BLAST table : Mith_00040

DBUniProtKB
accessionDBalignmentEvalueScoreIdent.linkproductgeneorganismec
1
Q194R6_STRAA
(Q194R6)
[query] 1 - 460 (460)
[subject] 1 - 460 (460)
0.0 924   100% Methylenetetrahydrofolate reductase mtmA Streptomyces argillaceus 1.5.1.20
2
B0LJ02_9ACTO
(B0LJ02)
[query] 193 - 460 (460)
[subject] 18 - 285 (285)
1e-113 414   78% Methylenetetrahydrofolate reductase lct19 Streptomyces rishiriensis 1.5.1.20
3
D9XEY0_STRVR
(D9XEY0)
[query] 193 - 451 (460)
[subject] 18 - 276 (296)
1e-112 409   78% Methylenetetrahydrofolate reductase SSQG_00977 Streptomyces viridochromogenes DSM 40736 1.5.1.20
4
Q83X56_STRRO
(Q83X56)
[query] 185 - 460 (460)
[subject] 10 - 286 (286)
1e-110 404   74% Methylenetetrahydrofolate reductase lkmQ Streptomyces rochei
Streptomyces parvullus
1.5.1.20
5
Q8GGL6_STRAZ
(Q8GGL6)
[query] 164 - 456 (460)
[subject] 4 - 295 (303)
1e-110 402   71% Methylenetetrahydrofolate reductase Streptomyces atroolivaceus 1.5.1.20
6
A2AXF4_STRCM
(A2AXF4)
[query] 192 - 456 (460)
[subject] 28 - 292 (301)
1e-109 400   75% Methylenetetrahydrofolate reductase fnq15 Streptomyces cinnamonensis 1.5.1.20
7
B5HIQ2_STRPR
(B5HIQ2)
[query] 185 - 456 (460)
[subject] 21 - 292 (300)
1e-108 397   72% Methylenetetrahydrofolate reductase SSDG_05038 Streptomyces pristinaespiralis ATCC 25486 1.5.1.20
8
F2RH41_STRVP
(F2RH41)
[query] 172 - 457 (460)
[subject] 1 - 283 (286)
1e-108 397   71% Methylenetetrahydrofolate reductase SVEN_4083 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) 1.5.1.20
9
E1ARJ5_STRAU
(E1ARJ5)
[query] 174 - 456 (460)
[subject] 13 - 292 (301)
1e-108 396   72% Methylenetetrahydrofolate reductase sa57 Streptomyces aureofaciens 1.5.1.20
10
B0CN35_STRLA
(B0CN35)
[query] 185 - 451 (460)
[subject] 34 - 300 (313)
1e-107 392   73% Methylenetetrahydrofolate reductase sfmS2 Streptomyces lavendulae 1.5.1.20
11
Q938W5_STRFR
(Q938W5)
[query] 185 - 451 (460)
[subject] 23 - 288 (305)
1e-105 388   74% Methylenetetrahydrofolate reductase metF Streptomyces fradiae
Streptomyces roseoflavus
1.5.1.20
12
B4V6E8_9ACTO
(B4V6E8)
[query] 185 - 456 (460)
[subject] 22 - 292 (299)
1e-105 387   71% Methylenetetrahydrofolate reductase SSAG_03326 Streptomyces sp. Mg1 1.5.1.20
13
D1XIJ2_9ACTO
(D1XIJ2)
[query] 174 - 457 (460)
[subject] 18 - 298 (323)
1e-104 382   72% Methylenetetrahydrofolate reductase SACTEDRAFT_2502 Streptomyces sp. SA3_actE 1.5.1.20
14
D9WNY5_9ACTO
(D9WNY5)
[query] 185 - 451 (460)
[subject] 51 - 316 (326)
1e-103 380   73% Methylenetetrahydrofolate reductase SSOG_07672 Streptomyces himastatinicus ATCC 53653 1.5.1.20
15
E4N9T4_KITSK
(E4N9T4)
[query] 193 - 451 (460)
[subject] 41 - 299 (304)
7e-90 336   64% Methylenetetrahydrofolate reductase metF
KSE_21420
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1.5.1.20
16
D6AWV8_9ACTO
(D6AWV8)
[query] 193 - 451 (460)
[subject] 41 - 299 (306)
1e-89 335   64% Methylenetetrahydrofolate reductase SSHG_01162 Streptomyces albus J1074 1.5.1.20
17
E0KXA6_STRVO
(E0KXA6)
[query] 193 - 451 (460)
[subject] 41 - 299 (305)
8e-88 329   62% Methylenetetrahydrofolate reductase StrviDRAFT_7284 Streptomyces violaceusniger Tu 4113 1.5.1.20
18
D9W959_9ACTO
(D9W959)
[query] 195 - 451 (460)
[subject] 43 - 299 (305)
9e-88 328   62% Methylenetetrahydrofolate reductase SSOG_06555 Streptomyces himastatinicus ATCC 53653 1.5.1.20
19
F3NRH0_9ACTO
(F3NRH0)
[query] 184 - 451 (460)
[subject] 18 - 284 (292)
1e-87 328   60% Methylenetetrahydrofolate reductase SGM_5734 Streptomyces griseoaurantiacus M045 1.5.1.20
20
B5HCL5_STRPR
(B5HCL5)
[query] 184 - 451 (460)
[subject] 33 - 299 (305)
2e-87 328   60% Methylenetetrahydrofolate reductase SSDG_02831 Streptomyces pristinaespiralis ATCC 25486 1.5.1.20
21
D7CEV7_STRBB
(D7CEV7)
[query] 184 - 451 (460)
[subject] 18 - 284 (290)
6e-87 326   60% Methylenetetrahydrofolate reductase SBI_07859 Streptomyces bingchenggensis (strain BCW-1) 1.5.1.20
22
Q82AF8_STRAW
(Q82AF8)
[query] 161 - 451 (460)
[subject] 13 - 299 (307)
1e-86 325   57% Methylenetetrahydrofolate reductase metF
SAV6100
SAV_6100
Streptomyces avermitilis 1.5.1.20
23
Q9S2V3_STRCO
(Q9S2V3)
[query] 161 - 451 (460)
[subject] 13 - 299 (307)
2e-86 324   56% Methylenetetrahydrofolate reductase metF
SCO2103
Streptomyces coelicolor 1.5.1.20
24
C7QA95_CATAD
(C7QA95)
[query] 185 - 455 (460)
[subject] 34 - 303 (315)
2e-86 324   61% Methylenetetrahydrofolate reductase Caci_1572 Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897) 1.5.1.20
25
D6EJ01_STRLI
(D6EJ01)
[query] 161 - 451 (460)
[subject] 13 - 299 (307)
3e-86 323   56% Methylenetetrahydrofolate reductase SSPG_05441 Streptomyces lividans TK24 1.5.1.20
26
METF_STRLI
(O54235)
[query] 161 - 451 (460)
[subject] 13 - 299 (307)
3e-86 323   56% 5,10-methylenetetrahydrofolate reductase metF Streptomyces lividans 1.5.1.20
27
D9X286_STRVR
(D9X286)
[query] 193 - 451 (460)
[subject] 41 - 299 (307)
3e-86 323   61% Methylenetetrahydrofolate reductase SSQG_02046 Streptomyces viridochromogenes DSM 40736 1.5.1.20
28
E2PZT8_STRCL
(E2PZT8)
