BLAST table : Mith_00010

DB	UniProtKB

	accession	Evalue	Score	Ident.	link	product	gene	organism
1	Q194R9_STRAA (Q194R9)	0.0	820	100%	UniProt GenBank	Membrane protein		Streptomyces argillaceus
2	D9XAJ8_STRVR (D9XAJ8)	1e-166	588	84%	UniProt GenBank	Integral membrane transporter	SSQG_00653	Streptomyces viridochromogenes DSM 40736
3	A3KJW5_STRAM (A3KJW5)	1e-163	578	83%	UniProt GenBank	Putative integral membrane transport protein	SAML1014	Streptomyces ambofaciens ATCC 23877
4	B5I3U1_9ACTO (B5I3U1)	1e-161	573	85%	UniProt GenBank	Integral membrane transporter	SSEG_06044	Streptomyces sviceus ATCC 29083
5	Q9EX30_STRCO (Q9EX30)	1e-161	572	82%	UniProt GenBank	Putative integral membrane transport protein	SCO1010	Streptomyces coelicolor
6	D6EV88_STRLI (D6EV88)	1e-160	570	81%	UniProt GenBank	Integral membrane transporter	SSPG_06553	Streptomyces lividans TK24
7	E8WFJ2_STRFA (E8WFJ2)	1e-160	568	81%	UniProt GenBank	Integral membrane transport protein	Sfla_5797	Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD)
8	Q82N85_STRAW (Q82N85)	1e-159	567	83%	UniProt GenBank	Putative transporter	SAV1418 SAV_1418	Streptomyces avermitilis
9	B5H799_STRPR (B5H799)	1e-159	567	81%	UniProt GenBank	Integral membrane transporter	SSDG_01045	Streptomyces pristinaespiralis ATCC 25486
10	F2R8P2_STRVP (F2R8P2)	1e-153	546	81%	UniProt GenBank	Putative transporter	SVEN_0673	Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
11	D7C879_STRBB (D7C879)	1e-150	535	79%	UniProt GenBank	Transporter	SBI_01119	Streptomyces bingchenggensis (strain BCW-1)
12	D9WJQ3_9ACTO (D9WJQ3)	1e-149	534	78%	UniProt GenBank	Putative major facilitator superfamily (MFS) transporter	SSOG_01193	Streptomyces himastatinicus ATCC 53653
13	D6B265_9ACTO (D6B265)	1e-147	525	79%	UniProt GenBank	Putative uncharacterized protein	SSHG_05863	Streptomyces albus J1074
14	E0KJI5_STRVO (E0KJI5)	1e-140	502	75%	UniProt GenBank	General substrate transporter	StrviDRAFT_2838	Streptomyces violaceusniger Tu 4113
15	D6KE26_9ACTO (D6KE26)	1e-133	479	69%	UniProt GenBank	Major facilitator superfamily transporter	SSTG_05201	Streptomyces sp. e14
16	F8JUX4_STRCT (F8JUX4)	1e-131	471	68%	UniProt GenBank	Integral membrane transport protein	SCAT_5762	Streptomyces cattleya
17	D6AD17_STRFL (D6AD17)	1e-127	458	61%	UniProt GenBank	Putative uncharacterized protein	SSGG_06075	Streptomyces roseosporus NRRL 15998
18	B1VV41_STRGG (B1VV41)	1e-126	456	66%	UniProt GenBank	Putative permease of the major facilitator superfamily	SGR_1196	Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
19	D3PUT9_STANL (D3PUT9)	1e-125	452	68%	UniProt GenBank	Major facilitator superfamily MFS_1	Snas_5329	Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
20	D7AZT9_NOCDD (D7AZT9)	1e-123	447	65%	UniProt GenBank	Metabolite/H+ symporter, major facilitator superfamily (MFS)	Ndas_2798	Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488) Actinomadura dassonvillei
