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General Information
- General Information
  - General Information Data Description
    - CHRIP_ID C004-679-52A CAS RN 108-24-7
      
      Chemical Substance Name Acetic anhydride
      
      Molecular Formula C4H6O3
      
      Molecular Weight 102
      
      SMILES CC(OC(C)=O)=O
      
      Structure
- Synonym
  - Synonym Data Description
    - Synonym Acetic acid, anhydride
      
      Acetic oxide
      
      Acetyl oxide
      
      Ethanoic anhydride
- Nikkaji
  - Information of Japan Chemical Substance Dictionary (Nikkaji) Data Description
    - Nikkaji Number
      J2.417A
      Detail to J-GLOBAL

Laws and Regulations in Japan

Act on the Evaluation of Chemical Substances and Regulation of Their Manufacture, etc. (Chemical Substances Control Law ; CSCL)

Japan CSCL: Priority Assessment Chemical Substances Data Description Import Clearance Procedures[PDF] Notification of the Manufacturing Amount, etc[PDF]
- Registration Number
  93
  Date of Designation 2012/03/22
  
  MITI Number
  2-690
  
  Chemical Substance Name Acetic anhydride
  
  Reason for Inclusion Human Health
  
  Remarks -
  
  Details to J-CHECK

Japan CSCL: Existing Chemical Substances Data Description Definition of the terms of Section 6 [PDF] Definition of the terms of Section 7 [PDF] Import Clearance Procedures[PDF] Notification of the Manufacturing Amount, etc[PDF]

MITI Number	2-690	Category	Section 2
Chemical Substance Name	Acetic anhydride
Remarks	-
Details	to J-CHECK
Remarks to Existing Chemical Substances of Industrial Safety and Health Act	Chemicals have been notified in accordance with the provisions of Chemical Substances Control Law by June 29, 1979
Details to Existing Chemical Substances of Industrial Safety and Health Act	to MHLW site (in Japanese)

Japan METI: Biodegradation and Bioconcentration Results Data Description

Chemical Substance Name	acetic anhydride
Judgement of Biodegradation	Readily biodegradable	Judgement of Bioconcentration	-
Test result of Bioconcentration	-	Test result of Partition Coefficient	-
Details	to J-CHECK

Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof(PRTR-SDS Law)

Japan: PRTR-SDS Law (from April 2023) Data Description Outline PRTR Law (METI site)

JPSN(Japan PRTR-SDS Number)	736	Classification	I	Cabinet Order Number	1-466
Cabinet Order Name	Acetic anhydride
Remarks	-
Basis of selection	Hazard Data (in Japanese)
Link	- -

Industrial Safety and Health Act (ISHA)
- Japan ISHA: Chemical Substances Requiring Labeling and Delivery of Documents, etc. Data Description GHS compatible model label creation method (MH LW site : in Japanese) Risk assessment implementation support tool (MHLW site : in Japanese)
  - Cabinet Order Number
    Attached table 9-552 of Cabinet order
    
    Cabinet Order Name Acetic anhydride
    
    Range of Application for Label (weight%) >=1
    
    Range of Application for SDS (weight%) >=1
- Japan ISHA: Chemical substances that cause skin disorders, etc. and other chemical substances that must be handled with impermeable protective equipment etc. based on special chemical regulations. Data Description Target substances list(MHLW site: in japanese)
  - Substance Name Acetic anhydride
    
    Classification of Target Substances Skin Irritating Hazardous Substances Cutoff value(weight %) 1
    
    Implementation 2024/4/1
    
    Details to the GHS Classification

Poisonous and Deleterious Substances Control Act

Japan Poisonous and Deleterious Substances Control Act Data Description Link to the Act (MOJ site)

Classification	Deleterious Substances(Cabinet order)	Law or Cabinet Order Number	Article 2-1-98-2 of Cabinet order
Law or Cabinet Order Name	Acetic anhydride and preparations containing it. (except for preparations which contain 0.2% or less of acetic anhydride)

Food Sanitation Act
- Food Sanitation Act: Table 1 (3) in Appended table 1 of Specifications and Standards Notification; Base polymers (Trace amount monomer) Data Description The positive list system for food utensils, containers and packaging (MHLW)
  - Number Name 5. Nonaromatic organic acid; 64)acetic anhydride

Fire Service Act

Fire Service Act : Hazardous Materials Data Description

Number of cabinet order etc.	Article 2, Paragraph 7 of the Act, Appended Table 1, Category IV (4)
Category; Property	Category IV; Inflammable Liquids
Item	Class II petroleums
Property	Non-water soluble liquid
Designated quantity	1,000L
Sources	MHLW Website; Sample SDS