[query] 184 - 451 (460)
[subject] 33 - 299 (305)
4e-86 323   59% Methylenetetrahydrofolate reductase SCLAV_1318 Streptomyces clavuligerus ATCC 27064 1.5.1.20
29
D9XNZ8_9ACTO
(D9XNZ8)
[query] 161 - 451 (460)
[subject] 13 - 299 (307)
5e-86 323   56% Methylenetetrahydrofolate reductase SSRG_04619 Streptomyces griseoflavus Tu4000 1.5.1.20
30
D9VS35_9ACTO
(D9VS35)
[query] 184 - 451 (460)
[subject] 32 - 298 (304)
5e-86 323   59% Methylenetetrahydrofolate reductase SSNG_01936 Streptomyces sp. C 1.5.1.20
31
D6ARH7_STRFL
(D6ARH7)
[query] 184 - 451 (460)
[subject] 33 - 299 (305)
7e-86 322   57% Methylenetetrahydrofolate reductase SSGG_01245 Streptomyces roseosporus NRRL 15998 1.5.1.20
32
B5GMA9_STRCL
(B5GMA9)
[query] 195 - 451 (460)
[subject] 43 - 299 (303)
9e-86 322   61% Methylenetetrahydrofolate reductase SCLAV_p0932
SSCG_00483
Streptomyces clavuligerus ATCC 27064 1.5.1.20
33
F8K0T1_STRCT
(F8K0T1)
[query] 183 - 455 (460)
[subject] 32 - 303 (305)
1e-85 321   60% 5,10-methylenetetrahydrofolate reductase metF
SCAT_1225
Streptomyces cattleya 1.5.1.20
34
F2RI66_STRVP
(F2RI66)
[query] 195 - 451 (460)
[subject] 43 - 299 (305)
2e-85 321   60% Methylenetetrahydrofolate reductase SVEN_1762 Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) 1.5.1.20
35
B1VZV3_STRGG
(B1VZV3)
[query] 184 - 451 (460)
[subject] 33 - 299 (305)
3e-85 320   57% Methylenetetrahydrofolate reductase SGR_5399 Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) 1.5.1.20
36
D1XGH8_9ACTO
(D1XGH8)
[query] 184 - 451 (460)
[subject] 33 - 299 (305)
3e-85 320   58% Methylenetetrahydrofolate reductase SACTEDRAFT_1788 Streptomyces sp. SA3_actE 1.5.1.20
37
C9YTY9_STRSW
(C9YTY9)
[query] 184 - 451 (460)
[subject] 18 - 284 (292)
4e-85 320   59% Methylenetetrahydrofolate reductase metF
SCAB_67791
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1.5.1.20
38
E8VZC5_STRFA
(E8VZC5)
[query] 184 - 451 (460)
[subject] 33 - 299 (305)
4e-85 320   57% Methylenetetrahydrofolate reductase Sfla_4714 Streptomyces flavogriseus (strain ATCC 33331 / DSM 40990 / IAF-45CD) 1.5.1.20
39
D6KB79_9ACTO
(D6KB79)
[query] 184 - 451 (460)
[subject] 33 - 299 (307)
9e-85 318   58% Methylenetetrahydrofolate reductase SSTG_00868 Streptomyces sp. e14 1.5.1.20
40
B4V3E7_9ACTO
(B4V3E7)
[query] 184 - 451 (460)
[subject] 32 - 298 (304)
2e-84 317   58% Methylenetetrahydrofolate reductase SSAG_02275 Streptomyces sp. Mg1 1.5.1.20
41
D6XAA3_9ACTO
(D6XAA3)
[query] 193 - 451 (460)
[subject] 41 - 299 (307)
3e-84 317   60% Methylenetetrahydrofolate reductase SSEG_10804 Streptomyces sviceus ATCC 29083 1.5.1.20
42
D6M2D1_9ACTO
(D6M2D1)
[query] 193 - 451 (460)
[subject] 41 - 299 (306)
7e-84 316   59% Methylenetetrahydrofolate reductase SSBG_06219 Streptomyces sp. SPB74 1.5.1.20
43
F3ZJ61_9ACTO
(F3ZJ61)
[query] 193 - 451 (460)
[subject] 41 - 299 (306)
9e-83 312   59% Methylenetetrahydrofolate reductase STTU_5272 Streptomyces sp. Tu6071 1.5.1.20
44
A4X9V3_SALTO
(A4X9V3)
[query] 174 - 454 (460)
[subject] 25 - 302 (305)
3e-82 310   57% Methylenetetrahydrofolate reductase Strop_3250 Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) 1.5.1.20
45
D1A8T0_THECD
(D1A8T0)
[query] 193 - 453 (460)
[subject] 34 - 294 (308)
5e-82 309   59% Methylenetetrahydrofolate reductase Tcur_3026 Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081) 1.5.1.20
46
E8S5S4_MICSL
(E8S5S4)
[query] 174 - 454 (460)
[subject] 25 - 302 (305)
1e-81 308   57% Methylenetetrahydrofolate reductase ML5_3798 Micromonospora sp. (strain L5) 1.5.1.20
47
D9T6B3_MICAI
(D9T6B3)
[query] 174 - 454 (460)
[subject] 25 - 302 (305)
1e-81 308   57% Methylenetetrahydrofolate reductase Micau_4505 Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / JCM 10878 / NBRC 16125 / INA 9442) 1.5.1.20
48
D3Q9W8_STANL
(D3Q9W8)
[query] 164 - 452 (460)
[subject] 8 - 291 (298)
2e-81 307   54% Methylenetetrahydrofolate reductase Snas_5027 Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21) 1.5.1.20
49
A8LY71_SALAI
(A8LY71)
[query] 174 - 452 (460)
[subject] 25 - 300 (305)
7e-81 306   57% Methylenetetrahydrofolate reductase Sare_3477 Salinispora arenicola (strain CNS-205) 1.5.1.20
50
Q47R29_THEFY
(Q47R29)
[query] 182 - 451 (460)
[subject] 34 - 299 (312)
3e-79 300   57% Methylenetetrahydrofolate reductase Tfu_1050 Thermobifida fusca (strain YX) 1.5.1.20
51
C4RLK6_9ACTO
(C4RLK6)
[query] 174 - 454 (460)
[subject] 25 - 302 (305)
6e-79 299   56% Methylenetetrahydrofolate reductase MCAG_01242 Micromonospora sp. ATCC 39149 1.5.1.20
52
F4F1P1_VERMA
(F4F1P1)
[query] 174 - 456 (460)
[subject] 25 - 304 (305)
1e-78 298   55% Methylenetetrahydrofolate reductase VAB18032_26966 Verrucosispora maris (strain AB-18-032) 1.5.1.20
53
E3J0A3_FRASU
(E3J0A3)
[query] 185 - 456 (460)
[subject] 36 - 307 (311)
1e-78 298   57% Methylenetetrahydrofolate reductase FraEuI1c_2347 Frankia sp. (strain EuI1c) 1.5.1.20
54
D2SA96_GEOOG
(D2SA96)
[query] 159 - 451 (460)
[subject] 3 - 293 (300)
1e-78 298   54% Methylenetetrahydrofolate reductase Gobs_3307 Geodermatophilus obscurus (strain ATCC 25078 / DSM 43160 / JCM 3152 / G-20) 1.5.1.20
