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Resis_00010 : CDS information

close this sectionLocation

Organism
StrainHKI-237
Entry nameResistomycin
Contig
Start / Stop / Direction843 / 256 / - [in whole cluster]
843 / 256 / - [in contig]
Locationcomplement(256..843) [in whole cluster]
complement(256..843) [in contig]
TypeCDS
Length588 bp (195 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category4.1 transcriptional regulator
Productputative TetR family transcriptional regulator
Product (GenBank)RemQ protein
Gene
Gene (GenBank)remQ
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[14982421] A gene cluster encoding resistomycin biosynthesis in Streptomyces resistomycificus; exploring polyketide cyclization beyond linear and angucyclic patterns. (J Am Chem Soc. , 2004)
comment
resistomycin生合成gene cluster全体を異種性発現により同定。

RemQ: TetR-family regulator

特に詳細な記述はなし。
機能推定はAA配列相同性から。
Family/Domain
FD
IPR001647
comment
[IPR001647] Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal (Domain)

close this sectionSequence

selected fasta
>putative TetR family transcriptional regulator [RemQ protein]
MSSGSRGRRRGTGDTRAQILDAARSAFAAHGYQATTLRAVAYAAGVDASLIHHFFGPKEA
LFRAATGREPHLAGLTSGALASGDGERVLRACLDQWESPEQRAPVLAVVRSTLAHAPAAA
RLRDFVSVELQSALAGQLGGADAEVRAALVGSQLIGLMVARHVVPVEPLASADRDTVVGL
LAPALGRCLGETPEG
selected fasta
>putative TetR family transcriptional regulator [RemQ protein]
ATGAGTTCCGGCAGCAGGGGCCGCCGCCGGGGCACCGGCGACACGCGCGCGCAGATCCTC
GACGCGGCCCGGAGCGCCTTCGCCGCACACGGCTACCAGGCCACGACCCTGCGGGCCGTC
GCGTACGCCGCCGGCGTCGACGCCTCGCTCATCCACCACTTCTTCGGCCCCAAGGAGGCC
CTCTTCCGCGCGGCGACCGGCCGGGAACCGCACCTGGCCGGCCTCACATCGGGCGCGCTC
GCCTCCGGGGACGGGGAGCGTGTCCTGCGCGCCTGCCTCGACCAGTGGGAGTCACCGGAG
CAGCGCGCCCCGGTCCTCGCGGTGGTCCGCTCCACGCTCGCACACGCCCCGGCGGCGGCG
CGGCTGCGGGACTTCGTCTCCGTCGAGCTGCAATCCGCCCTCGCCGGGCAGCTCGGCGGC
GCGGACGCGGAGGTCCGGGCCGCCCTGGTCGGGTCCCAGCTGATCGGTCTGATGGTGGCG
CGTCACGTGGTCCCGGTGGAGCCGCTCGCCTCGGCCGACCGGGACACCGTGGTGGGTCTG
CTCGCTCCGGCCCTCGGAAGGTGCTTGGGCGAGACGCCGGAGGGCTGA

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR001647 DNA-binding HTH domain, TetR-type (Domain)
[19-32] 9.30000048475975e-07 PR00455 [40-63] 9.30000048475975e-07 PR00455
PR00455   HTHTETR
[13-73] PS50977
PS50977   HTH_TETR_2
[19-65] 7e-13 PF00440
PF00440   TetR_N
IPR009057 Homeodomain-like (Domain)
[3-89] 1.29999924468179e-14 SSF46689
SSF46689   Homeodomain_like
[6-65] 3.3e-19 G3DSA:1.10.10.60
G3DSA:1.10.10.60   Homeodomain-rel
IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal (Domain)
[81-192] 1.89999859865865e-30 SSF48498
SSF48498   TetR_like_C
IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal (Domain)
[84-189] 4.5e-37 G3DSA:1.10.357.10
G3DSA:1.10.357.10   TetR_C
SignalP No significant hit
TMHMM No significant hit
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