Halstoctacosanolide : Cluster information
Compound
| Entry name | Halstoctacosanolide |
|---|---|
| PKS Type | TypeI modular |
| Starter Unit | methylmalonyl-CoA |
| Chain Length | 19 |
| Sugar Unit | none |
| Classification | Other Macrocyclic Lactone |
| Activity | Antibacterial |
| Composition | A: C48H76O12 |
Original source
| Organism | Streptomyces halstedii |
|---|---|
| Strain | HC34 |
| Contig | AB241068 |
PKS/NRPS Module
| Halsto_00010 hlsA | 0 |  | methylmalonyl-CoA |
| 1 |  | methylmalonyl-CoA | |
| 2 | | malonyl-CoA | |
| Halsto_00020 hlsB | 3 | | malonyl-CoA |
| 4 |  | methylmalonyl-CoA | |
| 5 |  | methylmalonyl-CoA | |
| 6 | | malonyl-CoA | |
| Halsto_00030 hlsC | 7 | | methylmalonyl-CoA |
| 8 | | malonyl-CoA | |
| 9 | | malonyl-CoA | |
| Halsto_00040 hlsD | 10 | | methylmalonyl-CoA |
| 11 |  | malonyl-CoA | |
| 12 | | malonyl-CoA | |
| Halsto_00050 hlsE | 13 | | methylmalonyl-CoA |
| 14 | | malonyl-CoA | |
| Halsto_00060 hlsF | 15 | | methylmalonyl-CoA |
| 16 | | methylmalonyl-CoA | |
| 17 | | malonyl-CoA | |
| Halsto_00070 hlsG | 18 |  | methylmalonyl-CoA |
Reference
- The complete biosynthetic gene cluster of the 28-membered polyketide macrolactones, halstoctacosanolides, from Streptomyces halstedii HC34.
- Tohyama S, Kakinuma K, Eguchi T[PMID: 16568718]J Antibiot (Tokyo). 59 (2006) 44-52
Data download
| Compound name | Genomic nucleotide sequence |
Nucleotide sequences of the coding regions | Translation of the coding sequences | List of genes/ORFs | GBK | |||||||
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 Halstoctacosanolide |
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History
- 2012-03-28[Release]
