LOCUS       Doxorubicin            42203 bp	DNA     linear     22-Dec-2016
DEFINITION  Doxorubicin biosynthesis cluster
ACCESSION   Doxorubicin
VERSION
KEYWORDS
SOURCE      Streptomyces peucetius
FEATURES             Location/Qualifiers
     source          1..42203
                     /organism="Streptomyces peucetius"
                     /mol_type="genomic DNA"
                     /strain_name="ATCC 29050"
                     /db_xref="taxon:55158"
     CDS             655..1710
                     /locus_tag="Adria_00080"
                     /product="putative glucose-1-phosphate
                     thymidylyltransferase"
                     /note="original product:glucose-1-phosphate
                     thymidylyltransferase"
                     /note="product synonym:putative dTDP-glucose synthase"
                     /gene="dnmL"
                     /note="original gene:dnrL"
                     /note="category:2.3 modification addition of sugar moiety"
                     /EC_number="2.7.7.24"
                     /transl_table=11
                     /inferenece="InterPro:IPR005908"
                     /inferenece="InterPro:IPR005835"
                     /translation="MKALVLSGGSGTRLRPFTHTSPKQLVPVANKPVLYYVLEDIAQA
                     SITEVGIVVGETSNEIRKAVGSGDRFGLRVTYLPQEAPLGLAHAVLIARDYLGEEDFV
                     MYLGDNFVVGGIAGNSSTFRAERPDAQILLTRVSDPSSFGVAEIGCDGRVVALEEKPR
                     HPRSDLAVVGIYLFTPVVHEAVRALTPSRRGELEITDALQWLLDGPYDVRYTTISGYW
                     KDTGNVADMLEVNRAVLDGIEPGMEGQADAASELVGRVRIEAGAQIRASRIVARRHRA
                     GRVTDRTSALHVDRGDCSIETARSSLHHAGRLPAHGTRRVQHSLLGRNVTVAPAPRVP
                     AGSRLILGDDSRVEISS"
     CDS             1707..1892
                     /locus_tag="Adria_00090"
                     /product="putative dTDP-glucose 4,6-dehydratase(fragment)"
                     /gene="dnmM"
                     /note="original gene:dnrM"
                     /note="category:5.2 function unknown"
                     /transl_table=11
                     /inferenece="InterPro:IPR001509"
                     /inferenece="InterPro:IPR016040"
                     /translation="MTMKILVTGGAGFIGSHYVRALLGPRGDGSVGVTAGQPDLCRQS
                     GQPRSRPRRRAVRLRPR"
     CDS             complement(2725..3333)
                     /locus_tag="Adria_00100"
                     /product="LuxR family transcriptional activator"
                     /note="original product:regulatory protein"
                     /note="original gene:dnrN"
                     /note="category:4.1 transcriptional regulator"
                     /transl_table=11
                     /inferenece="InterPro:IPR011006"
                     /inferenece="InterPro:IPR000792"
                     /inferenece="InterPro:IPR016032"
                     /inferenece="InterPro:IPR011991"
                     /inferenece="InterPro:IPR001789"
                     /translation="MTIRVVIAEELEMVRAALVLLVERESDIKVVASTGVGSELIRTV
                     LEYSPDVTVIDVDMHEREGLLSAMAIQEHLPDCRTLLTARFARLATVRQSLASGLGGL
                     VLKSSPPAHLSDAIRSVHEGRRVFDTELTLAAWGNTGCPLTEREMEILQLAAAGDDIN
                     EIAVKLSLSPGTVRNYLATTVRKMDARNRLDAVRIASMSGWI"
     CDS             3767..4789
                     /locus_tag="Adria_00110"
                     /product="transcriptional activator/repressor"
                     /note="original product:putative repressor"
                     /note="original gene:dnrO"
                     /note="category:4.1 transcriptional regulator"
                     /transl_table=11
                     /inferenece="InterPro:IPR013196"
                     /inferenece="InterPro:IPR011991"
                     /inferenece="InterPro:IPR001034"
                     /inferenece="InterPro:IPR018356"
                     /translation="MTETPSRMLRLLSLLQNSRDWPGRKLAERLGVSPRTLRRDVERL
                     RDLGYPVQAIPGVGGGYRLEAGASLPPLLLDDDEAVAIAVGLRTAAGGSVADIEDTSI
                     RALAKLEQVLPKRLRSRVNALQMYTVPMFTVTPTVSPEHLASVAQACRDQQRLRFTYR
                     KRDGETSSRLVEPYRLVHVNRKWYVLSWDMGRQDWRTFRVDRMESLLLTGVRFQQREL
                     PAEDAAAYVAQSITSSLAGYRALVTLHAPVEVVAERIRPRDGILTAVDHRTCRLRSAA
                     DSLEWLALTIGMFGVEFEVHEPPELIHYIQELSERLARAASPGADRSVVAPPTRDAPV
                     SGPAAG"
     CDS             complement(5271..6740)
                     /locus_tag="Adria_00115"
                     /product="aklavinone C-11 hydroxylase"
                     /note="original product:aklavinone C-11 hydroxylase"
                     /note="original gene:dnrF"
                     /note="category:3.1 modification hydroxylation"
                     /transl_table=11
                     /inferenece="InterPro:IPR002938"
                     /inferenece="InterPro:IPR003042"
                     /translation="MALTKPDVDVLVVGGGLGGLSTALFLARRGARVLLVERHASTSV
                     LPKAAGQNPRTMELFRFGGVADEILATDDIRGAQGDFTIKVVERVGGRVLHSFAESFE
                     ELVGATEQCTPMPWALAPQDRVEPVLVAHAAKHGAEIRFATELTSFQAGDDGVTARLR
                     DLGTGAESTVSARYLVAADGPRSAIRESLGITRHGHGTLAHFMGVIFEADLTAVVPPG
                     STGWYYLQHPDFTGTFGPTDRPNRHTFYVATTPERGERPEDYTPQRCTELIRLAVDAP
                     GLVPDILDIQAWDMAAYIADRWREGPVLLVGDAAKVTPPTGGMGGNTAIGDGFDVAWK
                     LAAVLRGEAGERLLDSYGAERSLVSRLVVDESLAIYAQRMAPHLLGSVPEERGTAQVV
                     LGFRYRSTAVAAEDDDPEPTEDPRRPSGRPGFRAPHVWIEQDGTRRSTVELFGDCWVL
                     LAAPEGGAWPGRPPAPPRIWASASTSISSAAMSPPPPAN"
     CDS             7562..8554
                     /locus_tag="Adria_00130"
                     /product="multidrug resistance ABC transporter ATP-binding
                     protein"
                     /note="original product:daunorubicin resistance protein"
                     /note="original gene:drrA"
                     /note="category:4.3 transport"
                     /transl_table=11
                     /inferenece="InterPro:IPR017871"
                     /inferenece="InterPro:IPR003593"
                     /inferenece="InterPro:IPR003439"
                     /inferenece="InterPro:IPR005894"
                     /translation="MNTQPTRAIETSGLVKVYNGTRAVDGLDLNVPAGLVYGILGPNG
                     AGKSTTIRMLATLLRPDGGTARVFGHDVTSEPDTVRRRISVTGQYASVDEGLTGTENL
                     VMMGRLQGYSWARARERAAELIDGFGLGDARDRLLKTYSGGMRRRLDIAASIVVTPDL
                     LFLDEPTTGLDPRSRNQVWDIVRALVDAGTTVLLTTQYLDEADQLADRIAVIDHGRVI
                     AEGTTGELKSSLGSNVLRLRLHDAQSRAEAERLLSAELGVTIHRDSDPTALSARIDDP
                     RQGMRALAELSRTHLEVRSFSLGQSSLDEVFLALTGHPADDRSTEEAAEEEKVA"
     CDS             8551..9402
                     /locus_tag="Adria_00140"
                     /product="multidrug resistance ABC transporter permease
                     protein"
                     /note="original product:daunorubicin resistance protein"
                     /note="original gene:drrB"
                     /note="category:4.3 transport"
                     /transl_table=11
                     /inferenece="InterPro:IPR013525"
                     /inferenece="InterPro:IPR000412"
                     /translation="MTTSPGTVESTTPVSGQLRTVLSAGERPARATAVSATLTHLWRA
                     MMAFKHFPVQLIDIVLMPLIFLLMFTYLFGGAFADSTEEYLQFYLPGVTVQAVVMMTV
                     YTGTSLNTDIHKGVFDRFRTLPFWQPATLAGSLLGDVLRYVVALATTVSLGLLLGFRA
                     DGGFLGVVGAMLVLIVFGFSVSWIFAALGVVASEPERVSGTSMIVLYPLLFMSNIFVM
                     PETMPGWMQAIVDANPMSHAATASRELMHGTAGFWDVGLVLCVSAGLVAVFAPLTMRL
                     YRNKNAH"
     CDS             9454..9814
                     /locus_tag="Adria_00150"
                     /product="hypothetical protein(fragment)"
                     /note="category:5.4 hypothetical protein"
                     /transl_table=11
     CDS             complement(11079..11897)
                     /locus_tag="Adria_00160"
                     /product="cyclase"
                     /note="original product:polyketide cyclase"
                     /note="original gene:dpsY"
                     /note="category:3.4 other modification"
                     /transl_table=11
                     /inferenece="InterPro:IPR007325"
                     /translation="MCCGGPRGAEATTMRIIDISSAVDASGWEPDEVRHEVHSPREGA
                     VHMSEEMRRHFGVAFDPDELPEGEFLSLDRLTLTSHTGTHIDAPSHYGSRAHYGDGRP
                     RNIDELPLDWFYGPGLLLDLTGCDGPTAGAGDLEKELARIGRVPEPGTIVLLRTGASE
                     RAGTEQYFTDFTGLDGPAVNLLLDHGVRVIGTDAFSLDAPFGAVIRRYRETGDRSVLW
                     PAHVTGRHREYCQIERLGNLAALPGCDGFQVACFPVKITGGGAGWTRAVAFVDE"
     CDS             complement(9815..11026)
                     /locus_tag="Adria_00170"
                     /product="putative NDP-hexose C-3 C-methyltransferase"
                     /note="original product:daunorubicin/doxorubicin
                     biosynthesis enzyme"
                     /note="original gene:dnrX"
                     /note="category:5.1 general function"
                     /EC_number="2.1.1.-"
                     /transl_table=11
                     /inferenece="InterPro:IPR013691"
                     /inferenece="InterPro:IPR013630"
                     /translation="MEPNESTCRICGGRVREFFDFGRQPLSDYFPSEEELDNEFFFRL
                     AVGMCVTCTMVQLLEEVPRDRMFRYDYPYHSSGSERMREHFAATARRLIGTELTGRDP
                     FCVEIGSNDGVMLRTVRDAGVRHLGVEPSGGVADVSRAEGIQVRTAFFEESTAREIAQ
                     EHGPANVIYAANTICHIPYLDSVFRGIDALLAPDGVFVFEDPYLGDIVEKNTFDQIYD
                     EHFYLFTARSVSTTAQHFGFELVDVERLPVHGGEVRYTIARAGRRQPSPRVGELIAEE
                     SRRGLADLTTLEKFGAQVKRVCCDLVARLRELRDLGFYVVGYGATAKSATVLNYAGIG
                     PDLLPCVYDTTPAKIGRRLPGSHIPIRSAEEFRAPYPDYALLFAWNHLDEVQAREAEF
                     TKQGGRWIRSG"
     CDS             12060..13088
                     /locus_tag="Adria_00180"
                     /product="dTDP-L-epivancosamine nitrososynthase"
                     /note="original product:putative flavoprotein"
                     /note="product synonym:FAD-dependent oxidoreductase"
                     /note="original gene:dnmZ"
                     /note="category:5.1 general function"
                     /transl_table=11
                     /inferenece="InterPro:IPR013786"
                     /inferenece="InterPro:IPR006092"
                     /inferenece="InterPro:IPR006090"
                     /inferenece="InterPro:IPR009100"
                     /inferenece="InterPro:IPR006091"
                     /inferenece="InterPro:IPR009075"
                     /translation="MTKPSVHEHPGVLADNGLCRPKTPAGRRLLDLLERYLPALEAES
                     RDNDREATLPVHLFDRMRKEGVLGATVPEDLGGLGVHSLHDVALALARIAGRDAGVAL
                     ALHMQFSRGLTLDFEWRHGAPSTRLEEAGAPVRLAAPVVARTTPGLTVLDNWDGMGMR
                     SSGSVDIVFDGCP-DRDRVLPRRRAGRRDDAALAGQTSARTHAGYHSATPRRSRIALT
                     ELRRRGGAPAGVRTTVAEIDARLFALHTAVASALTTADRLADDLSGDLAARGRAMMTP
                     FQYAKLLVNRHSVGVVDDCLMLVGGAGYSNSHPLARLYRDVRAGGFMHPYNFTDGVDY
                     LSEVALGR"
     CDS             13135..13761
                     /locus_tag="Adria_00190"
                     /product="NDP-hexose epimerase"
                     /note="original product:putative epimerase"
