LOCUS       Naphthocyclinone            14040 bp	DNA     linear     24-May-2013
DEFINITION  Naphthocyclinone biosynthesis cluster
ACCESSION   Naphthocyclinone
VERSION
KEYWORDS
SOURCE      Streptomyces arenae
FEATURES             Location/Qualifiers
     source          1..14040
                     /organism="Streptomyces arenae"
                     /mol_type="genomic DNA"
                     /strain_name="DSM 40737"
                     /db_xref="taxon:29301"
     CDS             complement(1071..1679)
                     /locus_tag="Naphcy_00050"
                     /product="putative LuxR family transcriptional regulator"
                     /note="original product:regulator"
                     /note="original gene:ncnR"
                     /note="category:4.1 transcriptional regulator"
                     /transl_table=11
                     /inferenece="InterPro:IPR011006"
                     /inferenece="InterPro:IPR000792"
                     /inferenece="InterPro:IPR001789"
                     /inferenece="InterPro:IPR011991"
                     /inferenece="InterPro:IPR016032"
                     /translation="MIRVLLAEDMGMVRGALVALMEMEQDLSVVAQVADGREVLSAGL
                     AHRPDVAVIDVGLPGVDGIEAAAQLHEHLPECRTLMLTGTDQPGTVRRAMDARVFGYL
                     LKDAPPSELAAAIRKVADGQRVIDTRLAFTVWQRGDHPLTERESDVLSLASEGAEASE
                     IAAQLHLAVGTVRNYLSSAVTKLGARNRLDAVRIARDAGWIG"
     CDS             2030..2962
                     /locus_tag="Naphcy_00060"
                     /product="cyclase/dehydratase"
                     /note="original product:cyclase"
                     /note="original gene:ncnE"
                     /note="category:3.4 other modification"
                     /transl_table=11
                     /inferenece="InterPro:IPR001279"
                     /translation="MTDERRQDRTAPDDAWLEEVADGVFAYVQPDGGWCLNNAGLVVS
                     DGRAALVDTAATETRARRLREAVRGVTAAPPGVLVNTHFHGDHTFGNFVFPEALVVGH
                     ERTRSEALAAGLHLTGLWPDVRWGALELAPPALTYRDGVTLHVGDVRVEVLHPGPAHT
                     TDDSVVWLPEQRVLFTGDIVMPGVTPFCAMGSVSGSLAVLDRLRALGARTVVPGHGPV
                     AGPEVFDATESYLRWVRATARRGLADRLTPMQVARACDLGEFAGLRDSERLLPNLRRA
                     YAEEQGAAPGAPLDIGELFAEMIEFHGRLPTCRA"
     CDS             3984..4553
                     /locus_tag="Naphcy_00070"
                     /product="putative oxidoreductase"
                     /note="original product:Ncn-orf3"
                     /note="category:5.1 general function"
                     /transl_table=11
                     /inferenece="InterPro:IPR011251"
                     /translation="MPVYLAAVGPRSLRLAGEIADGWLGVFTPPDAVAKAVTEIRAGR
                     ESGRAGPDRLRGPAQPAGVGRGRRAHRGDALRGQYVYLLGIGDPAHNFYCALAREMGY
                     AEEIEVFLGRLADGDRAGAAAALPLDFIDRTSLAGPVPRLADRMRAYAEAGVTTLGVM
                     VSAAATTLDGRLGILHAAAEALKASGVAD"
     CDS             4698..5561
                     /locus_tag="Naphcy_00080"
                     /product="hypothetical protein"
                     /note="original product:Ncn-orf2"
                     /note="category:5.4 hypothetical protein"
                     /transl_table=11
     CDS             complement(5668..6885)
                     /locus_tag="Naphcy_00090"