21	B4VET6_9ACTO (B4VET6)	1e-122	442	65%	UniProt GenBank	Integral membrane transport protein	SSAG_06317	Streptomyces sp. Mg1
22	D8HN12_AMYMU (D8HN12)	1e-119	433	65%	UniProt GenBank	Major facilitator transporter	AMED_5953	Amycolatopsis mediterranei (strain U-32)
23	D6A000_9ACTO (D6A000)	1e-119	432	64%	UniProt GenBank	Metabolite transporter	SSFG_00647	Streptomyces ghanaensis ATCC 14672
24	E4N5Y4_KITSK (E4N5Y4)	1e-119	431	62%	UniProt GenBank	Putative major facilitator superfamily transporter	KSE_07760	Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054) Streptomyces setae
25	D9VML2_9ACTO (D9VML2)	1e-116	424	66%	UniProt GenBank	Integral membrane transporter	SSNG_00620	Streptomyces sp. C
26	D2B2D2_STRRD (D2B2D2)	1e-115	419	68%	UniProt GenBank	Putative transport protein	Sros_8515	Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
27	D2PL79_KRIFD (D2PL79)	1e-113	414	60%	UniProt GenBank	Major facilitator superfamily MFS_1	Kfla_5321	Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399)
28	D9XMY2_9ACTO (D9XMY2)	1e-112	410	63%	UniProt GenBank	Major facilitator superfamily transporter (MFS) transporter	SSRG_06135	Streptomyces griseoflavus Tu4000
29	D9V6D9_9ACTO (D9V6D9)	1e-111	406	62%	UniProt GenBank	Integral membrane transporter	SSMG_07222	Streptomyces sp. AA4
30	E2Q1H3_STRCL (E2Q1H3)	1e-111	405	63%	UniProt GenBank	Major facilitator superfamily permease	SCLAV_5532	Streptomyces clavuligerus ATCC 27064
31	C7MYB3_SACVD (C7MYB3)	1e-110	404	62%	UniProt GenBank	Nitrate/nitrite transporter	Svir_10040	Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)
32	A4FP75_SACEN (A4FP75)	1e-107	394	63%	UniProt GenBank	Metabolite transporter, MFS superfamily	SACE_6684	Saccharopolyspora erythraea (strain NRRL 23338)
33	A4FG14_SACEN (A4FG14)	1e-101	373	62%	UniProt GenBank	Integral membrane transport protein	SACE_3717	Saccharopolyspora erythraea (strain NRRL 23338)
34	Q0RZN0_RHOSR (Q0RZN0)	1e-100	370	54%	UniProt GenBank	Probable metabolite transporter, MFS superfamily protein	RHA1_ro08211	Rhodococcus sp. (strain RHA1)
35	C8XCF3_NAKMY (C8XCF3)	2e-99	367	58%	UniProt GenBank	General substrate transporter	Namu_1111	Nakamurella multipartita (strain ATCC 700099 / DSM 44233 / JCM 9543 / Y-104) Microsphaera multipartita
36	C7Q3V0_CATAD (C7Q3V0)	3e-92	343	52%	UniProt GenBank	General substrate transporter	Caci_8895	Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
37	Q0S9X9_RHOSR (Q0S9X9)	3e-88	330	49%	UniProt GenBank	Metabolite transporter, MFS superfamily protein	RHA1_ro03857	Rhodococcus sp. (strain RHA1)
38	A3TNL2_9MICO (A3TNL2)	7e-88	329	54%	UniProt GenBank	Putative integral membrane transport protein	JNB_14188	Janibacter sp. HTCC2649
39	A4FGP1_SACEN (A4FGP1)	1e-86	325	51%	UniProt GenBank	Metabolite transporter, MFS superfamily	SACE_3945	Saccharopolyspora erythraea (strain NRRL 23338)
40	D9V0Y8_9ACTO (D9V0Y8)	1e-85	322	48%	UniProt GenBank	Metabolite transporter	SSMG_02418	Streptomyces sp. AA4
