LOCUS       Fredericamycin            33064 bp	DNA     linear     02-Oct-2012
DEFINITION  Fredericamycin biosynthesis cluster
ACCESSION   Fredericamycin
VERSION
KEYWORDS
SOURCE      Streptomyces griseus
FEATURES             Location/Qualifiers
     source          1..33064
                     /organism="Streptomyces griseus"
                     /mol_type="genomic DNA"
                     /strain_name=""
                     /db_xref="taxon:1911"
     CDS             complement(33..1631)
                     /locus_tag="Fred_00010"
                     /product="putative acyl-CoA carboxylase beta subunit"
                     /note="original product:putative acyl CoA decarboxylase"
                     /note="category:5.1 general function"
                     /transl_table=11
                     /inferenece="InterPro:IPR011763"
                     /inferenece="InterPro:IPR011762"
                     /inferenece="InterPro:IPR000022"
                     /translation="MSVVEESPLNSAAPADGHLRDRAAELAALHERVRRGPGERATEA
                     QHAKGKLTVRERLALLFDEGTFTEIEELRRHRATGFGLEQRRPHTDGVVTGWGEVDGR
                     TVFAYAHDFRIFGGALGEAHAEKIHKLLDLAESAGRPVVGLCDGAGARIQEGVTALAG
                     YGGIFARNVRNSGVIPQISVILGPCAGGAAYSPALTDFVFMVRGTSQMFITGPDVVQA
                     VTGEVITHDALGGADAHASVSGVAHAAYDDEESCLADVRHLLSLLPSNNRELPPAAPG
                     ADPASRRTEALLDLVPADPGRAYDMRAVITEIVDDGEVFEIQESWATNIVCVIARLDG
                     QAVGIVANQPAAFAGVLDIHASEKAARFVQTCDAFNLPLVTLVDVPGFLPGVDQEHGG
                     IIRHGAKLLYAYCNATVPRVQLILRKAYGGAYIVMDSRSIGADVSLAWPGNEIAVMGA
                     EGAAGVVFRREIAAADDPEATRARLVKEYRAELMHPYYAAERGLVDSVIDPAETRSRL
                     IGALTMLRAKHAPLPTRKHGNQPQ"
     CDS             1727..2770
                     /locus_tag="Fred_00020"
                     /product="putative acyltransferase"
                     /note="original product:putative acyl transferase"
                     /gene="Orf2"
                     /note="category:1.4 Other"
                     /EC_number="2.3.1.-"
                     /transl_table=11
                     /inferenece="InterPro:IPR016035"
                     /inferenece="InterPro:IPR014043"
                     /inferenece="InterPro:IPR001227"
                     /inferenece="InterPro:IPR016036"
                     /translation="MTRPTQRSVVLMFPGTGAQHPRMAAGLYRREPVFTAAVDAVLGE
                     LGAEGEAVRADWLADVPAVPLEADARSAPLLFAVDYAVGRLVESWGVRPAAYVGHSMG
                     EFAAATLAGVFRLEDAVRLLWDRVEKQRATPVGGMTAVAAARHEVAGYLGAGVVVGAV
                     NGPRHTVLSGPEAPLRAVEERLASDGRTFRRLATRTPYHSPALAPLVPGGAALVAGMP
                     LSAPRTLLYSAYTAGPLREREALAPAFWAAQPTAPVLFWQTLDRVLRDDDRLLVEAGP
                     SHSLSVLARSHPAVRSGRSTVATTLPPRAQGPRADRLSLRALRAWLSAEGALPVPPGP
                     GHSGTLPVELPLS"
     CDS             complement(2731..4920)
                     /locus_tag="Fred_00030"
                     /note="original product:putative multicopper oxidase"
                     /note="category:5.1 general function"
                     /transl_table=11
                     /inferenece="InterPro:IPR011707"
                     /inferenece="InterPro:IPR002355"
                     /inferenece="InterPro:IPR008972"
                     /inferenece="InterPro:IPR011706"
                     /inferenece="InterPro:IPR001117"
                     /translation="MVENLFEQNILWAVLTAVVWGCAARGARRLAIRPAAALRRRARL
                     GLALLTVALLTLAVRAGLALGLVATAGWLGGADYVLFGALPPVLAAVAVAALAVPAYL
                     RVLRAAPAAGSDPDGSPLPPGLRALAAGDRLVVPVQACCATTLLGAAGTLHPPAPPYT
                     GPFLVHILLGGAVCGGLLLLHRRRRAALEARGGRPVPRARQLVRATATVTGLAVLTAG
                     GCTLAAGQSRLPDRTSASAHAHSGTAPTRSVVDLTGDRSGEPDRRFTLTATDRTLRLA
                     SGEKVAALSFNNSLPGPELRVRRGQLVEVVLVNRDVADGVTLHWHGVDVPNAEDGVAG
                     VTQDAVPPGGHHVYRFRPDRAGTFWYHSHQQSSIAVARGLFGALVVEEPSKDQRAPFD
                     RTVVAHAWPVGTARNSPGGPHGGGALSGTNGLGGTLRTAFGDDTRTRAEKVRAGTEVR
                     LRLVNADNCPRTYSLAGTSFAVAAIDGTEVQGASEVRGRLLRVAGGGRYDLTYRQPDG
                     PVRLTVVGDANASADGQGFEGCGQDGAYGTGRTETASLQLAPNPSAAGRVPAVSGPLF
                     DPLHYGSAAGAGPLGRSPRFDRDFSLVLGNSLGFHDGSPMVLWTVNNAVHPDIPALVV
                     EEGDLVRTTFLNRSLDDHPMHLHGHRMLVLSRDGEPATGSPWWTDTLNVAPGERYEVA
                     FRSDNPGLWMDHCHNLDHARDGMVLHLAYDGVTGPYESGSSTGNVPE"
     CDS             4971..5771
                     /locus_tag="Fred_00040"
                     /product="putative ketoreductase"
                     /note="original product:putative 3-ketoacyl-ACP reductase"
                     /gene="fdmC"
                     /note="category:3.3 modification reduction"
                     /transl_table=11
                     /inferenece="InterPro:IPR002198"
                     /inferenece="InterPro:IPR020904"
                     /inferenece="InterPro:IPR002347"
                     /inferenece="InterPro:IPR016040"
                     /translation="MLTPGRSGSPGRVGHGREHAMELRRSALVTGGSRGIGRAVAVRL
                     AQDGYDIGFCSRSADEAALETARLVTSAGARAHHVVCDVTDADAVRTFVAEAEEKLGP
                     AYAVVNSAGVLRDRPMALMAARDWQDVVGTSLDGAFHVCRAVVRGLLTRRAGALVNVS
                     SVIGVYGNAGQTNYAAAKGGLNGLTRALAKEVAPYGVRVNAVAPGFIETEMLDGMTAK
                     AREAALGKIAMARFGSAESVAALVAFLVSDAADYITGQVVQIDGGIAL"
     CDS             5782..7263
                     /locus_tag="Fred_00050"
                     /note="original product:putative peptide transporter"
                     /gene="fdmT"
                     /note="category:4.3 transport"
                     /transl_table=11
                     /inferenece="InterPro:IPR005279"
                     /inferenece="InterPro:IPR000109"
                     /inferenece="InterPro:IPR016196"
                     /translation="MTLDEGTSADSVTRTDPERPLRSMFRERWFSTLFMTDMWERFSF
                     YGMQALLFLYATAPVAEDGLGLTAGTAGALFGLYVSGSFLAAMPGGWLGDRVLGTHRA
                     MLCGALVIMAGHLSMAVPAQATFYLGLVLVACGTGLLKPNLPVMFDQMNPGASSSRRQ
                     AAFSLFYMSIQVSALVGPLVTGILGERVNWHLGFGAAAVGMAFGVLQYLHGAPSLRGA
                     ATGPSRPLPPAALRRLVRRCWAALAGAVLLGAGLALSGGLPLRPVLALCGLASLVAPV
                     WYFRRLLRDRSLGEAERARVRGYVRVFVPSVLFWAMFGQVGSVFSLFAREHTDREVAG
                     FSVPASWFQSAHPLFLLLLAPVFAWLWLRIGARAGVARKFSVGLLCAGGGFAFLAVGA
                     WLASGGRAVVSPLWLLAAFLCMTCGELVFGPVGLSTTAESTPAGHGSRMMGLFYLGAA
                     LGAGVGGQLSHLVGVVPLWSYLAGFVVAAVATALLLPRRTAEI"
     CDS             7420..7740
                     /locus_tag="Fred_00060"
                     /product="putative cyclase"
                     /note="original product:putative polyketide cyclase"
                     /gene="fdmD"
                     /note="category:3.4 other modification"
                     /transl_table=11
                     /inferenece="InterPro:IPR011008"
                     /inferenece="InterPro:IPR006765"
                     /translation="MAHRTLIVARMDHDDADKVAALFAESDATELPHMIGVQRRTLFR
                     FQGLYFHLVEAEAPINGDLYQARSHPLYQDINTRLQEFMTPYSPSWREPKDSMAEPFY
                     SWTP"
     CDS             7804..8229
                     /locus_tag="Fred_00070"
                     /note="original product:putative polyketide cyclase"
                     /gene="fdmE"
                     /transl_table=11
                     /inferenece="InterPro:IPR014710"
                     /inferenece="InterPro:IPR013096"
                     /inferenece="InterPro:IPR016672"
                     /inferenece="InterPro:IPR011051"
                     /translation="MQTSDLIKVAVDDVEPNRARGGDLRVLLSPKTCGATSGFMGVGA
                     LEPGEFVSEHYHPYSEEFFHAVEGRVLLRVDGRELVLEPGESFMVPIGVRHRIENPGS
                     GTARVAFFLSPLAPRPELGHVDCEPLPGEGAPPEVGGAR"
     CDS             8226..9491
                     /locus_tag="Fred_00080"
                     /product="putative polyketide synthase beta-ketoacyl
                     synthase subunit"
                     /note="original product:3-ketoacyl-ACP synthase"
                     /gene="fdmF"
                     /note="category:1.1 PKS"
                     /transl_table=11
                     /inferenece="InterPro:IPR014030"
                     /inferenece="InterPro:IPR016038"
                     /inferenece="InterPro:IPR016039"
                     /inferenece="InterPro:IPR014031"
                     /translation="MTARAVITGIGVVAPGRPGRENFWEMIVKGQTATRRITLFDPAP
                     FRSRIGAECDFDPERNGLSYQEMARTDRAGQFAIVAAREAVADSGMDLGAENAHRVGV
                     SVGNGVGNAISMEQAYRTVSDNGRRWLVDQEYAGPHLYSSVMSSSLAAEVAWATGAEG
                     PATVVSSGCCAGIDAVGYAVDLIREGSAEVMVAGATDAPIYPITVSCFDTLRASSTSN
                     DDPEHACRPFDRRRNGLVLGEGSAVFVVEELEHARRRGARIYCEVAGYSARANGYHMT
                     GLRPDGREMGEAITAALDEARINPDEVDYANAHGSGTKQNDRHETAAYKRSLGEHAYR
