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General Information
- General Information
  - General Information Data Description
    - CHRIP_ID C004-668-13A CAS RN 79-06-1
      
      Chemical Substance Name Acrylamide
      
      Molecular Formula C3H5NO
      
      Molecular Weight 71
      
      SMILES NC(C=C)=O
      
      Structure
- Synonym
  - Synonym Data Description
    - Synonym Acrylamide
      
      2-propenamide
      
      2-Propene amide
      
      Acrylic acid amide
      
      Prop-2-enamide
      
      Vinyl amide
- Nikkaji
  - Information of Japan Chemical Substance Dictionary (Nikkaji) Data Description
    - Nikkaji Number
      J2.408B
      Detail to J-GLOBAL

Laws and Regulations in Japan

Act on the Evaluation of Chemical Substances and Regulation of Their Manufacture, etc. (Chemical Substances Control Law ; CSCL)

Japan CSCL: Priority Assessment Chemical Substances Data Description Import Clearance Procedures[PDF] Notification of the Manufacturing Amount, etc[PDF]
- Registration Number
  34
  Date of Designation 2011/04/01
  
  MITI Number
  2-1014
  
  Chemical Substance Name Acrylamide
  
  Reason for Inclusion Human Health
  
  Remarks -
  
  Details to J-CHECK

Japan CSCL: Existing Chemical Substances Data Description Definition of the terms of Section 6 [PDF] Definition of the terms of Section 7 [PDF] Import Clearance Procedures[PDF] Notification of the Manufacturing Amount, etc[PDF]

MITI Number	2-1014	Category	Section 2
Chemical Substance Name	Acrylamide
Remarks	-
Details	to J-CHECK
Remarks to Existing Chemical Substances of Industrial Safety and Health Act	Chemicals have been notified in accordance with the provisions of Chemical Substances Control Law by June 29, 1979
Details to Existing Chemical Substances of Industrial Safety and Health Act	to MHLW site (in Japanese)

Japan CSCL: Type II Monitoring Chemical Substances (before amendment) Data Description Import Clearance Procedures[PDF] Notification of the Manufacturing Amount, etc[PDF]
- Registration Number
  1046
  Date of Designation in the Official Gazette 2010/04/01
  
  MITI Number
  2-1014
  
  Chemical Substance Name Acrylamide
  
  Remarks -
  
  Details to J-CHECK

Japan METI: Biodegradation and Bioconcentration Results Data Description

Chemical Substance Name	acrylamide
Judgement of Biodegradation	Readily biodegradable	Judgement of Bioconcentration	-
Test result of Bioconcentration	-	Test result of Partition Coefficient	-
Details	to J-CHECK

Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof(PRTR-SDS Law)

Japan: PRTR-SDS Law (until March 2023) Data Description Outline PRTR Law (METI site) Analysis of PRTR data

Classification	I	Cabinet Order Number	1-2
Cabinet Order Name	Acrylamide
Remarks	-
Basis of selection	Hazard Data (in Japanese)
Link	Releases Map (in Japanese) Atmospheric concentration Map (in Japanese)

Japan: PRTR-SDS Law (from April 2023) Data Description Outline PRTR Law (METI site)

JPSN(Japan PRTR-SDS Number)	2	Classification	I	Cabinet Order Number	1-003
Cabinet Order Name	Acrylamide
Remarks	-
Basis of selection	Hazard Data (in Japanese)
Link	- -

Industrial Safety and Health Act (ISHA)
- Japan ISHA: Chemical Substances Requiring Labeling and Delivery of Documents, etc. Data Description GHS compatible model label creation method (MH LW site : in Japanese) Risk assessment implementation support tool (MHLW site : in Japanese)
  - Cabinet Order Number
    Attached table 9-1 of Cabinet order
    
    Cabinet Order Name Acrylamide
    
    Range of Application for Label (weight%) >=0.1
    
    Range of Application for SDS (weight%) >=0.1
- Japan ISHA: Carcinogenic Substances (Ordinance on Industrial Safety and Health) (subject to 30-year storage of work records, etc.) Data Description Lists of Target Substances (MHLW site : in Japanese)
  - GHS Classification Substance Name Acrylamide
    
