NITE - Chemical Management Field

Latest GHS Classification Results by the Japanese Government (edited by NITE)

GENERAL INFORMATION

Item	Information
CAS RN	13987-01-4
Chemical Name	Propylene trimer
Substance ID	m-nite-13987-01-4_v1
Download of Excel format	Excel file

REFERENCE INFORMATION

Item	Information
Guidance used for the classification (External link)	To Guidance List
UN GHS document (External link)	To UN GHS document
FAQ（GHS classification results by the Japanese Government）	To FAQ
List of Information Sources (Excel file)	List of Information Sources
List of Definitions/Abbreviations	Definitions/Abbreviations
Sample Label by MHLW (External link)	MHLW Website (in Japanese Only)
Sample SDS by MHLW (External link)	MHLW Website (in Japanese Only)
OECD/eChemPortal (External link)	To OECD/eChemPortal (External link)

PHYSICAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
1	Explosives	Not classified (Not applicable)	- -	-	-	There are no chemical groups associated with explosive properties present in the molecules.	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
2	Flammable gases	Not classified (Not applicable)	- -	-	-	Liquid (GHS definition)	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
3	Aerosols	Not classified (Not applicable)	- -	-	-	Not aerosol products	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
4	Oxidizing gases	Not classified (Not applicable)	- -	-	-	Liquid (GHS definition)	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
5	Gases under pressure	Not classified (Not applicable)	- -	-	-	Liquid (GHS definition)	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
6	Flammable liquids	Category 2	Danger	H225	P303+P361+P353 P370+P378 P403+P235 P210 P233 P240 P241 P242 P243 P280 P501	Classified into Category 2 since flash point 24 degC (open-cup) is <23 degC (closed-cup) and initial boiling point 133 - 142 degC is >35 degC (NFPA (13th, 2006)), further the substance is classified into Class 3, PG II, III in UNRTDG (UN2057). However, classified into Category 3 from PG III in UNRTDG (UN2057), therefore, tests should be conducted by products to establish the classification.	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
7	Flammable solids	Not classified (Not applicable)	- -	-	-	Liquid (GHS definition)	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
8	Self-reactive substances and mixtures	Type G	- -	-	-	Classified into Type G since the substance does not fall into upper Division 4.1 (Self-reactive substances and mixtures) from which it is classified into Class 3 in UNRTDG (UN2057) though there are chemical groups (unsaturated bond) present in the molecule associated with self-reactive properties.	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
9	Pyrophoric liquids	Not classified	- -	-	-	Classified into Not classified since auto-ignition point is 260 degC (Hommel (1996)) exceeding 70 degC.	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
10	Pyrophoric solids	Not classified (Not applicable)	- -	-	-	Liquid (GHS definition)	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
11	Self-heating substances and mixtures	Classification not possible	- -	-	-	Test methods applicable to liquid substances are not available.	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
12	Substances and mixtures which, in contact with water, emit flammable gases	Not classified (Not applicable)	- -	-	-	The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
13	Oxidizing liquids	Not classified (Not applicable)	- -	-	-	Containing no oxygen, fluorine or chlorine in the molecule	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
14	Oxidizing solids	Not classified (Not applicable)	- -	-	-	Liquid (GHS definition)	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
15	Organic peroxides	Not classified (Not applicable)	- -	-	-	Organic compounds containing no bivalent -O-O- structure	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
16	Corrosive to metals	Classification not possible	- -	-	-	No data available.	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
17	Desensitized explosives	-	- -	-	-	-	-	-

