National Institute of Technology and Evaluation
Collecting and transmitting information required for total risk assessment and management of chemical substance mark NITE TOP> Chemical Management Field> NITE-CHRIP
 

NITE-CHRIP is a database provided information on Risk Assessments

and Laws & Regulations, etc., of chemical substances.

Update history (to NITE-CHRIP Top)
March 12, 2024

Following information has been added newly.
  1. Notes on CAS RN
Following data have been updated.
  1. Japan CSCL: Class I Specified Chemical Substances
      1 substance (PFHxS or its isomers or their salts) has been added based on the notifications of December 1, 2023.
    Confirmed link of CAS RN: 39 links (PFHxS or its isomers or their salts: 37 links, PFOS or its salts: 2 links)have been added.
  2. Japan CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 1 link has been added.
  3. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 5 links have been added.
  4. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 11 links have been added.
  5. Japan ISHA: Newly Announced Chemical Substances
      210 substances (December 27, 2023 public notice) have been added.
  6. Japan: Air Pollution Control Law
      22 substances have been added and 2 substances have been deleted by reviewing the data.
  7. Japan: Water Pollution Prevention Act
      In accordance with the amendment promulgated on January 25, 2024 ,the effluent standards for 75 substances have been changed.
  8. REACH: Substances of Very High Concern for Authorization (SVHC)
      11 substances have been added for Candidate List, reflecting the data published on January 23, 2024.
  9. TSCA Inventory
      907 substances have been added, 11 substance names have been changed and ""ACTIVE"" information has been changed to 19 substances based on the list updated on February 2024.
  10. TSCA: Significant New Use Rule (SNUR)
      24 substances have been added up on February 16, 2024 effectuation and 1 substance has been added up on January 11, 2024 publication.
  11. TSCA: Regulation of hazardous chemical substances and mixtures
      236 exemplified substances have been added by reviewing the data.
  12. ISHA: Risk Assessment Report
      52 items have been added based on the update of January 31, 2024.
  13. IARC: Carcinogenicity Assessment
      14 agents have been updated on December 6, 2023.
  14. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN: 3 links have been added.
  15. Japan MHLW: Toxicity Test Results
      5 substances have been added, 5 substances have been deleted based on the list of Japan Existing Chemical Database (JECDB) updated on December 2023.
  16. General Information: Chemical Substance Name
      434 substance names have been updated.
  17. General Information: Molecular formula, weight and SMILES
      405 molecular formula data and 369 SMILES data have been updated.
  18. General Information: Structure and Data for structure search
      Structures for 427 substances have been updated.
  19. Information of Japan Chemical Substance Dictionary (Nikkaji)
      61 substances have been added.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

January 30, 2024

Following information has been added newly.
  1. Japan ISHA: Concentration standards for the prevention of health problems caused by chemical substances (Concentration standard value setting substance)
      The standards for substances and concentrations specified by the Minister of Health, Labour and Welfare pursuant to the provisions of Article 577-2, Paragraph 2 of the Industrial Safety and Health Regulations (Notification No. 177 of the Ministry of Health, Labour and Welfare, 2023) have been posted.
  2. Japan ISHA: Chemical substances that cause skin disorders, etc. and other chemical substances that must be handled with impermeable protective equipment etc. based on special chemical regulations.
      List of the Chemical substances that must be handled with impervious protective equipment, etc. based on Article 594-2 of the ISH Ordinance and special chemical regulations has been posted.
  3. Fire Service Act : Hazardous Materials
      Dangerous Substnces have been posted, that are based on Fire Service Act and Cabinet Order Concerning the Control of Hazardous Materials.
  4. Fire Service Act : Designated Flammable Goods
      Designated Flammable Goods have been posted, that are based on Fire Service Act and Cabinet Order Concerning the Control of Hazardous Materials.
  5. Fire Service Act : Substances that inhibit firefighting activities
      Substances that inhibit firefighting activities have been posted. They are based on Fire Service Act, Cabinet Order Concerning the Control of Hazardous Materials, and Ordinance of the Ministry of Internal Affairs and Communications.
Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      Confirmed link of CAS RN: 1 link has been added.
  2. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 10 links have been added.
  3. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 16 links have been added.
  4. Japan CSCL: Type III Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 1 link has been added.
  5. Japan CSCL: Chemical Substances exempted from notification of manufacturing/import amount
      Confirmed link of CAS RN: 1 link has been added.
  6. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 5 links have been added.
  7. Japan ISHA: Newly Announced Chemical Substances
      178 substances (September 27, 2023 public notice) have been added.
  8. Japan ISHA: Organic Solvents
      4 exemplified substances have been added by reviewing the data.
  9. Japan ISHA: Strong Mutagenic Chemical Substances
      18 substances have been added and 1 substance has been deleted in Notified Chemical Substances based on the notification issued on November 30, 2023.
  10. Japan: Poisonous and Deleterious Substances Control Act
      1 exemplified substance of Deleterious Substances has been deleted by reviewing the data.
  11. UN Number and UN Hazard Class
      1 exemplified substances has been added by reviewing the data.
  12. EU: CLP Harmonised Classification
      28 substances have been added and 24 substances have been modified, based on Commission Delegated Regulation (EU) 2024/197 of 19 October 2023 amending Regulation (EC) No 1272/2008 as regards the harmonised classification and labelling of certain substances published on January 5, 2024.
  13. IARC: Carcinogenicity Assessment
      4 agents have been added and 1 agent has been deleted on the list updated on December. 6, 2023.
  14. EU: Carcinogenicity Assessment
      9 substances have been added and 1 category has been changed, based on Commission Delegated Regulation (EU) 2024/197 of October 19, 2023 amending Regulation (EC) No 1272/2008 as regards the harmonised classification and labelling of certain substances published on January 5, 2024.
  15. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN: 11 links have been added.
  16. General Information: Chemical Substance Name
      53 substances names have been updated.
  17. General Information: Molecular formula, weight and SMILES
      28 molecular formula data and 27 SMILES data have been updated.
  18. General Information: Structure and Data for structure search
      Structures for 44 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

November 28, 2023

Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      Confirmed link of CAS RN: 1 link has been added.                         
  2. Japan CSCL: Canceled Priority Assessment Chemical Substances
      Confirmed link of CAS RN: 10 links have been deleted.
  3. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 5 links have been added.
  4. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 24 links have been added.
  5. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 6 links have been added.
  6. Japan ISHA: Existing Chemical Substances
      Confirmed link of CAS RN: 1 link has been revised by reviewing the data.
  7. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc.
      4 exemplified substance have been added by reviewing the data.
  8. Japan: Poisonous and Deleterious Substances Control Act
      1 exemplified substance of Deleterious Substances has been added and another has been deleted by reviewing the data.
  9. Rotterdam Convention on the Prior Informed Consent Procedure for Certain Hazardous Chemicals and Pesticides in International Trade (PIC)
      Based on the notification effective October 22, 2023, 1 pesticide substance has been added.
  10. EU: CLP Harmonised Classification
      Confirmed link of CAS RN: 3 links have been added by reviewing the data.
  11. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      Based on the notification issued on August 1, 2023, 3 substances have been added and 4 percentage information have been changed in Toxic substance(s).
  12. GHS Aligned Sample Label and SDS
      48 substances have been added based on the list updated on August 16, 2023.
  13. Australia: Priority Existing Chemicals (PEC) Assessment Reports
      25 exemplified substances have been added and another has been deleted by reviewing the data.
  14. JSOH: Occupational Exposure Limits
      5 substances have been added based on the list of FY2023 publication.
  15. JSOH: Occupational Carcinogens
      3 substances have been added based on the list of FY2023 publication.
  16. JOSH: Occupational Sensitizers
      2 substances have been added based on the list of FY2023 publication.
  17. JSOH: Reproductive Toxicants
      1 substance (Group 3) has been added based on the list of FY2023 publication.
  18. EU: Carcinogenicity Assessment
      Confirmed link of CAS RN: 3 links have been added.
  19. Japan METI: Biodegradation and Bioconcentration Results
      The display method of the judgement results and the test results has been changed.
  20. General Information: Chemical Substance Name
      434 substance names have been updated.
  21. General Information: Molecular formula, weight and SMILES
      430 molecular formula data and 399 SMILES data have been updated.
  22. General Information: Structure and Data for structure search
      Structures for 416 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

October 20, 2023

Following data have been updated.
  1. Japan: PRTR-SDS Law (from April 2023)
       "List of Conversion Factors, etc. for metal compounds" has been updated as a reference for the PRTR-SDS Law (from April 2023).
October 3, 2023

Following data have been updated.
  1. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      Confirmed link of CAS RN: 53 links have been added.
  2. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 4 links have been added.
  3. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 28 links have been added.
      Confirmed link of CAS RN and The Japanese Pharmacopoeia 8th Edition chemicals: 4 links have been added.
  4. Japan CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 2 links have been added.
  5. Japan CSCL: Chemical Substances exempted from notification of manufacturing/import amount
      Confirmed link of CAS RN: 2 links have been added.
  6. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 7 links have been added.
  7. Japan ISHA: Newly Announced Chemical Substances
      148 substances (June 27, 2023 public notice) have been added.
  8. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc.
      In accordance with the amendment promulgated on August 30, 2023, 7 substances have been deleted and 1 substance has been changed.
  9. UN Number and UN Hazard Class
      12 UN numbers have been added according to the revised 23rd edition (2023) of the List of Dangerous Goods, and 8 product names and other items have been revised.
  10. REACH: Substances of Very High Concern for Authorization (SVHC)
      2 substances have been added for Candidate List. (Announced on June 14, 2023)
  11. EU: CLP Harmonised Classification
      4 substances have been added and note of 4 substances have been replaced, based on Commission delegated regulation (EU) 2023/1435 published on July 31, 2023.
  12. TSCA Inventory
      589 substances have been added, 16 names have been changed and ""ACTIVE"" information has been changed to 32 substances based on the list updated on August 2023.
  13. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      Based on the notification issued on June 1, 2023, 6 substances and 1 exemplified substance have been added, 1 name, 1 excepted substance and 4 percentage information have been changed in Toxic substance(s).
      Also reviewing the data, 2 exemplified substances has been added in Toxic substance(s).
  14. ISHA: Risk Assessment Report
      49 items have been added based on the update of August 4, 2023 and August 29, 2023.
  15. IARC: Carcinogenicity Assessment
      3 agents have been added and 2 agents have been updated on July 27, 2023.
  16. EU: Carcinogenicity Assessment
      15 substances have been added, based on Commission delegated regulation (EU) 2023/1435 published on July 31, 2023 and Commission delegated regulation (EU) 2022/692 published on May 3, 2022.
  17. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN: 55 links have been added.
  18. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
      1 report has been revised to new report based on the announcement on March 10, 2023.
      1 draft has been revised to new report based on the announcement on July 5, 2023.
  19. General Information: Chemical Substance Name
      70 substance names have been updated.
  20. General Information: Molecular formula, weight and SMILES
      60 molecular formula data and 51 SMILES data have been updated.
  21. General Information: Structure and Data for structure search
      Structures for 62 substances have been updated.
  22. Information of Japan Chemical Substance Dictionary (Nikkaji)
      706 substances have been added.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

July 31, 2023

Following information has been added newly.
  1. Japan ISHA: Carcinogenic Substances (Ordinance on Industrial Safety and Health) (subject to 30-year storage of work records, etc.)
      Based on the provisions of Article 577-2 of the Ordinance on Industrial Safety and Health, 206 carcinogenic substances, that are subject to storage of work records, etc. for 30 years, have been newly posted.
Following data have been updated.
  1. Japan CSCL: Monitoring Chemical Substances
      Confirmed link of CAS RN: 1 link has been added.
  2. Japan CSCL: Priority Assessment Chemical Substances
      Confirmed link of CAS RN: 22 links have been added and 2 links have been deleted.
  3. Japan CSCL: Canceled Priority Assessment Chemical Substances
      Confirmed link of CAS RN: 2 links have been added
  4. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      179 substances have been added based on the notification of June 31, 2023.
  5. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 8 links have been added.
  6. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 26 links have been added.
  7. Japan CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 6 links have been added.
  8. Japan CSCL: Type III Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 5 links have been added.
  9. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 19 links have been added and 1link has been revised.
  10. Japan: PRTR-SDS Law (until March 2023)
      Confirmed link of CAS RN: 1 link has been revised.
  11. Japan: PRTR-SDS Law (from April 2023)
      Confirmed link of CAS RN: 1 link has been revised.
  12. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc.
      3 exemplified substances have been added by reviewing the data.
  13. Japan ISHA: Specified Chemical Substances
      3 exemplified substances have been added by reviewing the data.
  14. Japan: Air Pollution Control Law
      1 substance name has been updated, 2 Confirmed links of CAS RN have been revised and 2 Confirmed links of CAS RN have been deleted by reviewing the data.
  15. High Pressure Gas Safety Act : Regulation on Safety of Refrigeration
      The display method of refrigerant names has been changed.
  16. TSCA: Significant New Use Rule (SNUR)
      28 substance URLs have been added and 5 substance CHRIP_IDs have been corrected.
  17. Korea: ARECs (K-REACH); Existing Chemical Substances
      4 substances have been deleted and names of 201 substances have been changed based on the notification issued on June 1, 2023.
  18. NITE Japan-GHS
      46 substances have been added, and 125 substances have been updated based on the June 29, 2023 update.
  19. GHS Classification Results by the Japanese Government
      171 classification results in 2022 have been added.
  20. Japan METI: Biodegradation and Bioconcentration Results
      The judgement results of Newly Announced Chemical Substances: 179 substances have been added. (published on July 31, 2023)
      Confirmed link of CAS RN: 5 link have been added.
  21. General Information: Chemical Substance Name
      97 substance names have been updated.
  22. General Information: Molecular formula, weight and SMILES
      91 molecular formula data and 44 SMILES data have been updated.
  23. General Information: Structure and Data for structure search
      Structures for 59 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

June 6, 2023

Following information has been added newly.
  1. NITE Japan-GHS
Following data have been updated.
  1. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 116 links have been added. 2 links have been deleted.
  2. Japan CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 12 links have been added.
  3. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 8 links added.
  4. Japan: PRTR-SDS Law (until March 2023)
      Confirmed link of CAS RN: 66 links have been added and 11 links have been deleted.
  5. Japan: PRTR-SDS Law (from April 2023)
      Confirmed link of CAS RN: 80 links have been added, and 17 links have been deleted.
  6. Japan ISHA: Existing Chemical Substance
      One composite record has been separated into two records by reviewing the data.
  7. Japan ISHA: Newly Announced Chemical Substances
      129 substances (March 27, 2023 public notice) have been added.
  8. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      In accordance with the provisions of Article 577-2-3 of the Ordinance on Industrial Safety and Health, "Carcinogenic Substances" has been displayed for 223 substances and 4 exemplified substances have been added.
  9. Japan ISHA: Specified Chemical Substances
      "Substances under special supervision" and "Detailed classification of Group-2 substances" have been displayed in the remarks column.
  10. Japan: Poisonous and Deleterious Substances Control Act
      1 Deleterious Substance has been added and 2 Cabinet Order Names have been modified based on the notification of May 26, 2023. 1 exemplified substance of Deleterious Substances has been added by reviewing the data.
  11. Japan: Air Pollution Control Law
      393 substances have been added by reviewing the data.
  12. High Pressure Gas Safety Act
      30 exemplified substances have been added by reviewing the data.
  13. High Pressure Gas Safety Act : Regulation on Safety of General High Pressure Gas
      10 Substances have been added and 16 Substances have been deleted by reviewing the data.
  14. High Pressure Gas Safety Act : Regulation on Safety of Refrigeration
      123 Refrigerants have been added by reviewing the data. The ASHRAE number has been displayed in the remarks column.
  15. EU: CLP Harmonised Classification
      Notes listed in Annex Vi Table 3 of the CLP Regulations have been displayed for 942 substances.
  16. TSCA: Significant New Use Rule (SNUR)
      57 rules have been added up to June 12, 2023 effectuation.
  17. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      1 exemplified substance has been added in Toxic substance(s) by reviewing the data.
  18. Korea: ARECs (K-REACH); Existing Chemical Substances
      1 exemplified substance has been added by reviewing the data.
  19. GHS Classification Results by the Japanese Government
      Confirmed link of CAS RN: 1 link has been added.
  20. US EPA: Integrated Risk Information System (IRIS)
      2 substances have been added by the list updated in April, 2023.
  21. IARC: Carcinogenicity Assessment
      3 agents have been added and 11 agents have been changed on the list updated on May 5, 2023.
  22. US EPA: Carcinogenicity Assessment
      1 agent have been added on the list updated on April 10, 2023.
  23. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN: 13 links have been added.
  24. Japan ISHA: Carcinogenicity Test Results for Chemical Substances
      1 substance has been added based on the update of MHLW web site.
  25. General Information: Chemical Substance Name
      676 substance names have been updated.
  26. General Information: Molecular formula, weight and SMILES
      635 molecular formula data and 402 SMILES data have been updated.
  27. General Information: Structure and Data for structure search
      Structures for 471 substances have been updated.
  28. Information of Japan Chemical Substance Dictionary (Nikkaji)
      1,033 substances have been added.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

April 3, 2023

Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      6 substances have been added based on the designation of April 1, 2023.
      6 substances have been deleted based on the cancellation of March 31, 2023.
      Confirmed link of CAS RN: 82 links have been added and 11 links have been deleted.
  2. Japan CSCL: Canceled Priority Assessment Chemical Substances
      6 substances have been added based on the cancellation of March 31, 2023.
      Confirmed link of CAS RN: 11 links have been added.
  3. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      Confirmed link of CAS RN: 1 link has been added.
  4. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 70 links have been added. and 9 links have been deleted.
  5. Japan CSCL: Chemical Substances exempted from notification of manufacturing/import amount
      105 substances have been added based on the notification of March 31, 2023.
      Confirmed link of CAS RN: 14 links have been added.
  6. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 14 links added, 4 links has been revised.
  7. Japan ISHA: Existing Chemical Substances
      Confirmed link of CAS RN: 1 link has been revised by reviewing the data.
  8. Japan: Poisonous and Deleterious Substances Control Act
      1 example of Poisonous Substances was added, 1 example of Deleterious Substances was changed to another Cabinet Order Name, and 3 examples were deleted by reviewing the data.
  9. Explosives Control Act
      Revised the configulation of data display.
  10. High Pressure Gas Safety Act: Regulation on Safety of General High Pressure Gas
      1 substance has been deleted by reviewing the data.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

March 14, 2023

Following information has been added newly.
  1. High Pressure Gas Safety Act
  2. High Pressure Gas Safety Act: Regulation on Safety of General High Pressure Gas
  3. High Pressure Gas Safety Act: Regulation on Safety of Refrigeration
  4. Explosives Control Act
Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      Confirmed link of CAS RN: 1 link has been added.
  2. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 1 link has been revised.
  3. Japan: PRTR-SDS Law (until March 2023)
      Confirmed link of CAS RN: 66 links have been added and 2 links have been deleted.
  4. Japan: PRTR-SDS Law (from April 2023)
      Confirmed link of CAS RN: 105 links have been added, and 6 links have been deleted.
  5. Japan ISHA: Existing Chemical Substances
      1 Confirmed link of CAS RN has been revised by reviewing the data.
  6. Japan ISHA: Newly Announced Chemical Substances
      181 substances have been added on the notification of December 27, 2022.
  7. Japan: Water Pollution Prevention Act
      51exemplified substances have been added by reviewing the data and 74 exemplified substances have been added based on the list of December 23, 2022 publication.
  8. UN Number and UN Hazard Class
      Added 2 display items corresponding to UN number.
        1) Subsidiary hazard, 2) UN packing group
  9. REACH: Substances of Very High Concern for Authorization (SVHC)
      9 substances have been added for Candidate List based on the notification of January 17, 2023.
  10. TSCA Inventory
      392 substances have been added, 11 names have been changed and ""ACTIVE"" information has been added to 55 substances based on the list updated on February 2023.
  11. General Information: Chemical Substance Name
      627 substance names have been updated.
  12. General Information: Molecular formula, weight and SMILES
      605 molecular formula data, 1 molecular weight data and 379 SMILES data have been updated.
  13. General Information: Structure and Data for structure search
      Structures for 397 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

January 31, 2023 

Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      Confirmed link of CAS RN:1 link has been added.
  2. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 11 links have been added. 1link has been deleted.
  3. Japan CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 1link has been added.
  4. Japan CSCL: Type III Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 1link has been added.
  5. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 1 link has been added.
  6. Japan: PRTR-SDS Law (until March 2023)
      Confirmed link of CAS RN: 1 link has been added.
  7. Japan: PRTR-SDS Law (from April 2023)
      Confirmed link of CAS RN: 1 link has been added.
  8. Japan ISHA: Existing Chemical Substances
      1 Confirmed link of CAS RN has been revised by reviewing the data.
  9. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      2 exemplified substance have been added by reviewing the data.
  10. Japan ISHA: Strong Mutagenic Chemical Substances
      33 substances have been added in Notified Chemical Substances based on the notification issued on December 7, 2022.
  11. UN Number and UN Hazard Class
      19 exemplified substances have been added by reviewing the data.
  12. HS Code: Section VI “Products of the Chemical or Allied Industries”
      The 2022 data has been reflected.
  13. EC Inventory
      Confirmed link of CAS RN: 3links have been added.
  14. REACH: Substances of Very High Concern for Authorization (SVHC)
      5 exemplified substances have been added by reviewing the data.
  15. TSCA: Significant New Use Rule (SNUR)
      24 rules have been added up on November 28, 2022 effectuation and 32 rules have been added up on January 31, 2023 effectuation.
  16. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      Based on the notification issued on December 7, 2022, 14 substances have been added and names of 5 substances have been changed and ranges of application of 9 substances have been changed and 1 exemplified substances have been added in Toxic substance(s).
  17. US EPA: Carcinogenicity Assessment
      4 agents have been added on the list updated on December 22, 2022.
  18. EU: Carcinogenicity Assessment
      3 substances have been added by reviewing the data.
  19. Safety Summary of Japan(JCIA BIGDr)
      4 substances have been added based on the list updated on September 12, 2022.
  20. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN:1 link has been added.
  21. Japan MHLW: Toxicity Test Results
       20 substances have been added.
  22. Japan ISHA: Carcinogenicity Test Results for Chemical Substances
      1 substance has been added based on the update of October 25, 2022.
  23. General Information: Chemical Substance Name
      376 substance names have been updated.
  24. General Information: Molecular formula, weight and SMILES
      369 molecular formula data and 339 SMILES data have been updated.
  25. General Information: Structure and Data for structure search
      Structures for 353 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