    Carcinogenicity in GHS classification Category 1B Range of Application (weight%) >=0.1
    
    Implementation
    2023/4/1
    
    Details to the GHS Classification
- Japan ISHA: Chemical substances that cause skin disorders, etc. and other chemical substances that must be handled with impermeable protective equipment etc. based on special chemical regulations. Data Description Target substances list(MHLW site: in japanese)
  - Substance Name Acrylamide
    
    Classification of Target Substances Special chemical regulations etc. Cutoff value(weight %) 1
    
    Details to the GHS Classification
- Japan ISHA: Specified Chemical Substances Data Description Link to the Ordinance (JISHA site : in Japanese)
  - Category Group-2 substances Cabinet Order Number
    Attached Table 3-2-1 of Cabinet order
    
    Cabinet Order Name Acrylamide
    
    Range of Application (weight %) >1
    
    Remarks Specified Group-2 substances
    
    The above information have been provided by the Ministry of Health, Labour and Welfare
- Japan ISHA: Administrative Control Levels of Working Environment Evaluation Standards Data Description Working Environment Measurement (MHLW site : in Japanese)
  - Registration Number
    2
    
    Kinds of substances Acrylamide
    
    Control Level 0.1mg/m3
    
    The above information have been provided by the Ministry of Health, Labour and Welfare
- Japan ISHA: Strong Mutagenic Chemical Substances Data Description Related information (MHLW site : in Japanese)
  - Classification Existing Chemical Substances
    
    Name Acrylamide
    
    Date of Notification 2004/08/27 Appendix2(1)

Poisonous and Deleterious Substances Control Act
- Japan Poisonous and Deleterious Substances Control Act Data Description Link to the Act (MOJ site)
  - Classification Deleterious Substances(Cabinet order) Law or Cabinet Order Number
    Article 2-1-1-3 of Cabinet order
    
    Law or Cabinet Order Name Acrylamide and preparations containing it

Air Pollution Control Act
- Japan Air Pollution Control Law Data Description Air & Transportation (MOE site)
  - Classification Substances that may be classified as Hazardous Air Pollutants Cabinet Order Number
    2 of Central Environment Council 9th Report (Appendix 1)
    
    Cabinet Order Name Acrylamide

Water Pollution Prevention Act
- Japan Water Pollution Control Law Data Description Water / Soil / Ground Environment (MOE site)
  - Classification Designated Substances Cabinet Order Number
    Article 3-3-9 of Cabinet order
    
    Cabinet Order Name Acrylamide

Food Sanitation Act

Food Sanitation Act: Table 1 (2) in Appended table 1 of Specifications and Standards Notification; Base polymers (Coatings) Data Description The positive list system for food utensils, containers and packaging (MHLW)

Category	4. Vinyl polymer
Number Name	21. Copolymer composed of vinyl acetate with following one or more monomers; 1)acrylamide
Food category (Ac\|Fa\|Mi\|Al\|Ot)	○\|○\|○\|○\|○	Max. Temp./Synth. Resin Gr.	III/1,3
Requirements	Vinyl acetate: Not less than 50% in the base polymer components.

Food Sanitation Act: Table 1 (3) in Appended table 1 of Specifications and Standards Notification; Base polymers (Trace amount monomer) Data Description The positive list system for food utensils, containers and packaging (MHLW)
- Number Name 10. Organic nitrogen compound; 1)acrylamide

Fire Service Act

Fire Service Act : Substances that inhibit firefighting activities Data Description

Number of cabinet order etc.	HM Ordinance Article 1-10 (6) Attached Table 2(18), MIC Ordinance Article 2(5)
Substances	Acrylamide and preparations containing it
Stipulated quantity	200kg
Sources	MHLW Website; Sample SDS

Laws and Regulations in Other countries

Recommendations on the transport of dangerous goods
- Dangerous Goods List (UN Number and Hazard class) Data Description
  - UN Number
    2074
    Class or Division 6.1
    