                     IPVSSIKSMVGHSLGSIGSIEIAASALAIDRGTVPPTANYEERDPECDLDYVPGTARE
                     AELDVVLSVGSGFGGFQSAVVLTSPRRIA"
     CDS             9488..10699
                     /locus_tag="Fred_00090"
                     /product="putative polyketide synthase chain length factor
                     subunit"
                     /note="original product:chain length factor"
                     /gene="fdmG"
                     /note="category:1.1 PKS"
                     /transl_table=11
                     /inferenece="InterPro:IPR014031"
                     /inferenece="InterPro:IPR016039"
                     /inferenece="InterPro:IPR014030"
                     /inferenece="InterPro:IPR016038"
                     /translation="MTGPVITGVGVVAPNGLDREAWWQATLDGKSGLGRISRFDPSPY
                     PAQVAGEATGFVPADHAPRRLVSETDAMTQYAFAATNEALADAGVDPAALNDLDMAVI
                     TANSSGGVEFGQRELEKLYAEGPQAVGAYMSIAWFYAATTGQLSIRHGMRGPCGVLCS
                     EQAGGLDVLAQARRVLAKGTRLVVSGGTDASLSPYGLVCQLANGRLSDESRPERAYLP
                     FDPRARGYVPGEGGAILTVESLDDARARGAGRIYGQVAGYAATFDPRPGSGRPPGLRR
                     AAELALADAGTGPEGVDVVFADGAGLPEPDRQEAEALTGLFGRGGVPVSVPKTMTGRL
                     YAGGAPLDVAAAVLALRDQVVPPSVNVRPDPVHGLDLVTDRPREARLRTALVLARGYG
                     GFNAAVVLRSV"
     CDS             10764..11018
                     /locus_tag="Fred_00100"
                     /product="polyketide synthase acyl carrier protein
                     subunit"
                     /note="original product:ACP"
                     /gene="fdmH"
                     /note="category:1.1 PKS"
                     /transl_table=11
                     /inferenece="InterPro:IPR006163"
                     /inferenece="InterPro:IPR009081"
                     /inferenece="InterPro:IPR006162"
                     /translation="MSTISFNDLKTIMSRSLGEVDGTELTEADLTTPFTEIGYDSLAV
                     LEIASQLQREYGLQIPDEAIEEMDTPQAVIDYVNTSLAGV"
     CDS             11020..11487
                     /locus_tag="Fred_00110"
                     /product="putative cyclase"
                     /note="original product:putative polyketide cyclase"
                     /gene="fdmI"
                     /note="category:3.4 other modification"
                     /transl_table=11
                     /inferenece="InterPro:IPR019587"
                     /translation="MAASTDNSVVVDAPMELLWDMTNDIESWPGLFSEYAKAEILGRD
                     GATVTFRLTLHPDESGAVWDWVSERTPDPATRTVRARRIETGPFVHMNILWTYASTDA
                     GVEMRWRQEFEVKPGLPFGDAEMTERLNTNTRREMARIKELVEKAAAERRAAR"
     CDS             11484..11807
                     /locus_tag="Fred_00120"
                     /product="hypothetical protein"
                     /note="original product:putative monooxygenase"
                     /gene="fdmJ"
                     /note="category:5.3 hypothetical protein"
                     /transl_table=11
                     /inferenece="InterPro:IPR011008"
                     /inferenece="InterPro:IPR007138"
                     /translation="MRPGLRVLLRIRVAEGQEERFEELWRAHAETVRSFTDNHGQQLL
                     RTRGERGSYTVLTDWTDEPSFRAFERSPEQQAYLRELWAIRSGGEMQLLDLVHTLSPA
                     TPAEA"
     CDS             11825..12259
                     /locus_tag="Fred_00130"
                     /product="hypothetical protein"
                     /note="original product:putative oxygenase"
                     /gene="fdmK"
                     /note="category:5.3 hypothetical protein"
                     /transl_table=11
                     /inferenece="InterPro:IPR003033"
                     /translation="MSVQQEQVTELIDLVQSVPAKEVEGVVATRPGGVDGALTLIFDL
                     LVSEFNPAKAEGEKGVFQFDIACADGRKHHHVEVVDGTCRTGQGVHDHPDITIGIKFP
                     DMLAMGVGKLPGAKAFLTGKLKLRGSPLMGTKLGEWFDHPET"
     CDS             complement(12333..13073)
                     /locus_tag="Fred_00140"
                     /product="hypothetical protein"
                     /note="original product:putative monooxygenase"
                     /gene="fdmL"
                     /note="category:5.3 hypothetical protein"
                     /transl_table=11
                     /inferenece="InterPro:IPR007575"
                     /translation="MPLDAVTYRVAPGHEEELTEVFSPHNFTRVDSPVIKNGTGETVG
                     MLLGTGLFVQEDVMVRVIHHDGVGAARIAHHMSVQKGVHDAERAILPYLAEPRDTETP
                     EGFREHFHRSLMTVLEQHSPDERPAAGTVALRYPLRAGAGAELAAARATANVRAFLRL
                     AEEYPAIVRTALFLHEDTLVRVVQYDGHPYDVVSYLADRCFGQDAESWLVPYLRAPER
                     HPDRDAYLARVHEQAMFSLAHMSVLGVG"
     CDS             complement(13111..13560)
                     /locus_tag="Fred_00150"
                     /product="C-6 hydroxylase"
                     /note="original product:putative monooxygenase"
                     /gene="fdmM"
                     /note="category:3.1 modification hydroxylation"
                     /transl_table=11
                     /inferenece="InterPro:IPR013901"
                     /translation="MMLEEVLSGVVLAGTGTVTGVFVAVAVSVGPAMSAMGRAEYLRA
                     HALLGKGYHPLMPILVNIVTLSGFALAFLAGAPGNVLFPLASVLLIGVQAVSHLGNVP
                     INRSLSGLAAAGSWVDPRPQWRAWHRLRTVLAALALAAVTVAVLTAR"
     CDS             13801..14265
                     /locus_tag="Fred_00160"
                     /product="C-8 hydroxylase"
                     /note="original product:putative monooxygenase"
                     /gene="fdmM1"
                     /note="category:3.1 modification hydroxylation"
                     /transl_table=11
                     /inferenece="InterPro:IPR013901"
                     /translation="MAWEQVLMPPALLAGGLAAGGLAISVLAAPLFTTLPTVMYVPVH
                     QGLVTRFDPFMPVSLASCLFCDAALVLAAQGGAVRLLAAAAALLLACAMTVSLTKNVP
                     INRWLATLDPRALPADFQRRDPRTRWIRWNRVRGALAVAALVANVAAAALLI"
     CDS             14322..15383
                     /locus_tag="Fred_00170"
                     /product="putative O-methyltransferase"
                     /note="original product:putative o-methyltransferase"
                     /gene="fdmN"
                     /note="category:3.2 modification methylation"
                     /EC_number="2.1.1.-"
                     /transl_table=11
                     /inferenece="InterPro:IPR001077"
                     /inferenece="InterPro:IPR016461"
                     /translation="MDTMTGVVGPALTASLPPHVRLLLLTDGKRISRVLHVLAELAVA
                     DELADGPLTVAELAVRTDAHPDSLGRVLRVAAAFGVFEEREDGRYALTELSEVLRSDV
                     PGSQRDMVLYNGTEMLWRSYGSLLHTVRTGRPAFEAVYQQDFFTHLEENPQAGALFDR
                     AMTGMSRATARMLLDSYDFGRFLRLADVGGGRGLFLAEVLTRHPGSRGTLIDRPAVTG
                     EAAGLLREAGVADRVEVVPGDFFEELPKGHDAYVLKAVLHDWDDRRAAAILGRVRDAL
                     AGRPDGRLLICEFLVGPANQWDRGKLLDLDMLVRFGGRERDADQWRALLAATGFELVN
                     DPVPGRWAVLECRPVPADG"
     CDS             15497..16246
                     /locus_tag="Fred_00180"
                     /product="putative C-19 ketoreductase"
                     /note="original product:putative 3-ketoacyl-ACP reductase"
                     /gene="fdmO"
                     /note="category:3.3 modification reduction"
                     /transl_table=11
                     /inferenece="InterPro:IPR016040"
                     /inferenece="InterPro:IPR020904"
                     /inferenece="InterPro:IPR002347"
                     /inferenece="InterPro:IPR002198"
                     /translation="MELRLVGTNALVTGGTRGIGRAIVLALAKAGATVVTCYRTEGEA
                     ADSLARELKELGGDHALVRADVGTTEGVEAVLAACRTRFETLDVLVNNAGIISQVPFA
                     QLPFEEWERVVTTNLTGPFMVISKALPLLRKGSSVINIGSRGAMAGIPLRGHYTASKA
                     GLVGLTRSLCKELGGKGIRFNVVAPGVIDTSEPEELTEEQRAAYDERYLRMMALGRFG
                     RPDEIAGAVLFLASDLSTYVNGETLHVDGGV"
     CDS             16248..16559
                     /locus_tag="Fred_00190"
                     /product="hypothetical protein"
                     /note="original product:putative monooxygenase"
                     /gene="fdmP"
                     /note="category:5.3 hypothetical protein"
                     /transl_table=11
                     /inferenece="InterPro:IPR011008"
                     /inferenece="InterPro:IPR007138"
                     /translation="MAAERVGSFRVLLTVQVKPGLEAEFEKVWAEGSKEVTSQSANLG
                     HSLARSAREESVYYVTSDWTDKESFLAFESSPGHVAHREKLHPYRTGGALAMMHLVGV
                     A"
     CDS             16559..16876
                     /locus_tag="Fred_00200"
                     /product="hypothetical protein"
                     /note="original product:putative monooxygenase"
                     /gene="fdmQ"
                     /note="category:5.3 hypothetical protein"
                     /transl_table=11
                     /inferenece="InterPro:IPR007138"
                     /inferenece="InterPro:IPR011008"