                     /note="original product:hydroxylase NcnH"
                     /note="product synonym:putative FMNH2-dependent
                     monooxygenase"
                     /note="original gene:ncnH"
                     /note="category:3.3 modification reduction"
                     /transl_table=11
                     /inferenece="InterPro:IPR013107"
                     /inferenece="InterPro:IPR009075"
                     /inferenece="InterPro:IPR009100"
                     /inferenece="InterPro:IPR006091"
                     /inferenece="InterPro:IPR013786"
                     /inferenece="InterPro:IPR006092"
                     /translation="MPDDAQTRPTLTPTAPALTADPTAPAIPVGPVALVQRARDLAEL
                     AGKHAGDADRERRLHPDVVRAVAEAGFGRHFVPVRWGGADGTFADLLAAVARVGEGCT
                     SAAWVAALAATVPRMAAHLPRQGQAEVWSDGPDTLLVGALMPLGRAERAAGGWRLTGT
                     WSYVSGVDFSDWALVCARTAEDGVEVPRYFALPREAYAIRDTWFTVGMRGTGSNTLSV
                     DDVYVPDHRVCTRAAVLDGDCPDAPADCTRVPLKAVNGLSFAAPVLGAAKGLLAEWTR
                     WAAPRITGTGDGDPRLAENALRHGVLARAAGEVDGAELLLDRTARAADTGALDPLLTA
                     RGGRDCALAAELLLTAADRLFRAAGTSAQVEGSPFERGWRDVSAAVSHLVLRFEPAAT
                     AYAQAVLTAQQEP"
     CDS             complement(11340..12605)
                     /locus_tag="Naphcy_00010"
                     /product="polyketide synthase beta-ketoacyl synthase
                     subunit"
                     /note="original product:beta-ketoacyl synthase/acyl
                     transferase"
                     /note="original gene:ncnA"
                     /note="category:1.1 PKS"
                     /transl_table=11
                     /inferenece="InterPro:IPR014030"
                     /inferenece="InterPro:IPR014031"
                     /inferenece="InterPro:IPR016038"
                     /inferenece="InterPro:IPR018201"
                     /inferenece="InterPro:IPR016039"
                     /translation="MTRRVVITGIGVRTPGGLGTKAFWSLLSEGRTATRRISRFDPSP
                     FRSRIAGEVDFDAEAEGFSPREVRRMDRATQFAVACTRDAVADSGLETTALDPARVGV
                     SLGSAVASATSLEREYLVLSDSGRQWLVDDGFLSPHMADYLSPGVMPAEVAWSVGAEG
                     PVTMVSDGCTSGLDAVGHGVQLIREGTVDVVLAGASDTPVSPIVVACFDAIKATTPRN
                     DDPEHASRPFDGSRNGFVLAEGAAMFVLEEYEAARARGAQIYAEVGGFATRCNAYHMT
                     GLKTDGREMAEAIRAALDEARLDRTAVDYVNAHGSGTKQNDRHETAALKRSLGAHAYD
                     VPVSSIKSMVGHSLGAIGSIEIAACALAIKTNVVPPTANLHTPDPECDLDYVPLTARD
                     KQVDTVLSVGSGFGGFQSAMVLHRPEVAA"
     CDS             complement(10054..11343)
                     /locus_tag="Naphcy_00020"
                     /product="polyketide synthase chain length factor subunit"
                     /note="original product:chain length factor"
                     /note="original gene:ncnB"
                     /note="category:1.1 PKS"
                     /transl_table=11
                     /inferenece="InterPro:IPR014030"
                     /inferenece="InterPro:IPR014031"
                     /inferenece="InterPro:IPR016038"
                     /inferenece="InterPro:IPR016039"
                     /translation="MNSGTRSGTSSATRNGTSSGAAGAGAVVVTGVSVVAPGGLGTEE
