Nigericin : Cluster information
Compound
| Entry name | Nigericin |
|---|---|
| PKS Type | TypeI modular |
| Starter Unit | malonyl-CoA |
| Chain Length | 15 |
| Sugar Unit | none |
| Classification | Polyether |
| Activity | Antibacterial Ionophore |
| Composition | C40H68O11 |
Original source
| Organism | Streptomyces violaceusniger |
|---|---|
| Strain | DSM 4137 |
| Contig | DQ354110 |
PKS/NRPS Module
| Niger_00020 nigAI | 0 |  | malonyl-CoA |
| 1 |  | methylmalonyl-CoA | |
| Niger_00030 nigAII | 2 |  | methylmalonyl-CoA |
| Niger_00040 nigAIII | 3 |  | malonyl-CoA |
| 4 | | methylmalonyl-CoA | |
| Niger_00050 nigAIV | 5 | | methylmalonyl-CoA |
| 6 | | malonyl-CoA | |
| Niger_00060 nigAV | 7 | | methylmalonyl-CoA |
| 8 | | methylmalonyl-CoA | |
| Niger_00070 nigAVI | 9 |  | methylmalonyl-CoA |
| Niger_00170 nigAVII | 10 |  | malonyl-CoA |
| 11 | | malonyl-CoA | |
| 12 | | malonyl-CoA | |
| Niger_00160 nigAVIII | 13 | | methylmalonyl-CoA |
| Niger_00150 nigAIX | 14 | | methylmalonyl-CoA |
| Niger_00110 nigAX | 15 |  | |
| Niger_00100 nigAXI | 15 |  |
Reference
- Insights into polyether biosynthesis from analysis of the nigericin biosynthetic gene cluster in Streptomyces sp. DSM4137.
- Harvey BM, Mironenko T, Sun Y, Hong H, Deng Z, Leadlay PF, Weissman KJ, Haydock SF[PMID: 17584617]Chem Biol. 14 (2007) 703-14
Data download
| Compound name | Genomic nucleotide sequence |
Nucleotide sequences of the coding regions | Translation of the coding sequences | List of genes/ORFs | GBK | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
 Nigericin |
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History
- 2012-08-03[Update]
- 2012-04-26[Release]