55
D6Y9E3_THEBD
(D6Y9E3)
[query] 193 - 452 (460)
[subject] 43 - 302 (308)
2e-78 298   57% Methylenetetrahydrofolate reductase Tbis_1345 Thermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / NBRC 14880 / R51) 1.5.1.20
56
D3CZU1_9ACTO
(D3CZU1)
[query] 185 - 451 (460)
[subject] 32 - 298 (300)
1e-77 295   57% Methylenetetrahydrofolate reductase FrEUN1fDRAFT_3062 Frankia sp. EUN1f 1.5.1.20
57
Q0RNS4_FRAAA
(Q0RNS4)
[query] 182 - 452 (460)
[subject] 19 - 285 (285)
2e-77 295   56% Methylenetetrahydrofolate reductase metF
FRAAL2163
Frankia alni (strain ACN14a) 1.5.1.20
58
A0LTK4_ACIC1
(A0LTK4)
[query] 185 - 454 (460)
[subject] 33 - 302 (331)
3e-77 294   56% Methylenetetrahydrofolate reductase Acel_0991 Acidothermus cellulolyticus (strain ATCC 43068 / 11B) 1.5.1.20
59
D2B6I2_STRRD
(D2B6I2)
[query] 193 - 451 (460)
[subject] 41 - 299 (310)
8e-77 292   56% Methylenetetrahydrofolate reductase Sros_2788 Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100) 1.5.1.20
60
F8AYD6_9ACTO
(F8AYD6)
[query] 182 - 452 (460)
[subject] 32 - 298 (299)
2e-76 291   56% 5,10-methylenetetrahydrofolate reductase FsymDg_3130 Frankia symbiont of Datisca glomerata 1.5.1.20
61
A8KZC8_FRASN
(A8KZC8)
[query] 193 - 451 (460)
[subject] 31 - 289 (291)
3e-76 290   58% Methylenetetrahydrofolate reductase Franean1_5126 Frankia sp. (strain EAN1pec) 1.5.1.20
62
Q2JD76_FRASC
(Q2JD76)
[query] 193 - 452 (460)
[subject] 39 - 298 (298)
9e-76 289   57% Methylenetetrahydrofolate reductase Francci3_1389 Frankia sp. (strain CcI3) 1.5.1.20
63
D7B1U2_NOCDD
(D7B1U2)
[query] 195 - 458 (460)
[subject] 40 - 303 (309)
9e-74 282   56% Methylenetetrahydrofolate reductase Ndas_3109 Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
1.5.1.20
64
D2Q0D1_KRIFD
(D2Q0D1)
[query] 182 - 452 (460)
[subject] 34 - 300 (304)
1e-73 282   52% Methylenetetrahydrofolate reductase Kfla_2858 Kribbella flavida (strain DSM 17836 / JCM 10339 / NBRC 14399) 1.5.1.20
65
F4CL56_9PSEU
(F4CL56)
[query] 185 - 447 (460)
[subject] 29 - 290 (300)
2e-73 281   57% Methylenetetrahydrofolate reductase Psed_2785 Pseudonocardia dioxanivorans CB1190 1.5.1.20
66
D9UHN3_9ACTO
(D9UHN3)
[query] 179 - 451 (460)
[subject] 35 - 309 (316)
8e-72 276   53% Methylenetetrahydrofolate reductase SSLG_01318 Streptomyces sp. SPB78 1.5.1.20
67
A4FGJ1_SACEN
(A4FGJ1)
[query] 193 - 454 (460)
[subject] 29 - 290 (297)
9e-72 275   54% Methylenetetrahydrofolate reductase metF
SACE_3895
Saccharopolyspora erythraea (strain NRRL 23338) 1.5.1.20
68
A3TKC9_9MICO
(A3TKC9)
[query] 185 - 454 (460)
[subject] 24 - 291 (295)
5e-71 273   52% Methylenetetrahydrofolate reductase JNB_01660 Janibacter sp. HTCC2649 1.5.1.20
69
C6W9J0_ACTMD
(C6W9J0)
[query] 168 - 451 (460)
[subject] 7 - 287 (296)
2e-70 271   52% Methylenetetrahydrofolate reductase Amir_1401 Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971) 1.5.1.20
70
D9UC91_9ACTO
(D9UC91)
[query] 1 - 174 (460)
[subject] 1 - 174 (407)
9e-70 269   79% S-adenosylmethionine synthase
MAT
Methionine adenosyltransferase
metK
SSLG_00718
Streptomyces sp. SPB78 2.5.1.6
71
F3Z8U1_9ACTO
(F3Z8U1)
[query] 1 - 174 (460)
[subject] 1 - 174 (407)
1e-69 268   79% S-adenosylmethionine synthase
MAT
Methionine adenosyltransferase
metK
STTU_5879
Streptomyces sp. Tu6071 2.5.1.6
72
A4FAF8_SACEN
(A4FAF8)
[query] 193 - 451 (460)
[subject] 29 - 287 (294)
3e-69 267   54% Methylenetetrahydrofolate reductase metF
SACE_1715
Saccharopolyspora erythraea (strain NRRL 23338) 1.5.1.20
73
C8XCS7_NAKMY
(C8XCS7)
[query] 194 - 447 (460)
[subject] 30 - 283 (295)
3e-69 267   54% Methylenetetrahydrofolate reductase Namu_3198 Nakamurella multipartita (strain ATCC 700099 / DSM 44233 / JCM 9543 / Y-104)
Microsphaera multipartita
1.5.1.20
74
D5USJ0_TSUPD
(D5USJ0)
[query] 163 - 452 (460)
[subject] 11 - 304 (313)
1e-68 265   52% Methylenetetrahydrofolate reductase Tpau_2661 Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / JCM 10117 / NBRC 16120 / NCTC 13040)
Corynebacterium paurometabolum
1.5.1.20
75
B5GBK0_9ACTO
(B5GBK0)
[query] 1 - 174 (460)
[subject] 1 - 174 (407)
1e-68 265   78% S-adenosylmethionine synthase
MAT
Methionine adenosyltransferase
metK
SSBG_01686
Streptomyces sp. SPB74 2.5.1.6
76
Q0SHQ4_RHOSR
(Q0SHQ4)
[query] 185 - 447 (460)
[subject] 42 - 311 (335)
4e-68 263   54% Methylenetetrahydrofolate reductase RHA1_ro01105 Rhodococcus sp. (strain RHA1) 1.5.1.20
77
C1AU72_RHOOB
(C1AU72)
[query] 185 - 447 (460)
[subject] 28 - 297 (321)
4e-68 263   54% Methylenetetrahydrofolate reductase metF
ROP_08330
Rhodococcus opacus (strain B4) 1.5.1.20
78
D9UBI9_STRPR
(D9UBI9)
[query] 1 - 174 (460)
[subject] 1 - 169 (402)
9e-68 262   77% S-adenosylmethionine synthase
MAT
Methionine adenosyltransferase
samS
metK
Streptomyces pristinaespiralis 2.5.1.6
79
B5HIQ5_STRPR
(B5HIQ5)
[query] 1 - 174 (460)
[subject] 1 - 169 (402)
9e-68 262   77% S-adenosylmethionine synthase 2
MAT 2
Methionine adenosyltransferase 2
metK2
SSDG_05041
Streptomyces pristinaespiralis ATCC 25486 2.5.1.6
80