41	F5XPT5_9ACTO (F5XPT5)	2e-85	321	53%	UniProt GenBank	Major facilitator superfamily transporter	MLP_13790	Microlunatus phosphovorus NM-1
42	E3FP79_STIAD (E3FP79)	2e-85	320	55%	UniProt GenBank	Major facilitator superfamily transporter	STAUR_4105	Stigmatella aurantiaca (strain DW4/3-1)
43	A0R513_MYCS2 (A0R513)	4e-85	320	50%	UniProt GenBank	Major facilitator superfamily protein MFS_1	MSMEG_6027	Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
44	B1T2W6_9BURK (B1T2W6)	9e-85	318	49%	UniProt GenBank	Major facilitator superfamily MFS_1	BamMEX5DRAFT_2132	Burkholderia ambifaria MEX-5
45	B1YY14_BURA4 (B1YY14)	2e-84	317	49%	UniProt GenBank	Major facilitator superfamily MFS_1	BamMC406_4694	Burkholderia ambifaria (strain MC40-6)
46	F0GK95_9BURK (F0GK95)	4e-84	317	46%	UniProt GenBank	Major facilitator transporter	B1M_43395	Burkholderia sp. TJI49
47	Q0B7Z8_BURCM (Q0B7Z8)	4e-84	316	49%	UniProt GenBank	Major facilitator superfamily MFS_1	Bamb_4172	Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) Burkholderia cepacia (strain AMMD)
48	Q89W04_BRAJA (Q89W04)	5e-84	316	51%	UniProt GenBank	Bll0889 protein	bll0889	Bradyrhizobium japonicum
49	Q1B2S8_MYCSS (Q1B2S8)	1e-83	315	49%	UniProt GenBank	General substrate transporter	Mmcs_4702	Mycobacterium sp. (strain MCS)
50	A3Q6S4_MYCSJ (A3Q6S4)	1e-83	315	49%	UniProt GenBank	General substrate transporter	Mjls_5087	Mycobacterium sp. (strain JLS)
51	A1UMC0_MYCSK (A1UMC0)	1e-83	315	49%	UniProt GenBank	General substrate transporter	Mkms_4788	Mycobacterium sp. (strain KMS)
52	Q398S2_BURS3 (Q398S2)	1e-83	315	49%	UniProt GenBank	Major facilitator superfamily (MFS_1) transporter	Bcep18194_B0925	Burkholderia sp. (strain 383) Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194)
53	B1FPP5_9BURK (B1FPP5)	1e-83	315	49%	UniProt GenBank	Major facilitator superfamily MFS_1	BamIOP4010DRAFT_6006	Burkholderia ambifaria IOP40-10
54	Q1BPI2_BURCA (Q1BPI2)	2e-83	314	45%	UniProt GenBank	Major facilitator superfamily MFS_1	Bcen_3580	Burkholderia cenocepacia (strain AU 1054)
55	B1K966_BURCC (B1K966)	2e-83	314	45%	UniProt GenBank	Major facilitator superfamily MFS_1	Bcenmc03_5496	Burkholderia cenocepacia (strain MC0-3)
56	A0B1J5_BURCH (A0B1J5)	2e-83	314	45%	UniProt GenBank	Major facilitator superfamily MFS_1	Bcen2424_4787	Burkholderia cenocepacia (strain HI2424)
57	A2W448_9BURK (A2W448)	2e-83	314	45%	UniProt GenBank	General substrate transporter:Major facilitator superfamily	BCPG_05141	Burkholderia cenocepacia PC184
58	F2LLX1_BURGA (F2LLX1)	3e-83	313	46%	UniProt GenBank	Major facilitator transporter	bgla_2g13710	Burkholderia gladioli BSR3
59	B9C106_9BURK (B9C106)	3e-83	313	50%	UniProt GenBank	Shikimate transporter	BURMUCGD2M_4346	Burkholderia multivorans CGD2M
60	B9BH95_9BURK (B9BH95)	3e-83	313	50%	UniProt GenBank	Shikimate transporter	BURMUCGD2_4357	Burkholderia multivorans CGD2
61	C0ZWR5_RHOE4 (C0ZWR5)	8e-82	308	47%	UniProt GenBank	Putative MFS transporter	RER_20920	Rhodococcus erythropolis (strain PR4 / NBRC 100887)