November 29, 2022 

Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      Confirmed link of CAS RN:94 links have been added.
  2. Japan CSCL: Canceled Priority Assessment Chemical Substances
       Confirmed link of CAS RN: 3 links have been added.
  3. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN :5 links have been added.
  4. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 17 links have been added.
  5. Japan CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 3 links have been added.
  6. Japan CSCL: Type III Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 3 link have been added.
  7. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 54 links has been added.
  8. Japan ISHA: Existing Chemical Substances
      1 Confirmed link of CAS RN has been revised by reviewing the data.
  9. Japan ISHA: Newly Announced Chemical Substances
      172 substances (September 27, 2022 public notice) have been added.
  10. Japan: Poisonous and Deleterious Substances Control Act
      2 examples of deleterious substances were deleted by reviewing the data.
  11. Japan: Poisonous and Deleterious Substances Control Act: Substances excluded from Organic cyanide compounds
      2 exemplified substances were added by reviewing the data.
  12. UN Number and UN Hazard Class
      72 exemplified substances have been added by reviewing the data.
  13. Rotterdam Convention on the Prior Informed Consent Procedure for Certain Hazardous Chemicals and Pesticides in International Trade (PIC)
      2 industrial chemical substances (5 exemplified substances) have been added to the Industrial. (Effective on October 21, 2022)
  14. EU: CLP Harmonised Classification
      Based on the ATP18 of May 03, 2022 publication, 39 substances have been added and 1 substance has been deleted. Confirmed link of CAS RN: 299 links have been added, 4 links have been deleted.
  15. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      Based on the notification issued on October 6, 2022, 11 substances have been added and names of 4 substances have been changed and ranges of application of 20 substances have been changed and 17 exemplified substances have been added in Toxic substance(s).
  16. International Chemical Safety Cards (ICSC)
      8 ICSCs have been deleted, 3 exemplified substances have been added and 2 exemplified substances have been deleted by reviewing the data.
  17. JSOH: Occupational Exposure Limits
      2 substances have been added based on the list of FY2022 publication.
  18. JSOH: Occupational Carcinogens
      4 substances have been added and 1 substance has been changed from 2B to 2A based on the list of FY2022 publication.
  19. JOSH: Occupational Sensitizers
      3 substances have been added based on the list of FY2022 publication.
  20. JSOH: Reproductive Toxicants
      1 substances has been added based on the list of FY2022 publication.
  21. IARC: Carcinogenicity Assessment
      5 agents have been added and 1 agent has been deleted on the list updated on September 7, 2022.
  22. EU: Carcinogenicity Assessment
      2 substances have been added and 7 substances have been deleted by reviewing the data.
  23. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN:11 links have been added.
  24. General Information: Chemical Substance Name
      1066 substance names have been updated.
  25. General Information: Molecular formula, weight and SMILES
      710 molecular formula data and 724 SMILES data have been updated.
  26. General Information: Structure and Data for structure search
      Structures for 686 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

October 11, 2022 

Following data have been updated.
  1. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      Confirmed link of CAS RN :55 links have been added.
  2. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN :3 links have been deletd, 1 link has been deletd.
  3. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 11 links have been added.
  4. Japan CSCL: Chemical Substances exempted from notification of manufacturing/import amount
       Confirmed link of CAS RN: 1 link has been added.
  5. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 1 links has been added.
  6. Japan ISHA: Newly Announced Chemical Substances
      230 substances (June 27, 2022 public notice) have been added.
      Confirmed links of CAS RN: 8 links have been added.
  7. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      7 exemplified substance have been added by reviewing the data.
  8. Japan ISHA: Specified Chemical Substances
      1 exemplified substance has been added by reviewing the data.
  9. Japan: Poisonous and Deleterious Substances Control Act
      20 examples of poisonous and deleterious substances were added by reviewing the data.
  10. EC Inventory
      Confirmed link of CAS RN: 2655 links have been added.
  11. REACH: Substances of Very High Concern for Authorization (SVHC)
      8 exemplified substances have been deleted by reviewing the data.
  12. TSCA Inventory
      1 substance name has been changed based on the list updated in February 2022.
  13. TSCA: Significant New Use Rule (SNUR)
      20 rules have been added up on August 26, 2022 effectuation.
  14. TSCA: Prioritization, risk evaluation, and regulation of chemical substances and mixtures
      Section catchline has been changed from "Regulation of hazardous chemical substances and mixtures" to " Prioritization, risk evaluation, and regulation of chemical substances and mixtures".
  15. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      Based on the notification issued on April 27, 2022, data has been updated in Substances subject to intensive control.
  16. GHS Classification Results by the Japanese Government
      GHS Classification Result by the Japanese Government in FY2021, 233 substances have been added.
  17. GHS Aligned Sample Label and SDS
      13 substances have been added based on the list updated on July 19, 2022.
  18. IARC: Carcinogenicity Assessment
      1 agent has been changed from 2B to 1 group on the list updated on July 1, 2022.
  19. Japan METI: Biodegradation and Bioconcentration Results
       The judgement results of Newly Announced Chemical Substances:185 substances have been added. (published on July 29, 2022)
      Confirmed link of CAS RN: 59 links have been added.
  20. General Information: Chemical Substance Name
      202 substance names have been updated.
  21. General Information: Molecular formula, weight and SMILES
      162 molecular formula data and 153 SMILES data have been updated.
  22. General Information: Structure and Data for structure search
      Structures for 160 substances have been updated.
  23. Information of Japan Chemical Substance Dictionary (Nikkaji)
      198 substances have been added."
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

July 29, 2022 

Following data have been updated.
  1. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      185 substances have been added based on the notification of June 29, 2022.
  2. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 3 links have been added, 1link has been revised.
  3. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 127 links have been added. 1 link has been deleted.
  4. Japan CSCL: Type III Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 2 link have been added.
  5. Japan CSCL: Chemical Substances exempted from notification of manufacturing/import amount
       Confirmed link of CAS RN: 1 link has been deleted.
  6. Japan: PRTR-SDS Law (from April 2023)
      Confirmed link of CAS RN: 1 link has been added
  7. Japan ISHA: Newly Announced Chemical Substances
      209 substances (March 25, 2022 public notice) have been added.
      Name of 6 substances (March 31, 2022 public notice) have been revised.
  8. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      2 exemplified substances have been deleted by reviewing the data.
  9. REACH: Substances of Very High Concern for Authorization (SVHC)
      1 substance has been added to the Candidate List of SVHCs. (Announced on June 10, 2022)
  10. IARC: Carcinogenicity Assessment
      8 agents have been added, 2 agents have been deleted and 1 agent has been changed from 2B to 2A group on the list updated on April 08, 2022.
  11. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN: 1 link has been added.
  12. General Information: Chemical Substance Name
      890 substance names have been updated.
  13. General Information: Molecular formula, weight and SMILES
      881 molecular formula data and 877 SMILES data have been updated.
  14. General Information: Structure and Data for structure search
      Structures for 880 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

May 31, 2022 

Following data have been updated.
  1. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 2 links have been added, 1link has been deleted.
  2. Japan CSCL: Existing Chemical Substances
       Confirmed link of CAS RN: 96 links have been added. 3 links have been deleted.
  3. Japan CSCL: Chemical Substances exempted from notification of manufacturing/import amount
       Confirmed link of CAS RN: 1 link has been added.
  4. Japan: PRTR-SDS Law (until March 2023)
      Confirmed link of CAS RN: 237 links have been added
  5. Japan: PRTR-SDS Law (from April 2023)
      Confirmed link of CAS RN: 36 links have been added
  6. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      In accordance with the amendment promulgated on February 24, 2022, 234 substances were added.
  7. Japan: Air Pollution Control Law
      By reviewing the data, 82 exemplified substances have been added.
  8. REACH: Substances of Very High Concern for Authorization (SVHC)
      5 substances have been added to REACH Authorisation List. (Announced on April 11, 2022)
  9. TSCA Inventory
      385 substances have been added, 45 ACTIVITYs have been changed, based on the list updated in February 2022.
  10. US Agency for Toxic Substances and Disease Registry (ATSDR) Toxicological Profiles
      13 exemplified substances have been added based the information on April 27, 2022.
  11. Safety Summary of Japan(JCIA BIGDr)
      21 substances have been added, names of 1 substance have been changed based on the list updated on January 11, 2022.
  12. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN: 2 links have been added, 1link has been deleted.
  13. General Information: Chemical Substance Name
      217 substance names have been updated.
  14. General Information: Molecular formula, weight and SMILES
       23 molecular formula data and 11 SMILES data have been updated.
  15. General Information: Structure and Data for structure search
      Structures for 14 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

April 1, 2022 

Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      4 substances have been added based on the notification of April 1, 2022.
      13 substances have been deleted based on the notification of March 31, 2022.
      Confirmed link of CAS RN: 39 links have been added and 20 links have been deleted.
  2. Japan CSCL: Canceled Priority Assessment Chemical Substances
      13 substances have been added based on the notification of March 31, 2022.
      Confirmed link of CAS RN: 20 links have been added.
  3. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      Confirmed link of CAS RN:4 links have been added.
  4. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 2 links have been added.
  5. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 43 links have been added. 14 link has been deleted.
  6. Japan CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 3 links have been added.
  7. Japan CSCL: Type III Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 1 link has been added.
  8. Japan CSCL: Chemical Substances exempted from notification of manufacturing/import amount
      132 substances have been added based on the notification of March 31, 2022
      Confirmed link of CAS RN: 8 links have been added.
  9. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 17 links have been added.
  10. Japan: PRTR-SDS Law (until March 2023)
      1 Confirmed link of CAS RN has been changed.
  11. Japan ISHA: Newly Announced Chemical Substances
      196 substances (December 27, 2021 public notice) have been added.
      Confirmed links of CAS RN: 2 links have been revised.
  12. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN:7 links have been added.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

March 15, 2022 

Following data have been updated.
  1. Japan: PRTR-SDS Law (until March 2023)
      Added Remarks
  2. Japan: PRTR-SDS Law (from April 2023)
      242 exemplified substances have been added and 1 exemplified substance has been deleted.
  3. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      1,292 exemplified substance have been added by reviewing the data.
  4. Japan: Poisonous and Deleterious Substances Control Act
      Revised 2 "Law or Cabinet Order name" and added 2 deleterious substances to reflect the revision of the cabinet order of January 28, 2022. In addition, 17 examples of deleterious substances were added by reviewing the data.
  5. Japan: Poisonous and Deleterious Substances Control Act: Substances excluded from Organic cyanide compounds
      1 substance has been added based on the notification of January 28, 2022.
  6. REACH: Substances of Very High Concern for Authorization (SVHC)
      4 substances have been added for Candidate List. (Announced on January 17, 2022)
  7. TSCA: Significant New Use Rule (SNUR)
      45 rules have been added up on February 8, 2022 effectuation.
  8. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      Based on the notification issued on December 28, 2021, 5 substances have been added and 1 substance has been deleted and names of 4 substances have been changed and ranges of application of 3 substances have been changed and 3 exemplified substances have been added and 1 exemplified substances have been deleted in Toxic substance(s). Based on the notification issued on December 29, 2021, 1 substance has been added and ranges of application of 1 substance has been changed and 1 exemplified substances have been added in Restricted Substance(s).
  9. GHS Classification Results by the Japanese Government
      GHS Classification Result by the Japanese Government in FY2021, 25 substances to be released in advance have been added.
  10. US NTP: Carcinogenicity Assessment
      Based on the 15th Report on Carcinogens of December 21, 2021 publication, 3 substances have been added.
  11. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
      1 draft has been revised to full report based on the announcement on December 27, 2021.
  12. General Information: Chemical Substance Name
      182 substance names have been updated.
  13. General Information: Molecular formula, weight and SMILES
      144 molecular formula data and 114 SMILES data have been updated.
  14. General Information: Structure and Data for structure search
      Structures for 123 substances have been updated.
  15. Information of Japan Chemical Substance Dictionary (Nikkaji)
      222 substances have been added."
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

January 25, 2022 

Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      Confirmed link of CAS RN: 40 links have been added.
  2. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 64 links have been added. 1 link has been deleted.
  3. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 7 links have been added.
  4. Japan: PRTR-SDS Law (from April 2023)
      74 exemplified substances have been added and 2 exemplified substances have been deleted.
  5. Japan ISHA: Newly Announced Chemical Substances
      195 substances (September 27, 2021 and Novemver 25, 2021 public notice) have been added. Name of 3 substances (October 29, 2021 public notice) have been revised.Confirmed links of CAS RN: 1 link has been revised.
  6. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      1 exemplified substance has been added by reviewing the data.
  7. Japan ISHA: Strong Mutagenic Chemical Substances
      15 substances have been added in Notified Chemical Substances, and 2 substances have been added in Existing Chemical Substances, based on the notification issued on November 25, 2021.
  8. TSCA: Significant New Use Rule (SNUR)
      8 rules have been added up to January 14, 2022 effectuation.
  9. TaiwanTCCSCA/OSHA: Existing Chemical Substances
      224 substances have been added based on the list updated on November, 2020.
  10. ISHA: Examples of Occupational Accidents Caused by Chemical Substances
      7 substances have been added and 1 confirmed rink of CAS RN has been revised based on the list of December 13, 2021 updated.
  11. International Chemical Safety Cards (ICSC)
      ICSC card have been added based on July 21, 2020.
  12. Advisory Committee on Existing Chemicals (BUA) Reports by the German Chemical Society
      5 agents have been deleted and 36 agents have changed based on July 7, 2021.
  13. IARC: Carcinogenicity Assessment
      3 agents have been added ,1 agent has been deleted and 2 groups have been changed on the list updated on November 30, 2021.
  14. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
      2 drafts have been added and 4 drafts have been revised to full report based on the announcement on December 2, 2021.
  15. General Information: Chemical Substance Name
      329 substance names have been updated.
  16. General Information: Molecular formula, weight and SMILES
      304 molecular formula data and 184 SMILES data have been updated.
  17. General Information: Structure and Data for structure search
      Structures for 200 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

January 25, 2022 

Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      Confirmed link of CAS RN: 40 links have been added.
  2. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 64 links have been added. 1 link has been deleted.
  3. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 7 links have been added.
  4. Japan: PRTR-SDS Law (from April 2023)
      74 exemplified substances have been added and 2 exemplified substances have been deleted.
  5. Japan ISHA: Newly Announced Chemical Substances
      195 substances (September 27, 2021 and Novemver 25, 2021 public notice) have been added. Name of 3 substances (October 29, 2021 public notice) have been revised.Confirmed links of CAS RN: 1 link has been revised.
  6. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      1 exemplified substance has been added by reviewing the data.
  7. Japan ISHA: Strong Mutagenic Chemical Substances
      15 substances have been added in Notified Chemical Substances, and 2 substances have been added in Existing Chemical Substances, based on the notification issued on November 25, 2021.
  8. TSCA: Significant New Use Rule (SNUR)
      8 rules have been added up to January 14, 2022 effectuation.
  9. TaiwanTCCSCA/OSHA: Existing Chemical Substances
      224 substances have been added based on the list updated on November, 2020.
  10. ISHA: Examples of Occupational Accidents Caused by Chemical Substances
      7 substances have been added and 1 confirmed rink of CAS RN has been revised based on the list of December 13, 2021 updated.
  11. International Chemical Safety Cards (ICSC)
      ICSC card have been added based on July 21, 2020.
  12. Advisory Committee on Existing Chemicals (BUA) Reports by the German Chemical Society
      5 agents have been deleted and 36 agents have changed based on July 7, 2021.
  13. IARC: Carcinogenicity Assessment
      3 agents have been added ,1 agent has been deleted and 2 groups have been changed on the list updated on November 30, 2021.
  14. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
      2 drafts have been added and 4 drafts have been revised to full report based on the announcement on December 2, 2021.
  15. General Information: Chemical Substance Name
      329 substance names have been updated.
  16. General Information: Molecular formula, weight and SMILES
      304 molecular formula data and 184 SMILES data have been updated.
  17. General Information: Structure and Data for structure search
      Structures for 200 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

November 30, 2021 

Following data have been updated.
  1. Japan CSCL: Class I Specified Chemical Substances
       1 substances has been added and 1 substances has been revised its name based on the notifications of April 21, 2021.
  2. Japan CSCL: Priority Assessment Chemical Substances
      Confirmed link of CAS RN: 2 links have been added.
  3. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      Confirmed link of CAS RN: 41 links have been added.
  4. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 6 links have been added. 1 links has been deleted.
  5. Japan CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 4 links have been added.
  6. Japan CSCL: Chemical Substances exempted from notification of manufacturing/import amount
      Confirmed link of CAS RN: 1 link has been added.
  7. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 13 links have been added.
  8. Japan: PRTR-SDS Law (until March 2023)
      1 exemplified substances have been added by reviewing the data.
  9. Japan: PRTR-SDS Law (from April 2023)
      Following information has been added newly.
      Japan: Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof (PRTR-SDS Law)((Promulgated October 20, 2021;Not enforced)
      649 substances (exemplified substances 10,843) have been posted
  10. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      2 exemplified substance has been added by reviewing the data.
  11. Japan ISHA: Newly Announced Chemical Substances
      192substances (June 25, 2021 public notice) have been added.
  12. UN Number and UN Hazard Class
      1 UN Number has been added ,1 UN number has been deleted and 4 names have been changed, based on the Dangerous Goods List of Rev. 22 (2021).
  13. Stockholm Convention on Persistent Organic Pollutants (POPs)
      2 substances have been added in Annex A . (Effective December 3, 2020)
  14. TSCA: Significant New Use Rule (SNUR)
      86 rules have been added up to November 30, 2021 effectuation.
  15. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      Based on the notification issued on September 13, 2021 substances have been added and name of 1 substance has been changed and 3 exemplified substances have been added in Toxic substance(s).
  16. GHS Aligned Sample Label and SDS
      28 substances have been added based on the list updated on August 5, 2021.
  17. JSOH: Occupational Exposure Limits
      1 substance has been added and 12 substance has been revised based on the list of FY2021 publication.
  18. JSOH: Occupational Exposure Limits Based on Biological Monitoring
      2 substances have been added based on the list of FY2021 publication.
  19. JSOH: Occupational Carcinogens
      7 substances have been added based on the list of FY2021 publication.
  20. JOSH: Occupational Sensitizers
      3 substances have been added based on the list of FY2021 publication.
  21. Japan METI: Biodegradation and Bioconcentration Results
      The judgement results of Newly Announced Chemical Substances: 206 substances have been added. (published on October 11, 2021)
      Confirmed link of CAS RN: 42 links have been added.
  22. Japan MHLW: Toxicity Test Results
      7 substances have been added based on the list of Japan Existing Chemical Database (JECDB) updated on October 2021.
  23. General Information: Chemical Substance Name
      403 substance names have been updated.
  24. General Information: Molecular formula, weight and SMILES
      396 molecular formula data and 1350 SMILES data have been updated.
  25. General Information: Structure and Data for structure search
      Structures for 387 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

October 05, 2021 

Following data have been updated.
  1. Japan ISHA: Newly Announced Chemical Substances
      187 substances (March 26, 2021 public notice) have been added.
  2. Japan ISHA: Strong Mutagenic Chemical Substances
      Confirmed link of CAS RN: 1 link has been revised.
  3. Japan: Water Pollution Control Law
      1 exemplified substance has been added by reviewing the data.
  4. EU: CLP Harmonised Classification
      23 substances have been added, 1 substance has been deleted and the entries of 38 substances have been replaced, based on the Official Journal of the European Union (ATP 17th) published on May 28, 2021.
  5. TSCA Inventory
      24 substances have been added, 4 names have been changed and ""ACTIVE"" information has been added to 30 substances based on the list updated on October 2021.
  6. TSCA: Significant New Use Rule (SNUR)
      22 rules have been added up to August 6, 2021 effectuation.
  7. US Agency for Toxic Substances and Disease Registry (ATSDR) Toxicological Profiles
      8 issued data of the Profile have been changed and 1 data of the Profile has been deleted, and 10 exemplified substances have been added and 1 exemplified substance has been deleted based on the information of September 1, 2021.
  8. US EPA: Integrated Risk Information System (IRIS)
      Publication date of 2 substances have been changed on the List updated on August, 2021.
  9. IARC: Carcinogenicity Assessment
      Iissued dates of 1 agent has been chaned on the list updated on July 22, 2021.
  10. US EPA: Carcinogenicity Assessment
      2 agents have been added on the list updated on August 13, 2021.
  11. EU: Carcinogenicity Assessment
      9 substances have been added and the carcinogenicity classification of 2 substances have been changed from 2 to 1B, based on the Official Journal of the European Union published on May 28, 2021.
  12. General Information: Chemical Substance Name
      1,011 substance names have been updated.
  13. General Information: Molecular formula, weight
      1,007 molecular formula data have been updated.
  14. General Information: Structure and Data for structure search
      Structures for 1,005 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

July 30, 2021 

Following data have been updated.
  1. Information of Japan Chemical Substance Dictionary (Nikkaji)
      530 substances have been added.
  2. Japan CSCL: Class I Specified Chemical Substances
      Confirmed link of CAS RN: 17 links have been added.
  3. Japan CSCL: Canceled Priority Assessment Chemical Substances
      From this time, we have started posting the Canceled Priority Assessment Chemical Substances.
  4. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      206 Substances have been added based on the notification of July 30, 2021.
  5. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 87 links have been added. 3 links have been deleted.
  6. Japan CSCL: Type III Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 12 links have been added.
  7. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      10 exemplified substance has been added by reviewing the data.
  8. Japan: Poisonous and Deleterious Substances Control Act
      Corrected the English description regarding the exclusion of one deleterious substance(Article 2-1-62 of Cabinet order).
  9. REACH: Substances of Very High Concern for Authorization (SVHC)
      8 substances have been added for Candidate List. (Announced on July 8, 2021)
  10. TSCA: Significant New Use Rule (SNUR)
      15 rules have been added up to July 6, 2021 effectuation.
  11. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      Based on the notification issued on June 22, 2021, 19 substances have been added and names of 4 substance have been changed and ranges of application of 10 substances have been changed and 18 exemplified substance have been added in Toxic substance(s).
  12. IARC: Carcinogenicity Assessment
      Iissued dates of 6 agents have been chaned on the list updated on June 29, 2021.
  13. Safety Summary of Japan(JCIA BIGDr)
      2 substances have been added, names of 7 substances have been changed based on the list updated on June 14, 2021.
  14. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN: 12 links have been added.
  15. General Information: Chemical Substance Name
      367 substance names have been updated.
  16. General Information: Molecular formula, weight and SMILES
      247 molecular formula data and 240 SMILES data have been updated.
  17. General Information: Structure and Data for structure search
      Structures for 179 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

June 8, 2021 

Following data have been updated.
  1. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      5 exemplified substance has been added by reviewing the data.
  2. Japan: Poisonous and Deleterious Substances Control Act
      19 Deleterious Substances have been added and 2 Deleterious Substances have been deleted by reviewing the data.
  3. TSCA: Significant New Use Rule (SNUR)
      3 rules have been added up to May 21, 2021 effectuation.
  4. GHS Classification Results by the Japanese Government
      253 classification results in 2020 have been added.
  5. GHS Aligned Sample Label and SDS
      30 substances have been added based on the list updated on January 29, 2021.
  6. US Agency for Toxic Substances and Disease Registry (ATSDR) Toxicological Profiles
      1 issued data of the Profile has been changed, 2 exemplified substances have been added and 2 exemplified substances have been deleted based on the information of May 5, 2021.
  7. General Information: Chemical Substance Name
      11 substance names have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

April 20, 2021 

Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      6 substances have been added based on the notification of April 1, 2021.
      5 substances have been deleted based on the notification of March 31, 2021.
      Confirmed link of CAS RN: 37 links have been added and 5 links have been deleted.
  2. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      Confirmed link of CAS RN: 5 links have been added.
  3. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 23 links have been added.
  4. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 94 links have been added and 2 links have been deleted.
  5. Japan CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 1 links has been added.
  6. Japan CSCL: Chemical Substances exempted from notification of manufacturing/import amount
      Confirmed link of CAS RN: 9 links have been added.
  7. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 203 links have been added.
  8. Japan ISHA: Newly Announced Chemical Substances
      183 substances (December 25, 2020 public notice) have been added.
      Confirmed links of CAS RN: 2 links have been revised (according to the MHLW website).
  9. Japan ISHA: Specified Chemical Substances
      As the notification on April 22, 2020 came into effect on April 1, 2021, 3 related Cabinet Order names were revised and 1 was deleted.
  10. Japan ISHA: Administrative Control Levels of Working Environment Evaluation Standards
      As the notification on April 22, 2020 came into effect on April 1, 2021, 1 related Cabinet Order name was revised and 1 was deleted.
  11. Japan: Soil Contamination Countermeasures Act
      2 standard values of substances have been changed on public notice April 2, 2020.
  12. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      Based on the notification issued on February 22, 2021, 29 substances have been added and name of 1 substance has been changed and 1 exemplified substance has been added in Toxic substance(s).
  13. US Agency for Toxic Substances and Disease Registry (ATSDR) Toxicological Profiles
      3 issued data of the Profiles has been changed based on the information of March 16, 2021.
  14. US EPA: Integrated Risk Information System (IRIS)
      2 substances have been added, 2 substance has been deleted and 3 chemical names have been changed on the List updated on February, 2021.
  15. IARC: Carcinogenicity Assessment
      6 agents have been added, and 1 chemical name has been changed and on the list updated on March 26, 2021.
  16. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN: 20 links have been added.
  17. General Information: Chemical Substance Name
      6 substance names have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