B0CN38_STRLA
(B0CN38)
[query] 3 - 257 (460)
[subject] 2 - 226 (401)
2e-67 261   58% S-adenosylmethionine synthase
MAT
Methionine adenosyltransferase
sfmS5
metK
Streptomyces lavendulae 2.5.1.6
81
D8HUS5_AMYMU
(D8HUS5)
[query] 168 - 447 (460)
[subject] 7 - 283 (294)
2e-67 261   50% Methylenetetrahydrofolate reductase metF
AMED_2326
Amycolatopsis mediterranei (strain U-32) 1.5.1.20
82
A2AXF1_STRCM
(A2AXF1)
[query] 1 - 174 (460)
[subject] 1 - 174 (408)
2e-67 261   76% S-adenosylmethionine synthase
MAT
Methionine adenosyltransferase
fnq12
metK
Streptomyces cinnamonensis 2.5.1.6
83
D9W3B9_9ACTO
(D9W3B9)
[query] 1 - 174 (460)
[subject] 1 - 169 (402)
2e-67 261   78% S-adenosylmethionine synthase 2
MAT 2
Methionine adenosyltransferase 2
metK2
SSNG_05645
Streptomyces sp. C 2.5.1.6
84
E9T6J1_COREQ
(E9T6J1)
[query] 185 - 459 (460)
[subject] 45 - 326 (326)
3e-67 260   52% Methylenetetrahydrofolate reductase metF
HMPREF0724_14414
Rhodococcus equi ATCC 33707 1.5.1.20
85
E4WIQ7_RHOE1
(E4WIQ7)
[query] 185 - 459 (460)
[subject] 31 - 312 (312)
4e-67 260   52% Methylenetetrahydrofolate reductase REQ_27970 Rhodococcus equi (strain 103S)
Corynebacterium equi
1.5.1.20
86
B4V6F1_9ACTO
(B4V6F1)
[query] 1 - 253 (460)
[subject] 1 - 226 (402)
5e-67 259   58% S-adenosylmethionine synthase 2
MAT 2
Methionine adenosyltransferase 2
metK2
SSAG_03329
Streptomyces sp. Mg1 2.5.1.6
87
D9UVG6_9ACTO
(D9UVG6)
[query] 168 - 451 (460)
[subject] 7 - 287 (295)
8e-67 259   51% Methylenetetrahydrofolate reductase SSMG_01853 Streptomyces sp. AA4 1.5.1.20
88
E6SBW1_INTC7
(E6SBW1)
[query] 174 - 451 (460)
[subject] 28 - 302 (302)
8e-67 259   49% Methylenetetrahydrofolate reductase Intca_1959 Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KIP) 1.5.1.20
89
Q3HW35_STRAW
(Q3HW35)
[query] 1 - 174 (460)
[subject] 1 - 169 (402)
9e-67 259   78% S-adenosylmethionine synthase 2
MAT 2
Methionine adenosyltransferase 2
metK
metK2
Streptomyces avermitilis 2.5.1.6
90
METK_STRAW
(Q827Q0)
[query] 1 - 174 (460)
[subject] 1 - 169 (402)
9e-67 259   78% S-adenosylmethionine synthase
MAT
Methionine adenosyltransferase
metK
SAV_6874
Streptomyces avermitilis 2.5.1.6
91
B0LJ35_9ACTO
(B0LJ35)
[query] 1 - 174 (460)
[subject] 1 - 172 (405)
1e-66 258   78% S-adenosylmethionine synthase
MAT
Methionine adenosyltransferase
lct52
metK
Streptomyces rishiriensis 2.5.1.6
92
D9XEY3_STRVR
(D9XEY3)
[query] 1 - 174 (460)
[subject] 1 - 169 (403)
1e-66 258   78% S-adenosylmethionine synthase 1
MAT 1
Methionine adenosyltransferase 1
metK1
SSQG_00980
Streptomyces viridochromogenes DSM 40736 2.5.1.6
93
C1A0Z2_RHOE4
(C1A0Z2)
[query] 185 - 459 (460)
[subject] 42 - 323 (329)
1e-66 258   51% Methylenetetrahydrofolate reductase metF
RER_35690
Rhodococcus erythropolis (strain PR4 / NBRC 100887) 1.5.1.20
94
C3JJ66_RHOER
(C3JJ66)
[query] 185 - 459 (460)
[subject] 42 - 323 (329)
1e-66 258   51% Methylenetetrahydrofolate reductase metF
RHOER0001_6428
Rhodococcus erythropolis SK121 1.5.1.20
95
B5HZZ4_9ACTO
(B5HZZ4)
[query] 1 - 174 (460)
[subject] 1 - 169 (402)
2e-66 258   77% S-adenosylmethionine synthase
MAT
Methionine adenosyltransferase
metK
SSEG_04979
Streptomyces sviceus ATCC 29083 2.5.1.6
96
METK_STRST
(Q9X4Q2)
[query] 1 - 174 (460)
[subject] 1 - 169 (411)
3e-66 257   78% S-adenosylmethionine synthase
MAT
Methionine adenosyltransferase
metK Streptomyces spectabilis 2.5.1.6
97
D9VK40_9ACTO
(D9VK40)
[query] 1 - 174 (460)
[subject] 1 - 169 (402)
1e-65 255   76% S-adenosylmethionine synthase 1
MAT 1
Methionine adenosyltransferase 1
metK1
SSNG_01323
Streptomyces sp. C 2.5.1.6
98
E1ARJ8_STRAU
(E1ARJ8)
[query] 1 - 174 (460)
[subject] 1 - 169 (403)
2e-65 254   76% S-adenosylmethionine synthase
MAT
Methionine adenosyltransferase
metK
sa54
Streptomyces aureofaciens 2.5.1.6
99
B4V641_9ACTO
(B4V641)
[query] 1 - 174 (460)
[subject] 1 - 169 (402)
2e-65 254   75% S-adenosylmethionine synthase 1
MAT 1
Methionine adenosyltransferase 1
metK1
SSAG_03219
Streptomyces sp. Mg1 2.5.1.6
100
Q5YZ05_NOCFA
(Q5YZ05)
[query] 185 - 451 (460)
[subject] 37 - 310 (321)
3e-65 254   52% Methylenetetrahydrofolate reductase metF
NFA_17400
Nocardia farcinica 1.5.1.20
accessionDBalignmentEvalueScoreIdent.linkinformationpubmed
1
Q194R6_STRAA
(Q194R6)
[query] 1 - 460 (460)
[subject] 1 - 460 (460)
0.0 924   100%
Product
Methylenetetrahydrofolate reductase
Gene
mtmA
Organism
Streptomyces argillaceus
1uniprot[Pubmed] 8654997 [Medline] 96257259
Characterization of Streptomyces argillaceus genes encoding a polyketide synthase involved in the biosynthesis of the antitumor mithramycin.(Gene) [1996]
2uniprot[Pubmed] 8757400 [Medline] 96335144
An ABC transporter is essential for resistance to the antitumor agent mithramycin in the producer Streptomyces argillaceus.(Mol. Gen. Genet.) [1996]
3uniprot[Pubmed] 9150235 [Medline] 97294479
Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin.(J. Bacteriol.) [1997]
4uniprot[Pubmed] 9733697 [Medline] 98406047