62	C3JGD5_RHOER (C3JGD5)	9e-82	308	48%	UniProt GenBank	Shikimate transporter	RHOER0001_4272	Rhodococcus erythropolis SK121
63	Q0S7C2_RHOSR (Q0S7C2)	9e-82	308	48%	UniProt GenBank	Metabolite transporter, MFS superfamily protein	RHA1_ro04779	Rhodococcus sp. (strain RHA1)
64	C1BBR3_RHOOB (C1BBR3)	1e-81	308	48%	UniProt GenBank	Putative MFS transporter	ROP_48690	Rhodococcus opacus (strain B4)
65	B4EMW8_BURCJ (B4EMW8)	2e-81	307	48%	UniProt GenBank	Major Facilitator Superfamily protein	BceJ2315_54300 BCAM1986	Burkholderia cepacia (strain J2315 / LMG 16656) Burkholderia cenocepacia (strain J2315)
66	A9APG7_BURM1 (A9APG7)	2e-81	307	50%	UniProt GenBank	Major facilitator superfamily MFS_1 Permease of the major facilitator superfamily	BMULJ_04705 Bmul_3813	Burkholderia multivorans (strain ATCC 17616 / 249)
67	B9B5Z5_9BURK (B9B5Z5)	4e-81	306	48%	UniProt GenBank	Major facilitator superfamily MFS_1	BURMUCGD1_6254	Burkholderia multivorans CGD1
68	A9ASX3_BURM1 (A9ASX3)	5e-81	306	48%	UniProt GenBank	Major facilitator superfamily MFS_1 Permease of the major facilitator superfamily	BMULJ_05540 Bmul_5987	Burkholderia multivorans (strain ATCC 17616 / 249)
69	B9C9G1_9BURK (B9C9G1)	6e-81	306	48%	UniProt GenBank	Major facilitator superfamily MFS_1	BURMUCGD2M_6482	Burkholderia multivorans CGD2M
70	B9BP71_9BURK (B9BP71)	6e-81	306	48%	UniProt GenBank	Major facilitator superfamily MFS_1	BURMUCGD2_6492	Burkholderia multivorans CGD2
71	B9AZ87_9BURK (B9AZ87)	8e-81	305	49%	UniProt GenBank	Shikimate transporter	BURMUCGD1_4010	Burkholderia multivorans CGD1
72	D3HS89_LEGLN (D3HS89)	9e-81	305	47%	UniProt GenBank	Shikimate transporter	shiA LLO_1408	Legionella longbeachae serogroup 1 (strain NSW150)
73	D1REY3_LEGLO (D1REY3)	9e-81	305	47%	UniProt GenBank	Shikimate transporter	shiA LLB_0246	Legionella longbeachae D-4968
74	A0JUJ3_ARTS2 (A0JUJ3)	9e-81	305	47%	UniProt GenBank	General substrate transporter	Arth_1319	Arthrobacter sp. (strain FB24)
75	E6THH7_MYCSR (E6THH7)	1e-80	305	47%	UniProt GenBank	Sugar phosphate permease	Mspyr1_46960	Mycobacterium sp. (strain Spyr1)
76	F4CMT4_9PSEU (F4CMT4)	1e-80	305	44%	UniProt GenBank	General substrate transporter	Psed_2833	Pseudonocardia dioxanivorans CB1190
77	A1TFX1_MYCVP (A1TFX1)	1e-80	305	47%	UniProt GenBank	Major facilitator superfamily MFS_1	Mvan_5300	Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
78	Q6JHP9_9PSEU (Q6JHP9)	2e-80	304	46%	UniProt GenBank	Putative transporter		Saccharopolyspora spinosa
79	A4T5I4_MYCGI (A4T5I4)	2e-80	304	48%	UniProt GenBank	General substrate transporter	Mflv_1471	Mycobacterium gilvum (strain PYR-GCK) Mycobacterium flavescens (strain ATCC 700033 / PYR-GCK)
80	D5UTQ4_TSUPD (D5UTQ4)	2e-80	304	49%	UniProt GenBank	General substrate transporter	Tpau_0772	Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040) Corynebacterium paurometabolum