                     /note="original gene:dnmU"
                     /note="category:2.3 modification addition of sugar moiety"
                     /EC_number="5.1.3.-"
                     /transl_table=11
                     /inferenece="InterPro:IPR000888"
                     /inferenece="InterPro:IPR014710"
                     /inferenece="InterPro:IPR011051"
                     /translation="MKARELAVQGAYTFEPEVFPDERGLFVSPFREDAFTAAVGHPLF
                     PVRQTNHSRSRRGVVRGVHYTVTPPGSAKYVYCARGRSLDIVVDVRVGSPTYGRWDAV
                     ELEPREFRAVYFPVGVGHAFVALEDDTVMSYMLSGEYVQANELAVSVLDPALGLPVPG
                     DLEPLLSGRDRAAPPLEQARAAGTLPEYAACRAVESELWPPAGSRGDG"
     CDS             13769..14692
                     /locus_tag="Adria_00200"
                     /product="NDP-hexose C-4 ketoreductase"
                     /note="original product:thymidine
                     diphospho-4-keto-2,3,6-trideoxyhexulose reductase"
                     /note="original gene:dnmV"
                     /note="category:2.3 modification addition of sugar moiety"
                     /transl_table=11
                     /inferenece="InterPro:IPR001509"
                     /inferenece="InterPro:IPR016040"
                     /translation="MRVVVLGATGSVGRQVCAAYQAHGWDVHGVARRPAPHLSGCGFT
                     ELDLAAAAPGRIATVLGDLPADVVVNAAGGWGDTEEEMTYSHLRLVRRLVEALALLPF
                     RPRLVHLGSVHEYGPVPAGTLLHEDLLPEPVTPYARVKLETSSAVLTAARAGVLDAVV
                     LRAANMSGPHPPQESFLAALMARISTAFAHGGRLELSVADARRDFIDVRDVAQAVVRA
                     GRAPAVGGLVVNIGRGDAVPIGDLVGWLLEAAAFPEDRVDRREAPVRSKGGDWTRLDI
                     GRARRLLSWAPRIGLRDSVHSMWRTAHGAPA"
     CDS             complement(15986..16804)
                     /locus_tag="Adria_00210"
                     /product="transcriptional activator"
                     /note="original gene:dnrI"
                     /note="category:4.1 transcriptional regulator"
                     /transl_table=11
                     /inferenece="InterPro:IPR001867"
                     /inferenece="InterPro:IPR011990"
                     /inferenece="InterPro:IPR016032"
                     /inferenece="InterPro:IPR011991"
                     /inferenece="InterPro:IPR005158"
                     /translation="MQINMLGPLVAHHNGTSVTPIARKPRQVFSLLALQAGTVVPVPA
                     LMDELWGTQPPASALTTLQTYILQVRRGITVALGASHNGPAKDVLRTCYGGYLLDVDP
                     TNTDVYAFERLAEEGKRACERGELDLASARFRQALDLWRGDALVDVHAGMRIGMEVAR
                     LEESRLGVLEARMETDLRLGRHAGLLPELSALTARHPMHENLWAQFMIALHRSGRTSQ
                     ALEAFIKLRKTLVNELGVEPSARLQHLQHAILRADPGIDRNGPEVPAAASVALA"
     CDS             complement(14851..15963)
                     /locus_tag="Adria_00220"
                     /product="putative NDP-hexose C-3 aminotransferase"
                     /gene="dnmJ"
                     /note="original gene:dnrJ"
                     /note="category:2.3 modification addition of sugar moiety"
                     /EC_number="2.6.1.-"
                     /transl_table=11
                     /inferenece="InterPro:IPR015421"
                     /inferenece="InterPro:IPR015424"
                     /inferenece="InterPro:IPR015422"
                     /inferenece="InterPro:IPR000653"
                     /translation="MSTYVWQYLNEYREERADILDAVETVFESGQLILGTSVRSFEEE
                     FAAYHGLPYCTGVDNGTNALVLGLRALGIGPGDEVVTVSNTAAPTVVAIDAVGATPVF
                     VDVHEENYLMDTGRLRSVIGPRTRCLLPVHLYGQSVDMTPVLELAAEHDLKVLEDCAQ
                     AHGARRHGRLVGTQGHAAAFSFYPTKVLGAYGDGGAVVTPDAEVDRRLRRLRYYGMGE
                     RYYVVDTPGHNSRLDEVQAEILRRKLRRLDAYVEGRRAVARRYEEGLGDLDGLVLPTI
                     AEGNDHVYYVYVVRHPERDRILEALTAYDIHLNISYPWPVHTMSGFAHLGYGPGDLPV
                     TERLAGEIFSLPMYPSLRPDAQEKVIDAVREVVGSL"
     CDS             complement(17088..18335)
                     /locus_tag="Adria_00010"
                     /product="cytochrome P450"
                     /note="original product:daunorubicin C-14 hydroxylase"
                     /note="original gene:doxA"
                     /note="category:3.3 modification reduction"
                     /transl_table=11
                     /inferenece="InterPro:IPR017972"
                     /inferenece="InterPro:IPR001128"
                     /inferenece="InterPro:IPR002397"
                     /translation="MAVDPFACPMMTMQRKPEVHDAFREAGPVVEVNAPAGGPAWVIT
                     DDALAREVLADPRFVKDPDLAPAAWRGVDDGLDIPVPELRPFTLIAVDGEAHRRLRRI
                     HAPAFNPRRLAERTDRIAAIAGRLLTELADASGRSGKPAELIGGFAYHFPLLVICELL
                     GVPVTDPAMAREAVSVLKALGLGGPQSGGGDGTDPAGGVPDTSALESLLLEAVHSARR
                     NDTPTMTRVLYERAQAEFGSVSDDQLVYMITGLIFAGHDTTGSFLGFLLAEVLAGRLA
                     ADADEDAVSRFVEEALRYHPPVPYTLWRFAATEVTIGGVRLPRGAPVLVDIEGTNTDG
                     RHHDAPHAFHPDRPSWRRLTFGDGPHYCIGEQLAQLESRTMIGVLRSRFPEARLAVPY
                     DELRWCRKGAQTARLTELPVWLR"
     CDS             complement(18353..19180)
                     /locus_tag="Adria_00020"
                     /product="doxorubicin biosynthesis protein"
                     /note="original product:doxorubicin biosynthesis enzyme
                     DnrV"
                     /note="original gene:dnrV"
                     /note="category:5.2 function unknown"
                     /transl_table=11
                     /inferenece="InterPro:IPR025870"
                     /inferenece="InterPro:IPR004360"
                     /translation="MTRFAPGAPAWFDLGSPDVAASADFYTGLFGWTATVVSDPGAGG
                     YTTFSSDGKLVAAVARHQIDTPYHRPYGPGNDQHGMPAIWTVYFATDDADALTKRVET
                     AGGEVIMTPMDVLGLGRMAVFADPAGAAFAVWRKGVMEGAEVTGVPGSVGWVELVTDG
                     IGAARDFYPATLGLAPADTGLKGVTDPVWHIGDTPVAGTQELGVTGAVRPHWAVLFAV
                     HDCDATVRRAVELGGSVENEPADTPRGRRADLLDPHGAGFSVVELREGYPAAAGGAS"
     CDS             complement(19284..20147)
                     /locus_tag="Adria_00030"
                     /product="putative oxidoreductase"
                     /note="original product:daunorubicin C-13 ketoreductase"
                     /note="original gene:dnrU"
                     /note="category:5.1 general function"
                     /transl_table=11
                     /inferenece="InterPro:IPR002198"
                     /inferenece="InterPro:IPR002347"
                     /inferenece="InterPro:IPR016040"
                     /translation="MTASTPHHGTPRGGLSGRTVLVTGATSGIGRAAALAVARQGARV
                     VLVGRDPERLRTVTNEVARTAGPAPDAFRADFAELRQVRDLGERLRDRYPRIDVMASN
                     AGGMFWSRTTTQDGFEATIQVNHLAGFLLARLLRERLAGGRLILTSSDAYTQGRIDPD
                     DLNGDRHRYSAGQAYGTSKQANIMTAAEAARRWPDVLAVSYHPGEVRTRIGRGTVASS
                     YFRFNPFLRSAAKGADTLVWLASAPAEELTTGGYYSDRRLSPVSGPTADAGLAAKLWE
                     AGAAAVGDTAH"
     CDS             complement(20144..20398)
                     /locus_tag="Adria_00040"
                     /product="polyketide synthase acyl carrier protein
                     subunit"
                     /note="original product:daunorubicin acyl carrier protein"
                     /note="original gene:dpsG"
                     /note="category:1.1 PKS"
                     /transl_table=11
                     /inferenece="InterPro:IPR009081"
                     /inferenece="InterPro:IPR006162"
                     /translation="MAELSLAELREIMRQSLGEDEVPDLADADTVTFEDLGLDSLAVL
                     ETVNHIERTYGVKLPEEELAEVRTPHSMLIFVNERLRAAA"
     CDS             20498..21082
                     /locus_tag="Adria_00050"
                     /product="hypothetical protein"
                     /note="original product:daunorubicin biosynthesis enzyme"
                     /gene="dnmW"
                     /note="original gene:dpsH"
                     /note="category:5.4 hypothetical protein"
                     /transl_table=11
     CDS             21134..22651
                     /locus_tag="Adria_00060"
                     /product="putative NDP-hexose 2,3-dehydratase"
                     /note="original product:doxorubicin biosynthesis protein
                     DnmT"
                     /note="original gene:dnmT"
                     /note="category:2.3 modification addition of sugar moiety"
                     /transl_table=11
                     /inferenece="InterPro:IPR005212"
                     /translation="MTAQIARSVLARDGLGSGMDRFWAWYADRSAQVVHRTERIPLDD
                     LKGWSRHPVTGTVSHHTGRFFSIEGLDVHIPGAPVPRWSQPIVNQPEVGILGFLVKER
                     HGVLHCLVQAKFEPGNPGGLQLSPTVQATRSNYTRVHGGKAIPYLEHFRDTAERQVVA
                     DVLQSEQGSWFYRKRNRNMIVQVIDEVPLHEDFHWLTLGQLHRLLGVENLVNMDARTV
                     LACLPFASEGAHPLADAEPAGADGPGGGHPVVPARPDGGEGRVDTGFHRSLVRSCAAA
                     EGSLHSTVDIVSWIADLRSRTDVVTRPAALNALPHWYERDGAIAHESGRFLEVMAVDV
                     TAASREVPGWSQPMIEPKDQGVAAFLVRRIDGVLHVLAHARVEPGYVDVVEIAPTVQC
                     TPGSLHALPAEARPRFLDAVLEAPPERVRYATVLAEEGGRFYHAVNTYMIVEADHDIP
                     DGGEYRWLTLHQLVGLLRHSHYVNVQARTLVACLHSLSVGSPVTRSAVPSAPPRR"
     CDS             22659..23990
                     /locus_tag="Adria_00070"
                     /product="putative glycosyltransferase"
                     /note="original product:putative baumycin biosynthesis
                     protein"
                     /note="original gene:dnrH"
                     /note="category:5.1 general function"
                     /transl_table=11
                     /inferenece="InterPro:IPR004276"
                     /inferenece="InterPro:IPR010610"
                     /translation="MRVLFATMAARSHVYAQVTLASALRTAGHEVLVASQPDVLDDIV
                     RAGLTAVRIGEDLNIEEETREANASFEDDRNLGGLAMSNSRDDPFPWDHALGMFTAMT
                     AMVFQNVCPEPMVDDLVGLARDWRPDLVVWDPLTLAGPVAARLSGAAHARLLFGPDQM
                     GRNRTAFRALLDRQPPELRDDPLAEWLTWTLERCGGSAGDMSEELVLGQWTIDPTPPS
                     MRIPLDLPCVPVRYVPYNGPSLLPGWLREPPRHPRRLCLTLGVSLGEATGAGTVAASD
                     VLAAVDGLDVEVVATLPRELREELGTLPANVRAVDFVPLNALLPSCSGIIHHGGSGTF
                     MTALVHAIPQLIVPDMMWDAMEKAHGLARSGAGSYVDARDVSPELLRERVLALLDDPS
                     YAAGARRVRAEIVGTPSPNDIVPVLERLTAEHRAGGAEGGPALKSPSTGGA"
     CDS             24018..24773
                     /locus_tag="Adria_00230"
                     /product="putative aklaviketone C-7 ketoreductase"
                     /note="original product:daunorubicin-doxorubicin
                     polyketide synthase"
                     /gene="dnrE"
                     /note="original gene:dnrH"
                     /note="category:3.3 modification reduction"
                     /transl_table=11
                     /inferenece="InterPro:IPR016040"
                     /inferenece="InterPro:IPR002347"
                     /inferenece="InterPro:IPR002198"
                     /translation="MENTQRSVIVTGGGSGIGRAVARAFAARGDRVLVVGRTAGPLAE
                     TVDGHKDAHTLAVDITDPAAPEAVVREVRERLGGVVDVLVNNAATAAFGHLGELHRTA
                     VEAQVATNLVAPVLLTQALLGPLETASGLVVNIGSAGALGRRAWPGNAVYGAAKAGLD
                     LLTRSWAVELGPRGIRVVGVAPGVIGTGAGVRAGMSQEAYDGFLEAMGQRVPLGRVGR
                     PEDVAWWVVRLADPEAAYASGAVLAVDGGLSVT"