                     YWKSVLTGRSGIGELTRFDVTRYPARLAGQIRDFEAADHLPSRSLPQTDVSTCHALAA
                     AAWALADAGVGAGTLPDYDMGVVTSTSQGGFEFTHREFNKLWSKGPQHVSVYESFAWF
                     YAVNTGQISIRHGMRGPSAALVAEQAGGLDAVGHARRTVRRGTRLVLSGGVDSAFDPW
                     GWVAQSASGRVTTATDPERAYLPFDTDASGHVPAEGGAILVVEDAASARLRGAERIYG
                     TLAGYASTFDPRPGSGRPPGLRRAAELALADAGLAPGDIDVVFADAAGVPELDRAEAA
                     AISGLFGPNAVPVTAPKSVTGRMYAGGGPADLVAALLAVRDGVVPATAHTTSVPAGYG
                     IDLVLGEPRALPVRAALVLARGRWGFNSAVVVTGPTH"
     CDS             complement(9749..10009)
                     /locus_tag="Naphcy_00030"
                     /product="polyketide synthase acyl carrier protein
                     subunit"
                     /note="original product:acyl carrier protein"
                     /note="original gene:ncnC"
                     /note="category:1.1 PKS"
                     /transl_table=11
                     /inferenece="InterPro:IPR006162"
                     /inferenece="InterPro:IPR009081"
                     /translation="MAHIQIDDLRRILVACAGEDDGIDLSGDILDTSFGDLGYDSLAL
                     METAARIERDYGVALADDVIADARTPRDLLDLVNRAVPADAR"
     CDS             complement(8805..9752)
                     /locus_tag="Naphcy_00040"
                     /product="cyclase/dehydratase"
                     /note="original product:aromatase"
                     /note="original gene:ncnD"
                     /note="category:3.4 other modification"
                     /transl_table=11
                     /inferenece="InterPro:IPR019587"
                     /inferenece="InterPro:IPR005031"
                     /inferenece="InterPro:IPR023393"
                     /translation="MTAGPRPLHAEHTRVVHAPPGPLYDLVADVTLWPAVFGPTVHAR
                     RLEGGPDSERIRLWATVNGRVSDWVSRRTLDPGRFTVGFEQEVSSAPVASMGGEWLFR
                     ELGGGRTEVVLRHHFTVVDDDPAAVSWVQEALDRNSAAELGALARVVETGHPPREIVF
                     SFTDTLALTGPAESAYEFVARADLWPERLPHVAGVTLTETAPGVQDLRMETATADGST
                     HTTHSVRVCRRPEWIAYKQLRTPELLLGHSGLWTFGEGPDGPFATASHTVALNPEAVS
                     RVLGADRTTADARRHVRELLGRNSRTTLAHAAGQEAPAR"
ORIGIN      
        1 ggatccaatg cagcgtggct tttatgatcg ccctcaatct gctggcctcg catcccaggc
       61 cagcgcaaat cgtcggtttt ctgatcactc tgccgctggt cggcctggtt caggtcatac
      121 attgcgcccc caccgcgcag gggttacggg agcgctacgg aaagtttacc ctgatattgc
      181 aggccctcct gacgtttata ccaccggtgt ttttaggcct taattgggtg ggtctcgccg
      241 gtcttctggc cggggcaata ctgctggttc tcgacccgcc cctgtccata gggctattcg
      301 gtgcggtgtg tgccgcggcc agcaccgtcg ccgtcctctt cggaagtcga attttcggcg
      361 tttcctggct ggttgtttcg atattgatga tcggcacgat gatctacggc ctcggtcgcg
      421 tcgccgaact catggccgag ttgcaccgga cccgtggcgt gtcgacccgg ctggccatcg
      481 agcgggaacg gctgcggatg gcgcgggacc tgcacgacct gctcggctac agcctgtccg
      541 ccatcaccct caagagcgag ctgaccatcc ggctggtggg atcgagcgac gagcgggccc
      601 gggccgaact cctggagatc ctccaggtct cacgccaggc actcgccgac gtgcgctcgg
      661 tgtcccacgg ctaccggacc atgcggatcg ccgacgagac cacctcggtg cggggtgtgc
      721 tgctcgcggc gggcatcgag gtgtccacgg acatgtccgt gcgcggcctc cccgtcgaga
      781 aggagacggt cctggccacg gtgctgcggg agagcgtgac caacctgctg aggcacagcc