                     /translation="MDGTTSRVRVMLYLRASEDQAPAVAEAYHRISADLAGTPGLLGN
                     ELLREVSDPGAFAVLSDWESLPAFQAWESGSAHRGTTSPLREYQDSARARPFALFEVA
                     ATY"
     CDS             complement(17040..18041)
                     /locus_tag="Fred_00210"
                     /product="putative 3-oxoacyl-[acyl-carrier-protein]
                     synthase III"
                     /note="original product:putative 3-keto-acyl-ACP synthase"
                     /note="product synonym:putative beta-ketoacyl-acyl carrier
                     protein synthase III"
                     /gene="fdmS"
                     /note="category:5.1 general function"
                     /transl_table=11
                     /inferenece="InterPro:IPR016038"
                     /inferenece="InterPro:IPR013747"
                     /inferenece="InterPro:IPR004655"
                     /inferenece="InterPro:IPR016039"
                     /inferenece="InterPro:IPR013751"
                     /translation="MTAIRDTEVLRHSRLLGVGVHRPERSVPNTEIAGRTGLDPDWIE
                     RRSGIRSRRYAGPEETLPAMATAAAEKALAAAGVSADRIDTVIVATITSMEQMPAVAV
                     EVARRLGADRAAAFDVSAACAGFCHALALAGDQVRMGRADHVLVIGAERMTDILDHED
                     GDTAFLFADGAGAVVVGPSHEPGIGPVVWRADGTRNAALRMTAPWHDGTGLRPEARPA
                     ITMSGWKVFRWATNELVPAARKMLDLAGVTVDDLDAFIPHQANMLITDHVVDQLGLPA
                     HTAVARDIVTSGNSSAASIPLAMEELLAGGKAPSGGLALLIGFGAGLVYAGQVVRLP"
     CDS             complement(18122..19153)
                     /locus_tag="Fred_00220"
                     /product="hypothetical protein"
                     /note="original product:putative membrane transporter"
                     /gene="fdmT1"
                     /note="category:5.3 hypothetical protein"
                     /transl_table=11
     CDS             complement(19310..19741)
                     /locus_tag="Fred_00230"
                     /product="putative transcriptional regulator"
                     /note="original product:transcriptional regulator"
                     /gene="fdmR"
                     /note="category:4.1 transcriptional regulator"
                     /transl_table=11
                     /inferenece="InterPro:IPR000835"
                     /inferenece="InterPro:IPR011991"
                     /translation="MIRIRRRQSRRSLARPVMKGLADPIDLNTLAVVDAVDEGGGQSG
                     RDVTVGFIADRLAIDPSRASRIVADAVRSGFIRRVASQEDGRRSCLELTPTGEEAVSA
                     AHRTRQDFYGKVLGDWDEGEQREFARLLTKFVHSLDEADHG"
     CDS             19943..20368
                     /locus_tag="Fred_00240"
                     /product="hypothetical protein"
                     /note="original product:unknown"
                     /gene="fdmU"
                     /note="category:5.3 hypothetical protein"
                     /transl_table=11
     CDS             20468..22336
                     /locus_tag="Fred_00250"
                     /product="amide synthetase"
                     /note="original product:asparagine synthetase"
                     /gene="fdmV"
                     /note="category:3.4 other modification"
                     /transl_table=11
                     /inferenece="InterPro:IPR017932"
                     /inferenece="InterPro:IPR014729"
                     /inferenece="InterPro:IPR006426"
                     /inferenece="InterPro:IPR001962"
                     /translation="MCGIAGWVVRQDGRPREDPAVAEAMAGAMACRGPDEQGVRGGRH
                     VTLVHTRMAVIDLLGGRQPMAADESEDPAATLTYCGEIYNAAELRSDLAGRGHRFRTR
                     SDTEVVLRAYLEWGERCPERLEGMFAFAVWDARTRSLFLARDRFGVKPLYYAETGDGL
                     VFGSEPKALLVHSDVSPEVDLDGLRVLFSMARAPGECVYRSLSDLPPAHTLRFGPDGR
                     LSLRRYWQLEARPHEEDLAGTVATVRGLLESSVARELVSDVPLSVLLSGGLDSSTVAA
                     LAARALADGDGGPVRTTTVTYSGYGDNFQPDLVRSAPDSPYARAVAEHIGAEHLEIEL
                     TTADLIDPVARRTVLRAQDVPAPFGDMDTSTYQAFAGVRRHSRVALTGESADEIFGGY
                     SWVHIPDLAHEEQFPWVAFEQWHPGTRRGLGQGLLSPAFKDRLDMGSYYAERYAQAMS
                     RIPRLPREGEEERRAREICDLHLTHWLPRLLERNDRLSMVSGLEVRVPFCDHRLVQYA
                     YNIPWAMKTFDGREKSVLRAAARDLLPERVLDRPKAPFPVSQDATYTKALHQELTEVL
                     ADPASPVLPLLDLEAARAVVAREGGADLQDWLHRMNVEMVLQVDAWLRELGGDVEL"
     CDS             complement(22401..24236)
                     /locus_tag="Fred_00260"
                     /product="transcriptional activator"
                     /note="original product:regulatory protein"
                     /gene="fdmR1"
                     /note="category:4.1 transcriptional regulator"
                     /transl_table=11
                     /inferenece="InterPro:IPR005158"
                     /inferenece="InterPro:IPR001867"
                     /translation="MLQIGLLGTLQVVHEGVHVTPSAPKVRQVLALLALRANATVPLH
                     QLVEELWEEHPPSSAATTLQTYIYQLRKLPGLCDQHRPGPAEDGGAALRTTPGGYRLA
                     VSPDCMDAQRFGELAARGRVFMEKGSTAEAADLMQRALAVWRGPALSDVAPGPVTGID
                     ALRLEEQRYEVLEERLDADLLLGRHHRLVSELTGLAADNPTREGLHAKLMLSLYRAGR
                     RPEALEVFQRIRRVLARELGLEPCAELQRLHQQVLAGDRGLDLPGGRTTVHAPRPGAS
                     PMTLPADSPLVGRDADLRHVGRVLSAEEGAGGPQCVAVAGPPGAGTTAFTVHLAHRLG
                     DSFPDGRLYASFGKGAAPLPVEEVLAGLLEAVGHQRSELPPHRAGRARMFRNWTEGRR
                     VLLVVDDVATTEQVADLLPAGSGSAALVAGYRRLYGSQFKARVDLPPLGHERSLELFL
                     DALGRGRGLDDPRGLHTMLDLCGDLPGPTLEAVGVLALRPHWSVRQLMDWLGRGRLSA
                     VAQQRPHPFHHVVGRCARLEPRLREALAKLAWEAADDLTVEQAAAVLGKDGDETEEML
                     EELVELFLLGVGMASDPTTERFFQYRLAPLVRTALRAMQPAPSCV"
     CDS             24472..26067
                     /locus_tag="Fred_00270"
                     /product="putative drug resistance transporter"
                     /note="original product:putative membrane transporter"
                     /gene="fdmT2"
                     /note="category:4.3 transport"
                     /transl_table=11
                     /inferenece="InterPro:IPR004638"
                     /inferenece="InterPro:IPR011701"
                     /inferenece="InterPro:IPR016196"
                     /translation="MPDAMPDRPRRPDADAPPPDGPLPPRFPLLLAALLLTSAMSMLD
                     QSIVATAGPSLTGDLGALHLYSWTFTAYMLTFSVAMPVYGKLGDLFGRRPVYLAAIVI
                     FLVGSLACGAAGSMGQLIFFRALQGLGGGGLQVSAFAVLGDLMPPRRRAKYQGWFAGV
                     MVIANLAGPLTGGLLTDQLGWRWIFYVNLPVGLLAMAGIWALLPRSTRGAARPRVDVL
                     GTALLTGLIVCLVLVTDLSGRYGWAHPAVLGTGAGAVLLAAVWTRQSRRAAEPIVPLG
                     LFANRTFTICVVVAFAVSFAFFGCVNFVPLFFQTVEGVSATRTGLLFLPAMIGMAVAT
                     VVAGQVIGRTGRYKWFPVASTALAALAAGLMSLTSADTGAVAVSALLALMGVGVGLSS
                     QVTTLVAQSSAPRRHIGVSTSTVGLARNLGVAFGATVFGSLLNARLAVGSARLLPADV
                     AERVVGGTLEPGRIGELGPRTASAVADVYSEALSTVFLSAVPVLLIGLVLALMLKDVK
                     LEARGQGGPGGQGAERPAAPRRG"
     CDS             26150..26629
                     /locus_tag="Fred_00280"
                     /product="holo-[acyl-carrier-protein] synthase"
                     /note="original product:holo-ACP synthase"
                     /note="product synonym:4'-phosphopantetheinyl transferase
                     AcpS"
                     /gene="fdmW"
                     /note="category:1.4 Other"
                     /EC_number="2.7.8.7"
                     /transl_table=11
                     /inferenece="InterPro:IPR008278"
                     /inferenece="InterPro:IPR004568"
                     /translation="MQPDDEGAREWRRGPGGSGRFPWPLRLRARHPRPAPPRIVGVGI
                     DVAAIARFGLALERSPGLRDRLFTPEEQMLPSGSPRTTASLAARFAAKEAVAKVLGAP
                     GGLRWHDVGVRTGARGRPVLQVCGTVAAAAARQGISVWHLSLTHDGDVASAVVVGAA"
     CDS             26869..27381
                     /locus_tag="Fred_00290"
                     /product="putative transcriptional regulator"
                     /note="original product:transcriptional regulator"
                     /gene="fdmR2"
                     /note="category:4.1 transcriptional regulator"
                     /transl_table=11
                     /inferenece="InterPro:IPR011991"
                     /inferenece="InterPro:IPR000835"
                     /translation="MERTTHTAGGDTAARKASPALPSGSLAQDLALVLPALHRALDRR
                     VDADFPHPKPAEGQIALMRLIRDREGVTVREAAEVLLVKPNNLSATVTQMVAAGLVER
                     RRDPDDKRVTHLHLTPTAAERTHAVDELIGGYVEQALAGLSDGERGALGAAVGALHLL
                     ERGLHPSSAS"
     CDS             27689..28906
                     /locus_tag="Fred_00300"
                     /product="putative transposase"
                     /note="original product:transposase"
                     /gene="fdmX"
                     /note="category:5.1 general function"
                     /transl_table=11
                     /inferenece="InterPro:IPR002525"
                     /inferenece="InterPro:IPR003346"