March 9, 2021 

Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      Confirmed link of CAS RN: 2 links have been added.
  2. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      Confirmed link of CAS RN: 47 links have been added.
  3. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 1 link has been added. 3 links have been deleted.
  4. Japan CSCL: Type III Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 1 link has been added.
  5. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 2 links have been added.
  6. Japan ISHA: Strong Mutagenic Chemical Substances
      27 substances have been added in Notified Chemical Substances, and 5 substances have been added in Existing Chemical Substances, based on the notification issued on 2020/12/7.
  7. REACH: Substances of Very High Concern for Authorization (SVHC)
      2 substances have been added for Candidate List. (2021/1/19 announced)
  8. TSCA Inventory
      77 substances have been added, 1 substance has been deleated,7 names have been changed and "ACTIVE" information has been added to 84 substances based on the list updated on 2021/02/09.
  9. TSCA: Significant New Use Rule (SNUR)
      6 rules have been added up to 2021/2/5 effectuation.
  10. TSCA: Regulation of hazardous chemical substances and mixtures
      5 substances have been added up to 2021/02/05 effectuation.
  11. Korea: ARECs (K-REACH); Existing Chemical Substances
      4 substances have been deleted and names of 231 substances have been changed based on the notification issued on 2021/2/5.
  12. US Agency for Toxic Substances and Disease Registry (ATSDR) Toxicological Profiles
      Information suchc as the date of issue has been added.
  13. US EPA: Carcinogenicity Assessment
      One agent has been changed on the list updated on 2021/02/08.
  14. Safety Summary of Japan(JCIA BIGDr)
      4 substances have been added, names of 1 substances have been changed based on the list updated on January 21, 2021.
  15. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN: 48 links have been added.
  16. General Information: Chemical Substance Name
      241 substance names have been updated.
  17. General Information: Molecular formula, weight and SMILES
      233 molecular formula data and 220 SMILES data have been updated.
  18. General Information: Structure and Data for structure search
      Structures for 249 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

Following content has been updated.
  1. FAQ
      It has been renewed.
  2. Manual,etc.
      a new page such as a manual has been created.It is posted materials that can be used as a reference for searching when using NITE-CHRIP.
January 26, 2021 

Following data have been updated.
  1. Japan: Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
      26 exemplified substances have been added by reviewing the data.
  2. Japan ISHA: Newly Announced Chemical Substances
      167 substances (2020/09/25 public notice) have been added.
      Substance name:2 names have been revised (according to the MHLW website).
  3. Japan ISHA: Chemical Substances requiring Labeling and Delivery of Documents, etc
      1 exemplified substance has been added by reviewing the data.
  4. IARC: Carcinogenicity Assessment
      1 agent has been added and 2 agents have changed on the list updated on 2020/12/02.
  5. General Information: Chemical Substance Name
      350 substance names have been updated.
  6. General Information: Molecular formula, weight and SMILES
      113 molecular formula data, 1 molecular weight data and 93 SMILES data have been updated.
  7. General Information: Structure and Data for structure search
      Structures for 114 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

December 14, 2020 

Following data have been updated.
  1. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 1 link has been deleted.
  2. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 2 links have been added.
  3. Japan CSCL: Chemical Substances exempted from notification of manufacturing/import amount
      Confirmed link of CAS RN: 1 link has been deleted.
  4. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 3 links have been added.
  5. Japan: Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
      104 exemplified substances have been added and 1 exemplified substance has been deleted by reviewing the data.
  6. Japan ISHA: Newly Announced Chemical Substances
      Confirmed links of CAS RN: 3 links have been revised by reviewing the data.
  7. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      1 item (1 substance) has been added based on the notification of 2020/12/2 and 1 exemplified substance has been added by reviewing the data.
  8. TSCA: Significant New Use Rule (SNUR)
      30 rules have been added up to 2020/10/20 and 11/16 effectuation.
  9. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      Based on the notification issued on 2020/11/25, 8 substances have been added and ranges of application of 2 substances have been changed in Toxic substance(s).
  10. JSOH: Occupational Exposure Limits
      1 substance has been added and 1 substance has been revised based on the list of FY2020 publication.
  11. JSOH: Occupational Carcinogens
      2 substances have been added and 1 substance has been changed from 2B to 2A based on the list of FY2020 publication.
  12. IARC: Carcinogenicity Assessment
      1 agent has been added and 5 agents have changed on the list updated on 2020/10/27.
  13. Japan METI: Biodegradation and Bioconcentration Results
      The judgement results of Newly Announced Chemical Substances: 266 substances have been added. (published on 2020/09/28)
  14. General Information: Chemical Substance Name
      1418 substance names have been updated.
  15. General Information: Molecular formula, weight and SMILES
      993 molecular formula data and 872 SMILES data have been updated.
  16. General Information: Structure and Data for structure search
      Structures for 880 substances have been updated.
  17. Information of Japan Chemical Substance Dictionary (Nikkaji)
      2141 substances have been added.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

October 6, 2020 

Following data have been updated.
  1. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      Confirmed link of CAS RN: 56 links have been added.
  2. Japan CSCL: Chemical Substances exempted from notification of manufacturing/import amount
      Confirmed link of CAS RN: 17 links have been added.
  3. Japan: Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
      5,897 exemplified substances have been added by reviewing the data.
  4. Japan ISHA: Newly Announced Chemical Substances
      239 substances (2020/03/27 public notice) and 257 substances (2020/06/26 public notice) have been added.
      Confirmed links of CAS RN: 42 links have been revised (according to the MHLW website).
  5. EU: CLP Harmonised Classification
      37 substances have been added, 2 substances have been deleted and the entries of 21 substances have been replaced, based on the Official Journal of the European Union (ATP 15th) published on 2020/08/11.
  6. TSCA: Significant New Use Rule (SNUR)
      23 exemplified substances have been added up to 2020/09/25 effectuation.
      29 rules have been added up to 2020/08/10, 09/28 and 10/02 effectuation.
      1 rule has been removed up to 2020/09/24 effectuation.
  7. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      Based on the notification issued on 2020/07/27, 31 substances have been added and ranges of application of 7 substances have been changed in Toxic substance(s).
  8. International Chemical Safety Cards (ICSC)
      1 ICSC cards have been added based on 2020/7/21.
  9. Environmental Health Criteria (EHC)
      1 substance has been added based on the new publication(Vol.244)on 2020/04/12.
  10. US Agency for Toxic Substances and Disease Registry (ATSDR) Toxicological Profiles
      1 exemplified substance has been added based on the list of 2020/08/10 updated.
  11. JSOH: Occupational Exposure Limits
      4 substances have been added and 5 substances have been revised based on the list of FY2019 publication.
  12. JSOH: Occupational Carcinogens
      18 substances have been added , 1 substance has been deleted and 1 substance has been changed from 2B to 2A based on the list of FY2019 publication.
  13. JOSH: Occupational Sensitizers
      2 substances have been added based on the list of FY2019 publication.
  14. JSOH: Reproductive Toxicants
      1 substance has been added based on the list of FY2019 publication.
  15. EU: Carcinogenicity Assessment
      8 substances have been added and the carcinogenicity classification of 2 substances have been changed from 2 to 1B, based on the Official Journal of the European Union published on 2020/08/11.
  16. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN: 56 links have been added.
  17. General Information: Chemical Substance Name
      996 substance names have been updated.
  18. General Information: Molecular formula, weight and SMILES
      994 molecular formula data, 1 molecular weight data and 711 SMILES data have been updated.
  19. General Information: Structure and Data for structure search
      Structures for 712 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

July 31, 2020 

Following information has been added newly.
  1. Food Sanitation Act: Table 1 (1) in Appended table 1 of Specifications and Standards Notification; Base polymers (Plastics)
  2. Food Sanitation Act: Table 1 (2) in Appended table 1 of Specifications and Standards Notification; Base polymers (Coatings)
  3. Food Sanitation Act: Table 1 (3) in Appended table 1 of Specifications and Standards Notification; Base polymers (Trace amount monomer)
  4. Food Sanitation Act: Table 2 in Appended table 1 of Specifications and Standards Notification; Additives
Following data have been updated.
  1. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      226 Substances have been added based on the notification of 2020/7/31.
  2. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 1 link has been deleted.
  3. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 4 links have been added.
  4. Japan ISHA: Existing Chemical Substances
      Confirmed link of CAS RN:22 links have been revised by reviewing the data.
  5. Japan ISHA: Newly Announced Chemical Substances
      Confirmed links of CAS RN: 6 links have been revised by reviewing the data.
  6. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      1 exemplified substance has been deleted by reviewing the data.
  7. Japan: Poisonous and Deleterious Substances Control Act
      2 Poisonous Substances and 14 Deleterious Substances have been added and 1 exemplified substance (Deleterious Substances) has been deleted and 2 Cabinet Order Names have been modified based on the notification of 2020/06/24.
  8. Japan: Poisonous and Deleterious Substances Control Act: Substances excluded from Organic cyanide compounds
      2 substances have been added based on the notification of 2020/06/24.
  9. Japan: Act on Prohibition of Chemical Weapons and Control, etc. of Specific Chemicals (Chemical Weapons Prohibition Law)
      8 substances have been added and 8 exemplified substances have been added based on the notice on 2020/06/07.
  10. REACH: Substances of Very High Concern for Authorization (SVHC)
      4 substances have been added for Candidate List. (2020/6/25 announced)
  11. TSCA Inventory
      "ACTIVE" information has been added to 76 substances based on the list updated on 2020/06/01.
  12. TSCA: Significant New Use Rule (SNUR)
      11 rules have been added up to 2020/06/22 and 07/06 effectuation.
  13. GHS Classification Results by the Japanese Government
      164 classification results in 2019 have been added.
  14. ISHA: Examples of Occupational Accidents Caused by Chemical Substances
      7 substances have been added based on the list of 2020/6/30 updated.
  15. US Agency for Toxic Substances and Disease Registry (ATSDR) Toxicological Profiles
      1 exemplified substance has been added and 2 exemplified substances have been deleted based on the list of 2020/05/26 updated.
  16. Australia: Priority Existing Chemicals (PEC) Assessment Reports
      The link destination of 122 substances have been changed on the replacement (NICNA→AICIS) of 2020/07/01
  17. IARC: Carcinogenicity Assessment
      3 agents have been added and 4 agents have changed on the list updated on 2020/06/26.
  18. Safety Summary of Japan(JCIA BIGDr)
      13 substances have been added based on the list updated on June 12, 2020.
  19. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
      1 report has been added based on the announcement on 2020/06/15.
  20. General Information: Chemical Substance Name
      1038 substance names have been updated.
  21. General Information: Molecular formula, weight and SMILES
      1029 molecular formula data and 901 SMILES data have been updated.
  22. General Information: Structure and Data for structure search
      Structures for 922 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

June 2, 2020 

Following information has been added newly.
  1. TaiwanTCCSCA/OSHA: Existing Chemical Substances
Following data have been updated.
  1. Japan: Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
      2 exemplified substances have been added by reviewing the data.
  2. Japan ISHA: Newly Announced Chemical Substances
      One ISHA number and one chemical substance name have been revised based on the communication of MHLW (2020/4/10).
      Confirmed links of CAS RN: 2 links have been revised
  3. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      2 exemplified substances have been added by reviewing the data.
  4. Japan ISHA: Specified Chemical Substances
      2 Cabinet Order Names have been added based on the notification of 2020/04/22. 4 exemplified substances have been added by reviewing the data.
  5. Japan ISHA: Administrative Control Levels of Working Environment Evaluation Standards
      1 substance has been added based on the notification of 2020/04/22. 4 exemplified substances have been added by reviewing the data.
  6. Japan: Air Pollution Control Law
      By reviewing the data, 2 exemplified substances have been added.
  7. Japan: Water Pollution Control Law
      1 exemplified substance has been added by reviewing the data.
  8. TSCA: Significant New Use Rule (SNUR)
      11 rules have been added up to 2020/05/19 effectuation.
  9. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      Based on the notification issued on 2020/03/24, 13 substances have been added and ranges of application of 2 substances have been changed in Toxic substance(s).
  10. Korea: ARECs (K-REACH); Existing Chemical Substances
      Based on the notification issued on 2020/04/14, 15 substances have been added.
  11. Australia: Priority Existing Chemicals (PEC) Assessment Reports
      2 substances have been added based on the list updated of 2020/05/05.
  12. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
      1 report has been added based on the announcement on 2020/05/11.
  13. General Information: Chemical Substance Name
      93 substance names have been updated.
  14. General Information: Molecular formula, weight and SMILES
      78 molecular formula data, 1 molecular weight data and 58 SMILES data have been updated.
  15. General Information: Structure and Data for structure search
      Structures for 58 substances have been updated.
  16. Information of Japan Chemical Substance Dictionary (Nikkaji)
      2033 substances have been added.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

April 21, 2020 

Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      6 substances have been added based on the notification of 2020/04/01.
      3 substances have been deleted based on the notification of 2020/3/31.
      Confirmed link of CAS RN: 38 links have been added and 4 links have been deleted.
  2. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 1 link has been added.
  3. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 15 links have been added.
  4. Japan CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 5 links have been added and 2 links has been deleted.
  5. Japan CSCL: Type III Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 3 links have been added.
  6. Japan CSCL: Chemical Substances exempted from notification of manufacturing/import amount
      130 substances have been added based on the notification of 2020/03/31.
  7. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 24 links have been added and 1 link has been deleted.
  8. Japan ISHA: Newly Announced Chemical Substances
      172 substances have been added based on the notification of 2019/12/27.
  9. TSCA Inventory
      52 substances have been added, 2 names have been changed and "ACTIVE" information has been added to 122 substances based on the list updated on 2020/03/12.
  10. International Chemical Safety Cards (ICSC)
      4 substances have been added based on the list updated on 2020/03/26 and 8 ICSC titles have been changed by reviewing the data.
  11. IARC: Carcinogenicity Assessment
      Name of 1 agent has been changed and 8 exemplified substances have been deleted based on the list updated on 2020/03/03.
  12. Japan METI: Biodegradation and Bioconcentration Results
      Bioaccumulation test or Partition coefficient test:5 results have been deleted and 2 results have been revised. (published on 2019/09/06)
      Confirmed link of CAS RN:4 links have been added and 2 links have been deleted.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

March 17, 2020 

Following information has been added newly.
  1. MHLW: GHS Aligned Sample Label and SDS
Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      Confirmed link of CAS RN: 1 link has been added.
  2. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 1 link has been added.
  3. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 1 link has been deleted.
  4. Japan CSCL: Chemical Substances exempted from notification of manufacturing/import amount
      Confirmed link of CAS RN: 1 link has been added.
  5. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 1 link has been added.
  6. Japan: Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
      1 exemplified substance has been added by reviewing the data.
  7. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      1 exemplified substance has been added by reviewing the data.
  8. Japan ISHA: Specified Chemical Substances
      1 exemplified substance has been added by reviewing the data.
  9. Japan ISHA: Guidelines for Carcinogenicity Substances
      6 substances have been added based on the notifications of 2016/3/31 and 2020/2/7.
  10. Japan: Poisonous and Deleterious Substances Control Act
      1 exemplified substance (Poisonous Substances; 1) has been added, 2 exemplified substances (Poisonous Substances; 1, Deleterious Substances; 1) have been deleted and Law or Cabinet Order Name of 1 exemplified substance has been changed by reviewing the data.
  11. Japan: Air Pollution Control Law
      18 exemplified substances have been added by reviewing the data.
  12. Japan: Water Pollution Control Law
      3 exemplified substances have been added by reviewing the data.
  13. Japan: Soil Contamination Countermeasures Act
      2 exemplified substances have been added by reviewing the data.
  14. REACH: Substances of Very High Concern for Authorization (SVHC)
      11 substances have been added for Authorisation List of SVHCs. (Public announced on 2020/02/07)
  15. EU: CLP Harmonised Classification
      17 substances have been added, 2 substances have been deleted and the entries of 11 substances have been replaced, based on the Official Journal of the European Union published on 2020/02/18.
  16. TSCA: Significant New Use Rule (SNUR)
      61 rules have been added up to the last 2020/3/9 effectuation.
  17. IARC: Carcinogenicity Assessment
      Data of 9 agents have been changed on the list updated on 2020/02/18.
  18. EU: Carcinogenicity Assessment
      6 substances have been added and the carcinogenicity classification of 1 substance has been changed from 1B to 1A, based on the Official Journal of the European Union published on 2020/02/18.
  19. Safety Summary of Japan(JCIA BIGDr)
      15 substances have been added and names of 1 substance has been changed based on the list updated on January 20, 2020.
  20. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN: 1 link has been added.
  21. Japan ISHA: Carcinogenicity Test Results for Chemical Substances
      1 substance has been added based on the update of 2020/2/12.
  22. General Information: Chemical Substance Name
      1110 substance names have been updated.
  23. General Information: Molecular formula, weight and SMILES
      1060 molecular formula data and 429 SMILES data have been updated.
  24. General Information: Structure and Data for structure search
      Structures for 722 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

January 28, 2020 

Following information has been added newly.
  1. HS Code: Section VI "Products of the Chemical or Allied Industries"
Following data have been updated.
  1. Japan CSCL: Class I Specified Chemical Substances
      Confirmed link of CAS RN: 7 links have been added.
  2. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 3 links have been added.
  3. Japan CSCL: Chemical Substances exempted from notification of manufacturing/import amount
      Confirmed link of CAS RN: 80 links have been added.
  4. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      Confirmed link of CAS RN: 3 links have been added.
  5. Japan ISHA: Newly Announced Chemical Substances
      173 substances have been added based on the notification of 2019/9/27.
      7 substances have been deleted and 33 substances' name and/or other data have been corrected based on the notification of 2019/7/29.
  6. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      2 exemplified substances have been added.
  7. Japan ISHA: Strong Mutagenic Chemical Substances
      30 substances have been added in Notified Chemical Substances based on the notification issued on 2019/11/22 and 12/17.
  8. Japan: Air Pollution Control Law
      By reviewing the data, 1 exemplified substance has been added, and 1 exemplified substance has been deleted.
  9. Japan: Water Pollution Control Law
      1 exemplified substance has been added by reviewing the data.
  10. Rotterdam Convention on the Prior Informed Consent Procedure for Certain Hazardous Chemicals and Pesticides in International Trade (PIC)
      1 exemplified substance has been deleted by reviewing the data.
  11. REACH: Substances of Very High Concern for Authorization (SVHC)
      4 substances have been added for Candidate List. (2020/1/16)
  12. TSCA: Significant New Use Rule (SNUR)
      1 rule has been deleted and 51 rules have been added up to the last 2020/1/24 effectuation.
  13. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      Based on the notification issued on 2019/11/28, 8 substances have been added and 1 exemplified substance has been added in Toxic substance(s).
  14. US Agency for Toxic Substances and Disease Registry (ATSDR) Toxicological Profiles
      7 exemplified substances have been added based on the list of 2019/12/06 updated. 6 exemplified substances have been added by reviewing the data.
  15. IARC: Carcinogenicity Assessment
      4 substances have been added, 7 agents have been changed on the list updated on 2019/12/12.
  16. ICCA Safety Summary of Japan(JCIA BIGDr)
      36 substances have been added, names of 45 substances have been changed and 10 substances have been deleted based on the list updated on August 23, 2019.
  17. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN: 1 link has been added.
  18. General Information: Chemical Substance Name
      2085 substance names have been updated.
  19. General Information: Molecular formula, weight and SMILES
      1068 molecular formula data and 7890 SMILES data have been updated.
  20. General Information: Structure and Data for structure search
      Structures for 1094 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

November 27, 2019 

In the October 8, 2019 update, 20 exemplified substances were incorrectly added to Japan ISHA: Lead, etc. / Tetraalkyl lead, etc. In this update, these substances are deleted.