     CDS             complement(24908..25855)
                     /locus_tag="Adria_00240"
                     /product="cyclase/dehydratase"
                     /note="original product:daunorubicin-doxorubicin
                     polyketide synthase"
                     /note="original gene:dpsF"
                     /note="category:3.4 other modification"
                     /transl_table=11
                     /inferenece="InterPro:IPR019587"
                     /inferenece="InterPro:IPR023393"
                     /translation="MSELPLQQTEHEIHTSAAPDAVFAVLADARAWPAVFPPSVHVEQ
                     VEHTGSSERIRIWATANGSLRTWTSRRELDERARRIRFRQEVSAHPVAAMGGEWIVEE
                     AGDGGTRVRLTHDFRAVDDDPETIGWIHRAVDRNSEAELASLRTALERPDGTAPTTFE
                     DTVVVRGRAEDVYDFLHRSDLWKKRLSHVARIAVKEEEPGLQHMEMDTLTADGSVHTT
                     ASVRVCFPERRVIVYKQLRTPPLLALHLGRWSVRPADDGDGIAVTSAHTVSVARSAIP
                     GVLGAGASETDAVDFVRRALGRNSLLTLEAARQYAESSA"
     CDS             complement(25885..26670)
                     /locus_tag="Adria_00250"
                     /product="polyketide C-9 ketoreductase"
                     /note="original product:daunorubicin-doxorubicin
                     polyketide synthase"
                     /note="original gene:dpsE"
                     /note="category:3.3 modification reduction"
                     /transl_table=11
                     /inferenece="InterPro:IPR002198"
                     /inferenece="InterPro:IPR002347"
                     /inferenece="InterPro:IPR020904"
                     /inferenece="InterPro:IPR016040"
                     /translation="MSEAADRVALVTGGTSGIGLAVVRKLAQDGTRVFLCARDESAIT
                     GTVKELQASGLEVDGAPCDVRSTADVDRLVQTARNRFGPIDIVVNNAGRGGGGVTAEI
                     TDDLWLDVVDTNLSGAFRVTRAVLTGGAMQEHGWGRIISIASTGGKQGVALGAPYSAS
                     KSGLIGFTKAVALELAKTGITVNAVCPGYVETPMAQGVRQRYAAFWGITEDDVLEKFQ
                     AKIPLGRYSMPEEVAGMVHYLASDSADSITAQAINVCGGLGSY"
     CDS             26862..27251
                     /locus_tag="Adria_00260"
                     /product="putative C-12 oxygenase"
                     /note="original product:anthraquinol monooxygenase"
                     /gene="dnrG"
                     /note="category:3.3 modification reduction"
                     /transl_table=11
                     /inferenece="InterPro:IPR011008"
                     /inferenece="InterPro:IPR007138"
                     /translation="MPQPEPNDAGSGSVTFVNRFTLSGSAEDFEAAFAETAEFLCRRP
                     GFRWHALLVPADTGPGSADARPQYVNIAVWDDEASFRAAVAHPEFPAHAAALRALSTS
                     EPTLYRHRQIRVAPDVPAVSGPGGRTT"
     CDS             27248..28507
                     /locus_tag="Adria_00270"
                     /product="polyketide synthase beta-ketoacyl synthase
                     subunit"
                     /note="original product:daunorubicin-doxorubicin
                     polyketide synthase"
                     /note="original gene:dpsA"
                     /note="category:1.1 PKS"
                     /transl_table=11
                     /inferenece="InterPro:IPR016038"
                     /inferenece="InterPro:IPR014030"
                     /inferenece="InterPro:IPR014031"
                     /inferenece="InterPro:IPR018201"
                     /inferenece="InterPro:IPR016039"
                     /translation="MNRRIVITGIGVVAPGAVGTKPFWELLLSGTTATRAISTFDATP
                     FRSRIAAECDFDPVAAGLSAEQARRLDRAGQFALVAGQEALADSGLRIDEDSAHRVGV
                     CVGTAVGCTQKLESEYVALSAGGAHWVVDPGRGSPELYDYFVPSSLAAEVAWLAGAEG
                     PVNIVSAGCTSGIDSIGYACELIREGTVDAMVAGGVDAPIAPITVACFDAIRATSDHN
                     DTPETASRPFSRSRNGFVLGEGGAIVVLEEAEAAVRRGARIYAEIGGYASRGNAYHMT
                     GLRADGAEMAAAITAALDEARRDPSDVDYVNAHGTATKQNDRHETSAFKRSLGEHAYR
                     VPISSIKSMIGHSLGAVGSLEVAATALAVEYGVIPPTANLHDPDPELDLDYVPLTARE
                     KRVRHALTVGSGFGGFQSAMLLSRLER"
     CDS             28513..29790
                     /locus_tag="Adria_00280"
                     /product="polyketide synthase chain length factor subunit"
                     /note="original product:daunorubicin-doxorubicin
                     polyketide synthase"
                     /note="original gene:dpsB"
                     /note="category:1.1 PKS"
                     /transl_table=11
                     /inferenece="InterPro:IPR016038"
                     /inferenece="InterPro:IPR014030"
                     /inferenece="InterPro:IPR014031"
                     /inferenece="InterPro:IPR016039"
                     /translation="MTGTAARTASSQLHASPAGRRGLRGRAVVTGLGIVAPNGLGVGA
                     YWDAVLNGRNGIGPLRRFTGDGRLGRLAGEVSDFVPEDHLPKRLLAQTDPMTQYALAA
                     AEWALRESGCSPSSPLEAGVITASASGGFAFGQRELQNLWSKGPAHVSAYMSFAWFYA
                     VNTGQIAIRHDLRGPVGVVVAEQAGGLDALAHARRKVRGGAELIVSGAVDSSLCPYGM
                     AAQVKSGRLSGSDNPTAGYLPFDRRAAGHVPGEGGAILTVEDAERAAERGAKVYGSIA
                     GYGASFDPPPGSGRPSALARAVETALADAGLDGSDIAVVFADGAAVPELDAAEAEALA
                     SVFGPRRVPVTVPKTLTGRLYSGAGPLDVATALLALRDEVVPATAHVDPDPDLPLDVV
                     TGRPRSLADARAALLVARGYGGFNSALVVRGAA"
     CDS             29787..30848
                     /locus_tag="Adria_00290"
                     /product="polyketide synthase beta-ketoacyl synthase
                     subunit"
                     /note="original product:daunorubicin-doxorubicin
                     polyketide synthase"
                     /note="original gene:dpsC"
                     /note="category:1.1 PKS"
                     /transl_table=11
                     /inferenece="InterPro:IPR016039"
                     /inferenece="InterPro:IPR013747"
                     /inferenece="InterPro:IPR016038"
                     /inferenece="InterPro:IPR013751"
                     /translation="MSVPQGAPGDLYVAGCGVWLPPPVTTEQALAAGHCDRRLASSTR
                     MLSVAVADKETPAEMAALAAQTALDRSGVAPAHVDLVLHASLYFQGHHLWAPSSYVQR
                     VAVGNRCPAMEVRQVSNGGMAALELARAYLLAAPDRVAALITTGDRMHPPGFDRWSSD
                     PGTVYADGGTALVLSRQGGFARLRSLVTVSEPVLEGMHRGGHPFGPPSPEEQRAVDLD
                     AHKRAYVAEAGSSFSVARVSAGQEEALTGALEAAGAGLDDISRVVLPHMGWRRLSAAY
                     FNKWHIQPERTTWEFGRRTGHLGGGDPIAGFDHLVGSGRLAPGELCLLVSVGAGFSWS
                     CAVVELLERPSWAAAPAAR"
     CDS             30859..31872
                     /locus_tag="Adria_00300"
                     /product="putative acyl-ACP thioesterase"
                     /note="original product:daunorubicin-doxorubicin
                     polyketide synthase"
                     /note="original gene:dpsD"
                     /note="category:1.4 Other"
                     /transl_table=11
                     /inferenece="InterPro:IPR016035"
                     /inferenece="InterPro:IPR014043"
                     /inferenece="InterPro:IPR016036"
                     /inferenece="InterPro:IPR001227"
                     /translation="MDAPAILLMFPGQGSQHARMAVGLYGSEPAFTAAMDEVFDAYDD
                     AGDSEGGRLRADWLSDHPAVPLDHVTRSQPLLFAVDYALGRMVMATTGRPWALLGHSV
                     GEMAAAALAGVFTLRDAAGLLLDRVRRLAQAPPGGMLAVAAAEDVLGPYLGNGEVVVA
                     AVNSPRQTILAGPVASLAGVARALREAGLTCREVPSLTAFHSPMLAPIAAGAAERFAS
                     TRVAPSIPLRSGYRPGAVTGQLAADPSYWAGHPLETVRFWPALDAMLGSRTGVVCLET
                     GPGQGLSTIARRHPTVRFGKNSVVPLLPPQAGTAEVDRTSVAAALAAVREQGTVLSGR
                     PGR"
     CDS             complement(31850..32710)
                     /locus_tag="Adria_00310"
                     /product="aklanonic acid O-methyltransferase"
                     /gene="dnrC"
                     /note="category:3.2 modification methylation"
                     /EC_number="2.1.1.-"
                     /transl_table=11
     CDS             32894..33331
                     /locus_tag="Adria_00320"
                     /product="aklanonic acid methyl ester cyclase"
                     /note="original product:methylaklanonic acid cyclase"
                     /note="original gene:dnrD"
                     /note="category:3.4 other modification"
                     /transl_table=11
                     /inferenece="InterPro:IPR009959"
                     /translation="MSTQIDLVRRMVEAYNTGKTDDVAEFIHLEYLNPGALEHNPELR
                     GPEAFAAAVTWLKYAFSEEAHLEEIEYEENGPWVRAKLALYGRHVGNLVGMPATGRRF
                     SGEQIHLIRIVDGKIRDHRDWPDYLGTYRQLGEPWPTPEGWRP"
     CDS             33377..34447
                     /locus_tag="Adria_00330"
                     /product="C-4 O-methyltransferase"
                     /note="original product:carminomycin o-methyltransferase"
                     /note="original gene:dnrK"
                     /note="category:3.2 modification methylation"
                     /EC_number="2.1.1.-"
                     /transl_table=11
                     /inferenece="InterPro:IPR011991"
                     /inferenece="InterPro:IPR016461"
                     /inferenece="InterPro:IPR001077"
                     /translation="MTAEPTVAARPQQIDALRTLIRLGSLHTPMVVRTAATLRLVDHI
                     LAGARTVKALAARTDTRPEALLRLIRHLVAIGLLEEDAPGEFVPTEVGELLADDHPAA
                     QRAWHDLTQAVARADISFTRLPDAIRTGRPTYESIYGKPFYEDLAGRPDLRASFDSLL
                     ACDQDVAFDAPAAAYDWTNVRHVLDVGGGKGGFAAAIARRAPHVSATVLEMAGTVDTA
                     RSYLKDEGLSDRVDVVEGDFFEPLPRKADAIILSFVLLNWPDHDAVRILTRCAEALEP
                     GGRILIHERDDLHENSFNEQFTELDLRMLVFLGGALRTREKWDGLAASAGLVVEEVRQ
                     LPSPTIPYDLSLLVLAPAATGA"
     CDS             34478..35374
                     /locus_tag="Adria_00340"
                     /product="putative rhodomycin D esterase"
                     /note="original
                     product:10-carbomethoxy-13-deoxycarminomycin esterase"
                     /note="original gene:dnrP"
                     /note="category:3.4 other modification"
                     /transl_table=11
     CDS             35417..36733
                     /locus_tag="Adria_00350"
                     /product="putative glycosyltransferase helper protein"
                     /note="original gene:dnrQ"
                     /note="category:2.3 modification addition of sugar moiety"
                     /transl_table=11
                     /inferenece="InterPro:IPR002397"
                     /inferenece="InterPro:IPR001128"
                     /translation="MPTPTSAPPAAPTDSELGRHLLTVRGFHFVFGALGDPYARRLRG
                     EADHLSLGELVRDRGPLHGSALGTWVTADGGISARLLDDPLLGPRHPASEGPQEHVLE
                     NVWETWRTCHVTPLGEDLLTPAAADSDRLAALLGPVLGPRTCTAWQVDAGRAVHRVLD
                     GLPPHFDVVSDLARPAIAGSLAAVLGLPDEARAELPDLLAACGPVLDSALCPPRLPVA
                     RAMTQALRRVRELMAAAVANHLTAPADGAVSALLAVDPGGGRDPGDTVTAAVLSTVVG
                     AETAITTVANAVMALLKHDEQWSLLRADPGRAADAVEETLRWAPPVTLRSLITQGEVQ
                     IGGETLEADQHVVVLVDAAQRDPALYEDPDRFRLDRPRSPGFTHMALAGRDHLGLVAP
                     LVRVQCTAVLRALAERLPGLRAEGEPLRRGRSPVVRAPLSLRLAQK"
     CDS             36752..38047
                     /locus_tag="Adria_00360"
                     /product="putative glycosyltransferase"
                     /note="original product:glycosyl transferase"