                     /translation="MFEIEDVGVFLGLDVGKTAHHGHGLTPAGKKIFDKPLPNSEPKL
                     RAVFDKLTEKFGTVLVIVDQPASIGALPLTVARDAGCRVAYLPGLAMRRIADLYPGEA
                     KTDAKDAAVIADAARTMPHTLRCLELTDEITAELTVLTGFDQDLAAEATRTSNRIRGL
                     LTQFHPSLERVLGPRLDHQAVTWLLERHGSPAALRKAGRRRLVELIRPKAPRMAQRLI
                     DDVFDALDEQTVVVPGTGTLDTVVPSLAASLASVHTQRRAMEAQINTLLEAHPLSPVL
                     TSMPGVGVRTAAVLLVTVGDGTSFPTAAHLASYAGLAPTTKSSGTSIHGEHAPRGGNR
                     QLKRAMFLSAFACMNADPASRTYYDRQRARGKTHTQALLRLARQRISVLFAMLRDGTF
                     YEPRTPKNVELAA"
     CDS             28988..30565
                     /locus_tag="Fred_00310"
                     /product="putative drug resistance transporter"
                     /note="original product:putative membrane transporter"
                     /gene="fdmT3"
                     /note="category:4.3 transport"
                     /transl_table=11
                     /inferenece="InterPro:IPR004638"
                     /inferenece="InterPro:IPR011701"
                     /inferenece="InterPro:IPR016196"
                     /translation="MSTRTPEAPPEPAPAPPSSTRRGNPWLTLIAVAFGLFMVALDGS
                     VVSMANPEIGRDLNAGTADLQWVTNSYLLALAAALILGGKLGDRFGRRTYYLIGVAGF
                     TLASVAIGLAGSIEGVIAFRAVQGFFGALLMPNTLGLLRAVFPPKKFGMAVGIWAMVS
                     SVSTALGPIVGGLLVEHVNWESVFFINAPVGVLALAFSAWVLPQAKGEEGRGTRFDIP
                     GVVLLALGLLLVVFAVVKGETWGWASPATVLTLLAGLAVLVAFGLYENRVAHPLLPMR
                     LFRNPALTVGTVITAVNFFVLLGVIFFVMLYLQNVRGYSPVESGVRTLPLSLASVVAA
                     PLGAALTGRFGARLTMPLGMLLQAGASLGILGWGLDTAYAVLWPPFVALGLGIGMVMA
                     ASSDAIVGNAPVRDAGVAGGLQSTALQVGGALGTSVLISLISSRVSATFGPELASAGV
                     PAPVADGLAEAKDAVAMGVAPVGPRLPESLHGPVTEAAGQAFLNGVHAAAWVTACLCV
                     AGAVASGWVLRRPTSGA"
     CDS             complement(30621..31229)
                     /locus_tag="Fred_00320"
                     /product="hypothetical protein"
                     /note="original product:unknown"
                     /note="category:5.3 hypothetical protein"
                     /transl_table=11
     CDS             complement(31226..32515)
                     /locus_tag="Fred_00330"
                     /product="hypothetical protein"
                     /note="original product:unknown"
                     /note="category:5.3 hypothetical protein"
                     /transl_table=11
ORIGIN      
        1 ggtaccgggc ccggtggagg ccttgggggc gttcactggg gctggttccc gtgcttgcgg
       61 gtggggagcg gggcgtgctt ggcccggagc atggtcagcg ccccgatgag gcggctccgg
      121 gtctccgccg gatcgatcac gctgtcgacg aggccgcgct cggccgcgta gtaaggatgc
      181 atcagctcgg cccggtactc cttgaccaga cgggcccgcg tcgcctcggg gtcgtcggcc
      241 gcggcgatct cccggcggaa gaccacgccg gccgctccct ccgcccccat caccgcgatc
      301 tcgttgcccg gccaggccag cgagacgtcc gctccgatgg agcgggagtc catcacgatg
      361 tacgcgccgc cgtaggcctt gcgcaggatg agctgcaccc ggggaacggt cgcgttgcag
      421 tacgcgtaga gcagtttcgc gccgtgccgg atgatgccgc cgtgttcctg gtcgacgccg
      481 ggcaggaagc cgggcacgtc gaccagggtc accaggggca ggttgaaggc gtcgcaggtc
      541 tggacgaagc gtgcggcctt ctcggacgcg tggatgtcga ggaccccggc gaaggcggcg
      601 ggctggttgg cgacgatgcc gacggcctgt ccgtcgagcc gggcgatgac acagacgatg
      661 ttggtggccc aggactcctg gatctcgaag acctcaccgt cgtcgacgat ctccgtgatc
      721 accgcgcgca tgtcgtaggc ccggcccgga tcggccggca ccaggtccag cagcgcctcg
      781 gtccggcggc tcgccgggtc cgcgccgggc gcggcgggcg gtagttcccg gttgttcgag
      841 ggcagcaggg agagcaggtg gcggacgtcc gccaggcagc tctcctcatc gtcgtaggcg
      901 gcgtgggcga cacccgagac ggacgcgtgg gcgtcggcgc ccccgagcgc gtcgtgggtg
      961 atgacctcgc cggtgacggc ctgcaccacg tccgggccgg tgatgaacat ctgggaggtg
     1021 ccgcgcacca tgaagacgaa gtccgtcagc gccggggagt aggcggcgcc gcccgcgcac
     1081 ggcccgagga tcacgctgat ctgcgggatg accccggagt tgcgcacgtt ccgggcgaag
     1141 atgccgccgt agccggcgag ggccgtcacg ccctcctgaa tgcgggcacc cgcgccgtcg
     1201 cagaggccga ccaccgggcg gccggcggac tcggcgaggt ccagcagttt gtggatcttc
     1261 tccgcgtgtg cctcgccgag cgccccgccg aagatccgga agtcgtgggc gtaggcgaag
     1321 accgtgcgcc cgtcgacctc tccccagcca gtgaccaccc cgtcggtgtg gggccgccgt
     1381 tgctccaggc cgaatccggt ggcccggtgc cggcgcaact cctcgatctc cgtgaaggtg
     1441 ccctcgtcga agaggagcgc cagccgttcg cgcacggtca gttttccctt ggcgtgctgc
     1501 gcctcggtgg cgcgctcgcc ggggccgcgc cgcacgcgct cgtgcagtgc ggcgagttcg
     1561 gcggcgcggt cgcgcaggtg gccgtcggcc ggtgccgcgg agttcagggg cgattcctcg
     1621 acgacgctca tggggagagc gtgcgcaccg tcgctcaaga cgggctcgac ggcctctgga
     1681 cgcgcgggtg gagcggggct cgaccgggcc cgtccacgct cgcgtcatga cgcgtccgac
     1741 gcagcgctcc gtcgtcctga tgttcccggg caccggggcc cagcacccgc ggatggcggc
     1801 tggtctctac cggcgggagc cggtcttcac ggccgccgtc gacgcggttc tgggtgagct
     1861 gggcgccgag ggcgaggcgg tacgtgccga ctggctggcc gacgtgcccg ccgtgccgct
     1921 ggaggccgac gcccggtcgg cgcccctgct gttcgccgtg gactacgccg tggggcggct
     1981 ggtggagagc tggggggtgc ggcccgcggc gtacgtgggg cacagcatgg gggagttcgc
     2041 cgccgcgacg ctcgcggggg tgttccggct ggaggacgcc gtgcggctgc tgtgggaccg
     2101 ggtggagaag cagcgcgcga ccccggtagg cggcatgacc gcggtggcgg cggcgcggca
     2161 cgaggtggcg ggatacctgg gggcgggtgt ggtcgtgggc gcggtcaacg gcccccggca
     2221 cacggtgctg tccggccccg aggcgccgct gcgcgcggtc gaggagcggc tcgcctcgga
     2281 cggcaggacg ttccggcggc tcgccacccg caccccgtac cacagccccg cgctggcgcc
     2341 gctcgtcccc ggcggggccg ccctcgtcgc cggcatgccg ctctccgctc cccgcaccct
     2401 tctctactcc gcctacaccg ccgggccgtt gcgcgaacgg gaggcgctgg cccccgcctt
     2461 ctgggcggcc cagccgacgg ccccggtgct gttctggcag acgctggacc gggtgctgcg
     2521 cgacgacgac cggctgctgg tcgaggccgg gccctcgcac agcctctcgg ttctggccag
     2581 gagccatccg gcggtgcgct ccgggcgcag cacggtggcg accacgctgc ctccccgggc
     2641 gcaggggccc cgggcggacc ggctcagcct ccgcgcgctc cgtgcgtggt tgagcgcgga
     2701 gggggcgctg ccggtccctc cggggccggg tcactccgga acgttgccgg tggagctccc
     2761 gctctcgtag gggccggtca cgccgtcgta cgcgaggtgc agcaccatgc cgtcgcgtgc
     2821 gtggtcgaga ttgtggcagt ggtccatcca caggccgggg ttgtcggaac ggaaggccac
     2881 ctcgtagcgc tcgccggggg cgacgttgag ggtgtcggtc caccacgggc tgccggtggc
     2941 cggttcgccg tccctggaca gcacgagcat gcggtggccg tgcagatgca tcgggtggtc
     3001 gtccaggctc cggttgagga aggtcgtgcg caccaggtcg ccctcctcga cgacgagggc
     3061 cgggatgtcg gggtggaccg cgttgttgac ggtccacagc accatggggc tgccgtcgtg
     3121 gaagccgagg ctgttgccga ggaccaggga gaagtcgcgg tcgaaccgtg gggaccggcc
     3181 gagcggaccg gcgccggccg ccgagccgta gtgcagcggg tcgaagagcg gcccgctgac
     3241 ggcggggacc cggccggcgg ccgaggggtt cggggcgagc tgcagggacg cggtctcggt
     3301 gcggcccgtt ccgtaggcgc cgtcctgccc gcacccctcg aagccctggc cgtcggcgga
     3361 ggcgttggcg tcgccgacga ccgtcagccg gaccgggccg tccggctgac ggtaggtgag
     3421 gtcgtaccgg ccgccgcccg ccaccctcag cagccggccg cgcacctcgg aggctccctg
     3481 gacttcggtg ccgtcgatcg ccgcgaccgc gaaggaggtc cccgcgaggg agtacgtacg
     3541 cgggcagttg tccgcgttga ccaggcgcag ccgcacctcg gtcccggccc ggaccttctc
     3601 cgcgcgggtg cgcgtgtcgt cgccgaaggc ggtacgcagg gtgccgccga ggccgttggt
     3661 gccgctcagg gcaccgccgc cgtgcggccc gcccggggag ttccgggccg tccccacggg
     3721 ccaggcgtgc gcgaccacgg tccggtcgaa cggcgcccgt tggtccttcg acggttcctc
     3781 gaccaccagc gccccgaaca ggccgcgcgc cacggcgatg ctcgactgct ggtgggagtg
     3841 gtaccagaag gtgccggccc ggtcggggcg gaagcggtac acgtggtgcc ctccgggcgg
     3901 gacggcgtcc tgggtgaccc cggccacgcc gtcctcggcg ttggggacgt cgacgccgtg
     3961 ccagtgcagg gtgacgccgt ccgccacgtc gcggttgacc agcaccacct ccaccagctg
     4021 gccgcgcctg acccgtagct ccggtccggg gaggctgttg ttgaaggaca gggcggccac
     4081 cttctcgccg gacgccaggc gcagggtgcg gtcggtcgcc gtgagggtga accgccggtc
     4141 cggttcaccg gagcggtcac cggtcaggtc gacgaccgag cgggtggggg cggtcccgga
     4201 gtgcgcgtgc gccgaggcac tggtccggtc gggcagccgg ctctgtccgg cggcgagcgt
     4261 gcagccgccg gcggtgagga cggcgagccc ggtgaccgtc gcggtggccc gcaccagctg
     4321 ccgcgcacgc gggacgggcc gtccgccacg agcctccagg gcggcccggc ggcgccggtg
     4381 gagcaggagc aggccaccgc agacggcgcc gcccagcagg atgtggacga ggaacgggcc
     4441 ggtgtacggc ggtgccggcg ggtgcagcgt gcccgcggct ccgagcagcg tcgtcgcgca
     4501 gcacgcctgt accgggacca cgaggcggtc gcccgcggcg agcgcccgca ggccgggcgg
     4561 gagcggcgag ccgtccgggt ccgacccggc cgccggtgcc gcgcgcagga cgcgcaggta
     4621 cgcgggaacg gccagtgccg ccaccgcgac ggcggcgagg accgggggca gcgcgccgaa
     4681 cagcacgtag tccgcgcccc cgagccagcc ggcggtggcg acgagcccga gggcgaggcc
     4741 tgcccggacg gccagggtca gcagggcgac cgtgagcaag gccagtccga gccgcgcccg
     4801 gcgccggagc gcggcggcgg ggcggatggc cagccgtctg gccccgcgtg ccgcgcaccc
     4861 ccagacgacg gccgtcaaca cggcccagag gatgttctgt tcgaagaggt tctccaccat
     4921 gggggcagcg tgccgtggcc tcttcgagcc tgcctcgagg cggctggacg atgctcacgc
     4981 ccggccggag cggctcgccc ggccgagtcg ggcacgggag ggagcacgcg atggagctga
