Cluster List

Last update : 2016-12-27

[ALL] A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Compound name	organism	activity
A40926	Nonomuraea sp. ATCC 39727	Antibacterial
A47934	Streptomyces toyocaensis NRRL 15009	Antibacterial
Aclacinomycin A	Streptomyces galilaeus ATCC 31615	Antitumor; Toxic
Actinorhodin	Streptomyces coelicolor A3(2) (=NBRC 15146)	Antibacterial; Organocatalysis
Alnumycin	Streptomyces sp. CM020	Antitumor; Gyrase inhibitory; Topoisomerase inhibitory
Alpha-lipomycin	Streptomyces aureofaciens Tu117	Antibacterial
Amphotericin B	Streptomyces nodosus ATCC 14899 (=NBRC 12895)	Antifungal
Ansamitocin	Actinosynnema pretiosum subsp. auranticum ATCC 31565	Antifungal; Antitumor
Aranciamycin	Streptomyces echinatus Tu303	Antibacterial; Collagenase inhibitor
Ascomycin	Streptomyces hygroscopicus subsp. ascomyceticus ATCC 14891 (=NBRC 13981)	Immunosuppressive; Antifungal
Aureothin	Streptomyces thioluteus HKI-227	Antitumor; Antifungal; Insecticidal
Avermectin	Streptomyces avermitilis ATCC 31267 (=NBRC 14893)	Anthelmintic
Avilamycin	Streptomyces viridochromogenes Tu57	Antibacterial
Azinomycin B	Streptomyces sahachiroi NRRL 2485 (=NBRC 13928)	Antitumor
Balhimycin	Amycolatopsis balhimycina DSM 5908	Antibacterial
Benastatin	Streptomyces sp. A2991200	Antibacterial; Apoptosis inducer; glutathione-S-transferase(GST) inhibitor
Borrelidin	Streptomyces parvulus Tu4055	Angiogenesis Inhibition; Antibacterial; Antiviral; Antiproliferative; Antiprotozoal
C-1027	Streptomyces globisporus C-1027	Antibiotic; Antitumor
Calicheamicin	Micromonospora echinospora NRRL 15839	Antibiotic; Antitumor
Chalcomycin	Streptomyces bikiniensis NRRL 2737	Antibacterial
Chartreusin	Streptomyces chartreusis HKI-249	Antibacterial; Antitumor
Chloroeremomycin	Amycolatopsis orientalis A82846UV37B	Antibacterial
Chlorothricin	Streptomyces antibioticus DSM 40725	Antibacterial
Chromomycin	Streptomyces griseus ATCC 13273 (=NBRC 3746)	Antibacterial; Antitumor; Antiviral
Concanamycin A	Streptomyces neyagawaensis ATCC 27449 (=NBRC 13477)	Antifungal; Antiprotozoal; Antitumor; Antiviral
Cosmomycin	Streptomyces olindensis DAUFPE 5622	Antitumor
Cryptophycin 1	Nostoc sp. ATCC 53789	Toxic
Daunorubicin	Streptomyces sp. C5	Antitumor
Doxorubicin	Streptomyces peucetius ATCC 29050 (=NBRC 100596)	Antitumor
Dynemicin	Micromonospora chersina ATCC 53710 (=NBRC 15963)	Antibiotic; Antitumor
Elloramycin	Streptomyces olivaceus Tu2353	Antibacterial; Antitumor
Enterocin	Streptomyces maritimus	Antibacterial
Epothilone	Sorangium cellulosum So ce90	Antitumor
FD-891	Streptomyces graminofaciens A-8890	Antitumor; Toxic
FR-008	Streptomyces sp. FR-008	Antifungal
Fredericamycin	Streptomyces griseus ATCC 49344	Antibacterial; Antifungal; Antitumor
Frenolicin	Streptomyces roseofulvus AK24158	Antibacterial; Antiprotozoal
Geldanamycin	Streptomyces hygroscopicus 17997	Antitumor; Antivirus
Geldanamycin	Streptomyces geldanamycininus NRRL 3602 (=NBRC 14620)	Antitumor; Antivirus
Gilvocarcin	Streptomyces griseoflavus Go 3592	Antibacterial; Antitumor; Antiviral
Granaticin	Streptomyces violaceoruber Tu22	Antibacterial
Griseorhodin A	Streptomyces sp. JP95	Antibacterial; human telomerase inhibitor
Griseusin	Streptomyces griseus K-63	Antibacterial
Halstoctacosanolide	Streptomyces halstedii HC34	Antibacterial
Hectochlorin	Lyngbya majuscula JHB	Antifungal; Antitumor; Toxic
Hedamycin	Streptomyces griseoruber ATCC 15422	Antitumor
Herbimycin A	Streptomyces hygroscopicus AM 3672	Antitumor
Indanomycin	Streptomyces antibioticus NRRL 8167	Antibacterial; Antiprotozoal; Insecticidal; Ionophore
Jadomycin B	Streptomyces venezuelae ISP5230 (=NBRC 13096)	Antibacterial
Kirromycin	Streptomyces collinus Tu365	Antibacterial
Landomycin	Streptomyces cyanogenus S136	Antitumor
Lasalocid	Streptomyces lasaliensis ATCC 35851	Antibacterial; Ionophore
Lasalocid	Streptomyces lasaliensis ATCC 31180	Antibacterial; Ionophore
Lydicamycin	Streptomyces sp. TP-A0598 (=NBRC 110027)	Antibacterial
Maduropeptin	Actinomadura madurae ATCC 39144	Antibiotic; Antitumor
Medermycin	Streptomyces sp. AM-7161	Antibacterial; Antitumor
Megalomicin	Micromonospora megalomicea subsp. nigra NRRL 3275 (=NBRC 14744)	Antibacterial; Antiparasitic; Antiviral
Meilingmycin	Streptomyces nanchangensis NS3226	Anthelmintic
Meridamycin	Streptomyces violaceusniger DSM 4137	Neuroprotective; Non-immunosuppressive
Mithramycin	Streptomyces argillaceus ATCC 12956	Antibacterial; Antitumor
Monensin	Streptomyces cinnamonensis ATCC 15413	Antibacterial; Ionophore; Antiprotozoal
Mycolactone	Mycobacterium ulcerans Agy99	Toxic; Immunosuppressive
Myxalamid	Stigmatella aurantiaca Sga15	Antifungal; Antibacterial
Myxothiazol	Stigmatella aurantiaca DW4/3-1	Antifungal
Nanchangmycin	Streptomyces nanchangensis NS3226	Antibacterial; Insecticidal; Ionophore
Naphthocyclinone	Streptomyces arenae DSM 40737	Antibacterial
Neocarzinostatin	Streptomyces carzinostaticus ATCC 15944	Antibiotic; Antitumor
Niddamycin	Streptomyces caelestis NRRL 2821	Antibacterial
Nigericin	Streptomyces violaceusniger DSM 4137	Antibacterial; Ionophore
Nogalamycin	Streptomyces nogalater ATCC 27451 (=NBRC 13445)	Antibacterial; Antitumor; Toxic
Nystatin	Streptomyces noursei ATCC 11455 (=NBRC 15452)	Antifungal
Oligomycin	Streptomyces avermitilis ATCC 31267 (=NBRC 14893)	Antifungal; Toxic; Antitumor
Oviedomycin	Streptomyces antibioticus ATCC 11891	Antitumor
Oxazolomycin	Streptomyces albus JA3453	Antibacterial; Antitumor; Antivirus; Ionophore
Oxytetracycline	Streptomyces rimosus ATCC 10970 (=NBRC 12907)	Antibacterial
Pactamycin	Streptomyces pactum ATCC 27456 (=NBRC 13433)	Antibacterial; Antiprotozoal; Antitumor; Antiviral; Toxic
Phoslactomycin	Streptomyces sp. HK803	Antifungal; Antitumor
Piericidin	Streptomyces piomogenus var. Hangzhouwanensis	Antibacterial; Antifungal; Antitumor
Pikromycin	Streptomyces venezuelae ATCC 15439	Antibacterial
Pimaricin	Streptomyces natalensis ATCC 27448 (=NBRC 13367)	Antifungal
Pladienolide	Streptomyces platensis Mer-11107	Antitumor
Polyketomycin	Streptomyces diastatochromogenes Tu6028	Antibacterial; Antitumor
Pyoluteorin	Pseudomonas fluorescens Pf-5	Antibacterial; Antifungal
Pyrrolomycin	Actinosporangium vitaminophilum ATCC 31673 (=NBRC 14294)	Antibacterial [A, B, C, D, E]; Antifungal [A, B, D]; Immunopotentiator [B]; Toxic [C, D]
R1128	Streptomyces sp. R1128	Estrogen receptor antagonist
Rapamycin	Streptomyces rapamycinicus NRRL 5491	Immunosuppressive; Antitumor; Neuroprotective; Antiaging
Resistomycin	Streptomyces resistomycificus HKI-237	Antibacterial; Antiviral
Reveromycin	Streptomyces sp. SN-593	Antifungal; Antiosteoclastic
Rifamycin	Amycolatopsis mediterranei S699	Antibacterial
Rimocidin	Streptomyces diastaticus 108	Antifungal
Rubradirin	Streptomyces achromogenes var. rubradiris NRRL 3061 (=NBRC 14000)	Antibacterial
Salinomycin	Streptomyces albus subsp. albus DSM 41398	Antibacterial; Antiprotozoal; Antitumor; Ionophore
Salinomycin	Streptomyces albus XM211	Antibacterial; Antiprotozoal; Antitumor; Ionophore
Sch 47554	Streptomyces sp. SCC-2136	Antifungal
Soraphen	Sorangium cellulosum So ce26	Antifungal
Spinosyn	Saccharopolyspora spinosa NRRL 18538	Insecticidal
Steffimycin	Streptomyces steffisburgensis NRRL 3193 (=NBRC 13446)	Antitumor
Stigmatellin	Stigmatella aurantiaca Sga15	Antifungal
Streptolydigin	Streptomyces lydicus NRRL 2433 (=NBRC 13058)	Antibacterial
Tautomycetin	Streptomyces sp. CK4412	Antifungal; Antitumor; Immunosuppressive
Tautomycin	Streptomyces spiroverticillatus	Antibacterial; Antifungal; Antitumor
Teicoplanin	Actinoplanes teichomyceticus DSM 43866 (=NBRC 13999)	Antibacterial
Teicoplanin	Actinoplanes teichomyceticus ATCC 31121 (=NBRC 13999)	Antibacterial
Tetronomycin	Streptomyces sp. NRRL 11266	Antibacterial; Ionophore
Urdamycin	Streptomyces fradiae Tu2717	Antibacterial; Antitumor
Vancomycin	Amycolatopsis orientalis ATCC 19795 (=NBRC 12806)	Antibacterial
Vicenistatin	Streptomyces halstedii HC34	Antitumor
Virginiamycin	Streptomyces virginiae MAFF 10-06014	Antibacterial

