dichloromethane(Methylenechloride)
Chinese Name	二氯甲烷
Control concentration standard (w/w%)	25
Large-scale handling standard(kg)	-

Chemical Hazard and Risk Information

GHS Classification Results
- NITE Japan-GHS Data Description
  - Edition version_1
    
    Chemical Substance Name Dichloromethane
    
    Classification Result To the resut webpage To the Excel flie
- GHS Classification Results by the Japanese Government Data Description GHS Information
  - Year of implementation /renewal 2006 ID 141_H18_new
    
    Chemical Substance Name Dichloromethane; Methylene dichloride
    
    Classification Result To the resut webpage To the Excel flie
    
    Year of implementation /renewal 2017 ID H29-B-064
    
    Chemical Substance Name Dichloromethane
    
    Classification Result To the resut webpage To the Excel flie

MHLW:GHS Aligned Sample Label and SDS
- GHS Aligned Sample Label and SDS Data Description Information on GHS Aligned Sample Label and SDS (Workplace Safety Site)
  - Chemical Substance Name Dichloromethane
    
    Sample Label to MHLW Website (in Japanese Only)
    
    Sample SDS to MHLW Website (in Japanese Only)

AIST: Relational Information System for Chemical Accidents Database(RISCAD)
- Relational Information System for Chemical Accidents Database(RISCAD) Data Description RISCAD (in Japanese)
  - Material ID 299
    
    Name dichloromethane
    
    Material Information to RISCAD

Hazard and Risk Assessment Reports etc. in Japan

Chemical Substances Hazard Assessment Report / Initial Risk Assessment Report Data Description Guidance for Initial Risk Assessment ver.1 (in Japanese) Guidance for Initial Risk Assessment ver.2 (in Japanese)

Report Number	No.15
Assessed Chemical Substance Name	Dichloromethane
Details	Hazard Assessment Report (in Japanese)	Date of publication/ renewal	2004/09
	Details Initial Risk Assessment Report (in Japanese)	Date of publication/ renewal	2007/01
	Details Summary of Initial Risk Assessment Report	Date of publication/ renewal	2010/05

ISHA: Examples of Occupational Accidents Caused by Chemical Substances Data Description
- Name Dichloromethane (synonym: Methylene dichloride)
  
  Examples of Occupational Accidents to MHLW site (in Japanese)

Hazard Data Sheet for Chemical Substances Data Description
- Book Number
  96-2
  Date of publication/ renewal 1997/07
  
  Assessed Chemical Substance Name Dichloromethane
  
  Details Hazard Data Sheet (in Japanese)

CSCL: The Japan HPV Challenge Program Data Description
- Chemical Substance Name Dichloromethane
  
  Details to J-CHECK

Hazard and Risk Assessment Reports etc. in Other Countries
- OECD: High Production Volume (HPV) Chemicals Data Description
  - Chemical Name Methane, dichloro-
    
    Details to OECD Existing Chemicals Database
- International Chemical Safety Cards (ICSC) Data Description
  - ICSC Number
    58
    
    ICSC Title Dichloromethane
    
    Details to ILO site
- Environmental Health Criteria (EHC) Data Description
  - EHC Number
    32
    
    EHC Title Methylene chloride
    
    Details to IPCS site
    
    EHC Number
    164
    
    EHC Title Methylene chloride (Second edition)
    
    Details to IPCS site
- US Agency for Toxic Substances and Disease Registry (ATSDR): Toxicological Profiles Data Description
  - Profile Title Methylene Chloride
    
    Details to ATSDR site
    
    Date of Issue September 2000
- US EPA: Integrated Risk Information System (IRIS) Data Description
  - Chemical Substance Name Dichloromethane
    
    Details to EPA site Last Revision 2011/11/18
- US EPA: Acute Exposure Guideline Levels (AEGLs) Data Description
  - Chemical Name Methylene chloride
    
    Status Interim
    
    AEGL Values to EPA site
- Advisory Committee on Existing Chemicals (BUA) Reports by the German Chemical Society Data Description
  - BUA Number
    6
    
    Substance Name Dichloromethane
    
    Related information to BUA site
- Canada: Priority Substances List (PSL) Data Description
  - Type of Priory Substances List PSL1
    
    Report Title Dichloromethane
    
    Details to Environment Canada site

Japan Society for Occupational Health (JSOH) Recommendation of Occupational Exposure Limits

JSOH: Occupational Exposure Limits Data Description

Substance Name	Dichloromethane
Occupational Exposure Limit (ppm)	50, 100 (Occupational Exposure Limit-Ceiling)
Occupational Exposure Limit (mg/m3)	173, 347 (Occupational Exposure Limit-Ceiling)
Details	Documentation in Japanese
Year of proposal	1999
Remarks	Skin absorption

JSOH: Occupational Exposure Limits Based on Biological Monitoring Data Description TableII-1
- Substance Name Dichloromethane
  
  Details Documentation in Japanese
  
  Year of proposal 2005
  
  Remarks -

JSOH: Occupational Carcinogens Data Description
- Substance Name Dichloromethane
  
  Carcinogenicity classification 2A
  
  Details Documentation in Japanese
  
  Year of proposal 1991, 2014, 2015
  
  Remarks -

Carcinogenicity Assessment
- IARC: Carcinogenicity Assessment Data Description to IARC site
  - Volume Sup 7, 71, 110 Volume publication year 2017
    
    Agent Name Dichloromethane (Methylene chloride)
    
    Group 2A
    
    Details Sup 7 Vol.71 Vol.110 - -
- US EPA: Carcinogenicity Assessment Data Description to EPA site
  - Chemical Substance Name Dichloromethane
    
