NITE - Chemical Management Field

Latest GHS Classification Results by the Japanese Government (edited by NITE)

GENERAL INFORMATION

Item	Information
CAS RN	8009-03-8
Chemical Name	Petrolatum; Petrolatum
Substance ID	m-nite-8009-03-8_v1
Download of Excel format	Excel file

REFERENCE INFORMATION

Item	Information
Guidance used for the classification (External link)	To Guidance List
UN GHS document (External link)	To UN GHS document
FAQ（GHS classification results by the Japanese Government）	To FAQ
List of Information Sources (Excel file)	List of Information Sources
List of Definitions/Abbreviations	Definitions/Abbreviations
Sample Label by MHLW (External link)	MHLW Website (in Japanese Only)
Sample SDS by MHLW (External link)	MHLW Website (in Japanese Only)
OECD/eChemPortal (External link)	To OECD/eChemPortal (External link)

PHYSICAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
1	Explosives	Classification not possible	- -	-	-	Due to dissociation of nitrogen and oxygen from hydrocarbon through the formation of ammonia and water, the saturation of unsaturated bonds and the deposition and separation of its metal components by the catalysts during the hydrorefining process, the substance does not contain chemical groups associated with explosive properties.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
2	Flammable gases	Not classified (Not applicable)	- -	-	-	The substance is a semi solid (Merck (14th, 2006)) and it is assumed to be a liquid at ordinary temperature.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
3	Aerosols	Not classified (Not applicable)	- -	-	-	Not aerosol products.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
4	Oxidizing gases	Not classified (Not applicable)	- -	-	-	The substance is a semi solid (Merck (14th, 2006)) and it is assumed to be a liquid at ordinary temperature.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
5	Gases under pressure	Not classified (Not applicable)	- -	-	-	The substance is a semi solid (Merck (14th, 2006)) and it is assumed to be a liquid at ordinary temperature.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
6	Flammable liquids	Not classified	- -	-	-	Since it is a semi solid (Merck (14th, 2006)) and its flash point is 182-221degC (ICSC (2002)), the substance was classified into "Not classified".	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
7	Flammable solids	Not classified (Not applicable)	- -	-	-	The substance is a semi solid (Merck (14th, 2006)) and it is assumed to be a liquid at ordinary temperature.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
8	Self-reactive substances and mixtures	Not classified (Not applicable)	- -	-	-	Due to dissociation of nitrogen and oxygen from hydrocarbon through the formation of ammonia and water, the saturation of unsaturated bonds and the deposition and separation of its metal components by the catalysts during the hydrorefining process, the substance does not contain chemical groups associated with explosive or self-reactive properties.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
9	Pyrophoric liquids	Not classified	- -	-	-	Its autoignition point is > 290degC (ICSC (2002), ICSC (J) (2002)).	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
10	Pyrophoric solids	Not classified (Not applicable)	- -	-	-	The substance is a semi solid (Merck (14th, 2006)) and it is assumed to be a liquid at ordinary temperature.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
11	Self-heating substances and mixtures	Classification not possible	- -	-	-	No data available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
12	Substances and mixtures which, in contact with water, emit flammable gases	Not classified (Not applicable)	- -	-	-	Due to deposition and separation of its metal components by the catalysts during the hydrorefining process, the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, and At).	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
13	Oxidizing liquids	Not classified (Not applicable)	- -	-	-	The substance is a semi solid (Merck (14th, 2006)) and it is assumed to be a liquid at ordinary temperature.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
14	Oxidizing solids	Not classified (Not applicable)	- -	-	-	The substance does not contain oxygen, fluorine or chlorine.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
15	Organic peroxides	Not classified (Not applicable)	- -	-	-	Organic compounds containing no bivalent -O-O- structure in the molecule	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
16	Corrosive to metals	Classification not possible	- -	-	-	Its melting point is around 55degC; classification is not possible due to lack of data.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
17	Desensitized explosives	-	- -	-	-	-	-	-