Compound name	organism	activity
TypeI modular
Amphotericin B	Streptomyces nodosus ATCC 14899 (=NBRC 12895)	Antifungal
Ansamitocin	Actinosynnema pretiosum subsp. auranticum ATCC 31565	Antifungal; Antitumor
Avermectin	Streptomyces avermitilis ATCC 31267 (=NBRC 14893)	Anthelmintic
Chalcomycin	Streptomyces bikiniensis NRRL 2737	Antibacterial
Chlorothricin	Streptomyces antibioticus DSM 40725	Antibacterial
Concanamycin A	Streptomyces neyagawaensis ATCC 27449 (=NBRC 13477)	Antifungal; Antiprotozoal; Antitumor; Antiviral
FD-891	Streptomyces graminofaciens A-8890	Antitumor; Toxic
FR-008	Streptomyces sp. FR-008	Antifungal
Geldanamycin	Streptomyces hygroscopicus 17997	Antitumor; Antivirus
Geldanamycin	Streptomyces geldanamycininus NRRL 3602 (=NBRC 14620)	Antitumor; Antivirus
Halstoctacosanolide	Streptomyces halstedii HC34	Antibacterial
Hedamycin	Streptomyces griseoruber ATCC 15422	Antitumor
Herbimycin A	Streptomyces hygroscopicus AM 3672	Antitumor
Lasalocid	Streptomyces lasaliensis ATCC 35851	Antibacterial; Ionophore
Lasalocid	Streptomyces lasaliensis ATCC 31180	Antibacterial; Ionophore
Megalomicin	Micromonospora megalomicea subsp. nigra NRRL 3275 (=NBRC 14744)	Antibacterial; Antiparasitic; Antiviral
Meilingmycin	Streptomyces nanchangensis NS3226	Anthelmintic
Monensin	Streptomyces cinnamonensis ATCC 15413	Antibacterial; Ionophore; Antiprotozoal
Mycolactone	Mycobacterium ulcerans Agy99	Toxic; Immunosuppressive
Nanchangmycin	Streptomyces nanchangensis NS3226	Antibacterial; Insecticidal; Ionophore
Niddamycin	Streptomyces caelestis NRRL 2821	Antibacterial
Nigericin	Streptomyces violaceusniger DSM 4137	Antibacterial; Ionophore
Nystatin	Streptomyces noursei ATCC 11455 (=NBRC 15452)	Antifungal
Oligomycin	Streptomyces avermitilis ATCC 31267 (=NBRC 14893)	Antifungal; Toxic; Antitumor
Phoslactomycin	Streptomyces sp. HK803	Antifungal; Antitumor
Piericidin	Streptomyces piomogenus var. Hangzhouwanensis	Antibacterial; Antifungal; Antitumor
Pikromycin	Streptomyces venezuelae ATCC 15439	Antibacterial
Pimaricin	Streptomyces natalensis ATCC 27448 (=NBRC 13367)	Antifungal
Pladienolide	Streptomyces platensis Mer-11107	Antitumor
Reveromycin	Streptomyces sp. SN-593	Antifungal; Antiosteoclastic
Rifamycin	Amycolatopsis mediterranei S699	Antibacterial
Rimocidin	Streptomyces diastaticus 108	Antifungal
Rubradirin	Streptomyces achromogenes var. rubradiris NRRL 3061 (=NBRC 14000)	Antibacterial
Salinomycin	Streptomyces albus subsp. albus DSM 41398	Antibacterial; Antiprotozoal; Antitumor; Ionophore
Salinomycin	Streptomyces albus XM211	Antibacterial; Antiprotozoal; Antitumor; Ionophore
Soraphen	Sorangium cellulosum So ce26	Antifungal
Spinosyn	Saccharopolyspora spinosa NRRL 18538	Insecticidal
Tautomycetin	Streptomyces sp. CK4412	Antifungal; Antitumor; Immunosuppressive
Tautomycin	Streptomyces spiroverticillatus	Antibacterial; Antifungal; Antitumor
Tetronomycin	Streptomyces sp. NRRL 11266	Antibacterial; Ionophore
Vicenistatin	Streptomyces halstedii HC34	Antitumor
TypeI iterative
Aureothin	Streptomyces thioluteus HKI-227	Antitumor; Antifungal; Insecticidal
Avilamycin	Streptomyces viridochromogenes Tu57	Antibacterial
Borrelidin	Streptomyces parvulus Tu4055	Angiogenesis Inhibition; Antibacterial; Antiviral; Antiproliferative; Antiprotozoal
C-1027	Streptomyces globisporus C-1027	Antibiotic; Antitumor
Calicheamicin	Micromonospora echinospora NRRL 15839	Antibiotic; Antitumor
Chlorothricin	Streptomyces antibioticus DSM 40725	Antibacterial
Dynemicin	Micromonospora chersina ATCC 53710 (=NBRC 15963)	Antibiotic; Antitumor
Maduropeptin	Actinomadura madurae ATCC 39144	Antibiotic; Antitumor
Neocarzinostatin	Streptomyces carzinostaticus ATCC 15944	Antibiotic; Antitumor
Pactamycin	Streptomyces pactum ATCC 27456 (=NBRC 13433)	Antibacterial; Antiprotozoal; Antitumor; Antiviral; Toxic
Polyketomycin	Streptomyces diastatochromogenes Tu6028	Antibacterial; Antitumor
Stigmatellin	Stigmatella aurantiaca Sga15	Antifungal
Trans-AT
Kirromycin	Streptomyces collinus Tu365	Antibacterial
Oxazolomycin	Streptomyces albus JA3453	Antibacterial; Antitumor; Antivirus; Ionophore
Virginiamycin	Streptomyces virginiae MAFF 10-06014	Antibacterial
TypeII
Aclacinomycin A	Streptomyces galilaeus ATCC 31615	Antitumor; Toxic
Actinorhodin	Streptomyces coelicolor A3(2) (=NBRC 15146)	Antibacterial; Organocatalysis
Alnumycin	Streptomyces sp. CM020	Antitumor; Gyrase inhibitory; Topoisomerase inhibitory
Aranciamycin	Streptomyces echinatus Tu303	Antibacterial; Collagenase inhibitor