HEALTH HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
1	Acute toxicity (Oral)	Classification not possible	- -	-	-	No data available. The LD50 values of the analogs for rats are as follows; CAS No. 68526-55-6 (Alkenes, C8-10, C9-rich): >2332 mg/kg (SIDS (2004)), CAS No. 97593-01-6 (Alkenes, C8-10, C9-rich): >2350 mg/kg (IUCLID (2000)), and CAS No. 27215-95-8 (Nonene): 2100 mg/kg (IUCLID (2000)). All analogs correspond to "Not classified" in JIS Classification (correspond to Category 5 in GHS classification).	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
1	Acute toxicity (Dermal)	Classification not possible	- -	-	-	No data available. The LD50 values of the analogs for rabbits are as follows; CAS No. 68526-55-6 (Alkenes, C8-10, C9-rich): > 2332 mg/kg (SIDS (2004)), CAS No. 97593-01-6 (Alkenes, C8-10, C9-rich): >2350 mg/kg (IUCLID (2000)), and CAS No. 27215-95-8 (Nonene): 5000 mg/kg (IUCLID (2000)). All analogs correspond to "Not classified" in JIS Classification (correspond to Category 5 in GHS classification).	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
1	Acute toxicity (Inhalation: Gases)	Not classified (Not applicable)	- -	-	-	Liquid (GHS definition)	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
1	Acute toxicity (Inhalation: Vapours)	Classification not possible	- -	-	-	No data available. LC50 values of the analogs for rats are as follows; CAS No. 68526-55-6 (Alkenes, C8-10, C9-rich): >13.6 mg/L (vapour) (4-hour equivalence) (SIDS (2004)) and CAS No. 97593-01-6 (Alkenes, C8-10, C9-rich): 22.7 mg/L (IUCLID (2000)). The analogs correspond to Category 4 or "Not classified".	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
1	Acute toxicity (Inhalation: Dusts and mists)	Classification not possible	- -	-	-	No data available.	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
2	Skin corrosion/irritation	Classification not possible	- -	-	-	No data available. As relevant information, there are reports that in a rabbit 24-hour exposure occlusive dressing irritation test, the analogs, CAS No. 68526-55-6 (Alkenes, C8-10, C9-rich) and CAS No. 97593-01-6 (Alkenes, C8-10, C9-rich) induced slight erythema along with desquamation (SIDS (2004), IUCLID (2000)). These analogs correspond to "Not classified" in JIS Classification (correspond to Category 3 in GHS classification).	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
3	Serious eye damage/eye irritation	Classification not possible	- -	-	-	No data available. As relevant information, there are reports that in a rabbit eye irritation test (Draize method), the analog, CAS No. 68526-55-6 (Alkenes, C8-10, C9-rich) induced "mild conjunctival irritation cleared by 24-hour" (SIDS (2004)) and another analog, CAS No. 97593-01-6 (Alkenes, C8-10, C9-rich) was estimated to be "slightly irritating " (IUCLID (2000)). These analogs correspond to "Not classified".	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
4	Respiratory sensitization	Classification not possible	- -	-	-	No data available.	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
4	Skin sensitization	Classification not possible	- -	-	-	No data available. For the analogs, CAS No. 68526-55-6 (Alkenes, C8-10, C9-rich) and CAS No. 97593-01-6 (Alkenes, C8-10, C9-rich), negative results in a guinea pig skin sensitization test (Maximization test, OECD TG406) were reported (IUCLID (2000)).	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
5	Germ cell mutagenicity	Classification not possible	- -	-	-	No data available. As relevant information, the analogs, CAS No. 68526-55-6 (Alkenes, C8-10, C9-rich) and CAS No. 97593-01-6 (Alkenes, C8-10, C9-rich) correspond to "Not classified" based on negative results in mouse bone marrow micronucleus tests (in vivo somatic cell mutagenicity tests, GLP) (SIDS (2004), IUCLID (2000)). In addition, the results of bacteria reverse mutation tests (in vitro mutagenicity tests, GLP) of these analogs were also negative (SIDS (2004), IUCLID (2000)).	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
6	Carcinogenicity	Classification not possible	- -	-	-	No data available.	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
7	Reproductive toxicity	Classification not possible	- -	-	-	No data available.	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
8	Specific target organ toxicity - Single exposure	Classification not possible	- -	-	-	No data available. As relevant information, for the analogs, CAS No. 68526-55-6 (Alkenes, C8-10, C9-rich), nasal discharge and congested adrenal glands were observed at higher dose levels (73.5 mg/kg and higher) in a rat oral test (SIDS (2004)); atonia was observed at a dose level of 73.8 mg/kg in a rabbit dermal test (SIDS (2004)); and in a inhalation test with mice, rats and guinea pigs, at a dose level of 11.1 mg/L, mice exhibited labored breathing patterns, rats exhibited limb ataxia and general lethargic behavior and guinea pigs showed slight tremors (SIDS (2004)). Since the respiratory system, central nervous system and adrenal gland are regarded as target organs, the substance was classified into Category 1 (nasal cavity, adrenal gland) and Category 2 (respiratory system, central nervous system).	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
9	Specific target organ toxicity - Repeated exposure	Classification not possible	- -	-	-	No data available.	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
10	Aspiration hazard	Classification not possible	- -	-	-	No data available. As relevant information, for the analog, nonene, there are reports of "an aspiration hazard when ingested" and "irritating to skin, eye, nose and throat, and anesthetic in high concentration" (PATTY (5th, 2001)). In addition, C6-C18 alkenes were assessed for aspiration hazard in an animal test using rats. All animals exposed to C8 to C14 died within 24-hour and the affected animals showed chemical pneumonitis. The report concluded that there is a significant aspiration hazard with C6 to C14 alkenes (SIDS (2004)).	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
11	Hazardous to the aquatic environment Short term (Acute)	Classification not possible	- -	-	-	Classification not possible due to lack of data.	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
11	Hazardous to the aquatic environment Long term (Chronic)	Classification not possible	- -	-	-	Classification not possible due to lack of data.	FY2009	GHS Classification Guidance by the Japanese Government （March, 2009）
12	Hazardous to the ozone layer	-	- -	-	-	-	-	-

NOTE:

GHS Classification Result by the Japanese Government is intended to provide a reference for preparing a GHS label or SDS for users. To include the same classification result in a label or SDS for Japan is NOT mandatory.
Users can cite or copy this classification result when preparing a GHS label or SDS. Please be aware, however, that the responsibility for a label or SDS prepared by citing or copying this classification result lies with users.
This GHS classification was conducted based on the information sources and the guidance for classification and judgement which are described in the GHS Classification Guidance for the Japanese Government etc. Using other literature, test results etc. as evidence and including different content from this classification result in a label or SDS are allowed.
Hazard statement and precautionary statement will show by hovering the mouse cursor over a code in the column of "Hazard statement" and "Precautionary statement," respectively. In the excel file, both the codes and statements are provided.
A blank or "-" in the column of "Classification" denotes that a classification for the hazard class was not conducted in the year.
An asterisk “*” in the column of “Classification” denotes that “Not classified (or No applicable)” and/or “Classification not possible” is applicable. Details are described in the column of “Rationale for the classification”. If no English translation is available for “Rationale for the classification,” please refer to the Japanese version of the results.

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