     5041 ggcgcagtgc gctggtgacg ggtggttcgc gcggcatcgg ccgcgcggtc gcggtacggc
     5101 tggcacagga cgggtacgac atcggcttct gctcgcgttc cgccgacgag gcggcgctgg
     5161 agacggcccg gctggtcacc tcggccggtg ctcgggcgca ccacgtggtg tgcgacgtca
     5221 ccgacgccga cgccgttcgg accttcgtcg cggaggcgga ggagaagctc ggcccggcgt
     5281 acgcggtggt caactccgcg ggggtgctgc gggaccggcc gatggccctg atggcggcca
     5341 gggactggca ggacgtggtc ggtacgagtc tggacggggc cttccacgtc tgccgggcgg
     5401 tcgtgcgcgg gctgctcacc cgcagggcgg gggcgctggt gaacgtctcc tcggtcatcg
     5461 gggtgtacgg caacgcggga cagaccaact acgccgccgc caagggcgga ctgaacggcc
     5521 tgacccgtgc cctggccaag gaggtcgccc cgtacggcgt ccgggtcaac gcggtggcgc
     5581 ccgggttcat cgagacggag atgctcgacg gcatgacggc caaggcgcgc gaggcggccc
     5641 tcgggaagat cgccatggcg cggttcggca gcgccgagtc cgtcgccgcg ctcgtcgcgt
     5701 tcctcgtctc cgacgccgcc gactacatca ccggccaggt ggtgcagatc gacggcggga
     5761 tcgccctgtg aggagcgcgt catgactctc gacgagggga cgtccgcgga ctccgtcacc
     5821 cggaccgacc cggagcggcc gctccggtcg atgttccgtg agcgctggtt ctccaccctc
     5881 ttcatgaccg acatgtggga gcggttcagc ttctacggca tgcaggcgct gctcttcctc
     5941 tacgccacgg cgccggtcgc cgaggacgga ctgggcctga ccgccggtac cgcgggagcc
     6001 ctgttcggcc tctacgtgtc gggttcgttc ctggcggcca tgccgggcgg ctggctgggc
     6061 gaccgggtgc tgggcacgca ccgggccatg ctctgcggtg ccctggtcat catggccggg
     6121 cacctgtcca tggccgttcc ggcccaggcc accttctacc tcggcctggt cctggtggcc
     6181 tgcggcaccg ggctgctgaa gcccaatctg ccggtcatgt tcgaccagat gaaccccggc
     6241 gcgtccagca gccggcggca ggcggcgttc tcgctcttct acatgagtat ccaggtgagc
     6301 gccctggtgg ggccgctggt cacggggatc ctcggggaac gggtcaactg gcacctgggg
     6361 ttcggcgcgg ccgccgtggg catggccttc ggggtgctcc agtacctgca cggggcaccg
     6421 tcgctgcgcg gagcggcgac gggccccagc aggcccctgc cgcccgccgc tctgcgccgc
     6481 ctggtccgcc ggtgctgggc ggccctggcc ggcgccgtgc tgctgggggc gggactggca
     6541 ctctcggggg gtctgccgct gcgtccggtc ctggccttgt gcgggctggc ctccctggtg
     6601 gcgcccgtct ggtacttccg gcggctgctg cgggaccggt cgctgggcga ggccgaacgg
     6661 gcgcgggtgc gcggctacgt gcgcgtcttc gtgccgtcgg tactgttctg ggcgatgttc
     6721 gggcaggtgg gctcggtctt cagcctgttc gcccgggagc acaccgatcg cgaggtggcc
     6781 ggattcagcg tgccggcgag ctggttccag tcggcgcatc cgctcttcct gctgttgttg
     6841 gcaccggtgt tcgcctggct ctggctgagg atcggggcgc gtgcgggggt ggcgcggaaa
     6901 ttctccgtgg ggctgctctg cgcgggcggc ggcttcgcct tcctcgccgt cggcgcctgg
     6961 ctcgcctccg gcgggcgggc ggtggtgtcc ccgttgtggc tgctggccgc cttcctctgc
     7021 atgacctgcg gtgagctggt cttcgggccg gtcggactga gtaccaccgc cgagtcgacc
     7081 cccgcaggcc acggcagccg gatgatgggg ctcttctacc tcggggcggc gctgggcgcc
     7141 ggtgtcggcg ggcagctgtc gcacctggtg ggtgtcgtcc cgctctggag ctacctcgcg
     7201 gggttcgtcg tggccgcagt ggccaccgcg ctgctgttgc cccggcgaac ggcggaaatc
     7261 tgacgtcgag ctggcctgga ccggccctca agccgcccgg gccagcatca cgtcccgaca
     7321 gcccgccggc cgcgcgtcgg cacggtcccc gtccgctcac ggggcccatg ggccgtcctg
     7381 accgcccgac cgctccgggc cgtatccgaa ggagtcctca tggcgcaccg caccctcatc
     7441 gtcgcgcgga tggaccacga cgacgccgac aaggtggccg cgctcttcgc cgagtccgac
     7501 gcgaccgagc tgccgcacat gatcggcgtc cagcggcgca ccctgttccg cttccagggg
     7561 ctgtacttcc acctcgtcga ggccgaggcg cccatcaacg gcgacctcta ccaggcccgt
     7621 agccacccgc tctaccagga catcaacacc cggctccagg agttcatgac cccgtactcc
     7681 ccgtcgtggc gggagccgaa ggactccatg gccgagccct tctactcctg gacgccctga
     7741 ccggccggcg gcccgccccg ccgccttctt ccgtgaaccc ccgtccccac gtgtggagca
     7801 cctatgcaga cctcagacct gatcaaagtc gccgtcgacg acgtcgagcc caaccgggcg
     7861 cgcggcggcg acctccgtgt cctgctcagc cccaagacct gcggagccac ctcggggttc
     7921 atgggcgtcg gcgccctgga gcccggcgag ttcgtctccg agcactacca cccgtactcc
     7981 gaggagttct tccacgccgt cgagggccgt gtcctgctgc gggtcgacgg ccgcgaactg
     8041 gttctggagc ccggcgagtc cttcatggtc ccgatcggcg tccggcaccg gatcgagaac
     8101 ccggggtccg gcacggcccg cgtcgccttc ttcctgagcc cgctcgcccc gcgcccggag
     8161 ctggggcacg tggactgcga gccgctgccc ggcgagggcg ctccgcccga ggtggggggc
     8221 gcgcgatgac cgcacgtgcg gtgatcaccg gcatcggcgt cgtcgcgccg ggccggccgg
     8281 ggcgggagaa cttctgggag atgatcgtga agggccaaac ggccacacgg cgcatcaccc
     8341 tcttcgatcc ggcgcctttc cgcagccgca taggtgccga gtgcgacttc gaccccgagc
     8401 gcaacggcct gtcgtaccag gagatggccc gcaccgaccg ggcgggccag ttcgcgatcg
     8461 tcgccgcccg ggaggcggtc gcggacagcg gcatggacct cggcgccgag aacgcgcatc
     8521 gggtgggggt cagcgtcggc aacggcgtcg ggaacgccat ctccatggag caggcgtacc
     8581 ggaccgtcag cgacaacggc cgccggtggc tggtcgacca ggagtacgcg gggccgcacc
     8641 tctactcgtc cgtgatgtcc agctcgctgg cggccgaggt ggcgtgggcg accggcgcgg
     8701 agggcccggc gacggtggtc agctcgggct gctgcgcggg catcgatgcg gtcgggtacg
     8761 ccgtcgacct gatccgtgag gggtcggcag aggtcatggt ggcgggcgcc acggacgcgc
     8821 ccatctaccc gatcaccgtc tcctgcttcg acaccctgcg ggcctcctcc accagcaacg
     8881 acgaccccga gcacgcctgc cgtccgttcg acaggcggcg caacggcctg gtgctcggcg
     8941 aaggctccgc cgtcttcgtc gtcgaggagc tggagcacgc ccggcggcgc ggcgcccgga
     9001 tctactgcga ggtggcgggc tactcggccc gcgccaacgg ttaccacatg accggactgc
     9061 ggccggacgg gcgggagatg ggcgaggcga tcaccgccgc gctcgacgag gcccggatca
     9121 acccggacga ggtcgactac gccaacgcgc acggctccgg caccaagcag aacgaccgcc
     9181 atgagaccgc ggcgtacaag cgcagtctgg gcgagcacgc ctaccggatt ccggtcagct
     9241 ccatcaagtc catggtcggt cactcactcg gctcgatcgg ctccatcgag atcgcggcca
     9301 gcgcgctggc catcgaccgc gggaccgtac cgccgaccgc caactacgag gagcgcgacc
     9361 ccgagtgcga cctcgactac gtgccgggca cggcgcgcga ggcggagctc gacgtggtgc
     9421 tcagcgtggg cagcggcttc ggcgggttcc agagcgcggt ggtgctcacc tcaccgagga
     9481 ggatcgcatg accgggcccg tcatcaccgg ggtgggcgtc gtggcgccca acgggctgga
     9541 ccgtgaggca tggtggcagg ccacgctgga cgggaagtcg gggctcggcc ggatcagccg
     9601 gttcgacccg tcgccctacc ccgcgcaggt cgccggggag gccaccgggt tcgtcccggc
     9661 cgatcacgcg ccgcgccggc tggtcagcga gaccgacgcc atgacgcagt acgcgttcgc
     9721 cgccaccaac gaggccctcg ccgacgccgg ggtggacccg gccgcgctga acgacctgga
     9781 catggcggtc atcaccgcca actcctcggg cggcgtggag ttcggccagc gcgaactgga
     9841 gaagctctac gccgagggac cgcaggccgt cggcgcctac atgtccatcg cctggttcta
     9901 cgcggccacc accggacagc tctcgatccg gcacggcatg cgcggcccct gcggcgtcct
     9961 ctgctccgaa caggccggcg gcctggacgt gctcgcgcag gcccgccggg tcctggcgaa
    10021 gggcacccgg ctggtggtct ccggcggcac cgacgcctcg ctctccccct acggactggt
    10081 ctgccagctc gccaacggac ggctcagcga cgagtcccgg ccggagcgcg cgtacctgcc
    10141 cttcgacccg cgggcacgcg gctacgtgcc aggggaggga ggtgcgatcc tcaccgtcga
    10201 gagcctcgac gatgcgcggg cccgcggcgc cggccggatc tacggccagg tcgccgggta
    10261 cgcggccacc ttcgatcccc gtccgggctc agggcggcca ccgggactgc ggcgcgccgc
    10321 cgaactggcc ctcgccgacg cggggaccgg gccggagggc gtggacgtgg tcttcgccga
    10381 cggcgccggc ctgccggagc cggaccgtca ggaggccgag gccctcaccg ggctgttcgg
    10441 gcgaggcggt gtgccggtct ccgtccccaa gacgatgacc ggccggctct acgcgggcgg
    10501 cgcacccctc gacgtcgcgg cggcggtgct cgccctgcgg gaccaggtcg tcccgccctc
    10561 ggtcaacgtc cgtcccgacc ccgtccacgg cctcgacctg gtcaccgacc ggccgcgtga
    10621 ggcccgcctg cggaccgccc tggtcctcgc ccgtggctac ggaggcttca acgccgccgt
    10681 ggtcctcaga tccgtctgac cgccggcgtc cgctcgcacc accccgcgcc ggccccgctt
    10741 tcgcatcccc aggaggacaa cagatgagca ccatcagctt caacgacctc aagaccatca
    10801 tgagccgcag tctcggcgag gtggacggga ccgaactcac cgaggccgac ctgaccaccc
    10861 ccttcaccga gatcggctac gactcgctcg ccgtcctgga gatcgccagc cagctccagc
    10921 gggagtacgg cctccagata ccggacgagg ccatcgagga gatggacacg ccgcaggccg
    10981 tcatcgacta cgtcaacacc agcctggcgg gggtctgaca tggccgcctc gaccgacaac
    11041 tccgtggtcg tcgacgcccc catggagctg ctctgggaca tgaccaacga catcgagtcc
    11101 tggcccggcc tgttctccga gtacgccaag gcggagatcc tcggccgcga cggcgcgacc
    11161 gtcaccttcc gtctcaccct ccaccccgac gagtccggcg ccgtctggga ctgggtttcc
    11221 gagcgcaccc ccgacccggc cacccgcacg gtccgcgccc ggcgcatcga gacgggcccg
    11281 ttcgtccaca tgaacatcct ctggacctac gccagcaccg acgcgggggt ggagatgcgc
    11341 tggcgccagg agttcgaggt caagccgggt ctgccgttcg gtgacgccga gatgaccgag
    11401 cgcctcaaca ccaacacacg gcgggagatg gcccgcatca aggagctggt ggagaaggcg
    11461 gcagccgagc ggcgggcggc gcggtgaggc ccggactgcg ggtgctgttg cgcatacgcg
    11521 tcgccgaggg ccaggaggaa cggttcgagg agctgtggcg cgcccacgcc gagaccgtcc
    11581 gtagcttcac cgacaaccat ggtcagcaac tgctgcgtac gcgtggcgag cgcggcagct
    11641 acaccgtgct gacggactgg acggacgagc cgtccttccg ggccttcgag cgcagccccg
    11701 agcagcaggc gtacctgcgc gagctctggg ctatccgcag cggcggcgag atgcagctgc
    11761 tcgacctcgt tcacaccctc tcaccggcca ccccggccga agcctgagaa ccgaaaggac
    11821 ccgcatgagt gtgcagcagg aacaggtgac cgaactgatc gacctggtcc agtcggtgcc
    11881 ggccaaggag gtcgaggggg tggtcgcgac ccgccccggt ggtgtcgacg gcgccctgac
    11941 cctcatcttc gatctgctgg tgtcggagtt caacccggcc aaggccgagg gcgagaaggg
    12001 ggtgttccag ttcgacatcg cctgcgccga cggcaggaag caccaccacg tggaggtcgt