November 26, 2019 

Following data have been updated.
  1. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 10 links have been added.
  2. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      1 substance has been added.
  3. Japan: Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
      1 exemplified substance has been deleted by reviewing the data.
  4. Japan ISHA: Newly Announced Chemical Substances
      Confirmed links of CAS RN: 1 link has been revised.
  5. UN Number and UN Hazard Class
      4 UN Numbers have been added and 3 names have been changed, based on the Dangerous Goods List of Rev. 21 (2019).
  6. TSCA Inventory
      31 substances have been added, 3 names have been changed and "ACTIVE" information has been added to 270 substances based on the list updated on 2019/9/20.
  7. TSCA: Significant New Use Rule (SNUR)
      80 rules have been added up to 2019/11/18 effectuation.
  8. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      Based on the notification issued on 2019/10/15, 18 substances have been added, names of 2 substances have been changed and 32 exemplified substances have been added in Toxic substance(s).
  9. Environmental Health Criteria (EHC)
      1 exemplified substance has been deleted by reviewing the data.
  10. Japan METI: Biodegradation and Bioconcentration Results
      The judgement results of Newly Announced Chemical Substances: 210 substances have been added. (published on 2019/10/28)
  11. Japan MHLW: Toxicity Test Results
      14 substances have been added based on the list updated on November 2018.
  12. Japan MOE: Results of Eco-toxicity tests of chemicals
      5 substances have been added based on the data of 2018/3 and 2019/3 publication.
  13. General Information: Chemical Substance Name
      2523 substance names have been updated.
  14. General Information: Molecular formula, weight and SMILES
      974 molecular formula data have been updated.
  15. General Information: Structure and Data for structure search
      Structures for 705 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

October 8, 2019 

Following information has been added newly.
  1. US EPA: Acute Exposure Guideline Levels (AEGLs)
Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      Confirmed link of CAS RN: 1 link has been added.
  2. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 1 link has been deleted.
  3. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 4 links have been added and 17 links have been deleted.
  4. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      50 substances have been added.
  5. Japan: Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
      132 exemplified substances have been added by reviewing the data.
  6. Japan: Poisonous and Deleterious Substances Control Act
      875 exemplified substances have been added by reviewing the data.
  7. Japan: Poisonous and Deleterious Substances Control Act: Substances excluded from Organic cyanide compounds
      2 exemplified substances have been added by reviewing the data.
  8. Japan ISHA: Newly Announced Chemical Substances
      194 substances have been added based on the notification of 2019/6/27.
      Confirmed links of CAS RN: 1 link has been revised.
  9. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      83 exemplified substances have been added by reviewing the data.
  10. Japan ISHA: Specified Chemical Substances
      26 exemplified substances have been added by reviewing the data.
  11. Japan ISHA: Lead, etc. / Tetraalkyl lead, etc
      20 exemplified substances have been added by reviewing the data.
  12. Japan ISHA: Dangerous Substances
      4 exemplified substances have been added by reviewing the data.
  13. Japan ISHA: Administrative Control Levels of Working Environment Evaluation Standards
      46 exemplified substances have been added by reviewing the data.
  14. Japan: Air Pollution Control Law
      202 exemplified substances have been added by reviewing the data.
  15. Japan: Water Pollution Control Law
      176 exemplified substances have been added by reviewing the data.
  16. Japan: Soil Contamination Countermeasures Act
      123 exemplified substances have been added by reviewing the data.
  17. Stockholm Convention on Persistent Organic Pollutants (POPs)
      9 exemplified substances have been added by reviewing the data.
  18. Rotterdam Convention on the Prior Informed Consent Procedure for Certain Hazardous Chemicals and Pesticides in International Trade (PIC)
      2 substances have been added based on the notification of the official announcement (Effective 2019/09/16).
  19. REACH: Substances of Very High Concern for Authorization (SVHC)
      2 exemplified substances have been deleted on Candidate List of SVHCs.
  20. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      Toxic Substance(s) (15 substances) have been added based on the notification issued on 2019/9/10.
  21. ISHA: Risk Assessment Report
      9 substances have been added based on the update of 2019/8/23.
  22. ISHA: Examples of Occupational Accidents Caused by Chemical Substances
      8 substances have been added based on the list of 2019/7/24 updated.
  23. US EPA: Integrated Risk Information System (IRIS)
      15 substances have been deleted based on List by Archived updated on 2019/02/18.
  24. IARC: Carcinogenicity Assessment
      Data of 3 agents have been changed on the list updated on 2019/7/16.
  25. Japan METI: Biodegradation and Bioconcentration Results
      The judgement results of Newly Announced Chemical Substances: 3712 substances have been added. (publiced on 2019/09/06)
      Bioaccumulation test or Partition coefficient test:1373 result have been added. (publiced on 2019/09/06)
  26. Japan ISHA: Carcinogenicity Test Results for Chemical Substances
      1 substance has been added based on the update of 2019/8/23.
  27. General Information: Chemical Substance Name
      1098 substance names have been updated.
  28. General Information: Molecular formula, weight and SMILES
      83 molecular formula data and 6 SMILES data have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

July 31, 2019 

Following information has been added newly.
  1. Taiwan: TCCSCA; Existing Chemical Substances Subject to Standard Registration
Following data have been updated.
  1. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      210 Substances have been added based on the notification of 2019/7/31.
  2. Japan CSCL: Existing Chemical Substances
      Confirmed links of CAS RN: 1 link has been added.
  3. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      1 substance has been added.
  4. Japan: Poisonous and Deleterious Substances Control Act
      8 substances have been added and 3 Cabinet Order Names have been modified in Deleterious Substances based on the notification of 2019/6/19.
      1 exemplified substance has been added in Deleterious Substances by reviewing the data.
  5. Japan: Poisonous and Deleterious Substances Control Act: Substances excluded from Organic cyanide compounds
      1 substance has been added based on the notification of 2019/6/19.
  6. Japan ISHA: Newly Announced Chemical Substances
      198 substances have been added based on the notification of 2019/3/27.
  7. Japan ISHA: Strong Mutagenic Chemical Substances
      2 substances have been added and 1 substance has been deleted in Existing Chemical Substances based on the notification issued on 2019/6/25.
  8. REACH: Substances of Very High Concern for Authorization (SVHC)
      4 substances have been added for Candidate List based on the notification of 2019/7/16.
  9. EU: CLP Harmonised Classification
      2 substances have been deleted by reviewing the data.
  10. TSCA: Significant New Use Rule (SNUR)
      1 rule (7 substances) has been added up to 2019/6/24 effectuation.
  11. TSCA: Regulation of hazardous chemical substances and mixtures
      6 exemplified substances have been added by reviewing the data.
  12. Taiwan: TCCSCA; Toxic Chemicals
      The name of the law has been changed to the Toxic and Concerned Chemical Substances Control Act (TCCSCA).
  13. GHS Classification Results by the Japanese Government
      292 classification results in 2019 have been added.   
  14. IARC: Carcinogenicity Assessment
      1 substance name has been changed and 1 exemplified substance has been deleted on the list updated on 2019/7/16.
  15. General Information: Chemical Substance Name
      3256 substance names has been updated.
  16. General Information: Molecular formula, weight and SMILES
      999 molecular formula data have been updated.
  17. General Information: Structure and Data for structure search
      Structures for 854 substances have been updated.
  18. Information of Japan Chemical Substance Dictionary (Nikkaji)
      3531 substances have been added, 20 substances have been deleted.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

June 4, 2019 

Following data have been updated.
  1. General Information: Chemical Substance Name
      2345 substance name has been updated.
  2. General Information: Molecular formula, weight and SMILES
      1017 molecular formula data have been updated.
  3. General Information: Structure and Data for structure search
      Structures for 619 substances have been updated.
  4. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 1 link has been added
  5. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      1 exemplified substance has been added.
  6. TSCA: Regulation of hazardous chemical substances and mixtures
      1 substance has been added up to 2019/5/28 effectuation.
  7. TSCA: Significant New Use Rule (SNUR)
      12 rules have been added up to 2019/6/4 effectuation.
  8. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      Toxic Substance(s) (38 substances) have been added based on the notification issued on 2019/4/19.
  9. Korea: ARECs (K-REACH); Existing Chemical Substances
      3 substances have been added, 5 substances have been deleted and names of 301 substances have been changed based on the notification issued on 2019/5/8.
  10. Korea: ARECs (K-REACH); Others
      Annex I of "Chemical substances exempted from registration or notification" and 1 exemplified substance in "Phase-in substance(s) subject to registration" have been added."
  11. US Agency for Toxic Substances and Disease Registry (ATSDR) Toxicological Profiles
      1 substance has been added based on the list of 2019/4/19 updated.
  12. Australia: Priority Existing Chemicals (PEC) Assessment Reports
      1 substance has been added based on the list updated of 2019/05/07.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

April 16, 2019 

Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      15 substances have been added based on the notification of 2019/4/1.
       Confirmed link of CAS RN: 85 links have been added and 1 link has been deleted.
  2. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 1 link has been added.
  3. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      Confirmed link of CAS RN: 1 link has been added.
  4. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 5 links have been added and 5 links have been deleted.
  5. Japan CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 2 links have been added and 1 link has been deleted.
  6. Japan CSCL: Type III Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 1 link has been added.
  7. Japan CSCL: Chemical Substances exempted from notification of manufacturing/import amount
      150 substances have been added based on the notification of 2019/3/29.
  8. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      9 substances have been added and 2 sbstances have been deleted.
  9. Japan: Soil Contamination Countermeasures Act
      One Cabinet Order Name has been changed and 2 substances have been added on the based on the notification of 2018/9/28.
  10. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN: 2 links have been added.
  11. General Information: Chemical Substance Name
      1 substance name has been updated.
  12. General Information: Structure and Data for structure search
      Structure for 1 substance has been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF].

March 19, 2019  
NITE-CHRIP has been renewed. The main changes are as follows.
  1. "Outline" and "Related material" of each Law and Regulation, etc. are available on the "Lists of Laws and Regulations, etc." page.
  2. Search results pages are directly linked to the "Lists of Laws and Regulations, etc." page.
  3. Search Tool of drawing a structural formula is available (Seach Options).
Following information has been added newly.
  1. Korea: ARECs (K-REACH); Existing Chemical Substances
       Existing Chemical Substances (Domestically distributed commercial purpose before 2 February, 1991.)(37090 substances) and Existing Chemical Substances (Has undergone hazard review after 2 February, 1991.) (7390 substances) based on the notification issued on 2019/1/28 are included.
  2. Korea: ARECs (K-REACH); Others
      CMR Substances(364 substances) and Chemical Substances Exempted from Registration or Notification(44 substances) based on the notification issued on 2018/12/28, and Phase-in substances subject to registration(510 substances) are included.
Following information (only "Outline of the Regulation" and "Related Material") has been added newly.
  1. Fire Service Act
  2. Foreign Exchange and Foreign Trade Act
  3. High Pressure Gas Safety Act
Following data have been updated.
  1. Japan: Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
      1 exemplified substance has been added.
  2. Japan ISHA: Newly Announced Chemical Substances
      208 substances have been added based on the notification of 2018/12/27.
      Confirmed links of CAS RN: 5 links have been revised.
  3. Japan ISHA: Strong Mutagenic Chemical Substances
      1 substance has been deleted by reviewing the data.
  4. UN Number and UN Hazard Class
      28 exemplified substances have been added by reviewing the data.
  5. TSCA Inventory
      57 substances have been added, 6 names have been changed and "ACTIVE" information has been added to 1,870 substances based on the list updated on 2019/2/19.
  6. Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances
      Priority Control Substances (672 substances) have been added newly based on the notification issued on 2018/12/28.
      1 substance has been added in Toxic substance(s) by reviewing the data.
  7. IARC: Carcinogenicity Assessment
      Group of 1 substance has been changed, based on the list updated on 2019/2/22.
  8. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
      1 draft has been revised to the final report supdated on 2019/02/28.
  9. General Information: Chemical Substance Name
      1232 substance names have been updated.
  10. General Information: Molecular formula, weight and SMILES
      1221 molecular formula data and 37039 SMILES data have been updated.
  11. General Information: Structure and Data for structure search
      Structures for 772 substances have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF 62 KB].

February 5, 2019 

Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      Confirmed link of CAS RN: 3 links have been added.
  2. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      Confirmed link of CAS RN: 2 links have been added.
  3. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 11 links have been added.
  4. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 64 links have been added and 1 link has been deleted.
  5. Japan CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 1 link has been added.
  6. Japan CSCL: Type III Monitoring Chemical Substances (before amendment)
      Confirmed link of CAS RN: 1 link has been added.
  7. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      11 substances have been added.
  8. Japan: Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
      2 exemplified substances have been added.
  9. Japan: Poisonous and Deleterious Substances Control Act
      4 substances have been added (Deleterious Substances) based on the notification of 2018/12/19.
  10. Japan: Poisonous and Deleterious Substances Control Act: Substances excluded from Organic cyanide compounds
      1 substance has been added based on the notification of 2018/12/19.
  11. Japan ISHA: Existing Chemical Substances
      English names (serial number 18001-20298) have been added.
      Confirmed links of CAS RN: 3 links have been deleted.
  12. Japan ISHA: Newly Announced Chemical Substances
      246 substances have been added based on the notification of 2018/9/27.
      Confirmed links of CAS RN: 18 links have been revised.
  13. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc
      2 exemplified substances have been added.
  14. Japan ISHA: Specified Chemical Substances
      2 exemplified substances have been added.
  15. Japan ISHA: Administrative Control Levels of Working Environment Evaluation Standards
      2 exemplified substances have been added.
  16. Japan ISHA: Strong Mutagenic Chemical Substances
      1 substance has been added in Existing Chemical Substances and 28 substances have been added in Notified Chemical Substances (2018/12/05).
      3 substances have been deleted by reviewing the data.
  17. Stockholm Convention on Persistent Organic Pollutants (POPs)
      2 substances have been added in Annex A and 1 substance has been added in Annex C. (Effective 2018/12/18)
  18. REACH: Substances of Very High Concern for Authorization (SVHC)
      6 substances have been added for Candidate List. (2019/1/15)
  19. Korea: Act on the Registration and Evaluation, etc. of Chemical Substances (ARECs) / Chemicals Control Act (CCA)
      Based on the notification issued on 2018/12/19, 8 substances (9 exemplified substances) have been added to Toxic Substance(s).
      8 exemplified substances have been added and 5 exemplified substances have been deleted in Toxic substance(s) by reviewing the data.2
  20. US EPA: Integrated Risk Information System (IRIS)
      6 substances have been added based on the list updated on 2018/12/27. 14 substances have been been deleted by archived.
  21. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN: 4 links have been added.
  22. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
      2 drafts have been revised to the final reports based on the list updated on 2018/10/15.
  23. General Information: Chemical Substance Name
      1409 substance names have been updated.
  24. General Information: Molecular weight and formula
      1404 molecular formula data have been updated.
  25. General Information: Structure and Data for structure search
      Structures for 992 substances have been updated.
      879 Data for structure search have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF 48 KB].

December 4, 2018 

Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      Confirmed link of CAS RN: 1 link has been added.
  2. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed link of CAS RN: 1 link has been added and 2 links have been deleted.
  3. Japan CSCL: Existing Chemical Substances
      Confirmed link of CAS RN: 2 links have been added and 2 links have been deleted.
  4. Japan: Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
      1 exemplified substance has been added.
  5. Japan ISHA: Existing Chemical Substances
      English names (serial number 16001-18000) have been added.
  6. EU: CLP Harmonised Classification
      16 substances have been added, 1 substance has been deleted and the entries of 18 substances have been replaced, based on the Official Journal of the European Union (ATP 13th) published on October 5, 2018.
  7. Korea: Act on the Registration and Evaluation, etc. of Chemical Substances (ARECs) / Chemicals Control Act (CCA)
      Based on the notification issued on October 12, 2018, 15 substances have been added and Range of Application of 1 substance has been changed in Toxic substance(s).
  8. Relational Information System for Chemical Accidents Database(RISCAD)
      153 accident information have been added.
      4 substances have been added.
  9. JSOH: Occupational Exposure Limits
      3 substances have been added and 6 substances have been revised based on the list of FY2018 publication.
  10. JSOH: Occupational Carcinogens
      9 substances have been added and 6 substances have been revised based on the list of FY2018 publication.
  11. JOSH: Occupational Sensitizers
      1 substance has been added and 5 substances have been revised based on the list of FY2018 publication.
  12. JSOH: Reproductive Toxicants
      3 substances have been added and 2 substances have been revised based on the list of FY2018 publication.
  13. IARC: Carcinogenicity Assessment
      9 substances have been added, and 1 substance has been deleted, based on the list updated on November 9, 2018.
  14. EU: Carcinogenicity Assessment
      6 substances have been added and a category of 1 substance has been changed from 2 to 1B, based on the Official Journal of the European Union (ATP 13th) published on October 5, 2018.
  15. ICCA Safety Summary of Japan(JCIA BIGDr)
      2 substances have been added based on the list updated on October 11, 2018.
  16. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS RN: 2 links have been added.
  17. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
      1 draft has been revised to the final report based on the list updated on August 31, 2018.
  18. General Information: Chemical Substance Name
      1560 substance names have been updated.
  19. General Information: Structure and Data for structure search
      Structures for 1185 substances have been updated.
      1052 Data for structure search have been updated.     
  20. General Information: Molecular weight and formula
      1553 molecular formula data have been updated.
  21. Information of Japan Chemical Substance Dictionary (Nikkaji)
      7340 substances have been added, 28 substances have been revised, 3 substances have been deleted.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF 42 KB].

October 10, 2018 

Following data have been updated.
  1. Japan CSCL: Class I Specified Chemical Substances
      Confirmed link of CAS RN: 1 link has been added.
  2. Japan CSCL: Priority Assessment Chemical Substances
      Confirmed links of CAS RN: 5 links have been added and 2 links have been deleted.
  3. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed links of CAS RN: 2 links have been added and 1 link has been deleted.
  4. Japan CSCL: Existing Chemical Substances
      Confirmed links of CAS RN: 6 links have been added and 7 links have been deleted.
  5. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      Confirmed links of CAS RN: 39 links have been added.
  6. Japan CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed links of CAS RN: 1 link has been added and 2 links have been deleted.
  7. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      7 substances have been added.
  8. Japan ISHA: Existing Chemical Substances
      English names (serial number 14001-16000) have been added.
      Confirmed links of CAS RN: 1 link has been deleted.
  9. Japan ISHA: Newly Announced Chemical Substances
      201 substances have been added based on the notification of 2018/6/27.
      Confirmed links of CAS RN: 1 link has been added and 1 link has been revised and 2 links have been deleted.
  10. Japan: Act on the Protection of the Ozone Layer through the Control and Other Measures on Specified Substances and Other Substances
      18 substances have been added as alternatives to specified substances.
  11. Korea: Act on the Registration and Evaluation, etc. of Chemical Substances (ARECs) / Chemicals Control Act (CCA)
      Based on the notification issued on 2018/8/24, 1 substance has been added to Restricted Substance(s). 1 substance has been added and 4 substances have been deleted in Toxic substance(s) by reviewing the data.
  12. US Agency for Toxic Substances and Disease Registry (ATSDR) Toxicological Profiles
      2 substances have been added based on the list of 2018/8/14 updated.
  13. US EPA: Integrated Risk Information System (IRIS)
      2 substances have been added by reviewing the data.
  14. ICCA Safety Summary of Japan(JCIA BIGDr)
      3 substances have been added based on the list updated on August 13, 2018.
  15. Japan METI: Biodegradation and Bioconcentration Results
      The judgement results of Newly Announced Chemical Substances (given public notice on 2018/7/31): 257 substances have been added.
  16. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
      1 draft has been revised to full report based on the list updated on 2018/8/31.
  17. General Information: Chemical Substance Name
      1873 substance names have been updated.
  18. General Information: Structure and Data for structure search
      Structures for 1548 substances have been updated.
      1455 Data for structure search have been updated.     
  19. General Information: Molecular weight and formula
      1865 molecular formula data have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF 54 KB].

July 31, 2018  

Following data have been updated.
  1. Class I Specified Chemical Substances
      Confirmed links of CAS RN: 19 links have been added.
  2. Japan CSCL: Priority Assessment Chemical Substances
      Confirmed links of CAS RN: 269 links have been added.
  3. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      257 Substances have been added based on the notification of 2018/7/31.
  4. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed links of CAS RN: 2 links have been added.
  5. Japan CSCL: Existing Chemical Substances
      Confirmed links of CAS RN: 6 links have been added and 3 links have been deleted.
  6. Japan CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed links of CAS RN: 17 links have been added.
  7. Japan CSCL: Type III Monitoring Chemical Substances (before amendment)
      Confirmed links of CAS RN: 9 links have been added.
  8. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      1 substance has been added.
  9. Japan: Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
      1 exemplified substance has been added and 1 exemplified substance has been deleted.
  10. Poisonous and Deleterious Substances Control Act
      18 substances have been added (Poisonous Substances : 7, Deleterious Substances : 11) and 2 Cabinet Order Names have been modified based on the notification of 2018/6/29.
      CAS registry numbers of 2 Deleterious Substances have been added by reviewing the data.
  11. Poisonous and Deleterious Substances Control Act: Substances excluded from Organic cyanide compounds
      3 substances have been added based on the notification of 2018/6/29.
  12. Japan ISHA: Existing Chemical Substances
      English names (serial number 10001-12000) have been added.
      Confirmed links of CAS RN: 1 link has been added.
  13. Japan ISHA: Newly Announced Chemical Substances
      Confirmed links of CAS RN: 3 link has been added.
  14. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc.
      The information before the enforcement on 2018/7/1 has been deleted.
  15. REACH: Substances of Very High Concern for Authorization (SVHC)
      10 substances have been added to Candidate List. (2018/06/27)
  16. Korea: Act on the Registration and Evaluation, etc. of Chemical Substances (ARECs) / Chemicals Control Act (CCA)
      Based on the notification issued on 2018/6/29, 13 substances have been added to Toxic substance(s). 1052 substances have been added by reviewing the data (Toxic substance(s) : 989, Restricted Substance(s) : 35, Prohibited Substance(s) : 21, Accident Precaution Chemical : 1, Phase-in substance(s) subject to registration : 6).
  17. IARC: Carcinogenicity Assessment
      3 substances have been added, 1 substance has been deleted and Group of 2 substances have been changed based on the list updated on 2018/6/29.
  18. General Information: Chemical Substance Name
      836 substance names have been updated.
  19. General Information: Structure and Data for structure search
      Structures for 566 substances have been updated.
      540 Data for structure search have been updated.     
  20. General Information: Molecular weight and formula
      797 molecular formula data have been updated.
*Announcement on the Chemical Substances Control Law Data
In addition to the combination of (1) and (2) previously published, we started posting about the combination (3) newly from this time. For details, please refer to page 9 of the manual. For (3), please be sure to check the condition that the substance of CAS number matches the substance indicated by MITI number.

(1)When the substance of CAS number exactly matches the substance indicated by MITI number
(2)When the substances of CAS number is included in the substance indicated by MITI number
(3)When the substance of CAS number matches the substance indicated by MITI number when a certain condition is fulfilled(The condition is listed in the remarks column of the search results)

Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF 64 KB].

 June 5, 2018

Following data have been updated.
  1. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      Confirmed links of CAS RN: 1 link has been added.
  2. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      1 substance has been added and 1 substance has been deleted.
  3. Japan: Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
      2 exemplified substances have been added.
  4. Japan ISHA: Existing Announced Chemical Substances
      English names (serial number 10001-12000) have been added.
  5. Japan ISHA: Newly Announced Chemical Substances
      264 substances have been added based on the notification of 2018/3/27.
      Confirmed links of CAS RN: 2 links have been added and 2 links have been revised.
  6. Japan ISHA: Chemical Substances prohibited from Manufacturing, etc.
      1 substance's name has been changed based on the notification of 2018/4/6.
  7. Japan ISHA: Chemical Substances requiring permission of Manufacture, etc.
      1 substance has been added based on the notification of 2018/4/6.
      1 exemplified substance has been added by reviewing the data.
  8. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc.
      2 substances have been added based on the notification of 2018/4/6.
      34 exemplified substances have been added by reviewing the data.
  9. Japan ISHA: Specified Chemical Substances
      9 exemplified substances have been added.
  10. Japan ISHA: Lead, etc. / Tetraalkyl lead, etc
      1 exemplified substance has been added.
  11. Japan ISHA: Administrative Control Levels of Working Environment Evaluation Standards
      9 exemplified substances have been added.
  12. Japan ISHA: Strong Mutagenic Chemical Substances
      CAS RN of 1 substance has been deleted by reviewing the data.
  13. Japan Poisonous and Deleterious Substances Control Act
      17 exemplified substances have been added.
  14. Air Pollution Control Law
      19 exemplified substances have been added.
  15. Water Pollution Control Law
      21 exemplified substances have been added.
  16. Soil Contamination Countermeasures Act
      10 exemplified substances have been added.
  17. EC Inventory
      EC Name and Data Description have been updated by the EC inventory updated on 2017/8/11.
  18. EU: CLP Harmonised Classification
      2 substances have been added and Hazard Class of 1 substance has been changed, based on the Official Journal of the European Union publised on 2018/5/4.
  19. TSCA Inventory
      176 substances have been added, 1 substance has been deleted, 6 names have been changed and "ACTIVE" information has been added to 20937 substances based on the list updated on 2018/4/12.
  20. Korea: Act on the Registration and Evaluation, etc. of Chemical Substances (ARECs) / Chemicals Control Act (CCA)
      9 substances have been added, the number of 22 substances have been changed and the names of 3 substances have been changed in Toxic Substance(s) based on the notification of 2018/3/30 and 2018/4/2.
      10 substances have been deleted by reviewing the data in Toxic Substance(s).                                         
  21. GHS Classification Results by the Japanese Government
      151 classification results in 2017 have been added.                                                 
  22. Relational Information System for Chemical Accidents Database(RISCAD)
      163 accident information has been added.
      1 substance has been added.
  23. ISHA: Risk Assessment Report
      7 substances have been added based on the update of 2018/4/20.
  24. ISHA: Examples of Occupational Accidents Caused by Chemical Substances
      1 substance has been added based on the list of 2018/5/7 updated.
  25. US Agency for Toxic Substances and Disease Registry (ATSDR): Toxicological Profiles
      1 substance has been deleted based on the list of 2018/4/9 updated.
  26. Canada: Priority Substances List (PSL)
      29 exemplified substances have been added and 2 exemplified substances have been deleted by reviewing the data.
  27. IARC: Carcinogenicity Assessment
      1 substance has been added and Group of 1 substance has been changed.     
  28. EU: Carcinogenicity Assessment
      Category of 1 substance has been changed based on the Official Journal of the European Union publised on 2018/5/4.
  29. ICCA Safety Summary of Japan(JCIA BIGDr)
      36 substances have been added and 3 substances have been deleted based on the list updated on March 12, 2018.
  30. Japan METI: Biodegradation and Bioconcentration Results
      The judgement and test result of degradation products of new chemical substances(judged from 1974 to 1993) : 23 substances have been added.
  31. General Information: Chemical Substance Name
      1627 substance names have been updated.
  32. General Information: Structure and Data for structure search
      Structures for 1001 substances have been updated.
      951 Data for structure search have been updated.     
  33. General Information: Molecular weight and formula
      1605 molecular formula data have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF 58 KB].