Benastatin	Streptomyces sp. A2991200	Antibacterial; Apoptosis inducer; glutathione-S-transferase(GST) inhibitor
Chartreusin	Streptomyces chartreusis HKI-249	Antibacterial; Antitumor
Chromomycin	Streptomyces griseus ATCC 13273 (=NBRC 3746)	Antibacterial; Antitumor; Antiviral
Cosmomycin	Streptomyces olindensis DAUFPE 5622	Antitumor
Daunorubicin	Streptomyces sp. C5	Antitumor
Doxorubicin	Streptomyces peucetius ATCC 29050 (=NBRC 100596)	Antitumor
Elloramycin	Streptomyces olivaceus Tu2353	Antibacterial; Antitumor
Enterocin	Streptomyces maritimus	Antibacterial
Fredericamycin	Streptomyces griseus ATCC 49344	Antibacterial; Antifungal; Antitumor
Frenolicin	Streptomyces roseofulvus AK24158	Antibacterial; Antiprotozoal
Gilvocarcin	Streptomyces griseoflavus Go 3592	Antibacterial; Antitumor; Antiviral
Granaticin	Streptomyces violaceoruber Tu22	Antibacterial
Griseorhodin A	Streptomyces sp. JP95	Antibacterial; human telomerase inhibitor
Griseusin	Streptomyces griseus K-63	Antibacterial
Hedamycin	Streptomyces griseoruber ATCC 15422	Antitumor
Jadomycin B	Streptomyces venezuelae ISP5230 (=NBRC 13096)	Antibacterial
Landomycin	Streptomyces cyanogenus S136	Antitumor
Medermycin	Streptomyces sp. AM-7161	Antibacterial; Antitumor
Mithramycin	Streptomyces argillaceus ATCC 12956	Antibacterial; Antitumor
Naphthocyclinone	Streptomyces arenae DSM 40737	Antibacterial
Nogalamycin	Streptomyces nogalater ATCC 27451 (=NBRC 13445)	Antibacterial; Antitumor; Toxic
Oviedomycin	Streptomyces antibioticus ATCC 11891	Antitumor
Oxytetracycline	Streptomyces rimosus ATCC 10970 (=NBRC 12907)	Antibacterial
Polyketomycin	Streptomyces diastatochromogenes Tu6028	Antibacterial; Antitumor
R1128	Streptomyces sp. R1128	Estrogen receptor antagonist
Resistomycin	Streptomyces resistomycificus HKI-237	Antibacterial; Antiviral
Sch 47554	Streptomyces sp. SCC-2136	Antifungal
Steffimycin	Streptomyces steffisburgensis NRRL 3193 (=NBRC 13446)	Antitumor
Urdamycin	Streptomyces fradiae Tu2717	Antibacterial; Antitumor
PKS-NRPS hybrid
Alpha-lipomycin	Streptomyces aureofaciens Tu117	Antibacterial
Ascomycin	Streptomyces hygroscopicus subsp. ascomyceticus ATCC 14891 (=NBRC 13981)	Immunosuppressive; Antifungal
Cryptophycin 1	Nostoc sp. ATCC 53789	Toxic
Epothilone	Sorangium cellulosum So ce90	Antitumor
Hectochlorin	Lyngbya majuscula JHB	Antifungal; Antitumor; Toxic
Indanomycin	Streptomyces antibioticus NRRL 8167	Antibacterial; Antiprotozoal; Insecticidal; Ionophore
Kirromycin	Streptomyces collinus Tu365	Antibacterial
Lydicamycin	Streptomyces sp. TP-A0598 (=NBRC 110027)	Antibacterial
Meridamycin	Streptomyces violaceusniger DSM 4137	Neuroprotective; Non-immunosuppressive
Myxalamid	Stigmatella aurantiaca Sga15	Antifungal; Antibacterial
Myxothiazol	Stigmatella aurantiaca DW4/3-1	Antifungal
Oxazolomycin	Streptomyces albus JA3453	Antibacterial; Antitumor; Antivirus; Ionophore
Pyoluteorin	Pseudomonas fluorescens Pf-5	Antibacterial; Antifungal
Pyrrolomycin	Actinosporangium vitaminophilum ATCC 31673 (=NBRC 14294)	Antibacterial [A, B, C, D, E]; Antifungal [A, B, D]; Immunopotentiator [B]; Toxic [C, D]
Rapamycin	Streptomyces rapamycinicus NRRL 5491	Immunosuppressive; Antitumor; Neuroprotective; Antiaging
Streptolydigin	Streptomyces lydicus NRRL 2433 (=NBRC 13058)	Antibacterial
Virginiamycin	Streptomyces virginiae MAFF 10-06014	Antibacterial
NRPS
A40926	Nonomuraea sp. ATCC 39727	Antibacterial
A47934	Streptomyces toyocaensis NRRL 15009	Antibacterial
Azinomycin B	Streptomyces sahachiroi NRRL 2485 (=NBRC 13928)	Antitumor
Balhimycin	Amycolatopsis balhimycina DSM 5908	Antibacterial
C-1027	Streptomyces globisporus C-1027	Antibiotic; Antitumor
Chloroeremomycin	Amycolatopsis orientalis A82846UV37B	Antibacterial
Maduropeptin	Actinomadura madurae ATCC 39144	Antibiotic; Antitumor
Teicoplanin	Actinoplanes teichomyceticus DSM 43866 (=NBRC 13999)	Antibacterial
Teicoplanin	Actinoplanes teichomyceticus ATCC 31121 (=NBRC 13999)	Antibacterial
Vancomycin	Amycolatopsis orientalis ATCC 19795 (=NBRC 12806)	Antibacterial
Virginiamycin	Streptomyces virginiae MAFF 10-06014	Antibacterial
other
A40926	Nonomuraea sp. ATCC 39727	Antibacterial
A47934	Streptomyces toyocaensis NRRL 15009	Antibacterial
Balhimycin	Amycolatopsis balhimycina DSM 5908	Antibacterial
Chloroeremomycin	Amycolatopsis orientalis A82846UV37B	Antibacterial
Teicoplanin	Actinoplanes teichomyceticus DSM 43866 (=NBRC 13999)	Antibacterial
Teicoplanin	Actinoplanes teichomyceticus ATCC 31121 (=NBRC 13999)	Antibacterial
Vancomycin	Amycolatopsis orientalis ATCC 19795 (=NBRC 12806)	Antibacterial

