NITE - Chemical Management Field

Latest GHS Classification Results by the Japanese Government (edited by NITE)

GENERAL INFORMATION

Item	Information
CAS RN
Chemical Name	Coal tar naphtha
Substance ID	m-nite-nocas-0008_v1
Download of Excel format	Excel file

REFERENCE INFORMATION

Item	Information
Guidance used for the classification (External link)	To Guidance List
UN GHS document (External link)	To UN GHS document
FAQ（GHS classification results by the Japanese Government）	To FAQ
List of Information Sources (Excel file)	List of Information Sources
List of Definitions/Abbreviations	Definitions/Abbreviations
Sample Label by MHLW (External link)	MHLW Website (in Japanese Only)
Sample SDS by MHLW (External link)	MHLW Website (in Japanese Only)
OECD/eChemPortal (External link)	To OECD/eChemPortal (External link)

PHYSICAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
1	Explosives	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
2	Flammable gases	Not classified (Not applicable)	- -	-	-	Liquid (room temperature)	FY2006	GHS Classification Manual （10 Feb, 2006）
3	Aerosols	Not classified (Not applicable)	- -	-	-	Not aerosol products	FY2006	GHS Classification Manual （10 Feb, 2006）
4	Oxidizing gases	Not classified (Not applicable)	- -	-	-	Liquid (room temperature)	FY2006	GHS Classification Manual （10 Feb, 2006）
5	Gases under pressure	Not classified (Not applicable)	- -	-	-	Liquid (room temperature)	FY2006	GHS Classification Manual （10 Feb, 2006）
6	Flammable liquids	Category 2	Danger	H225	P303+P361+P353 P370+P378 P403+P235 P210 P233 P240 P241 P242 P243 P280 P501	Since flash point was 21 degC (<23 degC), and initial boiling point was 160 - 300 degC (> 35 degC), it was classified as Category 2.	FY2006	GHS Classification Manual （10 Feb, 2006）
7	Flammable solids	Not classified (Not applicable)	- -	-	-	Liquid (room temperature)	FY2006	GHS Classification Manual （10 Feb, 2006）
8	Self-reactive substances and mixtures	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
9	Pyrophoric liquids	Not classified	- -	-	-	Flash point: 270degC (> 70degC)(NFPA , 1997)	FY2006	GHS Classification Manual （10 Feb, 2006）
10	Pyrophoric solids	Not classified (Not applicable)	- -	-	-	Liquid (room temperature)	FY2006	GHS Classification Manual （10 Feb, 2006）
11	Self-heating substances and mixtures	Classification not possible	- -	-	-	Test methods applicable to liquid substances are not available	FY2006	GHS Classification Manual （10 Feb, 2006）
12	Substances and mixtures which, in contact with water, emit flammable gases	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
13	Oxidizing liquids	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
14	Oxidizing solids	Not classified (Not applicable)	- -	-	-	Liquid (room temperature)	FY2006	GHS Classification Manual （10 Feb, 2006）
15	Organic peroxides	Classification not possible	- -	-	-	UNRTDG No. 3105 Class: 5.2	FY2006	GHS Classification Manual （10 Feb, 2006）
16	Corrosive to metals	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
17	Desensitized explosives	-	- -	-	-	-	-	-