 April 17, 2018

Following data have been updated.
  1. Japan CSCL: Class I Specified Chemical Substances
      2 substances have been added based on the notifications of 2018/2/21.
  2. Japan CSCL: Monitoring Chemical Substances
      2 substances have been added and 1 substance has been deleted based on the notification of 2018/4/2.
  3. Japan CSCL: Priority Assessment Chemical Substances
      9 substances have been added based on the notification of 2018/4/2.
      2 substances have been deleted based on the notification of 2018/3/30.
  4. Japan CSCL: Existing Chemical Substances
      Confirmed links of CAS Registry Number : 2 links have been added.
  5. Japan CSCL: Chemical Substances exempted from notification of manufacturing/import amount
      143 substances have been added based on the notifications of 2018/3/30.
  6. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      2 substances have been added and 1 substance has been deleted.
  7. Japan Air Pollution Control Law
      "Mercury and its compounds" has been added based on the notification of 2016/9/26.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF 19 KB].

 March 20, 2018

Following information has been added newly.
  1. TaiwanTCSCA: Toxic Chemicals
  2. Relational Information System for Chemical Accidents Database(RISCAD)
  3. Japan ISHA: Guidelines for Carcinogenicity Substances
  4. ISHA: Risk Assessment Report
  5. ISHA: Examples of Occupational Accidents Caused by Chemical Substances
  6. ISHA: Carcinogenicity Test Results for Chemical Substances
  7. Poisonous and Deleterious Substances Control Act: Substances excluded from Organic cyanide compounds
Following data have been updated.
  1. Japan CSCL: Priority Assessment Chemical Substances
      Confirmed links of CAS Registry Number : 82 links have been added.
  2. Japan CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      Confirmed links of CAS Registry Number : 2 links have been added.
  3. Japan CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed links of CAS Registry Number : 6 links have been added and 1 link has been deleted.
  4. Japan CSCL: Existing Chemical Substances
      Confirmed links of CAS Registry Number : 7 links have been added and 2 link has been deleted.
  5. Japan CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed links of CAS Registry Number : 1 link has been added.
  6. Japan CSCL: Chemical Substances not regarded as a New Chemical Substances
      49 substances have been added.
  7. Japan: Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
      11 exemplified substances have been added.
  8. Japan ISHA: Existing Chemical Substances
      English names (serial number 8001-10000) have been added.
      Confirmed links of CSCL Number : 3 links have been added.
  9. Japan ISHA: Newly Announced Chemical Substances
      192 substances have been added as Newly Announced Chemical Substances. (Public Notice 2017/12/27).
      Confirmed links of CSCL Number : 5 links have been added.
  10. Japan ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc.
      11 exemplified substances have been added.
  11. Japan ISHA: Specified Chemical Substances
      11 exemplified substances have been added.
  12. Japan ISHA: Administrative Control Levels of Working Environment Evaluation Standards
      11 exemplified substances have been added.
  13. Japan Poisonous and Deleterious Substances Control Act
      11 exemplified substances have been added.
  14. Japan Act on the Protection of the Ozone Layer through the Control of Specified Substances and Other Measures
      2 exemplified substances have been added.
  15. Japan Air Pollution Control Law
      11 exemplified substances have been added.
  16. Japan Water Pollution Control Law
      11 exemplified substances have been added.
  17. Japan Soil Contamination Countermeasures Act
      11 exemplified substances have been added.
  18. The ASEAN-Japan Chemical Safety Database (AJCSD): Laws and Regulations
      22 substances have been added because of update of AJCSD.
  19. AJCSD: GHS Classification Results / Sample SDS
      23 substances have been added because GHS Classification Results by the Myanmar Government have been added to AJCSD.
  20. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
      2 drafts have been added and 1 draft has been revised to full report based on the list of February 6, 2018 updated.
  21. General Information: Chemical Substance Name
      1648 substance names have been updated.
  22. General Information: Structure and Data for structure search
      Structures for 1425 substances have been updated.
      1415 Data for structure search have been updated.
  23. Molecular weight and formula
      1563 molecular formula data have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF 50 KB].

Following content has been updated.
    FAQ
 January 30, 2018

Following data have been updated.
  1. Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
      590 exemplified substances have been added.
      The information of "Examples of metal compounds" in the Remarks column in the Search Results screen has been moved to the Data Description screen.
  2. ISHA: Existing Chemical Substances
      English names (serial number 6001-8000) have been added.
      1 ISHA number has been revised.
  3. ISHA: Newly Announced Chemical Substances
      267 substances have been added as Newly Announced Chemical Substances. (Public Notice 2017/9/27).
      Confirmed links of CAS Registry Number : 4 links have been revised.
  4. ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc.
      165 exemplified substances have been added and 8 exemplified substances have been revised.
  5. ISHA: Specified Chemical Substances
      6 exemplified substances of chromic acid and its salts have been deleted by reviewing the data.
  6. ISHA: Administrative Control Levels of Working Environment Evaluation Standards
      6 exemplified substances of chromic acid and its salts have been deleted by reviewing the data.
  7. ISHA: Strong Mutagenic Chemical Substances
      6 substances have been added in Existing Chemical Substances and 32 substances have been added in Notified Chemical Substances (2017/11/21).
  8. REACH: Substances of Very High Concern for Authorization (SVHC)
      7 substances have been added for Candidate List. (2018/01/15)
  9. TSCA: Significant New Use Rule (SNUR)
      59 rules have been added up to 2017/12/18 effectuation.
  10. Korea: Act on the Registration and Evaluation, etc. of Chemical Substances (ARECs) / Chemicals Control Act (CCA)
      22 substances of Toxic Substance(s) have been added based on the notification of 2018/1/5.
  11. Japan METI: Biodegradation and Bioconcentration Results
      1 substance has been added.
  12. Japan MHLW: Toxicity Test Results
      9 substances have been added based on the list updated on November 2017.
  13. Japan MOE: Results of Eco-toxicity tests of chemicals
      2 substances have been added based on the data of 2017/3 publication and by reviewing the data.
  14. General Information: Chemical Substance Name
      3420 substance names have been updated.
  15. General Information: Structure and Data for structure search
      Structures for 2299 substances have been updated.
      2289 Data for structure search have been updated.
  16. Molecular weight and formula
      3058 molecular formula data have been updated.
Regarding Chemical Substances that have been added, revised or deleted, please refer to the attachment[PDF markPDF 80 KB].

 November 28, 2017

Following information has been added newly.
    EU: CLP Harmonised Classification
Following data have been updated.
  1. CSCL: Priority Assessment Chemical Substances
      Confirmed links of CAS Registry Number : 3 links have been added.
  2. CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      Confirmed links of CAS Registry Number : 33 links have been added.
  3. CSCL: Existing Chemical Substances
      Confirmed links of CAS Registry Number : 11 links have been added and 7 links have been deleted.
  4. CSCL: Chemical Substances exempted from notification of manufacturing/import amount
      6 substances have been added.
  5. Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
      1 exemplified substance has been added.
  6. ISHA: Existing Chemical Substances
      English names (serial number 4001-6000) have been added.
      Confirmed links of CAS Registry Number : 1 link has been deleted.
      2 ISHA numbers have been revised.
  7. ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc.
      2 exemplified substances have been added.
  8. Poisonous and Deleterious Substances Control Act
      210 exemplified substances have been added and 1 exemplified substance has been deleted.
  9. Water Pollution Control Law
      1 exemplified substance has been added.
  10. UN Number and UN Hazard Class
      15 UN Numbers have been added and 1 substance name has been revised, based on the Dangerous Goods List of Rev.20 (2017) and by reviewing the data.
  11. TSCA: Significant New Use Rule (SNUR)
      1 rule has been added up to 2017/11/2 effectuation.
  12. GHS Classification Results by the Japanese Government
      For substances for which several classification results of different years are available and one result of which is displayed with "latest" but limited to part of hazard classes, a supplemental explanation of how to refer the classification results have been added in remarks column.
  13. International Chemical Safety Cards (ICSC)
      2 substances have been added.
  14. US Agency for Toxic Substances and Disease Registry (ATSDR): Toxicological Profiles
      3 substances have been added and 1 substance has been revised based on the list of 2017/9/27 updated.
  15. JSOH: Occupational Exposure Limits
      3 substances have been added and 7 substances have been revised based on the list of FY2017 publication.
  16. JSOH: Occupational Carcinogens
      5 substances have been added and 17 substances have been revised based on the list of FY2017 publication.
  17. JSOH: Occupational Sensitizers
      3 substances have been added and 3 substances have been revised based on the list of FY2017 publication.
  18. JSOH: Reproductive Toxicants
      2 substances have been added and 1 substance has been revised based on the list of FY2017 publication.
  19. Japan METI: Biodegradation and Bioconcentration Results
      The judgement results of Newly Announced Chemical Substances (given public notice on 2017/7/31): 237 substances have been added.
  20. General Information: Chemical Substance Name
      257 substance names have been updated.
  21. General Information: Structure and Data for structure search
      Structures for 218 substances have been updated.
      205 Data for structure search have been updated.
  22. Molecular weight and formula
      224 molecular formula data have been updated.
Regarding Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 30 KB].

 October 3, 2017

Following data have been updated.
  1. CSCL: Existing Chemical Substances
      Confirmed links of CAS Registry Number : 1 link has been added.
  2. ISHA: Existing Chemical Substances
      English names (serial number 2001-4000) have been added.
      1 ISHA number has been revised.
  3. ISHA: Newly Announced Chemical Substances
      245 substances have been added as Newly Announced Chemical Substances. (Public Notice 2017/6/27).
  4. ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc.
      1 substance has been added and 1 substance has been deleted based on the enforcement of 2017/8/3.
      The information on the addition of 9 substances and the modification of 1 Cabinet Order Name and 1 Cabinet Order Number that will be enforced on 2018/7/1 has been added.
      For related items, the term of "To be enforced from July 1, 2018" is written in the column of "Cabinet Order Number".
  5. Water Pollution Control Law
      16 exemplified substances have been added and 1 exemplified substance has been deleted by reviewing the data.
  6. Rotterdam Convention on the Prior Informed Consent Procedure for Certain Hazardous Chemicals and Pesticides in International Trade (PIC)
      2 substances have been added to the Pesticide and the Industrial respectively (Effective 2017/09/15).
      1 exemplified substance has been added and 1 exemplified substance has been deleted by reviewing the data.
  7. The ASEAN-Japan Chemical Safety Database (AJCSD): Laws and Regulations
      10 substances have been deleted because of update of AJCSD.
  8. Korea: Act on the Registration and Evaluation, etc. of Chemical Substances (ARECs) / Chemicals Control Act (CCA)
      41 substances of Toxic Substance(s) have been added based on the notification of 2017/7/7 and 9/1.
  9. IARC: Carcinogenicity Assessment
      4 substances have been added, 4 substances have been changed in the group based on the list updated on 2017/06/28.
  10. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
      1 draft has been revised to full report based on the list of September 1, 2017 updated.
  11. General Information: Chemical Substance Name
      1293 substance names have been updated.
  12. General Information: Structure and Data for structure search
      Structures for 726 substances have been updated.
      709 Data for structure search have been updated.
  13. Molecular weight and formula
      849 molecular formula data have been updated.
Regarding Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 30 KB].

 July 31, 2017

Following information has been added newly.
    CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
Following data have been updated.
  1. CSCL: Priority Assessment Chemical Substances
      Confirmed links of CAS Registry Number : 13 links have been added.
  2. CSCL: Newly Announced Chemical Substances (notified on and after April 1, 2011)
      237 substances have been added based on the notification of 2017/7/31.
      1 substance (The designation as a priority assessment chemical substance was cancelled on 2017/3/30) has been added.
  3. CSCL: Newly Announced Chemical Substances (notified by March 31, 2011)
      Confirmed links of CAS Registry Number : 3 links have been added.
      1 substance (The designation as a priority assessment chemical substance was cancelled on 2017/3/30) has been deleted.
  4. CSCL: Existing Chemical Substances
      Confirmed links of CAS Registry Number : 24 links have been added and 29 links have been deleted.
  5. CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed links of CAS Registry Number : 10 links have been added.
  6. CSCL: Type III Monitoring Chemical Substances (before amendment)
      Confirmed links of CAS Registry Number : 20 links have been added.
  7. CSCL: Chemical Substances not regarded as a New Chemical Substances
      18 substances have been added.
  8. ISHA: Existing Chemical Substances
      Confirmed links of CAS Registry Number : 2 links have been added.
      English names (serial number 1-2000) have been added.
  9. ISHA: Newly Announced Chemical Substances
      Confirmed links of CAS Registry Number : 9 links have been added and 2 links have been changed.
      Confirmed links of MITI number : 2 links have been added.
  10. Poisonous and Deleterious Substances Control Act
      2 substances have been added and 5 Cabinet Order Names have been modified based on the notification of 2017/6/14.
  11. Air Pollution Control Law
      1 substance has been added by reviewing the data.
  12. Water Pollution Control Law
      5 substances have been added by reviewing the data.
  13. REACH: Substances of Very High Concern for Authorization (SVHC)
      12 substances have been added to Authorisation List. (2017/6/14)
      1 substance has been added to Candidate List. (2017/7/7)
  14. TSCA Inventory
      28 substances have been added, 13 names have been changed and "ACTIVE" information has been added to 9,868 substances based on the list of 2017/6/27 updated.
  15. Korea: Act on the Registration and Evaluation, etc. of Chemical Substances (ARECs) / Chemicals Control Act (CCA)
      28 substances of Accident Precaution Chemical have been added based on the notification of 2017/6/2.
  16. GHS Classification Results by the Japanese Government
      179 classification results in 2016FY have been added.
  17. AJCSD: GHS Classification Results / Sample SDS
      31 substances have been added because GHS Classification Results by the Myanmar Government have been added to AJCSD.
  18. IARC: Carcinogenicity Assessment
      Data of 8 agents have been changed based on the list updated on 2017/5/19.
  19. Japan METI: Biodegradation and Bioconcentration Results
      5 results of Bioaccumulation test or Partition coefficient test have been added and 1 result has been changed.
      Confirmed links of CAS Registry Number : 4 links have been added.
  20. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
      3 drafts have been added based on the list of May 2017 updated.
  21. General Information: Chemical Substance Name
      86 substance names have been maintained.
  22. General Information: Structure and Data for structure search
      Structures for 72 substances have been maintained.
      71 Data for structure search have been maintained.
  23. Molecular weight and formula
      73 molecular formula data have been maintained.
      1 molecular weight datum has been revised.
Following links to source of information, etc. at search results page have been added newly.
  1. CSCL
    Class I Specified Chemical Substances, Class II Specified Chemical Substances, Monitoring Chemical Substances, Priority Assessment Chemical Substances, Newly Announced Chemical Substances (notified on and after April 1, 2011), Newly Announced Chemical Substances (notified by March 31, 2011), Existing Chemical Substances, Type II Monitoring Chemical Substances (before amendment), Type III Monitoring Chemical Substances (before amendment), Chemical Substances not regarded as a New Chemical Substances
  2. ISHA
    Existing Chemical Substances, Newly Announced Chemical Substances, Chemical Substances requiring Labeling and Deliver of Documents, etc., Specified Chemical Substances, Lead, etc. / Tetraalkyl lead, etc, Organic Solvents, Administrative Control Levels of Working Environment Evaluation Standards, Strong Mutagenic Chemical Substances
  3. Poisonous and Deleterious Substances Control Act
  4. Act on the Prohibition of Chemical Weapons and the Control, etc. of Specific Chemicals (Chemical Weapons Prohibition Law)
  5. Act on the Protection of the Ozone Layer through the Control of Specified Substances and Other Measures
  6. Air Pollution Control Law
  7. Water Pollution Control Law
  8. Soil Contamination Countermeasures Act
  9. Law for the Control of Household Products Containing Harmful Substances
Regarding Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 33 KB].

 June 6, 2017

Following data have been updated.
  1. CSCL: Newly Announced Chemical Substances
      Confirmed links of CAS Registry Number : 3 links have been added.
  2. CSCL: Existing Chemical Substances
      Confirmed links of CAS Registry Number : 9 links have been added and 1 link has been changed.
  3. CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed links of CAS Registry Number : 4 links have been added.
  4. CSCL: Type III Monitoring Chemical Substances (before amendment)
      Confirmed links of CAS Registry Number : 2 links have been added.
  5. CSCL: Chemical Substances not regarded as a New Chemical Substances
      2 substances have been added and 3 substances have been changed.
  6. ISHA: Newly Announced Chemical Substances
      215 substances have been added as Newly Announced Chemical Substances. (Public Notice 2017/3/27)
      Confirmed links of CAS Registry Number : 2 links have been added.
      English names (serial number 21001-24781) have been added.
  7. ISHA: Specified Chemical Substances
      1 substance has been added based on the notification of 2017/4/27.
  8. ISHA: Administrative Control Levels of Working Environment Evaluation Standards
      1 substance has been added based on the notification of 2017/4/27.
  9. EC Inventory
      EC Name and Description in Search Results screen have been changed.
  10. Korea: Act on the Registration and Evaluation, etc. of Chemical Substances (ARECs) / Chemicals Control Act (CCA)
      771 substances of Toxic Substance(s) have been added.
      8 exemplified substances of Restricted Substance(s) have been added.
      Range of application has been added and KE number and substances not listed in Official Gazette have been deleted.
  11. IARC: Carcinogenicity Assessment
      2 substances have been added, 1 agent has been changed in the group and data of 2 agents have been changed based on the list updated on 2017/4/13.
  12. EU: Carcinogenicity Assessment
      9 substances have been added to Category 1B and 7 substances have been added to Category 2 based on the list of 2017/5/5 published.
  13. Japan METI: Biodegradation and Bioconcentration Results
      The judgement result of the bioconcentration of degradation products of new chemical substances and the test result for the evaluation (Published 2017/4/4) : 30 substances have been added.
  14. General Information: Chemical Substance Name
      918 substance names have been maintained.
  15. General Information: Structure and Data for structure search
      Structures for 857 substances have been added.
      854 Data for structure search have been added.
  16. Molecular weight and formula
      907 molecular formula data have been maintained.
Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 41 KB].

 May 8, 2017

In the April 18, 2017 update, chloroethylene (CAS Registry Number: 75-01-4) was incorrectly listed as "Class 3" for Soil Contamination Countermeasures Act. In this update, it is reclassified as "Class 1".

 April 18, 2017

Following data have been updated.
  1. CSCL: Priority Assessment Chemical Substances
      16 substances have been added based on the notification of 2017/4/3.
      11 substances have been deleted based on the notification of 2017/3/30 and 4/3.
  2. CSCL: Newly Announced Chemical Substances
      4 substance names have been changed based on the notification of 2017/3/31.
      1 chemical substance (The designation as a priority assessment chemical substance was cancelled on 2017/3/30) has been added.
  3. CSCL: Existing Chemical Substances
      Confirmed links of CAS Registry Number : 6 links have been deleted.
  4. CSCL: Type II Monitoring Chemical Substances (before amendment)
      1 substance name has been changed based on the notification of 2017/3/31.
  5. CSCL: Chemical Substances exempted from notification of manufacturing/import amount
      123 substances have been added based on the notification of 2017/3/27.
  6. CSCL: Chemical Substances not regarded as a New Chemical Substances
      4 substances have been added and 1 substance has been deleted as Substances not regarded as a New Chemical Substances.
  7. Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
      12 exemplified substances have been added.
  8. Soil Contamination Countermeasures Act
      1 substance has been added based on the notification of 2016/3/29.
  9. Law for the Control of Household Products Containing Harmful Substances
      2 Data Descriptions have been changed.
  10. UN Number and UN Hazard Class
      UN Number for 1 substance has been changed by reviewing the data.
  11. The ASEAN-Japan Chemical Safety Database (AJCSD): Laws and Regulations
      19864 substances have been added because Philippines PICCS lists have been added to AJCSD.
      1 substance has been changed by reviewing the data.
  12. EC Inventory
      Detail of EC name at Description in Search Results screen has been displayed.
  13. TSCA Inventory
      81 substances have been added, 9 substance names have been changed and 9 substances have been deleted based on the list of 2017/2/27 publication.
  14. China: Catalog of Hazardous Chemicals 2015
      Confirmed links of CAS Registry Number : 1 link has been changed.
  15. GHS Classification Results by the Japanese Government
      The link to source of information, etc. at search results screen has been added.
  16. IARC: Carcinogenicity Assessment
      50 Additional information has been changed.
  17. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed links of CAS Registry Number : 1 link has been deleted.
  18. Japan MHLW: Toxicity Test Results
      18 substances have been changed based on the list updated on March 2017.
  19. General Information: Chemical Substance Name
      26 substance names have been maintained.
Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 26 KB].

 March 21, 2017

Following data have been updated.
  1. CSCL: Class I Specified Chemical Substances
      Confirmed links of CAS Registry Number : 1 link has been added.
  2. CSCL: Priority Assessment Chemical Substances
      Confirmed links of CAS Registry Number : 19 links have been added.
  3. CSCL: Newly Announced Chemical Substances
      Confirmed links of CAS Registry Number : 5 links have been added.
  4. CSCL: Existing Chemical Substances
      Confirmed links of CAS Registry Number : 22 links have been added and 35 links have been deleted.
  5. CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed links of CAS Registry Number : 2 links have been added.
  6. CSCL: Type III Monitoring Chemical Substances (before amendment)
      Confirmed links of CAS Registry Number : 1 link has been added.
  7. CSCL: Chemical Substances not regarded as a New Chemical Substances
      The notation method of an official daily gazette public announcement reference number and/or an government ordinance number referred to as grounds has been changed.
      37 substances have been added and 15 substances have been deleted as Substances not regarded as a New Chemical Substances
  8. ISHA: Existing Chemical Substances
      Confirmed links of CAS Registry Number : 1 link has been added and 1 link has been deleted.
  9. ISHA: Newly Announced Chemical Substances
      180 substances have been added as Newly Announced Chemical Substances. (Public Notice 2016/12/27)
      Confirmed links of CAS Registry Number : 4 links have been deleted and 3 links have been added.
      English names (serial number 18001-21000) have been added.
  10. ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc.
      3 exemplified substances have been added. The information before the enforcement on 2017/3/1 has been deleted.
  11. ISHA: Strong Mutagenic Chemical Substances
      35 substances have been added in Existing Chemical Substances and 47 substances have been added in Notified Chemical Substances. (Annouced 2016/12/9)
  12. Poisonous and Deleterious Substances Control Act
      1 exemplified substance has been added.
  13. REACH: Substances of Very High Concern for Authorization (SVHC)
      4 substances have been added for Candidate List. (2017/01/12)
  14. TSCA Inventory
      145 names have been changed based on the list of 2016/7/12 publication.
  15. TSCA: Significant New Use Rule (SNUR)
      32 rules have been added up to 2017/1/19 effectuation.
  16. US Agency for Toxic Substances and Disease Registry (ATSDR): Toxicological Profiles
      1 substance has been changed based on the list updated on 2016/9/15.
  17. US EPA: Integrated Risk Information System (IRIS)
      1 substance has been added based on the list updated on 2016/12/16.
  18. JSOH: Occupational Exposure Limits
      Information on skin absorbtion has been added. 1 CAS number has been added.
  19. US EPA: Carcinogenicity Assessment
      1 substance has been added based on the list updated on 2016/12/16.
  20. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed links of CAS Registry Number : 3 links have been added and 3 links have been deleted.
  21. General Information: Chemical Substance Name
      646 data have been added and 2612 data have been changed.
      268 substance names have been maintained.
  22. General Information: Structure and Data for structure search
      Structures for 236 substances have been added and 1 substance has been changed.
      208 Data for structure search have been added.
  23. Molecular weight and formula
      255 molecular formula data have been maintained.
Following links to source of information, etc. at search results page have been added newly.
  1. Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
  2. Chemical Substances Hazard Assessment Report / Initial Risk Assessment Report
  3. IARC: Carcinogenicity Assessment
  4. US EPA: Carcinogenicity Assessment
  5. US NTP: Carcinogenicity Assessment
  6. EU: Carcinogenicity Assessment
Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 28 KB].

