Herbimycin A : Cluster information
Compound
| Entry name | Herbimycin A |
|---|---|
| PKS Type | TypeI modular |
| Starter Unit | 3-amino-5-hydroxybenzoic acid (AHBA) |
| Chain Length | 8 |
| Sugar Unit | none |
| Classification | Ansamycin |
| Activity | Antitumor |
| Composition | C30H42N2O9 |
Original source
| Organism | Streptomyces hygroscopicus |
|---|---|
| Strain | AM 3672 |
| Contig | AY947889 |
PKS/NRPS Module
| Herb_00170 hbmAI | 0 |  | |
| 1 |  | methylmalonyl-CoA | |
| 2 | | methoxymalonyl-ACP | |
| 3 |  | methylmalonyl-CoA | |
| Herb_00180 hbmAII | 4 |  | methylmalonyl-CoA |
| 5 | | methoxymalonyl-ACP | |
| Herb_00190 hbmAIII | 6 | | malonyl-CoA |
| 7 | | methylmalonyl-CoA |
Reference
- Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption.
- Rascher A, Hu Z, Buchanan GO, Reid R, Hutchinson CR[PMID: 16085885]Appl Environ Microbiol. 71 (2005) 4862-71
Data download
| Compound name | Genomic nucleotide sequence |
Nucleotide sequences of the coding regions | Translation of the coding sequences | List of genes/ORFs | GBK | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
 Herbimycin A |
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History
- 2013-01-16[Update]
- 2012-08-03[Update]
- 2012-03-28[Release]