      841 gcgccgatca ctgccgcatc gtcctgcggg aggagggcag ccgggtccgc ctcaccgtct
      901 ccaacaacgg cgtggtcccg ggctccgcgc tgaaccggct gggcggcgga ctcgacaacc
      961 tcaccgagcg gctgacccgg gtgggcggcc ggctcggcgc gaccgtcgac ccggacggct
     1021 ggttccacct ggtcgccgac tgtccggccg gaccacggca cggcgcgggc tcagccgatc
     1081 cagccggcgt cccgggcgat ccgcaccgcg tcgagacggt tgcgggcgcc cagcttggtc
     1141 accgccgaac tcaggtagtt ccggacggta ccgacggcca ggtgaagctg ggcggcgatc
     1201 tccgaggcct cagccccttc cgacgccagt gacaggacgt cggactcccg ctcggtcagc
     1261 ggatggtcgc cgcgctgcca tacggtgaag gccagccggg tgtcgatcac ccgctggccg
     1321 tccgccacct tgcggatcgc cgcggccagc tccgacggcg gggcgtcctt gagcaggtag
     1381 ccgaagaccc tggcgtccat cgcccggcgc acggtgcccg gctggtccgt gccggtgagc
     1441 atcagggtcc ggcactccgg caggtgctcg tgcaactggg ccgcggcctc gatgccgtcc
     1501 accccgggaa gtcccacgtc gatcacggcg acgtctgggc ggtgcgccag cccggcggag
     1561 aggacctcgc gcccgtcggc cacctgcgcc acgacactga gatcctgctc catctccatc
     1621 agcgccacca gcgcccctcg caccatcccc atgtcctcgg cgagcaagac gcgaatcacc
     1681 cgagcctccc cgtttcccta cagccttgat gctcccgttg tcactcagtg tccgtggcat
     1741 ccgtcgggcg gcacaatagg gcccgccgcc ggaccgacgg gcaactcgcc gcaggaaagc
     1801 gcgtgttggg ctcacggcat cgagtgccgg gggcccgtcg gcggtgtccg gggttcgagt
     1861 cgtactcgac ccgctgcggc aagggtcgta tcccaaccgg acccgcgacg accgcggcag
     1921 ccctcgggag aaccctgtga cgacaccgcg cacgacgaca ccgcgcacga cgacaccgcg
     1981 cacgacgaca ccgcgcacga cgacaccgcg aactaaggcc accggagcgg tgaccgacga
     2041 acggcggcag gaccgcacgg ccccggacga cgcgtggctg gaggaggtgg cggacggcgt
     2101 cttcgcctac gtccagccgg acggcggctg gtgcctgaac aacgccggtc tcgtcgtgtc
     2161 cgacggccgg gcggcgctcg tcgacaccgc cgcgaccgag acccgggccc gccgcctgcg
     2221 ggaggccgtg cgcggggtga cggcggcacc ccccggcgtc ctggtcaaca cccacttcca
     2281 cggcgaccac accttcggca acttcgtctt ccccgaagcg ctggtcgtcg gccacgaacg
     2341 gacccgcagc gaggcgctgg cggccggcct gcacctcacc ggcctgtggc ccgacgtgcg
     2401 ctggggcgcc ctcgaactgg cgcccccggc cctcacctac cgcgacgggg tgaccctgca
     2461 cgtgggagac gtgcgcgtcg aggtgctgca cccgggcccg gcgcacacga cggacgactc
     2521 ggtcgtctgg ctgcccgagc agagggtgct gttcaccggg gacatcgtca tgccgggcgt
     2581 cacgccgttc tgcgcgatgg gatcggtcag cggatccctc gccgtcctcg accggctgcg
     2641 cgcactgggc gcccgtaccg tggtgccggg ccacggcccg gtcgcgggcc ccgaggtgtt
     2701 cgacgccacc gagagctacc tgcggtgggt ccgggcgacg gcacggcgcg gcctggccga
     2761 ccggctcacc cccatgcagg tcgcccgcgc ctgcgacctg ggcgagttcg ccgggctccg
     2821 cgactccgaa cggctactgc cgaacctgcg ccgcgcctac gcggaggagc agggtgcggc
     2881 ccccggggcg ccgctggaca taggggagct gttcgccgag atgatcgagt ttcacggccg
     2941 gctgccgacc tgccgggcct gaggcgtcca cacctcgaac tgNNNNNNNN NNNNNNNNNN
     3001 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     3061 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     3121 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     3181 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     3241 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     3301 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     3361 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     3421 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     3481 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     