 January 24, 2017

Following information has been added newly.
    ICCA Safety Summary of Japan (JCIA BIGDr)
Following data have been updated.
  1. CSCL: Priority Assessment Chemical Substances
      Confirmed links of CAS Registry Number : 9 links have been added, 2 links have been changed and 6 links have been deleted.
  2. CSCL: Newly Announced Chemical Substances
      Confirmed links of CAS Registry Number : 4 links have been added and 7 links have been deleted.
  3. CSCL: Existing Chemical Substances
      Confirmed links of CAS Registry Number : 27 links have been added.
  4. CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed links of CAS Registry Number : 29 links have been deleted.
  5. CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed links of CAS Registry Number : 1 link has been added and 1 link has been deleted.
  6. CSCL: Chemical Substances not regarded as a New Chemical Substances
      13 substances have been added and 13 substances have been deleted as Substances not regarded as a New Chemical Substances
  7. ISHA: Newly Announced Chemical Substances
      228 substances have been added as Newly Announced Chemical Substances. (Public Notice 2016/9/27)
      Confirmed links of CAS Registry Number : 2 links have been changed.
      English names (serial number 15001-18000) have been added.
  8. ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc.
      Range of Application for Label (weight%) of 32 exemplified substances of chromium and its compounds has been changed.
  9. ISHA: Specified Chemical Substances
      1 substance has been added based on the notification of 2016/11/30.
      33 exemplified substances of chromic acid and its salts have been deleted by reviewing the data.
  10. ISHA: Administrative Control Levels of Working Environment Evaluation Standards
      1 substance has been added and 1 Registration Number has been changed based on the notification of 2016/11/30.
      33 exemplified substances of chromic acid and its salts have been deleted by reviewing the data.
  11. Stockholm Convention on Persistent Organic Pollutants (POPs)
      3 substances have been added in the Classification of A and 1 substance has been added in the Classification of C. (Effective 2016/12/06)
  12. JSOH: Occupational Sensitizers
      Category has been set on "List Stage One (Decree number etc based)" page.
  13. IARC: Carcinogenicity Assessment
      3 substances have been added, 1 substance has been deleted and 1 substance has been changed in the carcinogenicity classifications based on the list updated on 2016/10/24.
      1 substance has been deleted by reviewing the data.
  14. US NTP: Carcinogenicity Assessment
      Based on the 14th Report on Carcinogens of 2016/11/3 publication, 6 substances have been added, 2 substances have been deleted and 1 substance has been changed.
  15. Japan METI: Biodegradation and Bioconcentration Results
      112 results of Bioaccumulation test or Partition coefficient test have been described.
  16. US National Toxicology Program (NTP): Long-Term Study Reports & Abstracts
      1 draft has been revised to full report based on the list of November 2016 annouced.
  17. General Information: Chemical Substance Name
      541 substance names have been maintained.
      29 data have been added and 25 data have been changed.
  18. General Information: Structure and Data for structure search
      Structures for 493 substances have been added and 1 substance has been changed.
      451 Data for structure search have been added.
  19. Molecular weight and formula
      516 molecular formula data have been maintained.
Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 26 KB].

 November 29, 2016

Following information has been added newly.
    Water Pollution Control Law : Designated substances
Following data have been updated.
  1. ISHA: Newly Announced Chemical Substances
      222 substances have been added as Newly Announced Chemical Substances. (Public Notice 2016/6/27)
      Confirmed links of CAS Registry Number : 1 link has been added.
      The ISHA number of serial number 6546 has been changed.
      English names (serial number 12001-15000) have been added.
  2. ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc.
      The information for the enforcement on 2017/3/1 and 27 substances have been added.
      For related items, the term of "To be enforced from March 1, 2017" is written in the column of "Cabinet Order Number".
  3. ISHA: Specified Chemical Substances
      1 exemplified substance has been deleted.
  4. Poisonous and Deleterious Substances Control Act
      1 exemplified substance has been added.
  5. US EPA: Integrated Risk Information System (IRIS)
      3 substances have been added based on the list updated on 2016/9/9.
      1 substance has been added and 1 substance has been deleted by reviewing the data.
  6. EU: Risk Assessment Reports (RAR)
      The EC number has been displayed on the screen of List Stage One(Decree number etc based) and Search Results.
  7. JSOH: Occupational Exposure Limits
      2 substances have been added and 9 substances have been changed based on the list of FY2016 publication.
  8. JSOH: Occupational Carcinogens
      5 substances have been added and 20 substances have been changed based on the list of FY2016 publication.
  9. JSOH: Occupational Sensitizers
      2 substances have been added and 1 substance has been changed based on the list of FY2016 publication.
  10. JSOH: Reproductive Toxicants
      1 substance has been added and 3 substances have been changed based on the list of FY2016 publication.
  11. IARC: Carcinogenicity Assessment
      9 substances have been added and 2 substances have been deleted based on the list updated on 2016/9/16.
  12. US EPA: Carcinogenicity Assessment
      3 substances have been added and 8 substances have been deleted based on the list updated on 2016/9/9.
      1 substance's CAS Registry number has been deleted by reviewing the data.
  13. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed link of CAS Registry Number : 1 link has been added and 1 link has been deleted.
      52 links to J-CHECK have been changed.
  14. General Information: Chemical Substance Name
      601 substance names have been maintained.
      4 data have been added and 36 data have been changed.
  15. General Information: Structure and Data for structure search
      Structures for 593 substances have been added and 1 substance has been changed.
      555 Data for structure search have been added.
  16. Molecular weight and formula
      599 molecular formula data have been maintained.
      1 molecular weight data has been changed.
Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 22 KB].

 October 4, 2016

Following data have been updated.
  1. CSCL: Priority Assessment Chemical Substances
      Confirmed link of CAS Registry Number : 1 link has been added.
  2. CSCL: Newly Announced Chemical Substances
      Confirmed links of CAS Registry Number : 13 links have been added.
  3. CSCL: Existing Chemical Substances
      Confirmed links of CAS Registry Number : 2 links have been added.
  4. CSCL: Not Regarded as a New Chemical Substance
      2 substances have been added as not regarded as a new chemical substance.
  5. ISHA: Existing Chemical Substances
      Confirmed links of CAS Registry Number : 2 links have been added.
      Confirmed links of MITI number : 2 links have been added.
  6. ISHA: Newly Announced Chemical Substances
      English names of Newly Announced Chemical Substances (serial number 9001-12000) have been added.
      Confirmed links of MITI number : 23 links have been added.
  7. ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc.
      18 substances have been added.
  8. ISHA: Specified Chemical Substances
      The range of content (% by weight) of regulated substances in preparations, etc. is displayed.
  9. ISHA: Lead, etc. / Tetraalkyl lead, etc
      1 exemplified substance has been deleted.
  10. ISHA: Administrative Control Levels of Working Environment Evaluation Standards
      2 substances have been added and 1 Cotrol Level and 1 Registration Number have been changed based on the notification of 2015/9/30.
  11. Poisonous and Deleterious Substances Control Act
      A list about the exclusion material of "Organic cyanide compounds and preparations containing it" can be referenced at Data Description.
      1 Cabinet Order Name has been changed.
  12. Rotterdam Convention on the Prior Informed Consent Procedure for Certain Hazardous Chemicals and Pesticides in International Trade (PIC)
      3 substances have been added based on a notification of 2016/3/18 official announcement.
  13. ASEAN-Japan Chemical Safety Database (AJCSD) : Laws and Regulations
      20 substances have been added because Myanmer Restricted and Prohibited Chemicals lists have been added to AJCSD.
  14. TSCA Inventory
      2 names have been changed based on the list of 2016/7/12 publication.
  15. TSCA: Significant New Use Rule (SNUR)
      47 rules have been added up to 2016/7/15 effectuation.
  16. US EPA: Integrated Risk Information System (IRIS)
      51 substances have been deleted and 1 substance has been deleted based on the list updated on July 2016 .
  17. IARC: Carcinogenicity Assessment
      3 exemplified substances have been added.
  18. EU: Carcinogenicity Assessment
      3 substances have been added to Category 1B and 6 substances have been added to Category 2, and 1 substance has been changed in name based on the list of 2016/7/20 published.
  19. Japan METI: Biodegradation and Bioconcentration Results
      Evaluation results (Published 2016/09/07) of 177 substances have been added.
      Confirmed link of CAS Registry Number : 1 link has been deleted by reviewing the data.
  20. General Information: Chemical Substance Name
      510 substances have been maintained.
      469 data have been changed.
  21. General Information: Structure and Data for structure search
      Structures for 498 substances have been added.
      436 Data for structure search have been added.
  22. Molecular weight and formula
      500 molecular formula data have been maintained.
Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 17 KB].

 July 29, 2016

Following information has been added newly.
  1. China: Catalog of Hazardous Chemicals 2015
  2. The ASEAN-Japan Chemical Safety Database (AJCSD): Laws and Regulations
  3. AJCSD: GHS Classification Results
Following data have been updated.
  1. CSCL : Newly Announced Chemical Substances
      177 substances have been added based on the notification of 2016/7/29.
      Confirmed links between MITI number and CAS Registry Number : 19 links have been added.
  2. CSCL : Existing Chemical Substances
      Confirmed links between MITI number and CAS Registry Number : 8 links have been added and 40 links have been deleted.
  3. CSCL: Not Regarded as a New Chemical Substance
      2 substances have been added as not regarded as a new chemical substance
  4. CSCL : Class I and II Specified Chemical Substances
      3 substances regarded as " Class I and II Specified Chemical Substances " have been added.
  5. Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
      Links for Releases Map and Atmospheric concentration Map have been updated to PRTR Map. (Public Notice 2016/3/31)
  6. ISHA: Newly Announced Chemical Substances
      224 substances have been added as Newly Announced Chemical Substances. (Public Notice 2016/3/25)
      English names (serial number 6001-9000) have been added.
      Confirmed links of CAS Registry Number : 130 links have been added and 1 link has been deleted.
  7. ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc.
      1 substance has been added and 1 Cabinet Order English Name has been changed by reviewing the data.
  8. Poisonous and Deleterious Substances Control Act
      9 substances have been added and 3 Cabinet Order Names have been changed based on the notification of 2016/7/1.
  9. UN Number and UN Hazard Class
      2 substances have been deleted by reviewing the data.
  10. REACH: Substances of Very High Concern for Authorization (SVHC)
      1 substance has been added for Candidate List. (2016/6/20)
  11. TSCA Inventory
      106 substances have been added based on the list of 2016/5/31 publication.
  12. TSCA: Significant New Use Rule (SNUR)
      1 rule has been added and 1 substance has been added based on the list of 2016/6/7 effectuation.
  13. GHS Classification Results by the Japanese Government
      405 Data have been added. (Classified in FY2014 and FY2015)
  14. International Chemical Safety Cards (ICSC)
      1 CAS Registry Number has been changed by reviewing the data.
  15. JSOH: Occupational Exposure Limits
      1 substance has been changed and 10 exemplified substances have been added by reviewing the data.
      3 substances have been added as Reference values corresponding to an individual excess lifetime risk of cancer (Table III-2).
  16. IARC: Carcinogenicity Assessment
      1 substance has been added and 1 substance has been changed in the carcinogenicity classifications based on the list of 2016/6/15 publication.
  17. Japan METI: Biodegradation and Bioconcentration Results
      Confirmed links between MITI number and CAS Registry Number : 2 links have been added.
  18. General Information: Chemical Substance Name
      1217 substances have been added and 955 substances about Chemical Substance Names (Japanese and English) have been changed.
  19. General Information: Structure and Data for structure search
      Structures for 932 substances have been added and 3 substances have been changed.
      888 Data for structure search have been added.
  20. Information of Japan Chemical Substance Dictionary (Nikkaji)
      The link has been changed from Nikkaji web site to J-GLOBAL.
      45 substances have been added and 4 substances have been deleted
Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 30 KB].

 May 31, 2016

Following data have been updated.
  1. CSCL: Priority Assessment Chemical Substances
      203 substances regarded as "priority assessment chemical substances" have been added.
  2. ISHA: Newly Announced Chemical Substances
      English names (serial number 3001-6000) have been added.
  3. ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc.
      “ISHA: Chemical Substances requiring Labeling, etc.” and “ISHA : Chemical Substances requiring Deliver of Documents, etc.” have been deleted and unified into “ISHA : Chemical Substances requiring Labeling and Deliver of Documents, etc.”.(Enforced from 2016/6/1)
  4. TSCA: Significant New Use Rule (SNUR)
      3 rules have been added up to 2016/4/12 effectuation.
  5. International Chemical Safety Cards (ICSC)
      3 substances have been added and the link from detail information has been changed from IPCS site to ILO site.
  6. US Agency for Toxic Substances and Disease Registry (ATSDR): Toxicological Profiles
      Two substances have been added and two substances have been changed based on the list of 2016/3/2 updated.
  7. Japan MOE: Results of Eco-toxicity tests of chemicals
      1 substance has been added based on the data of 2016/3 publication.
  8. NITE: Toxicity and Eco-toxicity Test Results
      The link from test results has been changed to J-CHECK.

Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 16 KB].

 April 25, 2016

Following data have been updated.
  1. CSCL: Class I Specified Chemical Substances
      1 substance (Pentachlorophenol, its salts or esters) has been added and 1 substance “Polychlorinated naphthalenes (only those containing 3 or more chlorine atoms in the molecule)” has been changed to “Polychlorinated naphthalenes (only those containing 2 or more chlorine atoms in the molecule” based on the notification of 2016/3/2.
  2. CSCL: Priority Assessment Chemical Substances
      21 substances have been added based on the notification of 2016/4/1.
  3. CSCL: Newly Announced Chemical Substances
      Confirmed links between MITI number and CAS Registry Number : 3 links have been added.
  4. CSCL: Existing Chemical Substances
      Confirmed links between MITI number and CAS Registry Number : 23 links have been added and 5 links have been deleted.
  5. CSCL: Type II Monitoring Chemical Substances (before amendment)
      Confirmed links between MITI number and CAS Registry Number : 3 links have been added.
  6. CSCL: Chemical Substances exempt from notification of manufacturing/import amount
      Public notice 2016/3/24 has been reflected.
  7. CSCL: Not Regarded as a New Chemical Substance
      22 substances have been added as not regarded as a new chemical substance.
  8. ISHA: Newly Announced Chemical Substances
      English names (serial number 1-3000) have been added.
  9. ISHA: Chemical Substances requiring Deliver of Documents, etc.
      10 exemplified substances have been added.
  10. ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc.: To be enforced from June 1, 2016
      10 exemplified substances have been added.
  11. IARC: Carcinogenicity Assessment
      4 substances have been added and 3 substances have been changed in the carcinogenicity classifications based on the list of 2016/2/22 publication.
  12. Japan MHLW: Toxicity Test Results
      4 substances have been added and 2 substances have been deleted in the carcinogenicity classifications based on the list of 2016/3 publication.
  13. US National Toxicology Program (NTP): Long-Term Study Reports & Abstracts
      2 abstracts have been revised to full reports respectively based on the list of 2016/2/1 published.

Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 15 KB].

 April 7, 2016

NITE-CHRIP has been renewed. The main changes are as follows.
  1. Search by CHRIP_ID and the UN number became possible.
  2. Search results can be filtered by all of information and categories.
  3. Search with more specific conditions using wild cards (*, ?) is available. (Search Options)
  4. All search results became downloadable.
  5. Search results can be linked directly by using CHRIP_ID.

Following information has been added newly.
  1. ISHA: Announced Chemical Substances (Existing / Newly)
      The English chemical substance names are in preparation. NITE will translate them in order of precedence.
  2. ISHA: Strong Mutagenic Chemical Substances (Notified Chemical Substances)
  3. ISHA: Chemical Substances requiring Labeling and Deliver of Documents, etc.: To be enforced from June 1, 2016
  4. Japan Society for Occupational Health (JSOH) Recommendation of Occupational Exposure Limits

Following data have been updated.
  1. CSCL: Priority Assessment Chemical Substances
       Two substances have been deleted (Public Notice 2016/3/28)
  2. OECD: High Production Volume (HPV) Chemicals
       Because the links to "SIAP" (UNEP site) no longer work, they have been changed to the web site of OECD Existing Chemicals Database.

Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment [PDF markPDF 9 KB].

 February 9, 2016

Following data have been updated.
  1. Chemical Substances Control Law : Existing Chemical Substances
       Confirmed links between MITI number and CAS Registry Number : 1 link has been deleted.
  2. Chemical Substances Control Law : Newly Announced Chemical Substances prescribed in Paragraph (4) of Article 4 of the Former Act
       Confirmed links between MITI number and CAS Registry Number: 1 link has been added.
  3. Chemical Substances Control Law :.Biodegradation and Bioconcentration Results
       1 Evaluation result of Newly Announced Chemical Substance (MTI 2-4151) has been changed. (Amendment 2016/1/5)
       Confirmed links between published evaluation results and CAS Registry Number : 1 link has been added and 1 link has been deleted.
  4. Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof : Class I Designated Chemical Substances
       1 exemplified substance has been deleted.
  5. Poisonous and Deleterious Substances Control Act
       11 exemplified substances have been added.
  6. Industrial Safety and Health Act : Labeling, etc.
       403 exemplified substances have been added, to be consistent with Specified Chemical Substances of the Industrial Safety and Health Act.
  7. Industrial Safety and Health Act : Deliver of Documents, etc.
       511 exemplified substances have been added, to be consistent with Specified Chemical Substances of the Industrial Safety and Health Act.
  8. Industrial Safety and Health Act : Mutagenicity Test Results for Existing Chemical Substances
       25 substances have been added. ( 2015/12/7)
  9. Act on the Protection of the Ozone Layer through the Control of Specified Substances and Other Measures
       The Cabinet Order No. of 1 exemplified substance has been corrected.
  10. REACH : Substances of Very High Concern for Authorisation
       5 substances (7 CAS Registry Numbers) have been added for Candidate List. ( 2015/12/17)
  11. Toxic Substances Control Act (TSCA) : Significant New Use Rules (SNUR)
       4 rules have been added. (2016/2/2)
  12. Rotterdam Convention on the Prior Informed Consent (PIC) procedure for certain hazardous chemicals and pesticides in international trade
       1 substance has been changed in the name and category.
  13. US Agency for Toxic Substances and Disease Registry (ATSDR) : Toxicological Profiles
       3 profiles (7 substances) and one exemplified substance have been added by the review of the list and report.
  14. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
       2 reports have been added. ( 2015/12/21)
  15. Physical and Chemical Properties
       Properties of 2 substances have been changed.
  16. General Information: Chemical Substance Name
       812 substances have been added and 1,196 substances have been changed.
  17. General Information: Structure and Data for structure search
       Structures for 1,756 substances have been added and 8 substances have been changed.
      1,191 Data for structure search have been added.

Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 29 KB].

 December 17, 2015

Following data have been updated.
  1. Chemical Substances Control Law : Existing Chemical Substances
      Confirmed links between MITI number and CAS Registry Number: 68 links have been added and 59 links have been deleted.
      1 substance (3-193) has been deleted.
  2. Chemical Substances Control Law : Type II Monitoring Chemical Substances (before amendment) , Type III Monitoring Chemical Substances (before amendment)
      Confirmed links between MITI number and CAS Registry Number: 2 links have been added, and 1 link has been deleted.
  3. Chemical Substances Control Law : Priority Assessment Chemical Substances
      Confirmed links between MITI number and CAS Registry Number: 1 link has been deleted.
  4. Chemical Substances Control Law : Newly Announced Chemical Substances prescribed in Paragraph (4) of Article 4 of the Former Act
      Confirmed links between MITI number and CAS Registry Number: 68 links have been added.
  5. Chemical Substances Control Law : Not Regarded as a New Chemical Substance
      Confirmed links between the substances (Not Regarded as a New Chemical Substance) and CAS Registry Number: 55 links have been added.
  6. Chemical Substances Control Law :.Biodegradation and Bioconcentration Results
      185 Evaluation results (Published 2015/10/14) of Newly Announced Chemical Substances have been added.
      Confirmed links between published evaluation results and CAS Registry Number: 258 links have been added.
      Information of 15 substances have been updated.
  7. Industrial Safety and Health Act : Relevant Ordinances
      2 substances have been added as Specified Chemical Substances, and the Cabinet Order No. of 1 substance has been changed. Administrative control level of one Specified Chemical Substance has been updated. (Public Notice 2015/8/12 and 2015/9/30)
  8. Industrial Safety and Health Act : Labeling, etc.
      2 substances have been added (Public Notice 2015/8/12 and 2015/9/17) and the Cabinet Order Name of 1 substance has been replaced by reviewing the data.
  9. Industrial Safety and Health Act : Deliver of Documents, etc.
      1 substance has been added (Public Notice 2015/9/17) and the Cabinet Order Name of 1 substance has been replaced by reviewing the data.
  10. Water Pollution Control Law and Soil Contamination Countermeasures Act
      The Effluent Standard of trichloroethylene has been changed. (Public Notice 2015/9/18)
  11. UN Number and UN Hazard Class
      Based on the Dangerous Goods List of Rev.19 (2015), 9 UN Numbers (510 and 3527-3534) have been added. 1 UN Number(3507) has been changed in Class and division and 5 UN Numbers (3151, 3152, 3166, 3269 and 3509) have been changed in Name and description.
  12. European Inventory of Existing Commercial Chemical Substances (EINECS)
      1 CAS Registry Number linked to EC Number 310-127-6 has been deleted by reviewing the data.
  13. Toxic Substances Control Act (TSCA) : List of Existing Chemicals & Significant New Use Rules (SNUR)
       List --- 118 substances have been added based on the list of 2015/8/4 publication.
       SNUR --- 21 rules have been added up to 2015/12/1 effectuation.
  14. OECD : HPV Chemicals
      1 CAS Registry Number has been deleted by reviewing the data.
  15. US Environmental Protection Agency (EPA) : Integrated Risk Information System (IRIS)
      All URL To EPA site have been changed to new URL.
  16. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
      1 report has been added and 2 abstracts have been revised to full reports respectively based on the list of 2015/6/17 published.
  17. International Agency for Research on Cancer (IARC) : Carcinogen Risk Assessment
      2 agents have been added in the carcinogenicity classifications based on the list of 2015/10/26 updated and 1 CAS Registry Number has been changed by reviewing the data.
  18. Ministry of Economy, Trade and Industry (METI) Safety Test Results
      The link from "Detail" has been changed to J-CHECK.
  19. General Information: Chemical Substance Name
      1511 substances have been added and 539 substances have been changed.
  20. General Information: Structure and Data for structure search
      Structures for 1905 substances have been added and 18 substances have been changed.
      1227 Data for structure search have been added.

Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 25 KB].