    Name and Description ACRYLAMIDE, SOLID
    
    UN packing group III
    
    UN Number
    3426
    Class or Division 6.1
    
    Name and Description ACRYLAMIDE SOLUTION
    
    UN packing group III

Association of South-East Asian Nations(ASEAN)
- The ASEAN-Japan Chemical Safety Database (AJCSD).: Laws and Regulations Data Description
  - Detail to AJCSD
- The ASEAN-Japan Chemical Safety Database (AJCSD).: GHS-Related Information Data Description
  - Detail to AJCSD

European Union (EU)

EC Inventory Data Description
- EC Number
  201-173-7
  
  EC Name Acrylamide
  
  Description -
  
  Substance Infocard Infocard
  
  ECHA Name -

REACH: Substances of Very High Concern for Authorization (SVHC) Data Description
- EC Number 201-173-7 Status Candidate List
  
  Substance Name Acrylamide
  
  Reason for inclusion
  Carcinogenic (Article 57a) / Mutagenic (Article 57b)
  
  Date of inclusion
  2010/03/30
  
  Details to ECHA site

EU: CLP Harmonised Classification Data Description To ECHA site

Index Number	616-003-00-0	EC Number	201-173-7
Chemical Name	acrylamide; prop-2-enamide
Classification	Carc. 1B / Muta. 1B / Repr. 2 / [Oral]Acute Tox. 3 * / STOT RE 1 / [Inh.]Acute Tox. 4 * / [Der.]Acute Tox. 4 * / Eye Irrit. 2 / Skin Irrit. 2 / Skin Sens. 1
Notes and conditions	Note D

US: Toxic Substances Control Act (TSCA)
- TSCA Inventory Data Description
  - TSCA Chemical Substance Name 2-Propenamide
    
    DEF -
    
    UVCB -
    
    FLAG -
    
    ACTIVITY ACTIVE

China
- China: Catalog of Hazardous Chemicals 2015 Data Description
  - Number
    154
    
    Name Propenamide
    
    Other Name -
    
    Remarks -

Korea

Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances Data Description
- Number
  97-1-171
  
  Category Toxic Substance(s)
  
  Chemical Substance Name Acrylamide
  
  Range of Application (%)
  >=0.1
  
  Number
  06-5-14
  
  Category Restricted Substance(s)
  
  Chemical Substance Name Acrylamide
  
  Range of Application (%)
  >=0.1
  
  Number
  41
  
  Category Priority Control Substances
  
  Chemical Substance Name Acrylamide

Korea: ARECs (K-REACH); Existing Chemical Substances Data Description

KE Number	KE-29374
Category	Existing Chemical Substances (Domestically distributed commercial purpose before February 2, 1991.)
Chemical Substance Name	2-Propenamide ; Acrylamide
Remarks	In the case of being hydrated, the resulting hydrate is also applicable.

Korea: ARECs (K-REACH); Others Data Description
- Number 47
  
  Category Phase-in substance(s) subject to registration (by June 30, 2018)
  
  Chemical Substance Name 2-Propenamide; Acrylamide
  
  Note
  The registration grace period is until June 30, 2018

Taiwan
- Taiwan: TCCSCA/OSHA; Existing Chemical Substances Data Description
  - English Name acrylamide
    
    Chinese Name -
- Taiwan: TCCSCA; Toxic Chemicals Data Description
  - Listed No./Series No. 50/01
    
    Toxicity Classify 2,3
    
    English Name Acrylamide
    
    Chinese Name 丙烯醯胺
    
    Control concentration standard (w/w%) 30
    
    Large-scale handling standard(kg) 50

Chemical Hazard and Risk Information

GHS Classification Results
- NITE Japan-GHS Data Description
  - Edition version_1
    
    Chemical Substance Name Acrylamide
    
    Classification Result To the resut webpage To the Excel flie
- GHS Classification Results by the Japanese Government Data Description GHS Information
  - Year of implementation /renewal 2006 ID 1_H18_new
    