                     /note="original gene:dnrS"
                     /note="category:2.3 modification addition of sugar moiety"
                     /transl_table=11
                     /inferenece="InterPro:IPR010610"
                     /inferenece="InterPro:IPR004276"
                     /translation="MKVLVTAFAMDAHFNGVVPLAWALRAAGHDVRVASQPALTDSIT
                     RAGLTAVPVGTDHQVQAAMGAMAPGVFALHLNPDYLENRPELLDLEFLEASTSMLTAA
                     FYAQINNDSMIDEMVDFAAWWRPDLVVWEPFTFGGAVAAQVTGAAQARLLWGPDLFLR
                     VHDRFQQVLHEVPAERRDDALEEWLTWTLERHGAAFGPEVISGHWTIDQMPPSVRFAT
                     ARPTVPMRFVPYNGPVPAVVPPWLRADPGRPRVLLTQGITERSTGFTGLPRAGELLAS
                     IAELDAEVVATVKAEEREGLPPLPGNVRVVDSLSLHVVLPSCAAVVHHGGAGTWATAA
                     LHGVPQLALAWQWDDVFRAGQLEKLGAGIFLPPHGEGASAGRVRDRLAQVLAEPSFRQ
                     GAARIRAEMLRTPAPGAVVPTLEQLTARHRAPAGQGVRH"
     CDS             complement(38919..41213)
                     /locus_tag="Adria_00370"
                     /product="UvrA-like protein"
                     /note="original product:daunorubicin resistance protein"
                     /note="original gene:drrC"
                     /note="category:4.4 resistance"
                     /transl_table=11
                     /inferenece="InterPro:IPR017871"
                     /inferenece="InterPro:IPR003439"
                     /inferenece="InterPro:IPR003593"
                     /translation="MQQQAIQIIGARENNLKGISVEVPKHKVTVFTGVSGSGKSSLVF
                     DTIAAESQRQLNETFTAFVRNRLPKYGQPDVDDIANLSAAVIIDQKRIGGNARSTVGT
                     ITDIYALLRLLYSRVGKPWIGYSNAFSFNDPSGMCPDCEGLGHRVQVDLDKLLDRSKS
                     LNEGAIRHPAFNVGGWFWKLYANSGLFDNDKKLRDYTESEWQAFLYGAQGSIALEWQG
                     GKVNSKYEGLMDKFNRLYLRKEPDEMSAKNRVALQQVVTRGPCDTCKGQRLSQRALGC
                     RINGRNIAELASLEIADLMEAVKKVDTSSVSTLTASLIERLQHLIELGLGYLSLNRET
                     STLSGGESQRIKMVRHLNSSLVDMVYIFDEPTIGLHPSDVQRLSRLLMELAEKGNTVL
                     VVEHDRDIIEVAEHVIDIGPGAGRHGGEIVYQGDVRGLTEADTPTGRFLRRIIPIKER
                     FRGPRGHLEVTGARIHNLKDISVRIPLGVLTAVTGPAGSGKSTLIHDVLLRQHPSAVV
                     IDQSAVTTNRRSNPATYTGIMDEIRRLFARENQVSPSLFSFNSEGACPTCQGHGIIYT
                     DLAFMDPMITTCEVCAGMRFTDDVLRLTLRGQNIHDVLSMSAAEAAEFFTEPKVAKTL
                     RSINQVGLGYLQLGQPLNTLSGGECQRIKLATELGKKGSVYVMDEPTTGLHMSDVDSL
                     VHLVDGLVEKGDSVIVIEHNLDVVKHADWVVDLGPGGGSEGGRVIFEGTPADLAEAEH
                     SVTGRFLAASLAGAGSEADHRARR"
ORIGIN      
        1 ggatccatca ggtcggtcag cgggcgtgac gccctctccg cccagcgcag ggcaagccgc
       61 acatccggag gcgccgtccg cgactccggc cggggaacga cgaacgccca gtttcgaagc
      121 gcctgccgca gcagctcgtc actcgggcgg cctcgcacgt cccggagcat cgccagcgtg
      181 atcgcgcaca gcgcgtcatt ggtctcgttg cgtgtcttcg ccgcgatctg cggccaacgc
      241 atctccagat actcgagagg caacactctg ctcctggaca gcgagagcca gccaaggtca
      301 ctcttcataa ccgtatggtc accaaatggc tcgctctcgc atcgccaatc tacgagtggt
      361 gagtcgtcgc ctctgcggcc ccctggaagt ggctcaccct cgcattaacc ggccgacgac
      421 cctaccgcgg cacatcgact ccccaccgta ctacgcatac gacctcgctg acgaggctgg
      481 cctgttcctc atgtacggac gggtggtctg ccaggcccag tccccaactg cctacaggtg
      541 cacctgaaca ccaatctgtt gcgccagcag gcgcacgtta tcccgggccc cgggaccgcg
      601 cccgcgatcc gtacaccagt tgggcttgag cggcgccgcc taggctccgg cggcatgaag
      661 gctctcgtcc tgtccggggg gtcgggcacg cgcctgcggc ccttcacaca cacgtctccc
      721 aagcagttgg tgccggtagc caacaagccg gtcctctact acgtcctcga ggacatcgct
      781 caggccagca tcaccgaggt cggcatcgtc gttggggaga cgtccaacga gatccgcaag
      841 gccgtcggga gcggcgacag attcgggctc cgcgtcacct accttccgca ggaggcgccc
      901 ctgggtctgg ctcacgctgt cctcatcgcc cgcgactatc tcggcgagga ggacttcgtc
      961 atgtatctcg gggacaactt cgtggtcggc ggcatcgcag ggaactcgtc gacgttccgc
     1021 gcggagcgcc ccgatgccca gatcctgctc acccgtgtct ccgacccgtc cagcttcggc
     1081 gtggccgaga tcggctgtga cggccgggtc gtcgcgctgg aggagaagcc gaggcacccc
     1141 cgcagtgatc tcgccgtggt cgggatctac ttgttcacgc cggtcgtgca cgaggcggtg
     1201 cgcgccctca caccgtcacg gcggggcgag ctggaaatca cggacgccct ccagtggctc
     1261 ctcgacggac cctacgacgt gcggtacacc accatctccg gttattggaa ggacacggga
     1321 aacgtcgccg acatgctgga ggtgaaccgt gccgtgctgg acgggatcga gccgggcatg
     1381 gagggccagg ccgacgcggc gagcgaactg gtggggcggg tgcggatcga ggcgggcgcg
     1441 cagatccggg cgtcgcgcat cgtggcccgc cgtcatcggg ccggacgtgt gacggatcgt
     1501 acgtcggccc tacacgtcga tcgcggagac tgctcgatcg agacagcgag atcgagtctc
     1561 catcatgctg ggcgactccc ggctcacggc acgcgccggg tccagcactc gctcctgggg
     1621 cggaacgtga ccgtcgctcc ggccccccgg gtacccgcag gttcccgtct catcctcggt
     1681 gacgacagca gggtggagat ctcctcatga ccatgaagat cctggtgaca ggcggtgccg
     1741 gcttcatcgg ctcgcactac gtccgcgccc tgctcggccc gcgcggcgac ggctcggtcg
     1801 gggtcactgc tggacagcct gacctatgca ggcaatccgg ccaacctcga tcccgtccgc
     1861 ggcgacgagc ggttcgcctt cgtccacggt gacatctgcg atgccccgct cgtcgatcga
     1921 ctggtcgccg agcacgacca gatcgtccac ttcgcagccg agtcacacgt cgaccgctcg
     1981 gtgcgctcgg ggccgcggag ttcgtgcgca cccaacgtga tgggtacgca aacgctgctg
     2041 gacgcggccc tgcgccacgc ccccaggatt ttcgtccaca tctccacgga cgaggtgtac
     2101 ggctccgtcg atgtcggtgc cagcacagag accgatccgc tgcaccccag ttcggcgtac
     2161 gcgggcacga aggcgtcaag cgatctgttg gcgctgtcgt accaccgcac gcacgggctg
     2221 gacgtccgga tcacccggtg ctcgaacaac tacggcaccc atcagcatcc ggagaaggtc
     2281 attccgcgtt ttgtgacgac cctgctgagc ggtggccggg tgccgctcta cggtgacggc
     2341 gggaacctgc ggaactggct gcacgtcgag gaccacgtcg acgcggtgga actggtaagg
     2401 gagggaggct ccccgggcga gatctacaac atcggcggcg gcacggagct gtccaacaag
     2461 gagctgacgg ctctcctgct ggacgcggtg ggcgccggct gggactccgt ggaactcgtc
     2521 gccgaccgca agggacacga ccggcgctac gccgtcgacc acgggaagat caccgcgctg
     2581 ctcgggtacc ggccacgccg ggacttccgg gactcgctcg ccgagacagt ggcctggtac
     2641 cgcgaccgcc gctcctggtg ggcaccgctc accggatcct gaNNggatcc tgagccgacg
     2701 ggccctccgc cgccagtgac cgagggtcag atccagccgg acatactggc gatgcgtacc
     2761 gcgtcgagcc ggttgcgcgc gtccatcttc cggacggtcg tcgccagata gttgcggacc
     2821 gtcccgggag agagcgacag cttgacggca atttcgttga tgtcgtcccc cgcggcggcg
     2881 agctggagta tctccatctc ccgctccgtg agcgggcatc cggtgttgcc ccaggcggcg
     2941 agcgtcagtt cggtgtcgaa gacgcggcgg ccctcgtgca cgctgcgtat ggcatcgctg
     3001 aggtgcgccg gaggggagct cttcagcacc aggccgccga ggccggatgc cagcgactgg
     3061 cgcactgtag ccagccgggc gaatcgcgcg gtgagcagtg tgcggcagtc cgggaggtgc
     3121 tcctgaatcg ccatggcgga gagaagaccc tcccgctcgt gcatgtcgac atcgatgacc
     3181 gtcacgtcgg ggctgtactc cagaaccgtc cggatcaact cgctgccgac gcctgtggaa
     3241 gcgacgactt tgatgtccga ttcacgctcc actaggagaa ccagcgcggc acggaccatt
     3301 tccagctctt cagcaatcac gactcggatg gtcatgcatt cccttccccc gtcgatggaa
     3361 ctccgcccct tcgcgatgct atttcggcca acatggccgt atcgcgatta gcggattccg
     3421 tgcagcaata gggtcggggt ggcgcagcga tcagtcctcg ctggaccggc cccccctccc
     3481 ggtaccctcc cggtaccctc ccggtctgca ctttcccttc gggaaagccc aggcggactc
     3541 tcccgggagt gaacgggcag gcgagtttga ccctgaggcc cgcgaccggg tgctactcat
     3601 cgactccccc gtcttctcgg caaggaactg gcgtggtctc cgcaaaccga gcttgcgtac
     3661 gactataaga ggtgattcag gtagtggcta tgggtgcctg tgtggctggg gaaaagacgg
     3721 cgggaatcgc ggccatagag tgaccgcgat tcgtgccacc ctggaagcat gaccgagacg
     3781 ccatcccgca tgctccgtct gctgtccctc ctccagaaca gccgggactg gccagggcgc
     3841 aagctggcgg agcggctcgg ggtcagcccg cggacgctgc gccgagacgt ggaacggttg
     3901 cgggatctcg gctacccggt tcaggccata ccgggcgtcg gcggaggcta ccggctggag
     3961 gcgggcgcca gtctgccgcc gctgctcctc gacgacgacg aggcggtcgc catcgcggtc
     4021 ggattacgga cggccgcagg gggaagcgtg gcggacatcg aggacacctc gatccgcgcg
     4081 ctggccaagc tggagcaggt gctgcccaag cggctgcgca gccgggtcaa cgcccttcag
     4141 atgtacaccg tccccatgtt cacggtgacc ccgaccgtga gccccgaaca cctcgcgtca
     4201 gtggcacagg cgtgccgcga ccagcagcgg ctgagattca cctaccgcaa gcgcgacggg
     4261 gagacgagca gccgtctggt ggagccgtac cgtctggtcc atgtgaaccg taagtggtac
     4321 gtgctgtcct gggacatggg acggcaggac tggcgcacct tccgcgtgga ccgcatggaa
     4381 tcgctgctgt tgacgggggt gcgtttccag cagcgcgagt tgcctgccga ggacgcggcg
     4441 gcctatgtgg cgcagtcgat cacgtcctcg ctggccggct accgggcgct ggtcaccctg
     4501 cacgcgccgg tcgaggtggt ggcggagcgg atccgcccgc gcgacggaat cctcacagcg
     4561 gtcgaccacc ggacatgccg gctgcgttcg gccgccgact cgctggagtg gctggcgctc
     4621 accatcggga tgttcggcgt cgagttcgag gtgcacgagc cgcctgaact gattcattac
     4681 atacaggagt tgtcggagcg gctggcccga gccgcgtcgc cgggcgcgga ccgctccgtg
     4741 gtggcgccgc cgacgcggga cgctccggtc agcgggccag cagccgggtg agcagggtgc
     4801 tcagctggtc ctgggcctcc gctcccggcg ctactgccgt acgccaggcg accacgccgt
     4861 ccgggcgcac caagctggcc cccgcccggc cgNNggatcc cgtagacgag accggccggg
     4921 acgttgaggt ccaggccgtc caccgccctc gtcccgttgt agaccttgac gagaccggac
     4981 gtttcgatgg cccgtgtcgg ctgcgtgttc acctaacgcc cccagtagtc acatggagcg
     5041 gacaaagcgt gcactgtaag ttatttcggt caatcgggtt cacgttgagt accgtagccc
     5101 ccaatgagga cacttcatgg ccgcgatggc ttcgttcgcc gagccatttt tcgtacgggg
     5161 ctccaccgcg cctcgtgacc ctttcgagtg gggcgcccga cgctgggggt gcggcaacag
     5221 acgccgcgaa ctcaggaggt ttgaggtggc cttgacgaag ccggatgtcg atgtcctcgt
     5281 ggtgggcggc ggtctcgggg ggctgtccac cgccctgttc ctcgcccgcc ggggggcgcg
     5341 ggtcctgctg gtggagcggc atgccagcac ctcggtcctg cccaaggcgg caggccagaa
     5401 cccgcgcacc atggaactgt tccgcttcgg cggcgtggcc gacgagatcc tggccacgga
     5461 cgacatccgc ggcgcccagg gcgacttcac catcaaggtc gtggagcgcg tgggcggtcg
     5521 cgtcctgcac agcttcgcgg agagcttcga ggaactggtc ggtgcgacgg aacagtgcac
     5581 gcccatgccc tgggcgctcg ctccccagga ccgggtggag cccgtcctgg tggcccacgc
     5641 cgccaagcac ggcgcggaga tccggttcgc caccgaactg acctccttcc aggcgggcga
     5701 cgacggtgtc acggcccgcc tgcgcgacct gggcacggga gcggagagca ccgtgagcgc
     5761 ccgctacctg gtcgccgccg acggaccccg cagcgcgatc cgggagagcc tgggcatcac
     5821 ccggcacggt cacggcaccc tggcccactt catgggcgtc atcttcgagg ccgacctcac
     5881 cgccgtcgta ccgcccgggt ccaccggctg gtactacctg cagcacccgg acttcaccgg
     5941 cacgttcggc cccaccgacc ggcccaaccg gcacaccttc tacgtcgcta cgacccctga
     6001 acgcggcgag aggccggagg actacacacc gcagcgctgc accgagctga tccggctggc
     6061 tgtcgacgcg cccgggctcg tcccggacat cctcgacatc caggcctggg acatggcggc
     6121 gtacatcgcc gaccggtggc gcgaagggcc ggtgctgctg gtcggcgatg ccgccaaggt
     6181 caccccgccc accgggggca tgggcggcaa caccgccatc ggcgacgggt tcgacgtggc
     6241 ctggaagctg gccgccgtgc tgcgcggcga ggcgggcgag cggctcctcg acagctacgg
     6301 ggcggagcgg tcgctcgtgt cccgcctcgt cgtcgacgag tcactcgcca tctacgccca
     6361 gcgcatggct ccccacctgc tcggcagcgt tcccgaggaa cgcggtacgg cgcaggtcgt
     6421 cctgggcttc cgctaccgct ccaccgccgt cgccgccgag gacgacgacc ccgagccgac
     6481 cgaggatccg cgacgcccgt ccgggcgccc cggcttccgc gcaccccacg tctggatcga
     6541 acaggacggc acacggcgtt ccaccgtcga gttgttcggc gactgctggg tgctcctggc
     6601 cgcaccggag ggcggcgcct ggcccgggcg gccgcccgcg ccgccgcgga tctgggcgtc
     6661 cgcctcgacg tccatctcgt cggccgcgat gtcgccgccc cctccggcga actgacgcgg
     6721 acctacggga tcggccgggc gggggccagc ttggtgcgcc cggacggcgt ggtcgcctgg
     6781 cgtacggcag tagcgccggg agcggaggcc caggaccagc tgagcaccct gctcacccgg