81	D9VFL7_9ACTO (D9VFL7)	3e-80	303	46%	UniProt GenBank	Major facilitator transporter	SSMG_03821	Streptomyces sp. AA4
82	Q5YVS7_NOCFA (Q5YVS7)	1e-79	301	49%	UniProt GenBank	Putative transporter	NFA_28670	Nocardia farcinica
83	Q1ATK6_RUBXD (Q1ATK6)	1e-79	301	51%	UniProt GenBank	Major facilitator superfamily MFS_1	Rxyl_2344	Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
84	Q5YY12_NOCFA (Q5YY12)	1e-79	301	48%	UniProt GenBank	Putative transporter	NFA_20830	Nocardia farcinica
85	Q1LD19_RALME (Q1LD19)	3e-79	300	46%	UniProt GenBank	Putative transporter protein, MFS family	Rmet_5098	Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)
86	B1FBJ8_9BURK (B1FBJ8)	4e-79	300	47%	UniProt GenBank	Major facilitator superfamily MFS_1	BamIOP4010DRAFT_1407	Burkholderia ambifaria IOP40-10
87	Q0B2H1_BURCM (Q0B2H1)	4e-79	300	47%	UniProt GenBank	Major facilitator superfamily MFS_1	Bamb_6108	Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) Burkholderia cepacia (strain AMMD)
88	B1T8F8_9BURK (B1T8F8)	5e-79	299	47%	UniProt GenBank	Major facilitator superfamily MFS_1	BamMEX5DRAFT_4074	Burkholderia ambifaria MEX-5
89	E4WBG0_RHOE1 (E4WBG0)	1e-78	298	46%	UniProt GenBank	Putative MFS transporter	REQ_01110	Rhodococcus equi (strain 103S) Corynebacterium equi
90	E9T7V4_COREQ (E9T7V4)	1e-78	298	46%	UniProt GenBank	MFS family major facilitator transporter	HMPREF0724_14860	Rhodococcus equi ATCC 33707
91	F0M6I4_ARTPP (F0M6I4)	2e-78	297	46%	UniProt GenBank	Sugar phosphate permease	Asphe3_13280	Arthrobacter phenanthrenivorans (strain DSM 18606 / JCM 16027 / LMG 23796 / Sphe3)
92	B1Z3J4_BURA4 (B1Z3J4)	5e-78	296	47%	UniProt GenBank	Major facilitator superfamily MFS_1	BamMC406_5869	Burkholderia ambifaria (strain MC40-6)
93	E0SEQ0_DICD3 (E0SEQ0)	8e-78	295	47%	UniProt GenBank	Transporter, MFS superfamily	Dda3937_02531	Dickeya dadantii (strain 3937) Erwinia chrysanthemi (strain 3937)
94	B8HB91_ARTCA (B8HB91)	8e-78	295	48%	UniProt GenBank	General substrate transporter	Achl_0577	Arthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360)
95	D2BZN3_DICD5 (D2BZN3)	1e-77	295	46%	UniProt GenBank	General substrate transporter	Dd586_4079	Dickeya dadantii (strain Ech586)
96	F0M9K9_ARTPP (F0M9K9)	1e-77	295	48%	UniProt GenBank	Sugar (And other) transporter	Asphe3_04710	Arthrobacter phenanthrenivorans (strain DSM 18606 / JCM 16027 / LMG 23796 / Sphe3)
97	Q0K770_CUPNH (Q0K770)	1e-77	295	49%	UniProt GenBank	MFS transporter, MHS family	H16_A3076	Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) Ralstonia eutropha
98	A1R1U2_ARTAT (A1R1U2)	2e-77	294	48%	UniProt GenBank	Putative major facilitator superfamily (MFS) transporter	AAur_0391	Arthrobacter aurescens (strain TC1)
99	C6CQ27_DICZE (C6CQ27)	8e-77	292	43%	UniProt GenBank	General substrate transporter	Dd1591_4107	Dickeya zeae (strain Ech1591)
100	C1AXG4_RHOOB (C1AXG4)	2e-76	291	47%	UniProt GenBank	Putative MFS transporter	ROP_14210	Rhodococcus opacus (strain B4)