    Chemical Substance Name Acrylamide
    
    Classification Result To the resut webpage To the Excel flie
    
    Year of implementation /renewal 2017 ID H29-B-011
    
    Chemical Substance Name Acrylamide
    
    Classification Result To the resut webpage To the Excel flie

MHLW:GHS Aligned Sample Label and SDS
- GHS Aligned Sample Label and SDS Data Description Information on GHS Aligned Sample Label and SDS (Workplace Safety Site)
  - Chemical Substance Name Acrylamide
    
    Sample Label to MHLW Website (in Japanese Only)
    
    Sample SDS to MHLW Website (in Japanese Only)

AIST: Relational Information System for Chemical Accidents Database(RISCAD)
- Relational Information System for Chemical Accidents Database(RISCAD) Data Description RISCAD (in Japanese)
  - Material ID 889
    
    Name acrylamide
    
    Material Information to RISCAD

Hazard and Risk Assessment Reports etc. in Japan

Chemical Substances Hazard Assessment Report / Initial Risk Assessment Report Data Description Guidance for Initial Risk Assessment ver.1 (in Japanese) Guidance for Initial Risk Assessment ver.2 (in Japanese)

Report Number	No.35
Assessed Chemical Substance Name	Acrylamide
Details	Hazard Assessment Report (in Japanese)	Date of publication/ renewal	2006/04
	Details Initial Risk Assessment Report (in Japanese)	Date of publication/ renewal	2007/08
	Details Summary of Initial Risk Assessment Report	Date of publication/ renewal	2010/05

ISHA: Examples of Occupational Accidents Caused by Chemical Substances Data Description
- Name Acrylamide
  
  Examples of Occupational Accidents to MHLW site (in Japanese)

Hazard Data Sheet for Chemical Substances Data Description
- Book Number
  96-32
  Date of publication/ renewal 1997/07
  
  Assessed Chemical Substance Name Acrylamide
  
  Details Hazard Data Sheet (in Japanese)

CSCL: The Japan HPV Challenge Program Data Description
- Chemical Substance Name acrylamide
  
  Details to J-CHECK

Hazard and Risk Assessment Reports etc. in Other Countries
- OECD: High Production Volume (HPV) Chemicals Data Description
  - Chemical Name 2-Propenamide
    
    Details to OECD Existing Chemicals Database
- International Chemical Safety Cards (ICSC) Data Description
  - ICSC Number
    91
    
    ICSC Title Acrylamide
    
    Details to ILO site
- Environmental Health Criteria (EHC) Data Description
  - EHC Number
    49
    
    EHC Title Acrylamide
    
    Details to IPCS site
- US Agency for Toxic Substances and Disease Registry (ATSDR): Toxicological Profiles Data Description
  - Profile Title Acrylamide
    
    Details to ATSDR site
    
    Date of Issue December 2012
- US EPA: Integrated Risk Information System (IRIS) Data Description
  - Chemical Substance Name Acrylamide
    
    Details to EPA site Last Revision 2010/03/22
- EU: Risk Assessment Reports (RAR) Data Description
  - EC Number
    201-173-7
    Date 2002/11/29
    
    Report Title acrylamide
    
    Details to ECHA site
- Advisory Committee on Existing Chemicals (BUA) Reports by the German Chemical Society Data Description
  - BUA Number
    103
    
    Substance Name Acrylamide
    
    Related information to BUA site
- Australia: Priority Existing Chemicals (PEC) Assessment Reports Data Description
  - PEC Number
    23
    Date May 2002
    
    Report Title Acrylamide
    
    Details to AICIS site

Japan Society for Occupational Health (JSOH) Recommendation of Occupational Exposure Limits

JSOH: Occupational Exposure Limits Data Description
- Substance Name Acrylamide
  
  Occupational Exposure Limit (ppm) -
  
  Occupational Exposure Limit (mg/m3) 0.1
  
  Details Documentation in Japanese
  
  Year of proposal 2004
  
  Remarks Skin absorption

JSOH: Occupational Carcinogens Data Description

Substance Name	Acrylamide
Carcinogenicity classification	2A
Details	Documentation in Japanese
Year of proposal	1991, 1995, (2004)
Remarks	( ) in the year of proposal indicates year of reconsideration resulting in no classification change.