 October 13, 2015

Following data have been updated.
  1. Chemical Substances Control Law :.Biodegradation and Bioconcentration Results
       Information has been added to 52 CAS numbers and 5 CAS numbers have been deleted.
  2. Industrial Safety and Health Act concerning Labeling, etc. and Deliver of Documents, etc.
       The information for the enforcement on 2016/6/1 has been added. (Refer to the lower Note.)
  3. Industrial Safety and Health Act : Mutagenicity Test Results for Existing Chemical Substances
       2 CAS numbers have been added.
  4. Toxic Substances Control Act (TSCA) : Significant New Use Rules (SNUR)
       20 rules have been added and 3 rules have been changed up to 2015/9/2 effectuation.
  5. Korea : Act on the Registration and Evaluation, etc. of Chemical Substances / Chemicals Control Act
       510 Phase-in substance(s) subject to registration (518 CAS numbers) have been added.
  6. International Chemical Safety Cards (ICSC)
       3 Substance has been added.
  7. Australia : Priority Existing Chemicals (PEC) Assessment Reports by the National Industrial Chemicals Notification and Assessment Scheme (NICNAS)
       1 report has been added based on the data of 2015/7 publication.
  8. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
       1 abstract was revised to a full report respectively based on the list of 2015/6/17 updated.
  9. International Agency for Research on Cancer (IARC) : Carcinogen Risk Assessment
       2 substances have been added and 1 substance has been changed in the carcinogenicity classifications based on the list of 2015/8/24 publication.
  10. European Union (EU) : Carcinogen Risk Assessment
       4 substances have been added to Category 2 based on the list of 2015/7/25 published.
  11. NITE Toxicity and Eco-toxicity Test Results
       Contents of the data sheet of 1 substance have been revised.
  12. General Information: Chemical Substance Name
       887 substances have been added and 127 substances have been changed
  13. General Information: Structure and Data for structure search
       Structures for 975 substances have been added and 1 substance has been changed.
       895 Data for structure search have been added.

Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 21 KB].

Note : By the revisions of the Cabinet Order (*1) and the Ministerial Ordinance (*2) of Industrial Safety and Health Act concerning Labeling, etc. and Deliver of Documents, etc., the substances and the cut-off values have been revised and labeling obligation for solid-form substances has been excluded. These will be enforced from June 1, 2016. The substances for Labeling, etc. will be the same as those for Deliver of Documents, etc.
We have added the revised information. For related items, the term of "To be enforced from June 1, 2016" is written in the column of "Law, Cabinet Order or Ministerial Ordinance Number".
(*1) Cabinet Order No. 250 of June 10, 2015
(*2) Ministerial Ordinance No. 115 of June 23, 2015

 July 31, 2015

Following data have been updated.
  1. Chemical Substances Control Law : Newly Announced Chemical Substances prescribed in Paragraph (4) of Article 4 of the Former Act
       185 substances have been added based on the notification of 2015/7/30.
  2. Poisonous and Deleterious Substances Control Act
       3 substances have been added and 3 Cabinet Order Names have been modified based on the notification of 2015/6/19.
  3. Act on the Control of Household Products Containing Harmful Substances
       Applicable Household Goods of the Cabinet Order Name "Azo compounds" have been changed based on the notification of 2015/7/9.
  4. REACH : Substances of Very High Concern for Authorisation
       2 substances (15 items) have been added for Candidate List based on the list of 2015/6/15 updated.
  5. Toxic Substances Control Act (TSCA) : List of Existing Chemicals & Significant New Use Rules (SNUR)
       List --- 67 substances have been added based on the list of 2015/4/13 publication.
    SNUR --- 18 rules have been added up to 2015/7/7 effectuation.
  6. Results from MOE Report on Environmental Survey and Wildlife Monitoring of Chemicals
       Data of 75 substances have been added based on the table of 2015/3 publication.
  7. Australia : Priority Existing Chemicals (PEC) Assessment Reports by the National Industrial Chemicals Notification and Assessment Scheme (NICNAS)
       One report (3 items) has been added based on the data of 2015/5 publication.
  8. Results of Eco-toxicity tests of chemicals conducted by Ministry of the Environment in Japan
       3 substances have been added based on the data of 2015/3 publication.
  9. General Information: Chemical Substance Name
       31 substances have been added and 1 substance has been changed.
  10. General Information: Structure and Data for structure search
       23 substances have been added.

Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 21 KB].

Note : By the revisions of the Cabinet Order (*1) and the Ministerial Ordinance (*2) of Industrial Safety and Health Act concerning Labeling, etc., the substances and the cut-off values have been revised and labeling obligation for solid-form substances has been excluded. These will be enforced from June 1, 2016. The substances for Labeling, etc. will be the same as those for Deliver of Documents, etc. We are currently working on modifying CHRIP to fit the revisions. Thank you for your patience.
(*1) Cabinet Order No. 250 of June 10, 2015
(*2) Ministerial Ordinance No. 115 of June 23, 2015

 June 4, 2015

Following data have been updated.
  1. Chemical Substances Control Law: Toxicity test results
       15 substances have been added based on the data of 2015/3 publication.
  2. Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof : Class I Designated Chemical Substances
       14 exemplified substances have been added.
  3. Poisonous and Deleterious Substances Control Act
       One exemplified substance has been added.
  4. Industrial Safety and Health Act : Labeling, etc.
       13 exemplified substances have been added.
  5. Industrial Safety and Health Act : Deliver of Documents, etc.
       13 exemplified substances have been added.
  6. Industrial Safety and Health Act : Mutagenicity Test Results for Existing Chemical Substances
       The CAS Registry Number has been allocated for one substance.
  7. Act on the Control of Household Products Containing Harmful Substances
       One Cabinet Order Name has been added based on the notification of 2015/4/8.
  8. TSCA : Significant New Use Rules (SNUR)
       19 rules have been added and one rule has been deleted up to 2015/5/26 effectuation.
  9. Korea : Act on Registration, Evaluation, etc. of Chemicals / Chemicals Control Act
       This "Act on Registration, Evaluation, etc. of Chemicals / Chemicals Control Act" replaced the former "Toxic Chemicals Control Act" in January, 2015. Category names of the old act have been changed and the category "Observational Chemicals" has been deleted.
  10. Chemical Substances Control Law: Annual amounts of manufacture and import
       FY2013 Data have been added.
  11. PRTR Data
       PRTR amounts of releases & transfers of up to 2013 have been updated based on the data of 2015/3/6 publication.
  12. International Agency for Research on Cancer (IARC) : Carcinogen Risk Assessment
       2 substances have been added and 3 substances have been changed in the carcinogenicity classifications based on the list of 2015/4/7 publication.

Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 12 KB].

 April 7, 2015

Following data have been updated.
  1. Chemical Substances Control Law : Priority Assessment Chemical Substances
       One substance has been deleted (Public Notice 2015/3/26) and 14 substances have been added (Public Notice 2015/4/1).
  2. Chemical Substances Control Law : Chemical Substances exempt from notification of manufacturing/import amount
       2,295 substances have been updated based on the public notice March 26, 2015.
  3. Confirmed links between the Reference Number by Category in The Gazette List of Existing Chemical Substances (MITI Number) and CAS Registry Number.
       13 Substances have been added and one substance has been deleted.
  4. Industrial Safety and Health Act : Deliver of Documents, etc.
    • The Range of Application (weight%) for Methyl isobutyl ketone has been changed, based on amendment of Ordinance on Industrial Safety and Health (Public Notice 2014/8/25).
    • CAS Registry Number for Dangerous and Harmful Substances Subject to Notify Their Names, etc.: One substance has been deleted by the review of the data.
  5. TSCA : Significant New Use Rules (SNUR)
       One rule has been added up to 2015/4/6 effectuation.

Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 13 KB].

 March 18, 2015

Following data have been updated.
  1. Chemical Substances Control Law : Specified Chemical Substances
       Confirmed link between Class I Specified Chemical Substances (Cabinet Order No. 28) and MITI Number : 2 Substances have been deleted.
       Confirmed link between ClassII Specified Chemical Substances and CAS Registry Number : 2 Substances have been deleted.
  2. Chemical Substances Control Law : Type II Monitoring Chemical Substances (before amendment) , Type III Monitoring Chemical Substances (before amendment)
       Confirmed link between MITI number and CAS Registry Number: 33 Substances have been added, 3 substances have been changed deleted and one substance has been deleted.
  3. Chemical Substances Control Law : Priority Assessment Chemical Substances
       Confirmed link between MITI number and CAS Registry Number: 7 Substances have been added and one substance has been deleted.
  4. Chemical Substances Control Law : Newly Announced Chemical Substances prescribed in Paragraph (4) of Article 4 of the Former Act
       Confirmed link between MITI number and CAS Registry Number: 7 Substances have been added.
  5. Chemical Substances Control Law : Existing Chemical Substances
       Confirmed link between MITI number and CAS Registry Number: 28 Substances have been added and 20 substances have been deleted.
  6. Chemical Substances Control Law : Biodegradation and Bioconcentration Results
       Bioconcentration test results for using to evaluation of new chemical substance (determined in 2010) and its degradation products (Published 2015/2/12): 9 Substances have been added. Previously-published biodegradation and bioconcentration results: 13 Substances have been added.
  7. Industrial Safety and Health Act : Deliver of Documents, etc.
       CAS Registry Number for Dangerous and Harmful Substances Subject to Notify Their Names, etc.: 2 Substances have been added.
  8. UN Number and UN Hazard Class
       7 Substances have been deleted by the review of the data.
  9. TSCA : Significant New Use Rules (SNUR)
       3 Rules and 18 substances have been added and one rule has been revised up to 2015/2/27 effectuation.
  10. Thailand : Hazardous Substances Act (Jurisdiction of the Ministry of Industry, Department of Industrial Works )
       3 Substances have been added based on the official gazette as the List of Hazardous Substances (Public Notice 2015/2/19).
  11. OECD : HPV Chemicals
       The linked URL of the Risk Assessment Report to ECHA have been changed.
  12. US Agency for Toxic Substances and Disease Registry (ATSDR) : Toxicological Profiles
       345 Exemplified substances of the PCB and etc. have been added and 5 CAS Registry Numbers have been changed by the review of the report.
  13. US Environmental Protection Agency : Integrated Risk Information System (IRIS)
       4 Substances have been added and one CAS Registry Number has been changed by the review of the report.
  14. US Environmental Protection Agency (EPA) : Carcinogen Risk Assessment
       4 Substances have been added and 2 CAS Registry Numbers have been changed by the review of the report.
  15. European Union (EU) : Carcinogen Risk Assessment
       The link to EU has been changed from ESIS to ECHA
  16. General Information: Chemical Substance Name
       302 Substances have been added and 1,198 substances have been changed.
  17. General Information: Structure and Data for structure search
       Structures for 210 substances have been added.
       69 Data for structure search have been added.

Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 21 KB].

 February 9, 2015

Following data have been updated.
  1. Chemical Substances Control Law : Biodegradation and Bioconcentration Results
       Bioconcentration test results for using to evaluation of new chemical substance (determined in 2004 to 2007) and its degradation products have been added.(Published 2014/9/10)
  2. Industrial Safety and Health Act : Tests Results of Mutagenicity of Existing Chemical Substances
       20 Substances have been added and one substance has been deleted.
  3. REACH : Substances of Very High Concern for Authorisation
       6 Substances have been added for Candidate List based on the list of 2014/12/17 updated. And one report was revised.
  4. TSCA : Significant New Use Rules (SNUR)
       18 Rules have been added up to 2014/12/26 effectuation.
  5. Thailand : Hazardous Substances Act (Jurisdiction of the Ministry of Industry, Department of Industrial Works )
       Hazardous Substances have been updated based on the official gazette as the List of Hazardous Substances (Public Notice 2013/9/27)
  6. US Agency for Toxic Substances and Disease Registry (ATSDR): Toxicological Profiles
       One substance has been added based on the list of 2014/12/12 updated.
  7. European Union : Risk Assessment Reports (EU : RAR)
       The linked URL of the Risk Assessment Report to ECHA have been changed and 2 substances were deleted based on the new list of ECHA.
  8. International Chemical Safety Cards (ICSC)
       5 Substance has been added.
  9. US Environmental Protection Agency : Integrated Risk Information System (IRIS)
       One substance has been added based on the list of 2014/12/8 updated.
  10. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
       2 Abstracts were revised to a full report respectively based on the list of 2014/12/11 updated.
  11. US Environmental Protection Agency (EPA) : Carcinogen Risk Assessment
       One substance has been added based on the list of 2014/12/8 updated.
  12. General Information: Chemical Substance Name
       608 Substances have been added and 1,893 substances have been changed.
  13. General Information: Structure and Data for structure search
       Structures for 218 substances have been added.
       104 Data for structure search have been added.

Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 13 KB].

The Toxic Chemicals Control Act in Korea has been divided into the Act on Registration, Evaluation, Etc. of Chemicals and the Chemicals Control Act. These new Acts were enforced on January 1, 2015. Please note that information of Korea on CHRIP is outdated.
We are currently working on modifying CHRIP to fit new Acts. Thank you for your patience.

 December 17, 2014

Following data have been updated.
  1. Chemical Substances Control Law : Priority Assessment Chemical Substances
       "Reason for Inclusion" of 7 substances have been updated based on the judgment of 3 ministries (MHLW, METI and MOE) on 2014/11/28.
  2. Chemical Substances Control Law :Type II Monitoring Chemical Substances (before amendment)
       Confirmed link between Type II Monitoring Chemical Substances (before amendment) and CAS Registry Number : One Substance has been deleted.
  3. Chemical Substances Control Law : Biodegradation and Bioconcentration Results
       Evaluation results of Newly Announced Chemical Substances and degradation products 279 substances have been added. (Published 2014/11/6)
  4. Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
       One substance has been added to "Manganese and its compounds" (government ordinance number 412) as an exemplified substance.
  5. Industrial Safety and Health Act : Labeling, etc.
       One Substance has been added. (Public Notice 2014/8/20)
  6. Industrial Safety and Health Act : Relevant Ordinances
       10 Designated Organic solvents have been deleted and 11 substances have been added as Specified Chemical Substances. Administrative control level of one Specified Chemical Substance has been updated. (Public Notice 2014/8/20 and 2014/9/29)
  7. Water Pollution Control Law and Soil Contamination Countermeasures Act
       The Effluent Standard of Cadmium and its compounds has been changed. (Public Notice 2014/11/4)
  8. GHS Classification Results by Japanese Government
       1,136 Data have been added. (Published 2014/11/6)
  9. Toxic Substances Control Act (TSCA) : List of Existing Chemicals & Significant New Use Rules (SNUR)
       List --- 68 Substances have been added based on the list of 2014/7/14 publication.
    SNUR --- 23 Rules have been added up to 2014/11/3 effectuation.
  10. Korea: Toxic Chemicals Control Act (As of September 2014)
       One Substance of Observational Chemicals has been added.
  11. Stockholm Convention on Persistent Organic Pollutants (POPs)
       One Material (5 Substances) have been added by addition of Hexabromocyclododecane (HBCD) to annex A (Elimination). (Effective 2014/11/26)
  12. Environmental Health Criteria (EHC)
       One Item has been added. (No. 242, 2014)
  13. International Agency for Research on Cancer (IARC) : Carcinogen Risk Assessment
       Based on the list of 2014/10/20 publication, 11 substances have been added.
  14. US National Toxicology Program (NTP) : Carcinogen Risk Assessment
       Based on the 13th Report on Carcinogens of 2014/10/2 publication, 10 substances have been added, one substance has been deleted and one substance has been changed.
  15. General Information: Chemical Substance Name
       907 Substances have been added and 2,098 substances have been changed.
  16. General Information: Structure and Data for structure search
       Structures for 665 substances have been added and 2,036 substances have been changed.
       201 Data for structure search have been added.

Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 34 KB].

*European Union : Risk Assessment Reports (EU : RAR)
Recently, website of the Risk Assessment Report (EU : RAR) has been changed from European Chemical Substances Information System (ESIS) to the European Chemicals Agency (ECHA). Since "Details" on CHRIP is linked to ESIS, which no longer work. We are currently working to change the linked URL of the Risk Assessment Report to ECHA. Thank you for your patience. For full text of the report, please visit the Existing Substances Regulation (ESR) site of ECHA.

 October 28, 2014

Following data have been updated.
  1. REACH : Substances of Very High Concern (SVHC)
       9 Substances have been added for Authorisation List based on the data of 2014/8/19 updated.
  2. Toxic Substances Control Act (TSCA): Significant New Use Rules (SNUR)
       34 Rules have been added based on 2014/9/8 effectuation.
  3. Korea: Toxic Chemicals Control Act (As of September 2014)
       10 Substances of Observational Chemicals have been added.
  4. US National Toxicology Program (NTP) Long-Term Study Reports (April 12, 2013)
       2 Abstracts were revised to a full report respectively based on a list of 2014/9/8 publication.
  5. International Agency for Research on Cancer (IARC)
       Based on a list of 2014/7/25 publication, 1 substance has been added, 4 substances have been changed in carcinogenicity classifications and 20 substances have been changed in evaluation YEAR.
  6. European Union (EU) : Carcinogen Risk Assessment
       Classification of substances have been updated based on 4-6th ATP (Adaptation to Technical Progress) of the Regulation (EC) No.1272/2008 on the classification, labelling and packaging of substances and mixtures (CLP Regulation).
  7. General Information: Chemical Substance Name
       515 Substances have been added and 489 substances have been changed.
  8. General Information: Structure and Data for structure search
       Structures for 105 substances have been added.
       108 Data for structure search have been added.

Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 12 KB].

 October 1, 2014

Following data have been updated.
  1. Chemical Substances Control Law : Rescission of Priority Assessment Chemical Substances (Public Notice 2014/10/1)
       5 Substances have been deleted.
  2. Chemical Substances Control Law : Newly Announced Chemical Substances prescribed in Paragraph (4) of Article 4 of the Former Act
       Confirmed link between Newly Announced Chemical Substances and CAS Registry Number : One Substance has been deleted.
  3. Chemical Substances Control Law : Biodegradation and Bioconcentration Results
    • Evaluation results of Newly Announced Chemical Substances and degradation products (Published 2014/7/31)
      348 substances have been added.
    • Confirmed links between published evaluation results and CAS Registry Number
      279 substances have been added, 6 substances have been changed.
  4. Poisonous and Deleterious Substances Control Act
       Confirmed links between substances of Poisonous and Deleterious Substances Control Act and CAS Registry Number: 810 substances have been added.
  5. General Information: Chemical Substance Name
       3 Substances have been added, one substance has been changed and one substance has been deleted.

Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 27 KB].

 September 11, 2014

Following data have been updated.
  1. Chemical Substances Control Law : Newly Announced Chemical Substances prescribed in Paragraph (4) of Article 4 of the Former Act
       Chemical names for 3 Newly Announced Chemical Substances have been updated based on the errata of official gazette.
  2. Chemical Substances Control Law : Other Relevant Information
       The results of screening assessment of chemical substances under Chemical Substances Control Law (CSCL) have been added for 9,965 substances.
  3. Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
       2 Exemplified substances have been added to "vanadium compound" of government ordinance number 321.
  4. Poisonous and Deleterious Substances Control Act
       3 Substances have been added and Cabinet Order Numbers of 9 Substances have been changed. (Public Notice 2014/6/25)
       Confirmed links between substances of Poisonous and Deleterious Substances Control Act and CAS Registry Number has been changed. Please see the updated information on October 1.
  5. Industrial Safety and Health Act : Relevant Ordinances
       1 Exemplified substance of Dangerous Substances and 2 exemplified substances of Specified Chemical Substances have been deleted.
  6. Air Pollution Control Law : Hazardous Air Pollutants
       2 Exemplified substances have been added to "vanadium and its compound" of report mention number 166 of the Central Environmental Council.
  7. Soil Contamination Countermeasures Act
       Soil leachate standard of 1 substance has been changed. (Public Notice 2014/8/1)
  8. General Information: Chemical Substance Name
       36 Substances have been added and 979 substances have been changed
  9. General Information: Structure and Data for structure search
       Structures for 981 Substances have been added.
       974 Data for structure search have been added.
  10. REACH : Substances of Very High Concern (SVHC)
       4 Substances have been added for Candidate List based on the data of 2014/6/16 updated.
  11. Toxic Substances Control Act (TSCA) : Significant New Use Rules (SNUR)
       28 Rules have been changed based on 2014/8/18 effectuation.
  12. Korea:Toxic Chemicals Control Act (As of July 2014)
       2 Substances of Prohibited Chemicals have been added.
  13. US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
       Draft reports of 1 substance have been added based on the data of 2014/6/28 updated.
  14. Results of Eco-toxicity tests of chemicals conducted by Ministry of the Environment in Japan
       5 Substances have been added based on the data published in March 2014.

   Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 66 KB].

 August 7, 2014

Following data have been updated.
  1. Chemical Substances Control Law : Newly Announced Chemical Substances prescribed in Paragraph (4) of Article 4 of the Former Act (Public Notice 2014/7/31)
       273 Substances have been added.

No CAS number was added by this update.

 July 17, 2014

Following information has been added newly.
  1. Chemical Substances Control Law : Other Relevant Information
       The results of screening assessment of chemical substances under Chemical Substances Control Law (CSCL) and the results of Japan HPV Challenge Program.
       The results of screening assessment of chemical substances will be posted on the next update.
  2. Industrial Safety and Health Act : Relevant Ordinances
    • Regulated dangerous or toxic substances (Dangerous Substances, Specified chemical substances, Lead, etc., Tetraalkyl lead, etc. and Organic solvents) are listed in the appended tables of Enforcement Order of Industrial Safety and Health Act.
    • Administrative control levels provided in the attached table of "Working Environment Evaluation Standards".

Key changes in the system are as follows.
  1. Chemical Substances Control Law : Toxicity Test Results
       Link for Details has been changed to J-CHECK (Japan CHEmicals Collaborative Knowledge database) from the National Institute of Health Sciences (NIHS).
  2. Viet Nam : Chemicals Control Act
       List by category of regulation has been changed into one list.
  3. System of search by structure has been changed as follows.
       Structure drawing tool : only "JavaApplet" is usable.
       Structure file t : only "MOL(.mol)" is usable.
       Similar type of search t : only "Tanimoto" is usable.

Following data have been updated.
  1. European Union (EU) : Carcinogen Risk Assessment
       Classification of substances have been changed to Annex VI of the Regulation (EC) No. 1272/2008 on the classification, labelling and packaging of substances and mixtures (CLP Regulation)

Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 776 KB].

 June 24, 2014

Following data have been updated.

(1)  Chemical Substances Control Law : Newly Announced Chemical Substances prescribed in Paragraph (4) of Article 4 of the Former Act
   Chemical names for 3 Newly Announced Chemical Substances have been updated based on the announcements of Ministry of Economy, Trade and Industry released on 2013/8/10, 2013/10/15 and 2014/1/17 in the METI?fs homepage (only available in Japanese).
(2)  Chemical Substances Control Law
   Typographical errors of Published Chemical Name have been corrected.
  • Monitoring Chemical Substances
  • Priority Assessment Chemical Substances
  • Newly Announced Chemical Substances prescribed in Paragraph (4) of Article 4 of the Former Act
  • Existing Chemical Substances
  • Type II Monitoring Chemical Substances (before amendment), Type III Monitoring Chemical Substances (before amendment)

(3)  Poisonous and Deleterious Substances Control Act : Confirmed links between substances of Poisonous and Deleterious Substances Control Act and CAS Registry Number have been updated. 947.   
June 25, 2014 There is error in the part of this data, we have now withdrawn for confirmation.
(4)  General Information: Chemical Substance Name
   943 Substances have been added and 1,063 substances have been changed.
(5)  General Information: Structure and Data for structure search
   Structures for 1,819 Substances have been added and 1 structure has been changed.
  1,591 Data for structure search have been added and 1 has been changed.
(6)  International Agency for Research on Cancer (IARC)
   Based on a list of 2014/3/31 publication, year or Vol. No. of 41 substances have been changed.
(7)  Chemical Substances Control Law: Toxicity test results of existing chemical substances
   20 Substances have been added based on the data of 2014/3 publication.
(8)  Toxic Substances Control Act (TSCA) : List of Existing Chemicals & Significant New Use Rules (SNUR)
  • List --- 65 Substances have been added and 1 substance have been deleted based on a list of 2014/2/24 publication.
  • SNUR --- 27 Rules have been added up to 2014/4/14 effectuation.