Laws and Regulations in Other countries

Recommendations on the transport of dangerous goods
- Dangerous Goods List (UN Number and Hazard class) Data Description
  - UN Number
    1715
    Class or Division 8
    
    Name and Description ACETIC ANHYDRIDE
    
    Subsidiary hazard 3
    
    UN packing group II

International Convention on the Commodity Description and Coding Systems (HS Convention)

HS Code: Section VI “Products of the Chemical or Allied Industries" Data Description

Chapter	29	Chapter name	Organic chemicals
Heading	2915	Substance name (Heading)	Saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives
HS Code	2915.24	Substance Name	Acetic acid and its salts; acetic anhydride : Acetic anhydride

Association of South-East Asian Nations(ASEAN)
- The ASEAN-Japan Chemical Safety Database (AJCSD).: Laws and Regulations Data Description
  - Detail to AJCSD
- The ASEAN-Japan Chemical Safety Database (AJCSD).: GHS-Related Information Data Description
  - Detail to AJCSD

European Union (EU)

EC Inventory Data Description
- EC Number
  203-564-8
  
  EC Name Acetic anhydride
  
  Description -
  
  Substance Infocard Infocard
  
  ECHA Name -

EU: CLP Harmonised Classification Data Description To ECHA site

Index Number	607-008-00-9	EC Number	203-564-8
Chemical Name	acetic anhydride
Classification	Flam. Liq. 3 / [Inh.]Acute Tox. 4 * / [Oral]Acute Tox. 4 * / Skin Corr. 1B
Specific Conc. Limits, M-factors	Skin Corr. 1B; H314: C ≥ 25 % / Skin Irrit. 2; H315: 5 % ≤ C < 25 % / Eye Dam. 1; H318: 5 % ≤ C < 25 % / Eye Irrit. 2; H319: 1 % ≤ C < 5 % / STOT SE 3; H335: C ≥ 5 %

US: Toxic Substances Control Act (TSCA)
- TSCA Inventory Data Description
  - TSCA Chemical Substance Name Acetic acid, 1,1'-anhydride
    
    DEF -
    
    UVCB -
    
    FLAG -
    
    ACTIVITY ACTIVE

China
- China: Catalog of Hazardous Chemicals 2015 Data Description
  - Number
    2634
    
    Name Ethanoic anhydride
    
    Other Name Acetic anhydride
    
    Remarks -

Korea

Korea: ARECs (K-REACH); Existing Chemical Substances Data Description

KE Number	KE-00017
Category	Existing Chemical Substances (Domestically distributed commercial purpose before February 2, 1991.)
Chemical Substance Name	Acetic anhydride
Remarks	In the case of being hydrated, the resulting hydrate is also applicable.

Taiwan
- Taiwan: TCCSCA/OSHA; Existing Chemical Substances Data Description
  - English Name acetic anhydride
    
    Chinese Name -

Chemical Hazard and Risk Information

GHS Classification Results

NITE Japan-GHS Data Description
- Edition version_1
  
  Chemical Substance Name Acetic anhydride
  
  Classification Result To the resut webpage To the Excel flie

GHS Classification Results by the Japanese Government Data Description GHS Information

Year of implementation /renewal	2006	ID	965_H18_new
Chemical Substance Name	Acetic anhydride
Classification Result	To the resut webpage To the Excel flie

Year of implementation /renewal	2018	ID	H30-C-029-MOE
Chemical Substance Name	Acetic anhydride
Classification Result	To the resut webpage To the Excel flie

Year of implementation /renewal	2019	ID	R01-B-021
Chemical Substance Name	Acetic anhydride
Classification Result	To the resut webpage To the Excel flie
Remarks	The reclassification result of only physical and health hazard classes. As for environmental hazard classes, please see the result in FY2018.

MHLW:GHS Aligned Sample Label and SDS
- GHS Aligned Sample Label and SDS Data Description Information on GHS Aligned Sample Label and SDS (Workplace Safety Site)
  - Chemical Substance Name Acetic anhydride
    
    Sample Label to MHLW Website (in Japanese Only)
    
    Sample SDS to MHLW Website (in Japanese Only)

AIST: Relational Information System for Chemical Accidents Database(RISCAD)
- Relational Information System for Chemical Accidents Database(RISCAD) Data Description RISCAD (in Japanese)
  - Material ID 1119
    
    Name acetic anhydride
    
    Material Information to RISCAD
    
    Accident Information to RISCAD

Hazard and Risk Assessment Reports etc. in Japan
- ISHA: Examples of Occupational Accidents Caused by Chemical Substances Data Description
  - Name Acetic anhydride
    
    Examples of Occupational Accidents to MHLW site (in Japanese)
- Hazard Data Sheet for Chemical Substances Data Description
  - Book Number
    2000-1
    Date of publication/ renewal 2001/09
    