Identification of two genes from Streptomyces argillaceus encoding glycosyltransferases involved in transfer of a disaccharide during biosynthesis of the antitumor drug mithramycin.(J. Bacteriol.) [1998]
5uniprot[Pubmed] 10102355 [Medline] 99200478
Analysis of two chromosomal regions adjacent to genes for a type II polyketide synthase involved in the biosynthesis of the antitumor polyketide mithramycin in Streptomyces argillaceus.(Mol. Gen. Genet.) [1999]
6uniprot[Pubmed] 9889148 [Medline] 99111236
Oxidative cleavage of premithramycin B is one of the last steps in the biosynthesis of the antitumor drug mithramycin.(Chem. Biol.) [1999]
7uniprot[Pubmed] 10660060 [Medline] 20123456
Characterization of two glycosyltransferases involved in early glycosylation steps during biosynthesis of the antitumor polyketide mithramycin by Streptomyces argillaceus.(Mol. Gen. Genet.) [2000]
8uniprot[Pubmed] 11254130 [Medline] 21148776
The mtmVUC genes of the mithramycin gene cluster in Streptomyces argillaceus are involved in the biosynthesis of the sugar moieties.(Mol. Gen. Genet.) [2001]
9uniprot[Pubmed] 12733914 [Medline] 22619809
Mithramycin SK, a novel antitumor drug with improved therapeutic index, mithramycin SA, and demycarosyl-mithramycin SK: three new products generated in the mithramycin producer Streptomyces argillaceus through combinatorial biosynthesis.(J. Am. Chem. Soc.) [2003]
10uniprot[Pubmed] 9917296 [Medline] 99115752
The structure of mithramycin reinvestigated.(J. Nat. Prod.) [1999]
11uniprot[Pubmed] 11853433 [Medline] 21843297
Ketopremithramycins and ketomithramycins, four new aureolic acid-type compounds obtained upon inactivation of two genes involved in the biosynthesis of the deoxysugar moieties of the antitumor drug mithramycin by Streptomyces argillaceus, reveal novel insights into post-PKS tailoring steps of the mithramycin biosynthetic pathway.(J. Am. Chem. Soc.) [2002]
12uniprot[Pubmed] 10652287 [Medline] 20119254
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.(J. Biol. Chem.) [2000]
13uniprot[Pubmed] 10779713 [Medline] 20243461
Insertional inactivation of mtrX and mtrY genes from the mithramycin gene cluster affects production and growth of the producer organism Streptomyces argillaceus.(FEMS Microbiol. Lett.) [2000]
14uniprot[Pubmed] 12022840 [Medline] 22017994
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.(J. Am. Chem. Soc.) [2002]
15uniprot[Pubmed] 12813091 [Medline] 22697398
Purification and characterization of a monooxygenase involved in the biosynthetic pathway of the antitumor drug mithramycin.(J. Bacteriol.) [2003]
16uniprot[Pubmed] 8807845 [Medline] 97113238
Deciphering the biosynthetic origin of the aglycone of the aureolic acid group of anti-tumor agents.(Chem. Biol.) [1996]
17uniprot[Pubmed] 14660589
MtmMII-mediated C-methylation during biosynthesis of the antitumor drug mithramycin is essential for biological activity and DNA-drug interaction.(J. Biol. Chem.) [2004]
18uniprot[Pubmed] 9375253 [Medline] 98042823
Folding of the polyketide chain is not dictated by minimal polyketide synthase in the biosynthesis of mithramycin and anthracycline.(Chem. Biol.) [1997]
19uniprot[Pubmed] 15712316
Elucidation of the glycosylation sequence of mithramycin biosynthesis: isolation of 3A-deolivosylpremithramycin B and its conversion to premithramycin B by glycosyltransferase MtmGII.(Chembiochem) [2005]
20uniprot[Pubmed] 10760873
The Novel Hybrid Antitumor Compound Premithramycinone H Provides Indirect Evidence for a Tricyclic Intermediate of the Biosynthesis of the Aureolic Acid Antibiotic Mithramycin.(Angew. Chem. Int. Ed.) [2000]
[pubmed all]
2
B0LJ02_9ACTO
(B0LJ02)
[query] 193 - 460 (460)
[subject] 18 - 285 (285)
1e-113 414   78%
Product
Methylenetetrahydrofolate reductase
Gene
lct19
Organism
Streptomyces rishiriensis
1uniprot[Pubmed] 18070976
Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]
4
Q83X56_STRRO
(Q83X56)
[query] 185 - 460 (460)
[subject] 10 - 286 (286)
1e-110 404   74%
Product
Methylenetetrahydrofolate reductase
Gene
lkmQ
Organism
Streptomyces rochei
Streptomyces parvullus
1uniprot[Pubmed] 12791134 [Medline] 22676866
The large linear plasmid pSLA2-L of Streptomyces rochei has an unusually condensed gene organization for secondary metabolism.(Mol. Microbiol.) [2003]
2uniprot[Pubmed] 10954087 [Medline] 20408175
Cloning and analysis of the replication origin and the telomeres of the large linear plasmid pSLA2-L in Streptomyces rochei.(Mol. Gen. Genet.) [2000]
3uniprot[Pubmed] 10767533 [Medline] 20231737
Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei.(Gene) [2000]
4uniprot[Pubmed] 9836424 [Medline] 99053144
Physical mapping of the linear plasmid pSLA2-L and localization of the eryAI and actI homologs.(Biosci. Biotechnol. Biochem.) [1998]
[pubmed all]
5
Q8GGL6_STRAZ
(Q8GGL6)
[query] 164 - 456 (460)
[subject] 4 - 295 (303)
1e-110 402   71%
Product
Methylenetetrahydrofolate reductase
Gene
 
Organism
Streptomyces atroolivaceus
1uniprot[Pubmed] 12446651 [Medline] 22336326