Compound name	organism	activity
acetyl-CoA
Aranciamycin	Streptomyces echinatus Tu303	Antibacterial; Collagenase inhibitor
Avilamycin	Streptomyces viridochromogenes Tu57	Antibacterial
Azinomycin B	Streptomyces sahachiroi NRRL 2485 (=NBRC 13928)	Antitumor
C-1027	Streptomyces globisporus C-1027	Antibiotic; Antitumor
Calicheamicin	Micromonospora echinospora NRRL 15839	Antibiotic; Antitumor
Chartreusin	Streptomyces chartreusis HKI-249	Antibacterial; Antitumor
Chlorothricin	Streptomyces antibioticus DSM 40725	Antibacterial
Chromomycin	Streptomyces griseus ATCC 13273 (=NBRC 3746)	Antibacterial; Antitumor; Antiviral
Dynemicin	Micromonospora chersina ATCC 53710 (=NBRC 15963)	Antibiotic; Antitumor
Elloramycin	Streptomyces olivaceus Tu2353	Antibacterial; Antitumor
Epothilone	Sorangium cellulosum So ce90	Antitumor
Gilvocarcin	Streptomyces griseoflavus Go 3592	Antibacterial; Antitumor; Antiviral
Griseorhodin A	Streptomyces sp. JP95	Antibacterial; human telomerase inhibitor
Jadomycin B	Streptomyces venezuelae ISP5230 (=NBRC 13096)	Antibacterial
Kirromycin	Streptomyces collinus Tu365	Antibacterial
Landomycin	Streptomyces cyanogenus S136	Antitumor
Maduropeptin	Actinomadura madurae ATCC 39144	Antibiotic; Antitumor
Mithramycin	Streptomyces argillaceus ATCC 12956	Antibacterial; Antitumor
Myxalamid	Stigmatella aurantiaca Sga15	Antifungal; Antibacterial
Neocarzinostatin	Streptomyces carzinostaticus ATCC 15944	Antibiotic; Antitumor
Nogalamycin	Streptomyces nogalater ATCC 27451 (=NBRC 13445)	Antibacterial; Antitumor; Toxic
Nystatin	Streptomyces noursei ATCC 11455 (=NBRC 15452)	Antifungal
Oviedomycin	Streptomyces antibioticus ATCC 11891	Antitumor
Pactamycin	Streptomyces pactum ATCC 27456 (=NBRC 13433)	Antibacterial; Antiprotozoal; Antitumor; Antiviral; Toxic
Piericidin	Streptomyces piomogenus var. Hangzhouwanensis	Antibacterial; Antifungal; Antitumor
Pimaricin	Streptomyces natalensis ATCC 27448 (=NBRC 13367)	Antifungal
Rimocidin	Streptomyces diastaticus 108	Antifungal
Sch 47554	Streptomyces sp. SCC-2136	Antifungal
Steffimycin	Streptomyces steffisburgensis NRRL 3193 (=NBRC 13446)	Antitumor
Stigmatellin	Stigmatella aurantiaca Sga15	Antifungal
Urdamycin	Streptomyces fradiae Tu2717	Antibacterial; Antitumor
malonyl-CoA
A40926	Nonomuraea sp. ATCC 39727	Antibacterial
A47934	Streptomyces toyocaensis NRRL 15009	Antibacterial
Actinorhodin	Streptomyces coelicolor A3(2) (=NBRC 15146)	Antibacterial; Organocatalysis
Amphotericin B	Streptomyces nodosus ATCC 14899 (=NBRC 12895)	Antifungal
Balhimycin	Amycolatopsis balhimycina DSM 5908	Antibacterial
Chalcomycin	Streptomyces bikiniensis NRRL 2737	Antibacterial
Chloroeremomycin	Amycolatopsis orientalis A82846UV37B	Antibacterial
Chlorothricin	Streptomyces antibioticus DSM 40725	Antibacterial
Concanamycin A	Streptomyces neyagawaensis ATCC 27449 (=NBRC 13477)	Antifungal; Antiprotozoal; Antitumor; Antiviral
FD-891	Streptomyces graminofaciens A-8890	Antitumor; Toxic
Granaticin	Streptomyces violaceoruber Tu22	Antibacterial
Lasalocid	Streptomyces lasaliensis ATCC 35851	Antibacterial; Ionophore
Lasalocid	Streptomyces lasaliensis ATCC 31180	Antibacterial; Ionophore
Medermycin	Streptomyces sp. AM-7161	Antibacterial; Antitumor
Meilingmycin	Streptomyces nanchangensis NS3226	Anthelmintic
Meridamycin	Streptomyces violaceusniger DSM 4137	Neuroprotective; Non-immunosuppressive
Monensin	Streptomyces cinnamonensis ATCC 15413	Antibacterial; Ionophore; Antiprotozoal
Mycolactone	Mycobacterium ulcerans Agy99	Toxic; Immunosuppressive
Nanchangmycin	Streptomyces nanchangensis NS3226	Antibacterial; Insecticidal; Ionophore
Naphthocyclinone	Streptomyces arenae DSM 40737	Antibacterial
Niddamycin	Streptomyces caelestis NRRL 2821	Antibacterial
Nigericin	Streptomyces violaceusniger DSM 4137	Antibacterial; Ionophore
Oligomycin	Streptomyces avermitilis ATCC 31267 (=NBRC 14893)	Antifungal; Toxic; Antitumor
Resistomycin	Streptomyces resistomycificus HKI-237	Antibacterial; Antiviral
Salinomycin	Streptomyces albus subsp. albus DSM 41398	Antibacterial; Antiprotozoal; Antitumor; Ionophore
Salinomycin	Streptomyces albus XM211	Antibacterial; Antiprotozoal; Antitumor; Ionophore
Streptolydigin	Streptomyces lydicus NRRL 2433 (=NBRC 13058)	Antibacterial
Tautomycetin	Streptomyces sp. CK4412	Antifungal; Antitumor; Immunosuppressive
Teicoplanin	Actinoplanes teichomyceticus DSM 43866 (=NBRC 13999)	Antibacterial
Teicoplanin	Actinoplanes teichomyceticus ATCC 31121 (=NBRC 13999)	Antibacterial
Tetronomycin	Streptomyces sp. NRRL 11266	Antibacterial; Ionophore
Vancomycin	Amycolatopsis orientalis ATCC 19795 (=NBRC 12806)	Antibacterial
propionyl-CoA
Aclacinomycin A	Streptomyces galilaeus ATCC 31615	Antitumor; Toxic
Cosmomycin	Streptomyces olindensis DAUFPE 5622	Antitumor
Daunorubicin	Streptomyces sp. C5	Antitumor
Doxorubicin	Streptomyces peucetius ATCC 29050 (=NBRC 100596)	Antitumor
Gilvocarcin	Streptomyces griseoflavus Go 3592	Antibacterial; Antitumor; Antiviral
Megalomicin	Micromonospora megalomicea subsp. nigra NRRL 3275 (=NBRC 14744)	Antibacterial; Antiparasitic; Antiviral
Myxalamid	Stigmatella aurantiaca Sga15	Antifungal; Antibacterial
methylmalonyl-CoA
Halstoctacosanolide	Streptomyces halstedii HC34	Antibacterial
Meilingmycin	Streptomyces nanchangensis NS3226	Anthelmintic
Pikromycin	Streptomyces venezuelae ATCC 15439	Antibacterial
Pladienolide	Streptomyces platensis Mer-11107	Antitumor
Reveromycin	Streptomyces sp. SN-593	Antifungal; Antiosteoclastic
Spinosyn	Saccharopolyspora spinosa NRRL 18538	Insecticidal
butyryl-ACP
Alnumycin	Streptomyces sp. CM020	Antitumor; Gyrase inhibitory; Topoisomerase inhibitory
Frenolicin	Streptomyces roseofulvus AK24158	Antibacterial; Antiprotozoal
R1128	Streptomyces sp. R1128	Estrogen receptor antagonist
isobutyryl-CoA
Alpha-lipomycin	Streptomyces aureofaciens Tu117	Antibacterial
Avermectin	Streptomyces avermitilis ATCC 31267 (=NBRC 14893)	Anthelmintic
Myxalamid	Stigmatella aurantiaca Sga15	Antifungal; Antibacterial
Tautomycin	Streptomyces spiroverticillatus	Antibacterial; Antifungal; Antitumor
Virginiamycin	Streptomyces virginiae MAFF 10-06014	Antibacterial
2-methylbutyryl-CoA
Avermectin	Streptomyces avermitilis ATCC 31267 (=NBRC 14893)	Anthelmintic
Myxalamid	Stigmatella aurantiaca Sga15	Antifungal; Antibacterial
hexanoyl-ACP
Benastatin	Streptomyces sp. A2991200	Antibacterial; Apoptosis inducer; glutathione-S-transferase(GST) inhibitor
R1128	Streptomyces sp. R1128	Estrogen receptor antagonist
benzoyl-CoA
Enterocin	Streptomyces maritimus	Antibacterial
Soraphen	Sorangium cellulosum So ce26	Antifungal
3-amino-5-hydroxybenzoic acid (AHBA)
Ansamitocin	Actinosynnema pretiosum subsp. auranticum ATCC 31565	Antifungal; Antitumor
Geldanamycin	Streptomyces hygroscopicus 17997	Antitumor; Antivirus
Geldanamycin	Streptomyces geldanamycininus NRRL 3602 (=NBRC 14620)	Antitumor; Antivirus
Herbimycin A	Streptomyces hygroscopicus AM 3672	Antitumor
Rifamycin	Amycolatopsis mediterranei S699	Antibacterial
Rubradirin	Streptomyces achromogenes var. rubradiris NRRL 3061 (=NBRC 14000)	Antibacterial
4,5-dihydroxycyclohex-1-ene carboxylic acid
Ascomycin	Streptomyces hygroscopicus subsp. ascomyceticus ATCC 14891 (=NBRC 13981)	Immunosuppressive; Antifungal
Rapamycin	Streptomyces rapamycinicus NRRL 5491	Immunosuppressive; Antitumor; Neuroprotective; Antiaging
L-proline
Indanomycin	Streptomyces antibioticus NRRL 8167	Antibacterial; Antiprotozoal; Insecticidal; Ionophore
Pyoluteorin	Pseudomonas fluorescens Pf-5	Antibacterial; Antifungal
Pyrrolomycin	Actinosporangium vitaminophilum ATCC 31673 (=NBRC 14294)	Antibacterial [A, B, C, D, E]; Antifungal [A, B, D]; Immunopotentiator [B]; Toxic [C, D]
other
Aureothin	Streptomyces thioluteus HKI-227	Antitumor; Antifungal; Insecticidal
Borrelidin	Streptomyces parvulus Tu4055	Angiogenesis Inhibition; Antibacterial; Antiviral; Antiproliferative; Antiprotozoal
Cryptophycin 1	Nostoc sp. ATCC 53789	Toxic
FR-008	Streptomyces sp. FR-008	Antifungal
Fredericamycin	Streptomyces griseus ATCC 49344	Antibacterial; Antifungal; Antitumor
Griseusin	Streptomyces griseus K-63	Antibacterial
Hectochlorin	Lyngbya majuscula JHB	Antifungal; Antitumor; Toxic
Hedamycin	Streptomyces griseoruber ATCC 15422	Antitumor
Lydicamycin	Streptomyces sp. TP-A0598 (=NBRC 110027)	Antibacterial
Myxothiazol	Stigmatella aurantiaca DW4/3-1	Antifungal
Oxazolomycin	Streptomyces albus JA3453	Antibacterial; Antitumor; Antivirus; Ionophore
Oxytetracycline	Streptomyces rimosus ATCC 10970 (=NBRC 12907)	Antibacterial
Phoslactomycin	Streptomyces sp. HK803	Antifungal; Antitumor
Polyketomycin	Streptomyces diastatochromogenes Tu6028	Antibacterial; Antitumor
R1128	Streptomyces sp. R1128	Estrogen receptor antagonist
Rimocidin	Streptomyces diastaticus 108	Antifungal
Vicenistatin	Streptomyces halstedii HC34	Antitumor
Virginiamycin	Streptomyces virginiae MAFF 10-06014	Antibacterial