     6841 ctgctggccc gctgaccgga gcgtcccgcg tcggcggcgc caccacggag cggtccgcgc
     6901 ccggcgacgc ggctcgggcc agccgctccg acaactcctg tatgtaatga atcagttcag
     6961 gcggctcgtg cacctcgaac tcgacgccga acatcccgat ggtgagcgcc agccactcca
     7021 gcgagtcggc ggccgaacgc agccggcatg tccggtggtc gaccgctgtg aggattccgt
     7081 cgcgcgggcg gatccNNccc ctgggcgccg cggatgtcgt ccgtggccag gatctcgtcg
     7141 gccacgccgc cgaagcggaa cagttccatg gtgcgcgggt tctggcctgc cgccttgggc
     7201 aggaccgagg tgctggcatg ccgctccacc agcaggaccc gcgccccccg gcgggcgagg
     7261 aacagggcgg tggacagccc cccgagaccg ccgcccacca cgaggacatc gacatccggc
     7321 ttcgtcaagg ccacctcaaa cctcctgagt tcgcggcgtc tgttgccgca cccccagcgt
     7381 cgggcgcccc actcgaaagg gtcacgaggc gcggtggagc cccgtacgaa aaatggctcg
     7441 gcgaacgaag ccatcgcggc catgaagtgt cctcattggg ggctacggta ctcaacgtga
     7501 acccgattga ccgaaataac ttacagtgca cgctttgtcc gctccatgtg actactgggg
     7561 gcgttaggtg aacacgcagc cgacacgggc catcgaaacg tccggtctcg tcaaggtcta
     7621 caacgggacg agggcggtgg acggcctgga cctcaacgtc ccggccggtc tcgtctacgg
     7681 gatcctgggg ccgaacggcg ccggcaagtc caccaccatc cgcatgctgg cgacgctgct
     7741 gcgtcccgac ggcggtacgg cccgggtctt cggtcacgac gtgacgagcg aacccgatac
     7801 ggtccgccgc aggatcagtg tcaccggcca gtacgcctcc gtcgacgagg gcctgaccgg
     7861 tacggagaac ctcgtcatga tgggccggct ccagggctac tcctgggccc gggccaggga
     7921 gcgcgccgcc gaactgatcg acggcttcgg actgggcgac gcccgcgacc ggctcctgaa
     7981 gacctactcc ggtggcatgc ggcggcggct cgacatcgcc gcgagcatcg tcgtcacccc
     8041 cgacctgctg ttcctggacg aaccgaccac cggtctcgac ccgcgcagcc ggaaccaggt
     8101 ctgggacatc gtgcgggctc tggtggacgc cggcacgacg gtgctgctga cgacgcagta
     8161 cctcgacgag gcggaccaac tggccgaccg catcgcggtc atcgaccacg gccgggtgat
     8221 cgcggagggc accaccgggg agctgaagtc ctcgctcggg tccaacgtcc tgcggctgcg
     8281 cctccacgac gcccagtcgc gtgccgaggc ggaacggctg ctgagcgcgg aactgggcgt
     8341 cacgatccac cgcgactccg atccgacggc gctgagcgcg cggatcgacg acccccggca
     8401 gggcatgcgg gccctggccg agctgtcgcg cacgcacttg gaggtacgca gtttctccct
     8461 cggccagtcc agtctcgacg aggtcttcct ggcgctgacc ggccacccgg ccgatgaccg
     8521 gtccacggaa gaagcggcgg aagaggagaa ggtggcatga cgacgtcccc cggcaccgtg
     8581 gaatccacga cccctgtgag cggtcagctg cggacggtgc tgtccgcggg tgaacggccg
     8641 gcccgcgcga cggcggtgtc cgccaccctg acccatctgt ggcgggcgat gatggcgttc
     8701 aagcacttcc cggtgcagct gatcgacatc gtcctgatgc cgttgatctt cctgctgatg
     8761 ttcacgtacc tgttcggcgg ggcgttcgcg gactccaccg aggagtacct gcagttctac
     8821 ctcccgggcg tgacggtgca ggcggtcgtc atgatgacgg tctacaccgg cacctcgctc
     8881 aacacggaca tccacaaggg cgtattcgac cgtttccgga cgctcccctt ctggcagccg
     8941 gcgacgctcg cgggcagtct cctcggtgac gtgctccggt acgtcgtcgc cctggcgacc
     9001 acggtgtccc tcgggctgct gctgggcttc cgcgccgacg gcggtttcct cggcgtggtc
     9061 ggcgcgatgc tggtgctgat cgtcttcggg ttcagcgtga gctggatctt cgccgccctg
     9121 ggcgtggtgg ccagcgagcc cgaacgggtc tccgggacca gcatgatcgt gctgtatccg
     9181 ctgctgttca tgagcaacat cttcgtcatg ccggagacga tgcccggctg gatgcaggcc
     9241 atcgtcgacg ccaacccgat gagccacgcg gcgacggcct cccgcgagct catgcacggc
     9301 acggccggct tctgggacgt gggcctggtc ctgtgcgtgt cggcagggct ggtggccgtc
     9361 ttcgcaccgc tgaccatgcg tctgtaccgc aacaagaacg cccactgaca caggtaccgg
     9421 agtgccgctc gcaccgcgct ggagcgtcgt tgagggggtg tgagcggcgc acctactgtc
     9481 cccggagaca catcccggag atttcacaga cacctggaag gggcgtctcc cgtggcccgg
     9541 tacccacagg ctccctcggc accgcacgca caggtccggc cgtcctccgt cgtcggccgg
     9601 cacgatcccc gttaccccga tctggtcggc cgcggcatca acgcccgctt cacccccgac
     9661 cccgacaccg tccgggtggt ggccaccgcg gagcaggccg tgcgggcggt gcaggacagc
     9721 gtgcgcgacg gtacccggct ggcggtgcgc agcggggggc actgcttcga gtcgctcgtg
     9781 gacgaccccg ccgtcaccac ggtgatcgac gtgtccgaga NNtggctttg tcatgactcc
     9841 tcgtaaggat cggagacaac tcctggagag caggctgccg atcggccttc gagcgtcact
     9901 ggagcgaagg ttccgggcac gtggtccacc ggcgttccgc caccgctcga gggactgccg
     9961 gtgtgctgtg gtggcccgag aggagcggag gcgacgacca tgcggatcat cgacatctcc
    10021 agcgcggtgg acgcgtcggg atgggaaccg gacgaagtgc ggcacgaggt gcacagcccc
    10081 cgggagggcg ccgtccacat gagcgaggag atgcggcgtc acttcggtgt cgcgttcgac
    10141 cccgacgagc tgcccgaagg cgagttcctg tcgctcgacc gtctcacgct cacgtcccac
    10201 accggcacgc acatcgacgc tccctcccac tacggctcac gggcgcacta cggcgacggc
    10261 aggccgcgga acatcgacga gctgccactc gactggttct acggcccggg gctgctgctc
    10321 gacctcaccg gctgcgatgg accgacggcc ggggccgggg acctggagaa ggaactggcc
    10381 cgcatcggcc gggtgccgga accgggcacc atcgtcctgc tccgcaccgg cgcctccgag
    10441 cgggccggga ccgagcagta cttcaccgac ttcaccggtc tggacggccc cgccgtcaac
    10501 ctgctgctcg accacggcgt gcgggtcatc ggcaccgacg cgttcagcct ggacgcgccg
    10561 ttcggcgccg tcatccgccg gtaccgggag acgggtgacc ggtcggtgct ctggccggcg
    10621 catgtcaccg gccgccacag ggagtactgc cagatcgagc ggctggggaa cctggccgcg
    10681 ctgccggggt gcgacggctt ccaggtcgcc tgcttccccg tgaagatcac cggcgggggg
    10741 gccggctgga cccgcgcggt cgccttcgtc gacgaatgaa cgttccgggc ggtggccccg
    10801 gaccggcggc cactcagcat cgagagggat catggagccg aacgaatcga catgtcgtat
    10861 ctgcggtggc cgagtacggg agttcttcga cttcggccgc cagccgctgt ccgactactt
    10921 cccgtcggag gaggagctcg acaacgagtt cttcttccgg ctcgcggtcg ggatgtgcgt
    10981 cacgtgcacc atggtccagc tgctggagga ggtgcccagg gaccgcatgt tccgctacga
    11041 ctacccgtac cactcgtcgg ggtcggagcg gatgcgcgag cacttcgcgg cgaccgcccg
    11101 ccggctgatc ggcaccgagc tgaccgggcg ggacccgttc tgcgtggaga tcggcagcaa
    11161 cgacggagtg atgctccgca cggtgcgcga cgccggtgtc cgacacctgg gcgtggagcc
    11221 ttccggcggt gtcgccgacg tgtcccgggc cgagggcatc caggtgcgga ccgcgttctt
    11281 cgaggagtcc acggcccggg agatcgccca ggaacacggg cccgcgaacg tcatctacgc
    11341 ggccaacacg atctgtcata tcccgtacct cgactccgtc ttccgcggta tcgacgccct
    11401 cctcgcgccg gacggcgtct tcgtcttcga ggacccctac ctcggcgaca tcgtcgagaa
    11461 gaacaccttc gaccagatct acgacgagca cttctacctg ttcaccgccc gctcggtgag
    11521 caccaccgcc cagcacttcg gattcgaact ggtcgacgtg gagcggctcc cggtgcacgg
    11581 cggcgaggtc cgctacacca tcgcccgcgc gggccggcgg cagccgagcc cccgggtcgg
    11641 cgagctcatc gccgaggaga gccggcgcgg gctcgccgac ctgacgacgc tggagaagtt
    11701 cggcgcccag gtcaagcggg tctgctgtga cctggtggcc cgtctgcgcg agctgcgcga
    11761 cctcggcttc tacgtcgtcg ggtacggggc gaccgccaag agcgccacag tgctcaacta
    11821 tgcggggatc ggccccgatc tgctgccgtg cgtctacgac accacgccgg ccaagatcgg
    11881 ccgtcggctc cccgggtccc acatccccat ccgctccgcc gaggagttcc gggcccccta
    11941 ccccgactat gcgctgctct tcgcctggaa ccacctagac gaagtccagg cccgagaggc
    12001 ggagttcacg aagcaggggg gccgctggat ccgctcaggg tgaNNtgtct ccgatcctta
    12061 cgaggagtca tgacaaagcc atctgtgcac gaacaccccg gtgtcctggc cgacaacggc
    12121 ctctgcagac ccaagacgcc ggccgggcga cggctgctcg accttctgga gcggtacctg
    12181 ccggccctgg aggcggagag ccgggacaac gaccgcgagg ccactctgcc cgtccacctc
    12241 ttcgaccgga tgcgcaagga gggcgtgctg ggggccaccg tcccggagga cctcggaggg
    12301 ctcggcgtcc actcgttgca cgacgtcgcg ctggccctgg ccaggatcgc cggccgggac
    12361 gcgggcgtgg cgctggctct gcacatgcag ttcagccggg gtctgaccct ggacttcgag
    12421 tggcggcacg gggcaccgtc gacccggctg gaggaggcgg gcgcccccgt ccggctggcc
    12481 gcaccggtgg tcgcgcgcac cacaccgggc ctgaccgtac tggacaactg ggacggaatg
    12541 ggcatgcggt cgtcgggcag tgtggacatc gtcttcgacg gctgtccgnt ggaccgggac
    12601 cgggtgctgc cgcgacggcg agccgggcgt cgcgacgacg cggcgctcgc cgggcagacg
    12661 tcagctcgta cgcatgctgg ctatcactcg gctacgccga ggcgctcgag gatcgccctc
    12721 acggaactgc gcaggcgcgg cggggcgccg gccggggtgc ggaccacggt ggccgagata
    12781 gacgcccggc tgttcgcgct gcacacggcg gtggcgagcg cgttgaccac cgccgaccgg
    12841 ctcgccgacg acctcagcgg cgacctcgcc gcccgcggcc gcgccatgat gacgcccttc
    12901 cagtacgcca agctgctcgt caaccggcac tcggtgggcg tggtggacga ctgcctgatg
    12961 ctcgtgggag gggccggata cagcaactcc cacccgctgg cgcgcctgta ccgcgatgtc
    13021 cgggcgggcg ggttcatgca tccatacaac ttcacggacg gcgtcgacta cctgagcgaa
    13081 gtggcgttgg gccgatgagc ggcgggcgac gcgggaccgg gatccctgga gtcggaggac
    13141 gtggatgaag gcgcgggaac tggcggtgca gggggcgtac acgttcgagc cggaggtgtt
    13201 tccggacgag cgggggctgt tcgtctcacc gttccgggag gatgcgttca cggccgcggt
    13261 cggccacccc ctcttcccgg tgcggcagac gaatcacagc cggtcgcggc gcggggtggt
    13321 gcggggcgtg cactacaccg tgacgccgcc gggctcggcc aagtacgtgt actgcgcccg
    13381 tggcaggtcg ctggacatcg tcgtcgacgt gcgggtcggc tccccgacgt acggccggtg
    13441 ggacgccgtc gagctggagc cgcgtgagtt ccgggcggtg tacttcccgg tcggggtggg
    13501 gcacgccttc gtggccctgg aggacgacac cgtcatgtcg tacatgctgt ccggggagta
    13561 cgtgcaggcc aacgaactcg ccgtgtcggt gctggacccg gccctcgggc tgcccgtgcc
    13621 gggtgacctg gagcctctgc tgtccggccg ggaccgggct gcaccgcccc tggagcaggc
    13681 ccgggccgcc gggacccttc cggagtacgc cgcatgccgg gcggtcgagt cggagctgtg
    13741 gccgccggcc gggtcacgcg gagacgggtg aggcggacat gcgggtcgtg gttctggggg
    13801 cgacgggcag cgtcggtcgg caggtgtgtg cggcgtacca ggcgcacggg tgggacgtgc
    13861 acggggtggc ccgccgcccg gcgccgcacc tgagcgggtg cgggttcacg gagctggacc
    13921 tcgcggccgc cgcgcctggg cggatcgcca cggtgctggg tgatcttccg gcggacgtcg
    13981 tggtcaacgc ggcgggcggc tggggcgaca ccgaggagga gatgacgtac tcgcatctgc
    14041 gactggtgcg acgcctggtg gaggcgctcg cgctgctccc gttccggccc cggctggtcc
    14101 atctggggtc ggtgcacgag tacggtcccg tgccggccgg cacgctgctg cacgaggacc
    14161 tgctgccgga gccggtcacg ccgtacgcgc gcgtcaaact ggagacctcg tcggccgtcc
    14221 tgaccgcagc gcgggccggt gtcctggacg cggtggtgct gcgcgcggcg aacatgtcgg
    14281 gcccgcatcc gccgcaggag agtttcctgg ccgccctgat ggcgcgtatc agcacggcat
    14341 tcgcgcacgg tgggcggctg gagttgagcg tcgcggacgc acggcgggac ttcatcgacg
    14401 tgcgggacgt cgcacaggcg gtggtgcgtg ccgggcgggc tccggcggtc ggcgggctgg
    14461 tcgtcaacat cgggcgcggg gacgccgtgc cgatcggtga tctggtcggc tggctgctgg
    14521 aggccgccgc cttcccggag gaccgggtcg accgccggga ggcgccggtg cggagcaagg
    14581 gcggcgactg gacccggctg gacatcgggc gggcccggcg gttgctgtcc tgggcgccgc
    14641 gcatcggcct gcgggactcc gtccacagca tgtggcggac cgcgcacggc gccccggcct
    14701 agNNcctccc cggcgctccc actgtgactt tctcacatcg agacgtgatg aactaatccc
    14761 agcaagtgcc gtacacactt tcatggcggg cattcacttg cgaggatgga gcgagcaaac
    14821 ggggccgccc gaggacatcc ttcggccgcc ggaaatatgc cacctgctga cgcgatcgga
    14881 acgccacaga gggagcacac cggcaatgca gatcaatatg ttgggcccgc tcgtcgcaca
    14941 tcacaatggc acgtcggtga ccccgatagc cagaaagccc cggcaagtat tctcactgct
    15001 cgctctccag gcaggaaccg tcgtgccggt gcccgcgctg atggacgagc tctggggaac
    15061 ccaacccccg gcgagcgcgc tgaccaccct tcagacctac atccttcaag tgcgccgggg
    15121 catcaccgtg gccctcggcg cgagccacaa cggacccgcc aaggacgtgc tgcgcacctg
    15181 ctacggcggc tacctgctcg acgtggaccc caccaacacc gacgtgtacg ccttcgagcg
    15241 tctcgccgag gagggcaagc gggcgtgcga gcggggagag ctcgacctgg cctccgcacg
    15301 cttccgccag gccctcgacc tgtggcgcgg agacgcgctc gtggacgtgc acgccggcat
    15361 gcggatcggc atggaggtgg cgcgcctgga ggagagccgg ctcggcgtcc tggaggcccg
    15421 catggagacc gacctgaggc tgggccggca cgcgggcctg ctgcccgagc tgtcggcgct
    15481 caccgcccgc caccccatgc acgagaacct gtgggcccaa ttcatgatcg ccctccatcg
    15541 ctcgggccgc acgagccagg ccctcgaagc cttcatcaaa ctccgcaaga cattggtgaa
    15601 cgagctgggg gtggaaccgt ccgcccgtct ccagcacctc cagcacgcga ttctgcgggc
    15661 cgaccccggc atcgaccgga acggtccgga agtcccggca gccgcgtccg tcgcgcttgc