    12061 ggacggcacc tgccggaccg gtcagggagt gcacgaccac cccgacatca ccatcggcat
    12121 caagttcccg gacatgctgg cgatgggggt gggcaagctc cccggcgcga aggcgttcct
    12181 gaccggcaag ctgaagctcc gtggcagccc gctgatgggc acgaagctgg gtgagtggtt
    12241 cgaccacccc gagacctgac ggacgccgag ggggccgccg tccacgcctg gcgcggacgg
    12301 cggccccttt ttcgttcctc tcccgttccc ggtcagccga cgccgagcac ggacatgtgg
    12361 gcgagggaga acatcgcctg ctcatggacg cgcgccagat aggcgtcccg gtccgggtgc
    12421 cgctccgggg cccggaggta gggcacgagc cacgactccg cgtcctgccc gaagcagcgg
    12481 tccgcgaggt aggacaccac gtcgtagggg tgaccgtcgt actgcacgac ccgcaccagc
    12541 gtgtcctcgt gcaggaacag tgccgtgcgg acgatggccg gatactcctc ggccagccgc
    12601 aggaaggccc gtacgttggc cgtggcccgg gcggccgcca gctccgcgcc ggcccccgcc
    12661 cgcagcgggt agcgcagggc gaccgtcccc gcggcggggc gttcgtcggg actgtgctgt
    12721 tccaggaccg tcatcaggct gcggtggaag tgctcccgga acccctcggg ggtctcggtg
    12781 tcacggggtt cggcgaggta gggcaggatg gcccgctccg cgtcgtgcac gcccttctgg
    12841 accgacatgt ggtgggcgat cctcgcagcg ccgacgccgt cgtggtggat cacccggacc
    12901 atcacgtcct cctggacgaa caggcccgtg ccgaggagca tcccgaccgt ctcacctgtg
    12961 ccgttcttga tcaccgggga gtcgacccgg gtgaagttgt ggggtgagaa gacctcggtg
    13021 agttcctcct cgtggccggg agcgacgcgg taggtgacgg cgtccagcgg catgacggta
    13081 actcctctgt cgaagggggg cggtggggaa tcagcgggcg gtgagcaccg cgaccgtgac
    13141 ggcggccagg gcgagtgccg ccaggaccgt ccgcaggcgg tgccaggcgc gccactgcgg
    13201 acgggggtcc acccaggacc ccgcggccgc gaggccgctc agcgagcggt tgatcgggac
    13261 gttgccgagg tgtgagaccg cctgcacgcc gatgagcagc accgaggcga gggggaacag
    13321 gacattcccc ggtgccccgg cgaggaacgc gagggcgaac ccgctcagcg tcacgatgtt
    13381 gaccaggatc ggcatcagcg ggtggtaccc cttgccgagc agcgcgtgtg cccgcaggta
    13441 ttcggcgcgt cccatcgccg acatggcggg accgacgctg acggcgacgg cgacgaagac
    13501 ccccgtgacg gtccccgtcc cggccagcac gactccgctc agcacttcct cgagcatcac
    13561 gactcctgat cggtggtggg tggtgccgcc accctggcgc cgcctgctcg attcgctgtg
    13621 gagcggcgct cgacgggccc gcccgccgtc cgccccgcga gccgtcgcgc ccccgccggc
    13681 ccggtccgcg cccgggcgtt gatcatcgag ccgtcttcga ggccgtttcg accaccgggg
    13741 ccgaaggtcg gggccggagg cggccgcacc ccggcggcgg cctgggcagg aggcagaaac
    13801 gtggcctggg aacaggtact catgccgccg gcgctgctcg ccggcgggct cgcggccggt
    13861 ggcctggcga tctcggtgct ggccgcgccg ttgttcacca ccctcccgac cgtgatgtac
    13921 gtcccggtcc accagggcct ggtcacccgc ttcgatccgt tcatgcccgt gtcgctggcg
    13981 agctgcctgt tctgcgacgc cgccctggtc cttgcggccc agggcggggc ggtccggctg
    14041 ctggccgcgg cggcggcgct gctgctggcc tgcgccatga cggtgtcgct caccaagaac
    14101 gtgccgatca accggtggct ggcgaccctc gacccgcggg cgctccccgc cgacttccag
    14161 cgacgcgacc cccgcacacg gtggatccgc tggaaccgcg tacggggcgc tctcgcggtg
    14221 gcggcgctgg tggccaacgt cgcggcggcc gcgcttctca tctgaggccg gccccgtgcc
    14281 ccctcgctcc catccctcga ccgctcgttg aaggagacct cgtggacacc atgaccggtg
    14341 tggtcgggcc ggcgttgacc gcctcgttgc cgccccacgt acgcctgttg ctgctgacgg
    14401 acggcaaacg gatatcccgg gtgctgcacg tcctggccga actggccgtc gccgacgagc
    14461 tggcggacgg accgctgacc gtcgccgagc tcgccgtacg taccgacgcc cacccggact
    14521 ccctggggcg cgtgttgcgg gtcgccgccg cgttcggcgt cttcgaggag cgggaggacg
    14581 gccggtacgc gctgaccgag ctcagcgagg tgctccgctc cgacgtgccc ggcagccagc
    14641 gggacatggt gctctacaac ggcaccgaga tgctgtggcg ctcctacggc tccctcctgc
    14701 acacggtgcg gaccggccgg cccgccttcg aggcggtcta ccagcaggac ttcttcacac
    14761 acctggagga gaacccgcag gcgggagccc tcttcgaccg ggcgatgacc gggatgagcc
    14821 gggccaccgc gcggatgctc ctcgacagtt acgacttcgg gcggttcctc cgcctcgcgg
    14881 acgtgggagg tggccgcgga ctcttcctcg ccgaagtgct cacccgtcat cccggaagcc
    14941 ggggaacgct gatcgaccgg ccggcggtga ccggggaggc ggccgggctg ctccgcgagg
    15001 ccggggtcgc cgaccgggtc gaggtggtgc ccggcgactt cttcgaggag ctgccgaagg
    15061 gccatgacgc ctatgtgctc aaggccgtgc tgcacgactg ggacgaccgg cgcgcggccg
    15121 ccatcctcgg ccgggtccgt gacgcgctgg cgggccgccc ggacggccgg ctgctgatct
    15181 gcgagttcct cgtcggcccc gccaaccagt gggaccgcgg caaattgctc gacctggaca
    15241 tgctggtccg cttcggcggc cgtgagcgcg acgcggacca gtggagggcg ctgctggcgg
    15301 ccaccggctt cgagctggtg aacgacccgg tgcccgggcg ctgggcggtc ctggagtgcc
    15361 gcccggtacc ggccgacggg tgagtcaggg cccgcccggc acgagacgga cgcgacccgc
    15421 cacggcgggg gcgcgcgacc gcgtcgccca cgacggcgag gcggcttccc cacgcgacga
    15481 gacgacggag gagatcatgg aacttcgact ggtaggcacg aacgcgctgg tcaccggcgg
    15541 tacccggggt atcggccggg ccatcgtgct ggccctggcc aaggccggtg ccaccgtggt
    15601 gacctgctac cgcaccgagg gcgaggccgc cgacagcctg gcccgcgaac tgaaggagct
    15661 ggggggtgac cacgccctgg tccgcgcgga cgtcggcacg accgagggcg tggaggcggt
    15721 gctggccgcg tgccgcacgc gtttcgagac gctggacgtc ctggtcaaca acgccgggat
    15781 catcagccag gtgcccttcg cccagctgcc cttcgaggag tgggagcggg tcgtcacgac
    15841 caacctgacc ggccccttca tggtgatcag caaggcgctg ccgctgctgc ggaaggggtc
    15901 ctcggtgatc aacatcggtt cgcgcggcgc catggcgggc attccgctgc gtggccacta
    15961 caccgcctcc aaggcgggcc tggtcgggct gaccagaagc ctgtgcaagg aactgggcgg
    16021 caagggcatc cggttcaacg tggtggcacc gggcgtcatc gacacctcgg agccggagga
    16081 gctgacggag gagcagcggg ccgcgtacga cgagcgctac ctgcggatga tggcgctggg
    16141 ccgcttcggg cgccccgacg agatcgccgg cgcggtcctc ttcctcgcca gcgacctgtc
    16201 cacctacgtc aatggcgaga ccctgcatgt cgacgggggt gtctgaggtg gcggcggagc
    16261 gtgtggggtc cttccgggta ctgctgaccg tgcaggtgaa gccggggctg gaggccgagt
    16321 tcgagaaggt ctgggcggag ggcagcaagg aggtcacgtc ccagtcggcc aacctgggac
    16381 acagcctggc gcgcagcgcc cgcgaggagt ccgtctacta cgtgaccagc gactggacgg
    16441 acaaggagtc cttcctcgcc ttcgagagca gccccggaca cgtcgcccac cgggagaagc
    16501 tccacccgta ccgtacgggc ggggccctgg ccatgatgca cctggtgggg gtggcctgat
    16561 ggacggtacg acgagccggg tcagggtcat gctgtacctg cgcgcgagcg aggaccaggc
    16621 gccggccgtg gcggaggcgt accaccggat cagcgcggac ctggcgggca cgcccgggct
    16681 gcttggcaac gagctgctgc gggaggtcag cgacccgggg gccttcgccg tgctcagcga
    16741 ctgggagagc ctgccggcct tccaggcgtg ggagagcggc tcggcgcacc ggggcacgac
    16801 ctcgccgctg cgggagtacc aggacagcgc cagggcacgg cccttcgccc tgttcgaggt
    16861 ggccgccacc tactgaccac cggcaccggg acggacggcc gtgccgcgga gagcccccgc
    16921 tctccgcggc acggccgtcc tcgcgcccac cgttcgtccg ggcgggagcc gggcgggcac
    16981 gcggcagagc gggcgccccg gacgcgaacg cgtccggggc gcccgctctg ccgccgggat
    17041 caggggagcc ggacgacctg gcccgcgtag accagccccg ccccgaagcc gatcagcagg
    17101 gcgagcccgc cgctgggggc cttgccgccg gccagcagct cctccatggc cagcgggatc
    17161 gaggcggcgg agctgttgcc gctggtgacg atgtcccggg ccacggcggt gtgtgcgggc
    17221 aggccgagct ggtcgacgac gtggtcggtg atgagcatgt tggcctggtg cgggatgaag
    17281 gcgtcgaggt cgtcgacggt cacaccggcc aggtccagca tcttcctcgc ggcgggcacc
    17341 agttcgttgg tggcccagcg gaagaccttc cagcccgaca tggtgatggc cggccgtgcc
    17401 tcgggccgca ggccggtacc gtcgtgccag ggagcggtca tgcgcagggc ggcgttgcgc
    17461 gtcccgtccg cccgccagac gacggggccg atcccgggct cgtgcgaggg cccgacgacc
    17521 acggcaccgg cgccgtcggc gaagaggaag gcggtgtcgc cgtcctcgtg gtcgaggatg
    17581 tccgtcatcc gttccgcgcc gatgaccagc acgtggtcgg cgcggcccat ccgcacctgg
    17641 tcgccggcga gcgccagggc gtggcagaag cccgcgcagg cggccgagac gtcgaaggcg
    17701 gcggcccggt ccgcgccgag ccggcgcgcc acctcgaccg cgacggccgg catctgctcc
    17761 atggaggtga tggtggcgac gatgaccgtg tcgatccggt ccgcggagac gcccgcggcg
    17821 gccagcgcct tctcggccgc ggcggtggcc atggcgggca gggtctcctc cggtccagcg
    17881 tagcggcggg accggatgcc cgaccggcgc tcgatccagt cggggtcgag ccccgtccgc
    17941 ccggcgatct cggtgttggg gacggaccgt tcggggcggt ggacgccgac ccccagcagg
    18001 cggctgtggc gcaggacctc ggtgtcccgg atcgcagtca tgcttgtcct ttcctgaagt
    18061 gacgaagcgg ccccggcacc ggtccggggg tgcccggacc ggcgcgggag ccagggtggg
    18121 gtcagcggtc cgtccgggac gcggcagcgc ccgggcgcgc cttcttcccc cagcgggtcg
    18181 ggccccaggg cttgtacgtg gagacggcgg tcatgaacac cagggagacc acggccaggg
    18241 cggccgatcc ggccatcgac cagcccacgg tgtcgagttc gcccccgcgc accggggctc
    18301 cggcgtcgac gagttcattg gcgcgcagga tgagctggtg gatgacgccg aacccgagga
    18361 tcatcacgcc catggtgagg aagaacttca cggccaccca acggcgctgg agcagtcccc
    18421 acttggtccc cgccccgacc acgatgccgg tgatgagggc gaacatgctg gtcatgccga
    18481 gaaagatctc gtctagcatc gacatggtgc ggtacatcgc ggcctgctgc tcggcgctgc
    18541 ccgtggtggc gcccgagacc gacatggcga acatgccggt caccagcccc agccagccca
    18601 ccgagatcgc cacgtgggcg gtgaggacga tcttgcgcag ccgctgcggg acggtgcggc
    18661 tctgccggcg cacggcgctc atccaacggt tgacggacgg caggaagagc agcaccaggc
    18721 cgaccacgga ggtcacgagg ctgatcacgg ccagggaacc ctgcagtgcg cccaccaggg
    18781 gccgcccgcc cagcccggcc aggcccagac cggtgaagac gatgcccagc gaggtgaaga
    18841 ccgtcagcag cacccgcccc cactggcggc cggccctgag catctcggcg aagaatccga
    18901 acagcgcgca gaacgcgatg gtcaggacga ggtccccggt cgtggcggca ccggccaccc
    18961 cggtctcgat ctggtcggcg atctcgaaga cgttgctggc gatggccgcg agcgtggcca
    19021 cgatcaccat ggcgtaggcc cagcggacgc cgcccggtgg tccagggggc ggcgccgacc