3541 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     3601 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     3661 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     3721 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     3781 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     3841 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     3901 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     3961 NNNNNNNNNN NNNNNNNNNN NNNggatccc ggtctacctg gcggcggtgg ggccccgcag
     4021 cctgcggctc gcgggcgaga tcgcggacgg ctggctcggg gtgttcaccc cgcccgacgc
     4081 ggtcgccaag gccgtcaccg agatccgggc gggccgggag agcggccggg cgggacctga
     4141 ccggcttcga ggtcctgccc agcctgccgg cgtcggtcgc ggacgacgtg cccaccgcgg
     4201 tgacgcgttg cgcggccagt acgtctacct gctgggcatc ggcgaccccg cgcacaactt
     4261 ctactgcgcg ctggcccgcg agatgggcta cgccgaggag atcgaggtct tcctcgggcg
     4321 gctggccgac ggcgaccggg ccggtgcggc ggccgcgctg ccgctggact tcatcgaccg
     4381 cacctcgctc gcgggaccgg tgccccggct cgccgaccgg atgcgggcgt acgcggaggc
     4441 cggcgtgacc accctcgggg tcatggtgtc ggcggcggcg acgaccctgg acggccgact
     4501 gggcatcctg cacgcggcgg ccgaggccct gaaggcatcg ggggtcgccg actgaggccc
     4561 ccaccgccac ccgcacagac accgacgcgg cgcgggtctg ccagtacggc cggggtctgc
     4621 cgtgggtggg tggctgggtg ggaagcgggg gtcggtaatc ggacagtgcc cgggaggggc
     4681 gtggggagtg ggaggcgcgg tgacgtacac acgacatgcc agtgatacgg gattccggcg
     4741 gacgggcggg aggagccggt gttcgccgac gagttccggc tcccggatgc cggcctggca
     4801 gccggacggg ctgcccccgg gatggctggc ccgtcccgcc gccgggctgc ccgccggtga
     4861 cgggaccgcc cgcgtcaccc cggagggcct ggtggtggca cccccgggca cggacccggc
     4921 ccacccgcga accccggttc gccgtcccgc cccgtcggcg ccgctgggcc acctgcgctg
     4981 ggccgccttc gccggcaccg ccaccccacc cggcttcacc ctgcccgaca ccggactcct
     5041 caccgcccac atggagctgg ccgccgaggt gtacggcccg ggtgcggacc gtccgaccgc
     5101 ggccggcatc gccgacaccc ggcacgggat gggcgggatg ctctgtgtgg atctggggtc
     5161 cgggctggtg ctcgacttcc tgctgaccaa tgaccgggtc tgggtgctgt acgagcggct
     5221 cggccggccc ggcgccggtc acggcacgtt cacgtacgag gtcccggtcg ccgagcggtc
     5281 gcctggccgt cggcaccggt gtgcgatacg cgtcgaccgg gcccgcggca ccgcggtgtg
     5341 gctgctggac ggcacggagg tgttcgccgt gccggacctc ggccgtcgcc tcccgtcccg
     5401 cgccgcccac atcacccgct ccgccgacgg ccccgaggag agcgtccggc ccggccggct
     5461 cgccctcggc atcggcctgt tcggcgaact cgcggaaggg tccggggtac gcctcacggt
     5521 ccgccgggcc accgtgacac gctccacccc cggcacgtcg tagagacccc ggccggacac
     5581 cacacggccc gccctcctcc cggatcaccg gtaaggaggg cgggctcagt gtcgtacccc
     5641 cgcccagagc tcctgctcag ggctcctgct cagggctcct gctgggccgt cagtaccgcc
     5701 tgggcgtagg ccgtcgccgc cggttcgaag cgcagcacca gatggctcac cgccgcgctg
     5761 acatcacgcc agccgcgttc gaacgggctc ccctcgacct gcgcggacgt gcccgcggcc
     5821 cggaacagcc ggtccgccgc ggtcagcagc agctccgcgg cgagcgcgca gtcccggccg
     5881 ccgcgcgcgg tcagcagcgg gtcgagcgcc cccgtgtcgg ccgcccgggc ggtacggtcc
     5941 agcagcagtt cggcgccgtc cacctccccg gcggcgcggg ccagcacccc gtgccgcagc
     6001 gcgttctccg cgagccgggg atcgccgtcg ccggtccccg tgatccgggg tgcggcccag
     6061 cgcgtccact ccgccagcag ccccttcgcg gcccccagga ccggtgccgc gaaggacagg
     6121 ccgttcaccg ctttcagcgg cacccgggtg cagtcggcgg gcgcgtccgg gcagtcgccg