Identification and localization of the gene cluster encoding biosynthesis of the antitumor macrolactam leinamycin in Streptomyces atroolivaceus S-140.(J. Bacteriol.) [2002]
2uniprot[Pubmed] 12598647 [Medline] 22531819
Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis.(Proc. Natl. Acad. Sci. U.S.A.) [2003]
3uniprot[Pubmed] 15112993
Leinamycin biosynthesis revealing unprecedented architectural complexity for a hybrid polyketide synthase and nonribosomal peptide synthetase.(Chem. Biol.) [2004]
[pubmed all]
6
A2AXF4_STRCM
(A2AXF4)
[query] 192 - 456 (460)
[subject] 28 - 292 (301)
1e-109 400   75%
Product
Methylenetetrahydrofolate reductase
Gene
fnq15
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 17103476
A gene cluster for prenylated naphthoquinone and prenylated phenazine biosynthesis in Streptomyces cinnamonensis DSM 1042.(Chembiochem) [2006]
8
F2RH41_STRVP
(F2RH41)
[query] 172 - 457 (460)
[subject] 1 - 283 (286)
1e-108 397   71%
Product
Methylenetetrahydrofolate reductase
Gene
SVEN_4083
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
9
E1ARJ5_STRAU
(E1ARJ5)
[query] 174 - 456 (460)
[subject] 13 - 292 (301)
1e-108 396   72%
Product
Methylenetetrahydrofolate reductase
Gene
sa57
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
10
B0CN35_STRLA
(B0CN35)
[query] 185 - 451 (460)
[subject] 34 - 300 (313)
1e-107 392   73%
Product
Methylenetetrahydrofolate reductase
Gene
sfmS2
Organism
Streptomyces lavendulae
1uniprot[Pubmed] 17981978
Characterization of the saframycin A gene cluster from Streptomyces lavendulae NRRL 11002 revealing a nonribosomal peptide synthetase system for assembling the unusual tetrapeptidyl skeleton in an iterative manner.(J. Bacteriol.) [2008]
11
Q938W5_STRFR
(Q938W5)
[query] 185 - 451 (460)
[subject] 23 - 288 (305)
1e-105 388   74%
Product
Methylenetetrahydrofolate reductase
Gene
metF
Organism
Streptomyces fradiae
Streptomyces roseoflavus
1uniprot
Influence of ancillarygenes, encoding aspects of methionine metabolism, on tylosin biosynthesis in Streptomyces fradiae.(J. Antibiot.) [2001]
15
E4N9T4_KITSK
(E4N9T4)
[query] 193 - 451 (460)
[subject] 41 - 299 (304)
7e-90 336   64%
Product
Methylenetetrahydrofolate reductase
Gene
metF
KSE_21420
Organism
Kitasatospora setae (strain ATCC 33774 / DSM 43861 / JCM 3304 / KCC A-0304 / NBRC 14216 / KM-6054)
Streptomyces setae
1uniprot[Pubmed] 21059706
Genome sequence of Kitasatospora setae NBRC 14216T: an evolutionary snapshot of the family Streptomycetaceae.(DNA Res.) [2010]
19
F3NRH0_9ACTO
(F3NRH0)
[query] 184 - 451 (460)
[subject] 18 - 284 (292)
1e-87 328   60%
Product
Methylenetetrahydrofolate reductase
Gene
SGM_5734
Organism
Streptomyces griseoaurantiacus M045
1uniprot[Pubmed] 21551298
Draft Genome Sequence of the Marine Bacterium Streptomyces griseoaurantiacus M045, Which Produces Novel Manumycin-Type Antibiotics with a pABA Core Component.(J. Bacteriol.) [2011]
21
D7CEV7_STRBB
(D7CEV7)
[query] 184 - 451 (460)
[subject] 18 - 284 (290)
6e-87 326   60%
Product
Methylenetetrahydrofolate reductase
Gene
SBI_07859
Organism
Streptomyces bingchenggensis (strain BCW-1)
1uniprot[Pubmed] 20581206
Genome sequence of the milbemycin-producing bacterium Streptomyces bingchenggensis.(J. Bacteriol.) [2010]
22
Q82AF8_STRAW
(Q82AF8)
[query] 161 - 451 (460)
[subject] 13 - 299 (307)
1e-86 325   57%
Product
Methylenetetrahydrofolate reductase
Gene
metF
SAV6100
SAV_6100
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
23
Q9S2V3_STRCO
(Q9S2V3)
[query] 161 - 451 (460)
[subject] 13 - 299 (307)
2e-86 324   56%
Product
Methylenetetrahydrofolate reductase
Gene
metF
SCO2103
Organism
Streptomyces coelicolor
1uniprot[Pubmed] 12000953 [Medline] 21996410
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).(Nature) [2002]
24
C7QA95_CATAD
(C7QA95)
[query] 185 - 455 (460)
[subject] 34 - 303 (315)
2e-86 324   61%
Product
Methylenetetrahydrofolate reductase
Gene
Caci_1572
Organism
Catenulispora acidiphila (strain DSM 44928 / NRRL B-24433 / NBRC 102108 / JCM 14897)
1uniprot
Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).(Stand. Genomic Sci.) [2009]
26
METF_STRLI
(O54235)
[query] 161 - 451 (460)
[subject] 13 - 299 (307)
3e-86 323   56%
Product
5,10-methylenetetrahydrofolate reductase
Gene
metF
Organism
Streptomyces lividans
1uniprot[Pubmed] 9515933 [Medline] 98175688
The folate branch of the methionine biosynthesis pathway in Streptomyces lividans: disruption of the 5,10-methylenetetrahydrofolate reductase gene leads to methionine auxotrophy.(J. Bacteriol.) [1998]
28
E2PZT8_STRCL
(E2PZT8)
[query] 184 - 451 (460)
[subject] 33 - 299 (305)
4e-86 323   59%
Product
Methylenetetrahydrofolate reductase
Gene
SCLAV_1318
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot[Pubmed] 20624727
The sequence of a 1.8-mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
32
B5GMA9_STRCL
(B5GMA9)
[query] 195 - 451 (460)
[subject] 43 - 299 (303)
9e-86 322   61%
Product
Methylenetetrahydrofolate reductase
Gene
SCLAV_p0932
SSCG_00483
Organism
Streptomyces clavuligerus ATCC 27064
1uniprot