(9)  Results from MOE Report on Environmental Survey and Wildlife Monitoring of Chemicals
   Data of approximately 100 substances have been added based on the data of 2014/3 publication.
(10)  Australia : Priority Existing Chemicals (PEC) Assessment Reports by the National Industrial Chemicals Notification and Assessment Scheme (NICNAS)
   One Substance has been added. (May 2014)
(11)  US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts
   Draft reports of 7 substances have been added based on the data of 2014/4/11 updated.
(12)  Results of Eco-toxicity tests of chemicals conducted by Ministry of the Environment in Japan
   14 Substances have been added based on the data of 2014/3 publication.

   Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 87 KB].

 May 7, 2014

Following data have been updated.

(1)  Chemical Substances Control Law : Specified Chemical Substances (Enforced 2014/5/1)
   2 Substances have been added.
(2)  Chemical Substances Control Law : Monitoring Chemical Substances (Public Notice 2014/5/1)
   One Substance has been deleted.
(3)  Chemical Substances Control Law : Priority Assessment Chemical Substances (Public Notice 2014/4/1)
   13 Substances have been added and 4 Substances have been deleted.
(4)  Chemical Substances Control Law : Confirmed links between Existing Chemical Substances (MITI Number) and CAS Registry Number.
   5 Substances have been added and 27 Substances have been deleted.
(5)  Chemical Substances Control Law : Confirmed links between Not Regarded as a New Chemical Substance and CAS Registry Number.
   6 Substances have been added and 3 Substances have been changed.
(6)  Chemical Substances Control Law : Biodegradation and Bioconcentration Results
  • 79 Evaluation results have been added.
  • 212 Evaluation results (Published 2014/3/25) of Newly Announced Chemical Substances (Public Notice 2012/7/31) and degradation products have been added.

(7)  Industrial Safety and Health Act : Permission for Manufacturing
   Confirmed links between substances of Permission for Manufacturing and CAS Registry Number have been added. 17 CAS Registry Number have been added.
(8)  Industrial Safety and Health Act : Labeling, etc.
   Confirmed links between substances of Labeling, etc. and CAS Registry Number have been updated. 312 CAS Registry Number have been added, 9 CAS Registry Number have been changed and 2 CAS Registry Number have been deleted.
(9)  Industrial Safety and Health Act : Deliver of Documents, etc.
   Confirmed links between substances of Deliver of Documents, etc. and CAS Registry Number have been updated. 917 CAS Registry Number have been added, One CAS Registry Number has been changed and 5 CAS Registry Number have been deleted.
(10)  Act on the Prohibition of Chemical Weapons and the Control, etc. of Specific Chemicals
   3 Substances have been added.
(11)  Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof
   PRTR amounts of releases & transfers of up to 2012 (Published 2014/3/6) have been updated.
(12)  General Information: Structure
   1,494 Substances have been added.
(13)  General Information: Chemical Substance Name
   710 Substances have been added and 787 substance have been changed.

   Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 140 KB].

 March 24, 2014

Following data have been updated.

(1)  Chemical Substances Control Law : Chemical Substances exempt from notification of manufacturing/import amount (Public Notice March 24, 2014) have been updated.   
(2)  Confirmed links between the Reference Number by Category in The Gazette List of Existing Chemical Substances (MITI Number) and CAS Registry Number.
   5 Substances have been added, 7 Substances have been changed and 6 Substances have been deleted.
(3)  Chemical Substances Control Law: Biodegradation and Bioconcentration Results
   Confirmed links between published evaluation results and CAS Registry Number have been added.
(4)  Water Pollution Control Law and Soil Contamination Countermeasures Act
   Exemplary substances have been added.
(5)  TSCA : Significant New Use Rules (SNUR) (December 23, 2013)
   One new rule has been added.
(6)  Chemical Substances Control Law: Annual amounts of manufacture and import
   FY2012 Data have been added.
(7)  General Information: Structure
   1,500 Substances have been added.
(8)  General Information: Chemical Substance Name
   911 Substances have been updated and 589 Substances have been changed.

   Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 85KB].*April 1, 2014 CAS Registry Numbers list have been corrected.

 February 13, 2014

Following data have been updated.

(1)  Chemical Substances Control Law : Newly Announced Chemical Substances prescribed in Paragraph (4) of Article 4 of the Former Act
   One Chemical Substance Name of Newly Announced Chemical Substances (Public Notice 2013/07/31) has been changed for official gazette errata on 2013/12/16.
(2)  Confirmed links between the Reference Number by Category in The Gazette List of Existing Chemical Substances (MITI Number) and CAS Registry Number.
   190 Substances have been added, 4 Substances have been changed and 14 Substances have been deleted.
(3)  Chemical Substances Control Law : Biodegradation and Bioconcentration Results
  • 276 Evaluation results of Newly Announced Chemical Substances (Public Notice 2013/07/31) and degradation products (Published 2013/12/05) have been added.
  • 119 Analogy evaluation results have been added.
  • Confirmed links between published evaluation results and CAS Registry Number have been added.

(4)  Industrial Safety and Health Act : Tests Results of Mutagenicity of Existing Chemical Substances
   6 Substances have been added and One Substance has been deleted.
(5)  REACH : Substances of Very High Concern for Authorisation
   7 Substances have been added.
(6)  Toxic Substances Control Act (TSCA) : List of Existing Chemicals
   88 Substances have been added and 28 Substances have been changed.
(7)  Rotterdam Convention on the Prior Informed Consent (PIC) procedure for certain hazardous chemicals and pesticides in international trade
   56 Substances have been added.
(8)  International Chemical Safety Cards (ICSC)
   One Substance has been added.
(9)  Australia : Priority Existing Chemicals (PEC) Assessment Reports by the National Industrial Chemicals Notification and Assessment Scheme (NICNAS) (January 2014)
   One Substance has been added.
(11)  General Information: Chemical Substance Name
   7 Substances have been updated and One substance has been changed.

   Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 89KB].*May 7, 2014 CAS Registry Numbers list have been corrected.

 December 20, 2013

Following data have been updated.

(1)  Chemical Substances Control Law : Priority Assessment Chemical Substances (Public Notice December 20, 2013)
   22 Substances have been added and 2 Substances have been deleted.
(2)  Confirmed links between the Class Reference Number in The Gazette List (MITI Number) and CAS Registry Number.
   197 Substances have been changed and One Substance has been deleted.
(3)  UN Number and UN Hazard Class (18th Revised Edition, 2013)
   20 Data (20 Substances) have been added and 15 Data (8 Substances) have been changed.
(4)  TSCA : Significant New Use Rules (SNUR) (November 5, 2013)
   42 Substances have been added, 6 Substances have been changed and One Substance has been deleted.
(5)  Korea: Toxic Chemicals Control Act (November 2013)
   Observational Chemicals: 12 Substances have been added, One Substance has been changed and One Substance has been deleted.    Restricted Chemicals: 29 Substances have been added.
(6)  Concise International Chemical Assessment Documents (CICADs) (No.1-78)
   One Data has been added.
(7)  Environmental Health Criteria (EHC) (No. 243, 2013)
   One Substance has been added.
(8)  US Environmental Protection Agency : Integrated Risk Information System (IRIS) (September 30, 2013)
   2 Substances have been revised.
(9)  Australia : Priority Existing Chemicals (PEC) Assessment Reports by the National Industrial Chemicals Notification and Assessment Scheme (NICNAS) (November 2013)
   One Substance has been added.
(10)  International Agency for Research on Cancer (IARC): Carcinogen Risk Assessment (October 30, 2013)
   2 Substances have been added.
(11)  General Information: Chemical Substance Name
   9 Substances have been updated and One substance has been deleted.
(12)  Chemical Substances Control Law : Annual amounts of manufacture and import
   The display formats of the data of General Chemical Substance have been changed.

   Regarding CAS Registry Numbers for Chemical Substances that have been added, changed or deleted, please refer to the attachment[PDF markPDF 54KB].

 October 16, 2013

1. Data Updated.
(1)  Chemical Substances Control Law : Relations between Class Reference No. in The Gazetted List (MITI Number) and CAS Registry Number.
   786 Substances have been added, 127 Substances have been changed and 31 Substances have been deleted.
(2)  Chemical Substances Control Law : Newly Announced Chemical Substances prescribed in Paragraph (4) of Article 4 of the Former Act
   269 English names have been added.
(3)  Poisonous and Deleterious Substances Control Act(June 28, 2013)
   5 Substances have been added and Cabinet Order Numbers of 13 Substances have been changed.
(4)  Industrial Safety and Health Act : Labeling, etc.(August 13, 2013)
   One Substance has been added.
(5)  REACH: Substances of Very High Concern for Candidate List
   12 Data (2 Substances) have been added.
(6)  TSCA: SNUR(Significant New Use Rules)
   In case of comprehensive substance name, that name have been attached in front of individual substances name.
(7)  Rotterdam Convention on the Prior Informed Consent (PIC) procedure for certain hazardous chemicals and pesticides in international trade (August 10, 2013)
   18 Data (4 Substances) have been added.
(8)  US Agency for Toxic Substances and Disease Registry (ATSDR): Toxicological Profiles (August 27, 2013)
   4 Substances have been added.
(9)  Canadian Environmental Protection Act (CEPA) - Priority Substances Assessment Program : Priority Substances List (PSL)
   The page address of the link destination have been changed.
(10)  US Environmental Protection Agency : Integrated Risk Information System (IRIS) (August 27, 2013)
   One Substance's name and review has been revised.
(11)  US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts (August 27, 2013)
   One Abstract has been revised to a full text.
(12)  International Agency for Research on Cancer (IARC): Carcinogen Risk Assessment (July 16, 2013)
   By reflection to July 16, 2013 (vol.1 - 108), 13 substances have been added and 1 substance has been changed, and by review of the monograph 127 substances have been added.
(13)  US Environmental Protection Agency (EPA) : Carcinogen Risk Assessment (August 27, 2013)
   One Substance has been changed in the classification of carcinogenicity.
(14)  Results from MOE's Report on Environmental Survey and Monitoring of Chemicals (Sep. 2013)
   7 Data (1 Substances) have been added and 2 Data (2 Substances) have been changed.
(15)  General Information: Chemical Substance Name
   53 Substances have been updated.

2. List of Update
   CAS Registry Numbers for Chemical Substances have been added, changed or deleted in above 1.
   Please refer to the attachment[PDF markPDF 125KB]. *March 24, 2014 CAS Registry Numbers list have been corrected.

 July 31, 2013 

The following information has been newly added.

  • Chemical Substances Control Law : Chemical Substances exempt from notification of manufacturing / import amount / March 22, 2013
The following data has been updated.

Data / Published Date
  • Chemical Substances Control Law: Chemical Substances Relating to a Public Notice Pursuant to The Provisions of Paragraph 4 of Article 4 of the Former Act / July 31, 2013
  • UN Number and UN Hazard Class (4 Substances have been deleted)
  • REACH: Substances of Very High Concern for Candidate List / June 20, 2013
  • TSCA: SNUR(Significant New Use Rules) / May 31, 2013
  • GHS Classification Results by Japanese Government / July 18, 2013
  • Agency for Toxic Substances and Disease Registry (ATSDR): Toxicological Profile (364 Substances have been added)
  • Results of Eco-toxicity tests of chemicals conducted by Ministry of the Environment in Japan / March. 2013
  • Ministry of Economy, Trade and Industry (METI) Safety Test (59 Data have been added)
  • Results from MOE Report on Environmental Survey and Wildlife Monitoring of Chemicals / March. 2013
  • General Information: Structure (55 Substances have been updated)
  • General Information: Chemical Substance Name (57 Substances have been updated)

 June 13, 2013 

The following data has been updated.

Data / Published Date
  • Confirmed links between the Reference Number by Category in The Gazette List of Existing Chemical Substances (MITI Number) and CAS Registry Number
  • Toxicity Tests on Existing Chemicals under the Chemical Substances Control Law / March, 2013
  • Biodegradation and Bioconcentration of Existing Chemical Substances under the Chemical Substances Control Law link to J-CHECK
  • REACH: Substances of Very High Concern for Authorisation List / April 18, 2013
  • TSCA/SNUR(Significant New Use Rules) / Feb. 12, 2013
  • Agency for Toxic Substances and Disease Registry (ATSDR) Toxicological Profiles / March 5, 2013
  • International Chemical Safety Cards (ICSCs) / June, 2012
  • US National Toxicology Program (NTP) Long-Term Study Reports / April 12, 2013
  • Results of Eco-toxicity tests of chemicals conducted by Ministry of the Environment in Japan / March, 2013
  • International Agency for Research on Cancer (IARC): Carcinogen Risk Assessment / April 10, 2013
  • Ministry of Economy, Trade and Industry (METI) Safety Test (36 Substances were added)

 April 25, 2013 

The following new information has been newly added.

  • Chemical Substances Control Law : Annual amounts of manufacture and/or import, etc. reported under Act on the Evaluation of Chemical Substances and Regulation of Their Manufacture, etc. / 2010 and 2011
  • Thailand : Hazardous Substances Act (Jurisdiction of the Ministry of Industry, Department of Industrial Works) / Jan. 29, 2009
  • Link to Summary of Initial Risk Assessment Reports
The following data has been updated.

Data / Published Date
  • Confirmed links between the Reference Number by Category in The Gazette List of Existing Chemical Substances (MITI Number) and CAS Registry Number
  • Chemical Substances Control Law: Existing Chemical Substances (2 substances were deleted)
  • Industrial Safety and Health Act (MSDS required) / Oct. 1, 2012
  • PRTR amounts of releases & transfers / Feb. 28, 2013
  • TSCA:SNUR (Significant New Use Rules) / February 19, 2013
  • Ministry of Economy, Trade and Industry (METI) Safety Test (12 Substances were added)

 Mar. 26,2013 

The following new information has been newly added.

  • Poisonous and Deleterious Substances Control Law / September 21 , 2012
  • Act on the Prohibition of Chemical Weapons and the Regulation of Specific Chemicals / February 29 , 2012
  • Ministry of Economy, Trade and Industry (METI) Safety Test
The following data has been updated.

Data / Published Date
  • Chemical Substances Control Law: Type II Monitoring Chemical Substances (before amendment), Type III Monitoring Chemical Substances (before amendment)
  • Chemical Substances Control Law: Priority Assessment Chemical Substances / March 22 , 2013
  • Chemical Substances Control Law: Chemical Substances Relating to a Public Notice Pursuant to The Provisions of Paragraph 4 of Article 4 of the Former Act / February 21, 2013
  • Confirmed links between the Reference Number by Category in The Gazette List of Existing Chemical Substances (MITI Number) and CAS Registry Number
  • Chemical Substances Control Law: Toxicity test results of existing chemical substances / April , 2012
  • Industrial Safety and Health Act :Labeling required /September 20, 2012
  • Industrial Safety and Health Act :Result of Mutagenicity Tests / December 11, 2012
  • REACH: Substances of Very High Concern for Authorisation Candidate List /December 19, 2012
  • TSCA/SNUR(Significant New Use Rules) / December 31, 2012
  • US National Toxicology Program (NTP) Long-Term Study Reports TR Abstracts / February 4, 2013

 Feb. 15,2013 

The following new information has been newly added .

  • Indonesian Government Regulation No. 74/2001 on Management of Hazardous and Toxic Substances
The following data has been updated.

Data / Published Date
  • Modification of Chemical Substances Control Law: Existing Chemical Substances
  • Chemical Substances Control Law: Not Regarded as a New Chemical Substance(Modification due to the publication of the Priority Assessment Chemical Substances of December 21, 2012)
  • TSCA/SNUR(Significant New Use Rules) / November 20 & December 4, 2012
  • Stockholm Convention on Persistent Organic Pollutants (POPs) / October 27,2012
  • International Agency for Research on Cancer (IARC): Carcinogen Risk Assessment / November 7, 2012

 Dec. 26,2012 

The following data has been updated.

Data / Published Date
  • Chemical Substances Control Law: Priority Assessment Chemical Substances / Dec. 21, 2012

 Dec. 4,2012 

The following information has been added newly.

  • REACH: Substances of Very High Concern for Authorisation (Annex XIV: Authorisation List)
  • Korea: Toxic Chemicals Control Act (Observational Chemicals, Restricted Chemicals, Prohibited Chemicals, Accident Precaution Chemicals)
The information that was temporarily unavailable has been updated and listed once again.

  • REACH : Substances of Very High Concern for Authorisation ( Candidate List)
The following data has been updated.

Data / Published Date
  • Significant New Use Rule (TSCA) / Oct 15, 2012
  • Priority Existing Chemicals (PEC) Assessment Reports , the National Industrial Chemicals Notification and Assessment Scheme (NICNAS) / Sep, 2012
  • US National Toxicology Program (NTP) Long-Term Study Reports TR Abstracts / Sep 14, 2012
  • International Agency for Research on Cancer (IARC): Carcinogen Risk Assessment / Aug 7, 2012
  • European Union (EU): Carcinogen Risk Assessment / July 11, 2012

 Nov. 12,2012 

The following data has been updated.

Data / Published Date
  • US National Toxicology Program (NTP) Long-Term Study Reports TR Abstracts / July 25, 2012
  • TSCA/SNUR(Significant New Use Rules) / July 25, 2012
  • International Chemical Safety Cards (ICSCs) / Jun 27. 2012

 Oct. 3,2012 

The following data is not displayed due to the recent malfunction of J-CHECK.

  • All links to J-CHECK are deleted.

 Sep. 3,2012 

The following data has been updated.

  • Chemical Substances Control Law: New Chemical Substances Prescribed in a Public Notice Pursuant to The Provisions of Paragraph (4) of Article 4 of the Former Act (250 English names added)

 July 31,2012 

The following data has been updated.

Data / Published Date
  • Chemical Substances Control Law: Chemical Substances Relating to a Public Notice Pursuant to The Provisions of Paragraph 4 of Article 4 of the Former Act (July 31, 2012)
  • Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof(Confirmed links between the Cabinet Order No. and CAS Registry Number)
  • Industrial Safety and Health Act: Mutagenicity Test Data of Existing Chemical Substance(2 Substances were added)
  • Air Pollution Control Law (Hazardous Air Pollutants) / October 15, 2010
  • TSCA/SNUR(Significant New Use Rules) / June 26, 2012
  • Priority Existing Chemical(PEC) Assessment Reports / June, 2012
  • Results of Eco-toxicity tests of chemicals conducted by Ministry of the Environment in Japan / March, 2012
  • NITE Toxicity Test (Study Reports were linked from reference of PDF files)

 July 2,2012  

The following data has been updated.

Data / Published Date
  • Water Pollution Control Law / May 23, 2012
  • The results of Chemicals in the Environment-Report on Environmental Survey and Wildlife Monitoring of Chemicals by the Ministry of the Environment / 2010
  • The Rotterdam Convention on the prior informed consent procedure for certain hazardous chemicals and pesticides in international trade (PIC) / Oct. 24, 2011
  • International Agency for Research on Cancer (IARC): Monographs on the evaluation of Carcinogenic Risks to Humans. Vol.104 /Mar. 27, 2012

 Apr. 26,2012  

The following data has been updated.

  • Confirmed links between the Reference Number by Category in The Gazette List of Existing Chemical Substances (MITI Number) and CAS Registry Number
 Mar. 29,2012 

The display format of the "Chemical Substances Control Law"on the Comprehensive Information has been changed in order of articles of the law.

The following information has been added newly.

Data / Published Date
  • Chemical Substances Control Law: Priority Assessment Chemical Substances "Reason for Inclusion"
  • Chemical Substances Control Law: Not Regarded as a New Chemical Substance "Classification of Related Chemical Substance"
  • Information on result of the GHS classification / Mar. 2, 2012
  • Vietnam: Decree No. 108/2008/ND-CP Detailing and Guiding the Implementation of a Number of Articles of the Chemical Law / Oct. , 2008
The following data has been updated.

Data / Published Date
  • Chemical Substances Control Law: Monitoring Chemical Substances / Mar. 22, 2012
  • Chemical Substances Control Law: Priority Assessment Chemical Substances / Mar. 22, 2012 and Mar. 23, 2012
  • Chemical Substances Control Law: Substances not Requiring Notification / Mar. 22, 2012
  • Chemical Substances Control Law: Newly confirmed links between Class Reference Number in The Gazetted List (MITI No.) and CAS Registry No.
  • Water Pollution Control Law: Examples of each chemicals included in groups of compounds added
  • TSCA Inventory / Jan. 2012
  • Law concerning Pollutant Release and Transfer Register (PRTR): PRTR amounts of releases & transfers / Mar. 13, 2012
  • Integrated Risk Information System (IRIS), U.S. Environmental Protection Agency / Feb. 21, 2012
  • Environmental Protection Agency (EPA): Carcinogen Risk Assessment / Feb. 21, 2012
  • Data for Structural Search (Data for 683 substances added, total for 22,000 substances)
  • Image of Structural Formula (Images for 647 substances added, total for 24,000 substances)

 Feb. 29,2012 

The following data has been updated.

Data / Published Date
  • Chemical Substances Control Law: Chemical Substances Relating to a Public Announcement under The Provisions of Paragraph 4 of Article 4 of the Former Act / Feb. 20, 2012
  • International Chemical Safety Cards (ICSCs) / Dec. 2011
  • Integrated Risk Information System (IRIS), U.S. Environmental Protection Agency / Feb. 10, 2012
  • U.S. National Toxicology Program (NTP) Long-Term Study Reports TR Abstracts / Dec. 2011 (2 reports added)
  • Environmental Protection Agency (EPA): Carcinogen Risk Assessment / Feb. 10, 2012

 Jan. 31,2012 

The following data has been updated.

Data / Published Date
  • Industrial Safety and Health Act (Result of Mutagenicity Tests) / Nov. 2011
  • REACH Candidate List of Substances of Very High Concern for Authorisation / Dec. 19, 2011
  • Significant New Use Rule (TSCA) / Dec. 5, 2011
  • OECD HPV Program / Nov. 2011
  • Integrated Risk Information System (IRIS), U.S. Environmental Protection Agency / Nov. 18, 2011
  • Priority Existing Chemicals (PEC) / Nov. 2011
  • National Toxicology Program (NTP) Long-Term Study Reports TR Abstracts / Dec. 2011
  • Environmental Protection Agency (EPA): Carcinogen Risk Assessment / Nov. 18, 2011

 Nov. 30,2011 

The following data has been updated.

Data / Published Date
  • Water Pollution Control Law / Oct. 28, 2011
  • UN No. and Classification (Rev.17) / 2011
  • Toxic Substances Control Act (TSCA) Inventory / Sep. 2011
  • US National Toxicology Program (NTP) Long-Term Study Reports TR Abstracts / Oct. 2011
The links to the published data of 'Biodegradation and Bioconcentration of Existing Chemical Substances under the Chemical Substances Control Law' have changed to J-CHECK (http://www.safe.nite.go.jp/jcheck/english/).

 Oct. 31,2011 

The following data has been updated.

  • Chemicals in the Environment -Report on Environmental Survey and Wildlife Monitoring of Chemicals.(Listed:up to 2009)
  • Integrated Risk Information System (IRIS) of US Environmental Protection Agency (EPA). Sep/30/2011
  • Environmental Protection Agency (EPA):Evidence for Human Carcinogenicity. Sep/30/2011
  • Physical and Chemical Properties.(Add 8 Chemical Substances)

 Sep. 29,2011 

The following data has been updated.

  • Integrated Risk Information System (IRIS) of US Environmental Protection Agency.  7/13/2011
  • Environmental Protection Agency (EPA):Evidence for Human Carcinogenicity.  7/13/2011
  • International Agency for Research on Cancer (IARC): Monographs on the evaluation of Carcinogenic Risks to humans. Vol.102