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General Information
- General Information
  - General Information Data Description
    - CHRIP_ID C004-993-81A CAS RN 100-17-4
      
      Chemical Substance Name p-Methoxynitrobenzene
      
      Molecular Formula C7H7NO3
      
      Molecular Weight 153
      
      SMILES O=[N+]([O-])C1=CC=C(OC)C=C1
      
      Structure
- Synonym
  - Synonym Data Description
    - Synonym p-Methoxynitrobenzene
      
      4-nitrophenyl methyl ether
- Nikkaji
  - Information of Japan Chemical Substance Dictionary (Nikkaji) Data Description
    - Nikkaji Number
      J4.003G
      Detail to J-GLOBAL

Laws and Regulations in Japan

Act on the Evaluation of Chemical Substances and Regulation of Their Manufacture, etc. (Chemical Substances Control Law ; CSCL)

Japan CSCL: Existing Chemical Substances Data Description Definition of the terms of Section 6 [PDF] Definition of the terms of Section 7 [PDF] Import Clearance Procedures[PDF] Notification of the Manufacturing Amount, etc[PDF]

MITI Number	3-787	Category	Section 3
Chemical Substance Name	Nitro-methoxybenzene
Remarks	-
Details	to J-CHECK
Remarks to Existing Chemical Substances of Industrial Safety and Health Act	Chemicals have been notified in accordance with the provisions of Chemical Substances Control Law by June 29, 1979
Details to Existing Chemical Substances of Industrial Safety and Health Act	to MHLW site (in Japanese)

Japan METI: Biodegradation and Bioconcentration Results Data Description

Chemical Substance Name	4-nitrophenyl methyl ether
Judgement of Biodegradation	Not readily biodegradable	Judgement of Bioconcentration	Low bioconcentration
Test result of Bioconcentration	-	Test result of Partition Coefficient	-
Details	to J-CHECK

Industrial Safety and Health Act (ISHA)

Japan ISHA: Chemical Substances Requiring Labeling and Delivery of Documents, etc. Data Description GHS compatible model label creation method (MH LW site : in Japanese) Risk assessment implementation support tool (MHLW site : in Japanese)

Cabinet Order Number	Attached table 9-447-2 of Cabinet order: To be enforced from April 1, 2024
Cabinet Order Name	p-Methoxynitrobenzene
Range of Application for Label (weight%)	>=0.1
Range of Application for SDS (weight%)	>=0.1

Japan ISHA: Carcinogenic Substances (Ordinance on Industrial Safety and Health) (subject to 30-year storage of work records, etc.) Data Description Lists of Target Substances (MHLW site : in Japanese)

GHS Classification Substance Name	p-Methoxynitrobenzene (synonym: p-nitroanisole)
Carcinogenicity in GHS classification	Category 1B	Range of Application (weight%)	>=0.1
Implementation	2024/4/1
Details	to the GHS Classification

Japan ISHA: Guidelines for Carcinogenic Substances Data Description
- Name p-Nitroanisole
  
  Details to MHLW site (in Japanese)

Japan ISHA: Strong Mutagenic Chemical Substances Data Description Related information (MHLW site : in Japanese)
- Classification Existing Chemical Substances
  
  Name p-Methoxynitrobenzene
  
  Date of Notification 1997/01/06 Appendix2(8)

Laws and Regulations in Other countries

Association of South-East Asian Nations(ASEAN)
- The ASEAN-Japan Chemical Safety Database (AJCSD).: Laws and Regulations Data Description
  - Detail to AJCSD

European Union (EU)
- EC Inventory Data Description
  - EC Number
    202-825-3
    
    EC Name 4-nitroanisole
    
    Description -
    
    Substance Infocard Infocard
    
    ECHA Name -

US: Toxic Substances Control Act (TSCA)
- TSCA Inventory Data Description
  - TSCA Chemical Substance Name Benzene, 1-methoxy-4-nitro-
    
    DEF -
    
    UVCB -
    
    FLAG -
    
    ACTIVITY ACTIVE

China
- China: Catalog of Hazardous Chemicals 2015 Data Description
  - Number
    2241
    
    Name 4-Nitrophenyl methyl ether
    
    Other Name p-Nitrophenyl methyl ether; p-Nitroanisole; p-Methoxynitrobenzene
    
    Remarks -

Korea

Korea: ARECs (K-REACH); Existing Chemical Substances Data Description

KE Number	KE-23338
Category	Existing Chemical Substances (Domestically distributed commercial purpose before February 2, 1991.)
Chemical Substance Name	p-Nitroanisole
Remarks	In the case of being hydrated, the resulting hydrate is also applicable.