The sequence of a 1.8 Mb bacterial linear plasmid reveals a rich evolutionary reservoir of secondary metabolic pathways.(Genome Biol. Evol.) [2010]
34
F2RI66_STRVP
(F2RI66)
[query] 195 - 451 (460)
[subject] 43 - 299 (305)
2e-85 321   60%
Product
Methylenetetrahydrofolate reductase
Gene
SVEN_1762
Organism
Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745)
1uniprot[Pubmed] 21463507
Genome-wide analysis of the role of GlnR in Streptomyces venezuelae provides new insights into global nitrogen regulation in actinomycetes.(BMC Genomics) [2011]
35
B1VZV3_STRGG
(B1VZV3)
[query] 184 - 451 (460)
[subject] 33 - 299 (305)
3e-85 320   57%
Product
Methylenetetrahydrofolate reductase
Gene
SGR_5399
Organism
Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
1uniprot[Pubmed] 18375553
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.(J. Bacteriol.) [2008]
37
C9YTY9_STRSW
(C9YTY9)
[query] 184 - 451 (460)
[subject] 18 - 284 (292)
4e-85 320   59%
Product
Methylenetetrahydrofolate reductase
Gene
metF
SCAB_67791
Organism
Streptomyces scabies (strain 87.22)
Streptomyces scabiei
1uniprot[Pubmed] 20064060
Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.(Mol. Plant Microbe Interact.) [2010]
45
D1A8T0_THECD
(D1A8T0)
[query] 193 - 453 (460)
[subject] 34 - 294 (308)
5e-82 309   59%
Product
Methylenetetrahydrofolate reductase
Gene
Tcur_3026
Organism
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
1uniprot
Complete genome sequence of Thermomonospora curvata type strain (B9).(Stand. Genomic Sci.) [2011]
48
D3Q9W8_STANL
(D3Q9W8)
[query] 164 - 452 (460)
[subject] 8 - 291 (298)
2e-81 307   54%
Product
Methylenetetrahydrofolate reductase
Gene
Snas_5027
Organism
Stackebrandtia nassauensis (strain DSM 44728 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)
1uniprot
Complete genome sequence of Stackebrandtia nassauensis type strain (LLR-40K-21T).(Stand. Genomic Sci.) [2009]
50
Q47R29_THEFY
(Q47R29)
[query] 182 - 451 (460)
[subject] 34 - 299 (312)
3e-79 300   57%
Product
Methylenetetrahydrofolate reductase
Gene
Tfu_1050
Organism
Thermobifida fusca (strain YX)
1uniprot[Pubmed] 17209016
Genome sequence and analysis of the soil cellulolytic actinomycete Thermobifida fusca YX.(J. Bacteriol.) [2007]
52
F4F1P1_VERMA
(F4F1P1)
[query] 174 - 456 (460)
[subject] 25 - 304 (305)
1e-78 298   55%
Product
Methylenetetrahydrofolate reductase
Gene
VAB18032_26966
Organism
Verrucosispora maris (strain AB-18-032)
1uniprot[Pubmed] 21551311
Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.(J. Bacteriol.) [2011]
57
Q0RNS4_FRAAA
(Q0RNS4)
[query] 182 - 452 (460)
[subject] 19 - 285 (285)
2e-77 295   56%
Product
Methylenetetrahydrofolate reductase
Gene
metF
FRAAL2163
Organism
Frankia alni (strain ACN14a)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
59
D2B6I2_STRRD
(D2B6I2)
[query] 193 - 451 (460)
[subject] 41 - 299 (310)
8e-77 292   56%
Product
Methylenetetrahydrofolate reductase
Gene
Sros_2788
Organism
Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)
1uniprot
Complete genome sequence of Streptosporangium roseum type strain (NI 9100T).(Stand. Genomic Sci.) [2010]
61
A8KZC8_FRASN
(A8KZC8)
[query] 193 - 451 (460)
[subject] 31 - 289 (291)
3e-76 290   58%
Product
Methylenetetrahydrofolate reductase
Gene
Franean1_5126
Organism
Frankia sp. (strain EAN1pec)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
62
Q2JD76_FRASC
(Q2JD76)
[query] 193 - 452 (460)
[subject] 39 - 298 (298)
9e-76 289   57%
Product
Methylenetetrahydrofolate reductase
Gene
Francci3_1389
Organism
Frankia sp. (strain CcI3)
1uniprot[Pubmed] 17151343
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography.(Genome Res.) [2007]
63
D7B1U2_NOCDD
(D7B1U2)
[query] 195 - 458 (460)
[subject] 40 - 303 (309)
9e-74 282   56%
Product
Methylenetetrahydrofolate reductase
Gene
Ndas_3109
Organism
Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / IMRU 509 / JCM 7437 / NCTC 10488)
Actinomadura dassonvillei
1uniprot
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509T).(Stand. Genomic Sci.) [2010]
67
A4FGJ1_SACEN
(A4FGJ1)
[query] 193 - 454 (460)
[subject] 29 - 290 (297)
9e-72 275   54%
Product
Methylenetetrahydrofolate reductase
Gene
metF
SACE_3895
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
68
A3TKC9_9MICO
(A3TKC9)
[query] 185 - 454 (460)
[subject] 24 - 291 (295)
5e-71 273   52%
Product
Methylenetetrahydrofolate reductase
Gene
JNB_01660
Organism
Janibacter sp. HTCC2649
1uniprot[Pubmed] 21075932
Genome sequence of the Marine Janibacter Sp. Strain HTCC2649.(J. Bacteriol.) [2011]
69
C6W9J0_ACTMD
(C6W9J0)
[query] 168 - 451 (460)
[subject] 7 - 287 (296)
2e-70 271   52%
Product
Methylenetetrahydrofolate reductase
Gene
Amir_1401
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
1uniprot
Complete genome sequence of Actinosynnema mirum type strain (101).(Stand. Genomic Sci.) [2009]
72
A4FAF8_SACEN
(A4FAF8)
[query] 193 - 451 (460)
[subject] 29 - 287 (294)
3e-69 267   54%
Product
Methylenetetrahydrofolate reductase
Gene
metF
SACE_1715
Organism
Saccharopolyspora erythraea (strain NRRL 23338)