JSOH: Occupational Sensitizers Data Description
- Substance Name Acrylamide
  
  Airway -
  
  Skin 2
  
  Details Documentation in Japanese
  
  Year of proposal 2013
  
  Remarks -

JSOH: Reproductive Toxicants Data Description
- Substance Name Acrylamide
  
  Reproductive toxicant classification 2
  
  Details Summary
  
  Year of proposal 2014
  
  Remarks -

Carcinogenicity Assessment

IARC: Carcinogenicity Assessment Data Description to IARC site

Volume	60, Sup 7	Volume publication year	1994
Agent Name	Acrylamide
Group	2A
Details	Vol.60 Sup 7 - - -
Additional information	NB Overall evaluation upgraded to Group 2A with supporting evidence from other relevant data

US EPA: Carcinogenicity Assessment Data Description to EPA site
- Chemical Substance Name Acrylamide
  
  Guideline: Category 2005 : L
  
  Exporsure Route Oral route, Inhalation route
  
  Details to Substance Profile

US NTP: Carcinogenicity Assessment Data Description to NTP site
- Chemical Substance Name Acrylamide
  
  Category
  RAHC
  
  NAME OR SYNONYM
  Acrylamide
  
  Details to Substance Profile

European Union (EU): Carcinogenicity Assessment Data Description to ECHA site
- Substance Name acrylamide; prop-2-enamide
  
  Category Code 1B

Safety Summary of Japan(JCIA BIGDr)
- Safety Summary of Japan(JCIA BIGDr) Data Description
  - Substance Name 2-Propenamide
    
    Detail to JCIA BIGDr

Test Data and Reports

Japan METI: Biodegradation and Bioconcentration Results Data Description

Chemical Substance Name	acrylamide
Judgement of Biodegradation	Readily biodegradable	Judgement of Bioconcentration	-
Test result of Bioconcentration	-	Test result of Partition Coefficient	-
Details	to J-CHECK

ISHA: Mutagenicity Test Results for Chemical Substances Data Description to MHLW site (in Japanese)
- Chemical Name Acrylamide
  
  Bacterial Test -
  
  CHL/IU Test Positive

US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts Data Description
- Report Number
  TR-575
  
  Report Title Toxicology and Carcinogenesis Studies of Acrylamide in F344/N Rats and B6C3F1 Mice (Feed and Drinking Water Studies)
  
  Abstract to NTP site Full Text to NTP site

CHRIP_ID	C004-668-13A	CAS RN	79-06-1
Chemical Substance Name	Acrylamide
Molecular Formula	C3H5NO
Molecular Weight	71
SMILES	NC(C=C)=O
Structure

Synonym	Acrylamide
	2-propenamide
	2-Propene amide
	Acrylic acid amide
	Prop-2-enamide
	Vinyl amide

Registration Number	34	Date of Designation	2011/04/01
MITI Number	2-1014
Chemical Substance Name	Acrylamide
Reason for Inclusion	Human Health
Remarks	-
Details	to J-CHECK

Registration Number	1046	Date of Designation in the Official Gazette	2010/04/01
MITI Number	2-1014
Chemical Substance Name	Acrylamide
Remarks	-
Details	to J-CHECK

Cabinet Order Number	Attached table 9-1 of Cabinet order
Cabinet Order Name	Acrylamide
Range of Application for Label (weight%)	>=0.1
Range of Application for SDS (weight%)	>=0.1

GHS Classification Substance Name	Acrylamide
Carcinogenicity in GHS classification	Category 1B	Range of Application (weight%)	>=0.1
Implementation	2023/4/1
Details	to the GHS Classification

Substance Name	Acrylamide
Classification of Target Substances	Special chemical regulations etc.	Cutoff value(weight %)	1
Details	to the GHS Classification