HEALTH HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
1	Acute toxicity (Oral)	Not classified	- -	-	-	Based on the 5980mg/kg which is statistically calculated values of rat LD50 value using 4 data (IARC47 (1989), EHC20 (1982)), it considered as the outside of Category.	FY2006	GHS Classification Manual （10 Feb, 2006）
1	Acute toxicity (Dermal)	-	- Warning	-	-	Based on rat LD50= 5ml/kg (reduced value of 4.40g/kg) (IARC47 (1989), EHC20 (1982)), it was set as Category 5.	FY2006	GHS Classification Manual （10 Feb, 2006）
1	Acute toxicity (Inhalation: Gases)	Not classified (Not applicable)	- -	-	-	Liquid (room temperature)	FY2006	GHS Classification Manual （10 Feb, 2006）
1	Acute toxicity (Inhalation: Vapours)	Classification not possible	- -	-	-	Insufficient data available	FY2006	GHS Classification Manual （10 Feb, 2006）
1	Acute toxicity (Inhalation: Dusts and mists)	-	- Warning	-	-	Category 5 because of SPECIES: Rat; ENDPOINT: LC50 (4-8h) VALUE: 5.3mg/L (EHC20, 1982)	FY2006	GHS Classification Manual （10 Feb, 2006）
2	Skin corrosion/irritation	Category 2	Warning	H315	P302+P352 P332+P313 P362+P364 P264 P280 P321	Based on the statement of moderate irritation to Aromatic solvents which has a 138 - 264degC boiling range (EHC20 (1982)), it was classified as Category 2.	FY2006	GHS Classification Manual （10 Feb, 2006）
3	Serious eye damage/eye irritation	Category 2A	Warning	H319	P305+P351+P338 P337+P313 P264 P280	Based on the statement of moderately irritation to Aromatic solvents which has a 138 - 264degC boiling range (EHC20 (1982)), it was set as Category 2A.	FY2006	GHS Classification Manual （10 Feb, 2006）
4	Respiratory sensitization	Classification not possible	- -	-	-	Based on a ststement that in the maximization test (including GLP test ) using a guinea pigs, high-boiling aromatic solvent, coal tar naphtha did not cause the sensitization, it was put outside of the Category. In addition, this result is supported by the statement that sensitization is not indicated in the examination by humans using multiple solvent naphtha with different boiling points(IUCLID (2000)).	FY2006	GHS Classification Manual （10 Feb, 2006）
4	Skin sensitization	Not classified	- -	-	-	Based on a ststement that in the maximization test (including GLP test ) using a guinea pigs, high-boiling aromatic solvent, coal tar naphtha did not cause the sensitization, it was put outside of the Category. In addition, this result is supported by the statement that sensitization is not indicated in the examination by humans using multiple solvent naphtha with different boiling points(IUCLID (2000)).	FY2006	GHS Classification Manual （10 Feb, 2006）
5	Germ cell mutagenicity	Not classified	- -	-	-	Based on the description (IUCLID (2000)) that High Flash Aromatic Naphtha or Solvent naphtha gave negative for the in vivo somatic mutagenicity examination (the chromosomal aberration test (GLP), the micronucleus test (GLP)) using rats or mice, we classified it as Out Of Category. In addition, each in vitro mutagenicity test using three kinds of Solvent naphtha among which boiling points differ was negative. (IUCLID(2000))	FY2006	GHS Classification Manual （10 Feb, 2006）
6	Carcinogenicity	Classification not possible	- -	-	-	It was presupposed that it cannot be categoried by technological direction. Since there is only the European Union classification. [Notes] Solvent naphtha (coal), Solvent naphtha (petroleum), and light arom. are classified into the category 2 (May cause cancer) according to the European Union classification (ESIS (2006)).	FY2006	GHS Classification Manual （10 Feb, 2006）
7	Reproductive toxicity	Not classified	- -	-	-	Influences on the litter's count and fetal survivial and increased cleft palates were observed as a result of the two-generation reproductive toxicity test and developmental toxicity test of High-Flash Aromatic Naphtha (Cas64742-95-6) using rats and mice. However, this effect was observed only in the group of high-dose causing high motality to maternal animals(motality rate of mother rats and mice is 88% and 44% respectively), and reproductive toxicity or developmental toxicity was not observed at any lower dose rates (IUCLID (2000), Toxicol.Ind.Health, vol.6,441-460, 1990). Therefore, it was placed out of classification.	FY2006	GHS Classification Manual （10 Feb, 2006）
8	Specific target organ toxicity - Single exposure	Classification not possible	- -	-	-	No data available.	FY2006	GHS Classification Manual （10 Feb, 2006）
9	Specific target organ toxicity - Repeated exposure	Classification not possible	- -	-	-	Insufficient data available	FY2006	GHS Classification Manual （10 Feb, 2006）
10	Aspiration hazard	Category 1	Danger	H304	P301+P310 P331 P405 P501	We classified it as Category 1 based on that solvent naphtha has dynamic viscosity of 0.949mm 2/s (30 degrees C) (The Solvent Pocket Book (2001)), and that Aromatic solvent A4 (boiling points 196 to 264 degrees C) showed the fatality rates of 5/10 (EHC20 (1982)). In addition, Solvent naphtha (petroleum), light arom. (Cas 64742-95-6), Solvent naphtha (petroleum) and heavy arom. (Cas 64742-94-5) are classified as R65 (may cause lung damage if swallowed.) (ESIS (2006)).	FY2006	GHS Classification Manual （10 Feb, 2006）

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Pictogram Signal word	Hazard statement (code)	Precautionary statement (code)	Rationale for the classification	Classification year (FY)	GHS Classification Guidance for the Japanese Government
11	Hazardous to the aquatic environment Short term (Acute)	Classification not possible	- -	-	-	No data available	FY2006	GHS Classification Manual （10 Feb, 2006）
11	Hazardous to the aquatic environment Long term (Chronic)	Classification not possible	- -	-	-	No data available.	FY2006	GHS Classification Manual （10 Feb, 2006）
12	Hazardous to the ozone layer	-	- -	-	-	-	-	-

NOTE:

GHS Classification Result by the Japanese Government is intended to provide a reference for preparing a GHS label or SDS for users. To include the same classification result in a label or SDS for Japan is NOT mandatory.
Users can cite or copy this classification result when preparing a GHS label or SDS. Please be aware, however, that the responsibility for a label or SDS prepared by citing or copying this classification result lies with users.
This GHS classification was conducted based on the information sources and the guidance for classification and judgement which are described in the GHS Classification Guidance for the Japanese Government etc. Using other literature, test results etc. as evidence and including different content from this classification result in a label or SDS are allowed.
Hazard statement and precautionary statement will show by hovering the mouse cursor over a code in the column of "Hazard statement" and "Precautionary statement," respectively. In the excel file, both the codes and statements are provided.
A blank or "-" in the column of "Classification" denotes that a classification for the hazard class was not conducted in the year.
An asterisk “*” in the column of “Classification” denotes that “Not classified (or No applicable)” and/or “Classification not possible” is applicable. Details are described in the column of “Rationale for the classification”. If no English translation is available for “Rationale for the classification,” please refer to the Japanese version of the results.

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