accession

alignment

Evalue

Score

Ident.

link

information

pubmed

Q194R9_STRAA
(Q194R9)

0.0

820

100%

Product: Membrane protein
Gene
Organism: Streptomyces argillaceus

[pubmed all]
1uniprot[Pubmed] 8654997 [Medline] 96257259 Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144 An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479 Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047 Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 9882681 [Medline] 99102230 The mithramycin gene cluster of Streptomyces argillaceus contains a positive regulatory gene and two repeated DNA sequences that are located at both ends of the cluster.(J. Bacteriol.) [1999]
6uniprot[Pubmed] 10102355 [Medline] 99200478 Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
7uniprot[Pubmed] 9889148 [Medline] 99111236 Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
8uniprot[Pubmed] 10660060 [Medline] 20123456 Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
9uniprot[Pubmed] 11254130 [Medline] 21148776 The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
10uniprot[Pubmed] 12733914 [Medline] 22619809 Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
11uniprot[Pubmed] 9917296 [Medline] 99115752 The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
12uniprot[Pubmed] 11853433 [Medline] 21843297 Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
13uniprot[Pubmed] 10652287 [Medline] 20119254 Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
14uniprot[Pubmed] 10779713 [Medline] 20243461 Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
15uniprot[Pubmed] 12022840 [Medline] 22017994 Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
16uniprot[Pubmed] 12813091 [Medline] 22697398 Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
17uniprot[Pubmed] 8807845 [Medline] 97113238 Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
18uniprot[Pubmed] 14660589 MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
19uniprot[Pubmed] 9375253 [Medline] 98042823 Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
20uniprot[Pubmed] 15712316 Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
21uniprot[Pubmed] 10760873 The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]

A3KJW5_STRAM
(A3KJW5)

1e-163

578

83%

Product: Putative integral membrane transport protein
Gene: SAML1014
Organism: Streptomyces ambofaciens ATCC 23877

1uniprot[Pubmed] 16956972
Evolution of the terminal regions of the Streptomyces linear chromosome.(Mol. Biol. Evol.) [2006]

Q9EX30_STRCO
(Q9EX30)

1e-161

572

82%

Product: Putative integral membrane transport protein
Gene: SCO1010
Organism: Streptomyces coelicolor

1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]

Q82N85_STRAW
(Q82N85)

1e-159

567

83%

Product: Putative transporter
Gene: SAV1418
SAV_1418
Organism: Streptomyces avermitilis

1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]

F2R8P2_STRVP
(F2R8P2)

1e-153

546

81%

Product: Putative transporter
Gene: SVEN_0673
Organism: Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)

1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]

D7C879_STRBB
(D7C879)

1e-150

535

79%

Product: Transporter
Gene: SBI_01119
Organism: Streptomyces bingchenggensis (strain BCW-1)

1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]

B1VV41_STRGG
(B1VV41)

1e-126

456

66%

Product: Putative permease of the major facilitator superfamily
Gene: SGR_1196
Organism: Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)

1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]

D3PUT9_STANL
(D3PUT9)

1e-125

452

68%

Product: Major facilitator superfamily MFS_1
Gene: Snas_5329
Organism: Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)

1uniprot
Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009]

D7AZT9_NOCDD
(D7AZT9)

1e-123

447

65%

Product: Metabolite/H+ symporter, major facilitator superfamily (MFS)
Gene: Ndas_2798
Organism: Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei

1uniprot
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]

D8HN12_AMYMU
(D8HN12)

1e-119

433

65%

Product: Major facilitator transporter
Gene: AMED_5953
Organism: Amycolatopsis mediterranei (strain U-32)