Compound name	organism	activity
3
Pyoluteorin	Pseudomonas fluorescens Pf-5	Antibacterial; Antifungal
Pyrrolomycin	Actinosporangium vitaminophilum ATCC 31673 (=NBRC 14294)	Antibacterial [A, B, C, D, E]; Antifungal [A, B, D]; Immunopotentiator [B]; Toxic [C, D]
4
A40926	Nonomuraea sp. ATCC 39727	Antibacterial
A47934	Streptomyces toyocaensis NRRL 15009	Antibacterial
Avilamycin	Streptomyces viridochromogenes Tu57	Antibacterial
Balhimycin	Amycolatopsis balhimycina DSM 5908	Antibacterial
Calicheamicin	Micromonospora echinospora NRRL 15839	Antibiotic; Antitumor
Chloroeremomycin	Amycolatopsis orientalis A82846UV37B	Antibacterial
Chlorothricin	Streptomyces antibioticus DSM 40725	Antibacterial
Cryptophycin 1	Nostoc sp. ATCC 53789	Toxic
Maduropeptin	Actinomadura madurae ATCC 39144	Antibiotic; Antitumor
Pactamycin	Streptomyces pactum ATCC 27456 (=NBRC 13433)	Antibacterial; Antiprotozoal; Antitumor; Antiviral; Toxic
Polyketomycin	Streptomyces diastatochromogenes Tu6028	Antibacterial; Antitumor
Teicoplanin	Actinoplanes teichomyceticus DSM 43866 (=NBRC 13999)	Antibacterial
Teicoplanin	Actinoplanes teichomyceticus ATCC 31121 (=NBRC 13999)	Antibacterial
Vancomycin	Amycolatopsis orientalis ATCC 19795 (=NBRC 12806)	Antibacterial
6
Aureothin	Streptomyces thioluteus HKI-227	Antitumor; Antifungal; Insecticidal
Azinomycin B	Streptomyces sahachiroi NRRL 2485 (=NBRC 13928)	Antitumor
Hectochlorin	Lyngbya majuscula JHB	Antifungal; Antitumor; Toxic
Myxothiazol	Stigmatella aurantiaca DW4/3-1	Antifungal
Neocarzinostatin	Streptomyces carzinostaticus ATCC 15944	Antibiotic; Antitumor
7
Megalomicin	Micromonospora megalomicea subsp. nigra NRRL 3275 (=NBRC 14744)	Antibacterial; Antiparasitic; Antiviral
Pikromycin	Streptomyces venezuelae ATCC 15439	Antibacterial
Rubradirin	Streptomyces achromogenes var. rubradiris NRRL 3061 (=NBRC 14000)	Antibacterial
Virginiamycin	Streptomyces virginiae MAFF 10-06014	Antibacterial
8
Actinorhodin	Streptomyces coelicolor A3(2) (=NBRC 15146)	Antibacterial; Organocatalysis
Alnumycin	Streptomyces sp. CM020	Antitumor; Gyrase inhibitory; Topoisomerase inhibitory
Alpha-lipomycin	Streptomyces aureofaciens Tu117	Antibacterial
Ansamitocin	Actinosynnema pretiosum subsp. auranticum ATCC 31565	Antifungal; Antitumor
C-1027	Streptomyces globisporus C-1027	Antibiotic; Antitumor
Calicheamicin	Micromonospora echinospora NRRL 15839	Antibiotic; Antitumor
Chalcomycin	Streptomyces bikiniensis NRRL 2737	Antibacterial
Dynemicin	Micromonospora chersina ATCC 53710 (=NBRC 15963)	Antibiotic; Antitumor
Enterocin	Streptomyces maritimus	Antibacterial
Frenolicin	Streptomyces roseofulvus AK24158	Antibacterial; Antiprotozoal
Geldanamycin	Streptomyces hygroscopicus 17997	Antitumor; Antivirus
Geldanamycin	Streptomyces geldanamycininus NRRL 3602 (=NBRC 14620)	Antitumor; Antivirus
Granaticin	Streptomyces violaceoruber Tu22	Antibacterial
Herbimycin A	Streptomyces hygroscopicus AM 3672	Antitumor
Maduropeptin	Actinomadura madurae ATCC 39144	Antibiotic; Antitumor
Medermycin	Streptomyces sp. AM-7161	Antibacterial; Antitumor
Myxalamid	Stigmatella aurantiaca Sga15	Antifungal; Antibacterial
Naphthocyclinone	Streptomyces arenae DSM 40737	Antibacterial
Neocarzinostatin	Streptomyces carzinostaticus ATCC 15944	Antibiotic; Antitumor
Niddamycin	Streptomyces caelestis NRRL 2821	Antibacterial
Phoslactomycin	Streptomyces sp. HK803	Antifungal; Antitumor
R1128	Streptomyces sp. R1128	Estrogen receptor antagonist
Streptolydigin	Streptomyces lydicus NRRL 2433 (=NBRC 13058)	Antibacterial
9
Borrelidin	Streptomyces parvulus Tu4055	Angiogenesis Inhibition; Antibacterial; Antiviral; Antiproliferative; Antiprotozoal
Oxytetracycline	Streptomyces rimosus ATCC 10970 (=NBRC 12907)	Antibacterial
Piericidin	Streptomyces piomogenus var. Hangzhouwanensis	Antibacterial; Antifungal; Antitumor
Soraphen	Sorangium cellulosum So ce26	Antifungal
Vicenistatin	Streptomyces halstedii HC34	Antitumor
10
Aclacinomycin A	Streptomyces galilaeus ATCC 31615	Antitumor; Toxic
Aranciamycin	Streptomyces echinatus Tu303	Antibacterial; Collagenase inhibitor
Chartreusin	Streptomyces chartreusis HKI-249	Antibacterial; Antitumor
Chromomycin	Streptomyces griseus ATCC 13273 (=NBRC 3746)	Antibacterial; Antitumor; Antiviral
Cosmomycin	Streptomyces olindensis DAUFPE 5622	Antitumor
Daunorubicin	Streptomyces sp. C5	Antitumor
Doxorubicin	Streptomyces peucetius ATCC 29050 (=NBRC 100596)	Antitumor
Elloramycin	Streptomyces olivaceus Tu2353	Antibacterial; Antitumor
Epothilone	Sorangium cellulosum So ce90	Antitumor
Gilvocarcin	Streptomyces griseoflavus Go 3592	Antibacterial; Antitumor; Antiviral
Indanomycin	Streptomyces antibioticus NRRL 8167	Antibacterial; Antiprotozoal; Insecticidal; Ionophore
Jadomycin B	Streptomyces venezuelae ISP5230 (=NBRC 13096)	Antibacterial
Landomycin	Streptomyces cyanogenus S136	Antitumor
Mithramycin	Streptomyces argillaceus ATCC 12956	Antibacterial; Antitumor
Nogalamycin	Streptomyces nogalater ATCC 27451 (=NBRC 13445)	Antibacterial; Antitumor; Toxic
Oviedomycin	Streptomyces antibioticus ATCC 11891	Antitumor
Oxazolomycin	Streptomyces albus JA3453	Antibacterial; Antitumor; Antivirus; Ionophore
Polyketomycin	Streptomyces diastatochromogenes Tu6028	Antibacterial; Antitumor
Resistomycin	Streptomyces resistomycificus HKI-237	Antibacterial; Antiviral
Sch 47554	Streptomyces sp. SCC-2136	Antifungal
Steffimycin	Streptomyces steffisburgensis NRRL 3193 (=NBRC 13446)	Antitumor
Tautomycetin	Streptomyces sp. CK4412	Antifungal; Antitumor; Immunosuppressive
Urdamycin	Streptomyces fradiae Tu2717	Antibacterial; Antitumor
11
Ascomycin	Streptomyces hygroscopicus subsp. ascomyceticus ATCC 14891 (=NBRC 13981)	Immunosuppressive; Antifungal
Pladienolide	Streptomyces platensis Mer-11107	Antitumor
Rifamycin	Amycolatopsis mediterranei S699	Antibacterial
Spinosyn	Saccharopolyspora spinosa NRRL 18538	Insecticidal
Stigmatellin	Stigmatella aurantiaca Sga15	Antifungal
12
Benastatin	Streptomyces sp. A2991200	Antibacterial; Apoptosis inducer; glutathione-S-transferase(GST) inhibitor
Chlorothricin	Streptomyces antibioticus DSM 40725	Antibacterial
Hedamycin	Streptomyces griseoruber ATCC 15422	Antitumor
Lasalocid	Streptomyces lasaliensis ATCC 35851	Antibacterial; Ionophore
Lasalocid	Streptomyces lasaliensis ATCC 31180	Antibacterial; Ionophore
13
Avermectin	Streptomyces avermitilis ATCC 31267 (=NBRC 14893)	Anthelmintic
FD-891	Streptomyces graminofaciens A-8890	Antitumor; Toxic
Fredericamycin	Streptomyces griseus ATCC 49344	Antibacterial; Antifungal; Antitumor
Griseorhodin A	Streptomyces sp. JP95	Antibacterial; human telomerase inhibitor
Meilingmycin	Streptomyces nanchangensis NS3226	Anthelmintic
Monensin	Streptomyces cinnamonensis ATCC 15413	Antibacterial; Ionophore; Antiprotozoal
Pimaricin	Streptomyces natalensis ATCC 27448 (=NBRC 13367)	Antifungal
Reveromycin	Streptomyces sp. SN-593	Antifungal; Antiosteoclastic
Tautomycin	Streptomyces spiroverticillatus	Antibacterial; Antifungal; Antitumor
Tetronomycin	Streptomyces sp. NRRL 11266	Antibacterial; Ionophore
14
Concanamycin A	Streptomyces neyagawaensis ATCC 27449 (=NBRC 13477)	Antifungal; Antiprotozoal; Antitumor; Antiviral
Rimocidin	Streptomyces diastaticus 108	Antifungal
15
Kirromycin	Streptomyces collinus Tu365	Antibacterial
Meridamycin	Streptomyces violaceusniger DSM 4137	Neuroprotective; Non-immunosuppressive
Nanchangmycin	Streptomyces nanchangensis NS3226	Antibacterial; Insecticidal; Ionophore
Nigericin	Streptomyces violaceusniger DSM 4137	Antibacterial; Ionophore
Rapamycin	Streptomyces rapamycinicus NRRL 5491	Immunosuppressive; Antitumor; Neuroprotective; Antiaging
Salinomycin	Streptomyces albus subsp. albus DSM 41398	Antibacterial; Antiprotozoal; Antitumor; Ionophore
Salinomycin	Streptomyces albus XM211	Antibacterial; Antiprotozoal; Antitumor; Ionophore
17
Oligomycin	Streptomyces avermitilis ATCC 31267 (=NBRC 14893)	Antifungal; Toxic; Antitumor
18
Lydicamycin	Streptomyces sp. TP-A0598 (=NBRC 110027)	Antibacterial
Mycolactone	Mycobacterium ulcerans Agy99	Toxic; Immunosuppressive
19
Amphotericin B	Streptomyces nodosus ATCC 14899 (=NBRC 12895)	Antifungal
Halstoctacosanolide	Streptomyces halstedii HC34	Antibacterial
Nystatin	Streptomyces noursei ATCC 11455 (=NBRC 15452)	Antifungal
22
FR-008	Streptomyces sp. FR-008	Antifungal
other
Griseusin	Streptomyces griseus K-63	Antibacterial

