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General Information
- General Information
  - General Information Data Description
    - CHRIP_ID C004-737-38A CAS RN 100-00-5
      
      Chemical Substance Name p-Nitrochlorobenzene
      
      Molecular Formula C6H4ClNO2
      
      Molecular Weight 158
      
      SMILES O=[N+]([O-])C1=CC=C(Cl)C=C1
      
      Structure
- Synonym
  - Synonym Data Description
    - Synonym p-Chloronitrobenzene
      
      1-Chloro-4-nitrobenzene
      
      Benzene, 1-chloro-4-nitro-
      
      Chloronitrobenzenes
      
      p-Chloronitrobenzene
      
      PCNB
      
      PNCB
- Nikkaji
  - Information of Japan Chemical Substance Dictionary (Nikkaji) Data Description
    - Nikkaji Number
      J3.586F
      Detail to J-GLOBAL

Laws and Regulations in Japan

Act on the Evaluation of Chemical Substances and Regulation of Their Manufacture, etc. (Chemical Substances Control Law ; CSCL)

Japan CSCL: Priority Assessment Chemical Substances Data Description Import Clearance Procedures[PDF] Notification of the Manufacturing Amount, etc[PDF]
- Registration Number
  60
  Date of Designation 2011/04/01
  
  MITI Number
  3-442
  
  Chemical Substance Name p-Chloronitrobenzene
  
  Reason for Inclusion Human Health
  
  Remarks -
  
  Details to J-CHECK

Japan CSCL: Existing Chemical Substances Data Description Definition of the terms of Section 6 [PDF] Definition of the terms of Section 7 [PDF] Import Clearance Procedures[PDF] Notification of the Manufacturing Amount, etc[PDF]

MITI Number	3-442	Category	Section 3
Chemical Substance Name	Monochloro-nitrobenzene
Remarks	-
Details	to J-CHECK
Remarks to Existing Chemical Substances of Industrial Safety and Health Act	Chemicals have been notified in accordance with the provisions of Chemical Substances Control Law by June 29, 1979
Details to Existing Chemical Substances of Industrial Safety and Health Act	to MHLW site (in Japanese)

Japan CSCL: Type II Monitoring Chemical Substances (before amendment) Data Description Import Clearance Procedures[PDF] Notification of the Manufacturing Amount, etc[PDF]
- Registration Number
  410
  Date of Designation in the Official Gazette 2000/09/22
  
  MITI Number
  3-442
  
  Chemical Substance Name p-Chloronitrobenzene
  
  Remarks -
  
  Details to J-CHECK

Japan METI: Biodegradation and Bioconcentration Results Data Description

Chemical Substance Name	p-chloronitrobenzene
Judgement of Biodegradation	Not readily biodegradable	Judgement of Bioconcentration	Low bioconcentration
Test result of Bioconcentration	-	Test result of Partition Coefficient	-
Details	to J-CHECK

Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof(PRTR-SDS Law)

Japan: PRTR-SDS Law (until March 2023) Data Description Outline PRTR Law (METI site) Analysis of PRTR data

Classification	I	Cabinet Order Number	1-314
Cabinet Order Name	p-Nitrochlorobenzene
Remarks	-
Basis of selection	Hazard Data (in Japanese)
Link	Releases Map (in Japanese) Atmospheric concentration Map (in Japanese)

Japan: PRTR-SDS Law (from April 2023) Data Description Outline PRTR Law (METI site)

JPSN(Japan PRTR-SDS Number)	314	Classification	I	Cabinet Order Number	1-358
Cabinet Order Name	p-Nitrochlorobenzene
Remarks	-
Basis of selection	Hazard Data (in Japanese)
Link	- -

Industrial Safety and Health Act (ISHA)

Japan ISHA: Chemical Substances Requiring Labeling and Delivery of Documents, etc. Data Description GHS compatible model label creation method (MH LW site : in Japanese) Risk assessment implementation support tool (MHLW site : in Japanese)
- Cabinet Order Number
  Attached table 9-445 of Cabinet order
  
  Cabinet Order Name p-Nitrochlorobenzene
  
  Range of Application for Label (weight%) >=1
  
  Range of Application for SDS (weight%) >=0.1

Japan ISHA: Chemical substances that cause skin disorders, etc. and other chemical substances that must be handled with impermeable protective equipment etc. based on special chemical regulations. Data Description Target substances list(MHLW site: in japanese)
- Substance Name p-Nitrochlorobenzene
  
  Classification of Target Substances Special chemical regulations etc. Cutoff value(weight %) 5
  