    15721 ctgaccgcgc cccgacaagg agtcacgtgt ccacctacgt ctggcaatac ctcaatgaat
    15781 accgggaaga acgcgccgac attctcgatg cggtggaaac cgtattcgag tccggccagc
    15841 ttattctcgg gaccagcgtc cgctctttcg aggaggagtt cgccgcttat cacggactgc
    15901 cgtactgcac gggcgtcgac aacggcacca acgcgctggt cctcggcctg cgggcgctcg
    15961 gcatcggccc gggggacgag gtcgtgacgg tctccaacac cgcggccccc accgtggtgg
    16021 ccatcgacgc cgtgggcgcc acccccgtct tcgtcgacgt gcacgaggag aactacctca
    16081 tggacaccgg ccggctccgg tcggtgatcg gcccgcgcac ccggtgcctg ctgcccgtcc
    16141 acctctacgg acagagcgtg gacatgaccc ccgtgctcga actcgccgcc gagcacgacc
    16201 tgaaggtgct ggaggactgc gcccaggccc acggtgcccg ccgtcacgga cggctggtcg
    16261 gcacccaggg gcatgcggcg gccttctcct tctacccgac caaggtcctc ggtgcctacg
    16321 gtgacggcgg cgccgtcgtc acgccggacg cggaagtcga ccggcggctg cggcggttgc
    16381 gctactacgg catgggggag cgctactacg tcgtggacac ccccgggcac aacagcaggc
    16441 tcgacgaggt gcaggccgag atcctgcgcc ggaaactgcg ccgcctcgac gcctatgtcg
    16501 agggccgccg ggccgtcgcc cgccgctacg aggagggact cggtgacctc gacggcctgg
    16561 tgctgcccac gatcgccgag ggcaacgacc acgtctacta cgtgtacgtg gtgcgtcacc
    16621 ccgaacgcga ccgcatcctg gaggcgctca ccgcctacga catccatctc aacatcagct
    16681 acccctggcc cgtccacacc atgagcggat tcgcccacct cggctacggc cccggcgacc
    16741 tgccggtgac cgaacggctg gccggcgaga tcttctccct gccgatgtac ccctcgctgc
    16801 gtcccgacgc gcaggagaag gtgatcgacg cggtgcggga ggtcgtcgga agcctgtgag
    16861 ctaggccggg gcgccgtgcg cggtccgcca catgctgtgg acggagtccc gcaggccgat
    16921 gcgcggcgcc caggacagca accgccgggc ccgcccgatg tgcagccggg tccagtcgcc
    16981 gcccttgctc cgcaccggcg cctcccggcg gtccgacNNg gatccgcacc gggtacacgg
    17041 cacgggaccg cccaccgcgc ggtgcgcggt gggcggtccc gtgccggtcg cggccggcgg
    17101 atcagcgcag ccagacgggc agttcggtga gccgcgccgt ctgggccccc ttccggcacc
    17161 accgcaactc gtcgtacggc acggccagtc gggcctcggg gaacctgctg cgcagtacgc
    17221 cgatcatcgt gcgcgactcc agctgggcga gctgctcccc gatgcagtag tgcggcccgt
    17281 cgccgaaggt gagccgccgc cacgagggac ggtccgggtg gaaggcgtgc ggggcgtcgt
    17341 gatggcggcc gtcggtgttg gtgccctcga tgtccaccag caccggcgct ccgcggggca
    17401 gccggacgcc gccgatggtc acctccgtgg cagcgaacct ccacaacgtg tagggcaccg
    17461 gcgggtggta gcgcagcgcc tcctccacga accgggagac ggcgtcctcg tcggcatccg
    17521 ccgcgaggcg gcccgccagg acctccgcga gcaggaagcc caggaaggag ccggtggtgt
    17581 cgtggccggc gaagatgagc ccggtgatca tgtagacgag ctggtcgtcg gagaccgagc
    17641 cgaactcggc ctgcgcgcgc tcgtacagca cgcgggtcat ggtcggggtg tcgttccgcc
    17701 gggctgagtg cacggcttcg aggagcaggc tctccagggc cgaggtgtcc ggcacgcccc
    17761 cggcagggtc cgtgccgtca cccccgccgc tctgcgggcc gccgaggccg agtgccttga
    17821 gaacgctgac ggcctcgcgg gccatcgccg gatcggtgac cggcacaccg agcagctcgc
    17881 agatgaccaa cagcgggaag tggtacgcga agccgccgat cagctcggcc ggtttgcccg
    17941 accggccgga ggcgtcggcg agttcggtga gcagccggcc ggcgatcgcg gcgatgcgat
    18001 ccgtccgctc ggccagccgg cgcgggttga acgcaggtgc gtggatgcgg cgcaggcgcc
    18061 ggtgggcctc gccgtccacg gcgatgagcg tgaacggacg cagctccgga acggggatgt
    18121 cgagaccgtc gtccaccccc cgccaggcgg cgggggcgag gtcggggtcc ttcacgaacc
    18181 ggggatcggc cagcacctcg cgggcgaggg cgtcatcggt gatgacccag gcgggtccgc
    18241 ccgcgggggc gttcacctcg acgaccgggc ccgcctcccg gaaggcgtcg tgcacctcgg
    18301 gcttgcgctg catggtcatc atgggacacg cgaacgggtc gacggccacc cggggcgcct
    18361 cgccgctcac gaggcaccgc ccgccgccgc ggggtacccc tcccgcagtt cgaccaccga
    18421 gaagccggcc ccgtgcgggt cgagcaggtc cgcccgccgc cccctgggcg tgtcggcggg
    18481 ctcgttctcg acggagccgc cgagttcaac ggcgcgccgg accgtcgcgt cgcagtcgtg
    18541 cacggcgaac agcacggccc agtgcggccg taccgcgccg gtgacgccca gctcctgggt
    18601 gccggcgacc ggtgtgtcac cgatgtgcca gaccgggtcg gtgacgccct tcagtccggt
    18661 gtcggccgga gccaggccga gggtcgccgg gtagaagtcc cgggcggccc cgatgccgtc
    18721 ggtcaccagc tcgacccagc cgaccgagcc gggcacgccc gtcacctccg cgccctccat
    18781 gactcccttg cgccagaccg cgaacgcggc cccggcgggg tcggcgaaga ccgccatccg
    18841 gccgaggccg aggacgtcca tcggagtcat gatgacctcg ccgcccgccg tctcgacccg
    18901 cttggtcagt gcgtcggcgt cgtcggtggc gaagtacacg gtccagatgg ccggcatgcc
    18961 gtgctggtcg ttcccgggcc cgtacggccg gtggtagggg gtgtcgatct ggtggcgggc
    19021 gaccgcggcg accagcttcc cgtcggagct gaacgtcgtg tatcccccgg cgcccgggtc
    19081 gctgaccacg gtggcggtcc agccgaacag gccggtgtag aagtcggccg aggcggcgac
    19141 atcgggcgaa ccgaggtcga accatgcggg ggcgccgggc gcgaacctgg tcacgaatcg
    19201 ttcctttcga tggatcggca cacgagcgtc tgcgctcgcg gatgagacgg acatctcgcg
    19261 gatgagacgg acatgcgggc ggggcgggcc gccgccgtca gtgcgcggtg tcgccgacgg
    19321 cggccgcgcc ggcctcccag agcttcgccg cgaggccggc gtcggcggtc gggccgctca
    19381 ccggggacag ccgccggtcg ctgtagtagc cgcccgtggt caactcctcg gccggcgcgg
    19441 acgccagcca cacgagggtg tcggcgccct tcgccgcgga gcgcaggaag gggttgaacc
    19501 ggaagtagga cgaggcgacc gtgccccgtc cgatgcgggt gcggacctca ccggggtgat
    19561 agctgaccgc cagcacgtcc ggccagcgcc tggcggcctc cgccgcggtc atgatgttgg
    19621 cctgtttgga cgtgccgtac gcctggccgg cgctgtagcg gtgacggtcg ccgttgaggt
    19681 cgtccgggtc gatccggccc tgggtgtacg cgtcggacga ggtgaggatc agccgcccgc
    19741 ccgcgagccg ctcccgcagc agccgtgcca gcaggaagcc tgcgaggtga ttgacctgga
    19801 tggtggcctc gaacccgtcc tgggtcgtgg tgcgcgacca gaacatgccg ccggcgttgc
    19861 tggccatgac atcgatgcgc gggtaccggt cccgcagccg ctcccccagg tcgcgtacct
    19921 ggcgcagctc ggcgaagtcc gcgcggaagg cgtccggggc cgggccggcg gtccgggcca
    19981 cctcgttcgt gacggtccgc agacgctcgg ggtcccggcc gacgagcacg acgcgggccc
    20041 cctggcgggc gaccgcgagg gccgccgccc ggccgatgcc ggacgtggcc ccggtgacca
    20101 gcaccgtccg gcccgacagg ccgccgcgtg gtgtcccgtg gtgcggggtg gaggccgtca
    20161 tgccgccgct cgcagcctct cgttgacgaa gatcagcatg ctatgcggcg tcctgacctc
    20221 cgccagttcc tcctcgggca gcttcacgcc ataggtccgc tcgatgtggt tgaccgtttc
    20281 caggacggcc agggagtcga gcccgaggtc ctcgaaggtc acggtgtccg cgtccgcaag
    20341 gtcggggacc tcgtcctccc ccaggctctg ccgcatgatc tcccgcagtt ccgccaggct
    20401 gagctcagcc atccctgctc ctcagtaccg gttgctgcac gacgtgtacg gcccggtcgg
    20461 gaccgcggcg accaccctcg gttccgcacg tccagtcgta ctggagcggc ggtggaccga
    20521 cggttgtccg ctctgcctca agacgcgcgg aacaggttgg gcacggcgcc ggccggcagg
    20581 cgcacgcggc cgggccagga ccgggccgcc cgaggccatc acacgaccca aggggtaacc
    20641 atggacgcgc tcccggcgga cgacgcgccg acgaccgagt cggcggattg tacggacccc
    20701 ggcatctacc tccaggtaca gcggttctac gcccggcaga tgcaactcct ggatgacggc
    20761 agggccgagg actgggcgcg cacgttcgcg caggacggcg tcttcgaggt gggcggcgag
    20821 gccgtccgcg gggccgcgga catcgcgcgt gcggcacggc ggaccacgga ccggttcgcc
    20881 gccgaaggga tcacccggcg gcactggatc ggcatgctga ccgtcgacgg caagcccgac
    20941 gaggtcacgg cccgcagcta cgcggtggtg ctggagacgc cgcgcgacgg cgacccggtg
    21001 ttgcgccgca gcacggtgtg cacggacatc ctggtgcggg aggcgggcga gtggcgcgtc
    21061 aaacaccgca ccgtcacccg ggacgggctg gactgaccat gctgtgctct cccggccctc
    21121 tcggtgcgcc ggcacagcgg cgccgcgatg accgcccaga tcgcccggtc cgtcctcgcc
    21181 cgggacggcc tgggcagcgg catggaccgt ttctgggcgt ggtacgccga ccgctcggcg
    21241 caggtcgtgc accgcaccga gcggattccg ctggacgacc tcaaggggtg gagccgccac
    21301 ccggtcactg ggaccgtctc ccatcacacc gggaggttct tcagcatcga gggactggac
    21361 gtgcacatcc cgggcgcccc cgtgccacgc tggtcccagc cgatcgtgaa ccagcccgag
    21421 gtgggcatcc tcggcttcct ggtgaaggag cgccacgggg tcctgcactg cctcgtccag
    21481 gccaagttcg agccgggcaa ccccggcggg cttcagctct cccctacggt ccaggccacc
    21541 cgcagcaact acacgcgggt gcacggcggc aaggccatcc cgtacctgga gcacttccgc
    21601 gacaccgccg aacggcaggt ggtcgccgat gtgctccagt ccgaacaggg ctcctggttc
    21661 taccgcaagc gcaaccgcaa catgatcgtc caagtgatcg acgaggtccc gctgcacgag
    21721 gacttccact ggctgacgct gggtcagctg caccggctgc tgggggtcga gaacctcgtg
    21781 aacatggacg ccaggacggt gctggcctgc ctgccgttcg cgagtgaggg agcgcacccg
    21841 ctggccgacg cggagccggc cggagccgac ggccccggag gtggccaccc ggtggtcccc
    21901 gctcgacccg acggcggcga gggccgggta gacaccggtt tccaccgctc cctcgtgcgg
    21961 tcgtgcgcgg cggccgaggg cagcctgcac agcaccgtgg acatcgtcag ctggatcgcc
    22021 gacctgcgca gccgtaccga cgtggtcacc cgcccggctg cgctgaacgc gctgccgcac
    22081 tggtacgagc gggacggcgc gatcgcccac gagagcgggc gcttcctgga ggtgatggcc
    22141 gtcgacgtga cggccgcctc gcgggaggtg cccggctgga gccagccgat gatcgaaccc
    22201 aaggaccaag gggtcgcggc tttcctggtc cgacggatcg acggggttct ccacgtcctg
    22261 gcgcacgcgc gcgtggagcc cggctacgtc gacgtggtgg agatcgcgcc caccgtacag
    22321 tgcacccccg gcagtctgca cgccctgccc gccgaggcca ggccccgctt cctcgacgcc
    22381 gtgctggagg ctccacccga gcgcgtgcgc tacgcgaccg tcctcgcgga ggagggaggg
    22441 cgcttctacc acgcggtgaa cacctacatg atcgtcgaag ccgaccatga catcccggac
    22501 ggtggcgaat accgctggct gacgctccac caactggtcg ggctgctgcg tcactcccac
    22561 tacgtcaacg tccaggcccg caccctggtc gcctgtctgc acagcctgtc cgtgggctcg
    22621 cccgtaaccc gctcagccgt gccgtccgcc ccgccccgga ggtgagttcc ccgtgcgcgt
    22681 cctgttcgcc accatggccg cgcggtccca tgtctacgcc caggtcaccc tggcgtcggc
    22741 actgcggacc gcggggcacg aagtgctcgt ggccagccag cccgacgtcc tcgacgacat
    22801 cgtccgggcc ggtctcaccg ccgtgcggat cggggaggac ctcaacatcg aggaggagac
    22861 ccgggaggcc aacgccagct tcgaggacga ccgcaacctc gggggcctcg ccatgagcaa
    22921 ctcccgtgat gaccccttcc cgtgggacca cgcgctcggc atgttcaccg cgatgaccgc
    22981 catggtcttc cagaacgtgt gccccgagcc catggtcgac gacctcgtcg gcctcgcccg
    23041 cgactggcgg ccggacctcg tggtctggga tccgctgacc ctggccgggc cggtggccgc
    23101 ccggctcagc ggggcggcgc acgcccggct gctgttcggc ccggaccaga tgggccggaa
    23161 caggacggcg ttccgcgccc tgctcgaccg gcaaccgccc gagctgcgcg acgacccgct
    23221 ggccgagtgg ctcacctgga cgctggagcg gtgcggcggc agcgccgggg acatgagcga
    23281 ggagctggtc ctcgggcagt ggacgatcga ccccacaccg ccgtcgatgc gcatccccct
    23341 ggacctgccc tgcgtgccgg tgcgctacgt gccgtacaac gggccctccc tgctccccgg
    23401 ctggctgcgc gagccgcccc gccacccgcg gcgcctgtgc ctgacgctcg gtgtgtccct
    23461 cggcgaggcg acgggcgccg gcacggtcgc cgcctccgac gtcctggcgg ccgtggacgg
    23521 cctggacgtg gaggtcgtcg ccaccctgcc gcgggaactg cgcgaggagc tcggcaccct
    23581 gccggcgaac gtgcgggccg tggacttcgt cccgctgaac gccctgctgc cgtcctgctc
    23641 gggcatcatc catcacggcg ggtccggcac gttcatgacg gccctggtgc acgcgatacc
    23701 gcagctgatc gtgcctgaca tgatgtggga cgccatggag aaggcacacg gcctggcccg
    23761 cagcggtgcg ggcagttacg tggacgcgcg ggacgtctcg ccggaactgc tgcgcgagcg
    23821 cgtcctcgcc ctgctcgacg atccgtccta cgccgccggg gcacgccggg tgcgcgccga
    23881 gatcgtcggg acgccgagcc cgaacgacat cgtgcccgtg ctggagcggc tgaccgccga
    23941 gcaccgggcc ggcggggcgg aggggggccc ggcgctcaag tcgccttcca ccggcggtgc
    24001 ctagNNtcca ccggcggtgc ctagcctcgc cgcatggaga acacacagcg atccgtgatc
    24061 gtgaccggcg gcggctccgg catcggacga gccgtcgccc gcgccttcgc cgcccggggc
    24121 gaccgcgtcc tcgtcgtggg caggaccgcc ggtccgctgg ccgagacggt ggacgggcac
    24181 aaggacgcgc acacgttggc cgtggacatc accgaccccg cggcgccgga ggcggtcgtc
    24241 cgggaggtgc gcgagcggct cggcggcgtg gtcgacgtgc tcgtgaacaa tgccgccacg
    24301 gccgccttcg ggcacctggg agagctgcac cgcaccgcgg tggaggcaca ggtggccacg
    24361 aacctcgtgg cccccgtgct gctcacccag gccctgctcg gccccctgga gaccgcttcc
    24421 ggcctggtgg tgaacatcgg ttcggcgggc gcactcggcc ggcgggcctg gccggggaac
    24481 gcggtgtacg gggcggccaa ggccggcctg gacctgctga cgcggtcctg ggccgtggaa