1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]

E4N5Y4_KITSK
(E4N5Y4)

1e-119

431

62%

Product: Putative major facilitator superfamily transporter
Gene: KSE_07760
Organism: Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae

1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]

D2B2D2_STRRD
(D2B2D2)

1e-115

419

68%

Product: Putative transport protein
Gene: Sros_8515
Organism: Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)

1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]

E2Q1H3_STRCL
(E2Q1H3)

1e-111

405

63%

Product: Major facilitator superfamily permease
Gene: SCLAV_5532
Organism: Streptomyces clavuligerus ATCC 27064

1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]

C7MYB3_SACVD
(C7MYB3)

1e-110

404

62%

Product: Nitrate/nitrite transporter
Gene: Svir_10040
Organism: Saccharomonospora viridis (strain ATCC 15386 / DSM 43017 / JCM 3036 / NBRC 12207 / P101)

1uniprot
Complete genome sequence of Saccharomonospora viridis type strain (P101T).(Stand. Genomic Sci.) [2009]

A4FP75_SACEN
(A4FP75)

1e-107

394

63%

Product: Metabolite transporter, MFS superfamily
Gene: SACE_6684
Organism: Saccharopolyspora erythraea (strain NRRL 23338)

1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]

A4FG14_SACEN
(A4FG14)

1e-101

373

62%

Product: Integral membrane transport protein
Gene: SACE_3717
Organism: Saccharopolyspora erythraea (strain NRRL 23338)

1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]

Q0RZN0_RHOSR
(Q0RZN0)

1e-100

370

54%

Product: Probable metabolite transporter, MFS superfamily protein
Gene: RHA1_ro08211
Organism: Rhodococcus sp. (strain RHA1)

1uniprot[Pubmed] 17030794
The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse.(Proc. Natl. Acad. Sci. U.S.A.) [2006]

C7Q3V0_CATAD
(C7Q3V0)

3e-92

343

52%

Product: General substrate transporter
Gene: Caci_8895
Organism: Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)

1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]

Q0S9X9_RHOSR
(Q0S9X9)

3e-88

330

49%

Product: Metabolite transporter, MFS superfamily protein
Gene: RHA1_ro03857
Organism: Rhodococcus sp. (strain RHA1)

1uniprot[Pubmed] 17030794
The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse.(Proc. Natl. Acad. Sci. U.S.A.) [2006]

A3TNL2_9MICO
(A3TNL2)

7e-88

329

54%

Product: Putative integral membrane transport protein
Gene: JNB_14188
Organism: Janibacter sp. HTCC2649

1uniprot[Pubmed] 21075932
Genome sequence of the Marine Janibacter Sp. Strain HTCC2649.(J. Bacteriol.) [2011]

A4FGP1_SACEN
(A4FGP1)

1e-86

325

51%

Product: Metabolite transporter, MFS superfamily
Gene: SACE_3945
Organism: Saccharopolyspora erythraea (strain NRRL 23338)

1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]

Q89W04_BRAJA
(Q89W04)

5e-84

316

51%

Product: Bll0889 protein
Gene: bll0889
Organism: Bradyrhizobium japonicum

1uniprot[Pubmed] 12597275 [Medline] 22484998
Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110.(DNA Res.) [2002]

F2LLX1_BURGA
(F2LLX1)

3e-83

313

46%

Product: Major facilitator transporter
Gene: bgla_2g13710
Organism: Burkholderia gladioli BSR3

1uniprot[Pubmed] 21478339
Complete Genome Sequence of Burkholderia gladioli BSR3.(J. Bacteriol.) [2011]

C0ZWR5_RHOE4
(C0ZWR5)

8e-82

308

47%

Product: Putative MFS transporter
Gene: RER_20920
Organism: Rhodococcus erythropolis (strain PR4 / NBRC 100887)

1uniprot
Sequence analysis of three plasmids harboured in Rhodococcus erythropolis strain PR4.(Environ. Microbiol.) [2006]