  Details to the GHS Classification

Japan ISHA: Specified Chemical Substances Data Description Link to the Ordinance (JISHA site : in Japanese)

Category	Group-2 substances	Cabinet Order Number	Attached Table 3-2-27 of Cabinet order
Cabinet Order Name	p-Nitrochlorobenzene
Range of Application (weight %)	>5
Remarks	Specified Group-2 substances

The above information have been provided by the Ministry of Health, Labour and Welfare

Japan ISHA: Administrative Control Levels of Working Environment Evaluation Standards Data Description Working Environment Measurement (MHLW site : in Japanese)
- Registration Number
  24
  
  Kinds of substances p-nitrochlorobenzene
  
  Control Level 0.6mg/m3
  
  The above information have been provided by the Ministry of Health, Labour and Welfare

Japan ISHA: Guidelines for Carcinogenic Substances Data Description
- Name p-Nitrochlorobenzene
  
  Details to MHLW site (in Japanese)

Japan ISHA: Strong Mutagenic Chemical Substances Data Description Related information (MHLW site : in Japanese)
- Classification Existing Chemical Substances
  
  Name p-Chloronitrobenzene
  
  Date of Notification 1993/05/17 Appendix2(2-14)

Poisonous and Deleterious Substances Control Act
- Japan Poisonous and Deleterious Substances Control Act Data Description Link to the Act (MOJ site)
  - Classification Deleterious Substances(Cabinet order) Law or Cabinet Order Number
    Article 2-1-28-9 of Cabinet order
    
    Law or Cabinet Order Name 1-Chloro-4-nitrobenzene and preparations containing it

Air Pollution Control Act

Japan Air Pollution Control Law Data Description Air & Transportation (MOE site)

Classification	Substances that may be classified as Hazardous Air Pollutants	Cabinet Order Number	54 of Central Environment Council 9th Report (Appendix 1)
Cabinet Order Name	p-Chloronitrobenzene; p-Nitrochlorobenzene

Laws and Regulations in Other countries

Recommendations on the transport of dangerous goods
- Dangerous Goods List (UN Number and Hazard class) Data Description
  - UN Number
    1578
    Class or Division 6.1
    
    Name and Description CHLORONITROBENZENES, SOLID
    
    UN packing group II
    
    UN Number
    3409
    Class or Division 6.1
    
    Name and Description CHLORONITROBENZENES, LIQUID
    
    UN packing group II

Association of South-East Asian Nations(ASEAN)
- The ASEAN-Japan Chemical Safety Database (AJCSD).: Laws and Regulations Data Description
  - Detail to AJCSD

European Union (EU)

EC Inventory Data Description
- EC Number
  202-809-6
  
  EC Name 1-chloro-4-nitrobenzene
  
  Description -
  
  Substance Infocard Infocard
  
  ECHA Name -

EU: CLP Harmonised Classification Data Description To ECHA site

Index Number	610-005-00-5	EC Number	202-809-6
Chemical Name	1-chloro-4-nitrobenzene
Classification	Carc. 2 / Muta. 2 / [Inh.]Acute Tox. 3 * / [Der.]Acute Tox. 3 * / [Oral]Acute Tox. 3 * / STOT RE 2 * / Aquatic Chronic 2

US: Toxic Substances Control Act (TSCA)
- TSCA Inventory Data Description
  - TSCA Chemical Substance Name Benzene, 1-chloro-4-nitro-
    
    DEF -
    
    UVCB -
    
    FLAG -
    
    ACTIVITY ACTIVE

China
- China: Catalog of Hazardous Chemicals 2015 Data Description
  - Number
    1546
    
    Name 4-Chloronitrobenzene
    
    Other Name p-Chloronitrobenzene;1-Chloro-4-nitrobenzene
    
    Remarks -

Korea

Korea: ARECs (K-REACH); Existing Chemical Substances Data Description

KE Number	KE-05780
Category	Existing Chemical Substances (Domestically distributed commercial purpose before February 2, 1991.)
Chemical Substance Name	1-Chloro-4-nitrobenzene ; p-Nitrochlorobenzene, p-Chloronitrobenzene
Remarks	In the case of being hydrated, the resulting hydrate is also applicable.