Compound name	organism	activity
L-daunosamine
Daunorubicin	Streptomyces sp. C5	Antitumor
Doxorubicin	Streptomyces peucetius ATCC 29050 (=NBRC 100596)	Antitumor
desosamine
Pikromycin	Streptomyces venezuelae ATCC 15439	Antibacterial
L-2-deoxyfucose
Aclacinomycin A	Streptomyces galilaeus ATCC 31615	Antitumor; Toxic
Cosmomycin	Streptomyces olindensis DAUFPE 5622	Antitumor
forosamine
Spinosyn	Saccharopolyspora spinosa NRRL 18538	Insecticidal
mycaminose
Niddamycin	Streptomyces caelestis NRRL 2821	Antibacterial
mycarose
Niddamycin	Streptomyces caelestis NRRL 2821	Antibacterial
mycosamine
Amphotericin B	Streptomyces nodosus ATCC 14899 (=NBRC 12895)	Antifungal
FR-008	Streptomyces sp. FR-008	Antifungal
Nystatin	Streptomyces noursei ATCC 11455 (=NBRC 15452)	Antifungal
Pimaricin	Streptomyces natalensis ATCC 27448 (=NBRC 13367)	Antifungal
Rimocidin	Streptomyces diastaticus 108	Antifungal
D-olivose
Chlorothricin	Streptomyces antibioticus DSM 40725	Antibacterial
Chromomycin	Streptomyces griseus ATCC 13273 (=NBRC 3746)	Antibacterial; Antitumor; Antiviral
Granaticin	Streptomyces violaceoruber Tu22	Antibacterial
Landomycin	Streptomyces cyanogenus S136	Antitumor
Mithramycin	Streptomyces argillaceus ATCC 12956	Antibacterial; Antitumor
Urdamycin	Streptomyces fradiae Tu2717	Antibacterial; Antitumor
2-O-methyl-L-rhamnose
Aranciamycin	Streptomyces echinatus Tu303	Antibacterial; Collagenase inhibitor
Steffimycin	Streptomyces steffisburgensis NRRL 3193 (=NBRC 13446)	Antitumor
L-rhodinose
Cosmomycin	Streptomyces olindensis DAUFPE 5622	Antitumor
Landomycin	Streptomyces cyanogenus S136	Antitumor
Streptolydigin	Streptomyces lydicus NRRL 2433 (=NBRC 13058)	Antibacterial
Urdamycin	Streptomyces fradiae Tu2717	Antibacterial; Antitumor
L-rhodosamine
Aclacinomycin A	Streptomyces galilaeus ATCC 31615	Antitumor; Toxic
Cosmomycin	Streptomyces olindensis DAUFPE 5622	Antitumor
other
A40926	Nonomuraea sp. ATCC 39727	Antibacterial
Aclacinomycin A	Streptomyces galilaeus ATCC 31615	Antitumor; Toxic
Alpha-lipomycin	Streptomyces aureofaciens Tu117	Antibacterial
Avermectin	Streptomyces avermitilis ATCC 31267 (=NBRC 14893)	Anthelmintic
Avilamycin	Streptomyces viridochromogenes Tu57	Antibacterial
Balhimycin	Amycolatopsis balhimycina DSM 5908	Antibacterial
C-1027	Streptomyces globisporus C-1027	Antibiotic; Antitumor
Calicheamicin	Micromonospora echinospora NRRL 15839	Antibiotic; Antitumor
Chalcomycin	Streptomyces bikiniensis NRRL 2737	Antibacterial
Chartreusin	Streptomyces chartreusis HKI-249	Antibacterial; Antitumor
Chloroeremomycin	Amycolatopsis orientalis A82846UV37B	Antibacterial
Chromomycin	Streptomyces griseus ATCC 13273 (=NBRC 3746)	Antibacterial; Antitumor; Antiviral
Concanamycin A	Streptomyces neyagawaensis ATCC 27449 (=NBRC 13477)	Antifungal; Antiprotozoal; Antitumor; Antiviral
Elloramycin	Streptomyces olivaceus Tu2353	Antibacterial; Antitumor
Gilvocarcin	Streptomyces griseoflavus Go 3592	Antibacterial; Antitumor; Antiviral
Hedamycin	Streptomyces griseoruber ATCC 15422	Antitumor
Jadomycin B	Streptomyces venezuelae ISP5230 (=NBRC 13096)	Antibacterial
Maduropeptin	Actinomadura madurae ATCC 39144	Antibiotic; Antitumor
Medermycin	Streptomyces sp. AM-7161	Antibacterial; Antitumor
Megalomicin	Micromonospora megalomicea subsp. nigra NRRL 3275 (=NBRC 14744)	Antibacterial; Antiparasitic; Antiviral
Mithramycin	Streptomyces argillaceus ATCC 12956	Antibacterial; Antitumor
Nanchangmycin	Streptomyces nanchangensis NS3226	Antibacterial; Insecticidal; Ionophore
Neocarzinostatin	Streptomyces carzinostaticus ATCC 15944	Antibiotic; Antitumor
Nogalamycin	Streptomyces nogalater ATCC 27451 (=NBRC 13445)	Antibacterial; Antitumor; Toxic
Polyketomycin	Streptomyces diastatochromogenes Tu6028	Antibacterial; Antitumor
Rubradirin	Streptomyces achromogenes var. rubradiris NRRL 3061 (=NBRC 14000)	Antibacterial
Sch 47554	Streptomyces sp. SCC-2136	Antifungal
Spinosyn	Saccharopolyspora spinosa NRRL 18538	Insecticidal
Teicoplanin	Actinoplanes teichomyceticus DSM 43866 (=NBRC 13999)	Antibacterial
Teicoplanin	Actinoplanes teichomyceticus ATCC 31121 (=NBRC 13999)	Antibacterial
Vancomycin	Amycolatopsis orientalis ATCC 19795 (=NBRC 12806)	Antibacterial
Vicenistatin	Streptomyces halstedii HC34	Antitumor
none
A47934	Streptomyces toyocaensis NRRL 15009	Antibacterial
Actinorhodin	Streptomyces coelicolor A3(2) (=NBRC 15146)	Antibacterial; Organocatalysis
Alnumycin	Streptomyces sp. CM020	Antitumor; Gyrase inhibitory; Topoisomerase inhibitory
Ansamitocin	Actinosynnema pretiosum subsp. auranticum ATCC 31565	Antifungal; Antitumor
Ascomycin	Streptomyces hygroscopicus subsp. ascomyceticus ATCC 14891 (=NBRC 13981)	Immunosuppressive; Antifungal
Aureothin	Streptomyces thioluteus HKI-227	Antitumor; Antifungal; Insecticidal
Azinomycin B	Streptomyces sahachiroi NRRL 2485 (=NBRC 13928)	Antitumor
Benastatin	Streptomyces sp. A2991200	Antibacterial; Apoptosis inducer; glutathione-S-transferase(GST) inhibitor
Borrelidin	Streptomyces parvulus Tu4055	Angiogenesis Inhibition; Antibacterial; Antiviral; Antiproliferative; Antiprotozoal
Cryptophycin 1	Nostoc sp. ATCC 53789	Toxic
Dynemicin	Micromonospora chersina ATCC 53710 (=NBRC 15963)	Antibiotic; Antitumor
Enterocin	Streptomyces maritimus	Antibacterial
Epothilone	Sorangium cellulosum So ce90	Antitumor
FD-891	Streptomyces graminofaciens A-8890	Antitumor; Toxic
Fredericamycin	Streptomyces griseus ATCC 49344	Antibacterial; Antifungal; Antitumor
Frenolicin	Streptomyces roseofulvus AK24158	Antibacterial; Antiprotozoal
Geldanamycin	Streptomyces hygroscopicus 17997	Antitumor; Antivirus
Geldanamycin	Streptomyces geldanamycininus NRRL 3602 (=NBRC 14620)	Antitumor; Antivirus
Griseorhodin A	Streptomyces sp. JP95	Antibacterial; human telomerase inhibitor
Griseusin	Streptomyces griseus K-63	Antibacterial
Halstoctacosanolide	Streptomyces halstedii HC34	Antibacterial
Hectochlorin	Lyngbya majuscula JHB	Antifungal; Antitumor; Toxic
Herbimycin A	Streptomyces hygroscopicus AM 3672	Antitumor
Indanomycin	Streptomyces antibioticus NRRL 8167	Antibacterial; Antiprotozoal; Insecticidal; Ionophore
Kirromycin	Streptomyces collinus Tu365	Antibacterial
Lasalocid	Streptomyces lasaliensis ATCC 35851	Antibacterial; Ionophore
Lasalocid	Streptomyces lasaliensis ATCC 31180	Antibacterial; Ionophore
Lydicamycin	Streptomyces sp. TP-A0598 (=NBRC 110027)	Antibacterial
Meilingmycin	Streptomyces nanchangensis NS3226	Anthelmintic
Meridamycin	Streptomyces violaceusniger DSM 4137	Neuroprotective; Non-immunosuppressive
Monensin	Streptomyces cinnamonensis ATCC 15413	Antibacterial; Ionophore; Antiprotozoal
Mycolactone	Mycobacterium ulcerans Agy99	Toxic; Immunosuppressive
Myxalamid	Stigmatella aurantiaca Sga15	Antifungal; Antibacterial
Myxothiazol	Stigmatella aurantiaca DW4/3-1	Antifungal
Naphthocyclinone	Streptomyces arenae DSM 40737	Antibacterial
Nigericin	Streptomyces violaceusniger DSM 4137	Antibacterial; Ionophore
Oligomycin	Streptomyces avermitilis ATCC 31267 (=NBRC 14893)	Antifungal; Toxic; Antitumor
Oviedomycin	Streptomyces antibioticus ATCC 11891	Antitumor
Oxazolomycin	Streptomyces albus JA3453	Antibacterial; Antitumor; Antivirus; Ionophore
Oxytetracycline	Streptomyces rimosus ATCC 10970 (=NBRC 12907)	Antibacterial
Pactamycin	Streptomyces pactum ATCC 27456 (=NBRC 13433)	Antibacterial; Antiprotozoal; Antitumor; Antiviral; Toxic
Phoslactomycin	Streptomyces sp. HK803	Antifungal; Antitumor
Piericidin	Streptomyces piomogenus var. Hangzhouwanensis	Antibacterial; Antifungal; Antitumor
Pladienolide	Streptomyces platensis Mer-11107	Antitumor
Pyoluteorin	Pseudomonas fluorescens Pf-5	Antibacterial; Antifungal
Pyrrolomycin	Actinosporangium vitaminophilum ATCC 31673 (=NBRC 14294)	Antibacterial [A, B, C, D, E]; Antifungal [A, B, D]; Immunopotentiator [B]; Toxic [C, D]
R1128	Streptomyces sp. R1128	Estrogen receptor antagonist
Rapamycin	Streptomyces rapamycinicus NRRL 5491	Immunosuppressive; Antitumor; Neuroprotective; Antiaging
Resistomycin	Streptomyces resistomycificus HKI-237	Antibacterial; Antiviral
Reveromycin	Streptomyces sp. SN-593	Antifungal; Antiosteoclastic
Rifamycin	Amycolatopsis mediterranei S699	Antibacterial
Salinomycin	Streptomyces albus subsp. albus DSM 41398	Antibacterial; Antiprotozoal; Antitumor; Ionophore
Salinomycin	Streptomyces albus XM211	Antibacterial; Antiprotozoal; Antitumor; Ionophore
Soraphen	Sorangium cellulosum So ce26	Antifungal
Stigmatellin	Stigmatella aurantiaca Sga15	Antifungal
Tautomycetin	Streptomyces sp. CK4412	Antifungal; Antitumor; Immunosuppressive
Tautomycin	Streptomyces spiroverticillatus	Antibacterial; Antifungal; Antitumor
Tetronomycin	Streptomyces sp. NRRL 11266	Antibacterial; Ionophore
Virginiamycin	Streptomyces virginiae MAFF 10-06014	Antibacterial