     6181 tccagcacgg ccgcgcgggt gcacacccgg tggtccggga cgtacacgtc gtccacggag
     6241 agggtgttgc tgccggtgcc gcgcatcccg acggtgaacc aggtgtcccg gatcgcgtac
     6301 gcctcgcggg gcagcgcgaa gtaccgtggc acctcgacgc cgtcctccgc cgtccgcgcg
     6361 cacaccaggg cccagtcgga gaagtcgaca ccgctgacgt acgaccaggt gccggtcagc
     6421 cgccagccgc cggccgcccg ttccgcccgg ccgagcggca tcagggcgcc gacgagcagg
     6481 gtgtccgggc cgtcggacca gacctcggcc tgcccctggc ggggcagatg ggcggccatg
     6541 cgcggcacgg tggcggccag tgcggcgacc cacgcggcgg acgtgcagcc ctcgccgacg
     6601 cgggcgaccg cggccagcag gtcggcgaag gtgccgtcgg cgccgcccca gcggaccggc
     6661 acgaagtgcc gcccgaaccc cgcctccgcg accgcgcgca ccacgtcggg atggagccgc
     6721 cgctcccggt ccgcgtcacc ggcgtgcttg cccgccagct ccgcgagatc ccgagcccgc
     6781 tggacgaggg cgaccgggcc gaccgggatg gccggtgcgg tcgggtcggc cgtcagagcc
     6841 ggtgcggtcg gggtgagggt cggccgggtc tgtgcgtcgt cgggcatcag gcaccgtccc
     6901 cgccgcccgg caggaccgcc gggacgaggc cgcggcggct atcgcgaggc cgccgagcag
     6961 gctgacgttc ttgaagaact cgttgcgctg catacgccgt cgggccgggt ccgactggcg
     7021 ccagaaggcg tgcacggtca gggtcgtcgg caccaggcag gcgatcagcg cgccgccgcc
     7081 gagcaccggc gcgacaccgc tgcccagggc cagcccgccg acgaccatgc cggtggcggt
     7141 cgcccgggtg gcggcctccg gcagcggaat gccgtgctgc cgggccagtt cgggcagtgg
     7201 gccgggctcg cggagcacgc cgtagccgcc ggcgacgaag ctcgccgcca gcaggggccg
     7261 ggccagccgg ctgatgagct ggggtccttc aggcatgggc cgccttctcc ttagcgttcg
     7321 gcgattcgtc tcccgggtgg ccgggtggtt ccaggagggc aaggctcgcg acggcgtctc
     7381 gaagagcgct cgaagacggc tcgcacccgg cggcgcacct cgagtcggat tcgagcggcg
     7441 gtggtgacgc tggccgcgag ccgcgggacg taccggcgtt ccacggcgca gcaccggcta
     7501 tccgaggaga ccgcgatgac ggcagacgac aagcgatgga tccNNNNNNN NNNNNNNNNN
     7561 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     7621 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     7681 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     7741 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     7801 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     7861 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     7921 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     7981 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     8041 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     8101 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     8161 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     8221 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     8281 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     8341 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     8401 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     8461 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     8521 NNNNNNNNNN NNNNNNNNNN NNNNggatcc gcgcggccgg cgcagggcgc agggcgcgct
     8581 ggagacccag gtgctcgcgg cgctgcagca ggccgacgga ccggtgacgg cgggctgggt
     8641 gcgggagcgg ctggccgccg gctcgcctac acgaccgtga tgacggtact gggccgcctg
     8701 ctggcgaagg acgccgtcac ccgcagcgcg agggccggtc gttcgtgtgg ctgcccgccg
     8761 ccgaccaggg ggactcgccg cgctgaagat gcgccgggtg ctggacggcg agcgggaccg
     8821 gcgggcggtc ctggccagct tcgtcaccac gctgcccgag ggcgacgagc ggttgctgcg
     8881 ggaactgctg cggcacgcgg gcgacgggga ctgagcgcat ccgtgggcat cttcgtcttc
