first first   Enter_00020 Enter_00020

Enter_00010 : CDS information

close this sectionLocation

Organism
Strain
Entry nameEnterocin
Contig
Start / Stop / Direction513 / 1,004 / + [in whole cluster]
513 / 1,004 / + [in contig]
Location513..1004 [in whole cluster]
513..1004 [in contig]
TypeCDS
Length492 bp (163 aa)
Click on the icon to see Genetic map.

close this sectionAnnotation

Category4.1 transcriptional regulator
Productputative MerR family transcriptional regulator
Product (GenBank)putative regulatory protein EncE
Gene
Gene (GenBank)encE
EC number
Keyword
Note
Note (GenBank)
Reference
ACC
PmId
[11137817] Cloning, sequencing and analysis of the enterocin biosynthesis gene cluster from the marine isolate 'Streptomyces maritimus': evidence for the derailment of an aromatic polyketide synthase. (Chem Biol. , 2000)
comment
enterocin と wailupemycinsの生合成をコードするgene clusterの同定。

EncE: Regulatory protein
EncEはMerR familyのregulatory proteinsに似ている。
Related Reference
ACC
Q93TP7
PmId
comment
Blast 395th, N末部分id48%, 6e-10
Pseudomonas putida_cadR
CadR

cadRは、カドミウム耐性を付与するCadmium-Transporting ATPase（cadA)の制御遺伝子。
cadRの挿入変異株はカドミウム耐性が低下し、また、cadR自身の転写活性が上昇していることを明らかにしている。
Family/Domain
FD
IPR000551, IPR015358
comment
[IPR000551] HTH transcriptional regulator, MerR (Domain)
[IPR015358] Transcription regulator MerR, DNA binding (Domain)

close this sectionSequence

selected fasta
>putative MerR family transcriptional regulator [putative regulatory protein EncE]
MAQERRMQIGEVAERTGLSLRTIRHYEEVGLIVPSARSKGGFPLYTQADVSRLMVIRRMK
PLDFSLEEMRDLLEITDRLGAQDDPPAPVERERLRERLDAYRKVADARCETLRARLAMAE
DFAATWRDGMNADARARSASERATSGGPLRRLWLTSDAPGLAG
selected fasta
>putative MerR family transcriptional regulator [putative regulatory protein EncE]
ATGGCGCAAGAGCGGCGCATGCAGATCGGCGAGGTCGCCGAGCGCACAGGATTGTCGTTG
CGCACGATCCGGCACTACGAAGAGGTCGGCCTCATCGTTCCCTCCGCCCGCAGCAAGGGC
GGCTTCCCTCTCTACACTCAGGCCGACGTCAGTCGGCTCATGGTGATTCGGCGTATGAAG
CCGCTGGATTTCTCCCTTGAGGAGATGCGGGACCTGCTGGAGATCACTGACAGGCTCGGC
GCCCAGGATGATCCGCCCGCACCTGTGGAGCGCGAGCGACTCCGTGAGCGACTTGACGCG
TACCGCAAGGTGGCCGACGCGCGGTGCGAGACACTGCGCGCGCGACTGGCGATGGCCGAG
GACTTCGCCGCCACGTGGCGTGACGGGATGAATGCGGATGCCCGAGCTCGGTCGGCAAGT
GAGCGGGCTACTTCCGGGGGCCCTCTGCGGAGGCTCTGGCTCACGAGTGATGCACCCGGT
CTTGCCGGGTAG

close this sectionFeature

BLASTP
Database:UniProtKB:2011_09 		show BLAST table
InterPro
Database:interpro:38.0
IPR000551 Transcription regulator HTH, MerR (Domain)
[9-45] 8.9e-13 PF00376
PF00376   MerR
[7-76] 8.49999291746323e-32 SM00422
SM00422   HTH_MERR
[8-19] 4.39999967439747e-07 PR00040 [19-32] 4.39999967439747e-07 PR00040 [43-63] 4.39999967439747e-07 PR00040
PR00040   HTHMERR
[10-32] PS00552
PS00552   HTH_MERR_1
[6-75] PS50937
PS50937   HTH_MERR_2
IPR009061 DNA binding domain, putative (Domain)
[7-133] 2.49999811956465e-26 SSF46955
SSF46955   Putativ_DNA_bind
IPR015358 Transcription regulator MerR, DNA binding (Domain)
[50-100] 2.1e-08 PF09278
PF09278   MerR-DNA-bind
SignalP No significant hit
TMHMM No significant hit
first first   Enter_00020 Enter_00020
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