    19081 cggcggcggg cccacggtgg tcggaccttg ttcccggtgc gggcggcctc tccgcctggt
    19141 ctgtcgtact cacccgtcgc gcctccttct ggaccaggcg cggcctcccg cgacagcggg
    19201 acactgacgc gccgtcggtt tgcggcttct gacgcggtca gcctcagggg gagggctcga
    19261 aactcacttg aaggccggtg gacgcgaggg ccgcgcgctc cggcggcggt cagccgtggt
    19321 ccgcctcgtc cagggagtgg acgaacttgg tgagcagccg ggcgaactcc cgctgctcgc
    19381 cctcgtccca gtccccgagc accttgccgt agaagtcctg gcgggtgcgg tgggcggcac
    19441 tgacggcctc ttcgccggtg ggcgtcagtt ccaggcagct ccgtcggccg tcctcctggg
    19501 aggccacccg gcggatgaag cccgacctga cggcgtcggc gacgatccgg ctggcccggg
    19561 acgggtcgat ggcgaggcgg tcggcgatga aaccgacggt gacgtcgcgg ccgctctgtc
    19621 cgccgccctc gtcgacggcg tccacgacgg cgagggtgtt gaggtcgatc gggtccgcga
    19681 ggcccttcat gacggggcgc gcgaggctgc gccgggactg ccggcggcgg atccggatca
    19741 tcgcggcctc gatggcggtc agcaccgcgc cgtcgttcct gccggtcgtc gcaccggtct
    19801 tctctgcacc gtccacgcct tcaggctact ggcatacggc tggactgagc attcctgggt
    19861 gtggcaccat tatgtgctga acgcatgcat gtgcttgatg catcattctc tgtcgcgttc
    19921 ctgcgaccga aggaggctga ccatgtccgc aactcccgcc gccgaaaccg gcggaaccgt
    19981 gcgcaccaga gcgatcgccc tcgtgggggc cgtggtgctc gccgcgctga tctggctcct
    20041 cgcccacgag gcgttcgggg tcgacctgag gaccccggac ggccccggtg ccaccaccac
    20101 gagcgagctg ccgttcgcgg ccgtgcccct ctccgtcctg gtggtctccc tgctgggctg
    20161 ggcgctgctg gccctcctgg aacggttcac cgcccgggcc cgcaccgtct ggaccgccgt
    20221 cgccggggcg gtgctcgtga tgtccctctt cgccccggtc ttctcggagg gcctgaccgc
    20281 gggcaaccgc ctcacgctcg tctgcctgca cctggcggtc ggcgcggtgc tgatcccggc
    20341 gtaccgcaag ggtgcccgcc aggcgtgatc cgggccggaa ccatccagcg cccctccacg
    20401 cggtttcgag cggtgcggga aacgctggac gccgacggca agccaaggtg acggaaggag
    20461 atcccgtatg tgcggcatcg caggctgggt ggtccgccag gacggaaggc cccgggagga
    20521 cccggcggtg gccgaggcga tggccggcgc catggcctgc cggggccctg acgagcaggg
    20581 tgtccgcggc ggccggcacg tgacgctggt gcatacgcgg atggccgtca tcgacctgct
    20641 cggcgggcgc cagccgatgg ctgcggacga gagcgaggac ccggccgcca cgctcaccta
    20701 ctgcggcgag atctacaacg ccgccgaact acgctccgac ctggccggac gggggcaccg
    20761 gttccgcacc cgcagtgata ccgaggtggt gctgcgggcg tatttggagt ggggcgagcg
    20821 ctgccccgag cggctggagg ggatgttcgc cttcgccgtc tgggacgccc gcacgcgctc
    20881 cctgttcctc gcccgcgacc gcttcggcgt caagccgctg tactacgccg agaccggcga
    20941 cgggctggtc ttcgggtccg agcccaaggc gctgctcgtc cactcggacg tgagccccga
    21001 ggtcgacctc gacgggctgc gcgtgctgtt ctccatggcc cgagcgcccg gcgagtgcgt
    21061 ctaccgctcc ctcagcgacc tgccgcccgc ccacacgctg cgtttcgggc ccgacggccg
    21121 gctgtcgctg cgccggtact ggcagctgga ggcccggccg cacgaggagg atctggccgg
    21181 gacggtcgcg accgtgcgcg ggctgctgga gagcagcgtc gcccgggaac tggtctcgga
    21241 cgtcccgctg agcgtgctgc tctcgggcgg cctcgactcc agcaccgtgg ccgcgctggc
    21301 ggccagggcc ctggcggacg gcgacggcgg accggtgcgc acgaccaccg tgacgtacag
    21361 cggttacggc gacaacttcc agcccgacct ggtgcgcagc gctcccgact ccccgtacgc
    21421 ccgtgccgtc gccgagcaca tcggtgccga gcacctagag atcgagctga ccaccgccga
    21481 cctgatcgac ccggtggccc gccgcaccgt cctgcgcgcc caggacgtcc ccgccccgtt
    21541 cggcgacatg gacacctcga cgtaccaggc gttcgcgggc gtgcgccggc actccagggt
    21601 ggcgctgacc ggggagagcg ccgacgagat cttcggcggc tacagctggg tccacatccc
    21661 cgacctggcc catgaggagc aattcccctg ggtcgccttc gagcagtggc atccgggtac
    21721 gcgccggggg ctgggccagg ggctgctctc cccggccttc aaggaccggc tggacatggg
    21781 ctcgtactac gccgagcggt acgcgcaggc catgtcccgg ataccgcggc tgccgaggga
    21841 gggcgaggag gagcgccggg cccgggagat ctgcgacctg cacctgacgc actggctgcc
    21901 acggctgctg gagcgtaacg accggctgag catggtctcg ggcctggagg tccgggtgcc
    21961 gttctgcgac caccggctgg tccagtacgc gtacaacatc ccctgggcga tgaagacctt
    22021 cgacggacgg gagaagagcg tgctgcgggc cgccgcccgc gatctgctgc ccgaacgtgt
    22081 gctcgaccgg cccaaggcgc ccttcccggt gagccaggac gcgacgtaca ccaaggccct
    22141 ccaccaggaa ctcaccgagg tgctggccga ccccgcctcc ccggtcctgc cgctgctgga
    22201 cctggaggcg gcgcgcgccg tggtcgcccg ggagggggga gctgacctcc aggactggct
    22261 gcaccggatg aacgtggaga tggtgctcca ggtcgacgcc tggctccggg agctcggggg
    22321 cgacgtcgag ctgtgagccc gcaccggccg gcgggagcgc gagcaggggg cagccccgta
    22381 ggccccctgc tcgcgccgcg tcagacgcag ctgggggccg gctgcatggc gcgcagcgcc
    22441 gtccgtacca gcggggccag gcggtactgg aagaaccgtt ccgtcgtcgg gtcgctcgcc
    22501 atgccgacgc cgaggaggaa gagctcgacc agttcttcga gcatctcctc ggtctcgtcc
    22561 ccgtccttcc ccaggacggc ggcggcctgt tccaccgtga ggtcgtcggc cgcctcccag
    22621 gccagtttcg ccagcgcctc ccggagccgg ggctccagcc gggcgcaccg cccgaccacg
    22681 tggtggaacg gatgcggccg ctgctgggcc acggcggaga gccggccgcg gccgagccag
    22741 tccatgagct ggcggaccga ccagtgcggc cgcagggcca gcacccccac ggcctccagg
    22801 gtggggccgg gcaggtcgcc gcagaggtcg agcatggtgt gcaggccgcg cgggtcgtcc
    22861 aggccgcggc cgcggcccag ggcgtcgagg aagagctcca gcgacctctc gtggcccagc
    22921 ggcggcagat ccacccgtgc cttgaactgg ctgccgtaca gcctgcggta cccggcgacc
    22981 agggcggccg acccggagcc ggccggcagc aggtcggcga cctgctcggt ggtcgccacg
    23041 tcgtccacca ccaggagcac gcggcggccc tccgtccagt tccggaacat ccgggcgcgg
    23101 cccgcgcggt gcggtggcag ctcggagcgc tggtggccca ctgcctccag gaggccggcc
    23161 agcacctctt cgaccggcag cggtgcggcc cccttgccga acgaggcgta gaggcgcccg
    23221 tcggggaagg agtcgcccag gcggtgcgcg aggtggacgg tgaaggcggt ggtgcccgca
    23281 ccgggcggcc ccgccacggc gacgcactgc gggccacccg cgccctcctc cgccgagagg
    23341 acgcgtccca cgtgccgtag atcggcgtcc cggcccacca ggggcgagtc ggcgggcagc
    23401 gtcatcggcg aggcacccgg gcgcggtgcg tgcacggtcg tccggccgcc cgggaggtcg
    23461 aggccgcggt cgccggcgag tacctgctgg tgcaggcgct ggagttccgc gcacggctcc
    23521 agcccgagct cgcgggcgag gacgcggcgg atgcgctgga agacctccag ggcctccggc
    23581 cgacgaccgg cacggtagag ggagagcatc agtttcgcgt gcagcccctc tcgggtgggg
    23641 ttgtccgcgg cgagccccgt taattcactg accaggcggt ggtgccggcc gagcagcagg
    23701 tcggcgtcga gccgctcctc caggacctcg taccgctgtt cctccaggcg cagggcatcg
    23761 atcccggtga cggggccggg ggccacatca ctgagagcgg gcccccgcca tacggcgaga
    23821 gcccgctgca tcagatccgc ggcctccgcc gtcgacccct tctccatgaa gactcttcct
    23881 ctcgcggcca gttcgccgaa ccgctgtgcg tccatgcagt cgggggagac ggcgaggcga
    23941 tagccgccgg gggtggtgcg cagggcggcg ccaccgtcct cggccggccc gggacggtgc
    24001 tggtcgcaga gtccgggcag tttgcgcaac tggtagatgt acgtctggag cgtggtcgcg
    24061 gcgctggacg gcggatgttc ctcccagagc tcttcgacga gctggtgcag cgggaccgtg
    24121 gcgttggccc gcagggcgag caacgcgaga acttgtcgga ccttcggtgc ggacggtgtg
    24181 acgtgtacgc cttcgtggac gacttgcagg gttccaagca acccgatctg cagcactggc
    24241 cctcccgttg gtttgcatca ttcgtcatcc gtacggcctg atgcgcttcg tgagcgtgcg
    24301 ggcgattact tgacttctgc ttgagcggta ctcgacaagg acggtgagca ggcggggccg
    24361 gcgactctct ggtcccctcc cggctccgga cggtacgcta ccgggcgcat ctatgtgcag
    24421 gaaacatata attgctggaa gcctggaagt gctcccccgg aggaggcccc cgtgcccgac
    24481 gccatgcccg accgcccgcg acgtccggac gccgacgcac cgcccccgga cggcccgctg
    24541 ccgccccgct tccccctctt gctcgccgcg ctgctcctga ccagtgcgat gtcgatgctc
    24601 gaccagtcga tcgtggccac cgcgggcccg agcctgaccg gcgacctggg cgcgctgcac
    24661 ctctacagct ggacgttcac cgcgtacatg ctcaccttca gcgtggccat gcccgtctac
    24721 gggaaactcg gcgatctctt cggccgccgg cccgtctatc tcgcggccat cgtgatcttc
    24781 ctcgtggggt ccctggcgtg cggggcggcc ggttccatgg gccagctcat cttcttccgt
    24841 gccctccagg gactgggcgg cggcggattg caggtcagcg cgttcgccgt gctcggtgac
    24901 ctgatgccgc cccgccggcg cgcgaagtac cagggctggt tcgcgggcgt gatggtcatc
    24961 gccaacctcg cgggcccgct gaccggcggc ctcctgaccg accagctcgg ctggcggtgg
    25021 atcttctacg tcaaccttcc tgtcggtctc ctcgccatgg cgggcatctg ggccctgctg
    25081 ccccggtcca cccggggggc cgccaggccg cgggtcgacg tgctcggtac ggccctgctc
    25141 acaggcctca tcgtgtgcct ggtcctggtc accgacctgt ccggacggta cggctgggcc
    25201 cacccggcgg tgctcggcac gggcgccggc gcggtcctcc tcgctgcggt gtggacgcgt
    25261 cagtcgcggc gtgccgccga accgatcgtc ccgctcggcc tcttcgcgaa ccggaccttc
    25321 accatctgcg tggtggtggc cttcgccgtc agcttcgcct tcttcggctg tgtcaacttc
    25381 gtcccgctgt tcttccagac ggtcgagggc gtcagcgcca cccgtacggg actgctgttc
    25441 ctgcccgcga tgatcggtat ggccgtggcc acggtcgtgg cgggccaggt gatcggccgg
    25501 accgggcggt acaagtggtt cccggtggcc agtacggccc tcgcagcgct cgccgccggc
    25561 ctcatgtcgc tcacctcggc cgacacggga gcggtggccg tcagcgcgct gctggcgttg
    25621 atgggggtcg gcgtcgggct ctcctcgcag gtgacgacgc tggtcgcgca gagttccgcg
    25681 ccccggcggc acatcggcgt cagcacctcc acggtcggcc tcgcccgcaa tctcggggtg
    25741 gccttcggcg cgacggtctt cggctccctg ctcaacgccc gcctggccgt cgggtctgcg
    25801 cggctcctcc ccgccgacgt ggccgagcgc gtggtcggcg gcacgctgga acccggaagg
    25861 atcggcgagc tcggaccgcg gacggcctca gccgtggccg acgtctacag cgaggcgctc
    25921 tccaccgtct tcctctcagc ggtacccgtg ctgctgatcg ggctggtcct cgccctgatg
    25981 ctgaaagacg tgaagctgga ggcgcgcggc cagggcggac ccgggggcca gggtgccgag