Compound name	organism	activity
Angucycline
Gilvocarcin	Streptomyces griseoflavus Go 3592	Antibacterial; Antitumor; Antiviral
Jadomycin B	Streptomyces venezuelae ISP5230 (=NBRC 13096)	Antibacterial
Landomycin	Streptomyces cyanogenus S136	Antitumor
Oviedomycin	Streptomyces antibioticus ATCC 11891	Antitumor
Sch 47554	Streptomyces sp. SCC-2136	Antifungal
Urdamycin	Streptomyces fradiae Tu2717	Antibacterial; Antitumor
Ansamycin
Ansamitocin	Actinosynnema pretiosum subsp. auranticum ATCC 31565	Antifungal; Antitumor
Geldanamycin	Streptomyces hygroscopicus 17997	Antitumor; Antivirus
Geldanamycin	Streptomyces geldanamycininus NRRL 3602 (=NBRC 14620)	Antitumor; Antivirus
Herbimycin A	Streptomyces hygroscopicus AM 3672	Antitumor
Rifamycin	Amycolatopsis mediterranei S699	Antibacterial
Rubradirin	Streptomyces achromogenes var. rubradiris NRRL 3061 (=NBRC 14000)	Antibacterial
Anthracycline
Aclacinomycin A	Streptomyces galilaeus ATCC 31615	Antitumor; Toxic
Aranciamycin	Streptomyces echinatus Tu303	Antibacterial; Collagenase inhibitor
Cosmomycin	Streptomyces olindensis DAUFPE 5622	Antitumor
Daunorubicin	Streptomyces sp. C5	Antitumor
Doxorubicin	Streptomyces peucetius ATCC 29050 (=NBRC 100596)	Antitumor
Nogalamycin	Streptomyces nogalater ATCC 27451 (=NBRC 13445)	Antibacterial; Antitumor; Toxic
Steffimycin	Streptomyces steffisburgensis NRRL 3193 (=NBRC 13446)	Antitumor
Aureolic acid
Chromomycin	Streptomyces griseus ATCC 13273 (=NBRC 3746)	Antibacterial; Antitumor; Antiviral
Mithramycin	Streptomyces argillaceus ATCC 12956	Antibacterial; Antitumor
Benzanthraquinone
Landomycin	Streptomyces cyanogenus S136	Antitumor
Oviedomycin	Streptomyces antibioticus ATCC 11891	Antitumor
Urdamycin	Streptomyces fradiae Tu2717	Antibacterial; Antitumor
Benzoisochromanequinone (BIQ)
Actinorhodin	Streptomyces coelicolor A3(2) (=NBRC 15146)	Antibacterial; Organocatalysis
Frenolicin	Streptomyces roseofulvus AK24158	Antibacterial; Antiprotozoal
Granaticin	Streptomyces violaceoruber Tu22	Antibacterial
Griseusin	Streptomyces griseus K-63	Antibacterial
Medermycin	Streptomyces sp. AM-7161	Antibacterial; Antitumor
Enediyne
C-1027	Streptomyces globisporus C-1027	Antibiotic; Antitumor
Calicheamicin	Micromonospora echinospora NRRL 15839	Antibiotic; Antitumor
Dynemicin	Micromonospora chersina ATCC 53710 (=NBRC 15963)	Antibiotic; Antitumor
Maduropeptin	Actinomadura madurae ATCC 39144	Antibiotic; Antitumor
Neocarzinostatin	Streptomyces carzinostaticus ATCC 15944	Antibiotic; Antitumor
Linear Polyene
Alpha-lipomycin	Streptomyces aureofaciens Tu117	Antibacterial
Myxalamid	Stigmatella aurantiaca Sga15	Antifungal; Antibacterial
Macrolide
Chalcomycin	Streptomyces bikiniensis NRRL 2737	Antibacterial
Megalomicin	Micromonospora megalomicea subsp. nigra NRRL 3275 (=NBRC 14744)	Antibacterial; Antiparasitic; Antiviral
Niddamycin	Streptomyces caelestis NRRL 2821	Antibacterial
Pikromycin	Streptomyces venezuelae ATCC 15439	Antibacterial
Spinosyn	Saccharopolyspora spinosa NRRL 18538	Insecticidal
Naphthoquinone
Alnumycin	Streptomyces sp. CM020	Antitumor; Gyrase inhibitory; Topoisomerase inhibitory
Naphthocyclinone	Streptomyces arenae DSM 40737	Antibacterial
Other Macrocyclic Lactone
Ascomycin	Streptomyces hygroscopicus subsp. ascomyceticus ATCC 14891 (=NBRC 13981)	Immunosuppressive; Antifungal
Avermectin	Streptomyces avermitilis ATCC 31267 (=NBRC 14893)	Anthelmintic
Borrelidin	Streptomyces parvulus Tu4055	Angiogenesis Inhibition; Antibacterial; Antiviral; Antiproliferative; Antiprotozoal
Concanamycin A	Streptomyces neyagawaensis ATCC 27449 (=NBRC 13477)	Antifungal; Antiprotozoal; Antitumor; Antiviral
Epothilone	Sorangium cellulosum So ce90	Antitumor
FD-891	Streptomyces graminofaciens A-8890	Antitumor; Toxic
Halstoctacosanolide	Streptomyces halstedii HC34	Antibacterial
Meilingmycin	Streptomyces nanchangensis NS3226	Anthelmintic
Meridamycin	Streptomyces violaceusniger DSM 4137	Neuroprotective; Non-immunosuppressive
Mycolactone	Mycobacterium ulcerans Agy99	Toxic; Immunosuppressive
Oligomycin	Streptomyces avermitilis ATCC 31267 (=NBRC 14893)	Antifungal; Toxic; Antitumor
Pladienolide	Streptomyces platensis Mer-11107	Antitumor
Rapamycin	Streptomyces rapamycinicus NRRL 5491	Immunosuppressive; Antitumor; Neuroprotective; Antiaging
Soraphen	Sorangium cellulosum So ce26	Antifungal
Peptide-Polyketide Hybrid
Alpha-lipomycin	Streptomyces aureofaciens Tu117	Antibacterial
Cryptophycin 1	Nostoc sp. ATCC 53789	Toxic
Kirromycin	Streptomyces collinus Tu365	Antibacterial
Myxalamid	Stigmatella aurantiaca Sga15	Antifungal; Antibacterial
Myxothiazol	Stigmatella aurantiaca DW4/3-1	Antifungal
Polyene Macrolide
Amphotericin B	Streptomyces nodosus ATCC 14899 (=NBRC 12895)	Antifungal
FR-008	Streptomyces sp. FR-008	Antifungal
Nystatin	Streptomyces noursei ATCC 11455 (=NBRC 15452)	Antifungal
Pimaricin	Streptomyces natalensis ATCC 27448 (=NBRC 13367)	Antifungal
Rimocidin	Streptomyces diastaticus 108	Antifungal
Polyether
Lasalocid	Streptomyces lasaliensis ATCC 35851	Antibacterial; Ionophore
Lasalocid	Streptomyces lasaliensis ATCC 31180	Antibacterial; Ionophore
Monensin	Streptomyces cinnamonensis ATCC 15413	Antibacterial; Ionophore; Antiprotozoal
Nanchangmycin	Streptomyces nanchangensis NS3226	Antibacterial; Insecticidal; Ionophore
Nigericin	Streptomyces violaceusniger DSM 4137	Antibacterial; Ionophore
Salinomycin	Streptomyces albus subsp. albus DSM 41398	Antibacterial; Antiprotozoal; Antitumor; Ionophore
Salinomycin	Streptomyces albus XM211	Antibacterial; Antiprotozoal; Antitumor; Ionophore
Tetronomycin	Streptomyces sp. NRRL 11266	Antibacterial; Ionophore
Pyrrole Antibiotic
Pyoluteorin	Pseudomonas fluorescens Pf-5	Antibacterial; Antifungal
Pyrrolomycin	Actinosporangium vitaminophilum ATCC 31673 (=NBRC 14294)	Antibacterial [A, B, C, D, E]; Antifungal [A, B, D]; Immunopotentiator [B]; Toxic [C, D]
Tetracycline
Oxytetracycline	Streptomyces rimosus ATCC 10970 (=NBRC 12907)	Antibacterial
Tetronic Acid Derivative
Chlorothricin	Streptomyces antibioticus DSM 40725	Antibacterial
Tautomycetin	Streptomyces sp. CK4412	Antifungal; Antitumor; Immunosuppressive
Tautomycin	Streptomyces spiroverticillatus	Antibacterial; Antifungal; Antitumor
Tetronomycin	Streptomyces sp. NRRL 11266	Antibacterial; Ionophore
other
A40926	Nonomuraea sp. ATCC 39727	Antibacterial
A47934	Streptomyces toyocaensis NRRL 15009	Antibacterial
Alnumycin	Streptomyces sp. CM020	Antitumor; Gyrase inhibitory; Topoisomerase inhibitory
Aureothin	Streptomyces thioluteus HKI-227	Antitumor; Antifungal; Insecticidal
Avilamycin	Streptomyces viridochromogenes Tu57	Antibacterial
Azinomycin B	Streptomyces sahachiroi NRRL 2485 (=NBRC 13928)	Antitumor
Benastatin	Streptomyces sp. A2991200	Antibacterial; Apoptosis inducer; glutathione-S-transferase(GST) inhibitor
Chartreusin	Streptomyces chartreusis HKI-249	Antibacterial; Antitumor
Elloramycin	Streptomyces olivaceus Tu2353	Antibacterial; Antitumor
Enterocin	Streptomyces maritimus	Antibacterial
Fredericamycin	Streptomyces griseus ATCC 49344	Antibacterial; Antifungal; Antitumor
Griseorhodin A	Streptomyces sp. JP95	Antibacterial; human telomerase inhibitor
Hectochlorin	Lyngbya majuscula JHB	Antifungal; Antitumor; Toxic
Hedamycin	Streptomyces griseoruber ATCC 15422	Antitumor
Lydicamycin	Streptomyces sp. TP-A0598 (=NBRC 110027)	Antibacterial
Naphthocyclinone	Streptomyces arenae DSM 40737	Antibacterial
Oxazolomycin	Streptomyces albus JA3453	Antibacterial; Antitumor; Antivirus; Ionophore
Pactamycin	Streptomyces pactum ATCC 27456 (=NBRC 13433)	Antibacterial; Antiprotozoal; Antitumor; Antiviral; Toxic
Phoslactomycin	Streptomyces sp. HK803	Antifungal; Antitumor
Piericidin	Streptomyces piomogenus var. Hangzhouwanensis	Antibacterial; Antifungal; Antitumor
Polyketomycin	Streptomyces diastatochromogenes Tu6028	Antibacterial; Antitumor
R1128	Streptomyces sp. R1128	Estrogen receptor antagonist
Resistomycin	Streptomyces resistomycificus HKI-237	Antibacterial; Antiviral
Reveromycin	Streptomyces sp. SN-593	Antifungal; Antiosteoclastic
Stigmatellin	Stigmatella aurantiaca Sga15	Antifungal
Streptolydigin	Streptomyces lydicus NRRL 2433 (=NBRC 13058)	Antibacterial
Teicoplanin	Actinoplanes teichomyceticus DSM 43866 (=NBRC 13999)	Antibacterial
Teicoplanin	Actinoplanes teichomyceticus ATCC 31121 (=NBRC 13999)	Antibacterial
Vicenistatin	Streptomyces halstedii HC34	Antitumor
Virginiamycin	Streptomyces virginiae MAFF 10-06014	Antibacterial
Glycopeptide(vancomycin-type)
Balhimycin	Amycolatopsis balhimycina DSM 5908	Antibacterial
Chloroeremomycin	Amycolatopsis orientalis A82846UV37B	Antibacterial
Vancomycin	Amycolatopsis orientalis ATCC 19795 (=NBRC 12806)	Antibacterial