Category	Group-2 substances	Cabinet Order Number	Attached Table 3-2-1 of Cabinet order
Cabinet Order Name	Acrylamide
Range of Application (weight %)	>1
Remarks	Specified Group-2 substances

Registration Number	2
Kinds of substances	Acrylamide
Control Level	0.1mg/m3

Classification	Existing Chemical Substances
Name	Acrylamide
Date of Notification	2004/08/27 Appendix2(1)

UN Number	2074	Class or Division	6.1
Name and Description	ACRYLAMIDE, SOLID
UN packing group	III

UN Number	3426	Class or Division	6.1
Name and Description	ACRYLAMIDE SOLUTION
UN packing group	III

EC Number	201-173-7	Status	Candidate List
Substance Name	Acrylamide
Reason for inclusion	Carcinogenic (Article 57a) / Mutagenic (Article 57b)
Date of inclusion	2010/03/30
Details	to ECHA site

TSCA Chemical Substance Name	2-Propenamide
DEF	-
UVCB	-
FLAG	-
ACTIVITY	ACTIVE

Classification	Deleterious Substances(Cabinet order)	Law or Cabinet Order Number	Article 2-1-1-3 of Cabinet order
Law or Cabinet Order Name	Acrylamide and preparations containing it

Classification	Substances that may be classified as Hazardous Air Pollutants	Cabinet Order Number	2 of Central Environment Council 9th Report (Appendix 1)
Cabinet Order Name	Acrylamide

Classification	Designated Substances	Cabinet Order Number	Article 3-3-9 of Cabinet order
Cabinet Order Name	Acrylamide

EC Number	201-173-7
EC Name	Acrylamide
Description	-
Substance Infocard	Infocard
ECHA Name	-

Number	97-1-171
Category	Toxic Substance(s)
Chemical Substance Name	Acrylamide
Range of Application (%)	>=0.1

Number	06-5-14
Category	Restricted Substance(s)
Chemical Substance Name	Acrylamide
Range of Application (%)	>=0.1

Number	41
Category	Priority Control Substances
Chemical Substance Name	Acrylamide

Number	47
Category	Phase-in substance(s) subject to registration (by June 30, 2018)
Chemical Substance Name	2-Propenamide; Acrylamide
Note	The registration grace period is until June 30, 2018

Listed No./Series No.	50/01
Toxicity Classify	2,3
English Name	Acrylamide
Chinese Name	丙烯醯胺
Control concentration standard (w/w%)	30
Large-scale handling standard(kg)	50

Edition	version_1
Chemical Substance Name	Acrylamide
Classification Result	To the resut webpage To the Excel flie

Year of implementation /renewal	2006	ID	1_H18_new
Chemical Substance Name	Acrylamide
Classification Result	To the resut webpage To the Excel flie

Year of implementation /renewal	2017	ID	H29-B-011
Chemical Substance Name	Acrylamide
Classification Result	To the resut webpage To the Excel flie

Chemical Substance Name	Acrylamide
Sample Label	to MHLW Website (in Japanese Only)
Sample SDS	to MHLW Website (in Japanese Only)

Name	Acrylamide
Examples of Occupational Accidents	to MHLW site (in Japanese)

Book Number	96-32	Date of publication/ renewal	1997/07
Assessed Chemical Substance Name	Acrylamide
Details	Hazard Data Sheet (in Japanese)

Profile Title	Acrylamide
Details	to ATSDR site
Date of Issue	December 2012

EC Number	201-173-7	Date	2002/11/29
Report Title	acrylamide
Details	to ECHA site

BUA Number	103
Substance Name	Acrylamide
Related information	to BUA site

PEC Number	23	Date	May 2002
Report Title	Acrylamide
Details	to AICIS site

Substance Name	Acrylamide
Occupational Exposure Limit (ppm)	-
Occupational Exposure Limit (mg/m3)	0.1
Details	Documentation in Japanese
Year of proposal	2004
Remarks	Skin absorption