Taiwan
- Taiwan: TCCSCA/OSHA; Existing Chemical Substances Data Description
  - English Name 4-nitroanisole
    
    Chinese Name -

Chemical Hazard and Risk Information

GHS Classification Results

NITE Japan-GHS Data Description
- Edition version_2
  
  Chemical Substance Name p-Methoxynitrobenzene
  
  Classification Result To the resut webpage To the Excel flie

GHS Classification Results by the Japanese Government Data Description GHS Information

Year of implementation /renewal	2009	ID	21A3524
Chemical Substance Name	p-Methoxynitrobenzene
Classification Result	To the resut webpage To the Excel flie

Year of implementation /renewal	2018	ID	H30-C-008-MHLW
Chemical Substance Name	p-Methoxynitrobenzene
Classification Result	To the resut webpage To the Excel flie
Remarks	The reclassification result of only some hazard classes. As for the other classes, please see the result in FY2009.

Year of implementation /renewal	2021	ID	R03-C-007-MHLW
Chemical Substance Name	p-Methoxynitrobenzene (synonym: p-Nitroanisole)
Classification Result	To the resut webpage To the Excel flie
Remarks	The reclassification result of only some hazard classes. As for the other classes, please see the result in FY2009.

MHLW:GHS Aligned Sample Label and SDS
- GHS Aligned Sample Label and SDS Data Description Information on GHS Aligned Sample Label and SDS (Workplace Safety Site)
  - Chemical Substance Name p-Methoxynitrobenzene (synonym: p-Nitroanisole)
    
    Sample Label to MHLW Website (in Japanese Only)
    
    Sample SDS to MHLW Website (in Japanese Only)

AIST: Relational Information System for Chemical Accidents Database(RISCAD)
- Relational Information System for Chemical Accidents Database(RISCAD) Data Description RISCAD (in Japanese)
  - Material ID 5161
    
    Name p-nitroanisole
    
    Material Information to RISCAD

Hazard and Risk Assessment Reports etc. in Other Countries
- Advisory Committee on Existing Chemicals (BUA) Reports by the German Chemical Society Data Description
  - BUA Number
    10, 114
    
    Substance Name p-Nitroanisole
    
    Related information to BUA site

Japan Society for Occupational Health (JSOH) Recommendation of Occupational Exposure Limits
- JSOH: Occupational Carcinogens Data Description
  - Substance Name 4-Nitroanisole
    
    Carcinogenicity classification 2B
    
    Details -
    
    Year of proposal 2019
    
    Remarks -

Carcinogenicity Assessment
- IARC: Carcinogenicity Assessment Data Description to IARC site
  - Volume 123 Volume publication year 2020 online
    
    Agent Name para-Nitroanisole
    
    Group 2B
    
    Details Vol.123 - - - -

Test Data and Reports

Japan METI: Biodegradation and Bioconcentration Results Data Description

Chemical Substance Name	4-nitrophenyl methyl ether
Judgement of Biodegradation	Not readily biodegradable	Judgement of Bioconcentration	Low bioconcentration
Test result of Bioconcentration	-	Test result of Partition Coefficient	-
Details	to J-CHECK

ISHA: Carcinogenicity Test Results for Chemical Substances Data Description to MHLW site (in Japanese)
- Chemical Name p-Methoxynitrobenzene
  
  Summary Oral test results (in Japanese)

ISHA: Mutagenicity Test Results for Chemical Substances Data Description to MHLW site (in Japanese)
- Chemical Name p-Nitroanisole(p-Methoxynitrobenzene)
  
  Bacterial Test Positive
  
  CHL/IU Test Positive

CHRIP_ID	C004-993-81A	CAS RN	100-17-4
Chemical Substance Name	p-Methoxynitrobenzene
Molecular Formula	C7H7NO3
Molecular Weight	153
SMILES	O=[N+]([O-])C1=CC=C(OC)C=C1
Structure

Classification	Existing Chemical Substances
Name	p-Methoxynitrobenzene
Date of Notification	1997/01/06 Appendix2(8)

EC Number	202-825-3
EC Name	4-nitroanisole
Description	-
Substance Infocard	Infocard
ECHA Name	-

TSCA Chemical Substance Name	Benzene, 1-methoxy-4-nitro-
DEF	-
UVCB	-
FLAG	-
ACTIVITY	ACTIVE

Number	2241
Name	4-Nitrophenyl methyl ether
Other Name	p-Nitrophenyl methyl ether; p-Nitroanisole; p-Methoxynitrobenzene
Remarks	-

Edition	version_2
Chemical Substance Name	p-Methoxynitrobenzene
Classification Result	To the resut webpage To the Excel flie

Chemical Substance Name	p-Methoxynitrobenzene (synonym: p-Nitroanisole)
Sample Label	to MHLW Website (in Japanese Only)
Sample SDS	to MHLW Website (in Japanese Only)

Material ID	5161
Name	p-nitroanisole
Material Information	to RISCAD

BUA Number	10, 114
Substance Name	p-Nitroanisole
Related information	to BUA site

Substance Name	4-Nitroanisole
Carcinogenicity classification	2B
Details	-
Year of proposal	2019
Remarks	-

Volume	123	Volume publication year	2020 online
Agent Name	para-Nitroanisole
Group	2B
Details	Vol.123 - - - -

Chemical Name	p-Nitroanisole(p-Methoxynitrobenzene)
Bacterial Test	Positive
CHL/IU Test	Positive

Chemical Name	p-Methoxynitrobenzene
Summary	Oral test results (in Japanese)