    Assessed Chemical Substance Name Acetic anhydride
    
    Details Hazard Data Sheet (in Japanese)
- CSCL: The Japan HPV Challenge Program Data Description
  - Chemical Substance Name acetic anhydride
    
    Details to J-CHECK

Hazard and Risk Assessment Reports etc. in Other Countries
- OECD: High Production Volume (HPV) Chemicals Data Description
  - Chemical Name Acetic anhydride
    
    Details to OECD Existing Chemicals Database
- International Chemical Safety Cards (ICSC) Data Description
  - ICSC Number
    209
    
    ICSC Title Acetic anhydride
    
    Details to ILO site
- Advisory Committee on Existing Chemicals (BUA) Reports by the German Chemical Society Data Description
  - BUA Number
    70
    
    Substance Name Acetic anhydride
    
    Related information to BUA site

Japan Society for Occupational Health (JSOH) Recommendation of Occupational Exposure Limits

JSOH: Occupational Exposure Limits Data Description

Substance Name	Acetic anhydride
Occupational Exposure Limit (ppm)	5 (Occupational Exposure Limit-Ceiling)
Occupational Exposure Limit (mg/m3)	21 (Occupational Exposure Limit-Ceiling)
Details	Documentation in Japanese
Year of proposal	1990
Remarks	-

Safety Summary of Japan(JCIA BIGDr)
- Safety Summary of Japan(JCIA BIGDr) Data Description
  - Substance Name Acetic acid, 1,1'-anhydride
    
    Detail to JCIA BIGDr

Test Data and Reports

Japan METI: Biodegradation and Bioconcentration Results Data Description

Chemical Substance Name	acetic anhydride
Judgement of Biodegradation	Readily biodegradable	Judgement of Bioconcentration	-
Test result of Bioconcentration	-	Test result of Partition Coefficient	-
Details	to J-CHECK

ISHA: Mutagenicity Test Results for Chemical Substances Data Description to MHLW site (in Japanese)
- Chemical Name Aceticanhydride
  
  Bacterial Test Negative
  
  CHL/IU Test -

CHRIP_ID	C004-679-52A	CAS RN	108-24-7
Chemical Substance Name	Acetic anhydride
Molecular Formula	C4H6O3
Molecular Weight	102
SMILES	CC(OC(C)=O)=O
Structure

Synonym	Acetic acid, anhydride
	Acetic oxide
	Acetyl oxide
	Ethanoic anhydride

Registration Number	93	Date of Designation	2012/03/22
MITI Number	2-690
Chemical Substance Name	Acetic anhydride
Reason for Inclusion	Human Health
Remarks	-
Details	to J-CHECK

Cabinet Order Number	Attached table 9-552 of Cabinet order
Cabinet Order Name	Acetic anhydride
Range of Application for Label (weight%)	>=1
Range of Application for SDS (weight%)	>=1

Substance Name	Acetic anhydride
Classification of Target Substances	Skin Irritating Hazardous Substances	Cutoff value(weight %)	1
Implementation	2024/4/1
Details	to the GHS Classification

UN Number	1715	Class or Division	8
Name and Description	ACETIC ANHYDRIDE
Subsidiary hazard	3
UN packing group	II

EC Number	203-564-8
EC Name	Acetic anhydride
Description	-
Substance Infocard	Infocard
ECHA Name	-

TSCA Chemical Substance Name	Acetic acid, 1,1'-anhydride
DEF	-
UVCB	-
FLAG	-
ACTIVITY	ACTIVE

Number	2634
Name	Ethanoic anhydride
Other Name	Acetic anhydride
Remarks	-

Edition	version_1
Chemical Substance Name	Acetic anhydride
Classification Result	To the resut webpage To the Excel flie

Material ID	1119
Name	acetic anhydride
Material Information	to RISCAD
Accident Information	to RISCAD

ICSC Number	209
ICSC Title	Acetic anhydride
Details	to ILO site

Chemical Substance Name	Acetic anhydride
Sample Label	to MHLW Website (in Japanese Only)
Sample SDS	to MHLW Website (in Japanese Only)

Name	Acetic anhydride
Examples of Occupational Accidents	to MHLW site (in Japanese)

Book Number	2000-1	Date of publication/ renewal	2001/09
Assessed Chemical Substance Name	Acetic anhydride
Details	Hazard Data Sheet (in Japanese)

BUA Number	70
Substance Name	Acetic anhydride
Related information	to BUA site

Substance Name	Acetic acid, 1,1'-anhydride
Detail	to JCIA BIGDr

Chemical Name	Aceticanhydride
Bacterial Test	Negative
CHL/IU Test	-