Taiwan
- Taiwan: TCCSCA/OSHA; Existing Chemical Substances Data Description
  - English Name p-Nitrochlorobenzene
    
    Chinese Name -

Chemical Hazard and Risk Information

GHS Classification Results

NITE Japan-GHS Data Description
- Edition version_2
  
  Chemical Substance Name p-Nitrochlorobenzene
  
  Classification Result To the resut webpage To the Excel flie

GHS Classification Results by the Japanese Government Data Description GHS Information

Year of implementation /renewal	2006	ID	174_H18_new
Chemical Substance Name	p-Nitrochlorobenzene
Classification Result	To the resut webpage To the Excel flie

Year of implementation /renewal	2009	ID	21B3162
Chemical Substance Name	p-Nitrochlorobenzene
Classification Result	To the resut webpage To the Excel flie

Year of implementation /renewal	2021	ID	R03-B-013-MHLW
Chemical Substance Name	p-Nitrochlorobenzene
Classification Result	To the resut webpage To the Excel flie
Remarks	The reclassification result of only physical and health hazard classes. As for environmental hazard classes, please see the result in FY2009.

MHLW:GHS Aligned Sample Label and SDS
- GHS Aligned Sample Label and SDS Data Description Information on GHS Aligned Sample Label and SDS (Workplace Safety Site)
  - Chemical Substance Name p-Nitrochlorobenzene
    
    Sample Label to MHLW Website (in Japanese Only)
    
    Sample SDS to MHLW Website (in Japanese Only)

AIST: Relational Information System for Chemical Accidents Database(RISCAD)
- Relational Information System for Chemical Accidents Database(RISCAD) Data Description RISCAD (in Japanese)
  - Material ID 1534
    
    Name 4-chloronitrobenzene
    
    Material Information to RISCAD
    
    Accident Information to RISCAD

Hazard and Risk Assessment Reports etc. in Japan

Chemical Substances Hazard Assessment Report / Initial Risk Assessment Report Data Description Guidance for Initial Risk Assessment ver.1 (in Japanese) Guidance for Initial Risk Assessment ver.2 (in Japanese)

Report Number	No.57
Assessed Chemical Substance Name	p-Nitrochlorobenzene
Details	Hazard Assessment Report (in Japanese)	Date of publication/ renewal	2008/02
	Details Initial Risk Assessment Report (in Japanese)	Date of publication/ renewal	2005/05
	Details Summary of Initial Risk Assessment Report	Date of publication/ renewal	2010/05

Hazard Data Sheet for Chemical Substances Data Description
- Book Number
  96-36
  Date of publication/ renewal 1997/07
  
  Assessed Chemical Substance Name p-Chloronitrobenzene
  
  Details Hazard Data Sheet (in Japanese)

CSCL: The Japan HPV Challenge Program Data Description
- Chemical Substance Name p-Chloronitrobenzene
  
  Details to J-CHECK

Hazard and Risk Assessment Reports etc. in Other Countries
- OECD: High Production Volume (HPV) Chemicals Data Description
  - Chemical Name Benzene, 1-chloro-4-nitro-
    
    Details to OECD Existing Chemicals Database
- International Chemical Safety Cards (ICSC) Data Description
  - ICSC Number
    846
    
    ICSC Title p-Nitrochlorobenzene
    
    Details to ILO site
- Advisory Committee on Existing Chemicals (BUA) Reports by the German Chemical Society Data Description
  - BUA Number
    11, 114, 259
    
    Substance Name p-Chloronitrobenzene
    
    Related information to BUA site

Japan Society for Occupational Health (JSOH) Recommendation of Occupational Exposure Limits

JSOH: Occupational Exposure Limits Data Description

Substance Name	p-Nitrochlorobenzene
Occupational Exposure Limit (ppm)	0.1
Occupational Exposure Limit (mg/m3)	0.64
Details	Documentation in Japanese
Year of proposal	1989
Remarks	Skin absorption

JSOH: Occupational Carcinogens Data Description
- Substance Name p-Nitrochlorobenzene
  
  Carcinogenicity classification 2B
  
  Details -
  
  Year of proposal 2019
  
  Remarks -

Carcinogenicity Assessment

IARC: Carcinogenicity Assessment Data Description to IARC site

Volume	65, 123	Volume publication year	2020 online
Agent Name	4-Chloronitrobenzene
Group	2B
Details	Vol.65 Vol.123 - - -

Volume	-	Volume publication year	-
Agent Name	Chloronitrobenzenes (see 2-Chloronitrobenzene, 3-Chloronitrobenzene, 4-Chloronitrobenzene)
Group	-
Details	- - - - -

European Union (EU): Carcinogenicity Assessment Data Description to ECHA site
- Substance Name 1-chloro-4-nitrobenzene
  