     8941 ctgccgctgg tgctgccgtt gacggcgtgg ccgatcgcgc gcctgggcga acagcgcctc
     9001 gatccccgta ccgccaccgt gctgctcacc acggtcgccg ccgtcatggc gctgtgcagc
     9061 acggtgtgcc tggcgctgct gatggtcgtc ggcaccgcgc agctccccgg caaccccctt
     9121 ccggacggct ggtcggaccc cgaggtgcgg gagagcgtgc cgcggcacgg ggtcgccggg
     9181 aaggcggcga tcccggcgct gctcgcggtc gtcaccggct gcgcgggcgc gctgctgcgg
     9241 caccgccggg tcaggagccg ggcgcaccgg gcgctgcggg gcctgccggg caccgaggtc
     9301 gcggtcctgc cggactcccg gccgtacgcc tacgcgttgc cgggcggccc gtaccgaccg
     9361 cgtcgtggtg tccacggcga tgctcgcctg cctcgcgtcc cgggagcggc gcgccctgtt
     9421 cgcccatgaa cgcgcccacc tgcgggcccg gcaccaccgc tacctgctgc tggccctgct
     9481 ggcggcccac gccaacccgt tcctgctgcc gctgcggacg gccgtcgcct gcacggtgga
     9541 acgctgggcg gacgaggagg cggcgcggac cgtgggcagc cgccgggcgg tcgcccgggc
     9601 gatcggcacg gcggccctcg tctcgcgggg cacccccgcg cccaccctgg ccggcctcgc
     9661 cggtcttgcc gcgccgggcc cgctgccgcg ccgggtcgcc gccctgctcg gcccgccgcc
     9721 cgcggtacac cgctggccgt cgccgttcac gaccgcgggg ctggcggtgt ggacggccac
     9781 caccggcacc ctgctctcgg ccatgttctc cgccaactcg gcgttcaccc tgctgctcct
     9841 cctgcacgcg gccacgcctc tcgcctaggt cccgcgcggc tccgcccccg atcctccttc
     9901 gagccaggct cgaggccccg gccgcagcct gctgaaggcc cgagtaacgg acctgatgcg
     9961 ctgcacgtac ggaggcgata tgactcggcg cgttgtgatc accggcatcg gggtgcgtac
    10021 cccgggcggc ctgggaacga aggcgttctg gtcgctgctc agcgaggggc ggacggccac
    10081 ccggaggatc tcccgtttcg acccctcccc cttcaggtcc cggatcgcgg gcgaggtgga
    10141 cttcgacgcg gaggcggagg ggttcagccc gcgcgaggtg cgcaggatgg accgcgcgac
    10201 ccagttcgcc gtcgcctgca cccgggacgc ggtcgccgac agcggactgg agaccaccgc
    10261 tctggacccg gcccgcgtcg gcgtgagcct gggcagcgcg gtggcgtccg cgaccagcct
    10321 ggagcgggag tacctggtgc tgtccgacag cggccggcag tggctggtgg acgacggttt
    10381 cctctccccg cacatggccg actacctcag tccgggggtg atgccggccg aggtggcctg
    10441 gagcgtgggc gccgagggcc cggtgacgat ggtctccgac ggctgcacct ccggcctgga
    10501 cgcggtcggg cacggcgtcc agctgatccg ggagggaacc gtcgacgtcg tcctcgcggg
    10561 cgcgtccgac accccggtct cgccgatcgt cgtcgcctgc ttcgacgcca tcaaggcgac
    10621 cacaccccgc aacgacgacc cggagcacgc ctcccggccg ttcgacggct cgcgcaacgg
    10681 cttcgtcctg gcggagggcg ccgcgatgtt cgtcctcgag gagtacgagg cggcccgggc
    10741 ccgcggcgcg cagatctacg ccgaggtcgg cgggttcgcg acccgctgca acgcctacca
    10801 catgaccggt ctgaagacgg acggccggga gatggccgag gcgatccggg cggcgctcga
    10861 cgaggcccgc ctcgaccgga ccgccgtcga ctacgtcaac gcgcacggct ccggcaccaa
    10921 gcagaacgac cgccacgaga ccgccgcgct caagcgcagc ctgggcgcgc acgcctacga
    10981 cgtgccggtc agctccatca agtcgatggt cgggcactcg ctgggcgcca tcgggtccat
    11041 cgagatcgcc gcctgcgcgc tcgccatcaa aaccaacgtc gtaccgccca ccgccaatct
    11101 gcacaccccc gaccccgagt gcgacctgga ctacgtgccg ctgaccgccc gcgacaagca
    11161 ggtggacacc gtgctgtcgg tcggcagcgg gttcggcggg ttccagagcg cgatggtgct
    11221 gcaccggccg gaggtcgccg catgaacagc ggtacgagga gcggtacgag cagcgctacg
    11281 aggaacggta cgagcagcgg cgcggccggt gccggtgccg tggtcgtcac cggtgtctcg
    11341 gtggtggcgc cgggcggtct ggggaccgag gagtactgga agtccgtgct caccgggcgc
    11401 agcggcatcg gggagctcac ccggttcgac gtcacgcgct acccggcccg gctcgccggg
