Tetronomycin : Cluster information
Compound
| Entry name | Tetronomycin |
|---|---|
| PKS Type | TypeI modular |
| Starter Unit | malonyl-CoA |
| Chain Length | 13 |
| Sugar Unit | none |
| Classification | Polyether Tetronic Acid Derivative |
| Activity | Antibacterial Ionophore |
| Composition | C34H50O8 |
Original source
| Organism | Streptomyces sp. |
|---|---|
| Strain | NRRL 11266 |
| Contig | AB193609 |
PKS/NRPS Module
| Tetrn_00070 tmnAI | 0 |  | malonyl-CoA |
| 1 |  | malonyl-CoA | |
| 2 |  | malonyl-CoA | |
| Tetrn_00140 tmnAII | 3 |  | malonyl-CoA not conserved HAFHS |
| Tetrn_00150 tmnAIII | 4 | | malonyl-CoA |
| 5 | | malonyl-CoA | |
| Tetrn_00160 tmnAIV | 6 | | methylmalonyl-CoA |
| 7 | | methylmalonyl-CoA | |
| 8 | | malonyl-CoA | |
| Tetrn_00170 tmnAV | 9 | | malonyl-CoA |
| 10 | | methylmalonyl-CoA | |
| 11 | | methylmalonyl-CoA | |
| Tetrn_00110 tmnAVI | 12 |  | malonyl-CoA |
Reference
- Glyceryl-S-acyl carrier protein as an intermediate in the biosynthesis of tetronate antibiotics.
- Sun Y, Hong H, Gillies F, Spencer JB, Leadlay PF[PMID: 18046685]Chembiochem. 9 (2008) 150-6
- Analysis of the tetronomycin gene cluster: insights into the biosynthesis of a polyether tetronate antibiotic.
- Demydchuk Y, Sun Y, Hong H, Staunton J, Spencer JB, Leadlay PF[PMID: 18404760]Chembiochem. 9 (2008) 1136-45
Data download
| Compound name | Genomic nucleotide sequence |
Nucleotide sequences of the coding regions | Translation of the coding sequences | List of genes/ORFs | GBK | |||||||
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 Tetronomycin |
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History
- 2013-05-28[Update]
- 2013-01-16[Update]
- 2012-06-04[Release]