  Category Code 2

Test Data and Reports

Japan METI: Biodegradation and Bioconcentration Results Data Description

Chemical Substance Name	p-chloronitrobenzene
Judgement of Biodegradation	Not readily biodegradable	Judgement of Bioconcentration	Low bioconcentration
Test result of Bioconcentration	-	Test result of Partition Coefficient	-
Details	to J-CHECK

ISHA: Carcinogenicity Test Results for Chemical Substances Data Description to MHLW site (in Japanese)
- Chemical Name p-Nitrochlorobenzene
  
  Summary Oral test results (in Japanese)

ISHA: Mutagenicity Test Results for Chemical Substances Data Description to MHLW site (in Japanese)
- Chemical Name p-Chloronitrobenzene
  
  Bacterial Test Positive
  
  CHL/IU Test Positive

CHRIP_ID	C004-737-38A	CAS RN	100-00-5
Chemical Substance Name	p-Nitrochlorobenzene
Molecular Formula	C6H4ClNO2
Molecular Weight	158
SMILES	O=[N+]([O-])C1=CC=C(Cl)C=C1
Structure

Synonym	p-Chloronitrobenzene
	1-Chloro-4-nitrobenzene
	Benzene, 1-chloro-4-nitro-
	Chloronitrobenzenes
	p-Chloronitrobenzene
	PCNB
	PNCB

Registration Number	60	Date of Designation	2011/04/01
MITI Number	3-442
Chemical Substance Name	p-Chloronitrobenzene
Reason for Inclusion	Human Health
Remarks	-
Details	to J-CHECK

Registration Number	410	Date of Designation in the Official Gazette	2000/09/22
MITI Number	3-442
Chemical Substance Name	p-Chloronitrobenzene
Remarks	-
Details	to J-CHECK

Cabinet Order Number	Attached table 9-445 of Cabinet order
Cabinet Order Name	p-Nitrochlorobenzene
Range of Application for Label (weight%)	>=1
Range of Application for SDS (weight%)	>=0.1

Substance Name	p-Nitrochlorobenzene
Classification of Target Substances	Special chemical regulations etc.	Cutoff value(weight %)	5
Details	to the GHS Classification

Registration Number	24
Kinds of substances	p-nitrochlorobenzene
Control Level	0.6mg/m3

Classification	Existing Chemical Substances
Name	p-Chloronitrobenzene
Date of Notification	1993/05/17 Appendix2(2-14)

Classification	Deleterious Substances(Cabinet order)	Law or Cabinet Order Number	Article 2-1-28-9 of Cabinet order
Law or Cabinet Order Name	1-Chloro-4-nitrobenzene and preparations containing it

UN Number	1578	Class or Division	6.1
Name and Description	CHLORONITROBENZENES, SOLID
UN packing group	II

TSCA Chemical Substance Name	Benzene, 1-chloro-4-nitro-
DEF	-
UVCB	-
FLAG	-
ACTIVITY	ACTIVE

Material ID	1534
Name	4-chloronitrobenzene
Material Information	to RISCAD
Accident Information	to RISCAD

UN Number	3409	Class or Division	6.1
Name and Description	CHLORONITROBENZENES, LIQUID
UN packing group	II

EC Number	202-809-6
EC Name	1-chloro-4-nitrobenzene
Description	-
Substance Infocard	Infocard
ECHA Name	-

Number	1546
Name	4-Chloronitrobenzene
Other Name	p-Chloronitrobenzene;1-Chloro-4-nitrobenzene
Remarks	-

Edition	version_2
Chemical Substance Name	p-Nitrochlorobenzene
Classification Result	To the resut webpage To the Excel flie

Chemical Substance Name	p-Nitrochlorobenzene
Sample Label	to MHLW Website (in Japanese Only)
Sample SDS	to MHLW Website (in Japanese Only)

Book Number	96-36	Date of publication/ renewal	1997/07
Assessed Chemical Substance Name	p-Chloronitrobenzene
Details	Hazard Data Sheet (in Japanese)

ICSC Number	846
ICSC Title	p-Nitrochlorobenzene
Details	to ILO site

BUA Number	11, 114, 259
Substance Name	p-Chloronitrobenzene
Related information	to BUA site

Substance Name	p-Nitrochlorobenzene
Carcinogenicity classification	2B
Details	-
Year of proposal	2019
Remarks	-

Chemical Name	p-Nitrochlorobenzene
Summary	Oral test results (in Japanese)

Chemical Name	p-Chloronitrobenzene
Bacterial Test	Positive
CHL/IU Test	Positive