    24541 ctcggtcccc gcggcattcg cgtggtcggt gtcgccccgg gagtgatcgg gacgggcgcg
    24601 ggggtccggg ccgggatgtc ccaggaggcg tacgacgggt tcctggaagc catggggcag
    24661 cgcgtcccgc tcggccgtgt gggccggccc gaggacgtcg cgtggtgggt ggtgcggctc
    24721 gccgatcccg aagccgcgta cgccagcggt gccgtgctgg ccgtggacgg gggtctctcg
    24781 gtgacgtgag gcccgcccgg ccggacaccc gcaggtcgcc ctccgctcgc cggagggcga
    24841 cctgcgggtg tccggccagg gacgcggcgg gccccgcccc tagggagtcg ggacagggcc
    24901 cgtgcgggct cgggacgctc gcctcaggcg ctggactcgg cgtactgcct ggccgcttcc
    24961 agggtcagca gactgttgcg gcccagggcc cggcggacga agtccacggc gtccgtctca
    25021 ctcgcccccg caccgaggac gccggggatc gccgagcggg ccacggacac ggtgtgggcc
    25081 gacgtgacgg cgatcccgtc cccgtcgtcg gcgggacgga ccgaccaacg gccgagatgg
    25141 agcgcgagca gcggcggcgt gcgcagctgc ttgtagacga tgacgcggcg ttcggggaag
    25201 cacactcgca ccgacgcggt ggtgtgcacc gagccgtccg cggtgagggt gtccatctcc
    25261 atgtgctgga gccccggttc ctcctccttg accgcgatcc gcgcgacgtg ggagagccgc
    25321 ttcttccaga ggtcgctgcg gtggaggaag tcgtagacgt cctcggcacg gccgcggacg
    25381 acgacggtgt cctcgaaggt cgtcggcgcg gtgccgtcgg gtcgttccag cgcggtgcgc
    25441 agggacgcca gttccgcttc gctgttgcgg tccacggccc ggtggatcca gccgatcgtc
    25501 tccgggtcgt cgtccacggc ccggaagtcg tgcgtcagcc gcacccgggt gccgccgtcg
    25561 ccggcttcct cgacgatcca ttcgccgccc atggcggcga cgggatgggc ggacacctcc
    25621 tgccggaaac ggatgcgccg ggcccgctcg tcgagctcgc gccgcgacgt ccaggtgcgc
    25681 agcgagccgt tggcggtggc ccagatgcgg atgcgctcgc tggagccggt gtgctcgacc
    25741 tgttcgacgt ggacactggg cgggaacacg gcgggccagg cccgtgcgtc ggccagcacg
    25801 gcgaacacgg cgtccggcgc ggcggaggtg tggatctcgt gctcggtctg ctgaagcggc
    25861 aactcggaca tctgccttcc tgagctcggg tcgcggacgg tcagtagctg ccgaggccac
    25921 cacagacgtt gatggcctgg gccgtgatcg agtcggcgct gtcggaggcc aggtagtgca
    25981 ccatcccggc cacctcctcg ggcatcgagt agcgtccgag ggggatcttc gcctggaact
    26041 tctccaggac gtcgtcctcg gtgatccccc agaaggcggc gtagcgctgc cgcacgccct
    26101 gtgccatggg cgtctcgacg tacccggggc agacggcgtt gacggtgatg cccgtcttgg
    26161 ccagctccag cgcgacggcc ttcgtgaagc cgatcaggcc gctcttggag gcggagtagg
    26221 gggcgccgag ggccactccc tgcttgccgc cggtggaggc gatgctgatg atccggcccc
    26281 agccgtgctc ctgcatggcg ccgccggtga ggacggcgcg ggtgacccgg aaggccccgc
    26341 tgaggttggt gtcgacgacg tcgagccaca ggtcgtccgt gatctcggcg gtcacgcctc
    26401 caccgccgcg gccggcgttg ttgacgacga tgtcgatcgg cccgaagcgg ttccgggccg
    26461 tttggaccag ccggtcgacg tcggcggtgc tccgcacgtc gcagggcgcg ccgtccacct
    26521 ccagtcccga tgcctgaagt tccttcacgg tgccggtgat ggcgctctcg tcacgagcgc
    26581 acaggaacac ccgggtcccg tcctgggcga gcttgcgcac caccgcgaga ccgatgccgc
    26641 tggttccccc ggtgacgagt gcgacccggt cggctgcctc ggacatggtc ctcccttcga
    26701 cggagggccc accctcacat ctcgcgctcg agccgcgctt gacgacccgg cttccagagg
    26761 gggtcgagcg gcgccgcaga gcctcggagt ccggcgtgac cgcacctgtg cggactcggc
    26821 cgcaccgtct caccgacgtc caccccacac ctggaccaac ggacccgtgg agcagcgatg
    26881 ccacagccag aaccgaacga cgccggctcc gggtcggtga cgttcgtcaa ccgattcacc
    26941 ctgagcggat ccgccgagga cttcgaggcg gcgttcgccg aaacggccga gttcctgtgt
    27001 cgccggcccg gcttccgctg gcacgccctg ctggtgccgg ccgacaccgg tcccggctcg
    27061 gcggacgccc gcccgcagta cgtgaacatc gcggtctggg acgacgaggc ctccttccgc
    27121 gccgccgtgg cacacccgga gttcccggcc cacgcggccg cccttcgggc cctgagcacc
    27181 agcgaaccga ccctgtaccg gcaccgtcag atccgtgtcg cgccggacgt cccggccgtg
    27241 agcgggcccg gagggcggac gacgtgaacc ggcggatcgt catcaccggg atcggcgtgg
    27301 tggctcccgg cgccgtcggg accaagccgt tctgggagct gctgctgtcc ggaaccaccg
    27361 ccacccgcgc catcagcact ttcgacgcca cgcccttccg ttcccgtatc gccgccgagt
    27421 gcgacttcga tccggtggcg gcggggctgt ccgcggagca ggcccggcgc ctcgaccggg
    27481 ccgggcagtt cgcgctggtc gccggtcagg aggcgctcgc cgacagcggg ctgcgaatcg
    27541 atgaggactc cgcgcaccgg gtcggggtgt gcgtgggcac cgccgtcggc tgcacgcaga
    27601 aactggagtc cgagtacgtc gctctcagcg cgggcggagc gcactgggtc gtggaccccg
    27661 gccgggggtc gcccgagctg tacgactact tcgtgccgag ttccctcgcc gccgaagtgg
    27721 cctggctcgc cggggcggag gggcccgtga acatcgtctc ggccgggtgc acctcgggga
    27781 tcgactccat cgggtacgcc tgcgagctca tccgcgaggg gacggtggac gccatggtcg
    27841 cgggaggcgt ggacgcaccc atcgcgccga tcacggtggc ctgcttcgac gccatcaggg
    27901 cgacctccga ccacaacgac acccccgaga ccgcctcgcg tcccttcagc cgcagccgca
    27961 acggctttgt gctgggcgag ggcggtgcga tcgtggtcct ggaagaggcg gaggcggccg
    28021 tgcgcagggg cgcgcggatc tacgccgaga tcggcgggta cgcctcacgc ggcaacgcgt
    28081 accacatgac cgggctgcgc gcagacggcg ccgagatggc ggcggcgatc accgcggccc
    28141 tcgacgaggc ccgccgcgac ccctcggacg tggactacgt caacgcccac ggaacggcga
    28201 cgaagcagaa cgaccggcac gagacctccg cgttcaagcg ctccctgggg gagcacgcgt
    28261 accgggtgcc catcagctcc atcaagtcga tgatcggtca ctccctgggc gctgtcggct
    28321 cgctcgaagt ggcggcgacc gcactggccg tggagtacgg ggtgatcccg ccgaccgcga
    28381 atctgcacga cccggatccg gaactcgacc tggactacgt gccgctgacg gcacgagaaa
    28441 agcgggtgcg gcacgcgctg acggtgggca gcggcttcgg cggcttccag agcgccatgc
    28501 tgctgagccg tctcgagagg tgagctccat gacaggtacc gcggcacgga ccgcgtcttc
    28561 gcagctccac gcatcgcccg cgggccgacg gggcctcagg ggccgcgcgg tggtgacggg
    28621 tctcgggatc gtcgccccca acgggctggg ggtgggcgcg tattgggacg ccgtcctgaa
    28681 cggccgcaac ggcatcggac cgctgcggcg gttcaccggc gacggccgcc tgggccggct
    28741 ggccggtgag gtgagcgact tcgtccccga ggaccatctg ccgaagcggc tgctggcgca
    28801 gaccgatccg atgacccagt acgcgctggc cgccgcggag tgggccctgc gggagtccgg
    28861 ctgctccccg tcctcgccgc tggaggcggg ggtgatcacg gccagcgcgt ccggcggctt
    28921 cgccttcggc cagcgggagt tgcagaatct ttggagcaag ggaccggccc acgtcagcgc
    28981 ctacatgtcg ttcgcctggt tctacgccgt caacaccggg cagatcgcca tccggcacga
    29041 tctgcgcggc ccggtcggcg tggtggtggc cgagcaggcg ggcggcctcg acgccctcgc
    29101 ccacgctcgc cgcaaggtcc ggggcggagc cgagctgatc gtctcgggcg ccgtggactc
    29161 gtcgctgtgc ccgtacggca tggcggccca ggtgaagtcc ggccggctga gcggctcgga
    29221 caacccgaca gccgggtatc tgccgttcga ccggcgggcg gccggacatg tgcccggcga
    29281 gggaggcgcg atcctcaccg tcgaggacgc ggagcgggcc gccgagcggg gcgcgaaagt
    29341 gtacgggtcg atcgccgggt acggcgcgag cttcgacccg ccgcccggct ccggccgccc
    29401 ctccgccctc gcccgtgccg tcgagacggc gctggccgac gccgggctgg acggctccga
    29461 catagccgtg gtgttcgccg acggcgcggc cgtccccgaa ctggacgcag ccgaggcgga
    29521 ggctctggcg tcggtcttcg ggccgcgccg ggtcccggtg accgtcccca agactctcac
    29581 cggccggctg tattcgggcg ccgggccgct ggacgtggcg accgcgctgc tggcgctgcg
    29641 ggacgaggtg gtcccggcga ccgcccacgt cgaccccgac ccggacctgc cgctcgacgt
    29701 ggtgaccggg cggccccggt ccctggccga cgccagggcg gccctcctcg tcgcccgcgg
    29761 ctacgggggc ttcaacagcg ctctggtggt ccggggggcg gcgtgagcgt gccgcagggg
    29821 gcgcccgggg acctttacgt ggccggttgc ggcgtctggc tgcccccgcc ggtgaccacg
    29881 gaacaggccc tggccgccgg ccactgcgac cgcaggctcg cctcctcgac gcggatgctg
    29941 tcggtggcgg tcgccgacaa ggagacaccg gccgaaatgg cggccttggc ggcccagacc
    30001 gctctggacc gctccggcgt cgcaccggcc cacgtcgacc tcgtcctgca cgccagtctg
    30061 tacttccagg ggcaccatct gtgggctccc tcctcctacg tccagcgggt ggccgtcggg
    30121 aaccgctgcc ccgccatgga ggtgcggcag gtgtccaacg gcggcatggc cgccctggaa
    30181 ctggcccgcg cgtacctgct tgccgccccg gaccgggtgg ccgctctcat cacgacaggc
    30241 gaccggatgc atccgccggg cttcgaccgc tggagcagcg accccggcac ggtgtacgcc
    30301 gacggtggta ccgccctcgt gctgtcccgg cagggcggtt tcgcccggct gcgcagcctg
    30361 gtgacggtct ccgaaccggt gctggagggc atgcaccggg gcgggcaccc gttcggcccg
    30421 ccgtctccgg aggagcagcg ggccgtggac ctggacgcgc acaagcgggc gtacgtggcc
    30481 gaggcgggaa gctcgttcag cgtcgcccgg gtctcggcgg gccaggagga ggctctgacc
    30541 ggcgcgctgg aggcggccgg ggccggactc gacgacatca gccgggtcgt gctgccgcac
    30601 atggggtggc gccggctgag cgccgcctac ttcaacaagt ggcacatcca acccgagcgg
    30661 accacttggg agttcgggcg gcggaccggc cacctggggg gcggtgaccc gatcgccggg
    30721 ttcgaccacc ttgtgggctc cggccgcctc gccccggggg agctgtgtct gctggtcagc
    30781 gtcggcgccg gcttcagctg gtcgtgcgcc gtcgtggagt tgctggaacg cccgtcgtgg
    30841 gcggccgccc cggccgcccg gtgaggagcc cgtcatggat gcgcccgcga ttctcctgat
    30901 gttccccggg caggggtccc agcatgcgcg gatggccgtc ggcctgtacg gatccgaacc
    30961 ggccttcacg gccgccatgg acgaggtctt cgacgcgtac gacgacgccg gcgacagtga
    31021 gggcgggcgg ctgcgtgccg actggctgag cgaccatccg gccgtgccat tggaccacgt
    31081 cacccggtcc cagccgttgt tgttcgcggt ggactacgcc ctcggccgga tggtgatggc
    31141 cacgacgggc cggccgtggg ccctgctcgg gcacagcgtc ggcgaaatgg cggcggccgc
    31201 gctcgccggg gtgttcacgc tgcgcgacgc ggccggcctc ctgctggacc gggtgcgacg
    31261 gctggcccag gcaccgcccg ggggaatgct ggcggtcgcc gcggccgagg acgtgctggg
    31321 cccgtatctc gggaatgggg aggtggtggt cgcggccgtc aactcgcccc gccagaccat
    31381 cctcgccgga cccgtcgcat cgctcgccgg ggtcgcccgg gcgctgcggg aggcagggct
    31441 tacgtgccgt gaggtgccct cgctgaccgc cttccacagt ccgatgctgg ccccgatcgc
    31501 ggcgggggcg gccgagcggt tcgcatccac gcgcgtggcg ccgtccatcc ccctccgctc
    31561 cgggtaccgg ccgggtgcgg tgaccgggca actggccgcc gacccgtcgt actgggccgg
    31621 gcatcccctg gagacggtcc gcttctggcc ggcactggac gcgatgctcg gctcccgcac
    31681 gggcgtcgtc tgcctggaga cggggccggg gcaggggctg agcaccatcg cccgccgcca
    31741 tccgacggtg cggttcggga agaactcggt ggtgccgctg ctgccgccgc aggccggcac
    31801 cgccgaggtg gaccggacgt ccgtggcggc ggcgctggcc gcggtgcgcg agcagggcac
    31861 cgtgctcagt gggcgacccg ggcggtgacg aagcggacgg gcacgtcgat ggcgagggcc
    31921 ccggtggcgt cgctcagctt gtcgagtccc tcgacgagcc gtgcgcgcag ttccgttcgc
    31981 tgggcctgcg ggaggttctg ccacagcaga cgcatgccct gggtgtggga ccagtccacc
    32041 cacgcctcgc tggacagggc cgtcatccgc accggctcgt cggtgacggc gaccgaggtg
    32101 tagccgcagc gttccagggt gcggaggaga tcctcggccc gctccagcca gctgttgaac
    32161 cgccggacca gcgcctcggg ccgccactgc tcgggcaggt gctccagcag cgcctgcggg
    32221 atgagcgggg tgaactccgg tggcaggaac gggaacgtgc cggcgcggaa gaccgggctg
    32281 gtgaacgcga tcctgccgcc gtggtccagg attccggcgt agcgcgccag cgcccccacc
    32341 gcgtccggca ggaagatgac gctgtagctc cccatgacca ggtcgaagga gcgcgccggg
    32401 agttcgggcg tctccgcgtc catcacatcg agggcgatat tccgcagacc gcgttcggcg
    32461 gcttccttgc gagcttcctc gatcattccg ggagcaatgt cgattccgtg gacgcgcccc
    32521 tgaggaccga ccttttccgc agccggaaaa aggcatgcgc cgcgcccgca gccgatgtcg
    32581 agcactcgtt caccggtgac cggctccgag atttccacca ggggccgacc catgggcgtg
    32641 aagaattcca ctcccagtcg gtcgtaggtc gacgacgact ggtcgaaggc ctgagttacc
    32701 tgctctttgt aggacgaatc ctgcaccgtc ggctcctgcc tctNNgcgat tcgggccctt
    32761 ccccgcttac cagtgttcga cccgtacttg aagggcggtg gagtgccgtt cgaggcgtcc
    32821 cggaaacact tgtacgccgc cgcagggaga aacaacaatt gttgacgcgg tcgccgatgg
    32881 tgtcaccgtt tccggtacgg gagggaaaac catgagcacg cagatcgatc tggtccgccg
    32941 catggtggag gcatacaaca cgggaaaaac cgacgatgtc gcggagttca ttcacctcga
    33001 gtacctgaac cccggcgcgc tggagcacaa cccggagctg cgcggcccgg aggcgttcgc
    33061 ggccgccgtc acctggctca agtacgcctt ctccgaggag gcgcacctgg aggagatcga
    33121 gtacgaggag aacggcccgt gggtccgggc gaagctcgcc ctctacgggc ggcacgtcgg
    33181 caacctcgtc ggcatgccgg caaccgggcg ccggttctcc ggtgagcaga tccacctcat
    33241 ccgcatcgtc gacggcaaga tccgcgatca ccgcgactgg cccgactacc tcggcaccta
    33301 ccgccagctc ggcgagccct ggcccacccc cgagggctgg cgcccctgac cccccatcac
