Steffimycin : Cluster information
Compound
Entry name | Steffimycin |
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PKS Type | TypeII |
Starter Unit | acetyl-CoA |
Chain Length | 10 |
Sugar Unit | 2-O-methyl-L-rhamnose |
Classification | Anthracycline |
Activity | Antitumor |
Composition | C28H30O13 |
Original source
Organism | Streptomyces steffisburgensis |
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Strain | NRRL 3193 (=NBRC 13446) |
Contig | AM156932 |
PKS/NRPS Module
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Reference
- Isolation, characterization, and heterologous expression of the biosynthesis gene cluster for the antitumor anthracycline steffimycin.
- Gullon S, Olano C, Abdelfattah MS, Brana AF, Rohr J, Mendez C, Salas JA[PMID: 16751529]Appl Environ Microbiol. 72 (2006) 4172-83
- Glycosylated derivatives of steffimycin: insights into the role of the sugar moieties for the biological activity.
- Olano C, Abdelfattah MS, Gullon S, Brana AF, Rohr J, Mendez C, Salas JA[PMID: 18224649]Chembiochem. 9 (2008) 624-33
Data download
History
- 2012-10-02[Release]