    26041 cggccggccg caccgcggag gggctgagcg cgacgccggg ggacgccccc ggccggcggc
    26101 tccggcgctg ttcgagccgg cgtcgagccg ccggtgcgag cctgcccgta tgcaacctga
    26161 cgacgagggc gcgagggagt ggcggcgcgg gcccggcggg agtggccggt tcccctggcc
    26221 gctgcggctg agggcgcgtc acccgagacc ggcgccgccg cggatcgtgg gtgtggggat
    26281 cgacgtggcg gcgatagcca ggttcgggct ggccctggag cgcagccccg ggctgaggga
    26341 ccgcctgttc actccggagg agcagatgct gccttcgggg tcgccccgga cgacggcttc
    26401 cctggccgcg cgattcgccg ccaaggaggc cgtcgccaag gtgctcggtg cgccgggcgg
    26461 gctccgctgg cacgacgtgg gggtgcggac cggcgcccgc ggccggcccg tcctccaggt
    26521 gtgcggcacg gtcgcggccg ccgccgcccg gcaggggatc tcggtctggc acctgtcgct
    26581 cacccatgac ggtgacgtcg cctccgccgt cgtcgtcggt gcggcctgac gggggaaccg
    26641 ggcaggggcc gccgggcgaa gtccgaccgc cttccagccg ttcaccagcg tccctcgagt
    26701 cggcgcgggc accgtgggcg gcacggggga cacgcccatc ggcctggtgc gttcccccgg
    26761 cggcgggcgg ggcggagcgt cctcccccgt ggcgccacgc ctccccgccg cgtgccgggc
    26821 ggtcgccgcg attgacatag gtatggccgc atacctattt tgggctccgt ggagagaacg
    26881 acacatacgg cgggcggcga cacggcagcg cggaaggcga gccctgccct gccctccggc
    26941 tcgctcgccc aggacctcgc cctcgtcctc cccgccctcc accgcgccct ggaccgccgc
    27001 gtggacgccg acttcccgca ccccaagccc gccgagggcc agatcgccct gatgcggctg
    27061 atccgggacc gggagggcgt caccgtccgg gaggcggccg aggtgctgct ggtcaagccc
    27121 aacaacctca gcgcgacggt gacccagatg gtggccgcgg ggctggtcga gcgccgccgg
    27181 gacccggacg acaagcgcgt cacccacctc cacctcaccc cgaccgcagc cgaacgcacg
    27241 cacgccgtcg acgagttgat cggcgggtac gtcgagcagg ccctggccgg cctcagcgac
    27301 ggcgagcggg gcgcactcgg cgccgccgtc ggagccctgc acctgctgga gcgcggcctc
    27361 cacccgtcgt ccgcctcctg accccgcgcc accggccccg tacggccatc cgtctctctc
    27421 ccccccgtta tgtttttcgt ggtcctgcaa cggggccgct ggcctccggg cccggtatga
    27481 ctgttgcccc ctgtcgaacg tgatgacctg gggggtggtg tcgccagggt ccgggggtgt
    27541 tcgtcggaga cgctgatcag aggtccggcc accgcctggt ccggcgcaat gccggacggt
    27601 tcgcgggcgg caggtctgca taacgtggat gcgcgagcac gacacccaag ccgaggccgg
    27661 caccgtcaac atccccggaa agggcgcgat gttcgagatc gaagacgtgg gcgtgttcct
    27721 cggcctggac gtcggcaaaa ccgctcacca cggccacgga ctcaccccgg ccgggaagaa
    27781 aatcttcgac aaaccgctac ccaacagcga gccgaaactg cgggccgtct tcgacaagct
    27841 gaccgagaag ttcggcaccg tcctggtcat cgtggaccag cccgcctcca tcggcgccct
    27901 cccgctgacc gtcgcccgcg acgccggctg ccgcgtcgcc tacctgcccg gcctggccat
    27961 gcgccgcatc gccgacctct accccggcga ggccaagacc gacgccaaag acgccgccgt
    28021 catcgccgac gccgcacgga ccatgccgca caccctgcgc tgcctggaac tcaccgacga
    28081 gatcaccgcc gaactcaccg tgctgaccgg cttcgaccag gacctcgccg ccgaagccac
    28141 ccgcacctcc aaccggatac gcggcctgct cacccagttc caccccagcc tcgaacgcgt
    28201 cctgggcccc cgcctggacc accaggccgt cacctggctc ctggaacgtc acggctcccc
    28261 ggccgccctg cgcaaggctg gccgccgccg gctcgtcgaa ctgatccgcc ccaaggcccc
    28321 gcgcatggca cagcgcctaa tcgacgacgt cttcgacgcc ctcgacgagc agaccgtcgt
    28381 cgtccccggc accggcaccc tcgacaccgt cgtgccctcc ctggccgctt cgctggcctc
    28441 cgtccacacc cagcgccgtg ccatggaagc ccagatcaac accctgctgg aggcccaccc
    28501 tctttccccg gtcctgacgt cgatgcccgg cgtcggcgtc aggaccgccg cagtcctact
    28561 ggtcaccgta ggcgacggca ccagcttccc caccgccgcc cacctcgcct cctacgccgg
    28621 cctcgccccg accacgaagt cgtccgggac ctcgatccac ggcgaacacg caccccgagg
    28681 cggaaaccgg cagctcaaac gcgccatgtt cctctccgcc ttcgcctgca tgaacgccga
    28741 ccccgcctcc cgcacctact acgaccgcca gcgagcccgc ggcaaaaccc acacccaagc
    28801 cctcctccgc ctcgctcgcc aacgcatcag cgtcctgttc gccatgctcc gcgacggcac
    28861 cttctacgaa ccccggacac cgaaaaacgt cgagctcgcc gcataacccc agcaaccccg
    28921 aaccacccca aacccgacag ggatgccttg acgaaagaca tagaggcacc ccccgcgagg
    28981 aacacccatg tccacccgga cccccgaagc cccgcccgaa ccggcacccg cacccccgtc
    29041 gtccacccgg cgcggcaacc cctggctgac cctcatagcc gtcgccttcg ggctcttcat
    29101 ggtggcactg gacggctcgg tcgtctccat ggccaacccg gagatcggcc gcgacctgaa
    29161 cgccggcacc gccgacctcc agtgggtcac caactcctac ctgctggcgc tcgccgccgc
    29221 cctcatcctc ggcggcaaac tcggcgaccg cttcggccgc cgtacgtact acctgatcgg
    29281 cgtcgccggc ttcaccctcg cctcggtcgc catcgggctg gccgggtcga tcgagggcgt
    29341 catcgccttc cgcgccgtcc agggcttctt cggcgcgctg ctgatgccga acacgctcgg
    29401 gctgctgcgc gcggtcttcc cgccgaagaa gttcggcatg gcggtgggca tctgggcgat
    29461 ggtctcctcg gtgtcgacgg cgctgggtcc gatcgtcggc ggcctgctgg tcgagcacgt
    29521 caactgggag tccgtcttct tcatcaacgc ccccgtgggc gtcctcgccc tcgccttcag
    29581 cgcctgggtg ctgccgcagg ccaagggcga ggaggggcgc gggacgcggt tcgacatccc
    29641 cggggtggtg ctgctcgccc tcgggctgct gctcgtcgtc ttcgccgtcg tcaagggcga
    29701 gacgtggggc tgggcctcgc cggccaccgt gctgaccctg ctcgccggcc tcgcggtcct
    29761 ggtcgccttc ggcctctacg agaaccgggt cgcccacccg ctgctgccga tgcgcctctt
    29821 ccgcaacccg gcgctgaccg tcggcaccgt catcaccgcc gtcaacttct tcgtcctgct
    29881 cggcgtgatc ttcttcgtca tgctgtacct gcagaacgtg cgcggctaca gccccgtcga
    29941 gtccggcgta cgcaccctcc cgctcagcct cgcctcggtc gtcgccgccc cgctcggcgc
    30001 cgccctcacc ggccgcttcg gcgcccgcct gacgatgccg ctcggcatgc tcctccaggc
    30061 cggcgcctcc ctcggcatcc tcggctgggg cctggacacc gcctacgccg tgctctggcc
    30121 gcccttcgtg gcgctcggcc tcggcatcgg catggtcatg gccgcctcct cggacgccat
    30181 cgtgggcaac gcgcccgtgc gggacgcggg ggtcgcgggc ggcctccagt ccaccgccct
    30241 ccaggtcggc ggcgccctgg gcacctccgt cctcatctcc ctgatcagca gccgggtctc
    30301 cgcgaccttc ggccccgaac tggcctccgc cggcgtcccg gccccggtcg ccgacggcct
    30361 cgccgaggcc aaggacgccg tcgccatggg cgtggccccg gtaggccccc gcctccccga
    30421 atccctccac ggccccgtca cggaggcggc cggccaggct ttcctcaacg gcgtccacgc
    30481 cgccgcctgg gtcacggcct gcctgtgcgt ggcgggggcg gtggcttcgg ggtgggtgct
    30541 gcggcggccg acgtccggcg cctgaggcca cctcaagccc ggccggcgct tgaggccagg
    30601 agcctgaccg gcgcttgagg tcaccccacc aggaaccccg cagcagtagc cacccccgcc
    30661 gccgtccccg cgcacacctg ccccaccgtg tggtacccca gcgccacccg cgaccagcac
    30721 accgcccccg ccagcgcgta ggcggcgagc cacgccggat ggtgcaccac ggccagctgg
    30781 gccaccacgg ccgaggcgac ggcggcgtcg acggagatct tccagacggt gttgacggcg
    30841 agcaggacga tggtcatggc ccagagggcc agcatggtga cgaggatgtc gcggggggcg
    30901 ttcccggcca ccatgaccag ggaaccggcg ccgatggagc cgaggatgac gaagaagatc
    30961 ggcgcgcgct tggtgcggtc gaccacgtgg cggtcgcccc aggcgccgcg tccgcgctgc
    31021 cattcgatgt atccggcggg tatgaggccg gcgcagagtg ccccgaggaa cccccagagg
    31081 aggccggacc agtgtccgcc ggccgccgcg aggccgatgc cgagcatccc gccgaggagg
    31141 acgttgcggg gctggaggac gtcggtgacg cggcgggcgg tgaggttctc cggcgtgccg
    31201 ggctcggtgg gggcggtgct ggtggtcatc gggtcggctg ctccggggag ttcgtggtgg
    31261 cggcggcctc gcccgcgcgg gcggcggcga ggacggcggt ggtgcgggcg gcggggatgg
    31321 tgcggcaggc ggcggcgacc cggacgagcc aggcgacctc gccctcctgg tcctcggcct
    31381 gccgtgggtc ggtggcgggg gcggcgggcc cggcgggtac gccctcggcg tgggcgacga
    31441 gggcggcccg tatccagtgg gcgtcggtgc gcgggccccg ctcgtcgggg tcggcggtgt
    31501 cctcggcggc ggcggtgcgg gcggcgtcgg ccaggtgccc gggcgcgtag tggcgcagct
    31561 tctcgacggc gtcggcgatg tcggcggacc agcggtcgac gcgcaggtcg gccggggtgt
    31621 cgaagcgggt gacctcgcgc agcagggagg cgggcggggc gaagggctgc tcggggaagg
    31681 cggtcatcag ctcgcgccag agcgggtgca gccgggcctg ggcgcgccag aggcgggcgc
    31741 ggcgcaggcc ggtggagaag gcgggcagcg aggcgccgac ggcgaacagg acgaagagca
    31801 ggacctgtcc ggcctcggtg accttgtcga aggtgtcggc gaactccacg ctcggctggt
    31861 cgacgacgct gatccacatg aacagggtgc ggctggcggt gtaggcgacg ccgatgaaca
    31921 tggcggcggt catcatcgac aggccgacgc gcaggtggcg ggcggtggcg tcggcggtgg
    31981 ccagcttcca ctggtaggcg cagacggcac tggcggcgcc gaggtagacg tagaagaccg
    32041 tcatgtagag ggtggcgccg ggctggcccg cgtggtcgga gacgaagcgg tcggagggga
    32101 ccgagcggtc gacgacggtg aagaagagga cggtcagcag gatgagggtg gcgaccgacg
    32161 ccttggcggc gacgcgctgc acgaggcggg cgaagcggac gtggcggggg acggcgcccc
    32221 ggtccgggta gcggccgtag atggcgacga tgtagctgag gatggcgagg atcgcgatgg
    32281 tcgccgtgta gtgcttgatg aggacggcga ggtcggtgac cgggctgtcg ttgagcgtgg
    32341 tgcggacgaa ctcggtcttg gtccacaggg cggcggcgaa tccggcgtag cagccccaca
    32401 gggcgcgtct gcggcggtcc tcctcgtccc cccagagggc cgccggcatc cgccacaggg
    32461 cgacggccgt catcagcacg gcgacgaggt aaccggccag atcgagggta ctcacacagg
    32521 gtccttgggt ggggggtcgc tcggcccggc gggggaccgg gcggtggggg ccgtccgagg
    32581 ttagtgcgtc agggcctccg ccggaacagg gaacgggccc cgcgccggtg ggagacgggc
    32641 cgggcaaggg agttggcgag gcggcccatc atgtcgtcgc ccgccacgtc gcgggccatg
    32701 cgcgggatga gggaggcgcc gaactccgcg acccgctcgt cgtgggtgtc gtagacggcg
    32761 cgggcctgca cgggtccgtc gaggccgggg agggggccgt cgtcgggggc gggaggcccg
    32821 gcgtccggcg ggcggcccag gacgcggccg atcaggctgg cgtcgaagac ggggaggagg
    32881 cggcggagct ggtcgccgtc gaggctggtg ccgtggtcga accactcgtg gcacagctcg
    32941 tgcaggatga cgtgctgcgt ctggtaggcg gtggggcgtc tgcggtacag gacgaagctg
    33001 gtggcggggg tcttcagccg cagcccgcag gcggagtgga cgcgcgtgag gtggtcgggg
    33061 atcc
//