    33361 cccgccgacg ccacgacagg agcacggaca caccatgaca gccgaaccga cggtcgcggc
    33421 ccggccgcag cagatcgacg ccctcaggac cctgatccgc ctcggaagcc tgcacacgcc
    33481 catggtcgtc cggacggccg ccaccctgcg gctcgtcgac cacatcctgg ccggggcccg
    33541 caccgtgaag gccctggcgg ccaggacaga cacccggccg gaagcactcc tgcgactgat
    33601 ccgccacctg gtggcgatcg gactgctcga ggaggacgca ccgggcgagt tcgtcccgac
    33661 cgaggtcggc gagctgctcg ccgacgacca cccagccgcg cagcgtgcct ggcacgacct
    33721 gacgcaggcc gtggcgcgcg ccgacatctc cttcacccgc ctccccgacg ccatccgtac
    33781 cggccgcccc acgtacgagt ccatctacgg caagccgttc tacgaggacc tggccggccg
    33841 ccccgacctg cgcgcgtcct tcgactcgct gctcgcctgc gaccaggacg tcgccttcga
    33901 cgctccggcc gccgcgtacg actggacgaa cgtccggcat gtgctcgacg tgggtggcgg
    33961 caagggtggt ttcgccgcgg ccatcgcgcg ccgggccccg cacgtgtcgg ccaccgtgct
    34021 ggagatggcg ggcaccgtgg acaccgcccg ctcctacctg aaggacgagg gcctctccga
    34081 ccgtgtcgac gtcgtcgagg gggacttctt cgagccgctg ccccgcaagg cggacgcgat
    34141 catcctctct ttcgtcctcc tcaactggcc ggaccacgac gccgtccgga tcctcacccg
    34201 ctgcgccgag gccctggagc ccggcgggcg catcctgatc cacgagcgcg acgacctcca
    34261 cgagaactcg ttcaacgaac agttcacaga gctcgatctg cggatgctgg tcttcctcgg
    34321 cggtgccctg cgcacccgcg agaagtggga cggcctggcc gcgtcggcgg gcctcgtggt
    34381 cgaggaggtg cggcaactgc cgtcgccgac catcccgtac gacctctcgc tcctcgtcct
    34441 tgcccccgcg gccaccggcg cctgacacac gaggtacggg aagggttcat cagcaatgcc
    34501 gacacgcatg atcaccaacg atgaggtgac cctgtggagc gaagggctcg gcgatccggc
    34561 cgacgccccg ttgctcctga tcgccggcgg caacctctcg gccaaatcgt ggccggacga
    34621 gttcgtcgaa cgcctggtcg cggccgggca cttcgtgatc cgctacgacc accgggacac
    34681 cgggcgctcc tcccggtgcg acttcgcgct ccacccctac ggcttcgacg agctggccgc
    34741 cgacgcgctg gccgtcctgg acggctggca ggtccgcgcc gcccatgtgg tgggcatgtc
    34801 gctgggcaac accatcggcc agctgctcgc cctggacgct ccggagcgtc tcctcacact
    34861 caccgtgatg ctggggggcg cgctcgacgt cgacttcgac gccgacctgg aggcggcgct
    34921 caagggtgag ccttccgtca gcggactgcc ggtgcccagc cagcggttcc tcgacatgat
    34981 gacgatgctt cagcaaccgg ccgagacgga cgaggaactg ctggagcgcc gagtggagaa
    35041 gtggcgccta ctcaacgggg agggagtgcc cttcgacgcc gacgagttcc ggcgtcgtga
    35101 actcctggcc gccgggcacg cgggaacgtt cgacgagccg atcgtgcacc acatgatccc
    35161 gctgccgccg gtgtcgcggg gggcggagtt gtcccgcgtc accacaccgg tactggcgat
    35221 ccaggcgatg tgcgaccccg cggccccgcc gccgcacgcc cggcacctcg ccaaccggat
    35281 tcccggcgcc cgggtcgtgg agatcgagaa catggggcac gccctgcccc tcgcggtcca
    35341 cgagccgctg gccgccgcca tctgcgccca cacccgggcc gcgacagtgt gaggagcacg
    35401 acgNNcccgg gccgcgacag tgtgaggagc acgacgatgc ccacacccac gtccgcgccg
    35461 ccggccgccc cgaccgacag cgagctgggg cgccatctgc tgaccgtgcg cggcttccac
    35521 ttcgtcttcg gcgcgctggg cgacccctat gcccggcgac tgcgcggcga ggccgatcat
    35581 ctgtccctcg gtgagctggt ccgcgaccgg ggcccgctcc acggcagtgc gctgggcacg
    35641 tgggtgacgg cggacggcgg aatatcggcc cgcctgctgg acgatccgct gctgggtccc
    35701 cggcaccccg cctcagaggg cccgcaggag cacgttctcg agaacgtctg ggagacctgg
    35761 cggacctgtc acgtcactcc gctcggcgag gacctgctga cgccggccgc cgccgactcc
    35821 gaccgtctcg cagccctgct cggtccggtc ctcgggcccc gtacgtgcac cgcgtggcag
    35881 gtcgacgcgg ggcgtgcggt gcaccgggtg ctggacggcc tgccgccgca cttcgacgtg
    35941 gtatcggatc tggcccggcc tgcgatcgcg ggctcgctcg ccgccgtcct gggtctcccg
    36001 gacgaggcac gggcggaact gccggacctg ctggccgcct gcggcccggt gctcgactcc
    36061 gccctctgcc cgccgcgcct cccggtggcc cgggcgatga cgcaggcgct gcgccgcgtc
    36121 cgggagctga tggcggcggc cgtggccaac cacctcaccg caccggccga cggtgcggtg
    36181 agcgccctgc tggccgtgga ccccggcggc ggacgcgatc ccggggacac cgtcacggcc
    36241 gcagtgctga gcacggtggt cggagccgag acagcgatca ccaccgtggc gaacgccgtc
    36301 atggctctgc tgaagcacga cgagcagtgg tcgctgctgc gggccgatcc cggcagggcg
    36361 gcggacgcgg tcgaggagac cctgcgctgg gcgccgcctg tgacgctgcg cagcctgatc
    36421 acccagggag aggttcagat cggtggcgag acgctggagg cggaccagca cgtggtggtg
    36481 ctggtcgacg ccgcccagcg ggacccggcg ctgtacgagg acccggaccg attccgtctc
    36541 gaccgccccc gtagccccgg tttcacgcac atggccctgg cgggccggga ccatctgggg
    36601 ctggtcgccc cgctcgtccg cgtgcagtgc accgccgtcc tgcgggcgct tgccgaacgg
    36661 ctgcccgggc tgcgggccga gggcgagccg ctgcggcgcg ggcgctcccc tgtggtccgc
    36721 gccccgctct cgctgcggct ggcccagaag tgacccaggg agggtgaccc catgaaggtg
    36781 ctcgtgacgg cgttcgccat ggacgcgcac ttcaatggtg tggtgccgct cgcctgggcg
    36841 ctgcgggcgg ccgggcacga cgtccgggtg gcgagccagc ccgctctcac cgacagcatc
    36901 acccgcgctg gactcacggc cgtaccggtg ggtacggacc accaggtgca ggcggcgatg
    36961 ggggccatgg cgcccggcgt gttcgcgctg cacctgaacc cggactacct ggagaaccgg
    37021 ccggagctgc tcgacctgga gttcctcgaa gcgtccacgt ccatgctgac ggcggcgttc
    37081 tacgcccaga tcaacaacga ctccatgatc gacgagatgg tggacttcgc cgcctggtgg
    37141 cgtcccgacc tggtcgtctg ggagcccttc actttcggcg gcgcggtggc ggcccaggtg
    37201 accggcgcgg cgcaggcccg cctgctgtgg ggcccggacc tcttcctgcg ggtgcacgac
    37261 cggttccagc aggtgctgca cgaggtgccg gccgagcgcc gggacgacgc cctggaggag
    37321 tggctgacgt ggacgctgga gcggcacggt gcggccttcg ggcccgaggt gatcagcggc
    37381 cactggacga tcgaccagat gccgccgagc gtgcggttcg ccacggcccg cccgacggtg
    37441 ccgatgcggt tcgtcccgta caacgggccg gtcccggcgg tggtgccgcc gtggctgcgg
    37501 gcggatccgg ggcgcccgag ggtcctgctc acccaaggca tcacggagcg ctcgacgggc
    37561 ttcaccgggc tgccccgggc cggtgagctg ctggcctcga tcgcggagct ggacgccgag
    37621 gtggtcgcca cggtcaaggc cgaggagcgc gagggcctgc cgcctctgcc cgggaacgtg
    37681 cgggtggtgg acagcctgtc cctgcacgtc gtcctgccga gctgcgcggc cgtcgtgcac
    37741 cacggcggcg ccggcacctg ggcgacggcg gcgctgcacg gggtgcctca gcttgccctc
    37801 gcctggcagt gggacgacgt cttccgggcc gggcagctgg agaagctggg cgcggggatc
    37861 ttcctcccgc cgcacggcga gggcgcctcg gccggccggg tcagggacag gctggctcag
    37921 gtactggccg agccgtcctt ccggcagggc gcggcgcgga tccgcgcgga gatgctgcgg
    37981 accccggcac ccggtgcggt ggtgccgacg ctggaacagc tgacggcccg gcaccgtgct
    38041 ccggccgggc agggcgtccg gcactagggg ctttcgtttg gatcagcggg cggaccgcag
    38101 gaagatgccg gcgacgtgga gtacggccag gtagagggtc gctgtcttgt cgtagcgggt
    38161 ggcgatgccg cgccactgct tgaggtggtt gatgcaccgc tcgacgatgt tgcgctgctt
    38221 gtaggtctcg cggtcgaagg ccggtggcct gccgccccgg ctgcctcgtc gcagtcgggg
    38281 ccacgctgat ctgccgggac cggaatcacc gcccggatgc cgcgcttgcg caggtggtcg
    38341 cggatcgcgc gggatgaata ggccttgtcc gccaggacta cgtccggtct ggtgcgcgga
    38401 cggccacgtc gccggggaac gcgcaggcgt gccatgacgt cggtgaaagc cggtgcatcg
    38461 ccggcctggc cggcggtgag aacgaacgcg agaggccggc agcgggcgtc ggctgcgagg
    38521 tggatcttgg tcgtcagccc accgcgggac cggccgatgg cgtggtcggc cggttcgccg
    38581 actgaggccc ctttttgcgg gccccggccg cgtgctggtg agctcgcacg atcgtggagt
    38641 ccacggacac agcccaggtc aggtcctcat cggcatcggc ctgtgccatc aacgcggtga
    38701 acacccgctc ccaggtgcca tcgacggccc acatccgcaa ccggttgtag acgccacgcc
    38761 agttgccgta cttctccggc agatggaccc actgggttcc gcgaaccatg gcgggtgtgc
    38821 acgcgtccct ctcgaaggga tccgcatgcN Ngcatgcaga cagcgggtga gtccccgccg
    38881 aaacccgcag gttcttccac cgccgccaac gccagctgcg tatcatctgc ggcccgcatg
    38941 ttcgctacat cctcgaatag aacccattga ctttcagatc aataatccgg aagtcccgtt
    39001 gttgcagaat cctgtcagca tccggcccgg ggtgacagcc tcggatgtgt acgccttccc
    39061 ggcgatctgg gcgagttgac gcagatcatc gatcccgagc tggtcgatgc agtactcgat
    39121 accccggtgc gcggggagcg tcggctgcgg ctgttgccgg cgcgcgtcgt ggtgtacttc
    39181 gtgctcgcct tcgccttctt cgagcagtcc tcctaccagg cggtacgggc caagctcacg
    39241 gccgggctcg gcgccgtgcc agtagcgcgc ccgtgcgcct cgttgctgtc gcgggcgagg
    39301 cgcagtgtgg ggagcgcacc gctgcgccgc ctgttcgcga ttctttccgg cccggtcgcc
    39361 gacgcggcca gtcccgcacc ttctaccggg gcttgcgcct cgtcgccgtg gacggcatga
    39421 cgctgcacac cgccgccgag ctcgaacagg ggtggcgcgc tcttcaacac gtgaccttcc
    39481 tcagacccag ctggatcgga gacatcgccc gcgccgccgt cgtcctcaac ggagtttgga
    39541 agtgatcacc gctgagcaaa cctcagtgtg ccggatgtgc gcctggcctg tgagggctct
    39601 ccccgccgac gcctcgggcg cgcatcggct tgcgggcgta cgtcaatcgg cgcttgagtc
    39661 ctggtcagga acgcgccgcg agctctggtg acatctctgg ccttgctcgg cggaaacaca
    39721 gctggccgtc agaccggtgc cgtcatccga cgacggggcc tcgtcgatat tgcggccggg
    39781 atctgtccgc aatcgccggt agcgtgagaa gtggccctct tccgtcaatg tgaggatgct
    39841 catgcagcag caggctattc agatcatcgg tgcccgtgag aacaacctca agggcatctc
    39901 cgtggaggtg ccgaaacaca aggtcaccgt gttcacgggg gtatcgggat cgggaaagtc
    39961 gtccttggta ttcgacacaa tcgcggcgga atcccaacgg cagctcaatg agacgttcac
    40021 cgcgttcgtg cgcaatcgcc tgcccaaata cggtcagccc gacgtggacg acatcgcgaa
    40081 cctctccgct gcggtgatca tcgatcagaa gcggatcggg gggaacgcgc ggtccaccgt
    40141 cgggacgatc accgacatct acgccttgct ccggctgctc tattcccggg tgggcaagcc
    40201 ctggattggt tattcgaacg ccttctcgtt caacgacccc tcgggaatgt gccccgattg
    40261 cgagggcctc ggccaccggg tgcaggtcga cctcgacaag ctgctcgaca ggtccaagtc
    40321 cctcaatgag ggcgccatcc ggcatcccgc cttcaatgtt ggtggctggt tctggaagct
    40381 gtacgccaat tccggcctct tcgacaacga caagaagctc cgcgactaca ccgagagcga
    40441 gtggcaggcg ttcctgtacg gggcccaggg gtcgatcgct ctggagtggc agggtggcaa
    40501 ggtcaactcg aagtacgaag ggctgatgga caagttcaac cggctctacc tgcgcaagga
    40561 gccggacgag atgagcgcca agaaccgggt ggcgctgcaa caggtcgtca cccgggggcc
    40621 ctgcgacacc tgcaaggggc aacggctcag ccagcgggcg ctcggctgcc gcatcaacgg
    40681 ccggaacatc gccgaactcg cctccctgga gatcgccgac ctgatggagg cggtcaagaa
    40741 ggtcgacacg tcctccgtct ccaccctgac ggccagtctg atcgagcggc tccagcacct
    40801 catcgaactg gggctgggat acctcagcct caaccgtgag acctccacgc tctccggcgg
    40861 cgagtcgcag cgcatcaaga tggtgcgtca cctgaacagt tcgctcgtcg acatggtgta
    40921 catcttcgac gagcccacga tcggcctgca ccccagcgac gtccagcggc tcagccggct
    40981 cctgatggaa ctggccgaga agggcaacac cgtgctggtg gtcgagcacg accgcgacat
    41041 catcgaggtg gccgagcacg tcatcgacat cgggcccggg gccgggcggc acggaggcga
    41101 gatcgtctac cagggcgacg tccggggcct caccgaggcg gacacgccga ccggacggtt
    41161 cctccgcagg atcatcccga tcaaggagcg attccgcggg cccaggggac acctggaggt
    41221 gacgggagcc cggatccaca acctcaagga catcagcgta cggattccgc tcggcgtact
    41281 gaccgccgtc accggaccgg ctggctccgg caagagcacg ctcatccacg acgtactgct
    41341 gcggcagcac ccctcggcgg tcgtcatcga ccagtccgcg gtcaccacca accggcgttc
    41401 gaacccggcg acctacaccg gcatcatgga cgagatccgc aggctgttcg cccgcgagaa
    41461 ccaggtcagc ccctcactgt tcagcttcaa ctccgagggc gcctgcccca cctgccaggg
    41521 acacggcatc atctacaccg acctcgcctt catggatccg atgatcacga cctgcgaggt
    41581 ctgcgcgggg atgcgtttca ccgatgacgt cctgcgcctg accctgcgcg ggcagaacat
    41641 ccacgacgtg ctgtcgatga gcgccgctga ggcggccgag ttcttcaccg aacccaaggt
    41701 tgccaagacc ctccgttcca tcaaccaggt cggcctcggc tatctccagc tcgggcagcc
    41761 gctcaacacc ctctccggcg gcgagtgcca gcgcatcaag ctcgccacgg agcttgggaa
    41821 gaagggcagc gtctacgtca tggacgagcc caccaccgga ctccacatgt ccgacgtcga
    41881 cagcctcgta cacctggtcg acggcctcgt cgagaagggg gactcggtca tcgtcatcga
    41941 gcacaatctc gacgtcgtca agcatgcgga ctgggtcgtc gacctcggcc ccgggggcgg
    42001 cagcgagggc ggccgggtga tctttgaggg cacccccgct gacctggcgg aggccgagca
    42061 ctccgtcact gggcggttcc tcgccgcgtc cctggcgggc gccggttccg aggccgacca
    42121 ccgggcccgg cgctgatcct tgaccccggg tgctaagcgg cgtcccgtac gagcgcgtcc
    42181 ggccgggaac gccgcggccc cggccggacc ctgagagcgg catgc
//