HEALTH HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
1	Acute toxicity (Oral)	Classification not possible	- -	-	-	No data available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
1	Acute toxicity (Dermal)	Classification not possible	- -	-	-	No data available. As relevant notes, its mixture with paraffin wax (CAS No. 8002-74-2) (1-to-1 ratio) has a rabbit LD50 value of 3600 mg/kg bw (IUCLID (2000)).	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
1	Acute toxicity (Inhalation: Gases)	Not classified (Not applicable)	- -	-	-	The substance is a semi solid (Merck (14th, 2006)) and it is assumed to be a liquid at ordinary temperature.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
1	Acute toxicity (Inhalation: Vapours)	Classification not possible	- -	-	-	No data available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
1	Acute toxicity (Inhalation: Dusts and mists)	Classification not possible	- -	-	-	No data available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
2	Skin corrosion/irritation	Not classified	- -	-	-	According to Patty (5th, 2001), the substance is non-irritating, and it is documented to be used as a dermal test vehicle. Based on these reports, the substance was classified into "Not classified".	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
3	Serious eye damage/eye irritation	Category 2B	- Warning	H320	P305+P351+P338 P337+P313 P264	Since the substance was evaluated to be slightly irritating in rabbits (IUCLID, (2000)), it was classified into Category 2B.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
4	Respiratory sensitization	Classification not possible	- -	-	-	No data available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
4	Skin sensitization	Not classified	- -	-	-	Based on the following documents, the substance was classified into "Not classified": the substance was evaluated to be not sensitizing in humans (IUCLID (2000)); although dermatitis developed by repeated exposure, the substance was not sensitizing (IUCLID (2000)); and the substance is nonallergenic and is used as a dermal test vehicle (Patty (5th, 2001)).	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
5	Germ cell mutagenicity	Classification not possible	- -	-	-	No data available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
6	Carcinogenicity	Classification not possible	- -	-	-	In mixed diet tests using rats (FDRL, about 3000 mg/kg/day), no signs of carcinogenicity were detected in the application of either two kinds of white substances or one yellow substance (color differences were due to the degree of refinement) (EHC 20 (1982)). Similarly, the 80-week dermal administration tests using mice that were treated with 25 or 50 mg did not find signs of carcinogenicity (IUCLID (2000)). In addition, according to Patty, the highly refined substance showed little or no signs of carcinogenicity (Patty (5th, 2001)). Referring to the EU classification, the substance of low refinement (yellow, amber, and brown vaseline) is for industrial use, and it sometimes contains polycyclic aromatics that are carcinogenic, and therefore, it is rated as Category 2 (equivalent to Category 1B based on the JIS classification criteria) (EU-Annex 1 (accessed in September 2008)). Overall, since information on low-refined, yellow substance is not available, the substance was classified into "Classification not possible".	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
7	Reproductive toxicity	Classification not possible	- -	-	-	No data available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
8	Specific target organ toxicity - Single exposure	Classification not possible	- -	-	-	In a skin test using rabbits that were exposed to 4 ml/kg for 24 hours, toxic symptoms (abnormalities found in autopsy or systemic effects) were not recognized. However, test substance was a mixture with paraffin (CAS No. 8002-74-2) (1-to-1 ratio) (IUCLID (2000)). Since the information gathered was of this test and a hypodermic administration test only (IUCLID (2000)), the substance was classified into "Classification not possible" due to lack of data.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
9	Specific target organ toxicity - Repeated exposure	Classification not possible	- -	-	-	In 2-year mixed diet tests using rats (FDRL, about 3000 mg/kg/day, (90-day correction: 24000 mg/kg/day)), no toxic symptoms (abnormalities in behavior, mortality rate, blood items, urine, organs, and tissues) were detected in the application of either two kinds of white substances or one yellow substance (color differences were due to the degree of refinement) (IUCLID (2000)). This document indicates that the substance is to be rated as "Not classified" for oral administration; however, since no information on other routes is available, the substance was classified into "Classification not possible".	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
10	Aspiration hazard	Classification not possible	- -	-	-	No data available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
11	Hazardous to the aquatic environment Short term (Acute)	Classification not possible	- -	-	-	No data available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
11	Hazardous to the aquatic environment Long term (Chronic)	Classification not possible	- -	-	-	No data available.	FY2008	GHS Classification Guidance by the Japanese Government （Sep, 2008）
12	Hazardous to the ozone layer	-	- -	-	-	-	-	-

NOTE:

GHS Classification Result by the Japanese Government is intended to provide a reference for preparing a GHS label or SDS for users. To include the same classification result in a label or SDS for Japan is NOT mandatory.
Users can cite or copy this classification result when preparing a GHS label or SDS. Please be aware, however, that the responsibility for a label or SDS prepared by citing or copying this classification result lies with users.
This GHS classification was conducted based on the information sources and the guidance for classification and judgement which are described in the GHS Classification Guidance for the Japanese Government etc. Using other literature, test results etc. as evidence and including different content from this classification result in a label or SDS are allowed.
Hazard statement and precautionary statement will show by hovering the mouse cursor over a code in the column of "Hazard statement" and "Precautionary statement," respectively. In the excel file, both the codes and statements are provided.
A blank or "-" in the column of "Classification" denotes that a classification for the hazard class was not conducted in the year.
An asterisk “*” in the column of “Classification” denotes that “Not classified (or No applicable)” and/or “Classification not possible” is applicable. Details are described in the column of “Rationale for the classification”. If no English translation is available for “Rationale for the classification,” please refer to the Japanese version of the results.

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