    11461 cagatcaggg acttcgaggc ggccgaccac ctgcccagcc ggtcgctgcc gcagacggac
    11521 gtctcgacct gccacgcgct ggccgccgcg gcctgggcgc tggccgacgc cggggtgggc
    11581 gccgggacac tgcccgacta cgacatgggc gtggtcacct ccacctcgca gggcgggttc
    11641 gagttcaccc accgggagtt caacaagctc tggagcaagg gcccgcagca cgtcagcgtc
    11701 tacgagtcgt tcgcctggtt ctacgccgtg aacaccgggc agatctccat ccggcacggc
    11761 atgcgcggcc cgagcgccgc gctcgtcgcg gagcaggcgg gcggcctgga cgcggtgggg
    11821 cacgcccgcc gtaccgtgcg ccggggcacc cggctggtgc tgagcggcgg ggtggactcc
    11881 gcgttcgatc cgtggggctg ggtggcgcag tcggcgagcg gccgggtcac cacggcgacc
    11941 gacccggagc gcgcgtacct gcccttcgac accgacgcgt ccgggcacgt gcccgccgag
    12001 ggcggcgcga tcctggtcgt cgaggacgcc gcctcggccc ggctgcgcgg cgcggagcgg
    12061 atctacggga cgctcgccgg atacgcgtcc accttcgacc cgcggcccgg ttcgggacgc
    12121 ccgccaggcc tgcgccgcgc ggccgaactg gcgctggccg acgcggggtt ggcgcctggc
    12181 gacatcgacg tggtgttcgc cgacgcggcc ggcgtgccgg aactcgaccg ggccgaggcg
    12241 gcggccatca gcggcctgtt cgggccgaac gccgtcccgg tgaccgcgcc caagtccgtc
    12301 accggccgga tgtacgcggg cggcggtccg gccgacctgg tcgccgcgct gctcgccgtc
    12361 cgggacggcg tggtcccggc gaccgcgcac accacgtcgg tgcccgccgg ctacggcatc
    12421 gacctcgtcc tcggggaacc ccgcgccctg cccgtacggg ccgcgctggt gctcgcccgc
    12481 ggacgctggg gcttcaactc ggcggtcgtc gtgaccggtc cgacgcactg acgccccccc
    12541 ttcgacccca tcaattcctg gcaggagacc acgtcatggc acacatccag atcgacgacc
    12601 tgcggcgcat cctcgtcgcc tgcgccggcg aggacgacgg catcgacctg agcggcgaca
    12661 tcctcgacac ctccttcggt gacctggggt acgactcgct cgccctgatg gagaccgccg
    12721 cccggatcga acgggactac ggggtcgccc tcgcggacga cgtgatcgcc gacgcgagga
    12781 cgccgcgcga cctgctcgac ctggtcaacc gggccgtccc ggcggacgcc cggtgacggc
    12841 cggaccccgc ccgctgcacg ccgagcacac ccgggtggtg cacgcgccgc ccggtccgct
    12901 gtacgacctg gtggcggacg tgacgctgtg gccggccgtc ttcggcccca ccgtgcacgc
    12961 ccgccggctg gaaggcggcc cggacagcga gcggatccgg ctctgggcga cggtgaacgg
    13021 ccgggtgagc gactgggtgt cgcgccgcac cctcgatccg ggccggttca cggtcggctt
    13081 cgagcaggag gtcagcagtg cgccggtcgc ctcgatgggc ggcgagtggc tcttccgtga
    13141 gctgggcggc ggccggaccg aggtcgtcct gcggcaccac ttcacggtcg tcgacgacga
    13201 cccggccgcc gtgtcctggg tgcaggaggc gctggaccgc aacagcgcgg cggaactcgg
    13261 cgcgctggcc cgggtcgtgg agaccgggca cccgccgcgg gagatcgtgt tctcgttcac
    13321 cgacaccctc gcgctgaccg gcccggcgga gtcggcctac gagttcgtcg cccgggccga
    13381 cctgtggccg gagcggcttc cgcacgtggc cggggtgacc ctcaccgaga ccgcgcccgg
    13441 ggtgcaggac ctgcggatgg agacggcgac ggcggacggc tcgacccaca ccacccattc
    13501 ggtacgggtg tgccggcggc cggagtggat cgcgtacaag cagctccgta ccccggagct
    13561 gctgctcggg cacagcgggc tgtggacgtt cggcgaggga ccggacggac cgttcgccac
    13621 cgcgagccac acggtggccc tgaacccgga ggcggtgtcc cgggtgctgg gggcggaccg
    13681 cacgaccgcg gacgcccgac ggcacgtgcg ggaactgctc ggccgcaaca gccgcaccac
    13741 gctggcgcac gcggccggac aggaggcacc ggcccggtag ccgacgggcg gctgacggct
    13801 gacggctgac ggctgacgaa cgagaacgcg aacgcgaacg cgaacggcga ggcacgtaca
    13861 ggggaggccc ggcggtgaac caccgccggg gcctcgccgt tcaggccgtt cgccccttca
    13921 gcctctccgc ccgttcagcc gtccgtgatc cgggtcctgg cgagcagggc gggtccgtcg
    13981 gggcggccgg tgacgacgcc gttcatgccc ttcgacggct gctcccagcg gtagccccag
    14041 acgg
//