    Guideline: Category 2005 : L
    
    Exporsure Route Oral route, Inhalation route
    
    Details to Substance Profile
- US NTP: Carcinogenicity Assessment Data Description to NTP site
  - Chemical Substance Name Dichloromethane
    
    Category
    RAHC
    
    NAME OR SYNONYM
    Dichloromethane
    
    Details to Substance Profile
- European Union (EU): Carcinogenicity Assessment Data Description to ECHA site
  - Substance Name dichloromethane; methylene chloride
    
    Category Code 2

Test Data and Reports

Japan METI: Biodegradation and Bioconcentration Results Data Description

Chemical Substance Name	dichloromethane
Judgement of Biodegradation	Not readily biodegradable	Judgement of Bioconcentration	Low bioconcentration
Test result of Bioconcentration	-	Test result of Partition Coefficient	-
Details	to J-CHECK

ISHA: Carcinogenicity Test Results for Chemical Substances Data Description to MHLW site (in Japanese)
- Chemical Name Dichloromethane
  
  Summary Inhalation test results (in Japanese)

ISHA: Mutagenicity Test Results for Chemical Substances Data Description to MHLW site (in Japanese)
- Chemical Name Methylenechloride(Gas)
  
  Bacterial Test Positive
  
  CHL/IU Test -

US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts Data Description

Report Number	TR-306
Report Title	Toxicology and Carcinogenesis Studies of Dichloromethane (Methylene Chloride) (CASRN 75-09-2) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
Abstract	to NTP site	Full Text	to NTP site

CHRIP_ID	C004-664-82A	CAS RN	75-09-2
Chemical Substance Name	Dichloromethane
Molecular Formula	CH2Cl2
Molecular Weight	85
SMILES	ClCCl
Structure

Synonym	Methylene chloride
	DCM
	Dichloromethane (Methylene chloride)
	Dichloromethane; Methylene dichloride
	methane, dichloro-
	Methylene chloride
	Methylene dichloride

Substance Name	Dichloromethane (synonym: Methylene dichloride)
Classification of Target Substances	Special chemical regulations etc.	Cutoff value(weight %)	1
Details	to the GHS Classification

Registration Number	17.3
Kinds of substances	Dichloromethane (otherwise known as methylene dichloride)
Control Level	50ppm

Classification	Existing Chemical Substances
Name	Methylene chloride
Date of Notification	1997/12/14 Appendix2(4)

Classification	Harmful Substances	Cabinet Order Number	Article 2-11 of Cabinet order
Cabinet Order Name	Dichloromethane
Effluent Standards	0.2mg/L

Classification	Class 1	Cabinet Order Number	Article 1-12 of Cabinet order
Cabinet Order Name	Dichloromethane
Soil Leachate Standard	0.02mg/L
Soil Concentration Standard	-

UN Number	1593	Class or Division	6.1
Name and Description	DICHLOROMETHANE
UN packing group	III

UN Number	1912	Class or Division	2.1
Name and Description	METHYL CHLORIDE AND METHYLENE CHLORIDE MIXTURE

EC Number	200-838-9
EC Name	Dichloromethane
Description	-
Substance Infocard	Infocard
ECHA Name	dichloromethane; methylene chloride

TSCA Chemical Substance Name	Methane, dichloro-
DEF	-
UVCB	-
FLAG	R
ACTIVITY	ACTIVE

Index Number	602-004-00-3	EC Number	200-838-9
Chemical Name	dichloromethane; methylene chloride
Classification	Carc. 2

Number	2019-1-931
Category	Toxic Substance(s)
Chemical Substance Name	Methylene chloride
Range of Application (%)	>=0.1

Number	30
Category	Priority Control Substances
Chemical Substance Name	Dichloromethane

Edition	version_1
Chemical Substance Name	Dichloromethane
Classification Result	To the resut webpage To the Excel flie

Year of implementation /renewal	2006	ID	141_H18_new
Chemical Substance Name	Dichloromethane; Methylene dichloride
Classification Result	To the resut webpage To the Excel flie

Year of implementation /renewal	2017	ID	H29-B-064
Chemical Substance Name	Dichloromethane
Classification Result	To the resut webpage To the Excel flie

Chemical Substance Name	Dichloromethane
Sample Label	to MHLW Website (in Japanese Only)
Sample SDS	to MHLW Website (in Japanese Only)

Material ID	299
Name	dichloromethane
Material Information	to RISCAD

Name	Dichloromethane (synonym: Methylene dichloride)
Examples of Occupational Accidents	to MHLW site (in Japanese)

Book Number	96-2	Date of publication/ renewal	1997/07
Assessed Chemical Substance Name	Dichloromethane
Details	Hazard Data Sheet (in Japanese)

EHC Number	164
EHC Title	Methylene chloride (Second edition)
Details	to IPCS site

Profile Title	Methylene Chloride
Details	to ATSDR site
Date of Issue	September 2000

Chemical Name	Methylene chloride
Status	Interim
AEGL Values	to EPA site

BUA Number	6
Substance Name	Dichloromethane
Related information	to BUA site

Type of Priory Substances List	PSL1
Report Title	Dichloromethane
Details	to Environment Canada site

Substance Name	Dichloromethane
Carcinogenicity classification	2A
Details	Documentation in Japanese
Year of proposal	1991, 2014, 2015
Remarks	-

Volume	Sup 7, 71, 110	Volume publication year	2017
Agent Name	Dichloromethane (Methylene chloride)
Group	2A
Details	Sup 7 Vol.71 Vol.110 - -

Chemical Substance Name	Dichloromethane
Guideline: Category	2005 : L
Exporsure Route	Oral route, Inhalation route
Details	to Substance Profile

Substance Name	dichloromethane; methylene chloride
Category Code	2

Chemical Name	Dichloromethane
Summary	Inhalation test results (in Japanese)