About

Secondary metabolites produced by actinomycetes are important as lead-compounds and/or candidates for drug development. Polyketide synthases (PKSs) and non-ribosomal peptide synthetases (NRPSs) have been attracting much attention for their roles in constructing complex compounds. Secondary metabolite biosynthesis gene clusters are often used in biotechnological applications such as heterologous expression and combinatorial biosynthesis. Many scientific papers are published describing biosynthesis gene clusters every year, but information about a particular gene cluster is often dispersed in many references and is not described in a comprehensive manner.

We constructed a literature-based database about known PKS and NRPS gene clusters. The database consists of biosynthesis cluster information, search menu, retrieve information menu and KS/A domain sequence menu. Our database enables easy access to a comprehensive information related to biosynthesis clusters and browsing standardized up-to-date gene descriptions. Our database will thus serve as a useful reference for the analysis of secondary metabolites. biosynthetic gene clusters.

DoBISCUIT: a database of secondary metabolite biosynthetic gene clusters.
Ichikawa, N; Sasagawa, M; Yamamoto, M; Komaki, H; Yoshida, Y; Yamazaki, S and Fujita, N.
Nucleic Acids Research (2013) Database Issue Nucleic Acids Res. 2012 Nov 26.

What's new

2016-12-27: Release [3]

A40926; A47934; Lydicamycin
Update [42]

Actinorhodin; Alpha-lipomycin; Amphotericin B; Ansamitocin; Ascomycin; Aureothin; Azinomycin B; Balhimycin; Borrelidin; C-1027; Calicheamicin; Chloroeremomycin; Chlorothricin; Concanamycin A; Doxorubicin; Enterocin; Epothilone; FD-891; Jadomycin B; Medermycin; Mithramycin; Nogalamycin; Oligomycin; Oxytetracycline; Pactamycin; Piericidin; Pikromycin; Pimaricin; Pyoluteorin; Pyrrolomycin; Rapamycin; Reveromycin; Rifamycin; Rubradirin; Salinomycin; Spinosyn; Tautomycetin; Teicoplanin; Teicoplanin; Vancomycin; Vicenistatin; Virginiamycin