Q0S7C2_RHOSR
(Q0S7C2)

9e-82

308

48%

Product: Metabolite transporter, MFS superfamily protein
Gene: RHA1_ro04779
Organism: Rhodococcus sp. (strain RHA1)

1uniprot[Pubmed] 17030794
The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse.(Proc. Natl. Acad. Sci. U.S.A.) [2006]

D3HS89_LEGLN
(D3HS89)

9e-81

305

47%

Product: Shikimate transporter
Gene: shiA
LLO_1408
Organism: Legionella longbeachae serogroup 1 (strain NSW150)

1uniprot[Pubmed] 20174605
Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease.(PLoS Genet.) [2010]

D1REY3_LEGLO
(D1REY3)

9e-81

305

47%

Product: Shikimate transporter
Gene: shiA
LLB_0246
Organism: Legionella longbeachae D-4968

1uniprot
The Genomic Sequence of the Soil-Dwelling Opportunistic Pathogen Legionella longbeachae.(J. Bacteriol.) [2010]

Q6JHP9_9PSEU
(Q6JHP9)

2e-80

304

46%

Product: Putative transporter
Gene
Organism: Saccharopolyspora spinosa

1uniprot[Pubmed] 15346767
Analysis of a 108-kb region of the Saccharopolyspora spinosa genome covering the obscurin polyketide synthase locus.(DNA Seq.) [2004]

Q5YVS7_NOCFA
(Q5YVS7)

1e-79

301

49%

Product: Putative transporter
Gene: NFA_28670
Organism: Nocardia farcinica

1uniprot[Pubmed] 15466710
The complete genomic sequence of Nocardia farcinica IFM 10152.(Proc. Natl. Acad. Sci. U.S.A.) [2004]

Q5YY12_NOCFA
(Q5YY12)

1e-79

301

48%

Product: Putative transporter
Gene: NFA_20830
Organism: Nocardia farcinica

1uniprot[Pubmed] 15466710
The complete genomic sequence of Nocardia farcinica IFM 10152.(Proc. Natl. Acad. Sci. U.S.A.) [2004]

E4WBG0_RHOE1
(E4WBG0)

1e-78

298

46%

Product: Putative MFS transporter
Gene: REQ_01110
Organism: Rhodococcus equi (strain 103S)
Corynebacterium equi

1uniprot[Pubmed] 20941392
The genome of a pathogenic rhodococcus: cooptive virulence underpinned by key gene acquisitions.(PLoS Genet.) [2010]

F0M6I4_ARTPP
(F0M6I4)

2e-78

297

46%

Product: Sugar phosphate permease
Gene: Asphe3_13280
Organism: Arthrobacter phenanthrenivorans (strain DSM 18606 / JCM 16027 / LMG 23796 / Sphe3)

1uniprot
Complete genome sequence of Arthrobacter phenanthrenivorans type strain (Sphe3T).(Stand. Genomic Sci.) [2011]

F0M9K9_ARTPP
(F0M9K9)

1e-77

295

48%

Product: Sugar (And other) transporter
Gene: Asphe3_04710
Organism: Arthrobacter phenanthrenivorans (strain DSM 18606 / JCM 16027 / LMG 23796 / Sphe3)

1uniprot
Complete genome sequence of Arthrobacter phenanthrenivorans type strain (Sphe3T).(Stand. Genomic Sci.) [2011]

Q0K770_CUPNH
(Q0K770)

1e-77

295

49%

Product: MFS transporter, MHS family
Gene: H16_A3076
Organism: Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
Ralstonia eutropha

1uniprot[Pubmed] 16964242
Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia eutropha H16.(Nat. Biotechnol.) [2006]

A1R1U2_ARTAT
(A1R1U2)

2e-77

294

48%

Product: Putative major facilitator superfamily (MFS) transporter
Gene: AAur_0391
Organism: Arthrobacter aurescens (strain TC1)

1uniprot[Pubmed] 17194220
Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1.(PLoS Genet.) [2006]