1uniprot[Pubmed] 17369815
Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.(Nat. Biotechnol.) [2007]
76
Q0SHQ4_RHOSR
(Q0SHQ4)
[query] 185 - 447 (460)
[subject] 42 - 311 (335)
4e-68 263   54%
Product
Methylenetetrahydrofolate reductase
Gene
RHA1_ro01105
Organism
Rhodococcus sp. (strain RHA1)
1uniprot[Pubmed] 17030794
The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse.(Proc. Natl. Acad. Sci. U.S.A.) [2006]
78
D9UBI9_STRPR
(D9UBI9)
[query] 1 - 174 (460)
[subject] 1 - 169 (402)
9e-68 262   77%
Product
S-adenosylmethionine synthase
MAT
Methionine adenosyltransferase
Gene
samS
metK
Organism
Streptomyces pristinaespiralis
1uniprot[Pubmed] 21342465
Characterization of the 'pristinamycin supercluster' of Streptomyces pristinaespiralis.(Microb Biotechnol) [2011]
80
B0CN38_STRLA
(B0CN38)
[query] 3 - 257 (460)
[subject] 2 - 226 (401)
2e-67 261   58%
Product
S-adenosylmethionine synthase
MAT
Methionine adenosyltransferase
Gene
sfmS5
metK
Organism
Streptomyces lavendulae
1uniprot[Pubmed] 17981978
Characterization of the saframycin A gene cluster from Streptomyces lavendulae NRRL 11002 revealing a nonribosomal peptide synthetase system for assembling the unusual tetrapeptidyl skeleton in an iterative manner.(J. Bacteriol.) [2008]
81
D8HUS5_AMYMU
(D8HUS5)
[query] 168 - 447 (460)
[subject] 7 - 283 (294)
2e-67 261   50%
Product
Methylenetetrahydrofolate reductase
Gene
metF
AMED_2326
Organism
Amycolatopsis mediterranei (strain U-32)
1uniprot[Pubmed] 20567260
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism.(Cell Res.) [2010]
82
A2AXF1_STRCM
(A2AXF1)
[query] 1 - 174 (460)
[subject] 1 - 174 (408)
2e-67 261   76%
Product
S-adenosylmethionine synthase
MAT
Methionine adenosyltransferase
Gene
fnq12
metK
Organism
Streptomyces cinnamonensis
1uniprot[Pubmed] 17103476
A gene cluster for prenylated naphthoquinone and prenylated phenazine biosynthesis in Streptomyces cinnamonensis DSM 1042.(Chembiochem) [2006]
85
E4WIQ7_RHOE1
(E4WIQ7)
[query] 185 - 459 (460)
[subject] 31 - 312 (312)
4e-67 260   52%
Product
Methylenetetrahydrofolate reductase
Gene
REQ_27970
Organism
Rhodococcus equi (strain 103S)
Corynebacterium equi
1uniprot[Pubmed] 20941392
The genome of a pathogenic rhodococcus: cooptive virulence underpinned by key gene acquisitions.(PLoS Genet.) [2010]
88
E6SBW1_INTC7
(E6SBW1)
[query] 174 - 451 (460)
[subject] 28 - 302 (302)
8e-67 259   49%
Product
Methylenetetrahydrofolate reductase
Gene
Intca_1959
Organism
Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KIP)
1uniprot[Pubmed] 21304734
Complete genome sequence of Intrasporangium calvum type strain (7 KIP).(Stand. Genomic Sci.) [2010]
89
Q3HW35_STRAW
(Q3HW35)
[query] 1 - 174 (460)
[subject] 1 - 169 (402)
9e-67 259   78%
Product
S-adenosylmethionine synthase 2
MAT 2
Methionine adenosyltransferase 2
Gene
metK
metK2
Organism
Streptomyces avermitilis
1uniprot
Characterization of S-adenosylmethionine synthetase from Streptomyces avermitilis NRRL8165 and its effect on antibiotic production.(Enzyme Microb. Technol.) [2006]
90
METK_STRAW
(Q827Q0)
[query] 1 - 174 (460)
[subject] 1 - 169 (402)
9e-67 259   78%
Product
S-adenosylmethionine synthase
MAT
Methionine adenosyltransferase
Gene
metK
SAV_6874
Organism
Streptomyces avermitilis
1uniprot[Pubmed] 11572948 [Medline] 21477403
Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.(Proc. Natl. Acad. Sci. U.S.A.) [2001]
2uniprot[Pubmed] 12692562 [Medline] 22608306
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis.(Nat. Biotechnol.) [2003]
[pubmed all]
91
B0LJ35_9ACTO
(B0LJ35)
[query] 1 - 174 (460)
[subject] 1 - 172 (405)
1e-66 258   78%
Product
S-adenosylmethionine synthase
MAT
Methionine adenosyltransferase
Gene
lct52
metK
Organism
Streptomyces rishiriensis
1uniprot[Pubmed] 18070976
Biosynthetic investigations of lactonamycin and lactonamycin z: cloning of the biosynthetic gene clusters and discovery of an unusual starter unit.(Antimicrob. Agents Chemother.) [2008]
93
C1A0Z2_RHOE4
(C1A0Z2)
[query] 185 - 459 (460)
[subject] 42 - 323 (329)
1e-66 258   51%
Product
Methylenetetrahydrofolate reductase
Gene
metF
RER_35690
Organism
Rhodococcus erythropolis (strain PR4 / NBRC 100887)
1uniprot
Sequence analysis of three plasmids harboured in Rhodococcus erythropolis strain PR4.(Environ. Microbiol.) [2006]
98
E1ARJ8_STRAU
(E1ARJ8)
[query] 1 - 174 (460)
[subject] 1 - 169 (403)
2e-65 254   76%
Product
S-adenosylmethionine synthase
MAT
Methionine adenosyltransferase
Gene
metK
sa54
Organism
Streptomyces aureofaciens
1uniprot[Pubmed] 21393365
The role of two SARP family transcriptional regulators in regulation of the auricin gene cluster in Streptomyces aureofaciens CCM 3239.(Microbiology) [2011]
100
Q5YZ05_NOCFA
(Q5YZ05)
[query] 185 - 451 (460)
[subject] 37 - 310 (321)
3e-65 254   52%
Product
Methylenetetrahydrofolate reductase
Gene
metF
NFA_17400
Organism
Nocardia farcinica
1uniprot[Pubmed] 15466710
The complete genomic sequence of Nocardia farcinica IFM 10152.(Proc. Natl. Acad. Sci. U.S.A.) [2004]